"I should have more faith," he said; "I ought to know by this time that when a fact appears opposed to a long train of deductions it invariably proves to be capable of bearing some other interpretation."

...the life of the planet began the long, slow process of modulating and regulating the physical conditions of the planet. The oxygen in today's atmosphere is almost entirely the result of photosynthetic living, which had its start with the appearance of blue-green algae among the microorganisms.

Combination does not produce though mergers and combinations are still the accepted panacea. In Big business there appears to be increasing aridity, bureaucracy, and stultifying sacrifice of initiative and above all fear.

Question: Account for the delicate shades of colour sometimes seen on the inside of an oyster shell. State and explain the appearance presented when a beam of light falls upon a sheet of glass on which very fine equi-distant parallel lines have been scratched very close to one another.
Answer: The delicate shades are due to putrefaction; the colours always show best when the oyster has been a bad one. Hence they are considered a defect and are called chromatic aberration.
The scratches on the glass will arrange themselves in rings round the light, as any one may see at night in a tram car.

A catalyst is a substance which alters the velocity of a chemical reaction without appearing in the final products.

A process which led from the amoeba to man appeared to the philosophers to be obviously a progress -- though whether the amoeba would agree with this opinion is not known.

All things appear and disappear because of the concurrence of causes and conditions. Nothing ever exists entirely alone; everything is in relationship to everything else.

At the sight of a single bone, of a single piece of bone, I recognize and reconstruct the portion of the whole from which it would have been taken. The whole being to which this fragment belonged appears in my mind's eye.

But here it may be objected, that the present Earth looks like a heap of Rubbish and Ruines; And that there are no greater examples of confusion in Nature than Mountains singly or jointly considered; and that there appear not the least footsteps of any Art or Counsel either in the Figure and Shape, or Order and Disposition of Mountains and Rocks. Wherefore it is not likely they came so out of God's hands ... To which I answer, That the present face of the Earth with all its Mountains and Hills, its Promontaries and Rocks, as rude and deformed as they appear, seems to me a very beautiful and pleasant object, and with all the variety of Hills, and Valleys, and Inequalities far more grateful to behold, than a perfectly level Countrey without any rising or protuberancy, to terminate the sight: As anyone that hath but seen the Isle of Ely, or any the like Countrey must need acknowledge.

But I think that in the repeated and almost entire changes of organic types in the successive formations of the earth—in the absence of mammalia in the older, and their very rare appearance (and then in forms entirely. unknown to us) in the newer secondary groups—in the diffusion of warm-blooded quadrupeds (frequently of unknown genera) through the older tertiary systems—in their great abundance (and frequently of known genera) in the upper portions of the same series—and, lastly, in the recent appearance of man on the surface of the earth (now universally admitted—in one word, from all these facts combined, we have a series of proofs the most emphatic and convincing,—that the existing order of nature is not the last of an uninterrupted succession of mere physical events derived from laws now in daily operation: but on the contrary, that the approach to the present system of things has been gradual, and that there has been a progressive development of organic structure subservient to the purposes of life.

But it will be found... that one universal law prevails in all these phenomena. Where two portions of the same light arrive in the eye by different routes, either exactly or very nearly in the same direction, the appearance or disappearance of various colours is determined by the greater or less difference in the lengths of the paths.

Considered as a mere question of physics, (and keeping all moral considerations entirely out of sight,) the appearance of man is a geological phenomenon of vast importance, indirectly modifying the whole surface of the earth, breaking in upon any supposition of zoological continuity, and utterly unaccounted for by what we have any right to call the laws of nature.

Every complete set of chromosomes contains the full code; so there are, as a rule, two copies of the latter in the fertilized egg cell, which forms the earliest stage of the future individual. In calling the structure of the chromosome fibres a code-script we mean that the all-penetrating mind, once conceived by Laplace, to which every causal connection lay immediately open, could tell from their structure whether the egg would develop, under suitable conditions, into a black cock or into a speckled hen, into a fly or a maize plant, a rhododendron, a beetle, a mouse or a woman. To which we may add, that the appearances of the egg cells are very often remarkably similar; and even when they are not, as in the case of the comparatively gigantic eggs of birds and reptiles, the difference is not so much in the relevant structures as in the nutritive material which in these cases is added for obvious reasons.
But the term code-script is, of course, too narrow. The chromosome structures are at the same time instrumental in bringing about the development they foreshadow. They are law-code and executive power?or, to use another simile, they are architect's plan and builder's craft-in one.

Every river appears to consist of a main trunk, fed from a variety of branches, each running in a valley proportional to its size, and all of them together forming a system of vallies, communicating with one another, and having such a nice adjustment of their declivities that none of them join the principal valley on too high or too low a level; a circumstance which would be infinitely improbable if each of these vallies were not the work of the stream that flows in it.

I think I may fairly make two postulata. First, that food is necessary to the existence of man.
Secondly, that the passion between the sexes is necessary, and will remain nearly in its present state.
These two laws ever since we have had any knowledge of mankind, appear to have been fixed laws of our nature; and, as we have not hitherto seen any alteration in them, we have no right to conclude that they will ever cease to be what they now are, without an immediate act of power in that Being who first arranged the system of the universe, and for the advantage of his creatures, still executes, according to fixed laws, all its various operations.

If a solution fails to appear ... and yet we feel success is just around the corner, try resting for a while. ... Like the early morning frost, this intellectual refreshment withers the parasitic and nasty vegetation that smothers the good seed. Bursting forth at last is the flower of truth.

In all matters of opinion and science ... the difference between men is ... oftener found to lie in generals than in particulars; and to be less in reality than in appearance. An explication of the terms commonly ends the controversy, and the disputants are surprised to find that they had been quarrelling, while at bottom they agreed in their judgement.

It appears that anything you say about the way that theory and experiment may interact is likely to be correct, and anything you say about the way that theory and experiment must interact is likely to be wrong.

It is one of the triumphs of human wit ... to conquer by humility and submissiveness ... to make oneself small in order to appear great ... such ... are often the expedients of the neurotic.

It seems to me that the evidence ... is opposed to the view that the spirals are individual galaxies comparable with our own. In fact, there appears as yet no reason for modifying the tentative hypothesis that the spirals are not composed of typical stars at all, but are truly nebulous objects.
[Contradicting the view of Heber Curtis during the Shapley-Curtis debate on 26 Apr 1920 to the National Academy of Sciences.]

It was Plato, according to Sosigenes, who set this as a problem for those concerned with these things, through what suppositions of uniform and ordered movements the appearances concerning the movements of the wandering heavenly bodies could be preserved.

Let people who have to observe sickness and death look back and try to register in their observation the appearances which have preceded relapse, attack or death, and not assert that there were none, or that there were not the right ones. A want of the habit of observing conditions and an inveterate habit of taking averages are each of them often equally misleading.

My original decision to devote myself to science was a direct result of the discovery which has never ceased to fill me with enthusiasm since my early youth—the comprehension of the far from obvious fact that the laws of human reasoning coincide with the laws governing the sequences of the impressions we receive from the world about us; that, therefore, pure reasoning can enable man to gain an insight into the mechanism of the latter. In this connection, it is of paramount importance that the outside world is something independent from man, something absolute, and the quest for the laws which apply to this absolute appeared to me as the most sublime scientific pursuit in life.

perhaps to move
His laughter at their quaint opinions wide
Hereafter; when they come to model heav'n,
And calculate the stars, how they will wield
The mighty frame; how build, un-build, contrive,
To save appearances; how gird the sphere With centric and eccentric scribbled o'er, Cycle and epicycle, orb in orb.

Philosophy would long ago have reached a high level if our predecessors and fathers had put this into practice; and we would not waste time on the primary difficulties, which appear now as severe as in the first centuries which noticed them. We would have the experience of assured phenomena, which would serve as principles for a solid reasoning; truth would not be so deeply sunken; nature would have taken off most of her envelopes; one would see the marvels she contains in all her individuals. ...

Quantum theory thus reveals a basic oneness of the universe. It shows that we cannot decompose the world into independently existing smallest units. As we penetrate into matter, nature does not show us any isolated “building blocks,” but rather appears as a complicated web of relations between the various parts of the whole. These relations always include the observer in an essential way. The human observer constitute the final link in the chain of observational processes, and the properties of any atomic object can be understood only in terms of the object's interaction with the observer.

Scientists are the easiest to fool. ... They think in straight, predictable, directable, and therefore misdirectable, lines. The only world they know is the one where everything has a logical explanation and things are what they appear to be. Children and conjurors—they terrify me. Scientists are no problem; against them I feel quite confident.

The appearance of Professor Benjamin Peirce, whose long gray hair, straggling grizzled beard and unusually bright eyes sparkling under a soft felt hat, as he walked briskly but rather ungracefully across the college yard, fitted very well with the opinion current among us that we were looking upon a real live genius, who had a touch of the prophet in his make-up.

The fundamental problem in the origin of species is not the origin of differences in appearance, since these arise at the level of the geographical race, but the origin of genetic segregation. The test of species-formation is whether, when two forms meet, they interbreed and merge, or whether they keep distinct.

The generation of seeds ... is therefore marvelous and analogous to the other productions of living things. For first of all an umbilicus appears. ... Its extremity gradually expands and after gathering a colliquamentous ichor becomes analogous to an amnion. ... In the course of time the seed or fetus begins to become visible.

The hypotheses which we accept ought to explain phenomena which we have observed. But they ought to do more than this; our hypotheses ought to foretell phenomena which have not yet been observed; ... because if the rule prevails, it includes all cases; and will determine them all, if we can only calculate its real consequences. Hence it will predict the results of new combinations, as well as explain the appearances which have occurred in old ones. And that it does this with certainty and correctness, is one mode in which the hypothesis is to be verified as right and useful.

The indescribable pleasure—which pales the rest of life's joys—is abundant compensation for the investigator who endures the painful and persevering analytical work that precedes the appearance of the new truth, like the pain of childbirth. It is true to say that nothing for the scientific scholar is comparable to the things that he has discovered. Indeed, it would be difficult to find an investigator willing to exchange the paternity of a scientific conquest for all the gold on earth. And if there are some who look to science as a way of acquiring gold instead of applause from the learned, and the personal satisfaction associated with the very act of discovery, they have chosen the wrong profession.

The map appears to us more real than the land.

The mountains too, at a distance, appear airy masses and smooth, but seen near at hand they are rough.

The whole strenuous intellectual work of an industrious research worker would appear, after all, in vain and hopeless, if he were not occasionally through some striking facts to find that he had, at the end of all his criss-cross journeys, at last accomplished at least one step which was conclusively nearer the truth.

Though much new light is shed by ... studies in radioactivity, the nucleus of the atom, with its hoard of energy, thus continues to present us with a fascinating mystery. ... Our assault on atoms has broken down the outer fortifications. We feel that we know the fundamental rules according to which the outer part of the atom is built. The appearance and properties of the electron atmosphere are rather familiar. Yet that inner citadel, the atomic nucleus, remains unconquered, and we have reason to believe that within this citadel is secreted a great treasure. Its capture may form the main objective of the physicists’ next great drive.

We often observe in lawyers, who as Quicquid agunt homines is the matter of law suits, are sometimes obliged to pick up a temporary knowledge of an art or science, of which they understood nothing till their brief was delivered, and appear to be much masters of it.

When a scientist is ahead of his times, it is often through misunderstanding of current, rather than intuition of future truth. In science there is never any error so gross that it won't one day, from some perspective, appear prophetic.

[The octopus has] an amazing skin, because there are up to 20 million of these chromatophore pigment cells and to control 20 million of anything is going to take a lot of processing power. ... These animals have extraordinarily large, complicated brains to make all this work. ... And what does this mean about the universe and other intelligent life? The building blocks are potentially there and complexity will arise. Evolution is the force that's pushing that. I would expect, personally, a lot of diversity and a lot of complicated structures. It may not look like us, but my personal view is that there is intelligent life out there.