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Home > Category Index for Science Quotations > Category Index M > Category: Mechanism

Mechanism Quotes (102 quotes)

[The more science discovers and] the more comprehension it gives us of the mechanisms of existence, the more clearly does the mystery of existence itself stand out.
Julian Huxley and Aldous Huxley, Aldous Huxley, 1894-1963: A Memorial Volume (1965), 21.
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[The] structural theory is of extreme simplicity. It assumes that the molecule is held together by links between one atom and the next: that every kind of atom can form a definite small number of such links: that these can be single, double or triple: that the groups may take up any position possible by rotation round the line of a single but not round that of a double link: finally that with all the elements of the first short period [of the periodic table], and with many others as well, the angles between the valencies are approximately those formed by joining the centre of a regular tetrahedron to its angular points. No assumption whatever is made as to the mechanism of the linkage. Through the whole development of organic chemistry this theory has always proved capable of providing a different structure for every different compound that can be isolated. Among the hundreds of thousands of known substances, there are never more isomeric forms than the theory permits.
Presidential Address to the Chemical Society (16 Apr 1936), Journal of the Chemical Society (1936), 533.
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Surtout l’astronomie et l’anatomie sont les deux sciences qui nous offrent le plus sensiblement deux grands caractères du Créateur; l’une, son immensité, par les distances, la grandeur, et le nombre des corps célestes; l’autre, son intelligence infinie, par la méchanique des animaux.
Above all, astronomy and anatomy are the two sciences which present to our minds most significantly the two grand characteristics of the Creator; the one, His immensity, by the distances, size, and number of the heavenly bodies; the other, His infinite intelligence, by the mechanism of animate beings.
Original French and translation in Craufurd Tait Ramage (ed.) Beautiful Thoughts from French and Italian Authors (1866), 119-120.
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The constancy of the internal environment is the condition for free and independent life: the mechanism that makes it possible is that which assured the maintenance, with the internal environment, of all the conditions necessary for the life of the elements.
Lectures on the Phenomena of Life Common to Animals and Plants (1878), trans. Hebbel E. Hoff, Roger Guillemin and Lucienne Guillemin (1974), 84.
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A bird is an instrument working according to mathematical law, which instrument it is within the capacity of man to reproduce with all its movements, but not with a corresponding degree of strength, though it is deficient only in the power of maintaining equilibrium. We may therefore say that such an instrument constructed by man is lacking in nothing except the life of the bird, and this life must needs be supplied from that of man.
'Of the Bird's Movement' from Codice Atlantico 161 r.a., in Leonardo da Vinci's Notebooks, trans. E. MacCurdy (1906), Vol. 1, 153.
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A calculating engine is one of the most intricate forms of mechanism, a telegraph key one of the simplest. But compare their value.
From chapter 'Jottings from a Note-Book', in Canadian Stories (1918), 174.
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Adrenalin does not excite sympathetic ganglia when applied to them directly, as does nicotine. Its effective action is localised at the periphery. The existence upon plain muscle of a peripheral nervous network, that degenerates only after section of both the constrictor and inhibitory nerves entering it, and not after section of either alone, has been described. I find that even after such complete denervation, whether of three days' or ten months' duration, the plain muscle of the dilatator pupillae will respond to adrenalin, and that with greater rapidity and longer persistence than does the iris whose nervous relations are uninjured. Therefore it cannot be that adrenalin excites any structure derived from, and dependent for its persistence on, the peripheral neurone. But since adrenalin does not evoke any reaction from muscle that has at no time of its life been innervated by the sympathetic, the point at which the stimulus of the chemical excitant is received, and transformed into what may cause the change of tension of the muscle fibre, is perhaps a mechanism developed out of the muscle cell in response to its union with the synapsing sympathetic fibre, the function of which is to receive and transform the nervous impulse. Adrenalin might then be the chemical stimulant liberated on each occasion when the impulse arrives at the periphery.
'On the Action of Adrenalin', Proceedings of the Physiological Society, 21 May 1904, in The Journal of Physiology 1904, 31, xxi.
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Again, it [the Analytical Engine] might act upon other things besides number, were objects found whose mutual fundamental relations could be expressed by those of the abstract science of operations, and which should be also susceptible of adaptations to the action of the operating notation and mechanism of the engine. Supposing for instance, that the fundamental relations of pitched sounds in the science of harmony and of musical composition were susceptible of such expression and adaptations, the engine might compose elaborate and scientific pieces of music of any degree of complexity or extent.
In Richard Taylor (ed.), 'Translator’s Notes to M. Menabrea’s Memoir', Scientific Memoirs, Selected from the Transactions of Foreign Academies and Learned Societies and from Foreign Journals (1843), 3, Note A, 694. Her notes were appended to L.F. Menabrea, of Turin, Officer of the Military Engineers, 'Article XXIX: Sketch of the Analytical Engine invented by Charles Babbage Esq.', Bibliothèque Universelle de Gnve (Oct 1842), No. 82.
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All scientists must focus closely on limited targets. Whether or not one’s findings on a limited subject will have wide applicability depends to some extent on chance, but biologists of superior ability repeatedly focus on questions the answers to which either have wide ramifications or lead to new areas of investigation. One procedure that can be effective is to attempt both reduction and synthesis; that is, direct a question at a phenomenon on one integrative level, identify its mechanism at a simpler level, then extrapolate its consequences to a more complex level of integration.
In 'Scientific innovation and creativity: a zoologist’s point of view', American Zoologist (1982), 22, 230-231,
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All the inventions and devices ever constructed by the human hand or conceived by the human mind, no matter how delicate, how intricate and complicated, are simple, childish toys compared with that most marvelously wrought mechanism, the human body. Its parts are far more delicate, and their mutual adjustments infinitely more accurate, than are those of the most perfect chronometer ever made.
In Plain Facts For Old and Young: Embracing the Natural History and Hygiene of Organic Life (1879, 1887), Revised Ed., 332.
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And for rejecting such a Medium, we have the Authority of those the oldest and most celebrated Philosophers of Greece and Phoenicia, who made a Vacuum, and Atoms, and the Gravity of Atoms, the first Principles of their Philosophy; tacitly attributing Gravity to some other Cause than dense Matter. Later Philosophers banish the Consideration of such a Cause out of natural Philosophy, feigning Hypotheses for explaining all things mechanically, and referring other Causes to Metaphysicks: Whereas the main Business of natural Philosophy is to argue from Phaenomena without feigning Hypotheses, and to deduce Causes from Effects, till we come to the very first Cause, which certainly is not mechanical; and not only to unfold the Mechanism of the World, but chiefly to resolve these and such like Questions. What is there in places almost empty of Matter, and whence is it that the Sun and Planets gravitate towards one another, without dense Matter between them? Whence is it that Nature doth nothing in vain; and whence arises all that Order and Beauty which we see in the World? ... does it not appear from phaenomena that there is a Being incorporeal, living, intelligent, omnipresent, who in infinite space, as it were in his Sensory, sees the things themselves intimately, and thoroughly perceives them, and comprehends them wholly by their immediate presence to himself.
In Opticks, (1704, 2nd. Ed. 1718), Book 3, Query 28, 343-5. Newton’s reference to “Nature does nothing in vain” recalls the axiom from Aristotle, which may be seen as “Natura nihil agit frustra” in the Aristotle Quotes on this web site.
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As for me ... I would much rather be a perfected ape than a degraded Adam. Yes, if it is shown to me that my humble ancestors were quadrupedal animals, arboreal herbivores, brothers or cousins of those who were also the ancestors of monkeys and apes, far from blushing in shame for my species because of its genealogy and parentage, I will be proud of all that evolution has accomplished, of the continuous improvement which takes us up to the highest order, of the successive triumphs that have made us superior to all of the other species ... the splendid work of progress.
I will conclude in saying: the fixity of species is almost impossible, it contradicts the mode of succession and of the distribution of species in the sequence of extant and extinct creatures. It is therefore extremely likely that species are variable and are subject to evolution. But the causes, the mechanisms of this evolution are still unknown.
'Discussion sur la Machoire Humaine de la Naulette (Belgique)', Bulletin de la Societé d'Anthropologie de Paris, 2nd Series, I (1866), 595. Trans. Erik Trinkaus and Pat Shipman, The Neanderthals: Changing the Image of Mankind (1993), 103-4.
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Cell genetics led us to investigate cell mechanics. Cell mechanics now compels us to infer the structures underlying it. In seeking the mechanism of heredity and variation we are thus discovering the molecular basis of growth and reproduction. The theory of the cell revealed the unity of living processes; the study of the cell is beginning to reveal their physical foundations.
Recent Advances in Cytology (1937), 562.
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Contrary to popular parlance, Darwin didn't discover evolution. He uncovered one (most would say the) essential mechanism by which it operates: natural selection. Even then, his brainstorm was incomplete until the Modern Synthesis of the early/mid-20th century when (among other things) the complementary role of genetic heredity was fully realized. Thousands upon thousands of studies have followed, providing millions of data points that support this understanding of how life on Earth has come to be as it is.
In online article, 'The Day That Botany Took on Bobby Jindal by Just Being Itself', Huffington Post (5 Aug 2013).
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Darwinian evolution is the cornerstone of modern biology. But if we accept Darwin’s mechanism for changes in living things, we must postulate another prebiotic form of evolution, which may be described as chemical evolution.
In 'Cosmochemistry The Earliest Evolution', The Science Teacher (Oct 1983), 50, No. 7, 34.
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During the half-century that has elapsed since the enunciation of the cell-theory by Schleiden and Schwann, in 1838-39, it has became ever more clearly apparent that the key to all ultimate biological problems must, in the last analysis, be sought in the cell. It was the cell-theory that first brought the structure of plants and animals under one point of view by revealing their common plan of organization. It was through the cell-theory that Kolliker and Remak opened the way to an understanding of the nature of embryological development, and the law of genetic continuity lying at the basis of inheritance. It was the cell-­theory again which, in the hands of Virchaw and Max Schultze, inaugurated a new era in the history of physiology and pathology, by showing that all the various functions of the body, in health and in disease, are but the outward expression of cell­-activities. And at a still later day it was through the cell-theory that Hertwig, Fol, Van Beneden, and Strasburger solved the long-standing riddle of the fertilization of the egg, and the mechanism of hereditary transmission. No other biological generalization, save only the theory of organic evolution, has brought so many apparently diverse phenomena under a common point of view or has accomplished more far the unification of knowledge. The cell-theory must therefore be placed beside the evolution-theory as one of the foundation stones of modern biology.
In The Cell in Development and Inheritance (1896), 1.
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Education is a mechanism for inducing change and for providing the means of accommodation and adjustment to change. At the same time, as an institution, education is given the responsibility for insuring the preservation and transfer and therefore, the continuity of society’s knowledge, skills, and values.
As quoted by Luther H. Evans and George E. Arnstein (eds.), in Automation and the Challenge to Education: Proceedings of a Symposium (1962).
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Essentially only one thing in life interests us: our psychical constitution, the mechanism of which was and is wrapped in darkness. All human resources, art, religion, literature, philosophy and historical sciences, all of them join in bringing lights in this darkness. But man has still another powerful resource: natural science with its strictly objective methods. This science, as we all know, is making huge progress every day. The facts and considerations which I have placed before you at the end of my lecture are one out of numerous attempts to employ a consistent, purely scientific method of thinking in the study of the mechanism of the highest manifestations of life in the dog, the representative of the animal kingdom that is man's best friend.
'Physiology of Digestion', Nobel Lecture (12 Dec 1904). In Nobel Lectures: Physiology or Medicine 1901-1921 (1967), 134
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Every breath you draw, every accelerated beat of your heart in the emotional periods of your oratory depend upon highly elaborated physical and chemical reactions and mechanisms which nature has been building up through a million centuries. If one of these mechanisms, which you owe entirely to your animal ancestry, were to be stopped for a single instant, you would fall lifeless on the stage. Not only this, but some of your highest ideals of human fellowship and comradeship were not created in a moment, but represent the work of ages.
Quoted in Closing Address by Dr. Henry Sloane Coffin, president of the Union Theological Seminary, New York, at the Memorial Service for Osborn at St. Bartholomew's Church, N.Y. (18 Dec 1935). In 'Henry Fairfield Osborn', Supplement to Natural History (Feb 1936), 37:2, 133-34. Bound in Kofoid Collection of Pamphlets on Biography, University of California.
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For the first time there was constructed with this machine [locomotive engine] a self-acting mechanism in which the interplay of forces took shape transparently enough to discern the connection between the heat generated and the motion produced. The great puzzle of the vital force was also immediately solved for the physiologist in that it became evident that it is more than a mere poetic comparison when one conceives of the coal as the food of the locomotive and the combustion as the basis for its life.
'Leid und Freude in der Naturforschung', Die Gartenlaube (1870), 359. Trans. Kenneth L. Caneva, Robert Mayer and the Conservation of Energy (1993), 145.
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For truly in nature there are many operations that are far more than mechanical. Nature is not simply an organic body like a clock, which has no vital principle of motion in it; but it is a living body which has life and perception, which are much more exalted than a mere mechanism or a mechanical motion.
The Principles of the Most Ancient and Modern Philosophy (1692), trans. and ed. Allison Coudert and Taylor Corse (1996), 64.
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Genetics has enticed a great many explorers during the past two decades. They have labored with fruit-flies and guinea-pigs, with sweet peas and corn, with thousands of animals and plants in fact, and they have made heredity no longer a mystery but an exact science to be ranked close behind physics and chemistry in definiteness of conception. One is inclined to believe, however, that the unique magnetic attraction of genetics lies in the vision of potential good which it holds for mankind rather than a circumscribed interest in the hereditary mechanisms of the lowly species used as laboratory material. If man had been found to be sharply demarcated from the rest of the occupants of the world, so that his heritage of physical form, of physiological function, and of mental attributes came about in a superior manner setting him apart as lord of creation, interest in the genetics of the humbler organisms—if one admits the truth—would have flagged severely. Biologists would have turned their attention largely to the ways of human heredity, in spite of the fact that the difficulties encountered would have rendered progress slow and uncertain. Since this was not the case, since the laws ruling the inheritance of the denizens of the garden and the inmates of the stable were found to be applicable to prince and potentate as well, one could shut himself up in his laboratory and labor to his heart's content, feeling certain that any truth which it fell to his lot to discover had a real human interest, after all.
Mankind at the Crossroads (1923), v-vi.
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Genius and science have burst the limits of space, and few observations, explained by just reasoning, have unveiled the mechanism of the universe. Would it not also be glorious for man to burst the limits of time, and, by a few observations, to ascertain the history of this world, and the series of events which preceded the birth of the human race?
'Preliminary discourse', to Recherches sur les Ossemens Fossiles (1812), trans. R. Kerr Essay on the Theory of the Earth (1813), 3-4.
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Edwin Grant Conklin quote: Heredity is to-day the central problem of biology. This problem may be approached from many sides—tha
Heredity is to-day the central problem of biology. This problem may be approached from many sides—that of the breeder, the experimenter, the statistician, the physiologist, the embryologist, the cytologist—but the mechanism of heredity can be studied best by the investigation of the germ cells and their development.
From Address of the vice-president and chairman of Section F, Zoology, American Association for the Advancement of Science, Chicago Meeting (1907-8). Published in 'The Mechanism of Heredity', Science (17 Jan 1908), 27, No. 691, 89-90.
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I am among those who think that science has great beauty. A scientist in his laboratory is not only a technician: he is also a child placed before natural phenomena which impress him like a fairy tale. We should not allow it to be believed that all scientific progress can be reduced to mechanisms, machines, gearings, even though such machinery has its own beauty.
During a debate in Madrid, ',The Future of Culture' (1933). In Eve Curie Labouisse, Eve Curie and Vincent Sheean, Madame Curie (1937), 341
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I recognize nothing that is not material. In physics, chemistry and biology I see only mechanics. The Universe is nothing but an infinite and complex mechanism. Its complexity is so great that it borders on willfulness, suddenness, and randomness; it gives the illusion of free will possessed by conscious beings.
In Monism of the Universe (1931).
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I remember vividly my student days, spending hours at the light microscope, turning endlessly the micrometric screw, and gazing at the blurred boundary which concealed the mysterious ground substance where the secret mechanisms of cell life might be found.
Nobel Lecture, The Coming Age of the Cell, 12 Dec 1974
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I should be the last to discard the law of organic heredity ... but the single word “heredity” cannot dispense science from the duty of making every possible inquiry into the mechanism of organic growth and of organic formation. To think that heredity will build organic beings without mechanical means is a piece of unscientific mysticism.
In 'On the Principles of Animal Morphology', Proceedings of the Royal Society of Edinburgh (1888), 15, 294-295. Original as Letter to Mr John Murray, communicated to the Society by Professor Sir William Turner. Page given as in collected volume published 1889.
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I think that in order to achieve progress in the study of language and human cognitive faculties in general it is necessary first to establish 'psychic distance' from the 'mental facts' to which Köhler referred, and then to explore the possibilities for developing explanatory theories... We must recognize that even the most familiar phenomena require explanation and that we have no privileged access to the underlying mechanisms, no more so than in physiology or physics.
Language and Mind (1972, enlarged edition), 26.
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I think that intelligence does not emerge from a handful of very beautiful principles—like physics. It emerges from perhaps a hundred fundamentally different kinds of mechanisms that have to interact just right. So, even if it took only four years to understand them, it might take four hundred years to unscramble the whole thing.
As quoted from an interview with author Jeremy Bernstein, in Science Observed: Essays Out of My Mind (1982), 44.
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I think that the event which, more than anything else, led me to the search for ways of making more powerful radio telescopes, was the recognition, in 1952, that the intense source in the constellation of Cygnus was a distant galaxy—1000 million light years away. This discovery showed that some galaxies were capable of producing radio emission about a million times more intense than that from our own Galaxy or the Andromeda nebula, and the mechanisms responsible were quite unknown. ... [T]he possibilities were so exciting even in 1952 that my colleagues and I set about the task of designing instruments capable of extending the observations to weaker and weaker sources, and of exploring their internal structure.
From Nobel Lecture (12 Dec 1974). In Stig Lundqvist (ed.), Nobel Lectures, Physics 1971-1980 (1992), 187.
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In a sense, genetics grew up as an orphan. In the beginning botanists and zoologists were often indifferent and sometimes hostile toward it. “Genetics deals only with superficial characters”, it was often said. Biochemists likewise paid it little heed in its early days. They, especially medical biochemists, knew of Garrod’s inborn errors of metabolism and no doubt appreciated them in the biochemical sense and as diseases; but the biological world was inadequately prepared to appreciate fully the significance of his investigations and his thinking. Geneticists, it should be said, tended to be preoccupied mainly with the mechanisms by which genetic material is transmitted from one generation to, the next.
'Genes and Chemical Reactions In Neurospora', Nobel Lecture, 11 Dec 1958. In Nobel Lectures: Physiology or Medicine 1942-1962 (1964), 598.
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In its essence, the theory of natural selection is primarily an attempt to give an account of the probable mechanism of the origin of the adaptations of the organisms to their environment, and only secondarily an attempt to explain evolution at large. Some modern biologists seem to believe that the word 'adaptation' has teleological connotations, and should therefore be expunged from the scientific lexicon. With this we must emphatically disagree. That adaptations exist is so evident as to be almost a truism, although this need not mean that ours is the best of all possible worlds. A biologist has no right to close his eyes to the fact that the precarious balance between a living being and its environment must be preserved by some mechanism or mechanisms if life is to endure.
Genetics and Origin of Species (1937), 150.
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In science it is no crime to be wrong, unless you are (inappropriately) laying claim to truth. What matters is that science as a whole is a self-correcting mechanism in which both new and old notions are constantly under scrutiny. In other words, the edifice of scientific knowledge consists simply of a body of observations and ideas that have (so far) proven resistant to attack, and that are thus accepted as working hypotheses about nature.
In The Monkey in the Mirror: Essays on the Science of What Makes Us Human (2003), 9.
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In the vast cosmical changes, the universal life comes and goes in unknown quantities ... sowing an animalcule here, crumbling a star there, oscillating and winding, ... entangling, from the highest to the lowest, all activities in the obscurity of a dizzying mechanism, hanging the flight of an insect upon the movement of the earth... Enormous gearing, whose first motor is the gnat, and whose last wheel is the zodiac.
Victor Hugo and Charles E. Wilbour (trans.), Les Misérables (1862), 41.
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Is the very mechanism for the universe to come into being meaningless or unworkable or both unless the universe is guaranteed to produce life, consciousness and observership somewhere and for some little time in its history-to-be?
Quoted in P.C.W. Davies, God and the New Physics (1984), 39, from J.A. Wheeler, 'Genesis and observership', Foundational Problems in the Special Science (1977), 39.
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Isolating mechanisms are biological properties of individuals that prevent the interbreeding of populations that are actually or potentially sympatric.
Animal Species and Evolution (1963), 91.
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It appears unlikely that the role of the genes in development is to be understood so long as the genes are considered as dictatorial elements in the cellular economy. It is not enough to know what a gene does when it manifests itself. One must also know the mechanisms determining which of the many gene-controlled potentialities will be realized.
'The Role of the Cytoplasm in Heredity', in William D. McElroy and Bentley Glass (eds.), A Symposium on the Chemical Basis of Heredity (1957), 162.
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It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
[Concluding remark in the paper by Watson and Crick announcing discovery of the structure of DNA.]
In J.D. Watson and F.H.C. Crick, 'A Structure for Deoxyribose Nucleic Acid,' Letter in Nature (25 Apr 1953), 171, 738. Quoted in Francis Crick, What Mad Pursuit (1990), 66.
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It is known that the mathematics prescribed for the high school [Gymnasien] is essentially Euclidean, while it is modern mathematics, the theory of functions and the infinitesimal calculus, which has secured for us an insight into the mechanism and laws of nature. Euclidean mathematics is indeed, a prerequisite for the theory of functions, but just as one, though he has learned the inflections of Latin nouns and verbs, will not thereby be enabled to read a Latin author much less to appreciate the beauties of a Horace, so Euclidean mathematics, that is the mathematics of the high school, is unable to unlock nature and her laws.
In Die Mathematik die Fackelträgerin einer neuen Zeit (1889), 37-38. As translated in Robert Édouard Moritz, Memorabilia Mathematica; Or, The Philomath’s Quotation-book (1914), 112.
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It is the intertwined and interacting mechanisms of evolution and ecology, each of which is at the same time a product and a process, that are responsible for life as we see it, and as it has been.
In Evolutionary Paleoecology of the Marine Biosphere (1973), 58.
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It is when physicians are bogged down … when they lack a clear understanding of disease mechanisms, that the deficiencies of the health-care system are most conspicuous. If I were a policy-maker, interested in saving money for health care over the long haul, I would regard it as an act of high prudence to give high priority to a lot more basic research in biologic science.
In 'The Technology of Medicine', The Lives of a Cell: Notes of a Biology Watcher (1974), 41-42.
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It need scarcely be pointed out that with such a mechanism complete isolation of portion of a species should result relatively rapidly in specific differentiation, and one that is not necessarily adaptive. The effective inter­group competition leading to adaptive advance may be between species rather than races. Such isolation is doubtless usually geographic in character at the outset but may be clinched by the development of hybrid sterility. The usual difference of the chromosome complements of related species puts the importance of chromosome aberration as an evolutionary process beyond question, but, as I see it, this importance is not in the character differences which they bring (slight in balanced types), but rather in leading to the sterility of hybrids and thus making permanent the isolation of two groups.
How far do the observations of actual species and their subdivisions conform to this picture? This is naturally too large a subject for more than a few suggestions.
That evolution involves non-adaptive differentiation to a large extent at the subspecies and even the species level is indicated by the kinds of differences by which such groups are actually distinguished by systematics. It is only at the subfamily and family levels that clear-cut adaptive differences become the rule. The principal evolutionary mechanism in the origin of species must thus be an essentially nonadaptive one.
In Proceedings of the Sixth International Congress of Genetics: Ithaca, New York, 1932 (1932) Vol. 1, 363-364.
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Life is an offensive, directed against the repetitious mechanism of the Universe.
In Adventures of Ideas (1933), 102.
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Mathematics is of two kinds, Rigorous and Physical. The former is Narrow: the latter Bold and Broad. To have to stop to formulate rigorous demonstrations would put a stop to most physico-mathematical inquiries. Am I to refuse to eat because I do not fully understand the mechanism of digestion?
As quoted by Charles Melbourne Focken in Dimensional Methods and Their Applications (1953), 17.
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Modern science gives lectures on botany, to show there is no such thing as a flower; on humanity, to show there is no such thing as a man; and on theology, to show there is no such thing as a God. No such thing as a man, but only a mechanism, No such thing as a God, but only a series of forces.
Letter V (1 May 1871) collected in Fors Clavigera: Letters to the Workmen and Labourers of Great Britain (1894), Vol. 1, 61.
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My original decision to devote myself to science was a direct result of the discovery which has never ceased to fill me with enthusiasm since my early youth—the comprehension of the far from obvious fact that the laws of human reasoning coincide with the laws governing the sequences of the impressions we receive from the world about us; that, therefore, pure reasoning can enable man to gain an insight into the mechanism of the latter. In this connection, it is of paramount importance that the outside world is something independent from man, something absolute, and the quest for the laws which apply to this absolute appeared to me as the most sublime scientific pursuit in life.
'A Scientific Autobiography' (1948), in Scientific Autobiography and Other Papers, trans. Frank Gaynor (1950), 13.
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Natural selection is a mechanism for generating an exceedingly high degree of improbability.
This is not a verbatim quote, but it is a summary of Fisher’s idea, as appearing without quotation marks in the words of the editor, Julian Huxley, in J.S. Huxley, A.C. Hardy and E.B. Ford (eds.), Evolution as a Process (1954), 5. The lengthier quote is from Fisher’s full essay 'Retrospect of the Criticisms of the Theory of Natural Selection' which appears in the same book on p.91. See it elsewhere in this site’s collection, as the Fisher quote that begins: “It was Darwin’s chief contribution…”.
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Nature, everywhere the most amazingly and outstandingly remarkable producer of living bodies, being most carefully arranged according to physical, mechanical, and chemical laws, does not give even the smallest hint of its extraordinary and tireless workings and quite clearly points to its work as being alone worthy of a benign and omnipotent God; and it carries this bright quality in all of its traces, in that, just as all of its general mechanisms rejoice, so also do all of their various smallest component parts rejoice in the depth of wisdom, in the height of perfection, and in the lofty arrangement of forms and qualities, which lie far beyond every investigation of the human mind.
'Inaugural Physico-Medical Dissertation on the Blood and the Circulation of the Microcosm' (1749). Trans. Arthur Donovan and Joseph Prentiss, James Hutton's Medical Dissertation (1980), 29.
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Now, a living organism is nothing but a wonderful machine endowed with the most marvellous properties and set going by means of the most complex and delicate mechanism.
From An Introduction to the Study of Experimental Medicine (1865), as translated by Henry Copley Greene (1957), 63.
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One of the major goals when studying specific genetic diseases is to find the primary gene product, which in turn leads to a better understanding of the biochemical basis of the disorder. The bottom line often reads, 'This may lead to effective prenatal diagnosis and eventual eradication of the disease.' But we now have the ironic situation of being able to jump right to the bottom line without reading the rest of the page, that is, without needing to identify the primary gene product or the basic biochemical mechanism of the disease. The technical capability of doing this is now available. Since the degree of departure from our previous approaches and the potential of this procedure are so great, one will not be guilty of hyperbole in calling it the 'New Genetics'.
'Prenatal Diagnosis and the New Genetics', The American Journal of Human Genetics, 1980, 32:3, 453.
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Physical concepts are free creations of the human mind, and are not, however it may seem, uniquely determined by the external world. In our endeavour to understand reality we are somewhat like a man trying to understand the mechanism of a closed watch. He sees the face and the moving hands, even hears its ticking, but he has no way of opening the case. If he is ingenious he may form some picture of a mechanism which could be responsible for all the things he observes, but he may never be quite sure his picture is the only one which could explain his observations. He will never be able to compare his picture with the real mechanism and he cannot even imagine the possibility or the meaning of such a comparison. But he certainly believes that, as his knowledge increases, his picture of reality will become simpler and simpler and will explain a wider and wider range of his sensuous impressions. He may also believe in the existence of the ideal limit of knowledge and that it is approached by the human mind. He may call this ideal limit the objective truth.
Albert Einstein and Leopold Infeld, The Evolution of Physics (1938), 33.
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Reproduction is so primitive and fundamental a function of vital organisms that the mechanism by which it is assured is highly complex and not yet clearly understood. It is not necessarily connected with sex, nor is sex necessarily connected with reproduction.
Psychology of Sex (1933), 7.
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Science doesn’t purvey absolute truth. Science is a mechanism, a way of trying to improve your knowledge of nature. It’s a system for testing your thoughts against the universe, and seeing whether they match.
'Isaac Asimov Speaks' with Bill Moyers in The Humanist (Jan/Feb 1989), 49. Reprinted in Carl Howard Freedman (ed.), Conversations with Isaac Asimov (2005), 143-144. Bill Moyers asked “What’s real knowledge?” Asimov replied, “Well, we can’t be absolutely certain.” He continued answering as in the quote above.
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Science has thus, most unexpectedly, placed in our hands a new power of great but unknown energy. It does not wake the winds from their caverns; nor give wings to water by the urgency of heat; nor drive to exhaustion the muscular power of animals; nor operate by complicated mechanism; nor summon any other form of gravitating force, but, by the simplest means—the mere contact of metallic surfaces of small extent, with feeble chemical agents, a power everywhere diffused through nature, but generally concealed from our senses, is mysteriously evolved, and by circulation in insulated wires, it is still more mysteriously augmented, a thousand and a thousand fold, until it breaks forth with incredible energy.
Comment upon 'The Notice of the Electro-Magnetic Machine of Mr. Thomas Davenport, of Brandon, near Rutland, Vermont, U.S.', The Annals of Electricity, Magnetism, & Chemistry; and Guardian of Experimental Science (1838), 2, 263.
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Science is not a mechanism but a human progress, and not a set of findings but the search for them.
In Science and Human Values (1956), 63.
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Scientists and particularly the professional students of evolution are often accused of a bias toward mechanism or materialism, even though believers in vitalism and in finalism are not lacking among them. Such bias as may exist is inherent in the method of science. The most successful scientific investigation has generally involved treating phenomena as if they were purely materialistic, rejecting any metaphysical hypothesis as long as a physical hypothesis seems possible. The method works. The restriction is necessary because science is confined to physical means of investigation and so it would stultify its own efforts to postulate that its subject is not physical and so not susceptible to its methods.
The Meaning of Evolution: A Study of the History of Life and of its Significance for Man (1949), 127.
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Society is a self-regulating mechanism for preventing the fulfilment of its members.
In The Decline and Fall of Science (1976), 6.
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Sociological researchers maintain a mask of objectivity. But … when students in these movements report facts that contradict the tenets of their group's creed, they are … punished for their heresy. … forcing them “to leave the movement.” A similar mechanism of repression is at work in every scientific discipline that I know.
In 'The Conformity Police', Global Brain: The Evolution of Mass Mind from the Big Bang to the 21st Century (2000), 86.
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Someday someone will write a pathology of experimental physics and bring to light all those swindles which subvert our reason, beguile our judgement and, what is worse, stand in the way of any practical progress. The phenomena must be freed once and for all from their grim torture chamber of empiricism, mechanism, and dogmatism; they must be brought before the jury of man's common sense.
Jeremy Naydler (ed.), Goethe On Science: An Anthology of Goethe's Scientific Writings (1996), 31.
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Suppose [an] imaginary physicist, the student of Niels Bohr, is shown an experiment in which a virus particle enters a bacterial cell and 20 minutes later the bacterial cell is lysed and 100 virus particles are liberated. He will say: “How come, one particle has become 100 particles of the same kind in 20 minutes? That is very interesting. Let us find out how it happens! How does the particle get in to the bacterium? How does it multiply? Does it multiply like a bacterium, growing and dividing, or does it multiply by an entirely different mechanism ? Does it have to be inside the bacterium to do this multiplying, or can we squash the bacterium and have the multiplication go on as before? Is this multiplying a trick of organic chemistry which the organic chemists have not yet discovered ? Let us find out. This is so simple a phenomenon that the answers cannot be hard to find. In a few months we will know. All we have to do is to study how conditions will influence the multiplication. We will do a few experiments at different temperatures, in different media, with different viruses, and we will know. Perhaps we may have to break into the bacteria at intermediate stages between infection and lysis. Anyhow, the experiments only take a few hours each, so the whole problem can not take long to solve.”
[Eight years later] he has not got anywhere in solving the problem he set out to solve. But [he may say to you] “Well, I made a slight mistake. I could not do it in a few months. Perhaps it will take a few decades, and perhaps it will take the help of a few dozen other people. But listen to what I have found, perhaps you will be interested to join me.”
From 'Experiments with Bacterial Viruses (Bacteriophages)', Harvey Lecture (1946), 41, 161-162. As cited in Robert Olby, The Path of the Double Helix: The Discovery of DNA (1974, 1994), 237.
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The [mechanical] bird I have described ought to be able by the help of the wind to rise to a great height, and this will prove to be its safety; since even if… revolutions [of the winds] were to befall it, it would still have time to regain a condition of equilibrium; provided that its various parts have a great power of resistance, so that they can safely withstand the fury and violence of the descent, by the aid of the defenses which I have mentioned; and its joints should be made of strong tanned hide, and sewn with cords of strong raw silk. And let no one encumber himself with iron bands, for these are very soon broken at the joints or else they become worn out, and consequently it is well not to encumber oneself with them.
'Of the Bird’s Movement' from Sul Voio degli Uccelli, 8 [7] r. in Leonardo da Vinci's Notebooks, trans. E. MacCurdy (1906), 153-4.
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The Anatomist attempts to discover the mechanism; the physiologist attempts to detect the influence which each part exercises.
In The Physiology of Common Life (1864), Vol. 2, 79.
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The complexity of contemporary biology has led to an extreme specialization, which has inevitably been followed by a breakdown in communication between disciplines. Partly as a result of this, the members of each specialty tend to feel that their own work is fundamental and that the work of other groups, although sometimes technically ingenious, is trivial or at best only peripheral to an understanding of truly basic problems and issues. There is a familiar resolution to this problem but it is sometimes difficulty to accept emotionally. This is the idea that there are a number of levels of biological integration and that each level offers problems and insights that are unique to it; further, that each level finds its explanations of mechanism in the levels below, and its significances in the levels above it.
From 'Interaction of physiology and behavior under natural conditions', collected in R.I. Bowman (ed.), The Galapagos (1966), 39.
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The future offers very little hope for those who expect that our new mechanical slaves will offer us a world in which we may rest from thinking. Help us they may, but at the cost of supreme demands upon our honesty and our intelligence. The world of the future will be an ever more demanding struggle against the limitations of our intelligence, not a comfortable hammock in which we can lie down to be waited upon by our robot slaves.
In God & Golem, Inc (1964), 73-74.
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The human mechanism is marvelous. But why not—it is the result of three-and-a-half billion years of tinkering.
Epigraph in Isaac Asimov’s Book of Science and Nature Quotations (1988), 12.
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The last word in ignorance is the man who says of an animal or plant: “What good is it?” If the land mechanism as a whole is good, then every part is good, whether we understand it or not.
From 'Conservation' (c.1938), Round River: From the Journals of Aldo Leopold (1953), 141. Collected in The Essential Aldo Leopold: Quotations and Commentaries (1999), 142.
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The laws of physics must provide a mechanism for the universe to come into being.
As restated in Alan Lindsay Mackay, A Dictionary of Scientific Quotations (1991), 260. Compare with P.C.W. Davies, God and the New Physics (1984), 39, for quotation footnoted from J.A. Wheeler, 'Genesis and observership', Foundational Problems in the Special Science (1977), 39.
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The main Business of Natural Philosophy is to argue from Phænomena without feigning Hypotheses, and to deduce Causes from Effects till we come to the very first Cause, which certainly is not mechanical; and not only to unfold the Mechanism of the World, but chiefly to resolve these, and to such like Questions.
From 'Query 31', Opticks (1704, 2nd ed., 1718), 344.
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The persons who have been employed on these problems of applying the properties of matter and the laws of motion to the explanation of the phenomena of the world, and who have brought to them the high and admirable qualities which such an office requires, have justly excited in a very eminent degree the admiration which mankind feels for great intellectual powers. Their names occupy a distinguished place in literary history; and probably there are no scientific reputations of the last century higher, and none more merited, than those earned by great mathematicians who have laboured with such wonderful success in unfolding the mechanism of the heavens; such for instance as D ’Alembert, Clairaut, Euler, Lagrange, Laplace.
In Astronomy and General Physics (1833), Bk. 3, chap. 4, 327.
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The question whether atoms exist or not... belongs rather to metaphysics. In chemistry we have only to decide whether the assumption of atoms is an hypothesis adapted to the explanation of chemical phenomena... whether a further development of the atomic hypothesis promises to advance our knowledge of the mechanism of chemical phenomena... I rather expect that we shall some day find, for what we now call atoms, a mathematico-mechanical explanation, which will render an account of atomic weight, of atomicity, and of numerous other properties of the so-called atoms.
Laboratory (1867), 1, 303.
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The result would inevitably be a state of universal rest and death, if the universe were finite and left to obey existing laws. But it is impossible to conceive a limit to the extent of matter in the universe; and therefore science points rather to an endless progress, through an endless space, of action involving the transformation of potential energy into palpable motion and thence into heat, than to a single finite mechanism, running down like a clock, and stopping for ever.
In 'On the Age of the Sun's Heat' (1862), Popular Lectures and Addresses (1891), Vol. 1, 349-50.
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The results have exhibited one striking feature which has been frequently emphasized, namely that at high pressures all twelve liquids become more nearly like each other. This suggests that it might be useful in developing a theory of liquids to arbitrarily construct a 'perfect liquid' and to discuss its properties. Certainly the conception of a 'perfect gas' has been of great service in the kinetic theory of gases; and the reason is that all actual gases approximate closely to the 'perfect gas.' In the same way, at high pressures all liquids approximate to one and the same thing, which may be called by analogy the 'perfect liquid.' It seems to offer at least a promising line of attack to discuss the properties of this 'perfect liquid,' and then to invent the simplest possible mechanism to explain them.
'Thermodynamic Properties of Twelve Liquids Between 200 and 800 and up to 1200 KGM. Per Sq. Cm.', Memoirs of the American Academy of Arts and Sciences, 1913, 49, 113.
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The results of science, in the form of mechanism, poison gas, and the yellow press, bid fair to lead to the total downfall of our civilization.
In Conway Memorial Lecture (24 Mar 1922) at South Place Institute, published as Free Thought and Official Propaganda (1922), 55.
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The self-regulating mechanism of the market place cannot always be depended upon to produce adequate results in scientific research.
With co-author Byron S. Miller in The Control of Atomic Energy: A Study of Its Social, Economic, and Political Implications (1948), 17.
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The Wegener hypothesis has been so stimulating and has such fundamental implications in geology as to merit respectful and sympathetic interest from every geologist. Some striking arguments in his favor have been advanced, and it would be foolhardy indeed to reject any concept that offers a possible key to the solution of profound problems in the Earth’s history.
Published while geologists remained sceptical of Alfred Wegener’s idea of Continental Drift, Though unconvinced, he published these thoughts suggesting that critics should be at least be open-minded. His patience was proven justified when two decades later, the theory of plate tectonics provided a mechanism for the motion of the continents.
Some Thoughts on the Evidence for Continental Drift (1944).
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The work of a pioneer in science of technique often consists of finding a correct solution, or creating a working mechanism, based on laws that are not yet discovered.
In The Story of the Winged-S: The Autobiography of Igor I. Sikorsky (2011).
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The world is not as it was when it came from its Maker’s hands. It has been modified by many great revolutions, brought about by an inner mechanism of which we very imperfectly comprehend the movements; but of which we gain a glimpse by studying their effects: and their many causes still acting on the surface of our globe with undiminished power, which are changing, and will continue to change it, as long as it shall last.
Letter 1 to William Wordsworth. Quoted in the appendix to W. Wordsworth, A Complete Guide to the Lakes, Comprising Minute Direction for the Tourist, with Mr Wordsworth's Description of the Scenery of the County and Three Letters upon the Geology of the Lake District (1841), 6.
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There is another approach to the extraterrestrial hypothesis of UFO origins. This assessment depends on a large number of factors about which we know little, and a few about which we know literally nothing. I want to make some crude numerical estimate of the probability that we are frequently visited by extraterrestrial beings.
Now, there is a range of hypotheses that can be examined in such a way. Let me give a simple example: Consider the Santa Claus hypothesis, which maintains that, in a period of eight hours or so on December 24-25 of each year, an outsized elf visits one hundred million homes in the United States. This is an interesting and widely discussed hypothesis. Some strong emotions ride on it, and it is argued that at least it does no harm.
We can do some calculations. Suppose that the elf in question spends one second per house. This isn't quite the usual picture—“Ho, Ho, Ho,” and so on—but imagine that he is terribly efficient and very speedy; that would explain why nobody ever sees him very much-only one second per house, after all. With a hundred million houses he has to spend three years just filling stockings. I have assumed he spends no time at all in going from house to house. Even with relativistic reindeer, the time spent in a hundred million houses is three years and not eight hours. This is an example of hypothesis-testing independent of reindeer propulsion mechanisms or debates on the origins of elves. We examine the hypothesis itself, making very straightforward assumptions, and derive a result inconsistent with the hypothesis by many orders of magnitude. We would then suggest that the hypothesis is untenable.
We can make a similar examination, but with greater uncertainty, of the extraterrestrial hypothesis that holds that a wide range of UFOs viewed on the planet Earth are space vehicles from planets of other stars.
The Cosmic Connection: An Extraterrestrial Perspective (1973), 200.
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There is no subject more captivating, more worthy of study, than nature. To understand this great mechanism, to discover the forces which are active, and the laws which govern them, is the highest aim of the intellect of man.
Lecture (20 May 1891) to American Institute of Electrical Engineers, Columbia College, N. Y., 'Experiments With Alternate Currents Of Very High Frequencv And Their Application To Methods Of Artificial Illumination', collected in Nikola Tesla and Thomas Commerford Martin (ed.), The Inventions, Researches and Writings of Nikola Tesla: With Special Reference to His Work in Polyphase Currents and High Potential Lighting (1894), 145.
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Therefore on long pondering this uncertainty of mathematical traditions on the deduction of the motions of the system of the spheres, I began to feel disgusted that no more certain theory of the motions of the mechanisms of the universe, which has been established for us by the best and most systematic craftsman of all, was agreed by the philosophers, who otherwise theorised so minutely with most careful attention to the details of this system. I therefore set myself the task of reading again the books of all philosophers which were available to me, to search out whether anyone had ever believed that the motions of the spheres of the, universe were other than was supposed by those who professed mathematics in the schools.
'To His Holiness Pope Paul III', in Copernicus: On the Revolutions of the Heavenly Spheres (1543), trans. A. M. Duncan (1976), 25.
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To a man of an impatient disposition, like James Gray, it became clear that in view of the very large number of known species many more generations of scientists could be kept occupied as sedate, taxonomic filing clerks by painstaking description and comparison of structures. This sort of existence was not for him; it lacked the excitement of discovery, and was not likely to make the principles or mechanisms underlying the process of evolution any more plausible.
In obituary, 'James Gray, 14 October 1891 - 14 December 1975', Biographical Memoirs of Fellows of the Royal Society (1 Nov 1978), 24.
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To ask what qualities distinguish good from routine scientific research is to address a question that should be of central concern to every scientist. We can make the question more tractable by rephrasing it, “What attributes are shared by the scientific works which have contributed importantly to our understanding of the physical world—in this case the world of living things?” Two of the most widely accepted characteristics of good scientific work are generality of application and originality of conception. . These qualities are easy to point out in the works of others and, of course extremely difficult to achieve in one’s own research. At first hearing novelty and generality appear to be mutually exclusive, but they really are not. They just have different frames of reference. Novelty has a human frame of reference; generality has a biological frame of reference. Consider, for example, Darwinian Natural Selection. It offers a mechanism so widely applicable as to be almost coexistent with reproduction, so universal as to be almost axiomatic, and so innovative that it shook, and continues to shake, man’s perception of causality.
In 'Scientific innovation and creativity: a zoologist’s point of view', American Zoologist (1982), 22, 230.
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To produce a really good biological theory one must try to see through the clutter produced by evolution to the basic mechanisms lying beneath them, realizing that they are likely to be overlaid by other, secondary mechanisms. What seems to physicists to be a hopelessly complicated process may have been what nature found simplest, because nature could only build on what was already there.
In What Mad Pursuit (1990), 139.
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Underneath all the various theories which are only created to be destroyed; underneath all the hypotheses which one century regards as disclosing the secret mechanism and hidden spring of the universe—and which the following century breaks to pieces as children’s toys—may be recognized the slow progress, slow but incessant, of mathematical physics.
Quote translated from 'Les Théories de l’Optique', Revue des Deux Mondes (1 May 1894), Vol. 123, 125; in 'What is Science', compiled by Mrs. H.O. Ward, in J. M. Stoddart (ed.), The New Science Review: A Miscellany of Modern Thought and Discovery (Oct 1894), Vol. 1, No. 2, 173. From the original French, “Sous les théories qui ne s’élèvent que pour être abuttues, sous les hypothèses qu’un siècle contemple comme le mécanisme secret et le ressort caché de l’Univers, et que le siècle suivant brise comme des jouets d’enfant, se poursuit le progrès lent, mais incessant, de la physique mathématique.” Note: in the New Science Review, the author is incorrectly identified as “Duhene.”
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Watson, if I can get a mechanism which will make a current of electricity vary in its intensity, as the air varies in density when a sound is passing through it, I can telegraph any sound, even the sound of speech.
As quoted by Thomas A. Watson, in Exploring Life: The Autobiography of Thomas A. Watson (1926), 62.
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We can see that, the constant in the law of gravitation being fixed, there may be some upper limit to the amount of matter possible; as more and more matter is added in the distant parts, space curves round and ultimately closes; the process of adding more matter must stop, because there is no more space, and we can only return to the region already dealt with. But there seems nothing to prevent a defect of matter, leaving space unclosed. Some mechanism seems to be needed, whereby either gravitation creates matter, or all the matter in the universe conspires to define a law of gravitation.
In Space, Time and Gravitation: An Outline of the General Relativity Theory (1920, 1921), 163.
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We cannot cheat on DNA. We cannot get round photosynthesis. We cannot say I am not going to give a damn about phytoplankton. All these tiny mechanisms provide the preconditions of our planetary life. To say we do not care is to say in the most literal sense that “we choose death.”
In Maurice F. Strong (ed.), Who Speaks For Earth (1973), 31. In Robert Andrews, The Columbia Book of Quotations (1993), 261.
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We have decided to call the entire field of control and communication theory, whether in the machine or in the animal, by the name Cybernetics, which we form from the Greek … for steersman. In choosing this term, we wish to recognize that the first significant paper on feedback mechanisms is an article on governors, which was published by Clerk Maxwell in 1868, and that governor is derived from a Latin corruption … We also wish to refer to the fact that the steering engines of a ship are indeed one of the earliest and best-developed forms of feedback mechanisms.
In Cybernetics (1948), 19.
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We knew that DNA was important. We knew it was an important molecule. And we knew that its shape was likely to be important. But we didn’t realise I think just how important it would be. Put in other words, we didn’t realise that the shape would give us a clue to the replication mechanism. And this turned out to be really an unexpected dividend from finding out what the shape was.
From Transcript of BBC TV program, The Prizewinners (1962).
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We may say that life has borrowed from inanimate processes the same mechanism used in producing these striking structures that are crystals.
‘The Nature of Forces between Large Molecules of Biological Interest’, Nature (1948), 161, 708.
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We need to explore the possibility that homosexual bonding may be a biological mechanism.
In Pamela Weintraub (ed.), 'E. O. Wilson', The Omni Interviews (1984), 225.
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Well, evolution is a theory. It is also a fact. And facts and theories are different things, not rungs in a hierarchy of increasing certainty. Facts are the world’s data. Theories are structures of ideas that explain and interpret facts. Facts do not go away while scientists debate rival theories for explaining them. Einstein’s theory of gravitation replaced Newton’s, but apples did not suspend themselves in mid-air pending the outcome. And human beings evolved from apelike ancestors whether they did so by Darwin’s proposed mechanism or by some other, yet to be discovered … Evolutionists make no claim for perpetual truth, though creationists often do (and then attack us for a style of argument that they themselves favor).
'Evolution as Fact and Theory', in Hen’s Teeth and Horse’s Toes: Further Reflections in Natural History (1983), 254-255.
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What a deep faith in the rationality of the structure of the world and what a longing to understand even a small glimpse of the reason revealed in the world there must have been in Kepler and Newton to enable them to unravel the mechanism of the heavens in long years of lonely work!
'Religion and Science', The New York Times (9 Nov 1930), Sunday Magazine, 1.
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What is found in biology is mechanisms, mechanisms built with chemical components and that are often modified by other, later, mechanisms added to the earlier ones.
In What Mad Pursuit: A Personal View of Scientific Discovery (1988), 138.
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What we call man is a mechanism made up of … uncrystallized matter … all the colloid matter of his mechanism is concentrated in a countless number of small cells. … [T]hese cells [are] dwelling places, communes, a walled town within which are many citizens. ... [T]hese are the units of life and when they pass out into space man as we think we know him is dead, a mere machine from which the crew have left,so to speak. ... [T]hese units are endowed with great intelligence. They have memories, they must be divided into countless thousands of groups, most are workers, there are directing groups. Some are chemists, they manufacture the most complicated chemicals that are secreted by the glands.
Diary and Sundry Observations of Thomas Alva Edison (1948), 203-44. In Mark Seltzer, Serial Killers (1998), 215-6.
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When I entered the field of space physics in 1956, I recall that I fell in with the crowd believing, for example, that electric fields could not exist in the highly conducting plasma of space. It was three years later that I was shamed by S. Chandrasekhar into investigating Alfvén's work objectively. My degree of shock and surprise in finding Alfvén right and his critics wrong can hardly be described. I learned that a cosmic ray acceleration mechanism basically identical to the famous mechanism suggested by Fermi in 1949 had [previously] been put forth by Alfvén.
Quoted in Anthony L. Peratt, 'Dean of the Plasma Dissidents', Washington Times, supplement: The World and I (May 1988), 195.
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When they [radio astronomers] grew weary at their electronic listening posts. When their eyes grew dim with looking at unrevealing dials and studying uneventful graphs, they could step outside their concrete cells and renew their dull spirits in communion with the giant mechanism they commanded, the silent, sensing instrument in which the smallest packets of energy, the smallest waves of matter, were detected in their headlong, eternal flight across the universe. It was the stethoscope with which they took the pulse of the all and noted the birth and death of stars, the probe which, here on an insignificant planet of an undistinguishable star on the edge of its galaxy, they explored the infinite.
The Listeners (1968, 1972), 12.
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When we no longer look at an organic being as a savage looks at a ship, as something wholly beyond his comprehension; when we regard every production of nature as one which has had a long history; when we contemplate every complex structure and instinct as the summing up of many contrivances, each useful to the possessor, in the same way as any great mechanical invention is the summing up of the labour, the experience, the reason, and even the blunders of numerous workmen; when we thus view each organic being, how far more interesting, I speak from experience, does the study of natural history become!
From the Conclusion of Origin of Species by Means of Natural Selection, Or the Preservation of Favoured Races in the Struggle for Life (3rd. ed., 1861), 521.
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When we understand how animals are resistant to chemicals, the mechanisms are all independent of whether its natural or synthetic. And in fact, when you look at natural chemicals, half of those tested come out positive.
Paper to the American Chemical Society, 'Pollution, Pesticides and Cancer Misconceptions.' As cited by Art Drysdale, 'Latest Insider News: Natural vs. Synthetic Chemical Pesticides' (14 Feb 1999), on the mitosyfraudes.org website. Bruce Ames has written a similar sentiment in various other publications.
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With thermodynamics, one can calculate almost everything crudely; with kinetic theory, one can calculate fewer things, but more accurately; and with statistical mechanics, one can calculate almost nothing exactly.
Edward B. Stuart, Alan J. Brainard and Benjamin Gal-Or (eds.), A Critical Review of Thermodynamics (1970), 205.
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You geneticists may know something about the hereditary mechanisms that distinguish a red-eyed from a white-eyed fruit fly but you haven’t the slightest inkling about the hereditary mechanism that distinguishes fruit flies from elephants.
1925, in Corn, Its Origin, Evolution and Improvement by P. C. Mangelsdorf (1974).
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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