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Today in Science History - Quickie Quiz
Who said: “As far as the laws of mathematics refer to reality, they are not certain; and as far as they are certain, they do not refer to reality.”
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Performance Quotes (51 quotes)

Les Leucocytes Et L'esprit De Sacrifice. — Il semble, d'après les recherches de De Bruyne (Phagocytose, 1895) et de ceux qui le citent, que les leucocytes des Lamellibranches — probablement lorsqu'ils ont phagocyté, qu'ils se sont chargés de résidus et de déchets, qu'ils ont, en un mot, accompli leur rôle et bien fait leur devoir — sortent du corps de l'animal et vont mourir dans le milieu ambiant. Ils se sacrifient. Après avoir si bien servi l'organisme par leur activité, ils le servent encore par leur mort en faisant place aux cellules nouvelles, plus jeunes.
N'est-ce pas la parfaite image du désintéressement le plus noble, et n'y a-t-il point là un exemple et un modèle? Il faut s'en inspirer: comme eux, nous sommes les unités d'un grand corps social; comme eux, nous pouvons le servir et envisager la mort avec sérénité, en subordonnant notre conscience individuelle à la conscience collective.
(30 Jan 1896)
Leukocytes and The Spirit Of Sacrifice. - It seems, according to research by De Bruyne (Phagocytosis, 1885) and those who quote it, that leukocytes of Lamellibranches [bivalves] - likely when they have phagocytized [ingested bacteria], as they become residues and waste, they have, in short, performed their role well and done their duty - leave the body of the animal and will die in the environment. They sacrifice themselves. Having so well served the body by their activities, they still serve in their death by making room for new younger cells.
Isn't this the perfect image of the noblest selflessness, and thereby presents an example and a model? It should be inspiring: like them, we are the units of a great social body, like them, we can serve and contemplate death with equanimity, subordinating our individual consciousness to collective consciousness.
In Recueil d'Œuvres de Léo Errera: Botanique Générale (1908), 194. Google translation by Webmaster. Please give feedback if you can improve it.
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Question: Explain how to determine the time of vibration of a given tuning-fork, and state what apparatus you would require for the purpose.
Answer: For this determination I should require an accurate watch beating seconds, and a sensitive ear. I mount the fork on a suitable stand, and then, as the second hand of my watch passes the figure 60 on the dial, I draw the bow neatly across one of its prongs. I wait. I listen intently. The throbbing air particles are receiving the pulsations; the beating prongs are giving up their original force; and slowly yet surely the sound dies away. Still I can hear it, but faintly and with close attention; and now only by pressing the bones of my head against its prongs. Finally the last trace disappears. I look at the time and leave the room, having determined the time of vibration of the common “pitch” fork. This process deteriorates the fork considerably, hence a different operation must be performed on a fork which is only lent.
Genuine student answer* to an Acoustics, Light and Heat paper (1880), Science and Art Department, South Kensington, London, collected by Prof. Oliver Lodge. Quoted in Henry B. Wheatley, Literary Blunders (1893), 176-7, Question 4. (*From a collection in which Answers are not given verbatim et literatim, and some instances may combine several students' blunders.)
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A Dr van’t Hoff of the veterinary college at Utrecht, appears to have no taste for exact chemical investigation. He finds it a less arduous task to mount Pegasus (evidently borrowed from the veterinary school) and to proclaim in his La Chemie dans l’espace how, during his bold fight to the top of the chemical Parnassus, the atoms appeared to him to have grouped themselves together throughout universal space. … I should have taken no notice of this matter had not Wislicenus oddly enough written a preface to the pamphlet, and not by way of a joke but in all seriousness recommended it a worthwhile performance.
'Signs of the Times', Journal fur Praktische Chemie, 15, 473. Trans. W. H. Brock.
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Before an experiment can be performed, it must be planned—the question to nature must be formulated before being posed. Before the result of a measurement can be used, it must be interpreted—nature's answer must be understood properly. These two tasks are those of the theorist, who finds himself always more and more dependent on the tools of abstract mathematics. Of course, this does not mean that the experimenter does not also engage in theoretical deliberations. The foremost classical example of a major achievement produced by such a division of labor is the creation of spectrum analysis by the joint efforts of Robert Bunsen, the experimenter, and Gustav Kirchoff, the theorist. Since then, spectrum analysis has been continually developing and bearing ever richer fruit.
'The Meaning and Limits of Exact Science', Science (30 Sep 1949), 110, No. 2857, 325. Advance reprinting of chapter from book Max Planck, Scientific Autobiography (1949), 110.
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But of this I can assure you that there is not a movement of any body of Men however small whether on Horse-back or on foot, nor an operation or March of any description nor any Service in the field that is not formed upon some mathematical principle, and in the performance of which the knowledge and practical application of the mathematicks will be found not only useful but necessary. The application of the Mathematicks to Gunnery, Fortification, Tactics, the survey and knowledge of formal Castrenantion etc. cannot be acquired without study.
Duke of Wellington to his son Douro (1826). Quoted in A Selection of the Private Correspondence of the First Duke of Wellington (1952), 44.
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But weightier still are the contentment which comes from work well done, the sense of the value of science for its own sake, insatiable curiosity, and, above all, the pleasure of masterly performance and of the chase. These are the effective forces which move the scientist. The first condition for the progress of science is to bring them into play.
from his preface to Claude Bernard's 'Experimental Medicine'
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But when great and ingenious artists behold their so inept performances, not undeservedly do they ridicule the blindness of such men; since sane judgment abhors nothing so much as a picture perpetrated with no technical knowledge, although with plenty of care and diligence. Now the sole reason why painters of this sort are not aware of their own error is that they have not learnt Geometry, without which no one can either be or become an absolute artist; but the blame for this should be laid upon their masters, who are themselves ignorant of this art.
In The Art of Measurement (1525). As quoted in Albrecht Dürer and R.T. Nichol (trans.), 'Preface', Of the Just Shaping of Letters (1965), Book 3, 1-2.
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Engineers apply the theories and principles of science and mathematics to research and develop economical solutions to practical technical problems. Their work is the link between scientific discoveries and commercial applications. Engineers design products, the machinery to build those products, the factories in which those products are made, and the systems that ensure the quality of the product and efficiency of the workforce and manufacturing process. They design, plan, and supervise the construction of buildings, highways, and transit systems. They develop and implement improved ways to extract, process, and use raw materials, such as petroleum and natural gas. They develop new materials that both improve the performance of products, and make implementing advances in technology possible. They harness the power of the sun, the earth, atoms, and electricity for use in supplying the Nation’s power needs, and create millions of products using power. Their knowledge is applied to improving many things, including the quality of health care, the safety of food products, and the efficient operation of financial systems.
Bureau of Labor Statistics, Occupational Outlook Handbook (2000) as quoted in Charles R. Lord. Guide to Information Sources in Engineering (2000), 5. This definition has been revised and expanded over time in different issues of the Handbook.
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Faced with a new mutation in an organism, or a fundamental change in its living conditions, the biologist is frequently in no position whatever to predict its future prospects. He has to wait and see. For instance, the hairy mammoth seems to have been an admirable animal, intelligent and well-accoutered. Now that it is extinct, we try to understand why it failed. I doubt that any biologist thinks he could have predicted that failure. Fitness and survival are by nature estimates of past performance.
In Scientific American (Sep 1958). As cited in '50, 100 & 150 years ago', Scientific American (Sep 2008), 299, No. 3, 14.
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For the religious, passivism [i.e., objects are obedient to the laws of nature] provides a clear role of God as the author of the laws of nature. If the laws of nature are God’s commands for an essentially passive world…, God also has the power to suspend the laws of nature, and so perform miracles.
In The Philosophy of Nature: A Guide to the New Essentialism (2002), 2.
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He attends constantly the Meetings both of ye Society and the Council; noteth the Observables said and done there; digesteth ym in private; takes care to have ym entered in the Journal- and Register-Books; reads over and corrects all entrys; sollicites the performances of taskes recommended and undertaken; writes all Letters abroad and answers the returns made to ym, entertaining a correspondence with at least 30. persons; employs a great deal of time, and takes much pain in inquiring after and satisfying foorain demands about philosophical matters, dispenseth farr and near store of directions and inquiries for the society’s purpose, and sees them well recommended etc.
Description of his duties as Secretary of the Royal Society, in his own words, but in the third person. As quoted from A. Rupert Hall, 'Henry Oldenburg', in Charles Coulston Gillispie (ed.), Dictionary of National Biography (1974), Vol. 10, 201.
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I am credited with being one of the hardest workers and perhaps I am, if thought is the equivalent of labour, for I have devoted to it almost all of my waking hours. But if work is interpreted to be a definite performance in a specified time according to a rigid rule, then I may be the worst of idlers. Every effort under compulsion demands a sacrifice of life-energy. I never paid such a price. On the contrary, I have thrived on my thoughts.
In 'My Early Life', My Inventions: And Other Writings (2016), 1. Originally published in serial form in Part 1, 'My Early Life' in the series of articles, 'My Inventions', Electrical Experimenter magazine (1919).
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I hold every man a debtor to his profession; from the which as men of course do seek to receive countenance and profit, so ought they of duty to endeavour themselves, by way of amends, to be a help and ornament thereunto. This is performed, in some degree, by the honest and liberal practice of a profession; where men shall carry a respect not to descend into any course that is corrupt and unworthy thereof, and preserve themselves free from the abuses wherewith the same profession is noted to be infected: but much more is this performed, if a man be able to visit and strengthen the roots and foundation of the science itself; thereby not only gracing it in reputation and dignity, but also amplifying it in profession and substance.
Opening sentences of Preface, Maxims of Law (1596), in The Works of Francis Bacon: Law tracts. Maxims of the Law (1803), Vol. 4, 10.
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I undertake my scientific research with the confident assumption that the earth follows the laws of nature which God established at creation. … My studies are performed with the confidence that God will not capriciously confound scientific results by “slipping in” a miracle.
Quoted in Lenny Flank, Deception by Design: The Intelligent Design Movement in America (2007), 81. Also seen as cited from Arthur Newell Strahler, Science and Earth History: the Evolution/Creation Controversy (1987), 40-41.
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In many ways the performances of Donald Trump remind me of male chimpanzees and their dominance rituals. In order to impress rivals, males seeking to rise in the dominance hierarchy perform spectacular displays: stamping, slapping the ground, dragging branches, throwing rocks. The more vigorous and imaginative the display, the faster the individual is likely to rise in the hierarchy, and the longer he is likely to maintain that position.
As quoted in magazine article by James Fallows, 'When Donald Meets Hillary', The Atlantic (Oct 2016). The reporter stated “Jane Goodall … told me shortly before Trump won the GOP nomination.”
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In the performance of our duty one feeling should direct us; the case we should consider as our own, and we should ask ourselves, whether, placed under similar circumstances, we should choose to submit to the pain and danger we are about to inflict.
Quoted in Bransby Blake Cooper, The Life of Sir Astley Cooper (1843), Vol. 2, 207.
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In the world of physics we watch a shadowgraph performance of the drama of familiar life. The shadow of my elbow rests on the shadow table as the shadow ink flows over the shadow paper. It is all symbolic, and as a symbol the physicist leaves it. ... The frank realization that physical science is concerned with a world of shadows is one of the most significant of recent advances.
In The Nature of the Physical World (1928, 2005), xiv-xv.
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It is better to teach the child arithmetic and Latin grammar than rhetoric and moral philosophy, because they require exactitude of performance it is made certain that the lesson is mastered, and that power of performance is worth more than knowledge.
In Lecture on 'Education'. Collected in J.E. Cabot (ed.), The Complete Works of Ralph Waldo Emerson: Lectures and Biographical Sketches (1883), 145.
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It is my thesis that the physical functioning of the living individual and the operation of some of the newer communication machines are precisely parallel in their analogous attempts to control entropy through feedback. Both of them have sensory receptors as one stage in their cycle of operation: that is, in both of them there exists a special apparatus for collecting information from the outer world at low energy levels, and for making it available in the operation of the individual or of the machine. In both cases these external messages are not taken neat, but through the internal transforming powers of the apparatus, whether it be alive or dead. The information is then turned into a new form available for the further stages of performance. In both the animal and the machine this performance is made to be effective on the outer world. In both of them, their performed action on the outer world, and not merely their intended aetion, is reported back to the central regulatory apparatus.
In The Human Use of Human Beings: Cybernetics and Society (1954), 26-27.
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It seems to me that the older subjects, classics and mathematics, are strongly to be recommended on the ground of the accuracy with which we can compare the relative performance of the students. In fact the definiteness of these subjects is obvious, and is commonly admitted. There is however another advantage, which I think belongs in general to these subjects, that the examinations can be brought to bear on what is really most valuable in these subjects.
In Conflict of Studies and other Essays (1873), 6-7.
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Just as a tree constitutes a mass arranged in a definite manner, in which, in every single part, in the leaves as in the root, in the trunk as in the blossom, cells are discovered to be the ultimate elements, so is it also with the forms of animal life. Every animal presents itself as a sum of vital unities, every one of which manifests all the characteristics of life. The characteristics and unity of life cannot be limited to anyone particular spot in a highly developed organism (for example, to the brain of man), but are to be found only in the definite, constantly recurring structure, which every individual element displays. Hence it follows that the structural composition of a body of considerable size, a so-called individual, always represents a kind of social arrangement of parts, an arrangement of a social kind, in which a number of individual existences are mutually dependent, but in such a way, that every element has its own special action, and, even though it derive its stimulus to activity from other parts, yet alone effects the actual performance of its duties.
In Lecture I, 'Cells and the Cellular Theory' (1858), Rudolf Virchow and Frank Chance (trans.) ,Cellular Pathology (1860), 13-14.
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No place affords a more striking conviction of the vanity of human hopes than a publick library; for who can see the wall crouded on every side by mighty volumes, the works of laborious meditation, and accurate inquiry, now scarcely known but by the catalogue, and preserved only to encrease the pomp of learning, without considering how many hours have been wasted in vain endeavours, how often imagination has anticipated the praises of futurity, how many statues have risen to the eye of vanity, how many ideal converts have elevated zeal, how often wit has exulted in the eternal infamy of his antagonists, and dogmatism has delighted in the gradual advances of his authority, the immutability of his decrees, and the perpetuity of his power.
Non unquam dedit
Documenta fors majora, quam fragili loco
Starent superbi.

Seneca, Troades, II, 4-6
Insulting chance ne'er call'd with louder voice,
On swelling mortals to be proud no more.
Of the innumerable authors whose performances are thus treasured up in magnificent obscurity, most are forgotten, because they never deserved to be remembered, and owed the honours which they have once obtained, not to judgment or to genius, to labour or to art, but to the prejudice of faction, the stratagem of intrigue, or the servility of adulation.
Nothing is more common than to find men whose works are now totally neglected, mentioned with praises by their contemporaries, as the oracles of their age, and the legislators of science. Curiosity is naturally excited, their volumes after long enquiry are found, but seldom reward the labour of the search. Every period of time has produced these bubbles of artificial fame, which are kept up a while by the breath of fashion and then break at once and are annihilated. The learned often bewail the loss of ancient writers whose characters have survived their works; but perhaps if we could now retrieve them we should find them only the Granvilles, Montagus, Stepneys, and Sheffields of their time, and wonder by what infatuation or caprice they could be raised to notice.
It cannot, however, be denied, that many have sunk into oblivion, whom it were unjust to number with this despicable class. Various kinds of literary fame seem destined to various measures of duration. Some spread into exuberance with a very speedy growth, but soon wither and decay; some rise more slowly, but last long. Parnassus has its flowers of transient fragrance as well as its oaks of towering height, and its laurels of eternal verdure.
The Rambler, Number 106, 23 Mar 1751. In W. J. Bate and Albrecht B. Strauss (eds.), The Rambler (1969), Vol. 2, 200-1.
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Science asks no questions about the ontological pedigree or a priori character of a theory, but is content to judge it by its performance; and it is thus that a knowledge of nature, having all the certainty which the senses are competent to inspire, has been attained—a knowledge which maintains a strict neutrality toward all philosophical systems and concerns itself not with the genesis or a priori grounds of ideas.
Originally published in North American Review (1865). 'The Philosophy of Herbert Spencer,' repr. In Philosophical Writings of Chauncey Wright (1963), p. 8.
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Some see a clear line between genetic enhancement and other ways that people seek improvement in their children and themselves. Genetic manipulation seems somehow worse—more intrusive, more sinister—than other ways of enhancing performance and seeking success. But, morally speaking, the difference is less significant than it seems. Bioengineering gives us reason to question the low-tech, high-pressure child-rearing practices we commonly accept. The hyperparenting familiar in our time represents an anxious excess of mastery and dominion that misses the sense of life as a gift. This draws it disturbingly close to eugenics... Was the old eugenics objectionable only insofar as it was coercive? Or is there something inherently wrong with the resolve to deliberately design our progeny’s traits... But removing coercion does not vindicate eugenics. The problem with eugenics and genetic engineering is that they represent a one-sided triumph of willfulness over giftedness, of dominion over reverence, of molding over beholding.
Michael J. Sandel, 'The Case Against Perfection', The Atlantic Monthly (Apr 2004).
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The activity characteristic of professional engineering is the design of structures, machines, circuits, or processes, or of combinations of these elements into systems or plants and the analysis and prediction of their performance and costs under specified working conditions.
1954
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The analogies between science and art are very good as long as you are talking about the creation and the performance. The creation is certainly very analogous. The aesthetic pleasure of the craftsmanship of performance is also very strong in science.
As quoted in Robert S. Root-Bernstein, Michele M. Root-Bernstein, Sparks of Genius: The Thirteen Thinking Tools of the World's Most Creative People (2013), 11.
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The curiosity remains… to grasp more clearly how the same matter, which in physics and chemistry displays orderly and reproducible and relatively simple properties, arranges itself in the most astounding fashions as soon as it is drawn into the orbit of the living organism. The closer one looks at these performances of matter in living organisms the more impressive the show becomes. The meanest living cell becomes a magic puzzle box full of elaborate and changing molecules.
From 'Life: The Magic Puzzle Box', Transactions of the Connecticut Academy of Arts and Sciences (Dec 1949), 38, 173-190.
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The first effect of the mind growing cultivated is that processes once multiple get to be performed in a single act. Lazarus has called this the progressive “condensation” of thought. ... Steps really sink from sight. An advanced thinker sees the relations of his topics is such masses and so instantaneously that when he comes to explain to younger minds it is often hard ... Bowditch, who translated and annotated Laplace's Méchanique Céleste, said that whenever his author prefaced a proposition by the words “it is evident,” he knew that many hours of hard study lay before him.
In The Principles of Psychology (1918), Vol. 2, 369-370.
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The origin of a science is usually to be sought for not in any systematic treatise, but in the investigation and solution of some particular problem. This is especially the case in the ordinary history of the great improvements in any department of mathematical science. Some problem, mathematical or physical, is proposed, which is found to be insoluble by known methods. This condition of insolubility may arise from one of two causes: Either there exists no machinery powerful enough to effect the required reduction, or the workmen are not sufficiently expert to employ their tools in the performance of an entirely new piece of work. The problem proposed is, however, finally solved, and in its solution some new principle, or new application of old principles, is necessarily introduced. If a principle is brought to light it is soon found that in its application it is not necessarily limited to the particular question which occasioned its discovery, and it is then stated in an abstract form and applied to problems of gradually increasing generality.
Other principles, similar in their nature, are added, and the original principle itself receives such modifications and extensions as are from time to time deemed necessary. The same is true of new applications of old principles; the application is first thought to be merely confined to a particular problem, but it is soon recognized that this problem is but one, and generally a very simple one, out of a large class, to which the same process of investigation and solution are applicable. The result in both of these cases is the same. A time comes when these several problems, solutions, and principles are grouped together and found to produce an entirely new and consistent method; a nomenclature and uniform system of notation is adopted, and the principles of the new method become entitled to rank as a distinct science.
In A Treatise on Projections (1880), Introduction, xi. Published as United States Coast and Geodetic Survey, Treasury Department Document, No. 61.
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The personal adventures of a geologist would form an amusing narrative. He is trudging along, dusty and weather­beaten, with his wallet at his back, and his hammer on his shoulder, and he is taken for a stone-mason travelling in search of work. In mining-countries, he is supposed to be in quest of mines, and receives many tempting offers of shares in the ‘Wheel Dream’, or the ‘Golden Venture’;—he has been watched as a smuggler; it is well if he has not been committed as a vagrant, or apprehended as a spy, for he has been refused admittance to an inn, or has been ushered into the room appropriated to ostlers and postilions. When his fame has spread among the more enlightened part of the community of a district which he has been exploring, and inquiries are made of the peasantry as to the habits and pursuits of the great philosopher who has been among them, and with whom they have become familiar, it is found that the importance attached by him to shells and stones, and such like trumpery, is looked upon as a species of derangement, but they speak with delight of his affability, sprightliness, and good-humour. They respect the strength of his arm, and the weight of his hammer, as they point to marks which he inflicted on the rocks, and they recount with wonder his pedestrian performances, and the voracious appetite with which, at the close of a long day’s work he would devour the coarsest food that was set before him.
In Practical Geology and Mineralogy: With Instructions for the Qualitative Analysis of Minerals (1841), 31-2.
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The philosopher may very justly be delighted with the extent of his views, the artificer with the readiness of his hands, but let the one remember that without mechanical performance, refined speculation is an empty dream, and the other that without theoretical reasoning, dexterity is little more than brute instinct.
In 'The Rambler' (17 Apr 1750), No. 9. Collected in The Rambler (1763), Vol. 1, 48.
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The powers which tend to preserve, and those which tend to change the condition of the earth's surface, are never in equilibrio; the latter are, in all cases, the most powerful, and, in respect of the former, are like living in comparison of dead forces. Hence the law of decay is one which suffers no exception: The elements of all bodies were once loose and unconnected, and to the same state nature has appointed that they should all return... TIME performs the office of integrating the infinitesimal parts of which this progression is made up; it collects them into one sum, and produces from them an amount greater than any that can be assigned.
Illustrations of the Huttonian Theory of the Earth (1802), 116-7.
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The privilege is not allowed even to genius in this world to inspect its own elements, and read its own destiny, and it is perhaps well for mankid that it is so. Could we lift the curtain which hides our future lives, and glance hastily at the misfortunes, the vexations, and the disappointments which await us, we should be discouraged from attempting the performance of even of such deeds as are destined eventually to crown us with honor.
In a book of his reminiscenses, Oliver Hampton Smith, years after his first meeting with Morse, described the inventor - who had by then overcome the initial scepticism over his invention, but instead needed to vigorously defend his exclusive right of property in the magnetic telegraph.
Early Indiana Trials and Sketches (1858), 414.
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The professional standards of conduct for engineers set a very high bar for the professional engineer. Sure, there have been engineering mistakes. Sure, there has been liability ascribed to faulty engineering design. Sure, there are some “bad apples” in the profession. However, considering the scope of the work that engineers have addressed over the last century, their collective performance has been superior.
In 'Engineering Ethics: Only Your Reputation is at Risk' (10 Jul 2015) article on Brigham Young University Wheatley Institution wheatley.byu.edu website. Originally published in Pittsburgh Engineer (Spring 2013).
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The progress of science depends less than is usually believed on the efforts and performance of the individual genius ... many important discoveries have been made by men of ordinary talents, simply because chance had made them, at the proper time and in the proper place and circumstances, recipients of a body of doctrines, facts and techniques that rendered almost inevitable the recognition of an important phenomenon. It is surprising that some historian has not taken malicious pleasure in writing an anthology of 'one discovery' scientists. Many exciting facts have been discovered as a result of loose thinking and unimaginative experimentation, and described in wrappings of empty words. One great discovery does not betoken a great scientist; science now and then selects insignificant standard bearers to display its banners.
Louis Pasteur, Free Lance of Science (1986), 368
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The progress of Science is generally regarded as a kind of clean, rational advance along a straight ascending line; in fact it has followed a zig-zag course, at times almost more bewildering than the evolution of political thought. The history of cosmic theories, in particular, may without exaggeration be called a history of collective obsessions and controlled schizophrenias; and the manner in which some of the most important individual discoveries were arrived at reminds one more of a sleepwalker’s performance than an electronic brain’s.
From 'Preface', in The Sleepwalkers: A History of Man’s Changing Vision of the Universe (1959), 15.
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The real accomplishment of modern science and technology consists in taking ordinary men, informing them narrowly and deeply and then, through appropriate organization, arranging to have their knowledge combined with that of other specialized but equally ordinary men. This dispenses with the need for genius. The resulting performance, though less inspiring, is far more predictable.
In The New Industrial State (1967), 62.
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The responsibility for maintaining the composition of the blood in respect to other constituents devolves largely upon the kidneys. It is no exaggeration to say that the composition of the blood is determined not by what the mouth ingests but by what the kidneys keep; they are the master chemists of our internal environment, which, so to speak, they synthesize in reverse. When, among other duties, they excrete the ashes of our body fires, or remove from the blood the infinite variety of foreign substances which are constantly being absorbed from our indiscriminate gastrointestinal tracts, these excretory operations are incidental to the major task of keeping our internal environment in an ideal, balanced state. Our glands, our muscles, our bones, our tendons, even our brains, are called upon to do only one kind of physiological work, while our kidneys are called upon to perform an innumerable variety of operations. Bones can break, muscles can atrophy, glands can loaf, even the brain can go to sleep, without immediately endangering our survival, but when the kidneys fail to manufacture the proper kind of blood neither bone, muscle, gland nor brain can carry on.
'The Evolution of the Kidney', Lectures on the Kidney (1943), 3.
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The Royal Navy’s unique ability to combat scurvy was said by one naval physician to have doubled its performance and contributed directly to Britain’s eventual defeat of the French and Spanish fleets at Trafalgar in 1805. (It also meant that British sailors became known as “limeys.”)
In A History of the World in 6 Glasses (2005, 2009), 110.
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The very foundation of our science is only an inference; far the whole of it rests an the unprovable assumption that, all through the inferred lapse of time which the inferred performance of inferred geological processes involves, they have been going on in a manner consistent with the laws of nature as we know them now.
'The Value of Outrageous Geological Hypotheses', Science, 1926, 63, 465-466.
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There is nothing distinctively scientific about the hypothetico-deductive process. It is not even distinctively intellectual. It is merely a scientific context for a much more general stratagem that underlies almost all regulative processes or processes of continuous control, namely feedback, the control of performance by the consequences of the act performed. In the hypothetico-deductive scheme the inferences we draw from a hypothesis are, in a sense, its logical output. If they are true, the hypothesis need not be altered, but correction is obligatory if they are false. The continuous feedback from inference to hypothesis is implicit in Whewell’s account of scientific method; he would not have dissented from the view that scientific behaviour can be classified as appropriately under cybernetics as under logic.
Induction and Intuition in Scientific Thought (1969), 54-5.
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These results demonstrate that there is a new polymerase inside the virions of RNA tumour viruses. It is not present in supernatents of normal cells but is present in virions of avian sarcoma and leukemia RNA tumour viruses. The polymerase seems to catalyse the incorporation of deoxyrinonucleotide triphosphates into DNA from an RNA template. Work is being performed to characterize further the reaction and the product. If the present results and Baltimore's results with Rauscher leukemia virus are upheld, they will constitute strong evidence that the DNA proviruses have a DNA genome when they are in virions. This result would have strong implications for theories of viral carcinogenesis and, possibly, for theories of information transfer in other biological systems. [Co-author with American virologist Satoshi Mizutani]
'RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus', Nature (1970), 226, 1213.
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To solve a problem is to create new problems, new knowledge immediately reveals new areas of ignorance, and the need for new experiments. At least, in the field of fast reactions, the experiments do not take very long to perform.
From Nobel Lecture (11 Dec 1967), 'Flash Photolysis and Some of its Applications.' In Nobel Lectures: Chemistry 1963-1970 (1972), 261.
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We've been fighting from the beginning for organic architecture. That is, architecture where the whole is to the part as the part is to the whole, and where the nature of materials, the nature of the purpose, the nature of the entire performance becomes a necessity—architecture of democracy.
Quoted in Aline B. Louchheim, 'Wright Analyzes Architect's Need', New York Times (26 May 1953), 23. Wright was interviewed at age 83 for the opening of a small exhibition of his work at the gallery of the National Institute and the American Academy of Arts and Letters, New York.
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When it was first proposed to establish laboratories at Cambridge, Todhunter, the mathematician, objected that it was unnecessary for students to see experiments performed, since the results could be vouched for by their teachers, all of them of the highest character, and many of them clergymen of the Church of England.
In The Scientific Outlook (1931, 2009), 49.
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When one ponders on the tremendous journey of evolution over the past three billion years or so, the prodigious wealth of structures it has engendered, and the extraordinarily effective teleonomic performances of living beings from bacteria to man, one may well find oneself beginning to doubt again whether all this could conceiveably be the product of an enormous lottery presided over by natural selection, blindly picking the rare winners from among numbers drawn at random. [Nevertheless,] a detailed review of the accumulated modern evidence [shows] that this conception alone is compatible with the facts.
In Jacques Monod and Austryn Wainhouse (trans.), Chance and Necessity: An Essay on the Natural Philosophy of Modern Biology (1971), 138.
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Whereas there is nothing more necessary for promoting the improvement of Philosophical Matters, than the communicating to such, as apply their Studies and Endeavours that way, such things as are discovered or put in practice by others; it is therefore thought fit to employ the Press, as the most proper way to gratifie those, whose engagement in such Studies, and delight in the advancement of Learning and profitable Discoveries, doth entitle them to the knowledge of what this Kingdom, or other parts of the World, do, from time to time, afford as well of the progress of the Studies, Labours, and attempts of the Curious and learned in things of this kind, as of their compleat Discoveries and performances: To the end, that such Productions being clearly and truly communicated, desires after solid and usefull knowledge may be further entertained, ingenious Endeavours and Undertakings cherished, and those, addicted to and conversant in such matters, may be invited and encouraged to search, try, and find out new things, impart their knowledge to one another, and contribute what they can to the Grand design of improving Natural knowledge, and perfecting all Philosophical Arts, and Sciences. All for the Glory of God, the Honour and Advantage of these Kingdoms, and the Universal Good of Mankind.
'Introduction', Philosophical Transactions (1665), 1, 1-2.
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While reading in a textbook of chemistry, … I came across the statement, “nitric acid acts upon copper.” I was getting tired of reading such absurd stuff and I determined to see what this meant. Copper was more or less familiar to me, for copper cents were then in use. I had seen a bottle marked “nitric acid” on a table in the doctor’s office where I was then “doing time.” I did not know its peculiarities, but I was getting on and likely to learn. The spirit of adventure was upon me. Having nitric acid and copper, I had only to learn what the words “act upon” meant … I put one of them [cent] on the table, opened the bottle marked “nitric acid”; poured some of the liquid on the copper; and prepared to make an observation. But what was this wonderful thing which I beheld? The cent was already changed, and it was no small change either. A greenish blue liquid foamed and fumed over the cent and over the table. The air in the neighborhood of the performance became colored dark red. A great colored cloud arose. This was disagreeable and suffocating—how should I stop this? I tried to get rid of the objectionable mess by picking it up and throwing it out of the window, which I had meanwhile opened. I learned another fact—nitric acid not only acts upon copper but it acts upon fingers. The pain led to another unpremeditated experiment. I drew my fingers across my trousers and another fact was discovered. Nitric acid acts upon trousers. Taking everything into consideration, that was the most impressive experiment, and, relatively, probably the most costly experiment I have ever performed.
In F.H. Getman, The Life of Ira Remsen (1940), 9.
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You are urgently warned against allowing yourself to be influenced in any way by theories or by other preconceived notions in the observation of phenomena, the performance of analyses and other determinations.
Laboratory Rules at Munich. Quoted by M. Bergmann, 'Fischer', in Bugge's Das Buch der Grosse Chemiker. Trans. Joseph S. Froton, Contrasts in Scientific Style: Research Groups in the Chemical and Biomedical Sciences (1990), 172.
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You only have to bat 1.000 in two things—flying and heart transplants. Everything else, you can go four in five.
TV programme, SportsCenter (1987). In The Quotable ESPN? (1998), 28.
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Your printers have made but one blunder,
Correct it instanter, and then for the thunder!
We’ll see in a jiffy if this Mr S[pencer]
Has the ghost of a claim to be thought a good fencer.
To my vision his merits have still seemed to dwindle,
Since I have found him allied with the great Dr T[yndall]
While I have, for my part, grown cockier and cockier,
Since I found an ally in yourself, Mr L[ockyer]
And am always, in consequence, thoroughly willin’,
To perform in the pages of Nature's M[acmillan].
Postcard from Tait to Lockyer, editor of Nature, cited by H. Dingle, Nature (1969), 224, 829.
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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- 90 -
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