Bernard: Oh, you're going to zap me with penicillin and pesticides. Spare me that and I'll spare you the bomb and aerosols. But don't confuse progress with perfectibility. A great poet is always timely. A great philosopher is an urgent need. There's no rush for Isaac Newton. We were quite happy with Aristotle's cosmos. Personally, I preferred it. Fifty-five crystal spheres geared to God's crankshaft is my idea of a satisfying universe. I can't think of anything more trivial than the speed of light. Quarks, quasars—big bangs, black holes—who [cares]? How did you people con us out of all that status? All that money? And why are you so pleased with yourselves?
Chloe: Are you against penicillin, Bernard?
Bernard: Don't feed the animals.

Neue Phaenomena zu erklären, dieses macht meine Sorgen aus, und wie froh ist der Forscher, wenn er das so fleissig Gesuche findet, eine Ergötzung wobei das Herz lacht.
To explain new phenomena, that is my task; and how happy is the scientist when he finds what he so diligently sought, a pleasure that gladdens the heart.

A poem in my opinion, is opposed to a work of science by having for its immediate object, pleasure, not truth.

According to Gandhi, the seven sins are wealth without works, pleasure without conscience, knowledge without character, commerce without morality, science without humanity, worship without sacrifice, and politics without principle. Well, Hubert Humphrey may have sinned in the eyes of God, as we all do, but according to those definitions of Gandhi’s, it was Hubert Humphrey without sin.

Art and science coincide insofar as both aim to improve the lives of men and women. The latter normally concerns itself with profit, the former with pleasure. In the coming age, art will fashion our entertainment out of new means of productivity in ways that will simultaneously enhance our profit and maximize our pleasure.
Brecht’s positive vision of theater in the coming age of technology.

But no pursuit at Cambridge was followed with nearly so much eagerness or gave me so much pleasure as collecting beetles. It was the mere passion for collecting, for I did not dissect them, and rarely compared their external characters with published descriptions, but got them named anyhow. I will give a proof of my zeal: one day, on tearing off some old bark, I saw two rare beetles, and seized one in each hand; then I saw a third and new kind, which I could not bear to lose, so that I popped the one which I held in my right hand into my mouth. Alas! it ejected some intensely acrid fluid, which burnt my tongue so that I was forced to spit the beetle out, which was lost, as was the third one.

Every occurrence in Nature is preceded by other occurrences which are its causes, and succeeded by others which are its effects. The human mind is not satisfied with observing and studying any natural occurrence alone, but takes pleasure in connecting every natural fact with what has gone before it, and with what is to come after it.

Facts were never pleasing to him. He acquired them with reluctance and got rid of them with relief. He was never on terms with them until he had stood them on their heads.

I also ask you my friends not to condemn me entirely to the mill of mathematical calculations, and allow me time for philosophical speculations, my only pleasures.

I believe scientists have a duty to share the excitement and pleasure of their work with the general public, and I enjoy the challenge of presenting difficult ideas in an understandable way.

I grow increasingly aware, and in more ways than expected that I am at the center of my own field; and whether it be folly or wisdom, it is a very pleasant feeling.

I have been branded with folly and madness for attempting what the world calls impossibilities, and even from the great engineer, the late James Watt, who said ... that I deserved hanging for bringing into use the high-pressure engine. This has so far been my reward from the public; but should this be all, I shall be satisfied by the great secret pleasure and laudable pride that I feel in my own breast from having been the instrument of bringing forward new principles and new arrangements of boundless value to my country, and however much I may be straitened in pecuniary circumstances, the great honour of being a useful subject can never be taken from me, which far exceeds riches.

I know that I am mortal by nature, and ephemeral; but when I trace at my pleasure the windings to and fro of the heavenly bodies I no longer touch earth with my feet: I stand in the presence of Zeus himself and take my fill of ambrosia, food of the gods.

I see with much pleasure that you are working on a large work on the integral Calculus [ ... ] The reconciliation of the methods which you are planning to make, serves to clarify them mutually, and what they have in common contains very often their true metaphysics; this is why that metaphysics is almost the last thing that one discovers. The spirit arrives at the results as if by instinct; it is only on reflecting upon the route that it and others have followed that it succeeds in generalising the methods and in discovering its metaphysics.

If any student comes to me and says he wants to be useful to mankind and go into research to alleviate human suffering, I advise him to go into charity instead. Research wants real egotists who seek their own pleasure and satisfaction, but find it in solving the puzzles of nature.

If we range through the whole territory of nature, and endeavour to extract from each department the rich stores of knowledge and pleasure they respectively contain, we shall not find a more refined or purer source of amusement, or a more interesting and unfailing subject for recreation, than that which the observation and examination of the structure, affinities, and habits of plants and vegetables, afford.

In its earliest development knowledge is self-sown. Impressions force themselves upon men’s senses whether they will or not, and often against their will. The amount of interest in which these impressions awaken is determined by the coarser pains and pleasures which they carry in their train or by mere curiosity; and reason deals with the materials supplied to it as far as that interest carries it, and no further. Such common knowledge is rather brought than sought; and such ratiocination is little more than the working of a blind intellectual instinct. It is only when the mind passes beyond this condition that it begins to evolve science. When simple curiosity passes into the love of knowledge as such, and the gratification of the æsthetic sense of the beauty of completeness and accuracy seems more desirable that the easy indolence of ignorance; when the finding out of the causes of things becomes a source of joy, and he is accounted happy who is successful in the search, common knowledge passes into what our forefathers called natural history, whence there is but a step to that which used to be termed natural philosophy, and now passes by the name of physical science.
In this final state of knowledge the phenomena of nature are regarded as one continuous series of causes and effects; and the ultimate object of science is to trace out that series, from the term which is nearest to us, to that which is at the farthest limit accessible to our means of investigation.
The course of nature as it is, as it has been, and as it will be, is the object of scientific inquiry; whatever lies beyond, above, or below this is outside science. But the philosopher need not despair at the limitation on his field of labor; in relation to the human mind Nature is boundless; and, though nowhere inaccessible, she is everywhere unfathomable.

In my work I now have the comfortable feeling that I am so to speak on my own ground and territory and almost certainly not competing in an anxious race and that I shall not suddenly read in the literature that someone else had done it all long ago. It is really at this point that the pleasure of research begins, when one is, so to speak, alone with nature and no longer worries about human opinions, views and demands. To put it in a way that is more learned than clear: the philological aspect drops out and only the philosophical remains.

Inventive genius requires pleasurable mental activity as a condition for its vigorous exercise. 'Necessity is the mother of invention' is a silly proverb. 'Necessity is the mother of futile dodges' is much closer to the truth. The basis of growth of modern invention is science, and science is almost wholly the outgrowth of pleasurable intellectual curiosity.

Let me tell you how at one time the famous mathematician Euclid became a physician. It was during a vacation, which I spent in Prague as I most always did, when I was attacked by an illness never before experienced, which manifested itself in chilliness and painful weariness of the whole body. In order to ease my condition I took up Euclid's Elements and read for the first time his doctrine of ratio, which I found treated there in a manner entirely new to me. The ingenuity displayed in Euclid's presentation filled me with such vivid pleasure, that forthwith I felt as well as ever.

Men ought to know that from the brain, and from the brain only, arise our pleasures, joys, laughter and jests, as well as our sorrows, pains, griefs and tears. Through it, in particular, we think, see, hear, and distinguish the ugly from the beautiful, the bad from the good, the pleasant from the unpleasant, in some cases using custom as a test, in others perceiving them from their utility. It is the same thing which makes us mad or delirious, inspires us with dread or fear, whether by night or by day, brings sleeplessness, inopportune mistakes, aimless anxieties, absent-mindedness, and acts that are contrary to habit. These things that we suffer all come from the brain, when it is not healthy, but becomes abnormally hot, cold, moist, or dry, or suffers any other unnatural affection to which it was not accustomed. Madness comes from its moistness.

Nature being capricious and taking pleasure in creating and producing a continuous sucession of lives and forms because she knows that they serve to increase her terrestrial substance, is more ready and swift in her creating than time is in destroying, and therefore she has ordained that many animals shall serve as food one for the other; and as this does not satisfy her desire she sends forth frequently certain noisome and pestilential vapours and continual plagues upon the vast accumulations and herds of animals and especially upon human beings who increase very rapidly because other animals do not feed upon them.

Nature, ... in order to carry out the marvelous operations [that occur] in animals and plants has been pleased to construct their organized bodies with a very large number of machines, which are of necessity made up of extremely minute parts so shaped and situated as to form a marvelous organ, the structure and composition of which are usually invisible to the naked eye without the aid of a microscope. ... Just as Nature deserves praise and admiration for making machines so small, so too the physician who observes them to the best of his ability is worthy of praise, not blame, for he must also correct and repair these machines as well as he can every time they get out of order.

One should guard against preaching to the young man success in the customary sense as the aim in life. ... The most important motive for work in school and in life is pleasure in work, pleasure in its result, and the knowledge of the value of the result to the community.

Science is a wonderful thing, but it has not yet succeeded in maximizing pleasure and minimizing pain, and that's all we asked of it.

So-called extraordinary events always split into two extremes naturalists who have not witnessed them: those who believe blindly and those who do not believe at all. The latter have always in mind the story of the golden goose; if the facts lie slightly beyond the limits of their knowledge, they relegate them immediately to fables. The former have a secret taste for marvels because they seem to expand Nature; they use their imagination with pleasure to find explanations. To remain doubtful is given to naturalists who keep a middle path between the two extremes. They calmly examine facts; they refer to logic for help; they discuss probabilities; they do not scoff at anything, not even errors, because they serve at least the history of the human mind; finally, they report rather than judge; they rarely decide unless they have good evidence.

Speed, is that progress? Anyway, why progress? Why not enjoy what one has? Men have never exhausted present pleasures.

The best that Gauss has given us was likewise an exclusive production. If he had not created his geometry of surfaces, which served Riemann as a basis, it is scarcely conceivable that anyone else would have discovered it. I do not hesitate to confess that to a certain extent a similar pleasure may be found by absorbing ourselves in questions of pure geometry.

The evidence from both approaches, statistical and experimental, does not appear sufficiently significant to me to warrant forsaking the pleasure of smoking. As a matter of fact, if the investigations had been pointed toward some material that I thoroughly dislike, such as parsnips, I still would not feel that evidence of the type presented constituted a reasonable excuse for eliminating the things from my diet. I will still continue to smoke, and if the tobacco companies cease manufacturing their product, I will revert to sweet fern and grape leaves.

The indescribable pleasure—which pales the rest of life's joys—is abundant compensation for the investigator who endures the painful and persevering analytical work that precedes the appearance of the new truth, like the pain of childbirth. It is true to say that nothing for the scientific scholar is comparable to the things that he has discovered. Indeed, it would be difficult to find an investigator willing to exchange the paternity of a scientific conquest for all the gold on earth. And if there are some who look to science as a way of acquiring gold instead of applause from the learned, and the personal satisfaction associated with the very act of discovery, they have chosen the wrong profession.

The largest land animal is the elephant, and it is the nearest to man in intelligence: it understands the language of its country and obeys orders, remembers duties that it has been taught, is pleased by affection and by marks of honour, nay more it possesses virtues rare even in man, honesty, wisdom, justice, also respect for the stars and reverence for the sun and moon.

The mathematician is entirely free, within the limits of his imagination, to construct what worlds he pleases. What he is to imagine is a matter for his own caprice; he is not thereby discovering the fundamental principles of the universe nor becoming acquainted with the ideas of God. If he can find, in experience, sets of entities which obey the same logical scheme as his mathematical entities, then he has applied his mathematics to the external world; he has created a branch of science.

The mere man of pleasure is miserable in old age, and the mere drudge in business is but little better, whereas, natural philosophy, mathematical and mechanical science, are a continual source of tranquil pleasure, and in spite of the gloomy dogmas of priests and of superstition, the study of these things is the true theology; it teaches man to know and admire the Creator, for the principles of science are in the creation, and are unchangeable and of divine origin.

The mere man of pleasure is miserable in old age, and the mere drudge in business is but little better, whereas, natural philosophy, mathematical and mechanical science, are a continual source of tranquil pleasure, and in spite of the gloomy dogmas of priests and of superstition, the study of these things is the true theology; it teaches man to know and admire the Creator, for the principles of science are in the creation, and are unchangeable and of divine origin.

The prize is such an extraordinary honor. It might seem unfair, however, to reward a person for having so much pleasure over the years, asking the maize plant to solve specific problems and then watching its responses.

The real value of science is in the getting, and those who have tasted the pleasure of discovery alone know what science is. A problem solved is dead. A world without problems to be solved would be devoid of science.

The really important questions in human life are hardly touched upon by psychologists. Do liars come to believe their own lies? Is pleasure the same as happiness? Is it better to have loved and lost than never to have loved, or not to be able to love?

There are seven sins in the world: wealth without work, pleasure without conscience, knowledge without character, commerce without morality, science without humanity, worship without sacrifice, and politics without principle.

There is an influence which is getting strong and stronger day by day, which shows itself more and more in all departments of human activity, and influence most fruitful and beneficial—the influence of the artist. It was a happy day for the mass of humanity when the artist felt the desire of becoming a physician, an electrician, an engineer or mechanician or—whatnot—a mathematician or a financier; for it was he who wrought all these wonders and grandeur we are witnessing. It was he who abolished that small, pedantic, narrow-grooved school teaching which made of an aspiring student a galley-slave, and he who allowed freedom in the choice of subject of study according to one's pleasure and inclination, and so facilitated development.

These Disciplines [mathematics] serve to inure and corroborate the Mind to a constant Diligence in Study; to undergo the Trouble of an attentive Meditation, and cheerfully contend with such Difficulties as lie in the Way. They wholly deliver us from a credulous Simplicity, most strongly fortify us against the Vanity of Scepticism, effectually restrain from a rash Presumption, most easily incline us to a due Assent, perfectly subject us to the Government of right Reason, and inspire us with Resolution to wrestle against the unjust Tyranny of false Prejudices. If the Fancy be unstable and fluctuating, it is to be poized by this Ballast, and steadied by this Anchor, if the Wit be blunt it is sharpened upon this Whetstone; if luxuriant it is pared by this Knife; if headstrong it is restrained by this Bridle; and if dull it is rouzed by this Spur. The Steps are guided by no Lamp more clearly through the dark Mazes of Nature, by no Thread more surely through the intricate Labyrinths of Philosophy, nor lastly is the Bottom of Truth sounded more happily by any other Line. I will not mention how plentiful a Stock of Knowledge the Mind is furnished from these, with what wholesome Food it is nourished, and what sincere Pleasure it enjoys. But if I speak farther, I shall neither be the only Person, nor the first, who affirms it; that while the Mind is abstracted and elevated from sensible Matter, distinctly views pure Forms, conceives the Beauty of Ideas, and investigates the Harmony of Proportions; the Manners themselves are sensibly corrected and improved, the Affections composed and rectified, the Fancy calmed and settled, and the Understanding raised and excited to more divine Contemplations. All which I might defend by Authority, and confirm by the Suffrages of the greatest Philosophers.

To a person uninstructed in natural history, his country or sea-side stroll is a walk through a gallery filled with wonderful works of art, nine-tenths of which have their faces turned to the wall. Teach him something of natural history, and you place in his hands a catalogue of those which are worth turning around. Surely our innocent pleasures are not so abundant in this life, that we can afford to despise this or any other source of them.

We called the new [fourth] quark the “charmed quark” because we were pleased, and fascinated by the symmetry it brought to the subnuclear world. “Charm” also means a “a magical device to avert evil,” and in 1970 it was realized that the old three quark theory ran into very serious problems. ... As if by magic the existence of the charmed quark would [solve those problems].

We do not ask for what useful purpose the birds do sing, for song is their pleasure since they were created for singing. Similarly, we ought not to ask why the human mind troubles to fathom the secrets of the heavens ... The diversity of the phenomena of Nature is so great, and the treasures hidden in the heavens so rich, precisely in order that the human mind shall never be lacking in fresh nourishment.

With a thousand joys I would accept a nonacademic job for which industriousness, accuracy, loyalty, and such are sufficient without specialized knowledge, and which would give a comfortable living and sufficient leisure, in order to sacrifice to my gods [mathematical research]. For example, I hope to get the editting of the census, the birth and death lists in local districts, not as a job, but for my pleasure and satisfaction...

[Professor Pauling] confesses that he had harboured the feeling that sooner or later he would be the one to get the DNA structure; and although he was pleased with the double-helix, he ‘rather wished the idea had been his’.