How did I discover saccharin? Well, it was partly by accident and partly by study. I had worked a long time on the compound radicals and substitution products of coal tar... One evening I was so interested in my laboratory that I forgot about my supper till quite late, and then rushed off for a meal without stopping to wash my hands. I sat down, broke a piece of bread, and put it to my lips. It tasted unspeakably sweet. I did not ask why it was so, probably because I thought it was some cake or sweetmeat. I rinsed my mouth with water, and dried my moustache with my napkin, when, to my surprise the napkin tasted sweeter than the bread. Then I was puzzled. I again raised my goblet, and, as fortune would have it, applied my mouth where my fingers had touched it before. The water seemed syrup. It flashed on me that I was the cause of the singular universal sweetness, and I accordingly tasted the end of my thumb, and found it surpassed any confectionery I had ever eaten. I saw the whole thing at once. I had discovered some coal tar substance which out-sugared sugar. I dropped my dinner, and ran back to the laboratory. There, in my excitement, I tasted the contents of every beaker and evaporating dish on the table.

Hubble touches people. When you're looking that far out, you're giving people their place in the universe, it touches people. Science is often visual, so it doesn't need translation. It's like poetry, it touches you.

I can assure you, reader, that in a very few hours, even during the first day, you will learn more natural philosophy about things contained in this book, than you could learn in fifty years by reading the theories and opinions of the ancient philosophers. Enemies of science will scoff at the astrologers: saying, where is the ladder on which they have climbed to heaven, to know the foundation of the stars? But in this respect I am exempt from such scoffing; for in proving my written reason, I satisfy sight, hearing, and touch: for this reason, defamers will have no power over me: as you will see when you come to see me in my little Academy.

I have repeatedly had cause to refer to certain resemblances between the phenomena of irritability in the vegetable kingdom and those of the animal body, thus touching a province of investigation which has hitherto been far too little cultivated. In the last instance, indeed, I might say animal and vegetable life must of necessity agree in all essential points, including the phenomena of irritability also, since it is established that the animal organism is constructed entirely and simply from the properties of these substances that all vital movements both of plants and animals are to be explained.

It is agreed that all sound which is the material of music is of three sorts. First is harmonica, which consists of vocal music; second is organica, which is formed from the breath; third is rhythmica, which receives its numbers from the beat of the fingers. For sound is produced either by the voice, coming through the throat; or by the breath, coming through the trumpet or tibia, for example; or by touch, as in the case of the cithara or anything else that gives a tuneful sound on being struck.

One touch of nature makes the whole world kin.

Somewhere in the arrangement of this world there seems to be a great concern about giving us delight, which shows that, in the universe, over and above the meaning of matter and forces, there is a message conveyed through the magic touch of personality. ...
Is it merely because the rose is round and pink that it gives me more satisfaction than the gold which could buy me the necessities of life, or any number of slaves. ... Somehow we feel that through a rose the language of love reached our hearts.

Tell a man that there are 300 billion stars in the universe, and he'll believe you ... Tell him that a bench has wet paint upon it and he'll have to touch it to be sure.

The appearance of Professor Benjamin Peirce, whose long gray hair, straggling grizzled beard and unusually bright eyes sparkling under a soft felt hat, as he walked briskly but rather ungracefully across the college yard, fitted very well with the opinion current among us that we were looking upon a real live genius, who had a touch of the prophet in his make-up.

The discovery of an interaction among the four hemes made it obvious that they must be touching, but in science what is obvious is not necessarily true. When the structure of hemoglobin was finally solved, the hemes were found to lie in isolated pockets on the surface of the subunits. Without contact between them how could one of them sense whether the others had combined with oxygen? And how could as heterogeneous a collection of chemical agents as protons, chloride ions, carbon dioxide, and diphosphoglycerate influence the oxygen equilibrium curve in a similar way? It did not seem plausible that any of them could bind directly to the hemes or that all of them could bind at any other common site, although there again it turned out we were wrong. To add to the mystery, none of these agents affected the oxygen equilibrium of myoglobin or of isolated subunits of hemoglobin. We now know that all the cooperative effects disappear if the hemoglobin molecule is merely split in half, but this vital clue was missed. Like Agatha Christie, Nature kept it to the last to make the story more exciting. There are two ways out of an impasse in science: to experiment or to think. By temperament, perhaps, I experimented, whereas Jacques Monod thought.

The trained nurse has given nursing the human, or shall we say, the divine touch, and made the hospital desirable for patients with serious ailments regardless of their home advantages.

Through seven figures come sensations for a man; there is hearing for sounds, sight for the visible, nostril for smell, tongue for pleasant or unpleasant tastes, mouth for speech, body for touch, passages outwards and inwards for hot or cold breath. Through these come knowledge or lack of it.

We divorced ourselves from the materials of the earth, the rock, the wood, the iron ore; we looked to new materials which were cooked in vats, long complex derivatives of urine which we called plastic. They had no odor of the living, ... their touch was alien to nature. ... [They proliferated] like the matastases of cancer cells.

We do not ask what hope of gain makes a little bird warble, since we know that it takes delight in singing because it is for that very singing that the bird was made, so there is no need to ask why the human mind undertakes such toil in seeking out these secrets of the heavens. ... And just as other animals, and the human body, are sustained by food and drink, so the very spirit of Man, which is something distinct from Man, is nourished, is increased, and in a sense grows up on this diet of knowledge, and is more like the dead than the living if it is touched by no desire for these things.

[On common water.] Its substance reaches everywhere; it touches the past and prepares the future; it moves under the poles and wanders thinly in the heights of air. It can assume forms of exquisite perfection in a snowflake, or strip the living to a single shining bone cast up by the sea.

[Urbain Jean Joseph] Le Verrier—without leaving his study, without even looking at the sky—had found the unknown planet [Neptune] solely by mathematical calculation, and, as it were, touched it with the tip of his pen!