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Part of a series of articles for National Chemistry Week 2023 on
Unveiling the Surprising Healing Power of Chemistry

Chemical Exfoliants for Skin

Chemical exfoliants have revolutionized skincare, offering an effective and gentle approach to achieving smoother, healthier skin. These products are a prime example of the intricate chemistry behind skincare formulations, providing unexpected benefits in terms of skin rejuvenation and treatment of various skin conditions.

At the core of chemical exfoliants are active ingredients that facilitate the shedding of dead skin cells from the skin’s surface. Alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are among the most commonly used chemical exfoliants. The chemistry of these compounds dictates their ability to dissolve the bonds that hold dead skin cells together, revealing the fresher, more youthful skin beneath.

Alpha hydroxy acids, including glycolic acid (derived from sugar cane) and lactic acid (found in milk), work by targeting the uppermost layer of the epidermis. Their chemistry enables them to gently loosen the bonds between dead skin cells, promoting exfoliation and skin renewal. Glycolic acid, for instance, has the smallest molecular size, allowing it to penetrate the skin effectively and stimulate collagen production.

On the other hand, beta hydroxy acids, with salicylic acid being the most well-known, exhibit unique chemistry that makes them particularly effective for oily and acne-prone skin. Salicylic acid is oil-soluble, allowing it to penetrate sebum-clogged pores, exfoliate from within, and reduce the formation of acne lesions.

The unexpected healing power of chemical exfoliants goes beyond merely promoting smoother skin. These products have demonstrated efficacy in treating a range of skin concerns, including acne, hyperpigmentation, fine lines, and uneven skin texture. By encouraging skin cell turnover, chemical exfoliants can fade dark spots, diminish the appearance of wrinkles, and enhance overall skin tone and texture.

Chemistry also plays a role in the formulation of these exfoliants to ensure their safety and effectiveness. The concentration of active ingredients, pH levels, and the inclusion of soothing and hydrating components are carefully balanced by cosmetic chemists to minimize irritation while maximizing results.

Moreover, the chemistry of skin interaction with these exfoliants differs from person to person. Skin type, sensitivity, and individual tolerances all influence how the chemistry of a chemical exfoliant interacts with one’s skin. This variability underscores the importance of patch testing and gradual introduction of these products into one’s skincare routine.

In conclusion, the chemistry behind chemical exfoliants is a testament to the innovative ways in which science contributes to skincare and skin health. These products, rooted in the chemistry of AHAs and BHAs, offer a gentle yet effective approach to achieving radiant and youthful-looking skin. As research continues to advance, chemistry will play an ongoing role in developing formulations that cater to diverse skin types and concerns, further unlocking the healing potential of chemical exfoliants in skincare.

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Nature bears long with those who wrong her. She is patient under abuse. But when abuse has gone too far, when the time of reckoning finally comes, she is equally slow to be appeased and to turn away her wrath. (1882) -- Nathaniel Egleston, who was writing then about deforestation, but speaks equally well about the danger of climate change today.
Carl Sagan Thumbnail Carl Sagan: In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) ...(more by Sagan)

Albert Einstein: I used to wonder how it comes about that the electron is negative. Negative-positive—these are perfectly symmetric in physics. There is no reason whatever to prefer one to the other. Then why is the electron negative? I thought about this for a long time and at last all I could think was “It won the fight!” ...(more by Einstein)

Richard Feynman: It is the facts that matter, not the proofs. Physics can progress without the proofs, but we can't go on without the facts ... if the facts are right, then the proofs are a matter of playing around with the algebra correctly. ...(more by Feynman)
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