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Home > Category Index for Science Quotations > Category Index B > Category: Biology

Biology Quotes (232 quotes)


...after my first feeling of revulsion had passed, I spent three of the most entertaining and instructive weeks of my life studying the fascinating molds which appeared one by one on the slowly disintegrating mass of horse-dung. Microscopic molds are both very beautiful and absorbingly interesting. The rapid growth of their spores, the way they live on each other, the manner in which the different forms come and go, is so amazing and varied that I believe a man could spend his life and not exhaust the forms or problems contained in one plate of manure.
The World Was My Garden (1938, 1941), 55.
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...the study of butterflies—creatures selected as the types of airiness and frivolity—instead of being despised, will some day be valued as one of the most important branches of Biological science.
From The Naturalist on the River Amazons: A record of Adventures, Habits of Animals, Sketches of Brazilian and Indian life, and Aspects of Nature under the Equator, During Eleven Years of Travel (1864), 413.
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[About a conference on Systematic Biology] Many interesting statements were made that apply directly to the work of taxonomists. In some cases the interest lay in the value of the suggestion and sometimes in the obvious need for rebuttal.
In 'Illogicality in Criticism', Systematic Zoology (Dec 1969), 18, No. 4, 470.
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[Beyond natural history] Other biological sciences take up the study at other levels of organization: dissecting the individual into organs and tissues and seeing how these work together, as in physiology; reaching down still further to the level of cells, as in cytology; and reaching the final biological level with the study of living molecules and their interactions, as in biochemistry. No one of these levels can be considered as more important than any other.
In The Nature of Natural History (1961, 2014), 7.
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[Describing a freshman seminar titled “How the Tabby Cat Got Her Stripes or The Silence of the Genes”:] The big idea we start with is: “How is the genome interpreted, and how are stable decisions that affect gene expression inherited from one cell to the next? This is one of the most competitive areas of molecular biology at the moment, and the students are reading papers that in some instances were published this past year. As a consequence, one of the most common answers I have to give to their questions is, “We just don't know.”
As quoted by Kitta MacPherson in 'Exploring Epigenetics: President Shirley Tilghman in the Classroom,' Princeton University Undergraduate Admission web page accessed 14 Oct 2013.
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[Molecular biology] is concerned particularly with the forms of biological molecules and with the evolution, exploitation and ramification of these forms in the ascent to higher and higher levels of organisation. Molecular biology is predominantly three-dimensional and structural—which does not mean, however, that it is merely a refinement of morphology. It must at the same time inquire into genesis and function.
From Harvey lecture (1951). As cited by John Law in 'The Case of X-ray Protein Crystallography', collected in Gerard Lemaine (ed.), Perspectives on the Emergence of Scientific Disciplines, 1976, 141.
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[Science] is the literature of God written on the stars—the trees—the rocks—and more important because [of] its marked utilitarian character.
Quoted in Allan Peskin, Garfield: A Biography (1978), 57.
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[The] weakness of biological balance studies has aptly been illustrated by comparison with the working of a slot machine. A penny brings forth one package of chewing gum; two pennies bring forth two. Interpreted according to the reasoning of balance physiology, the first observation is an indication of the conversion of copper into gum; the second constitutes proof.
[Co-author with David Rittenberg (1906-70).]
'The Application of Isotopes to the Study of Intermediary Metabolism', Science (1938), 87, 222.
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[Using mice as model systems for genetic engineering in biomedicine, instead of bacterial or yeast systems matters because] this transition will have as big an impact on the future of biology as the shift from printing presses to video technology has had on pop culture. A mouse-based world looks and feels different from one viewed through microorganisms.
Quoted in Michael Schrage, 'Biomedical Researchers Scurry to Make Genetically Altered Mice', San Jose Mercury News (8 Feb 1993), 3D. In Donna Jeanne Haraway and Lynn M. Randolph, [email protected]: Feminism and Technoscience (1996), 98.
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Ac kynde wit cometh
Of alle kynnes syghtes,
Of briddes and of beestes,
Of tastes of truthe and of deceites.

Mother-Wit comes from all kinds of experiences,
Of birds and beasts and of tests both true and false.
In William Langland and B. Thomas Wright (ed.) The Vision and Creed of Piers Ploughman (1842), 235. Modern translation by Terrence Tiller in Piers Plowman (1981, 1999), 123.
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A totally blind process can by definition lead to anything; it can even lead to vision itself.
In Jacques Monod and Austryn Wainhouse (trans.), Chance and Necessity: An Essay on the Natural Philosophy of Modern Biology (1972), 98.
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A biophysicist talks physics to the biologists and biology to the physicists, but when he meets another biophysicist, they just discuss women.
Anonymous
In Alan Lindsay Mackay , A Dictionary of Scientific Quotations (2nd Ed., 1991), 4.
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A cell is regarded as the true biological atom.
The Physiology of Common Life (1860), 297.
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A chemical compound once formed would persist for ever, if no alteration took place in surrounding conditions. But to the student of Life the aspect of nature is reversed. Here, incessant, and, so far as we know, spontaneous change is the rule, rest the exception—the anomaly to be accounted for. Living things have no inertia and tend to no equilibrium.
From Address (22 Jul 1854) delivered at St. Martin’s Hall, published as a pamphlet (1854), 7, and collected in 'Educational Value of Natural History Sciences', Lay Sermons, Addresses, and Reviews (1870), 75.
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A complete survey of life on Earth may appear to be a daunting task. But compared with what has been dared and achieved in high-energy physics, molecular genetics, and other branches of “big science,” it is in the second or third rank.
In 'Edward O. Wilson: The Biological Diversity Crisis: A Challenge to Science', Issues in Science and Technology (Fall 1985), 2, No. 1, 26.
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A sound Physics of the Earth should include all the primary considerations of the earth's atmosphere, of the characteristics and continual changes of the earth's external crust, and finally of the origin and development of living organisms. These considerations naturally divide the physics of the earth into three essential parts, the first being a theory of the atmosphere, or Meteorology, the second, a theory of the earth's external crust, or Hydrogeology, and the third, a theory of living organisms, or Biology.
Hydrogéologie (1802), trans. A. V. Carozzi (1964), 18.
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A strong feeling of adventure is animating those who are working on bacterial viruses, a feeling that they have a small part in the great drive towards a fundamental problem in biology.
From 'Experiments with Bacterial Viruses (Bacteriophages)', Harvey Lecture (1946), 41, 187. As cited in Robert Olby, The Path of the Double Helix: The Discovery of DNA (1974, 1994), 238.
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All that biology tells us about the nature of God is that he has “An inordinate fondness for beetles.”
As stated in George Evelyn Hutchison, 'Homage to Santa Rosalia, or Why Are There So Many Kinds of Animals?', The American Naturalist (1959), 93, 145-159.
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Among the studies to which the [Rockefeller] Foundation is giving support is a series in a relatively new field, which may be called molecular biology, in which delicate modern techniques are being used to investigate ever more minute details of certain life processes.
In 'Molecular Biology', Annual Report of the Rockefeller Foundation (1938), 203-4. Reprinted in a letter to Science (6 Nov 1970), 170, 582.
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Analogy is a wonderful, useful and most important form of thinking, and biology is saturated with it. Nothing is worse than a horrible mass of undigested facts, and facts are indigestible unless there is some rhyme or reason to them. The physicist, with his facts, seeks reason; the biologist seeks something very much like rhyme, and rhyme is a kind of analogy.... This analogizing, this fine sweeping ability to see likenesses in the midst of differences is the great glory of biology, but biologists don't know it.... They have always been so fascinated and overawed by the superior prestige of exact physical science that they feel they have to imitate it.... In its central content, biology is not accurate thinking, but accurate observation and imaginative thinking, with great sweeping generalizations.
In Science is a Sacred Cow (1950), 98-100.
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As soon as we touch the complex processes that go on in a living thing, be it plant or animal, we are at once forced to use the methods of this science [chemistry]. No longer will the microscope, the kymograph, the scalpel avail for the complete solution of the problem. For the further analysis of these phenomena which are in flux and flow, the investigator must associate himself with those who have labored in fields where molecules and atoms, rather than multicellular tissues or even unicellular organisms, are the units of study.
'Experimental and Chemical Studies of the Blood with an Appeal for More Extended Chemical Training for the Biological and Medical Investigator', Science (6 Aug 1915), 42, 176.
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At lunch Francis [Crick] winged into the Eagle to tell everyone within hearing distance that we had found the secret of life.
Purported remark made at The Eagle pub (28 Feb 1953), near the Cavendish Laboratory in Cambridge, to celebrate the fact that they, Crick and Watson, had unravelled the structure of DNA. Stated by James Watson in The Double Helix: A Personal Account of the Discovery of the Structure of DNA (1968, 1998), 197. However Francis Crick, in What Mad Pursuit (1990), 77, writes that was “according to Jim,” but “of that I have no recollection.” Nevertheless, some quote collections report this incident with a direct quote as “We have discovered the secret of life!”
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At the beginning of its existence as a science, biology was forced to take cognizance of the seemingly boundless variety of living things, for no exact study of life phenomena was possible until the apparent chaos of the distinct kinds of organisms had been reduced to a rational system. Systematics and morphology, two predominantly descriptive and observational disciplines, took precedence among biological sciences during the eighteenth and nineteenth centuries. More recently physiology has come to the foreground, accompanied by the introduction of quantitative methods and by a shift from the observationalism of the past to a predominance of experimentation.
In Genetics and the Origin of Species (1937, 1982), 6.
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Biological determinism is, in its essence, a theory of limits. It takes the current status of groups as a measure of where they should and must be ... We inhabit a world of human differences and predilections, but the extrapolation of these facts to theories of rigid limits is ideology.
The Mismeasure of Man (1981), 28-9.
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Biology … is the least self-centered, the least narcissistic of the sciences—the one that, by taking us out of ourselves, leads us to re-establish the link with nature and to shake ourselves free from our spiritual isolation.
In 'Victories and Hopes of Biology', Can Man Be Modified? (1959), 31
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Biology as a discipline would benefit enormously if we could bring together the scientists working at the opposite ends of the biological spectrum. Students of organisms who know natural history have abundant questions to offer the students of molecules and cells. And molecular and cellular biologists with their armory of techniques and special insights have much to offer students of organisms and ecology.
In 'The role of natural history in contemporary biology', BioScience (1986), 36, 328-329.
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Biology can be divided into the study of proximate causes, the study of the physiological sciences (broadly conceived), and into the study of ultimate (evolutionary) causes, the subject of natural history.
The Growth of Biological Thought: Diversity, Evolution and Inheritance (1982), 67.
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Biology cannot go far in its subject without being met by mind.
In 'The Brain Collaborates With Psyche', Man On His Nature: The Gifford Lectures, Edinburgh 1937-8 (1940), 290-291.
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Biology has at least 50 more interesting years.
News summaries 31 Dec 1984. Quoted in James Beasley Simpson, Simpson's Contemporary Quotations (1988), 145
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Biology has become as unthinkable without gene-splicing techniques as sending an explorer into the jungle without a compass.
Magazine interview (1981); one year after becoming the first scientist to make bacteria produce a facsimile of human interferon.
'Shaping Life in the Lab'. In Time (9 Mar 1981).
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Biology has become dissection. A living thing is too complicated to be understood. It must be stripped down like some strange machine, and its parts removed, correlated, enlarged, analysed, and tested to see what they are made of and how they work. The microscope has been followed by the ultramicroscope and all the ingenious instrumentation of modern physics and chemistry. The complexity in structure revealed at one magnification is increased at a higher; the reactions discovered by specialists in one technique amplify without finality the discoveries of others. The biologist, searching into the mystery of life, probes more deeply and studies, of necessity, smaller bits and happenings. So the substance and the ways of the living are broken down, and from the pieces tomes are gathered in encyclopaedic summary; what is known of a cell, or of part of a cell, may fill a volume.
In 'Preface', The Life of Plants (1964, 2002), xiii.
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Biology is a science of three dimensions. The first is the study of each species across all levels of biological organization, molecule to cell to organism to population to ecosystem. The second dimension is the diversity of all species in the biosphere. The third dimension is the history of each species in turn, comprising both its genetic evolution and the environmental change that drove the evolution. Biology, by growing in all three dimensions, is progressing toward unification and will continue to do so.
In 'Systematics and the Future of Biology', Systematics and the Origin of Species: on Ernst Mayr's 100th anniversary, Volume 102, Issues 22-26 (2005), 1.
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Biology is the only science in which multiplication means the same thing as division.
Anonymous
[Note: which is what cells do.]
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Biology occupies a position among the sciences both marginal and central. Marginal because, the living world, constituting only a tiny and very “special” part of the universe, it does not seem likely that the study of living beings will ever uncover general laws applicable outside the biosphere. But if the ultimate aim of the whole of science is indeed, as I believe, to clarify man's relationship to the universe, then biology must be accorded a central position, since of all the disciplines it is the one that endeavours to go most directly to the heart of the problems that must be resolved before that of “human nature” can even be framed in other than metaphysical terms.
In Jacques Monod and Austryn Wainhouse (trans.), Chance and Necessity: An Essay on the Natural Philosophy of Modern Biology (1971), xi.
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Biology today is moving in the direction of chemistry. Much of what is understood in the field is based on the structure of molecules and the properties of molecules in relation to their structure. If you have that basis, then biology isn’t just a collection of disconnected facts.
From interview with Neil A. Campbell, in 'Crossing the Boundaries of Science', BioScience (Dec 1986), 36, No. 11, 737.
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Both biological and cultural diversity are now severely threatened and working for their preservation is a critical task.
The Quark and the Jaguar: Adventure in the Simple and Compex (1994), 374-375.
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But it is precisely mathematics, and the pure science generally, from which the general educated public and independent students have been debarred, and into which they have only rarely attained more than a very meagre insight. The reason of this is twofold. In the first place, the ascendant and consecutive character of mathematical knowledge renders its results absolutely insusceptible of presentation to persons who are unacquainted with what has gone before, and so necessitates on the part of its devotees a thorough and patient exploration of the field from the very beginning, as distinguished from those sciences which may, so to speak, be begun at the end, and which are consequently cultivated with the greatest zeal. The second reason is that, partly through the exigencies of academic instruction, but mainly through the martinet traditions of antiquity and the influence of mediaeval logic-mongers, the great bulk of the elementary text-books of mathematics have unconsciously assumed a very repellant form,—something similar to what is termed in the theory of protective mimicry in biology “the terrifying form.” And it is mainly to this formidableness and touch-me-not character of exterior, concealing withal a harmless body, that the undue neglect of typical mathematical studies is to be attributed.
In Editor’s Preface to Augustus De Morgan and Thomas J. McCormack (ed.), Elementary Illustrations of the Differential and Integral Calculus (1899), v.
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But regular biology, as an "ology," has to be "scientific," and this means in practice that it has to be made dull.... Everything has to be expressed in utterly impersonal terms.
In Science is a Sacred Cow (1950), 108-10.
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Cancer is a biological, not a statistical problem.
Anonymous
'Shoot Out in Marlboro Country', Mother Jones Magazine (Jan 1979), 36.
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Chemistry stands at the pivot of science. On the one hand it deals with biology and provides explanations for the processes of life. On the other hand it mingles with physics and finds explanations for chemical phenomena in the fundamental processes and particles of the universe. Chemistry links the familiar with the fundamental.
In Scientific American Library, Molecules (1987, 2003), 2.
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Clinical science has as good a claim to the name and rights and self-subsistence of a science as any other department of biology.
Address by the President. Transactions of the Clinical Society of London (1870), 3, xxxii.
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Computer science … jobs should be way more interesting than even going to Wall Street or being a lawyer--or, I can argue, than anything but perhaps biology, and there it’s just a tie.
From interview (24 May 2004) in Scientific American (Jun 2004), 45.
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Computer science is no more about computers than astronomy is about telescopes, biology is about microscopes or chemistry is about beakers and test tubes. Science is not about tools. It is about how we use them, and what we find out when we do.
In G. Michael Schneider, Judith L. Gersting, Sara Baase, An invitation to Computer Science: Java version (2000), 2.
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Culture is not a biologically transmitted complex.
In 'The Science of Custom', Patterns of Culture (1934, 2005), 14.
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Darwin was a biological evolutionist, because he was first a uniformitarian geologist. Biology is pre-eminent to-day among the natural sciences, because its younger sister, Geology, gave it the means.
Presidential Address to the Geology Section, Report of the British Association for the Advancement of Science (1892), 696.
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Darwinian evolution is the cornerstone of modern biology. But if we accept Darwin’s mechanism for changes in living things, we must postulate another prebiotic form of evolution, which may be described as chemical evolution.
In 'Cosmochemistry The Earliest Evolution', The Science Teacher (Oct 1983), 50, No. 7, 34.
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Developmental Biology, in capitals, is the wave of the future. The creeping reductionism of biochemistry and molecular biology has taken over the cell and heredity, and looks covetously toward the heights of development and evolution. Recent literature is last year. Ancient literature is a decade ago. The rest is history, doubtfully alive. There is no time and often no opportunity to find and study the work of experimental biologists of 50 or 100 years ago, yet that was a time when the world was fresh.
Developmental biology was a lowercase phrase that graduated about 1950 and had previously lived under the cloak of Experimental Zoology
In obituary by Charles R. Scriver, Biographical Memoirs of Fellows of the Royal Society (Nov 1999), 45, 33.
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Does the evolutionary doctrine clash with religious faith? It does not. It is a blunder to mistake the Holy Scriptures for elementary textbooks of astronomy, geology, biology, and anthropology. Only if symbols are construed to mean what they are not intended to mean can there arise imaginary, insoluble conflicts. ... the blunder leads to blasphemy: the Creator is accused of systematic deceitfulness.
In 'Nothing in Biology Makes Sense Except in the Light of Evolution', The American Biology Teacher (Mar 1973), 125-129.
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During the half-century that has elapsed since the enunciation of the cell-theory by Schleiden and Schwann, in 1838-39, it has became ever more clearly apparent that the key to all ultimate biological problems must, in the last analysis, be sought in the cell. It was the cell-theory that first brought the structure of plants and animals under one point of view by revealing their common plan of organization. It was through the cell-theory that Kolliker and Remak opened the way to an understanding of the nature of embryological development, and the law of genetic continuity lying at the basis of inheritance. It was the cell-­theory again which, in the hands of Virchaw and Max Schultze, inaugurated a new era in the history of physiology and pathology, by showing that all the various functions of the body, in health and in disease, are but the outward expression of cell­-activities. And at a still later day it was through the cell-theory that Hertwig, Fol, Van Beneden, and Strasburger solved the long-standing riddle of the fertilization of the egg, and the mechanism of hereditary transmission. No other biological generalization, save only the theory of organic evolution, has brought so many apparently diverse phenomena under a common point of view or has accomplished more far the unification of knowledge. The cell-theory must therefore be placed beside the evolution-theory as one of the foundation stones of modern biology.
In The Cell in Development and Inheritance (1896), 1.
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Dust consisting of fine fibers of asbestos, which are insoluble and virtually indestructible, may become a public health problem in the near future. At a recent international conference on the biological effects of asbestos sponsored by the New York Academy of Sciences, participants pointed out on the one hand that workers exposed to asbestos dust are prone in later life to develop lung cancer, and on the other hand that the use of this family of fibrous silicate compounds has expanded enormously during the past few decades. A laboratory curiosity 100 years ago, asbestos today is a major component of building materials.
In Scientific American (Sep 1964). As cited in '50, 100 & 150 Years Ago', Scientific American (Dec 2014), 311, No. 6, 98.
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Each of the major sciences has contributed an essential ingredient in our long retreat from an initial belief in our own cosmic importance. Astronomy defined our home as a small planet tucked away in one corner of an average galaxy among millions; biology took away our status as paragons created in the image of God; geology gave us the immensity of time and taught us how little of it our own species has occupied.
…...
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Each species has evolved a special set of solutions to the general problems that all organisms must face. By the fact of its existence, a species demonstrates that its members are able to carry out adequately a series of general functions. … These general functions offer a framework within which one can integrate one’s view of biology and focus one’s research. Such a view helps one to avoid becoming lost in a morass of unstructured detail—even though the ways in which different species perform these functions may differ widely. A few obvious examples will suffice. Organisms must remain functionally integrated. They must obtain materials from their environments, and process and release energy from these materials. … They must differentiate and grow, and they must reproduce. By focusing one’s questions on one or another of these obligatory and universal capacities, one can ensure that one’s research will not be trivial and that it will have some chance of achieving broad general applicability.
In 'Integrative Biology: An Organismic Biologist’s Point of View', Integrative and Comparative Biology (2005), 45, 331.
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Economists use the expression “opportunity costs” for losses incurred through certain choices made over others, including ignorance and inaction. For systematics, or more precisely the neglect of systematics and the biological research dependent upon it, the costs are very high.
In 'Edward O. Wilson: The Biological Diversity Crisis: A Challenge to Science', Issues in Science and Technology (Fall 1985), 2, No. 1, 25.
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Engineering is quite different from science. Scientists try to understand nature. Engineers try to make things that do not exist in nature. Engineers stress invention. To embody an invention the engineer must put his idea in concrete terms, and design something that people can use. That something can be a device, a gadget, a material, a method, a computing program, an innovative experiment, a new solution to a problem, or an improvement on what is existing. Since a design has to be concrete, it must have its geometry, dimensions, and characteristic numbers. Almost all engineers working on new designs find that they do not have all the needed information. Most often, they are limited by insufficient scientific knowledge. Thus they study mathematics, physics, chemistry, biology and mechanics. Often they have to add to the sciences relevant to their profession. Thus engineering sciences are born.
Y.C. Fung and P. Tong, Classical and Computational Solid Mechanics (2001), 1.
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Euclidean mathematics assumes the completeness and invariability of mathematical forms; these forms it describes with appropriate accuracy and enumerates their inherent and related properties with perfect clearness, order, and completeness, that is, Euclidean mathematics operates on forms after the manner that anatomy operates on the dead body and its members. On the other hand, the mathematics of variable magnitudes—function theory or analysis—considers mathematical forms in their genesis. By writing the equation of the parabola, we express its law of generation, the law according to which the variable point moves. The path, produced before the eyes of the student by a point moving in accordance to this law, is the parabola.
If, then, Euclidean mathematics treats space and number forms after the manner in which anatomy treats the dead body, modern mathematics deals, as it were, with the living body, with growing and changing forms, and thus furnishes an insight, not only into nature as she is and appears, but also into nature as she generates and creates,—reveals her transition steps and in so doing creates a mind for and understanding of the laws of becoming. Thus modern mathematics bears the same relation to Euclidean mathematics that physiology or biology … bears to anatomy.
In Die Mathematik die Fackelträgerin einer neuen Zeit (1889), 38. As translated in Robert Édouard Moritz, Memorabilia Mathematica; Or, The Philomath’s Quotation-book (1914), 112-113.
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Even mistaken hypotheses and theories are of use in leading to discoveries. This remark is true in all the sciences. The alchemists founded chemistry by pursuing chimerical problems and theories which are false. In physical science, which is more advanced than biology, we might still cite men of science who make great discoveries by relying on false theories. It seems, indeed, a necessary weakness of our mind to be able to reach truth only across a multitude of errors and obstacles.
An Introduction to the Study of Experimental Medicine (1865, translation 1927, 1957), 170.
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Every rule has its limits, and every concept its ambiguities. Most of all is this true in the science of life, where nothing quite corresponds to our ideas; similar ends are reached by varied means, and no causes are simple.
In Internal Factors in Evolution (1965), 13.
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Everything around us is filled with mystery and magic. I find this no cause for despair, no reason to turn for solace to esoteric formulae or chariots of gods. On the contrary, our inability to find easy answers fills me with a fierce pride in our ambivalent biology … with a constant sense of wonder and delight that we should be part of anything so profound.
In Lifetide: A Biology of the Unconscious (1979), 14.
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For this knowledge of right living, we have sought a new name... . As theology is the science of religious life, and biology the science of [physical] life ... so let Oekology be henceforth the science of [our] normal lives ... the worthiest of all the applied sciences which teaches the principles on which to found... healthy... and happy life.
Quoted in Robert Clarke (ed.), Ellen Swallow: The Woman Who Founded Ecology (1973), 120.
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From the infinitely great down to the infinitely small, all things are subject to [the laws of nature]. The sun and the planets follow the laws discovered by Newton and Laplace, just as the atoms in their combinations follow the laws of chemistry, as living creatures follow the laws of biology. It is only the imperfections of the human mind which multiply the divisions of the sciences, separating astronomy from physics or chemistry, the natural sciences from the social sciences. In essence, science is one. It is none other than the truth.
From Cours d’Economie Politique (1896-97), as given in Archives Internationales d’Histoire des Sciences (1993), Issues 131-133, 67.
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Genetics has always turned out to be much more complicated than it seemed reasonable to imagine. Biology is not like physics. The more we know, the less it seems that there is one final explanation waiting to be discovered.
John Mitchinson and John Lloyd, If Ignorance Is Bliss, Why Aren't There More Happy People?: Smart Quotes for Dumb Times (2009), 275.
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Genetics is the first biological science which got in the position in which physics has been in for many years. One can justifiably speak about such a thing as theoretical mathematical genetics, and experimental genetics, just as in physics. There are some mathematical geniuses who work out what to an ordinary person seems a fantastic kind of theory. This fantastic kind of theory nevertheless leads to experimentally verifiable prediction, which an experimental physicist then has to test the validity of. Since the times of Wright, Haldane, and Fisher, evolutionary genetics has been in a similar position.
Oral history memoir. Columbia University, Oral History Research Office, New York, 1962. Quoted in William B. Provine, Sewall Wright and Evolutionary Biology (1989), 277.
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Genetics is to biology what atomic theory is to physics. Its principle is clear: that inheritance is based on particles and not on fluids. Instead of the essence of each parent mixing, with each child the blend of those who made him, information is passed on as a series of units. The bodies of successive generations transport them through time, so that a long-lost character may emerge in a distant descendant. The genes themselves may be older than the species that bear them.
Almost Like a Whale: The Origin of Species Updated (1999), 115.
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Genetics was, I would say, the first part of biology to become a pretty good theoretical subject, based on the theory of the gene and patterns of inheritance of characteristics.
From interview with Neil A. Campbell, in 'Crossing the Boundaries of Science', BioScience (Dec 1986), 36, No. 11, 738.
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Geology differs from physics, chemistry, and biology in that the possibilities for experiment are limited.
In 'The Scientific Character of Geology', The Journal of Geology (Jul 1961), 69, No. 4, 453.
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Geology has its peculiar difficulties, from which all other sciences are exempt. Questions in chemistry may be settled in the laboratory by experiment. Mathematical and philosophical questions may be discussed, while the materials for discussion are ready furnished by our own intellectual reflections. Plants, animals and minerals, may be arranged in the museum, and all questions relating to their intrinsic principles may be discussed with facility. But the relative positions, the shades of difference, the peculiar complexions, whether continuous or in subordinate beds, are subjects of enquiry in settling the character of rocks, which can be judged of while they are in situ only.
A Geological and Agricultural Survey of the District Adjoining the Erie Canal (1824), 8.
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He that could teach mathematics well, would not be a bad teacher in any of [physics, chemistry, biology or psychology] unless by the accident of total inaptitude for experimental illustration; while the mere experimentalist is likely to fall into the error of missing the essential condition of science as reasoned truth; not to speak of the danger of making the instruction an affair of sensation, glitter, or pyrotechnic show.
In Education as a Science (1879), 298.
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Heavy dependence on direct observation is essential to biology not only because of the complexity of biological phenomena, but because of the intervention of natural selection with its criterion of adequacy rather than perfection. In a system shaped by natural selection it is inevitable that logic will lose its way.
In 'Scientific innovation and creativity: a zoologist’s point of view', American Zoologist (1982), 22, 229.
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Edwin Grant Conklin quote: Heredity is to-day the central problem of biology. This problem may be approached from many sides—tha
Heredity is to-day the central problem of biology. This problem may be approached from many sides—that of the breeder, the experimenter, the statistician, the physiologist, the embryologist, the cytologist—but the mechanism of heredity can be studied best by the investigation of the germ cells and their development.
From Address of the vice-president and chairman of Section F, Zoology, American Association for the Advancement of Science, Chicago Meeting (1907-8). Published in 'The Mechanism of Heredity', Science (17 Jan 1908), 27, No. 691, 89-90.
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Historically, science has pursued a premise that Nature can be understood fully, its future predicted precisely, and its behavior controlled at will. However, emerging knowledge indicates that the nature of Earth and biological systems transcends the limits of science, questioning the premise of knowing, prediction, and control. This knowledge has led to the recognition that, for civilized human survival, technological society has to adapt to the constraints of these systems.
As quoted in Chris Maser, Decision-Making for a Sustainable Environment: A Systemic Approach (2012), 4, citing N. Narasimhan, 'Limitations of Science and Adapting to Nature', Environmental Research Letters (Jul-Sep 2007), 2.
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Humanity, in the course of time, had to endure from the hands of science two great outrages against its naive self-love. The first was when humanity discovered that our earth was not the center of the universe…. The second occurred when biological research robbed man of his apparent superiority under special creation, and rebuked him with his descent from the animal kingdom, and his ineradicable animal nature.
From a series of 28 lectures for laymen, Part Three, 'General Theory of the Neurons', Lecture 18, 'Traumatic Fixation—the Unconscious' collected in Sigmund Freud and G. Stanley Hall (trans.), A General Introduction to Psychoanalysis (1920), 246-247.
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I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
British Medical Bulletin (1965). In Maurice B. Strauss, Familiar Medical Quotations (1968), 653.
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I came to biochemistry through chemistry; I came to chemistry, partly by the labyrinthine routes that I have related, and partly through the youthful romantic notion that the natural sciences had something to do with nature. What I liked about chemistry was its clarity surrounded by darkness; what attracted me, slowly and hesitatingly, to biology was its darkness surrounded by the brightness of the givenness of nature, the holiness of life. And so I have always oscillated between the brightness of reality and the darkness of the unknowable. When Pascal speaks of God in hiding, Deus absconditus, we hear not only the profound existential thinker, but also the great searcher for the reality of the world. I consider this unquenchable resonance as the greatest gift that can be bestowed on a naturalist.
Heraclitean Fire: Sketches from a Life before Nature (1978), 55.
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I cannot think of a single field in biology or medicine in which we can claim genuine understanding, and it seems to me the more we learn about living creatures, especially ourselves, the stranger life becomes.
In 'On Science and Certainty', Discover Magazine (Oct 1980).
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I have always tried to fit knowledge that I acquired into my understanding of the world. … When something comes along that I don’t understand, that I can’t fit in, that bothers me, I think about it, mull over it, and perhaps ultimately do some work with it. That’s perhaps the reason that I’ve been able to make discoveries in molecular biology.
From interview with Neil A. Campbell, in 'Crossing the Boundaries of Science', BioScience (Dec 1986), 36, No. 11, 739.
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I recognize nothing that is not material. In physics, chemistry and biology I see only mechanics. The Universe is nothing but an infinite and complex mechanism. Its complexity is so great that it borders on willfulness, suddenness, and randomness; it gives the illusion of free will possessed by conscious beings.
In Monism of the Universe (1931).
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I think the next [21st] century will be the century of complexity. We have already discovered the basic laws that govern matter and understand all the normal situations. We don’t know how the laws fit together, and what happens under extreme conditions. But I expect we will find a complete unified theory sometime this century. The is no limit to the complexity that we can build using those basic laws.
[Answer to question: Some say that while the twentieth century was the century of physics, we are now entering the century of biology. What do you think of this?]
'"Unified Theory" Is Getting Closer, Hawking Predicts', interview in San Jose Mercury News (23 Jan 2000), 29A. Answer quoted in Ashok Sengupta, Chaos, Nonlinearity, Complexity: The Dynamical Paradigm of Nature (2006), vii. Question included in Hans-Joachim Schellnhuber, Nicholas Stern and Mario Molina , Global Sustainability: a Nobel Cause (2010), 13. Cite from Brent Davis and Dennis J. Sumara, Complexity and Education: Inquiries Into Learning, Teaching, and Research (2006), 171.
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I think we may picture those domains where understanding exists, whether in physics, chemistry, biology, psychology, economics or any other discipline as cultivated valleys in a formidably mountainous country. We may recognise in principle that we all inhabit the same world but in practice we do well to cultivate our own valleys, with an occasional assault on the more accessible foothills, rather than to build roads in a vain attempt at colonisation.
From Inaugural Lecture as Cavendish Professor of Physics, Cambridge, as quoted in Gordon L. Glegg, The Development of Design (1981), 1-2.
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I took biology in high school and didn't like it at all. It was focused on memorization. ... I didn't appreciate that biology also had principles and logic ... [rather than dealing with a] messy thing called life. It just wasn't organized, and I wanted to stick with the nice pristine sciences of chemistry and physics, where everything made sense. I wish I had learned sooner that biology could be fun as well.
Interview (23 May 1998), 'Creating the Code to Life', Academy of Achievement web site.
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I venture to maintain, that, if the general culture obtained in the Faculty of Arts were what it ought to be, the student would have quite as much knowledge of the fundamental principles of Physics, of Chemistry, and of Biology, as he needs, before he commenced his special medical studies. Moreover, I would urge, that a thorough study of Human Physiology is, in itself, an education broader and more comprehensive than much that passes under that name. There is no side of the intellect which it does not call into play, no region of human knowledge into which either its roots, or its branches, do not extend; like the Atlantic between the Old and the New Worlds, its waves wash the shores of the two worlds of matter and of mind; its tributary streams flow from both; through its waters, as yet unfurrowed by the keel of any Columbus, lies the road, if such there be, from the one to the other; far away from that Northwest Passage of mere speculation, in which so many brave souls have been hopelessly frozen up.
'Universities: Actual and Ideal' (1874). In Collected Essays (1893), Vol. 3, 220.
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I would like to start by emphasizing the importance of surfaces. It is at a surface where many of our most interesting and useful phenomena occur. We live for example on the surface of a planet. It is at a surface where the catalysis of chemical reactions occur. It is essentially at a surface of a plant that sunlight is converted to a sugar. In electronics, most if not all active circuit elements involve non-equilibrium phenomena occurring at surfaces. Much of biology is concerned with reactions at a surface.
'Surface properties of semiconductors', Nobel Lecture (11 Dec 1956). In Nobel Lectures, Physics 1942-1962 (1967), 377.
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If history and science have taught us anything, it is that passion and desire are not the same as truth. The human mind evolved to believe in the gods. It did not evolve to believe in biology.
Consilience: The Unity of Knowledge (1998, 1999), 286
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If it were possible to transfer the methods of physical or of biological science directly to the study of man, the transfer would long ago have been made ... We have failed not for lack of hypotheses which equate man with the rest of the universe, but for lack of a hypothesis (short of animism) which provides for the peculiar divergence of man ... Let me now state my belief that the peculiar factor in man which forbids our explaining his actions upon the ordinary plane of biology is a highly specialized and unstable biological complex, and that this factor is none other than language.
Linguistics as a Science (1930), 555.
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If it’s green or wriggles, it’s biology. If it stinks, it’s chemistry. If it doesn’t work, it’s physics or engineering. If it’s green and wiggles and stinks and still doesn’t work, it’s psychology. If it’s incomprehensible, it’s mathematics. If it puts you to sleep, it’s statistics.
Anonymous
In Journal of the South African Institute of Mining and Metallurgy (1978), 79, 97, and additional lines from other sources.
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If the task of scientific methodology is to piece together an account of what scientists actually do, then the testimony of biologists should be heard with specially close attention. Biologists work very close to the frontier between bewilderment and understanding.
Biology is complex, messy and richly various, like real life; it travels faster nowadays than physics or chemistry (which is just as well, since it has so much farther to go), and it travels nearer to the ground. It should therefore give us a specially direct and immediate insight into science in the making.
Induction and Intuition in Scientific Thought (1969), 1.
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In … biological research one must resist the temptation to be deflected by details, to follow the fashion of putting the [dissection] pieces too early under the electron microscope. The magnitude of a scientific revelation is not always paralleled by the degree of magnification employed. It is easier to select the points on which attention should be concentrated once the plan is understood.
In 'Electric Location by Fishes', Scientific American (Mar 1963), 208, No. 3, 50.
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In a sense cosmology contains all subjects because it is the story of everything, including biology, psychology and human history. In that single sense it can be said to contain an explanation also of time's arrow. But this is not what is meant by those who advocate the cosmological explanation of irreversibility. They imply that in some way the time arrow of cosmology imposes its sense on the thermodynamic arrow. I wish to disagree with this view. The explanation assumes that the universe is expanding. While this is current orthodoxy, there is no certainty about it. The red-shifts might be due to quite different causes. For example, when light passes through the expanding clouds of gas it will be red-shifted. A large number of such clouds might one day be invoked to explain these red shifts. It seems an odd procedure to attempt to 'explain' everyday occurrences, such as the diffusion of milk into coffee, by means of theories of the universe which are themselves less firmly established than the phenomena to be explained. Most people believe in explaining one set of things in terms of others about which they are more certain, and the explanation of normal irreversible phenomena in terms of the cosmological expansion is not in this category.
'Thermodynamics, Cosmology) and the Physical Constants', in J. T. Fraser (ed.), The Study of Time III (1973), 117-8.
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In biology, nothing is clear, everything is too complicated, everything is a mess, and just when you think you understand something, you peel off a layer and find deeper complications beneath. Nature is anything but simple.
The Hot Zone
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In early times, when the knowledge of nature was small, little attempt was made to divide science into parts, and men of science did not specialize. Aristotle was a master of all science known in his day, and wrote indifferently treatises on physics or animals. As increasing knowledge made it impossible for any one man to grasp all scientific subjects, lines of division were drawn for convenience of study and of teaching. Besides the broad distinction into physical and biological science, minute subdivisions arose, and, at a certain stage of development, much attention was, given to methods of classification, and much emphasis laid on the results, which were thought to have a significance beyond that of the mere convenience of mankind.
But we have reached the stage when the different streams of knowledge, followed by the different sciences, are coalescing, and the artificial barriers raised by calling those sciences by different names are breaking down. Geology uses the methods and data of physics, chemistry and biology; no one can say whether the science of radioactivity is to be classed as chemistry or physics, or whether sociology is properly grouped with biology or economics. Indeed, it is often just where this coalescence of two subjects occurs, when some connecting channel between them is opened suddenly, that the most striking advances in knowledge take place. The accumulated experience of one department of science, and the special methods which have been developed to deal with its problems, become suddenly available in the domain of another department, and many questions insoluble before may find answers in the new light cast upon them. Such considerations show us that science is in reality one, though we may agree to look on it now from one side and now from another as we approach it from the standpoint of physics, physiology or psychology.
In article 'Science', Encyclopedia Britannica (1911), 402.
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In spite of ignorance, folly and passion, the scientific method has won field after field since the days of Galileo. From mechanics it passed to physics, from physics to biology, from biology to psychology, where it is slowly adapting itself to unfamiliar ground.
from A History of Science and Its Relations with Philosophy and Religion (1929, 4th Ed., 1948), 500.
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Influenced by him, and probably even more so by my brother Theodore a year older than me, I soon became interested in biology and developed a respect for the importance of science and the scientific method.
From biographical sketch in Wilhelm Odelberg (ed.) Les Prix Nobel. The Nobel Prizes 1980, (1981).
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It all began with utter, indeed addictive, fascination with other forms of life. That led me through concern about what humanity is doing to the biology of the planet, to consideration of ecosystems and global cycles. That in turn has led to very practical concerns about how people should relate to nature. Yet the original fascination with jewel-like bits of natural science is always there.
Giving his own reason, in 'Seventy-Five Reasons to Become a Scientist', American Scientist (Sep-Oct 1988), 76, No. 5, 450.
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It is … a sign of the times—though our brothers of physics and chemistry may smile to hear me say so—that biology is now a science in which theories can be devised: theories which lead to predictions and predictions which sometimes turn out to be correct. These facts confirm me in a belief I hold most passionately—that biology is the heir of all the sciences.
From Nobel Banquet speech (10 Dec 1960).
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It is an old saying, abundantly justified, that where sciences meet there growth occurs. It is true moreover to say that in scientific borderlands not only are facts gathered that [are] often new in kind, but it is in these regions that wholly new concepts arise. It is my own faith that just as the older biology from its faithful studies of external forms provided a new concept in the doctrine of evolution, so the new biology is yet fated to furnish entirely new fundamental concepts of science, at which physics and chemistry when concerned with the non-living alone could never arrive.
'Biological Thought and Chemical Thought: A Plea for Unification', Linacre Lecture, Cambridge (6 May 1938), published in Lancet (1938),2, 1204.
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It is easy to make out three areas where scientists will be concentrating their efforts in the coming decades. One is in physics, where leading theorists are striving, with the help of experimentalists, to devise a single mathematical theory that embraces all the basic phenomena of matter and energy. The other two are in biology. Biologists—and the rest of us too—would like to know how the brain works and how a single cell, the fertilized egg cell, develops into an entire organism
Article 'The View From Mars', in Annals of the New York Academy of Sciences: Research Facilities of the Future (1994), 735, 37.
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It is my belief that the basic knowledge that we're providing to the world will have a profound impact on the human condition and the treatments for disease and our view of our place on the biological continuum.
From Text of Remarks on the Completion of the First Survey of the First Survey of the Entire Human Genome Project (26 Jun 2000).
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It is not an easy paper to follow, for the items that require retention throughout the analysis are many, and it is fatal to one's understanding to lose track of any of them. Mastery of this paper, however, can give one the strong feeling of being ableto master anything else [one] might have to wrestle within biology.
Describing the paper 'A Correlation of Cytological and Genetic Crossings-over in Zea mays' published by Barbara McClintock and her student Harriet Creighton in the Proceedings of the National Academy of Sciences (1931).
Classic Papers in Genetics (1959), 156.
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It is nothing short of scandalous that we probably only know one out of every ten species on earth, let alone where they are or, various aspects of their biology, and … unless we really know what there is, and where it is, we’re gonna make some mistakes without even knowing we’ve made them.
From Reith Lecture, 'Biodiversity', on BBC Radio 4 (19 Apr 2000). Transcript and audio on BBC website.
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It is now widely realized that nearly all the “classical” problems of molecular biology have either been solved or will be solved in the next decade. The entry of large numbers of American and other biochemists into the field will ensure that all the chemical details of replication and transcription will be elucidated. Because of this, I have long felt that the future of molecular biology lies in the extension of research to other fields of biology, notably development and the nervous system.
Letter to Max Perua, 5 June 1963. Quoted in William B. Wood (ed.), The Nematode Caenorhabditis Elegans (1988), x-xi.
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It is possible to read books on Natural History with intelligence and profit, and even to make good observations, without a scientific groundwork of biological instruction; and it is possible to arrive at empirical facts of hygiene and medical treatment without any physiological instruction. But in all three cases the absence of a scientific basis will render the knowledge fragmentary and incomplete; and this ought to deter every one from offering an opinion on debatable questions which pass beyond the limit of subjective observations. The psychologist who has not prepared himself by a study of the organism has no more right to be heard on the genesis of the psychical states, or of the relations between body and mind, than one of the laity has a right to be heard on a question of medical treatment.
The Physical Basis of Mind (1877), 4.
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It is probable that the scheme of physics will be enlarged so as to embrace the behaviour of living organisms under the influence of life and mind. Biology and psychology are not alien sciences; their operations are not solely mechanical, nor can they be formulated by physics as it is today; but they belong to a physical universe, and their mode of action ought to be capable of being formulated in terms of an enlarged physics in the future, in which the ether will take a predominant place. On the other hand it may be thought that those entities cannot be brought to book so easily, and that they will always elude our ken. If so, there will be a dualism in the universe, which posterity will find staggering, but that will not alter the facts.
In Past Years: an Autobiography (1932), 350. Quoted in book review, Waldehar Kaempfert, 'Sir Oliver Lodge Stands by the Old Physics', New York Times (21 Feb 1932), BR5.
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It is rare enough that a scientist sheds light on an area which nature has kept secret and then during his lifetime, sees that area illuminate in turn every corner of physiology and medicine. It is rarer still that one man can contribute concurrently almost as much to several other biological fields as well. That meanwhile he [August Krogh] should develop in addition a large school of devoted students who loved the man even more, if possible, than they venerated the scientist, spells the highest form of genius.
Commemorative words presented to the American Physiological Society (1950), describing Eugene Landis, his friend and colleague at Harvard University. As quoted and cited in Bodil Schmidt-Nielsen, August and Marie Krogh: Lives in Science (2013), 4.
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It is the intact and functioning organism on which natural selection operates. Organisms are therefore the central element of concern to the biologist who aspires to a broad and integrated understanding of biology.
From 'Interspecific comparison as a tool for ecological physiologists', collected in M.E. Feder, A.F. Bennett, W.W. Burggren, and R.B. Huey, (eds.), New Directions in Ecological Physiology (1987), 15.
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It just so happens that during the 1950s, the first great age of molecular biology, the English schools of Oxford and particularly of Cambridge produced more than a score of graduates of quite outstanding ability—much more brilliant, inventive, articulate and dialectically skillful than most young scientists; right up in the Jim Watson class. But Watson had one towering advantage over all of them: in addition to being extremely clever he had something important to be clever about.
From the postscript to 'Lucky Jim', New York Review of Books (28 Mar 1968). Also collected in 'Lucky Jim', Pluto’s Republic (1982), 275. Also excerpted in Richard Dawkins (ed.), The Oxford Book of Modern Science Writing (2008), 186.
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It may be that in the practice of religion men have real evidence of the Being of God. If that is so, it is merely fallacious to refuse consideration of this evidence because no similar evidence is forthcoming from the study of physics, astronomy or biology.
In Nature, Man and God: Being the Gifford Lectures Delivered in the University of Glasgow in the Academical Years 1932-1933 and 1933-1934 (1934), 11.
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It might be thought … that evolutionary arguments would play a large part in guiding biological research, but this is far from the case. It is difficult enough to study what is happening now. To figure out exactly what happened in evolution is even more difficult. Thus evolutionary achievements can be used as hints to suggest possible lines of research, but it is highly dangerous to trust them too much. It is all too easy to make mistaken inferences unless the process involved is already very well understood.
In What Mad Pursuit: A Personal View of Scientific Discovery (1988), 138-139.
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It seems a miracle that young children easily learn the language of any environment into which they were born. The generative approach to grammar, pioneered by Chomsky, argues that this is only explicable if certain deep, universal features of this competence are innate characteristics of the human brain. Biologically speaking, this hypothesis of an inheritable capability to learn any language means that it must somehow be encoded in the DNA of our chromosomes. Should this hypothesis one day be verified, then lingusitics would become a branch of biology.
'The Generative Grammar of the Immune System', Nobel Lecture, 8 Dec 1984. In Nobel Lectures: Physiology or Medicine 1981-1990 (1993), 223.
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It was Darwin’s chief contribution, not only to Biology but to the whole of natural science, to have brought to light a process by which contingencies a priori improbable are given, in the process of time, an increasing probability, until it is their non-occurrence, rather than their occurrence, which becomes highly improbable.
From essay 'Retrospect of the Criticisms of the Theory of Natural Selection', reproduced in Julian Huxley, A.C. Hardy, and E.B. Ford (eds.), Evolution as a Process (1954), 91, as cited in Elizabeth Knowles, What They Didn't Say: A Book of Misquotations (2006), 79-80. “Natural selection is a mechanism for generating an exceedingly high degree of improbability,” which is seen more often, is a summary form of Fisher’s idea (not a verbatim quote) written by Julian Huxley, ibid, 5.
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It’s fine if you as an adult want to run around pretending or claiming that you don’t believe in evolution, but if we educate a generation of people who don’t believe in science, that’s a recipe for disaster. … The main idea in all of biology is evolution. To not teach it to our young people is wrong.
Bill Nye
As quoted in Sarah Fecht, 'Science Guy Bill Nye Explains Why Evolution Belongs in Science Education', Popular Mechanics (4 Feb 2011).
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Life is too complicated to permit a complete understanding through the study of whole organisms. Only by simplifying a biological problem—breaking it down into a multitude of individual problems—can you get the answers.
From interview with Neil A. Campbell, in 'Crossing the Boundaries of Science', BioScience (Dec 1986), 36, No. 11, 738.
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Mainstream biology may be suffering from what I call 'Physics envy' in aiming to reduce life to nothing but well known, typically Newtonian principles of physics and chemistry.
'From the Editor's Desk', Frontier Perspectives (1991), 2, 3.
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Many thanks for the sending me the book Biology of the Striped Skunk ... Frankly, I doubt whether I shall read it or not, unless I happen to have some intimate contact with a skunk which may induce me to learn more about him.
Undated letter to a member of the Natural History Survey. In D. S. Tarbell and A. Tarbell, Roger Adams, Scientist and Statesman (1981), 192.
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Marxism is sociobiology without biology … Although Marxism was formulated as the enemy of ignorance and superstition, to the extent that it has become dogmatic it has faltered in that commitment and is now mortally threatened by the discoveries of human sociobiology.
In On Human Nature (1978), 191.
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Metaphysical ghosts cannot be killed, because they cannot be touched; but they may be dispelled by dispelling the twilight in which shadows and solidities are easily confounded. The Vital Principle is an entity of this ghostly kind; and although the daylight has dissipated it, and positive Biology is no longer vexed with its visitations, it nevertheless reappears in another shape in the shadowy region of mystery which surrounds biological and all other questions.
The History of Philosophy from Thales to Comte (1867), lxxxiv.
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Molecular biology is essentially the practice of biochemistry without a license.
Essays on Nucleic Acids (1963), 176.
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Much of the geographical work of the past hundred years... has either explicitly or implicitly taken its inspiration from biology, and in particular Darwin. Many of the original Darwinians, such as Hooker, Wallace, Huxley, Bates, and Darwin himself, were actively concerned with geographical exploration, and it was largely facts of geographical distribution in a spatial setting which provided Darwin with the germ of his theory.
'Darwin's Impact on Geography', Annals of the Association of American Geographers (1966), 56, 683.
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My interest in the biology of tissue and organ transplantation arose from my [WW II] military experience at Valley Forge General Hospital in Pennsylvania … a major plastic surgical center. While there, I spent all my available spare time on the plastic surgical wards which were jammed with hundreds of battle casualties. I enjoyed talking to the patients, helping with dressings, and observing the results of the imaginative reconstructive surgical operations.
As a First Lieutenant with only a nine-month surgical internship, randomly assigned to VFGH to await overseas duty. In Tore Frängsmyr and Jan E. Lindsten (eds.), Nobel Lectures: Physiology Or Medicine: 1981-1990 (1993), 556.
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My many years of work and research as a biological and social anthropologist have made it abundantly clear to me that from an evolutionary and biological standpoint, the female is more advanced and constitutionally more richly endowed than the male.
In The Natural Superiority of Women (1952, 1999), 91.
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My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure.” I was supposed to have said in my molecular biology days. (I believe I was sailing at the time.)
What Mad Pursuit: A Personal View of Scientific Discovery (1988), 150.
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Natural history is not equivalent to biology. Biology is the study of life. Natural history is the study of animals and plants—of organisms. Biology thus includes natural history, and much else besides.
In The Nature of Natural History (1961, 2014), 7.
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No serious student of human behavior denies the potent influence of evolved biology upon our cultural lives. Our struggle is to figure out how biology affects us, not whether it does.
In An Urchin in the Storm: Essays about Books and Ideas (1988, 2010), 152.
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Nothing in biology makes sense except in the light of evolution.
Title of article, 'Nothing in Biology makes Sense except in the Light of Evolution', The American Biology Teacher (Mar 1973), 125. Used earlier, stated in a different word order in 'Biology, Molecular and Organismic', American Zoologist, 1964, 4, 449.
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Nothing makes sense in biology except in the light of evolution.
'Biology, Molecular and Organismic', American Zoologist, 1964, 4, 449. Later, worded slightly differently as an article title, 'Nothing in Biology makes Sense except in the Light of Evolution', The American Biology Teacher (Mar 1973), 125.
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Now Freud may be right or he may be wrong in the place he gives to biology in human fate, but I think we must stop to consider whether this emphasis on biology, whether correct or incorrect, is not so far from being a reactionary idea that it is actually a liberating idea. It proposes to us that culture is not all-powerful. It suggests that there is a residue of human quality beyond the reach of cultural control, and that this residue of human quality, elemental as it may be, serves to bring culture itself under criticism and keeps it from being absolute.
In Freud and the Crisis of our Culture (1955), 48.
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Obviously we biologists should fit our methods to our materials. An interesting response to this challenge has been employed particularly by persons who have entered biology from the physical sciences or who are distressed by the variability in biology; they focus their research on inbred strains of genetically homogeneous laboratory animals from which, to the maximum extent possible, variability has been eliminated. These biologists have changed the nature of the biological system to fit their methods. Such a bold and forthright solution is admirable, but it is not for me. Before I became a professional biologist, I was a boy naturalist, and I prefer a contrasting approach; to change the method to fit the system. This approach requires that one employ procedures which allow direct scientific utilization of the successful long-term evolutionary experiments which are documented by the fascinating diversity and variability of the species of animals which occupy the earth. This is easy to say and hard to do.
In 'Scientific innovation and creativity: a zoologist’s point of view', American Zoologist (1982), 22, 232.
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Of all the Prizes endowed by Alfred Nobel, only one has an ambiguous name—the Prize for Physiology or Medicine. Nobel believed that physiology was an experimental science like physics and chemistry. On the other hand, medicine was an empirical art that would rarely merit a scientific prize. To the contrary, however, many of the advances in biology during the subsequent 85 years were made by people trained in medicine who were attempting to solve medical problems.
In Banquet Speech, 'The Nobel Prize in Physiology or Medicine 1985', on website nobelprize.org. Published in Les Prix Nobel, 1985: Nobel Prizes, Presentations, Biographies and Lectures (1986).
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Of our three principal instruments for interrogating Nature,—observation, experiment, and comparison,—the second plays in biology a quite subordinate part. But while, on the one hand, the extreme complication of causes involved in vital processes renders the application of experiment altogether precarious in its results, on the other hand, the endless variety of organic phenomena offers peculiar facilities for the successful employment of comparison and analogy.
In 'University Reform', Darwinism and Other Essays (1893), 302.
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One can say, looking at the papers in this symposium, that the elucidation of the genetic code is indeed a great achievement. It is, in a sense, the key to molecular biology because it shows how the great polymer languages, the nucleic acid language and the protein language, are linked together.
'The Genetic Code: Yesterday, Today, Tomorrow', Cold Spring Harbour Symposium on Quantitative Biology, 1966, 31, 9.
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One dictionary that I consulted remarks that “natural history” now commonly means the study of animals and plants “in a popular and superficial way,” meaning popular and superficial to be equally damning adjectives. This is related to the current tendency in the biological sciences to label every subdivision of science with a name derived from the Greek. “Ecology” is erudite and profound; while “natural history” is popular and superficial. Though, as far as I can see, both labels apply to just about the same package of goods.
In The Nature of Natural History (1961, 2014), 7.
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One of the grandest generalizations formulated by modern biological science is that of the continuity of life; the protoplasmic activity within each living body now on earth has continued without cessation from the remote beginnings of life on our planet, and from that period until the present no single organism has ever arisen save in the form of a bit of living protoplasm detached from a pre-existing portion; the eternal flame of life once kindled upon this earth has passed from organism to organism, and is still, going on existing and propagating, incarnated within the myriad animal and plant forms of everyday life.
In History of the Human Body (1919), 1.
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One thought [spectra are] marvellous, but it is not possible to make progress there. Just as if you have the wing of a butterfly then certainly it is very regular with the colors and so on, but nobody thought one could get the basis of biology from the coloring of the wing of a butterfly.
Quoted from Interviews (I, 7) in 'The Genesis of the Bohr Atom', J.L. Heilbron and T.S. Kuhn, Historical Studies in the Physical Sciences (1969), 257, reprinted in J. L. Heilbron, Historical Studies in the Theory of Atomic Structure (1981), 195.
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Only a people serving an apprenticeship to nature can be trusted with machines. Only such people will so contrive and control those machines that their products are an enhancement of biological needs, and not a denial of them.
From The Grass Roots of Art: Lectures on the Social Aspects of Art in an Industrial Age (1955), 157. Collected in Herbert Read: Selected Writings: Poetry and Criticism (1964), 357.
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Our remote ancestors tried to interpret nature in terms of anthropomorphic concepts of their own creation and failed. The efforts of our nearer ancestors to interpret nature on engineering lines proved equally inadequate. Nature refused to accommodate herself to either of these man-made moulds. On the other hand, our efforts to interpret nature in terms of the concepts of pure mathematics have, so far, proved brilliantly successful. It would now seem to be beyond dispute that in some way nature is more closely allied to the concepts of pure mathematics than to those of biology or of engineering, and…the mathematical interpretation…fits objective nature incomparably better than the two previously tried.
In The Mysterious Universe (1930, Rev. Ed. 1942), 158.
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Physical science comes nearest to that complete system of exact knowledge which all sciences have before them as an ideal. Some fall far short of it. The physicist who inveighs against the lack of coherence and the indefiniteness of theological theories, will probably speak not much less harshly of the theories of biology and psychology. They also fail to come up to his standard of methodology. On the other side of him stands an even superior being—the pure mathematician—who has no high opinion of the methods of deduction used in physics, and does not hide his disapproval of the laxity of what is accepted as proof in physical science. And yet somehow knowledge grows in all these branches. Wherever a way opens we are impelled to seek by the only methods that can be devised for that particular opening, not over-rating the security of our finding, but conscious that in this activity of mind we are obeying the light that is in our nature.
Swarthmore Lecture (1929) at Friends’ House, London, printed in Science and the Unseen World (1929), 77-78.
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Physics investigates the essential nature of the world, and biology describes a local bump. Psychology, human psychology, describes a bump on the bump.
Theories and Things (1981), 93.
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Physics was always the master-science. The behaviour of matter and energy, which was its theme, underlay all action in the world. In time astronomy, chemistry, geology and even biology became extensions of physics. Moreover, its discoveries found ready application, whether in calculating the tides, creating television or releasing nuclear energy. For better or worse, physics made a noise in the world. But the abiding reason for its special status was that it posed the deepest questions to nature.
In The Key to the Universe: Report on the New Physics (1977), 14.
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Possibly the most pregnant recent development in molecular biology is the realization that the beginnings of life are closely associated with the interactions of proteins and nucleic acids.
'X-ray and Related Studies of the Structure of the Proteins and Nucleic Acids', PhD Thesis, University of Leeds (1939), 63. As quoted in Robert Cecil Olby, The Path to the Double Helix: The Discovery of DNA (1974), 70.
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Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
'On Protein Synthesis', Symposia of the Society for Experimental Biology: The Biological Replication of Macromolecules, 1958, 12, 160.
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Psychology is a part of the science of life or biology. … As the physiologist inquires into the way in which the so-called “functions” of the body are performed, so the psychologist studies the so-called “faculties” of the mind.
In Hume (1879), 50.
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Realizing how often ingenious speculation in the complex biological world has led nowhere and how often the real advances in biology as well as in chemistry, physics and astronomy have kept within the bounds of mechanistic interpretation, we geneticists should rejoice, even with our noses on the grindstone (which means both eyes on the objectives), that we have at command an additional means of testing whatever original ideas pop into our heads.
'The Rise of Genetics', Science (1932), 1969, 264.
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Run the tape again, and let the tiny twig of Homo sapiens expire in Africa. Other hominids may have stood on the threshold of what we know as human possibilities, but many sensible scenarios would never generate our level of mentality. Run the tape again, and this time Neanderthal perishes in Europe and Homo erectus in Asia (as they did in our world). The sole surviving human stock, Homo erectus in Africa, stumbles along for a while, even prospers, but does not speciate and therefore remains stable. A mutated virus then wipes Homo erectus out, or a change in climate reconverts Africa into inhospitable forest. One little twig on the mammalian branch, a lineage with interesting possibilities that were never realized, joins the vast majority of species in extinction. So what? Most possibilities are never realized, and who will ever know the difference? Arguments of this form lead me to the conclusion that biology's most profound insight into human nature, status, and potential lies in the simple phrase, the embodiment of contingency: Homo sapiens is an entity, not a tendency.
Wonderful Life (1989), 320.
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Science is beautiful when it makes simple explanations of phenomena or connections between different observations. Examples include the double helix in biology, and the fundamental equations of physics.
[Answer to question: What are the things you find most beautiful in science?]
'Stephen Hawking: "There is no heaven; it's a fairy story"', interview in newspaper The Guardian (15 May 2011).
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Science is not a system of certain, or -established, statements; nor is it a system which steadily advances towards a state of finality... And our guesses are guided by the unscientific, the metaphysical (though biologically explicable) faith in laws, in regularities which we can uncover—discover. Like Bacon, we might describe our own contemporary science—'the method of reasoning which men now ordinarily apply to nature'—as consisting of 'anticipations, rash and premature' and as 'prejudices'.
The Logic of Scientific Discovery (1959), 278.
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Scientific practice is above all a story-telling practice. ... Biology is inherently historical, and its form of discourse is inherently narrative. ... Biology as a way of knowing the world is kin to Romantic literature, with its discourse about organic form and function. Biology is the fiction appropriate to objects called organisms; biology fashions the facts “discovered” about organic beings.
Primate Visions: Gender, Race and Nature in the World of Modern Science(1989), 4-5.
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Scientists are not robotic inducing machines that infer structures of explanation only from regularities observed in natural phenomena (assuming, as I doubt, that such a style of reasoning could ever achieve success in principle). Scientists are human beings, immersed in culture, and struggling with all the curious tools of inference that mind permits ... Culture can potentiate as well as constrain–as Darwin’s translation of Adam Smith’s laissez-faire economic models into biology as the theory of natural selection. In any case, objective minds do not exist outside culture, so we must make the best of our ineluctable embedding.
…...
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Scientists themselves readily admit that they do not fully understand the consequences of our many-faceted assault upon the interwoven fabric of atmosphere, water, land and life in all its biological diversity. But things could also turn out to be worse than the current scientific best guess. In military affairs, policy has long been based on the dictum that we should be prepared for the worst case. Why should it be so different when the security is that of the planet and our long-term future?
Speech, 'Global Security Lecture' at Cambridge University (28 Apr 1993).
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She [Nettie Stevens] was a trained expert in the modern sense—in the sense in which biology has ceased to be a playground for the amateur and a plaything for the mystic.
In obituary, 'The Scientific Work of Miss N.M. Steves', Science (11 Oct 1912), 36, No. 928, 470.
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Society increasingly has neglected the substructure of biology, to its own peril.
In Pamela Weintraub (ed.), 'E. O. Wilson', The Omni Interviews (1984), 233.
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Sociobiology is not just any statement that biology, genetics, and evolutionary theory have something to do with human behavior. Sociobiology is a specific theory about the nature of genetic and evolutionary input into human behavior. It rests upon the view that natural selection is a virtually omnipotent architect, constructing organisms part by part as best solutions to problems of life in local environments. It fragments organisms into “traits,” explains their existence as a set of best solutions, and argues that each trait is a product of natural selection operating “for” the form or behavior in question. Applied to humans, it must view specific behaviors (not just general potentials) as adaptations built by natural selection and rooted in genetic determinants, for natural selection is a theory of genetic change. Thus, we are presented with unproved and unprovable speculations about the adaptive and genetic basis of specific human behaviors: why some (or all) people are aggressive, xenophobic, religious, acquisitive, or homosexual.
In Hen's Teeth and Horses Toes (1983, 2010), 242-243.
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Sometimes I wonder whether there is any such thing as biology. The word was invented rather late—in 1809—and other words like botany, zoology, physiology, anatomy, have much longer histories and in general cover more coherent and unified subject matters. … I would like to see the words removed from dictionaries and college catalogues. I think they do more harm than good because they separate things that should not be separated…
In The Forest and the Sea (1960), 6-7.
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Such biological ideas as the “survival of the fittest,” whatever their doubtful value in natural science, are utterly useless in attempting to understand society … The life of a man in society, while it is incidentally a biological fact, has characteristics that are not reducible to biology and must be explained in the distinctive terms of a cultural analysis … the physical well-being of men is a result of their social organization and not vice versa … Social improvement is a product of advances in technology and social organization, not of breeding or selective elimination … Judgments as to the value of competition between men or enterprises or nations must be based upon social and not allegedly biological consequences; and … there is nothing in nature or a naturalistic philosophy of life to make impossible the acceptance of moral sanctions that can be employed for the common good.
Social Darwinism in American Thought 1860-1915 (1945), 176.
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Teleology is a lady without whom no biologist can live. Yet he is ashamed to show himself with her in public.
Quoted in W.I.B. Beveridge, The Art of Scientific Investigation (1950), 62.
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That the fundamental aspects of heredity should have turned out to be so extraordinarily simple supports us in the hope that nature may, after all, be entirely approachable. Her much-advertised inscrutability has once more been found to be an illusion due to our ignorance. This is encouraging, for, if the world in which we live were as complicated as some of our friends would have us believe we might well despair that biology could ever become an exact science.
The Physical Basis of Heredity (1919), 15.
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The “control of nature” is a phrase conceived in arrogance, born of the Neanderthal age of biology and the convenience of man.
In Silent Spring (1962), 297.
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The advances of biology during the past 20 years have been breathtaking, particularly in cracking the mystery of heredity. Nevertheless, the greatest and most difficult problems still lie ahead. The discoveries of the 1970‘s about the chemical roots of memory in nerve cells or the basis of learning, about the complex behavior of man and animals, the nature of growth, development, disease and aging will be at least as fundamental and spectacular as those of the recent past.
As quoted in 'H. Bentley Glass', New York Times (12 Jan 1970), 96.
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The attempted synthesis of paleontology and genetics, an essential part of the present study, may be particularly surprising and possibly hazardous. Not long ago, paleontologists felt that a geneticist was a person who shut himself in a room, pulled down the shades, watched small flies disporting themselves in milk bottles, and thought that he was studying nature. A pursuit so removed from the realities of life, they said, had no significance for the true biologist. On the other hand, the geneticists said that paleontology had no further contributions to make to biology, that its only point had been the completed demonstration of the truth of evolution, and that it was a subject too purely descriptive to merit the name 'science'. The paleontologist, they believed, is like a man who undertakes to study the principles of the internal combustion engine by standing on a street corner and watching the motor cars whiz by.
Tempo and Mode in Evolution (1944), 1.
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The central dogma, enunciated by Crick in 1958 and the keystone of molecular biology ever since, is likely to prove a considerable over-simplification. That is the heretical but inescapable conclusion stemming from experiments done in the past few months in two laboratories in the United States.
Anonymous
'News and Views', Nature, 1970, 226, 1198.
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The central problem of biological evolution is the nature of mutation, but hitherto the occurrence of this has been wholly refractory and impossible to influence by artificial means, although a control of it might obviously place the process of evolution in our hands.
'The Recent Findings in Heredity' (unpublished lecture, 1916, Lilly Library), 3. Quoted in Elof Axel Carlson, Genes, Radiation, and Society: The Life and Work of H. J. Muller (1981), 104.
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The century of biology upon which we are now well embarked is no matter of trivialities. It is a movement of really heroic dimensions, one of the great episodes in man’s intellectual history. The scientists who are carrying the movement forward talk in terms of nucleo-proteins, of ultracentrifuges, of biochemical genetics, of electrophoresis, of the electron microscope, of molecular morphology, of radioactive isotopes. But do not be misled by these horrendous terms, and above all do not be fooled into thinking this is mere gadgetry. This is the dependable way to seek a solution of the cancer and polio problems, the problems of rheumatism and of the heart. This is the knowledge on which we must base our solution of the population and food problems. This is the understanding of life.
Letter to H. M. H. Carsan (17 Jun 1949). Quoted in Raymond B. Fosdick, The Story of the Rockefeller Foundation (1952), 166.
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The chemical or physical inventor is always a Prometheus. There is no great invention, from fire to flying, which has not been hailed as an insult to some god. But if every physical and chemical invention is a blasphemy, every biological invention is a perversion. There is hardly one which, on first being brought to the notice of an observer from any nation which had not previously heard of their existence, would not appear to him as indecent and unnatural.
Lecture (4 Feb 1923) to the Heretics Society, Cambridge University, published in Daedalus; or, Science and the Future (1924), 44.
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The complexity of contemporary biology has led to an extreme specialization, which has inevitably been followed by a breakdown in communication between disciplines. Partly as a result of this, the members of each specialty tend to feel that their own work is fundamental and that the work of other groups, although sometimes technically ingenious, is trivial or at best only peripheral to an understanding of truly basic problems and issues. There is a familiar resolution to this problem but it is sometimes difficulty to accept emotionally. This is the idea that there are a number of levels of biological integration and that each level offers problems and insights that are unique to it; further, that each level finds its explanations of mechanism in the levels below, and its significances in the levels above it.
From 'Interaction of physiology and behavior under natural conditions', collected in R.I. Bowman (ed.), The Galapagos (1966), 39.
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The development of an organism … may be considered as the execution of a 'developmental program' present in the fertilized egg. … A central task of developmental biology is to discover the underlying algorithm from the course of development.
Aristid Lindenmayer and Grzegorz Rozenberg, Automata, Languages, Development (1976), v.
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The division between life and nonlife is perhaps an artificial one.
Speaking at an international meeting on the origins of life, quoted in E. Eckholm, 'Search for the Origins is Widening', International Herald Tribune (7 Jul 1986). As cited in Stuart R. Hameroff, Ultimate Computing: Biomolecular Consciousness and Nanotechnology (1987), 57.
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The essential character of a species in biology is, that it is a group of living organisms, separated from all other such groups by a set of distinctive characters, having relations to the environment not identical with those of any other group of organisms, and having the power of continuously reproducing its like. Genera are merely assemblages of a number of these species which have a closer resemblance to each other in certain important and often prominent characters than they have to any other species.
In 'The Method of Organic Evolution', Fortnightly Review (1895), 57, 441.
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The evidence indicates that woman is, on the whole, biologically superior to man.
In The Natural Superiority of Women (1952, 1999), 91.
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The existence of life must be considered as an elementary fact that can not be explained, but must be taken as a starting point in biology, in a similar way as the quantum of action, which appears as an irrational element from the point of view of classical mechanical physics, taken together with the existence of elementary particles, forms the foundation of atomic physics. The asserted impossibility of a physical or chemical explanation of the function peculiar to life would in this sense be analogous to the insufficiency of the mechanical analysis for the understanding of the stability of atoms.
'Light and Life', Nature, 1933, 131, 458.
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The experienced observer does more than merely report and recite. He guides the eager student to an understanding of the earth. He may chart the scientist’s steep, barren road of sober observation and strict deduction, or the artist’s gentle road of contemplation and empathy. And, finally, he may point out his own unique way, the path of the initiated, which leads him from the laboratories and libraries to the meadows and flower gardens of the living earth.
In 'Prologue', Conversation with the Earth (1954), 7. As translated by E.B. Garside from Gespräch mit der Erde (1947).
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The foundations of population genetics were laid chiefly by mathematical deduction from basic premises contained in the works of Mendel and Morgan and their followers. Haldane, Wright, and Fisher are the pioneers of population genetics whose main research equipment was paper and ink rather than microscopes, experimental fields, Drosophila bottles, or mouse cages. Theirs is theoretical biology at its best, and it has provided a guiding light for rigorous quantitative experimentation and observation.
'A Review of Some Fundamental Concepts and Problems of Population Genetics', Cold Spring Harbor Symposia on Quantitative Biology, 1955, 20, 13-14.
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The fundamental biological variant is DNA. That is why Mendel's definition of the gene as the unvarying bearer of hereditary traits, its chemical identification by Avery (confirmed by Hershey), and the elucidation by Watson and Crick of the structural basis of its replicative invariance, are without any doubt the most important discoveries ever made in biology. To this must be added the theory of natural selection, whose certainty and full significance were established only by those later theories.
In Jacques Monod and Austryn Wainhouse (trans.), Chance and Necessity: An Essay on the Natural Philosophy of Modern Biology (1971), 104.
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The history of the knowledge of the phenomena of life and of the organized world can be divided into two main periods. For a long time anatomy, and particularly the anatomy of the human body, was the α and ω of scientific knowledge. Further progress only became possible with the discovery of the microscope. A long time had yet to pass until through Schwann the cell was established as the final biological unit. It would mean bringing coals to Newcastle were I to describe here the immeasurable progress which biology in all its branches owes to the introduction of this concept of the cell concept. For this concept is the axis around which the whole of the modern science of life revolves.
Nobel Lecture (11 Dec 1908) 'Partial Cell Functions.' Collected in Nobel Lectures: Physiology or Medicine 1901-1921 (1967), 304.
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The hypothesis that man is not free is essential to the application of scientific method to the study of human behavior. The free inner man who is held responsible for the behavior of the external biological organism is only a prescientific substitute for the kinds of causes which are discovered in the course of a scientific analysis.
In Science and Human Behavior (1953), 447.
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The job of theorists, especially in biology, is to suggest new experiments. A good theory makes not only predictions, but surprising predictions that then turn out to be true. (If its predictions appear obvious to experimentalists, why would they need a theory?)
In What Mad Pursuit: A Personal View of Scientific Discovery (1988), 142.
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The living being is stable. It must be so in order not to be destroyed, dissolved, or disintegrated by the colossal forces, often adverse, which surround it. By apparent contradiction it maintains its stability only if it is excitable and capable of modifying itself according to external stimuli and adjusting its response to the stimulation. In a sense it is stable because it is modifiable—the slight instability is the necessary condition for the true stability of the organism.
In Dictionnaire de Physiologie (1900), Vol. 4, 72. English as quoted in Walter Bradford Cannon, The Wisdom of the Body (1932), 21, with French source citation footnoted on 26.
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The major credit I think Jim and I deserve … is for selecting the right problem and sticking to it. It’s true that by blundering about we stumbled on gold, but the fact remains that we were looking for gold. Both of us had decided, quite independently of each other, that the central problem in molecular biology was the chemical structure of the gene. … We could not see what the answer was, but we considered it so important that we were determined to think about it long and hard, from any relevant point of view.
In What Mad Pursuit (1990), 74-75.
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The material world is only the shell of the universe: the world of life are its inhabitants.
From The Spectator (25 Oct 1712), No. 519, collected in The Works of the Right Honorable Joseph Addison (1721), Vol. 4, 18.
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The most powerful antigen in human biology is a new idea.
Anonymous
Saying.
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The need to make music, and to listen to it, is universally expressed by human beings. I cannot imagine, even in our most primitive times, the emergence of talented painters to make cave paintings without there having been, near at hand, equally creative people making song. It is, like speech, a dominant aspect of human biology.
In 'The Music of This Sphere', The Lives of a Cell: Notes of a Biology Watcher (1974), 25.
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The next decade will perhaps raise us a step above despair to a cleaner, clearer wisdom and biology cannot fail to help in this. As we become increasingly aware of the ethical problems raised by science and technology, the frontiers between the biological and social sciences are clearly of critical importance—in population density and problems of hunger, psychological stress, pollution of the air and water and exhaustion of irreplaceable resources.
As quoted in 'H. Bentley Glass', New York Times (12 Jan 1970), 96.
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The only level of the hierarchy [of biological communities] that is both necessary and sufficient to meet all objectives is the ecosystem or some higher-level approach. The strategy selected should not only ensure the conservation of spotted owls, but all the intricate linkages that are associated with natural populations of spotted owls in naturally functioning ecosystems. Many of these are as yet unknown.
In The Fragmented Forest: Island Biogeography Theory and the Preservation of Biotic Diversity (1984), 107.
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The possibility that the infective agent may not contain nucleic acid and consist only of a peptide or peptide-polysaccharide complex which has replication properties within susceptible cells is intriguing. If peptides, short-chain proteins, or peptide/fatty-acid/ polysaccharide complexes activate nucleic-acid template activity in the host genes to produce identical infective particles, this would invalidate the accepted dogma of present-day molecular biology in which D.N.A. and R.N.A. templates control all biological activity.
'Scrapie: An Infective Peptide?', The Lancet (1972), i, 748.
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The problems of analyzing war operations are … rather nearer, in general, to many problems, say of biology or of economics, than to most problems of physics, where usually a great deal of numerical data are ascertainable about relatively simple phenomena.
In report at the British Association Annual Meeting, Dundee (30 Aug 1947), published in 'Operational Research in War and Peace', The Advancement of Science (1948), 17, 320-332. Collected in P.M.S. Blackett, Studies of War: Nuclear and Conventional (1962), 177.
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The progress of biology in the next century will lead to a recognition of the innate inequality of man. This is today most obviously visible in the United States.
In The Inequality of Man (1932), 18.
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The realization of the role played by DNA has had absolutely no consequence for either therapy or prevention…. Treatments for cancer remain today what they were before molecular biology was ever thought of: cut it out, burn it out, or poison it.
From review, 'Billions and Billions of Demons', of the book, The Demon-Haunted World: Science as a Candle in the Dark, by Carl Sagan, in New York Review of Books (9 Jan 1997).
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The results of mathematics are seldom directly applied; it is the definitions that are really useful. Once you learn the concept of a differential equation, you see differential equations all over, no matter what you do. This you cannot see unless you take a course in abstract differential equations. What applies is the cultural background you get from a course in differential equations, not the specific theorems. If you want to learn French, you have to live the life of France, not just memorize thousands of words. If you want to apply mathematics, you have to live the life of differential equations. When you live this life, you can then go back to molecular biology with a new set of eyes that will see things you could not otherwise see.
In 'A Mathematician's Gossip', Indiscrete Thoughts (2008), 213.
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The role of biology today, like the role of every other science, is simply to describe, and when it explains it does not mean that it arrives at finality; it only means that some descriptions are so charged with significance that they expose the relationship of cause and effect.
As quoted in Isaac Asimov and Jason A. Shulman (eds.), Isaac Asimov’s Book of Science and Nature Quotations (1988), 37. Webmaster so far has not found the primary source (can you help?)
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The student of biology is often struck with the feeling that historians, when dealing with the rise and fall of nations, do not generally view the phenomena from a sufficiently high biological standpoint. To me, at least, they seem to attach too much importance to individual rulers and soldiers, and to particular wars, policies, religions, and customs; while at the same time they make little attempt to extract the fundamental causes of national success or failure.
Introduction written by Ross for William Henry Samuel Jones, Malaria, a Neglected Factor in the History of Greece and Rome (1907), 1.
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The study of taxonomy in its broadest sense is probably the oldest branch of biology or natural history as well as the basis for all the other branches, since the first step in obtaining any knowledge of things about us is to discriminate between them and to learn to recognize them.
From paper presented to New York Entomological Society (12 Dec 1939), 'Some Aspects of Modern Taxonomy', published in Journal of the New York Entomological Society (Sep 1940), 48, No. 3, 245.
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The sun rises. In that short phrase, in a single fact, is enough information to keep biology, physics, and philosophy busy for all the rest of time.
In Lifetide: A Biology of the Unconscious (1979), 23.
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The techniques have galloped ahead of the concepts. We have moved away from studying the complexity of the organism; from processes and organisation to composition.
[Commenting that growing use of new technologies and techniques, from molecular biology to genomics, has proved a mixed blessing.]
Quoted in Andrew Jack, "An Acute Talent for Innovation", Financial Times (1 Feb 2009).
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The time has come to link ecology to economic and human development. When you have seen one ant, one bird, one tree, you have not seen them all. What is happening to the rain forests of Madagascar and Brazil will affect us all.
Quoted in Jamie Murphy and Andrea Dorfman, 'The Quiet Apocalypse,' Time (13 Oct 1986).
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The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
In 'The Nature of Vitalism', Of Molecules and Men (1966), 10.
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The universality of parasitism as an offshoot of the predatory habit negatives the position taken by man that it is a pathological phenomenon or a deviation from the normal processes of nature. The pathological manifestations are only incidents in a developing parasitism. As human beings intent on maintaining man's domination over nature we may regard parasitism as pathological insofar as it becomes a drain upon human resources. In our efforts to protect ourselves we may make every kind of sacrifice to limit, reduce, and even eliminate parasitism as a factor in human life. Science attempts to define the terms on which this policy of elimination may or may not succeed. We must first of all thoroughly understand the problem, put ourselves in possession of all the facts in order to estimate the cost. Too often it has been assumed that parasitism was abnormal and that it needed only a slight force to reestablish what was believed to be a normal equilibrium without parasitism. On the contrary, biology teaches us that parasitism is a normal phenomenon and if we accept this view we shall be more ready to pay the price of freedom as a permanent and ever recurring levy of nature for immunity from a condition to which all life is subject. The greatest victory of man over nature in the physical realm would undoubtedly be his own delivery from the heavy encumbrance of parasitism with which all life is burdened.
Parasitism and Disease (1934), 4.
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The whole biological community needs to be talking to one another so that people can get a comprehension of the turmoil in which our planet is involved at the moment, which is a biological turmoil above anything else.
In short extract from interview with Alice Roberts for the Biology: Changing the World project, 'Attenborough: The Earth is in “Biological Turmoil”', The Biologist (Apr/May 2015), 62, No. 2, 4.
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The work I have done has, already, been adequately rewarded and recognized. Imagination reaches out repeatedly trying to achieve some higher level of understanding, until suddenly I find myself momentarily alone before one new corner of nature’s pattern of beauty and true majesty revealed. That was my reward.
Nobel Banquet Speech (10 Dec 1965).
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There is a strange disparity between the sciences of inert matter and those of life. Astronomy, mechanics, and physics are based on concepts which can be expressed, tersely and elegantly, in mathematical language. They have built up a universe as harmonious as the monuments of ancient Greece. They weave about it a magnificent texture of calculations and hypotheses. They search for reality beyond the realm of common thought up to unutterable abstractions consisting only of equations of symbols. Such is not the position of biological sciences. Those who investigate the phenomena of life are as if lost in an inextricable jungle, in the midst of a magic forest, whose countless trees unceasingly change their place and their shape. They are crushed under a mass of facts, which they can describe but are incapable of defining in algebraic equations.
Man the Unknown (1935), 1.
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There is more to biology than rats, Drosophila, Caenorhabditis, and E. coli.
Concluding remarks in Foreword written by Mayr for Lynn Margulis and Dorion Sagan, Acquiring Genomes: A Theory of the Origins of Species (2003), xiv.
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There is no field of biological inquiry in which the influence of the Origin of Species is not traceable; the foremost men of science in every country are either avowed champions of its leading doctrines, or at any rate abstain from opposing them; a host of young and ardent investigators seek for and find inspiration and guidance in Mr. Darwin’s great work; and the general doctrine of Evolution, to one side of which it gives expression, finds in the phenomena of biology a firm base of operations whence it may conduct its conquest of the whole realm of nature.
From Lecture (19 Mar 1880) delivered at the Royal Institute 'The Coming of Age of The Origin of Species', printed in John Michels (ed.), Science (3 Jul 1880), 1, 15.
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There is not a “pure” science. By this I mean that physics impinges on astronomy, on the one hand, and chemistry and biology on the other. And not only does each support neighbors, but derives sustenance from them. The same can be said of chemistry. Biology is, perhaps, the example par excellence today of an “impure” science.
In 'Abstract' The Impurity of Science (19 Apr 1962), the printed version of the Robbins Lecture (27 Feb 1962) given at, Pomona College, Claremont, California, as published by Ernest O. Lawrence Radiation Laboratory, University of California.
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There is virtually nothing that has come from molecular biology that can be of any value to human living in the conventional sense of what is good, and quite tremendous possibilities of evil, again in the conventional sense.
In Changing Patterns (1968).
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This fundamental discovery that all bodies owe their origin to arrangements of single initial corpuscular type is the beacon that lights the history of the universe to our eyes. In its own way, matter obeyed from the beginning that great law of biology to which we shall have to recur time and time again, the law of “complexification.”
In Teilhard de Chardin and Bernard Wall (trans.), The Phenomenon of Man (1959, 2008), 48. Originally published in French as Le Phénomene Humain (1955).
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This irrelevance of molecular arrangements for macroscopic results has given rise to the tendency to confine physics and chemistry to the study of homogeneous systems as well as homogeneous classes. In statistical mechanics a great deal of labor is in fact spent on showing that homogeneous systems and homogeneous classes are closely related and to a considerable extent interchangeable concepts of theoretical analysis (Gibbs theory). Naturally, this is not an accident. The methods of physics and chemistry are ideally suited for dealing with homogeneous classes with their interchangeable components. But experience shows that the objects of biology are radically inhomogeneous both as systems (structurally) and as classes (generically). Therefore, the method of biology and, consequently, its results will differ widely from the method and results of physical science.
Atom and Organism: A New Approach to Theoretical Biology (1966), 34.
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This missing science of heredity, this unworked mine of knowledge on the borderland of biology and anthropology, which for all practical purposes is as unworked now as it was in the days of Plato, is, in simple truth, ten times more important to humanity than all the chemistry and physics, all the technical and indsutrial science that ever has been or ever will be discovered.
Mankind in the Making (1903), 72.
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Those who reject biological evolution do so, usually, not out of reason, but out of unjustified vanity.
Epigraph in Isaac Asimov’s Book of Science and Nature Quotations (1988), 86.
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Through the discovery of Buchner, Biology was relieved of another fragment of mysticism. The splitting up of sugar into CO2 and alcohol is no more the effect of a 'vital principle' than the splitting up of cane sugar by invertase. The history of this problem is instructive, as it warns us against considering problems as beyond our reach because they have not yet found their solution.
The Dynamics of Living Matter (1906), 22.
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Throughout the last four hundred years, during which the growth of science had gradually shown men how to acquire knowledge of the ways of nature and mastery over natural forces, the clergy have fought a losing battle against science, in astronomy and geology, in anatomy and physiology, in biology and psychology and sociology. Ousted from one position, they have taken up another. After being worsted in astronomy, they did their best to prevent the rise of geology; they fought against Darwin in biology, and at the present time they fight against scientific theories of psychology and education. At each stage, they try to make the public forget their earlier obscurantism, in order that their present obscurantism may not be recognized for what it is.
From An Outline of Intellectual Rubbish (1937, 1943), 6. Collected in The Basic Writings of Bertrand Russell (2009), 47.
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To be anthropocentric is to remain unaware of the limits of human nature, the significance of biological processes underlying human behavior, and the deeper meaning of long-term genetic evolution.
Tanner Lecture on Human Values, University of Michigan, 'Comparative Social Theory' (30 Mar 1979).
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To complete a PhD[,] I took courses in the history of philosophy. … As a result of my studies, I concluded that the traditional philosophy of science had little if anything to do with biology. … I had no use for a philosophy based on such an occult force as the vis vitalis. … But I was equally disappointed by the traditional philosophy of science, which was all based on logic, mathematics, and the physical sciences, and had adopted Descartes’ conclusion that an organism was nothing but a machine. This Cartesianism left me completely dissatisfied.
In 'Introduction', What Makes Biology Unique?: Considerations on the Autonomy of a Scientific Discipline (2007), 2.
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To complete a PhD[,] I took courses in the history of philosophy. … As a result of my studies, I concluded that the traditional philosophy of science had little if anything to do with biology. … I had no use for a philosophy based on such an occult force as the vis vitalis. … But I was equally disappointed by the traditional philosophy of science, which was all based on logic, mathematics, and the physical sciences, and had adopted Descartes’ conclusion that an organism was nothing but a machine. This Cartesianism left me completely dissatisfied.
In 'Introduction', What Makes Biology Unique?: Considerations on the Autonomy of a Scientific Discipline (2007), 2.
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To produce a really good biological theory one must try to see through the clutter produced by evolution to the basic mechanisms lying beneath them, realizing that they are likely to be overlaid by other, secondary mechanisms. What seems to physicists to be a hopelessly complicated process may have been what nature found simplest, because nature could only build on what was already there.
In What Mad Pursuit (1990), 139.
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To-day, science has withdrawn into realms that are hardly understanded of the people. Biology means very largely histology, the study of the cell by difficult and elaborate microscopical processes. Chemistry has passed from the mixing of simple substances with ascertained reactions, to an experimentation of these processes under varying conditions of temperature, pressure, and electrification—all requiring complicated apparatus and the most delicate measurement and manipulation. Similarly, physics has outgrown the old formulas of gravity, magnetism, and pressure; has discarded the molecule and atom for the ion, and may in its recent generalizations be followed only by an expert in the higher, not to say the transcendental mathematics.
Anonymous
‘Exit the Amateur Scientist.’ Editorial, The Nation, 23 August 1906, 83, 160.
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Until 1930 or thereabout biologists [using microscopes], in the situation of Astronomers and Astrophysicists, were permitted to see the objects of their interest, but not to touch them; the cell was as distant from us, as the stars and galaxies were from them.
Nobel Lecture, The Coming Age of the Cell, 12 Dec 1974
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We all came from the sea. And it is an interesting biological fact that all of us have, in our veins the exact same percentage of salt in our blood that exists in the ocean, and, therefore, we have salt in our blood, in our sweat, in our tears.
Speech at the America’s Cup Dinner (14 Sep 1962).
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We are at the dawn of a new era, the era of “molecular biology” as I like to call it, and there is an urgency about the need for more intensive application of physics and chemistry, and specially of structure analysis, that is still not sufficiently appreciated.
'On the Structure of Biological Fibres and the Problem of Muscle', Proceedings of the Royal Society of London, 1947, 134, 326.
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We are now witnessing, after the slow fermentation of fifty years, a concentration of technical power aimed at the essential determinants of heredity, development and disease. This concentration is made possible by the common function of nucleic acids as the molecular midwife of all reproductive particles. Indeed it is the nucleic acids which, in spite of their chemical obscurity, are giving to biology a unity which has so far been lacking, a chemical unity.
Nucleic Acid (1947), 266-7.
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We are profoundly ignorant about nature. Indeed, I regard this as the major discovery of the past hundred years of biology. It is, in its way, an illuminating piece of news.
Essay, 'The Hazards of Science', collected in The Medusa and the Snail: More Notes of a Biology Watcher (1979), 73.
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We know the laws of trial and error, of large numbers and probabilities. We know that these laws are part of the mathematical and mechanical fabric of the universe, and that they are also at play in biological processes. But, in the name of the experimental method and out of our poor knowledge, are we really entitled to claim that everything happens by chance, to the exclusion of all other possibilities?
From Nobel Prize Lecture (Dec 1974), 'The Coming Age of the Cell'. Collected in Jan Lindsten (ed.) Nobel Lectures, Physiology or Medicine 1971-1980 (1992).
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We must [it has been arued] go beyond reductionism to a holistic recognition that biology and culture interpenetrate in an inextricable manner.
An Urchin in the Storm (1988), 153.
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We must ascribe to all cells an independent vitality; that is, such combinations of molecules as occur in any single cell are capable of setting free the power by which it is enabled to take up fresh molecules.
In Theodor Schwann and Henry Smith (trans.), 'Theory of the Cells', Microscopical Researches Into the Accordance in the Structure and Growth of Animals and Plants (1839, 1847), 192.
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We must learn to think not only logically, but bio-logically.
In One Life at a Time, Please (1988), 68.
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We need science education to produce scientists, but we need it equally to create literacy in the public. Man has a fundamental urge to comprehend the world about him, and science gives today the only world picture which we can consider as valid. It gives an understanding of the inside of the atom and of the whole universe, or the peculiar properties of the chemical substances and of the manner in which genes duplicate in biology. An educated layman can, of course, not contribute to science, but can enjoy and participate in many scientific discoveries which as constantly made. Such participation was quite common in the 19th century, but has unhappily declined. Literacy in science will enrich a person’s life.
In Popular Mechanics (Sep 1961), 256
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We need to explore the possibility that homosexual bonding may be a biological mechanism.
In Pamela Weintraub (ed.), 'E. O. Wilson', The Omni Interviews (1984), 225.
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We no longer can talk of unearned “rights.” We’ll have to get back to working for “rights” to adequate food, housing, education, opportunity, a place in the sun—and not everybody is going to make the grade. I don’t see this obsession with the lowest strata of humanity, against all natural biologic experience. We must accept that life is unfair.
In Raymond Mungo, 'Dixy Lee Ray: How Madame Nuke Took Over Washington', Mother Jones (May 1977), 2, No. 4, 31.
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What can be more important than the science of life to any intelligent being who has the good fortune to be alive?
Epigraph in Isaac Asimov’s Book of Science and Nature Quotations (1988), 36.
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What is found in biology is mechanisms, mechanisms built with chemical components and that are often modified by other, later, mechanisms added to the earlier ones.
In What Mad Pursuit: A Personal View of Scientific Discovery (1988), 138.
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What politicians do not understand is that [Ian] Wilmut discovered not so much a technical trick as a new law of nature. We now know that an adult mammalian cell can fire up all the dormant genetic instructions that shut down as it divides and specializes and ages, and thus can become a source of new life. You can outlaw technique; you cannot repeal biology.
Writing after Wilmut's successful cloning of the sheep, Dolly, that research on the cloning of human beings cannot be suppressed.
'A Special Report on Cloning'. Charles Krauthammer in Time (10 Mar 1997).
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Whatever advantage can be attributed to logic in directing and strengthening the action of the understanding is found in a higher degree in mathematical study, with the immense added advantage of a determinate subject, distinctly circumscribed, admitting of the utmost precision, and free from the danger which is inherent in all abstract logic—of leading to useless and puerile rules, or to vain ontological speculations. The positive method, being everywhere identical, is as much at home in the art of reasoning as anywhere else: and this is why no science, whether biology or any other, can offer any kind of reasoning, of which mathematics does not supply a simpler and purer counterpart. Thus, we are enabled to eliminate the only remaining portion of the old philosophy which could even appear to offer any real utility; the logical part, the value of which is irrevocably absorbed by mathematical science.
In Auguste Comte and Harriet Martineau (trans.), Positive Philosophy (1858), Vol. 1, 326-327.
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Whatever the subject of any investigation may be, whether poetry, biology, ethics or torpedo warfare, the same scientific method of procedure must be followed. We must first unravel the complex and heterogeneous back to first principles, and then reason forward from the simple to the complex, from the homogeneous to the heterogeneous, from what we know to what we would learn. Such are the methods pursued by all successful inventors, scientific investigators and discoverers.
In The Science of Poetry and the Philosophy of Language (1910), ix.
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When I listen to a soprano sing a Handel aria with an astonishing coloratura from that particular larynx, I say to myself, there has to be a biological reason that was useful at some stage. The larynx of a human being did not evolve without having some function. And the only function I can see is sexual attraction.
From 'Interview: Of Mind and Matter: David Attenborough Meets Richard Dawkins', The Guardian (11 Sep 2010).
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When... the biologist is confronted with the fact that in the organism the parts are so adapted to each other as to give rise to a harmonious whole; and that the organisms are endowed with structures and instincts calculated to prolong their life and perpetuate their race, doubts as to the adequacy of a purely physiochemical viewpoint in biology may arise. The difficulties besetting the biologist in this problem have been rather increased than diminished by the discovery of Mendelian heredity, according to which each character is transmitted independently of any other character. Since the number of Mendelian characters in each organism is large, the possibility must be faced that the organism is merely a mosaic of independent hereditary characters. If this be the case the question arises: What moulds these independent characters into a harmonious whole? The vitalist settles this question by assuming the existence of a pre-established design for each organism and of a guiding 'force' or 'principle' which directs the working out of this design. Such assumptions remove the problem of accounting for the harmonious character of the organism from the field of physics or chemistry. The theory of natural selection invokes neither design nor purpose, but it is incomplete since it disregards the physiochemical constitution of living matter about which little was known until recently.
The Organism as a Whole: From a Physiochemical Viewpoint (1916), v-vi.
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While Occam’s razor is a useful tool in the physical sciences, it can be a very dangerous implement in biology. It is thus very rash to use simplicity and elegance as a guide in biological research.
In What Mad Pursuit: A Personal View of Scientific Discovery (1988), 138.
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Who—aside from certain big children who are indeed found in the natural sciences—still believes that the findings of astronomy, biology, physics, or chemistry could teach us anything about the meaning of the world?
Max Weber
From a Speech (1918) presented at Munich University, published in 1919, and collected in 'Wissenschaft als Beruf', Gessammelte Aufsätze zur Wissenschaftslehre (1922), 524-525. As given in H.H. Gerth and C. Wright-Mills (translators and eds.), 'Science as a Vocation', Max Weber: Essays in Sociology (1946), 142.
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Will it be possible to solve these problems? It is certain that nobody has thus far observed the transformation of dead into living matter, and for this reason we cannot form a definite plan for the solution of this problem of transformation. But we see that plants and animals during their growth continually transform dead into living matter, and that the chemical processes in living matter do not differ in principle from those in dead matter. There is, therefore, no reason to predict that abiogenesis is impossible, and I believe that it can only help science if the younger investigators realize that experimental abiogenesis is the goal of biology.
The Dynamics of Living Matter (1906), 223.
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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- 90 -
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- 40 -
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