… the United States was not built by those who waited and rested and wished to look behind them. This country was conquered by those who moved forward, and so will space.

...That day in the account of creation, or those days that are numbers according to its recurrence, are beyond the experience and knowledge of us mortal earthbound men. And if we are able to make any effort towards an understanding of those days, we ought not to rush forward with an ill considered opinion, as if no other reasonable and plausible interpretation could be offered.

…The present revolution of scientific thought follows in natural sequence on the great revolutions at earlier epochs in the history of science. Einstein’s special theory of relativity, which explains the indeterminateness of the frame of space and time, crowns the work of Copernicus who first led us to give up our insistence on a geocentric outlook on nature; Einstein's general theory of relativity, which reveals the curvature or non-Euclidean geometry of space and time, carries forward the rudimentary thought of those earlier astronomers who first contemplated the possibility that their existence lay on something which was not flat. These earlier revolutions are still a source of perplexity in childhood, which we soon outgrow; and a time will come when Einstein’s amazing revelations have likewise sunk into the commonplaces of educated thought.

…we are all inclined to ... direct our inquiry not by the matter itself, but by the views of our opponents; and, even when interrogating oneself, one pushes the inquiry only to the point at which one can no longer offer any opposition. Hence a good inquirer will be one who is ready in bringing forward the objections proper to the genus, and that he will be when he has gained an understanding of the differences.

“I’m not so sure he’s wrong about automobiles,” he said, “With all their speed forward they may be a step backward for civilization—that is, spiritual civilization … But automobiles have come, and they bring a greater change in our life than most of us expect. They are here, and almost all outward things are going to be different because of what they bring. They are going to alter war, and they are going to alter peace.”

[I]magine you want to know the sex of your unborn child. There are several approaches. You could, for example, do what the late film star ... Cary Grant did before he was an actor: In a carnival or fair or consulting room, you suspend a watch or a plumb bob above the abdomen of the expectant mother; if it swings left-right it's a boy, and if it swings forward-back it's a girl. The method works one time in two. Of course he was out of there before the baby was born, so he never heard from customers who complained he got it wrong. ... But if you really want to know, then you go to amniocentesis, or to sonograms; and there your chance of being right is 99 out of 100. ... If you really want to know, you go to science.

[Ignorance] of the principle of conservation of energy … does not prevent inventors without background from continually putting forward perpetual motion machines… Also, such persons undoubtedly have their exact counterparts in the fields of art, finance, education, and all other departments of human activity… persons who are unwilling to take the time and to make the effort required to find what the known facts are before they become the champions of unsupported opinions—people who take sides first and look up facts afterward when the tendency to distort the facts to conform to the opinions has become well-nigh irresistible.

[Technical courage means the] physician-scientist must be brave enough to adopt new methods. It is far too easy to learn one technique and then to repeat the same experiment over and over. In this fashion one can write many papers, receive large research grants, and remain solidly rooted in the middle of a scientific field. But the true innovator has the confidence to drop one set of experimental crutches and leap to another when he or she must move forward.

Theories thus become instruments, not answers to enigmas, in which we can rest. We don’t lie back upon them, we move forward, and, on occasion, make nature over again by their aid.

A natural law regulates the advance of science. Where only observation can be made, the growth of knowledge creeps; where laboratory experiments can be carried on, knowledge leaps forward.
[Attributed, probably incorrectly]

After having a wash I proceeded to the bar where—believe it or not—there was a white-coated barman who was not only serving drinks but also cigarettes! I hastened forward and rather timidly said ‘Can I have some cigarettes?’
‘What’s your rank?’ was the slightly unexpected reply.
‘I am afraid I haven’t got one,’ I answered.
‘Nonsense—everyone who comes here has a rank.’
‘I’m sorry but I just don’t have one.’
‘Now that puts me in a spot,’ said the barman, ‘for orders about cigarettes in this camp are clear—twenty for officers and ten for other ranks. Tell me what exactly are you?’
Now I really wanted those cigarettes so I drew myself up and said ‘I am the Professor of Chemistry at Manchester University.’
The barman contemplated me for about thirty seconds and then said ‘I’ll give you five.’
Since that day I have had few illusions about the importance of professors!

And having thus passed the principles of arithmetic, geometry, astronomy, and geography, with a general compact of physics, they may descend in mathematics to the instrumental science of trigonometry, and from thence to fortification, architecture, engineering, or navigation. And in natural philosophy they may proceed leisurely from the history of meteors, minerals, plants, and living creatures, as far as anatomy. Then also in course might be read to them out of some not tedious writer the institution of physic. … To set forward all these proceedings in nature and mathematics, what hinders but that they may procure, as oft as shall be needful, the helpful experiences of hunters, fowlers, fishermen, shepherds, gardeners, apothecaries; and in other sciences, architects, engineers, mariners, anatomists.

Around here, however, we don't look backwards for very long. We keep moving forward, opening up new doors, and doing new things, because we're curious and curiosity keeps leading us down new paths.

Arts and sciences in one and the same century have arrived at great perfection; and no wonder, since every age has a kind of universal genius, which inclines those that live in it to some particular studies; the work then, being pushed on by many hands, must go forward.

As much as we’ve enjoyed it up here, we’re also starting to look forward to seeing all the people back on Earth that we miss and love so much.

Astrophysicists closing in on the grand structure of matter and emptiness in the universe are ruling out the meatball theory, challenging the soap bubble theory, and putting forward what may be the strongest theory of all: that the cosmos is organized like a sponge.

Behold the mighty dinosaur,
Famous in prehistoric lore,
Not only for his power and strength
But for his intellectual length.
You will observe by these remains
The creature had two sets of brains—
One in his head (the usual place),
The other at his spinal base.
Thus he could reason 'A priori'
As well as 'A posteriori'.
No problem bothered him a bit
He made both head and tail of it.
So wise was he, so wise and solemn,
Each thought filled just a spinal column.
If one brain found the pressure strong
It passed a few ideas along.
If something slipped his forward mind
'Twas rescued by the one behind.
And if in error he was caught
He had a saving afterthought.
As he thought twice before he spoke
He had no judgment to revoke.
Thus he could think without congestion
Upon both sides of every question.
Oh, gaze upon this model beast
Defunct ten million years at least.

Being in love with the one parent and hating the other are among the essential constituents of the stock of psychical impulses which is formed at that time and which is of such importance in determining the symptoms of the later neurosis... This discovery is confirmed by a legend that has come down to us from classical antiquity: a legend whose profound and universal power to move can only be understood if the hypothesis I have put forward in regard to the psychology of children has an equally universal validity. What I have in mind is the legend of King Oedipus and Sophocles' drama which bears his name.

Dare to live the life you have dreamed for yourself. Go forward and make your dreams come true.

Every bird which flies has the thread of the infinite in its claw. Germination includes the hatching of a meteor and the tap of a swallow's bill breaking the egg, and it leads forward the birth of an earth-worm and the advent of Socrates.

Every body perseveres in its state of being at rest or of moving uniformly straight forward, except insofar as it is compelled to change its state by forces impressed.

Every great improvement has come after repeated failures. Virtually nothing comes out right the first time. Failures, repeated failures, are finger posts on the road to achievement. One fails forward toward success.

Every mathematical book that is worth reading must be read “backwards and forwards”, if I may use the expression. I would modify Lagrange’s advice a little and say, “Go on, but often return to strengthen your faith.” When you come on a hard or dreary passage, pass it over; and come back to it after you have seen its importance or found the need for it further on.

Forward, forward let us range,
Let the great world spin for ever down the ringing grooves of change.

Generally speaking, geologists seem to have been much more intent on making little worlds of their own, than in examining the crust of that which they inhabit. It would be much more desirable that facts should be placed in the foreground and theories in the distance, than that theories should be brought forward at the expense of facts. So that, in after times, when the speculations of the present day shall have passed away, from a greater accumulation of information, the facts may be readily seized and converted to account.

Here’s to the crazy ones. The misfits. The rebels. The troublemakers. The round heads in the square holes. The ones who see things differently. They’re not fond of rules. You can quote them. Disagree with them. Glorify or vilify them. But the only thing you can’t do is ignore them. Because they change things. They push the human race forward. And while some may see them as the crazy ones, we see genius. Because the people who are crazy enough to think they can change the world, are the ones who do.

I am absolutely convinced that no wealth in the world can help humanity forward, even in the hands of the most devoted worker. The example of great and pure individuals is the only thing that can lead us to noble thoughts and deeds. Money only appeals to selfishness and irresistibly invites abuse. Can anyone imagine Moses, Jesus or Gandhi armed with the moneybags of Carnegie?

I conceive that Lamarck was the first to bring it forward systematically & to 'go the whole orang' ... Yet evolutionists 'cannot be pooh-poohed & ought not to be so.'

I have been branded with folly and madness for attempting what the world calls impossibilities, and even from the great engineer, the late James Watt, who said ... that I deserved hanging for bringing into use the high-pressure engine. This has so far been my reward from the public; but should this be all, I shall be satisfied by the great secret pleasure and laudable pride that I feel in my own breast from having been the instrument of bringing forward new principles and new arrangements of boundless value to my country, and however much I may be straitened in pecuniary circumstances, the great honour of being a useful subject can never be taken from me, which far exceeds riches.

I have written many direct and indirect arguments for the Copernican view, but until now I have not dared to publish them, alarmed by the fate of Copernicus himself, our master. He has won for himself undying fame in the eyes of a few, but he has been mocked and hooted at by an infinite multitude (for so large is the number of fools). I would dare to come forward publicly with my ideas if there were more people of your [Johannes Kepler’s] way of thinking. As this is not the case, I shall refrain.

I never really paused for a moment to question the idea that the progressive Spiritualization of Matter—so clearly demonstrated to me by Paleontology—could be anything other, or anything less, than an irreversible process. By its gravitational nature, the Universe, I saw, was falling—falling forwards—in the direction of spirit as upon its stable form. In other words, Matter was not ultra-materialized as I would at first have believed, but was instead metamorphosed in Psyche.

I notice that, in the lecture … which Prof. Lowry gave recently, in Paris … he brought forward certain freak formulae for tartaric acid, in which hydrogen figures as bigamist … I may say, he but follows the loose example set by certain Uesanians, especially one G. N. Lewis, a Californian thermodynamiter, who has chosen to disregard the fundamental canons of chemistry—for no obvious reason other than that of indulging in premature speculation upon electrons as the cause of valency…

I propose to put forward an apology for mathematics; and I may be told that it needs none, since there are now few studies more generally recognized, for good reasons or bad, as profitable and praiseworthy.

I shall explain a System of the World differing in many particulars from any yet known, answering in all things to the common Rules of Mechanical Motions: This depends upon three Suppositions. First, That all Cœlestial Bodies whatsoever, have an attraction or gravitating power towards their own Centers, whereby they attract not only their own parts, and keep them from flying from them, as we may observe the Earth to do, but that they do also attract all the other Cœlestial bodies that are within the sphere of their activity; and consequently that not only the Sun and Moon have an influence upon the body and motion the Earth, and the Earth upon them, but that Mercury also Venus, Mars, Saturn and Jupiter by their attractive powers, have a considerable influence upon its motion in the same manner the corresponding attractive power of the Earth hath a considerable influence upon every one of their motions also. The second supposition is this, That all bodies whatsoever that are put into a direct and simple motion, will continue to move forward in a streight line, till they are by some other effectual powers deflected and bent into a Motion, describing a Circle, Ellipse, or some other more compounded Curve Line. The third supposition is, That these attractive powers are so much the more powerful in operating, by how much the nearer the body wrought upon is to their own Centers. Now what these several degrees are I have not yet experimentally verified; but it is a notion, which if fully prosecuted as it ought to be, will mightily assist the Astronomer to reduce all the Cœlestial Motions to a certain rule, which I doubt will never be done true without it. He that understands the nature of the Circular Pendulum and Circular Motion, will easily understand the whole ground of this Principle, and will know where to find direction in Nature for the true stating thereof. This I only hint at present to such as have ability and opportunity of prosecuting this Inquiry, and are not wanting of Industry for observing and calculating, wishing heartily such may be found, having myself many other things in hand which I would first compleat and therefore cannot so well attend it. But this I durst promise the Undertaker, that he will find all the Great Motions of the World to be influenced by this Principle, and that the true understanding thereof will be the true perfection of Astronomy.

If it is true as Whewell says, that the essence of the triumphs of Science and its progress consists in that it enables us to consider evident and necessary, views which our ancestors held to be unintelligible and were unable to comprehend, then the extension of the number concept to include the irrational, and we will at once add, the imaginary, is the greatest forward step which pure mathematics has ever taken.

If it were possible for a metaphysician to be a golfer, he might perhaps occasionally notice that his ball, instead of moving forward in a vertical plane (like the generality of projectiles, such as brickbats and cricket balls), skewed away gradually to the right. If he did notice it, his methods would naturally lead him to content himself with his caddies’s remark-“ye heeled that yin,” or “Ye jist sliced it.” … But a scientific man is not to be put off with such flimsy verbiage as that. He must know more. What is “Heeling”, what is “slicing”, and why would either operation (if it could be thoroughly carried out) send a ball as if to cover point, thence to long slip, and finally behind back-stop? These, as Falstaff said, are “questions to be asked.”

If the study of all these sciences which we have enumerated, should ever bring us to their mutual association and relationship, and teach us the nature of the ties which bind them together, I believe that the diligent treatment of them will forward the objects which we have in view, and that the labor, which otherwise would be fruitless, will be well bestowed.

If we ascribe the ejection of the proton to a Compton recoil from a quantum of 52 x 10⁶ electron volts, then the nitrogen recoil atom arising by a similar process should have an energy not greater than about 400,000 volts, should produce not more than about 10,000 ions, and have a range in the air at N.T.P. of about 1-3mm. Actually, some of the recoil atoms in nitrogen produce at least 30,000 ions. In collaboration with Dr. Feather, I have observed the recoil atoms in an expansion chamber, and their range, estimated visually, was sometimes as much as 3mm. at N.T.P.
These results, and others I have obtained in the course of the work, are very difficult to explain on the assumption that the radiation from beryllium is a quantum radiation, if energy and momentum are to be conserved in the collisions. The difficulties disappear, however, if it be assumed that the radiation consists of particles of mass 1 and charge 0, or neutrons. The capture of the a-particle by the Be⁹ nucleus may be supposed to result in the formation of a C¹² nucleus and the emission of the neutron. From the energy relations of this process the velocity of the neutron emitted in the forward direction may well be about 3 x 10⁹ cm. per sec. The collisions of this neutron with the atoms through which it passes give rise to the recoil atoms, and the observed energies of the recoil atoms are in fair agreement with this view. Moreover, I have observed that the protons ejected from hydrogen by the radiation emitted in the opposite direction to that of the exciting a-particle appear to have a much smaller range than those ejected by the forward radiation.
This again receives a simple explanation on the neutron hypothesis.

If, again with the light of science, we trace forward into the future the condition of our globe, we are compelled to admit that it cannot always remain in its present condition; that in time, the store of potential energy which now exists in the sun and in the bodies of celestial space which may fall into it will be dissipated in radiant heat, and consequently the earth, from being the theatre of life, intelligence, of moral emotions, must become a barren waste.

Impressed force is the action exerted on a body to change its state either of resting or of moving uniformly straight forward.

In a University we are especially bound to recognise not only the unity of science itself, but the communion of the workers in science. We are too apt to suppose that we are congregated here merely to be within reach of certain appliances of study, such as museums and laboratories, libraries and lecturers, so that each of us may study what he prefers. I suppose that when the bees crowd round the flowers it is for the sake of the honey that they do so, never thinking that it is the dust which they are carrying from flower to flower which is to render possible a more splendid array of flowers, and a busier crowd of bees, in the years to come. We cannot, therefore, do better than improve the shining hour in helping forward the cross-fertilization of the sciences.

Inherent force of matter is the power of resisting by which every body, so far as it is able, perseveres in its state either of resting or of moving uniformly straight forward.

It is also a good rule not to put overmuch confidence in the observational results that are put forward until they are confirmed by theory.

It is no good to try to stop knowledge from going forward. Ignorance is never better that knowledge.
Note: Although attributed as his viewpoint to Enrico Fermi, it is probably not a direct quote by him.

It was a dark and stormy night, so R. H. Bing volunteered to drive some stranded mathematicians from the fogged-in Madison airport to Chicago. Freezing rain pelted the windscreen and iced the roadway as Bing drove on—concentrating deeply on the mathematical theorem he was explaining. Soon the windshield was fogged from the energetic explanation. The passengers too had beaded brows, but their sweat arose from fear. As the mathematical description got brighter, the visibility got dimmer. Finally, the conferees felt a trace of hope for their survival when Bing reached forward—apparently to wipe off the moisture from the windshield. Their hope turned to horror when, instead, Bing drew a figure with his finger on the foggy pane and continued his proof—embellishing the illustration with arrows and helpful labels as needed for the demonstration.

It will be contributing to bring forward the moment in which, seeing clearer into the nature of things, and having learnt to distinguish real knowledge from what has only the appearance of it, we shall be led to seek for exactness in every thing.

Many people are shrinking from the future and from participation in the movement toward a new, expanded reality. And, like homesick travelers abroad, they are focusing their anxieties on home. The reasons are not far to seek. We are at a turning point in human history. … We could turn our attention to the problems that going to the moon certainly will not solve … But I think this would be fatal to our future. … A society that no longer moves forward does not merely stagnate; it begins to die.

Mediocre men often have the most acquired knowledge. It is in the darker. It is in the darker regions of science that great men are recognized; they are marked by ideas which light up phenomena hitherto obscure and carry science forward.

Most people like to believe something is or is not true. Great scientists tolerate ambiguity very well. They believe the theory enough to go ahead; they doubt it enough to notice the errors and faults so they can step forward and create the new replacement theory. If you believe too much you’ll never notice the flaws; if you doubt too much you won’t get started. It requires a lovely balance.

My kingdom is as wide as the world, and my desire has no limit. I go forward always, freeing spirits and weighing worlds, without fear, without compassion, without love, and without God. Men call me science.

My two Jamaican cousins … were studying engineering. “That’s where the money is,” Mom advised. … I was to be an engineering major, despite my allergy to science and math. … Those who preceded me at CCNY include the polio vaccine discoverer, Dr. Jonas Salk … and eight Nobel Prize winners. … In class, I stumbled through math, fumbled through physics, and did reasonably well in, and even enjoyed, geology. All I ever looked forward to was ROTC.

Neither the Army nor the Navy is of any protection, or very slight protection, against aerial raids. We may therefore look forward with certainty to the time that is coming, and indeed is almost now at hand, when sea power and land power will be secondary to air power, and that nation which gains control of the air will practically control the world.

Nevertheless, scientific method is not the same as the scientific spirit. The scientific spirit does not rest content with applying that which is already known, but is a restless spirit, ever pressing forward towards the regions of the unknown, and endeavouring to lay under contribution for the special purpose in hand the knowledge acquired in all portions of the wide field of exact science. Lastly, it acts as a check, as well as a stimulus, sifting the value of the evidence, and rejecting that which is worthless, and restraining too eager flights of the imagination and too hasty conclusions.

One and all
We lend an ear—nay, Science takes thereto—
Encourages the meanest who has racked
Nature until he gains from her some fact,
To state what truth is from his point of view,
Mere pin-point though it be: since many such
Conduce to make a whole, she bids our friend
Come forward unabashed and haply lend
His little life-experience to our much
Of modern knowledge.

Our country is now at war and the only way out is forward. I would not change one word I have spoken against war but that is no longer the issue. We must now stand together.

Our educational system is like an automobile which has strong rear lights, brightly illuminating the past. But looking forward things are barely discernible.

People will not look forward to posterity, who never look backward to their ancestors.

Psychogenesis has led to man. Now it effaces itself, relieved or absorbed by another and a higher function—the engendering and subsequent development of the mind, in one word noogenesis. When for the first time in a living creature instinct perceived itself in its own mirror, the whole world took a pace forward.

Science and technology, like all original creations of the human spirit, are unpredictable. If we had a reliable way to label our toys good and bad, it would be easy to regulate technology wisely. But we can rarely see far enough ahead to know which road leads to damnation. Whoever concerns himself with big technology, either to push it forward or to stop it, is gambling in human lives.

Science has increased our lifespan considerably. Now we can look forward to paying our taxes at least ten years longer.

Science is a capital or fund perpetually reinvested; it accumulates, rolls up, is carried forward by every new man. Every man of science has all the science before him to go upon, to set himself up in business with. What an enormous sum Darwin availed himself of and reinvested! Not so in literature; to every poet, to every artist, it is still the first day of creation, so far as the essentials of his task are concerned. Literature is not so much a fund to be reinvested as it is a crop to be ever new-grown.

Science is dangerous. There is no question but that poison gas, genetic engineering, and nuclear weapons and power stations are terrifying. It may be that civilization is falling apart and the world we know is coming to an end. In that case, why no turn to religion and look forward to the Day of Judgment, ... [being] lifted into eternal bliss ... [and] watching the scoffers and disbelievers writhe forever in torment.

Science seldom proceeds in the straightforward logical manner imagined by outsiders. Instead, its steps forward (and sometimes backward) are often very human events in which personalities and cultural traditions play major roles.

Since men are really interested in nothing but their own opinions, every one who puts forward an opinion looks about him right and left for means of strengthening himself and others in it.

Some men said the atomic bomb should never have been built; researchers should have stopped working when they had realized that the bomb was feasible. Enrico did not think this would have been a sensible solution. It is no good trying to stop knowledge from going forward. Whatever Nature has in store for mankind, unpleasant as it may be, men must accept, for ignorance is never better than knowledge.
Note: Although attributed as his viewpoint to Enrico Fermi, it is probably not a direct quote by him.

Such is the tendency of the human mind to speculation, that on the least idea of an analogy between a few phenomena, it leaps forward, as it were, to a cause or law, to the temporary neglect of all the rest; so that, in fact, almost all our principal inductions must be regarded as a series of ascents and descents, and of conclusions from a few cases, verified by trial on many.

The 'stream' we call science always flows forward; sometimes reactionary beavers block its flow, but the stream is never defeated by this; it accumulates, gathers strength; its waters get over the barrage and continue on their course. The advancement of science is the advancement of God, for science is nothing but human intelligence, and human intelligence is the most valuable treasure God has bequeathed us.

The alchemists of past centuries tried hard to make the elixir of life: ... Those efforts were in vain; it is not in our power to obtain the experiences and the views of the future by prolonging our lives forward in this direction. However, it is well possible in a certain sense to prolong our lives backwards by acquiring the experiences of those who existed before us and by learning to know their views as well as if we were their contemporaries. The means for doing this is also an elixir of life.

The century of biology upon which we are now well embarked is no matter of trivialities. It is a movement of really heroic dimensions, one of the great episodes in man’s intellectual history. The scientists who are carrying the movement forward talk in terms of nucleo-proteins, of ultracentrifuges, of biochemical genetics, of electrophoresis, of the electron microscope, of molecular morphology, of radioactive isotopes. But do not be misled by these horrendous terms, and above all do not be fooled into thinking this is mere gadgetry. This is the dependable way to seek a solution of the cancer and polio problems, the problems of rheumatism and of the heart. This is the knowledge on which we must base our solution of the population and food problems. This is the understanding of life.

The crocodile cannot turn its head. Like science, it must always go forward with all-devouring jaws.

The difficulties connected with my criterion of demarcation (D) are important, but must not be exaggerated. It is vague, since it is a methodological rule, and since the demarcation between science and nonscience is vague. But it is more than sharp enough to make a distinction between many physical theories on the one hand, and metaphysical theories, such as psychoanalysis, or Marxism (in its present form), on the other. This is, of course, one of my main theses; and nobody who has not understood it can be said to have understood my theory.
The situation with Marxism is, incidentally, very different from that with psychoanalysis. Marxism was once a scientific theory: it predicted that capitalism would lead to increasing misery and, through a more or less mild revolution, to socialism; it predicted that this would happen first in the technically highest developed countries; and it predicted that the technical evolution of the 'means of production' would lead to social, political, and ideological developments, rather than the other way round.
But the (so-called) socialist revolution came first in one of the technically backward countries. And instead of the means of production producing a new ideology, it was Lenin's and Stalin's ideology that Russia must push forward with its industrialization ('Socialism is dictatorship of the proletariat plus electrification') which promoted the new development of the means of production.
Thus one might say that Marxism was once a science, but one which was refuted by some of the facts which happened to clash with its predictions (I have here mentioned just a few of these facts).
However, Marxism is no longer a science; for it broke the methodological rule that we must accept falsification, and it immunized itself against the most blatant refutations of its predictions. Ever since then, it can be described only as nonscience—as a metaphysical dream, if you like, married to a cruel reality.
Psychoanalysis is a very different case. It is an interesting psychological metaphysics (and no doubt there is some truth in it, as there is so often in metaphysical ideas), but it never was a science. There may be lots of people who are Freudian or Adlerian cases: Freud himself was clearly a Freudian case, and Adler an Adlerian case. But what prevents their theories from being scientific in the sense here described is, very simply, that they do not exclude any physically possible human behaviour. Whatever anybody may do is, in principle, explicable in Freudian or Adlerian terms. (Adler's break with Freud was more Adlerian than Freudian, but Freud never looked on it as a refutation of his theory.)
The point is very clear. Neither Freud nor Adler excludes any particular person's acting in any particular way, whatever the outward circumstances. Whether a man sacrificed his life to rescue a drowning, child (a case of sublimation) or whether he murdered the child by drowning him (a case of repression) could not possibly be predicted or excluded by Freud's theory; the theory was compatible with everything that could happen—even without any special immunization treatment.
Thus while Marxism became non-scientific by its adoption of an immunizing strategy, psychoanalysis was immune to start with, and remained so. In contrast, most physical theories are pretty free of immunizing tactics and highly falsifiable to start with. As a rule, they exclude an infinity of conceivable possibilities.

The edge of the sea is a strange and beautiful place. All through the long history of Earth it has been an area of unrest where waves have broken heavily against the land, where the tides have pressed forward over the continents, receded, and then returned. For no two successive days is the shore line precisely the same. Not only do the tides advance and retreat in their eternal rhythms, but the level of the sea itself is never at rest. It rises or falls as the glaciers melt or grow, as the floor of the deep ocean basins shifts under its increasing load of sediments, or as the Earth’s crust along the continental margins warps up or down in adjustment to strain and tension. Today a little more land may belong to the sea, tomorrow a little less. Always the edge of the sea remains an elusive and indefinable boundary.

The fact that Science walks forward on two feet, namely theory and experiment, is nowhere better illustrated than in the two fields for slight contributions to which you have done me the great honour of awarding the the Nobel Prize in Physics for the year 1923. Sometimes it is one foot that is put forward first, sometimes the other, but continuous progress is only made by the use of both—by theorizing and then testing, or by finding new relations in the process of experimenting and then bringing the theoretical foot up and pushing it on beyond, and so on in unending alterations.

The glory of medicine is that it is constantly moving forward, that there is always more to learn. The ills of today do not cloud the horizon of tomorrow, but act as a spur to greater effort.

The longer you can look back, the farther you can look forward.

The origin of an adaptive structure and the purposes it comes to fulfill are only chance combinations. Purposefulness is a very human conception for usefulness. It is usefulness looked at backwards. Hard as it is to imagine, inconceivably hard it may appear to many, that there is no direct relation between the origin of useful variations and the ends they come to serve, yet the modern zoologist takes his stand as a man of science on this ground. He may admit in secret to his father confessor, the metaphysician, that his poor intellect staggers under such a supposition, but he bravely carries forward his work of investigation along the only lines that he has found fruitful.

The personal views of the lecturer may seem to be brought forward with undue exclusiveness, but, as it is his business to give a clear exposition of the actual state of the science which he treats, he is obliged to define with precision the principles, the correctness of which he has proved by his own experience.

The Principle of Uncertainty is a bad name. In science or outside of it we are not uncertain; our knowledge is merely confined, within a certain tolerance. We should call it the Principle of Tolerance. And I propose that name in two senses: First, in the engineering sense, science has progressed, step by step, the most successful enterprise in the ascent of man, because it has understood that the exchange of information between man and nature, and man and man, can only take place with a certain tolerance. But second, I also use the word, passionately, about the real world. All knowledge, all information between human beings, can only be exchanged within a play of tolerance. And that is true whether the exchange is in science, or in literature, or in religion, or in politics, or in any form of thought that aspires to dogma. It’s a major tragedy of my lifetime and yours that scientists were refining, to the most exquisite precision, the Principle of Tolerance, and turning their backs on the fact that all around them, tolerance was crashing to the ground beyond repair. The Principle of Uncertainty or, in my phrase, the Principle of Tolerance, fixed once for all the realization that all knowledge is limited. It is an irony of history that at the very time when this was being worked out there should rise, under Hitler in Germany and other tyrants elsewhere, a counter-conception: a principle of monstrous certainty. When the future looks back on the 1930s it will think of them as a crucial confrontation of culture as I have been expounding it, the ascent of man, against the throwback to the despots’ belief that they have absolute certainty. It is said that science will dehumanize people and turn them into numbers. That is false: tragically false. Look for yourself. This is the concentration camp and crematorium at Auschwitz. This is where people were turned into numbers. Into this pond were flushed the ashes of four million people. And that was not done by gas. It was done by arrogance. It was done by dogma. It was done by ignorance. When people believe that they have absolute knowledge, with no test in reality this is how they behave. This is what men do when they aspire to the knowledge of gods. Science is a very human form of knowledge. We are always at the brink of the known; we always feel forward for what is to be hoped. Every judgment in science stands on the edge of error, and is personal. Science is a tribute to what we can know although we are fallible. In the end, the words were said by Oliver Cromwell: “I beseech you, in the bowels of Christ: Think it possible you may be mistaken.” We have to cure ourselves of the itch for absolute knowledge and power. We have to close the distance between the push-button order and the human act. We have to touch people. [Referring to Heisenberg’s Uncertainty Principle.]

The role of hypothesis in research can be discussed more effectively if we consider first some examples of discoveries which originated from hypotheses. One of the best illustrations of such a discovery is provided by the story of Christopher Columbus’ voyage; it has many of the features of a classic discovery in science. (a) He was obsessed with an idea—that since the world is round he could reach the Orient by sailing West, (b) the idea was by no means original, but evidently he had obtained some additional evidence from a sailor blown off his course who claimed to have reached land in the west and returned, (c) he met great difficulties in getting someone to provide the money to enable him to test his idea as well as in the actual carrying out of the experimental voyage, (d) when finally he succeeded he did not find the expected new route, but instead found a whole new world, (e) despite all evidence to the contrary he clung to the bitter end to his hypothesis and believed that he had found the route to the Orient, (f) he got little credit or reward during his lifetime and neither he nor others realised the full implications of his discovery, (g) since his time evidence has been brought forward showing that he was by no means the first European to reach America.

The stakes are immense, the task colossal, the time is short. But we may hope–we must hope–that man’s own creation, man’s own genius, will not destroy him. Scholars, indeed all men, must move forward in the faith of that philosopher who held that there is no problem the human reason can propound which the human reason cannot reason out.

The teaching of elementary mathematics should be conducted so that the way should be prepared for the building upon them of the higher mathematics. The teacher should always bear in mind and look forward to what is to come after. The pupil should not be taught what may be sufficient for the time, but will lead to difficulties in the future. … I think the fault in teaching arithmetic is that of not attending to general principles and teaching instead of particular rules. … I am inclined to attack Teaching of Mathematics on the grounds that it does not dwell sufficiently on a few general axiomatic principles.

The theory of the lung as a gland has justified its existence and done excellent service in bringing forward facts, which shall survive any theoretical construction that has been or may hereafter be put upon them.

There is no more convincing proof of the truth of a comprehensive theory than its power of absorbing and finding a place for new facts, and its capability of interpreting phenomena which had been previously looked upon as unaccountable anomalies. It is thus that the law of universal gravitation and the undulatory theory of light have become established and universally accepted by men of science. Fact after fact has been brought forward as being apparently inconsistent with them, and one alter another these very facts have been shown to be the consequences of the laws they were at first supposed to disprove. A false theory will never stand this test. Advancing knowledge brings to light whole groups of facts which it cannot deal with, and its advocates steadily decrease in numbers, notwithstanding the ability and scientific skill with which it may have been supported.

There is scarce any one invention, which this nation has produced in our age, but it has some way or other been set forward by his assistance. ... He is indeed a man born for the good of mankind, and for the honour of his country. ... So I may thank God, that Dr. Wilkins was an Englishman, for wherever he had lived, there had been the chief seat of generous knowledge and true philosophy.

There is, however, no universal recipe for scientific advance. It is a matter of groping forward into terra incognita of the outer world by means of methods which should be adapted to the circumstances.

These were moments of exhilaration and ecstasy! A glimpse of this wonder can be the reward of a lifetime. Could it be that excitement and ennobling feelings like these have kept us scientists marching forward forever?

Thought and science follow their own law of development; they are slowly elaborated in the growth and forward pressure of humanity, in what Shakespeare calls
...The prophetic soul,
Of the wide world dreaming on things to come.

Through radio I look forward to a United States of the World. Radio is standardizing the peoples of the Earth, English will become the universal language because it is predominantly the language of the ether. The most important aspect of radio is its sociological influence. (1926)

Time was when all the parts of the subject were dissevered, when algebra, geometry, and arithmetic either lived apart or kept up cold relations of acquaintance confined to occasional calls upon one another; but that is now at an end; they are drawn together and are constantly becoming more and more intimately related and connected by a thousand fresh ties, and we may confidently look forward to a time when they shall form but one body with one soul.

To look backward for a while is to refresh the eye, to restore it, and to render it more fit for its prime function of looking forward.

To seek in the great accumulation of the already-said the text that resembles "in advance" a later text, to ransack history in order to rediscover the play of anticipations or echoes, to go right back to the first seeds or to go forward to the last traces, to reveal in a work its fidelity to tradition or its irreducible uniqueness, to raise or lower its stock of originality, to say that the Port -Royal grammarians invented nothing, or to discover that Cuvier had more predecessors than one thought, these are harmless enough amusements for historians who refuse to grow up.

We are in the presence of a recruiting drive systematically and deliberately undertaken by American business, by American universities, and to a lesser extent, American government, often initiated by talent scouts specially sent over here to buy British brains and preempt them for service of the U.S.A. … I look forward earnestly to the day when some reform of the American system of school education enables them to produce their own scientists so that, in an amiable free trade of talent, there may be adequate interchange between our country and theirs, and not a one-way traffic.

We can continue to try and clean up the gutters all over the world and spend all of our resources looking at just the dirty spots and trying to make them clean. Or we can lift our eyes up and look into the skies and move forward in an evolutionary way.

We claim to be more moral than other nations, and to conquer and govern and tax and plunder weaker peoples for their good! While robbing them we actually claim to be benefactors! And then we wonder, or profess to wonder, why other Governments hate us! Are they not fully justified in hating us? Is it surprising that they seek every means to annoy us, that they struggle to get navies to compete with us, and look forward to a time when some two or three of them may combine together and thoroughly humble and cripple us? And who can deny that any just Being, looking at all the nations of the earth with impartiality and thorough knowledge, would decide that we deserve to be humbled, and that it might do us good?

We find it a law of our state of being that where only observation can be made the growth of knowledge creeps; where experiment can be made knowledge leaps forward.

We wish to put forward a radically different structure for the salt of deoxyribose nucleic acid. This structure has two helical chains each coiled round the same axis (see diagram).
[Co-author with Francis Crick]

What is called science today consists of a haphazard heap of information, united by nothing, often utterly unnecessary, and not only failing to present one unquestionable truth, but as often as not containing the grossest errors, today put forward as truths, and tomorrow overthrown.

When all beliefs are challenged together, the just and necessary ones have a chance to step forward and to re-establish themselves alone.

When external objects are impressed on the sensory nerves, they excite vibrations in the aether residing in the pores of these nerves... Thus it seems that light affects both the optic nerve and the aether and ... the affections of the aether are communicated to the optic nerve, and vice versa. And the same may be observed of frictions of the skin, taste, smells and sounds... Vibrations in the aether will agitate the small particles of the medullary substance of the sensory nerves with synchronous vibrations... up to the brain... These vibrations are motions backwards and forwards of small particles, of the same kind with the oscillations of pendulums, and the tremblings of the particles of the sounding bodies (but) exceedingly short and small, so as not to have the least efficacy to disturb or move the whole bodies of the nerves... That the nerves themselves should vibrate like musical strings is highly absurd.

When I observe the luminous progress and expansion of natural science in modern times, I seem to myself like a traveller going eastwards at dawn, and gazing at the growing light with joy, but also with impatience; looking forward with longing to the advent of the full and final light, but, nevertheless, having to turn away his eyes when the sun appeared, unable to bear the splendour he had awaited with so much desire.

When one considers in its length and in its breadth the importance of this question of the education of the nation's young, the broken lives, the defeated hopes, the national failures, which result from the frivolous inertia with which it is treated, it is difficult to restrain within oneself a savage rage. In the conditions of modern life the rule is absolute, the race which does not value trained intelligence is doomed. Not all your heroism, not all your social charm, not all your wit, not all your victories on land or at sea, can move back the finger of fate. To-day we maintain ourselves. To-morrow science will have moved forward yet one more step, and there will be no appeal from the judgment which will then be pronounced on the uneducated.

When the state is shaken to its foundations by internal or external events, when commerce, industry and all trades shall be at a stand, and perhaps on the brink of ruin; when the property and fortune of all are shaken or changed, and the inhabitants of towns look forward with dread and apprehension to the future, then the agriculturalist holds in his hand the key to the money chest of the rich, and the savings-box of the poor; for political events have not the slightest influence on the natural law, which forces man to take into his system, daily, a certain number of ounces of carbon and nitrogen.
Reflecting on events of 1848.

When you make a mistake, don’t look back at it long. Take the reason of the thing into your mind, and then look forward. Mistakes are lessons of wisdom. The past cannot be changed. The future is yet in your power.

When young Galileo, then a student at Pisa, noticed one day during divine service a chandelier swinging backwards and forwards, and convinced himself, by counting his pulse, that the duration of the oscillations was independent of the arc through which it moved, who could know that this discovery would eventually put it in our power, by means of the pendulum, to attain an accuracy in the measurement of time till then deemed impossible, and would enable the storm-tossed seaman in the most distant oceans to determine in what degree of longitude he was sailing?