“Any specialty, if important, is too important to be left to the specialists.” After all, the specialist cannot function unless he concentrates more or less entirely on his specialty and, in doing so, he will ignore the vast universe lying outside and miss important elements that ought to help guide his judgment. He therefore needs the help of the nonspecialist, who, while relying on the specialist for key information, can yet supply the necessary judgment based on everything else… Science, therefore, has become too important to be left to the scientists.

[Louis Rendu, Bishop of Annecy] collects observations, makes experiments, and tries to obtain numerical results; always taking care, however, so to state his premises and qualify his conclusions that nobody shall be led to ascribe to his numbers a greater accuracy than they merit. It is impossible to read his work, and not feel that he was a man of essentially truthful mind and that science missed an ornament when he was appropriated by the Church.

Across the road from my cabin was a huge clear-cut—hundreds of acres of massive spruce stumps interspersed with tiny Douglas firs—products of what they call “Reforestation,” which I guess makes the spindly firs en masse a “Reforest,” which makes an individual spindly fir a “Refir,” which means you could say that Weyerhauser, who owns the joint, has Refir Madness, since they think that sawing down 200-foot-tall spruces and replacing them with puling 2-foot Refirs is no different from farming beans or corn or alfalfa. They even call the towering spires they wipe from the Earth’s face forever a “crop”--as if they’d planted the virgin forest! But I'm just a fisherman and may be missing some deeper significance in their nomenclature and stranger treatment of primordial trees.

And don’t forget one in the command module.... And thanks for putting me on relay, Houston. I was missing all the action.

As a scientist Miss [Rosalind] Franklin was distinguished by extreme clarity and perfection in everything she undertook. Her photographs are among the most beautiful X-ray photographs of any substance ever taken.

As much as we’ve enjoyed it up here, we’re also starting to look forward to seeing all the people back on Earth that we miss and love so much.

Bad times have a scientific value. These are occasions a good learner would not miss.

Change is the law of life. And those who look only to the past or the present are certain to miss the future.

Even fairly good students, when they have obtained the solution of the problem and written down neatly the argument, shut their books and look for something else. Doing so, they miss an important and instructive phase of the work. ... A good teacher should understand and impress on his students the view that no problem whatever is completely exhausted.

For the environmentalists, The Space Option is the ultimate environmental solution. For the Cornucopians, it is the technological fix that they are relying on. For the hard core space community, the obvious by-product would be the eventual exploration and settlement of the solar system. For most of humanity however, the ultimate benefit is having a realistic hope in a future with possibilities.... If our species does not soon embrace this unique opportunity with sufficient commitment, it may miss its one and only chance to do so. Humanity could soon be overwhelmed by one or more of the many challenges it now faces. The window of opportunity is closing as fast as the population is increasing. Our future will be either a Space Age or a Stone Age.

Four college students taking a class together, had done so well through the semester, and each had an “A”. They were so confident, the weekend before finals, they went out partying with friends. Consequently, on Monday, they overslept and missed the final. They explained to the professor that they had gone to a remote mountain cabin for the weekend to study, but, unfortunately, they had a flat tire on the way back, didn’t have a spare, and couldn’t get help for a long time. As a result, they missed the final. The professor kindly agreed they could make up the final the following day. When they arrived the next morning, he placed them each in separate rooms, handed each one a test booklet, and told them to begin. The the first problem was simple, worth 5 points. Turning the page they found the next question, written: “(For 95 points): Which tire?”

I do not think we can impose limits on research. Through hundreds of thousands of years, man’s intellectual curiosity has been essential to all the gains we have made. Although in recent times we have progressed from chance and hit-or-miss methods to consciously directed research, we still cannot know in advance what the results may be. It would be regressive and dangerous to trammel the free search for new forms of truth.

I don’t believe in God, but I miss him.

I feel a desperation to make people see what we are doing to the environment, what a mess we are making of our world. At this point, the more people I reach, the more I accomplish. … I miss Gombe and my wonderful years in the forest But if I were to go back to that, I wouldn’t feel I was doing what I should be doing.

I was depressed at that time. I was in analysis. I was suicidal as a matter of fact and would have killed myself, but I was in analysis with a strict Freudian, and, if you kill yourself, they make you pay for the sessions you miss.

I wouldn’t miss this opportunity for anything. For the chance to work on these conservation issues, to serve my country, to work for this president, I’d do it all over again, every single minute.

I’ve learned that regardless of your relationship with your parents, you’ll miss them when they’re gone from your life.

If God didn't create life this way, He certainly missed a good bet.

In an age of specialization people are proud to be able to do one thing well, but if that is all they know about, they are missing out on much else life has to offer.

Inventions that are not made, like babies that are not born, are rarely missed. In the absence of new developments, old ones may seem very impressive for quite a long while.

It required unusual inquisitiveness to pursue the development of scientific curiosities such as charged pith balls, the voltaic cell, and the electrostatic machine. Without such endeavors and the evolution of associated instrumentation, initially of purely scientific interest, most of the investigations that lead to the basic equations of electromagnetism would have been missed. … We would have been deprived of electromagnetic machinery as well as knowledge of electromagnetic waves.

Life’s greatest tragedy is to lose God and not to miss him.

Miss Stevens’s work is characterized by its precision, and by a caution that seldom ventures far from the immediate observation. Her contributions are models of brevity—a brevity amounting at times almost to meagerness.

Modern cytological work involves an intricacy of detail, the significance of which can be appreciated by the specialist alone; but Miss Stevens had a share in a discovery of importance, and her work will be remembered for this, when the minutiae of detailed investigations that she carried out have become incorporated in the general body of the subject.

My first view - a panorama of brilliant deep blue ocean, shot with shades of green and gray and white - was of atolls and clouds. Close to the window I could see that this Pacific scene in motion was rimmed by the great curved limb of the Earth. It had a thin halo of blue held close, and beyond, black space. I held my breath, but something was missing - I felt strangely unfulfilled. Here was a tremendous visual spectacle, but viewed in silence. There was no grand musical accompaniment; no triumphant, inspired sonata or symphony. Each one of us must write the music of this sphere for ourselves.

Nor do I know any study which can compete with mathematics in general in furnishing matter for severe and continued thought. Metaphysical problems may be even more difficult; but then they are far less definite, and, as they rarely lead to any precise conclusion, we miss the power of checking our own operations, and of discovering whether we are thinking and reasoning or merely fancying and dreaming.

On coming down the stairs at dinner Tris [Trismegistus = Frankland] who walked before me seemed impressed by a mechanical impulse which impelled him along the corridor with a fervid velocity. On reaching the stair bottom I discovered the cause of the attraction. Miss Edmondson, like a pure planet, had checked his gravitating tendencies and lo! He stood radiant with smiles dropping joysparkes from his eyes as he clasped her hand. His countenance became a transparency through which the full proportions of his soul shone manifest; his blood tingled from his eyebrows to his finger ends, and wealthy with rich emotions his face became the avenue of what he felt.

On my tests, I [had] … what I called a “two and fifty question.” Two points if they got it right; 50 points off if they missed it.
Now this isn’t as unfair as it seems because much of life is that way. You can do right all your life and nobody says anything. But you go out and make one little mistake and everybody censures you.

Only to often on meeting scientific men, even those of genuine distiction, one finds that they are dull fellows and very stupid. They know one thing to excess; they know nothing else. Pursuing facts too doggedly and unimaginatively, they miss all the charming things that are not facts. ... Too much learning, like too little learning, is an unpleasant and dangerous thing.

Opportunity is missed by most people because it is dressed in overalls and looks like work.

Our ability to live and work on other places in the solar system will end up giving us the science and technology that we need to save the species. I’m talking about human beings. I’d hate to miss all that fun.

Shoot for the moon. Even if you miss, you’ll land among the stars

Take the sum of human achievement in action, in science, in art, in literature—subtract the work of the men above forty, and while we should miss great treasures, even priceless treasures, we would practically be where we are today. … The effective, moving, vitalizing work of the world is done between the ages of twenty-five and forty.

Th’invention all admir’d, and each, how he
To be th’inventor miss’d; so easy it seem’d,
Once found, which yet unfound most would have thought
Impossible.

That he [Einstein] may sometimes have missed the target in his speculations, as, for example, in his hypothesis of light quanta, cannot really be held much against him.

The Columbia is lost; there are no survivors. … In an age when space flight has come to seem almost routine, it is easy to overlook the dangers of travel by rocket, and the difficulties of navigating the fierce outer atmosphere of the Earth. These astronauts knew the dangers, and they faced them willingly, knowing they had a high and noble purpose in life. Because of their courage and daring idealism, we will miss them all the more. … The cause in which they died will continue. Mankind is led into the darkness beyond our world by the inspiration of discovery and the longing to understand. Our journey into space will go on.

The discovery of an interaction among the four hemes made it obvious that they must be touching, but in science what is obvious is not necessarily true. When the structure of hemoglobin was finally solved, the hemes were found to lie in isolated pockets on the surface of the subunits. Without contact between them how could one of them sense whether the others had combined with oxygen? And how could as heterogeneous a collection of chemical agents as protons, chloride ions, carbon dioxide, and diphosphoglycerate influence the oxygen equilibrium curve in a similar way? It did not seem plausible that any of them could bind directly to the hemes or that all of them could bind at any other common site, although there again it turned out we were wrong. To add to the mystery, none of these agents affected the oxygen equilibrium of myoglobin or of isolated subunits of hemoglobin. We now know that all the cooperative effects disappear if the hemoglobin molecule is merely split in half, but this vital clue was missed. Like Agatha Christie, Nature kept it to the last to make the story more exciting. There are two ways out of an impasse in science: to experiment or to think. By temperament, perhaps, I experimented, whereas Jacques Monod thought.

The engineer who counts cost as nothing as compared to the result, who holds himself above the consideration of dollars and cents, has missed his vocation.

The general root of superstition [is that] men observe when things hit, and not when they miss, and commit to memory the one, and pass over the other.

The greatest of all spectral classifiers, Antonia Maury had two strikes on her: the biggest one was, she was a woman. A woman had no chance at anything in astronomy except at Harvard in the 1880’s and 1890’s. And even there, things were rough. It now turns out that her director, E.C. Pickering, did not like the way she classified; she then refused to change to suit him; and after her great publication in Harvard Annals 28 (1897), she left Harvard—and in a sense, astronomy. ... I would say the most remarkable phenomenological investigation in modern astronomy is Miss Maury’s work in Harvard Annals 28. She didn’t have anything astrophysical to go on. Investigations between 1890 and 1900 were the origin of astrophysics. But these were solar, mostly. And there Miss Maury was on the periphery. I’ve seen pictures of groups, where she’d be standing away a little bit to one side of the other people, a little bit in the background. It was a very sad thing. When Hertzsprung wrote Pickering to congratulate him on Miss Maury’s work that had led to Hertzsprung’s discovery of super giants, Pickering is supposed to have replied that Miss Maury’s work was wrong — could not possibly be correct.

The Humorless Person: I have a friend who has about as much sense of humor as the wooden Indian of commerce. Some time ago he made a trip through the Mammoth Cave of Kentucky. … He did his sight-seeing very thoroughly. He didn’t miss a single ramification in that great crack in the face of Mother Nature. … I asked him what he thought of the Mammoth Cave. “Well,” said he, “taking it as a hole, it is all right.”

The invention all admired, and each how he
To be the inventor missed; so easy it seemed,
Once found, which yet unfounded most would have thought,
Impossible!

The line separating investment and speculation, which is never bright and clear, becomes blurred still further when most market participants have recently enjoyed triumphs. Nothing sedates rationality like large doses of effortless money. After a heady experience of that kind, normally sensible people drift into behavior akin to that of Cinderella at the ball. They know that overstaying the festivities—that is, continuing to speculate in companies that have gigantic valuations relative to the cash they are likely to generate in the future—will eventually bring on pumpkins and mice. But they nevertheless hate to miss a single minute of what is one helluva party. Therefore, the giddy participants all plan to leave just seconds before midnight. There’s a problem, though: They are dancing in a room in which the clocks have no hands.

The nineteenth century is a turning point in history, simply on account of the work of two men, Darwin and Renan, the one the critic of the Book of Nature, the other the critic of the books of God. Not to recognise this is to miss the meaning of one of the most important eras in the progress of the world.

The teacher can seldom afford to miss the questions: What is the unknown? What are the data? What is the condition? The student should consider the principal parts of the problem attentively, repeatedly, and from various sides.

There's many a true word spoken in jest; scientists are abominably solemn; therefore scientists miss many a true word.

To me education is a leading out of what is already there in the pupil’s soul. To Miss Mackay it is a putting in of something that is not there, and that is not what I call education, I call it intrusion.

Truth is a remarkable thing. We cannot miss knowing some of it. But we cannot know it entirely.

We are like the inhabitants of an isolated valley in New Guinea who communicate with societies in neighboring valleys (quite different societies, I might add) by runner and by drum. When asked how a very advanced society will communicate, they might guess by an extremely rapid runner or by an improbably large drum. They might not guess a technology beyond their ken. And yet, all the while, a vast international cable and radio traffic passes over them, around them, and through them... We will listen for the interstellar drums, but we will miss the interstellar cables. We are likely to receive our first messages from the drummers of the neighboring galactic valleys - from civilizations only somewhat in our future. The civilizations vastly more advanced than we, will be, for a long time, remote both in distance and in accessibility. At a future time of vigorous interstellar radio traffic, the very advanced civilizations may be, for us, still insubstantial legends.

We often think, naïvely, that missing data are the primary impediments to intellectual progress–just find the right facts and all problems will dissipate. But barriers are often deeper and more abstract in thought. We must have access to the right metaphor, not only to the requisite information. Revolutionary thinkers are not, primarily, gatherers of fact s, but weavers of new intellectual structures.

When I saw the alpha-helix and saw what a beautiful, elegant structure it was, I was thunderstruck and was furious with myself for not having built this, but on the other hand, I wondered, was it really right?
So I cycled home for lunch and was so preoccupied with the turmoil in my mind that didn’t respond to anything. Then I had an idea, so I cycled back to the lab. I realized that I had a horse hair in a drawer. I set it up on the X-ray camera and gave it a two hour exposure, then took the film to the dark room with my heart in my mouth, wondering what it showed, and when I developed it, there was the 1.5 angstrom reflection which I had predicted and which excluded all structures other than the alpha-helix.
So on Monday morning I stormed into my professor’s office, into Bragg’s office and showed him this, and Bragg said, 'Whatever made you think of that?' And I said, 'Because I was so furious with myself for having missed that beautiful structure.' To which Bragg replied coldly, 'I wish I had made you angry earlier.'