[Man] … his origin, his growth, his hopes and fears, his loves and his beliefs are but the outcome of accidental collocations of atoms; that no fire, no heroism, no intensity of thought and feeling can preserve an individual life beyond the grave; that all the labour of the ages, all the devotion, all the inspiration, all the noonday brightness of human genius are destined to extinction in the vast death of the solar system, and that the whole temple of Man's achievement must inevitably be buried beneath the debris of a universe in ruins…

[My dream dinner guest is] Charles Darwin. It’s an obvious answer, but it’s the truth. Think of any problem and before you start theorising, just check up whether Charles Darwin mentioned it in one of those green books sitting on your shelf. Whether it’s earthworms, human gestures or the origin of species, the observations that man made are unbelievable. He touched on so many subjects. Then, Alexander von Humboldt, the last polymath. There was no aspect of the natural world that he wasn’t curious about or didn’t write about in Kosmos, an extraordinary book.

[The science of cosmology is] closest to the soul because it has to do with origins, and that somehow generates strong opinions.

[To] explain the phenomena of the mineral kingdom ... systems are usually reduced to two classes, according as they refer to the origin of terrestrial bodies to FIRE or to WATER; and ... their followers have of late been distinguished by the fanciful names of Vulcanists and Neptunists. To the former of these Dr HUTTON belongs much more than to the latter; though, as he employs the agency both of fire and water in his system, he cannot, in strict propriety, be arranged with either.

Considerate la vostra semenza:
Fatti non foste a viver come bruti,
Ma per seguir virtute e conoscenza.
Consider your origins: you were not made to live as brutes, but to follow virtue and knowledge.

Dilbert: It took weeks but I’ve calculated a new theory about the origin of the universe. According to my calculations it didn’t start with a “Big Bang” at all—it was more of “Phhbwt” sound. You may be wondering about the practical applications of the “Little Phhbwt” theory.
Dogbert: I was wondering when you’ll go away.

Ich have auf eine geringe Vermutung eine gefährliche Reise gewagt und erblicke schon die Vorgebirge neuer Länder. Diejenigen, welche die Herzhaftigheit haben die Untersuchung fortzusetzen, werden sie betreten.
Upon a slight conjecture [on the origin of the solar system] I have ventured on a dangerous journey and I already behold the foothills of new lands. Those who have the courage to continue the search will set foot on them.

Ogni nostra cognitione prīcipia da sentimēti.
All our knowledge has its origin in our preceptions.

Where faith commences, science ends. Both these arts of the human mind must be strictly kept apart from each other. Faith has its origin in the poetic imagination; knowledge, on the other hand, originates in the reasoning intelligence of man. Science has to pluck the blessed fruits from the tree of knowledge, unconcerned whether these conquests trench upon the poetical imaginings of faith or not.

A bewildering assortment of (mostly microscopic) life-forms has been found thriving in what were once thought to be uninhabitable regions of our planet. These hardy creatures have turned up in deep, hot underground rocks, around scalding volcanic vents at the bottom of the ocean, in the desiccated, super-cold Dry Valleys of Antarctica, in places of high acid, alkaline, and salt content, and below many meters of polar ice. ... Some deep-dwelling, heat-loving microbes, genetic studies suggest, are among the oldest species known, hinting that not only can life thrive indefinitely in what appear to us totally alien environments, it may actually originate in such places.

A hundred years ago the study of life was often pursued, and also presented to the public, in a highly unified way. Darwin, as everyone knows, in addressing the world at large began his story with the history of pigeons and ended it with the breeding of primroses, having made excursions on the way into the origins of coral reefs and of the races of Man.

A sound Physics of the Earth should include all the primary considerations of the earth's atmosphere, of the characteristics and continual changes of the earth's external crust, and finally of the origin and development of living organisms. These considerations naturally divide the physics of the earth into three essential parts, the first being a theory of the atmosphere, or Meteorology, the second, a theory of the earth's external crust, or Hydrogeology, and the third, a theory of living organisms, or Biology.

A thing is either alive or it isn’t; there is nothing that is almost alive. There is but the remotest possibility of the origin of life by spontaneous generation, and every likelihood that Arrhenius is right when he dares to claim that life is a cosmic phenomenon, something that drifts between the spheres, like light, and like light transiently descends upon those fit to receive it.

About weak points [of the Origin] I agree. The eye to this day gives me a cold shudder, but when I think of the fine known gradations, my reason tells me I ought to conquer the cold shudder.

According to my derivative hypothesis, a change takes place first in the structure of the animal, and this, when sufficiently advanced, may lead to modifications of habits… . “Derivation” holds that every species changes, in time, by virtue of inherent tendencies thereto. “Natural Selection” holds that no such change can take place without the influence of altered external circumstances educing or selecting such change… . The hypothesis of “natural selection” totters on the extension of a conjectural condition, explanatory of extinction to the majority of organisms, and not known or observed to apply to the origin of any species.

According to the conclusion of Dr. Hutton, and of many other geologists, our continents are of definite antiquity, they have been peopled we know not how, and mankind are wholly unacquainted with their origin. According to my conclusions drawn from the same source, that of facts, our continents are of such small antiquity, that the memory of the revolution which gave them birth must still be preserved among men; and thus we are led to seek in the book of Genesis the record of the history of the human race from its origin. Can any object of importance superior to this be found throughout the circle of natural science?

All admit that the mountains of the globe are situated mostly along the border regions of the continents (taking these regions as 300 to 1000 miles or more in width), and that over these same areas the sedimentary deposits have, as a general thing, their greatest thickness. At first thought, it would seem almost incredible that the upliftings of mountains, whatever their mode of origin, should have taken place just where the earth’s crust, through these sedimentary accumulations, was the thickest, and where, therefore, there was the greatest weight to be lifted. … Earthquakes show that even now, in this last of the geological ages, the same border regions of the continents, although daily thickening from the sediments borne to the ocean by rivers, are the areas of the greatest and most frequent movements of the earth’s crust. (1866)
[Thus, the facts were known long ago; the explanation by tectonic activity came many decades later.]

All material Things seem to have been composed of the hard and solid Particles … variously associated with the first Creation by the Counsel of an intelligent Agent. For it became him who created them to set them in order: and if he did so, it is unphilosophical to seek for any other Origin of the World, or to pretend that it might arise out of a Chaos by the mere Laws of Nature.

All palaetiological sciences, all speculations which attempt to ascend from the present to the remote past, by the chain of causation, do also, by an inevitable consequence, urge us to look for the beginning of the state of things which we thus contemplate; but in none of these cases have men been able, by the aid of science, to arrive at a beginning which is homogeneous with the known course of events. The first origin of language, of civilization, of law and government, cannot be clearly made out by reasoning and research; and just as little, we may expect, will a knowledge of the origin of the existing and extinct species of plants and animals, be the result of physiological and geological investigation.

All sciences originated among the sons of Israel, the reason being the existence of prophecy among them which made their perfection in the sciences amazing.

Already at the origin of the species man was equal to what he was destined to become.

Although it be a known thing subscribed by all, that the foetus assumes its origin and birth from the male and female, and consequently that the egge is produced by the cock and henne, and the chicken out of the egge, yet neither the schools of physicians nor Aristotle’s discerning brain have disclosed the manner how the cock and its seed doth mint and coin the chicken out of the egge.

An example of such emergent phenomena is the origin of life from non-living chemical compounds in the oldest, lifeless oceans of the earth. Here, aided by the radiation energy received from the sun, countless chemical materials were synthesized and accumulated in such a way that they constituted, as it were, a primeval “soup.” In this primeval soup, by infinite variations of lifeless growth and decay of substances during some billions of years, the way of life was ultimately reached, with its metabolism characterized by selective assimilation and dissimilation as end stations of a sluiced and canalized flow of free chemical energy.

An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going. But this should not be taken to imply that there are good reasons to believe that it could not have started on the earth by a perfectly reasonable sequence of fairly ordinary chemical reactions. The plain fact is that the time available was too long, the many microenvironments on the earth’s surface too diverse, the various chemical possibilities too numerous and our own knowledge and imagination too feeble to allow us to be able to unravel exactly how it might or might not have happened such a long time ago, especially as we have no experimental evidence from that era to check our ideas against.

At the origin, the [space travel] pioneers of the greatest adventure of all times were motivated by the drive to explore, by the pure spirit of conquest, by the lofty desire to open up new fields to human genius. … From their exceptional journeys, they all came back with the revelation of beauty. Beauty of the black sky, beauty and variety of our planet, beauty of the Earth seen from the Moon, girdled by a scintillating belt of equatorial thunderstorms. They all emphasize that our planet is one, that borderlines are artificial, that humankind is one single community on board spaceship Earth. They all insist that this fragile gem is at our mercy and that we must all endeavor to protect it.

At times the [radio telescope] records exhibited a feature characteristic of interference, occurring some time later than the passage of the two known sources. This intermittent feature was curious, and I recall saying once that we would have to investigate the origin of that interference some day. We joked that it was probably due to the faulty ignition of some farm hand returning from a date.

But in my opinion we can now be assured sufficiently that no animals, however small they may be, take their origin in putrefaction, but exclusively in procreation… For seeing that animals, from the largest down to the little despised animal, the flea, have animalcules in their semen, seeing also that some of the vessels of the lungs of horses and cows consist of rings and that these rings can occur on the flea's veins, why cannot we come to the conclusion that as well as the male sperm of that large animal the horse and similar animals, and of all manner of little animals, the flea included, is furnished with animalcules (and other intestines, for I have often been astonished when I beheld the numerous vessels in a flea), why, I say should not the male sperm of the smallest animals, smaller than a flea may even the very smallest animalcules have the perfection that we find in a flea.

But the idea that any of the lower animals have been concerned in any way with the origin of man—is not this degrading? Degrading is a term, expressive of a notion of the human mind, and the human mind is liable to prejudices which prevent its notions from being invariably correct. Were we acquainted for the first time with the circumstances attending the production of an individual of our race, we might equally think them degrading, and be eager to deny them, and exclude them from the admitted truths of nature.

Coming to the question of life being found on other planets, Professor Haldane apologized for discoursing, as a mere biologist, on a subject on which we had been expecting a lecture by a physicist [J. D. Bernal]. He mentioned three hypotheses:
(a) That life had a supernatural origin,
(b) That it originated from inorganic materials, and (c) That life is a constituent of the Universe and can only arise from pre-existing life. The first hypothesis, he said, should be taken seriously, and he would proceed to do so. From the fact that there are 400,000 species of beetle on this planet, but only 8,000 species of mammals, he concluded that the Creator, if he exists, has a special preference for beetles, and so we might be more likely to meet them than any other type of animal on a planet which would support life.

Concepts that have proven useful in ordering thi ngs easily achieve such authority over us that we forget their earthly origins and accept them as unalterable givens.

Controlled research … endeavors to pick out of the web of nature’s activities some single strand and trace it towards its origin and its terminus and determine its relation to other strands.

Darwin abolished special creations, contributed the Origin of Species and hitched all life together in one unbroken procession of Siamese Twins, the whole evolved by natural and orderly processes from one microscopic parent germ.

Darwin deals with evolution, not with origin.

Darwin's Origin of Species had come into the theological world like a plough into an ant-hill. Everywhere those thus rudely awakened from their old comfort and repose had swarmed forth angry and confused. Reviews, sermons, books light and heavy, came flying at the new thinker from all sides.

During my stay in London I resided for a considerable time in Clapham Road in the neighbourhood of Clapham Common... One fine summer evening I was returning by the last bus 'outside' as usual, through the deserted streets of the city, which are at other times so full of life. I fell into a reverie (Träumerei), and 10, the atoms were gambolling before my eyes! Whenever, hitherto, these diminutive beings had appeared to me, they had always been in motion: but up to that time I had never been able to discern the nature of their motion. Now, however, I saw how, frequently, two smaller atoms united to form a pair: how the larger one embraced the two smaller ones: how still larger ones kept hold of three or even four of the smaller: whilst the whole kept whirling in a giddy dance. I saw how the larger ones formed a chain, dragging the smaller ones after them but only at the ends of the chain. I saw what our past master, Kopp, my highly honoured teacher and friend has depicted with such charm in his Molekular-Welt: but I saw it long before him. The cry of the conductor 'Clapham Road', awakened me from my dreaming: but I spent part of the night in putting on paper at least sketches of these dream forms. This was the origin of the 'Structural Theory'.

Each species may have had its origin in a single pair, or individual, where an individual was sufficient, and species may have been created in succession at such times and in such places as to enable them to multiply and endure for an appointed period, and occupy an appointed space on the globe.

Education, then, beyond all other devices of human origin, is the great equalizer of the conditions of men–the balance-wheel of the social machinery.

Every philosophical thinker hails it [The Origin of Species] as a veritable Whitworth gun in the armoury of liberalism.

Except the blind forces of Nature, nothing moves in this world which is not Greek in its origin.

Fifty years from now if an understanding of man’s origins, his evolution, his history, his progress is not in the common place of the school books we shall not exist.

For a long time it has been known that the first systems of representations with which men have pictured to themselves the world and themselves were of religious origin. There is no religion that is not a cosmology at the same time that it is a speculation upon divine things. If philosophy and the sciences were born of religion, it is because religion began by taking the place of the sciences and philosophy.

For I am yearning to visit the limits of the all-nurturing Earth, and Oceans, from whom the gods are sprung.

For it is too bad that there are so few who seek the truth and so few who do not follow a mistaken method in philosophy. This is not, however, the place to lament the misery of our century, but to rejoice with you over such beautiful ideas for proving the truth. So I add only, and I promise, that I shall read your book at leisure; for I am certain that I shall find the noblest things in it. And this I shall do the more gladly, because I accepted the view of Copernicus many years ago, and from this standpoint I have discovered from their origins many natural phenomena, which doubtless cannot be explained on the basis of the more commonly accepted hypothesis.

For it is too bad that there are so few who seek the truth and so few who do not follow a mistaken method in philosophy. This is not, however, the place to lament the misery of our century, but to rejoice with you over such beautiful ideas for proving the truth. So I add only, and I promise, that I shall read your book at leisure; for I am certain that I shall find the noblest things in it. And this I shall do the more gladly, because I accepted the view of Copernicus many years ago, and from this standpoint I have discovered from their origins many natural phenomena, which doubtless cannot be explained on the basis of the more commonly accepted hypothesis.

For the evolution of science by societies the main requisite is the perfect freedom of communication between each member and anyone of the others who may act as a reagent.
The gaseous condition is exemplified in the soiree, where the members rush about confusedly, and the only communication is during a collision, which in some instances may be prolonged by button-holing.
The opposite condition, the crystalline, is shown in the lecture, where the members sit in rows, while science flows in an uninterrupted stream from a source which we take as the origin. This is radiation of science. Conduction takes place along the series of members seated round a dinner table, and fixed there for several hours, with flowers in the middle to prevent any cross currents.
The condition most favourable to life is an intermediate plastic or colloidal condition, where the order of business is (1) Greetings and confused talk; (2) A short communication from one who has something to say and to show; (3) Remarks on the communication addressed to the Chair, introducing matters irrelevant to the communication but interesting to the members; (4) This lets each member see who is interested in his special hobby, and who is likely to help him; and leads to (5) Confused conversation and examination of objects on the table.
I have not indicated how this programme is to be combined with eating.

For the little that one has reflected on the origin of our knowledge, it is easy to perceive that we can acquire it only by means of comparison. That which is absolutely incomparable is wholly incomprehensible. God is the only example that we could give here. He cannot be comprehended, because he cannot be compared. But all which is susceptible of comparison, everything that we can perceive by different aspects, all that we can consider relatively, can always be judged according to our knowledge.

Formerly one sought the feeling of the grandeur of man by pointing to his divine origin: this has now become a forbidden way, for at its portal stands the ape, together with other gruesome beasts, grinning knowingly as if to say: no further in this direction! One therefore now tries the opposite direction: the way mankind is going shall serve as proof of his grandeur and kinship with God. Alas this, too, is vain! At the end of this way stands the funeral urn of the last man and gravedigger (with the inscription “nihil humani a me alienum puto”). However high mankind may have evolved—and perhaps at the end it will stand even lower than at the beginning!— it cannot pass over into a higher order, as little as the ant and the earwig can at the end of its “earthly course” rise up to kinship with God and eternal life. The becoming drags the has-been along behind it: why should an exception to this eternal spectacle be made on behalf of some little star or for any little species upon it! Away with such sentimentalities!

Fractal is a word invented by Mandelbrot to bring together under one heading a large class of objects that have [played] … an historical role … in the development of pure mathematics. A great revolution of ideas separates the classical mathematics of the 19th century from the modern mathematics of the 20th. Classical mathematics had its roots in the regular geometric structures of Euclid and the continuously evolving dynamics of Newton. Modern mathematics began with Cantor’s set theory and Peano’s space-filling curve. Historically, the revolution was forced by the discovery of mathematical structures that did not fit the patterns of Euclid and Newton. These new structures were regarded … as “pathological,” .… as a “gallery of monsters,” akin to the cubist paintings and atonal music that were upsetting established standards of taste in the arts at about the same time. The mathematicians who created the monsters regarded them as important in showing that the world of pure mathematics contains a richness of possibilities going far beyond the simple structures that they saw in Nature. Twentieth-century mathematics flowered in the belief that it had transcended completely the limitations imposed by its natural origins.
Now, as Mandelbrot points out, … Nature has played a joke on the mathematicians. The 19th-century mathematicians may not have been lacking in imagination, but Nature was not. The same pathological structures that the mathematicians invented to break loose from 19th-century naturalism turn out to be inherent in familiar objects all around us.

From the time of Aristotle it had been said that man is a social animal: that human beings naturally form communities. I couldn’t accept it. The whole of history and pre-history is against it. The two dreadful world wars we have recently been through, and the gearing of our entire economy today for defensive war belie it. Man's loathsome cruelty to man is his most outstanding characteristic; it is explicable only in terms of his carnivorous and cannibalistic origin. Robert Hartmann pointed out that both rude and civilised peoples show unspeakable cruelty to one another. We call it inhuman cruelty; but these dreadful things are unhappily truly human, because there is nothing like them in the animal world. A lion or tiger kills to eat, but the indiscriminate slaughter and calculated cruelty of human beings is quite unexampled in nature, especially among the apes. They display no hostility to man or other animals unless attacked. Even then their first reaction is to run away.

Geologists are rapidly becoming convinced that the mammals spread from their central Asian point of origin largely because of great variations in climate.

Geometric writings are not rare in which one would seek in vain for an idea at all novel, for a result which sooner or later might be of service, for anything in fact which might be destined to survive in the science; and one finds instead treatises on trivial problems or investigations on special forms which have absolutely no use, no importance, which have their origin not in the science itself but in the caprice of the author; or one finds applications of known methods which have already been made thousands of times; or generalizations from known results which are so easily made that the knowledge of the latter suffices to give at once the former. Now such work is not merely useless; it is actually harmful because it produces a real incumbrance in the science and an embarrassment for the more serious investigators; and because often it crowds out certain lines of thought which might well have deserved to be studied.

Geometry, which before the origin of things was coeternal with the divine mind and is God himself (for what could there be in God which would not be God himself?), supplied God with patterns for the creation of the world, and passed over to Man along with the image of God; and was not in fact taken in through the eyes.

He who thus considers things in their first growth and origin … will obtain the clearest view of them.

Hence when a person is in great pain, the cause of which he cannot remove, he sets his teeth firmly together, or bites some substance between them with great vehemence, as another mode of violent exertion to produce a temporary relief. Thus we have the proverb where no help can be has in pain, 'to grin and abide;' and the tortures of hell are said to be attended with 'gnashing of teeth.'Describing a suggestion of the origin of the grin in the present form of a proverb, 'to grin and bear it.'

His [Isaac Newton’s] observations of the colours of thin films [were] the origin of the next great theoretical advance, which had to await, over a hundred years, the coming of Thomas Young.

His subject is the “Origin of Species,” & not the origin of Organization; & it seems a needless mischief to have opened the latter speculation at all.

History … celebrates the battlefields that kill us, but keeps silent on the crop fields that sustain us. It knows the bastards of kings, she doesn’t know the origin of wheat. This is the way of human folly.

History warns us … that it is the customary fate of new truths to begin as heresies and to end as superstitions; and, as matters now stand, it is hardly rash to anticipate that, in another twenty years, the new generation, educated under the influences of the present day, will be in danger of accepting the main doctrines of the “Origin of Species,” with as little reflection, and it may be with as little justification, as so many of our contemporaries, twenty years ago, rejected them.

How many and how curious problems concern the commonest of the sea-snails creeping over the wet sea-weed! In how many points of view may its history be considered! There are its origin and development, the mystery of its generation, the phenomena of its growth, all concerning each apparently insignificant individual; there is the history of the species, the value of its distinctive marks, the features which link it with the higher and lower creatures, the reason why it takes its stand where we place it in the scale of creation, the course of its distribution, the causes of its diffusion, its antiquity or novelty, the mystery (deepest of mysteries) of its first appearance, the changes of the outline of continents and of oceans which have taken place since its advent, and their influence on its own wanderings.

However improbable we regard [the spontaneous origin of life],… it will almost certainly happen at least once…. The time… is of the order of two billion years.… Given so much time, the “impossible” becomes possible, the possible probable, and the probable virtually certain. One only has to wait: time itself performs the miracles.

Human blood is a testament to life’s origin in the ocean: its chemical composition is nearly identical to that of sea-water.

Human consciousness is just about the last surviving mystery. A mystery is a phenomenon that people don’t know how to think about—yet. There have been other great mysteries: the mystery of the origin of the universe, the mystery of life and reproduction, the mystery of the design to be found in nature, the mysteries of time, space, and gravity. These were not just areas of scientific ignorance, but of utter bafflement and wonder. We do not yet have the final answers to any of the questions of cosmology and particle physics, molecular genetics and evolutionary theory, but we do know how to think about them. The mysteries haven't vanished, but they have been tamed. They no longer overwhelm our efforts to think about the phenomena, because now we know how to tell the misbegotten questions from the right questions, and even if we turn out to be dead wrong about some of the currently accepted answers, we know how to go about looking for better answers. With consciousness, however, we are still in a terrible muddle. Consciousness stands alone today as a topic that often leaves even the most sophisticated thinkers tongue-tied and confused. And, as with all the earlier mysteries, there are many who insist—and hope—that there will never be a demystification of consciousness.

Human language is in some ways similar to, but in other ways vastly different from, other kinds of animal communication. We simply have no idea about its evolutionary history, though many people have speculated about its possible origins. There is, for instance, the “bow-bow” theory, that language started from attempts to imitate animal sounds. Or the “ding-dong” theory, that it arose from natural sound-producing responses. Or the “pooh-pooh” theory, that it began with violent outcries and exclamations.
We have no way of knowing whether the kinds of men represented by the earliest fossils could talk or not…
Language does not leave fossils, at least not until it has become written.

I am about to discuss the disease called “sacred”. It is not, in my opinion, any more divine or more sacred that other diseases, but has a natural cause, and its supposed divine origin is due to men's inexperience, and to their wonder at its peculiar character.

I expect to think that I would rather be author of your book [The Origin of Species] than of any other on Nat. Hist. Science.

I found the invention was applicable to painting, and would also contribute to facilitate the study of geography: for I have applied it to some maps, the rivers of which I represented in silver, and in the cities in gold. The rivers appearing, as it were, in silver streams, have a most pleasing effect on the sight, and relieve the eye of that painful search for the course, and origin, of rivers, the minutest branches of which can be splendidly represented this way.
Description of an outcome of her experiments originally investigating 'the possibility of making cloths of gold, silver and other metals by chemical processes.'

I have long held an opinion, almost amounting to conviction, in common I believe with many other lovers of natural knowledge, that the various forms under which the forces of matter are made manifest have one common origin; or, in other words, are so directly related and mutually dependent, that they are convertible, as it were, one into another, and possess equivalents of power in their action.

I hope you have not murdered too completely your own and my child.
Referring to their independently conceived ideas on the origin of species.

I intentionally left the question of the origin of life uncanvassed as being altogether ultra vires in the present state of our knowledge.

I know no study which is so unutterably saddening as that of the evolution of humanity, as it is set forth in the annals of history. Out of the darkness of prehistoric ages man emerges with the marks of his lowly origin strong upon him. He is a brute, only more intelligent than the other brutes, a blind prey to impulses, which as often as not led him to destruction; a victim to endless illusions, which make his mental existence a terror and a burden, and fill his physical life with barren toil and battle.

I see no good reason why the views given this volume [The Origin of Species] should shock the religious feelings of any one. It is satisfactory, as showing how transient such impressions are, to remember that the greatest discovery ever made by man, namely, the law of attraction of gravity, was also attacked by Leibnitz, “as subversive of natural, and inferentially of revealed, religion.”

I shall never forget the sight. The vessel of crystallization was three quarters full of slightly muddy water—that is, dilute water-glass—and from the sandy bottom there strove upwards a grotesque little landscape of variously colored growths: a confused vegetation of blue, green, and brown shoots which reminded one of algae, mushrooms, attached polyps, also moss, then mussels, fruit pods, little trees or twigs from trees, here, and there of limbs. It was the most remarkable sight I ever saw, and remarkable not so much for its profoundly melancholy nature. For when Father Leverkühn asked us what we thought of it and we timidly answered him that they might be plants: “No,” he replied, “they are not, they only act that way. But do not think the less of them. Precisely because they do, because they try as hard as they can, they are worthy of all respect.”
It turned out that these growths were entirely unorganic in their origin; they existed by virtue of chemicals from the apothecary's shop.

I think that physics is the most important—indeed the only—means we have of finding out the origins and fundamentals of our universe, and this is what interests me most about it. I believe that as science advances religion necessarily recedes, and this is a process I wish to encourage, because I consider that, on the whole, the influence of religion is malign.

I think the facts leave no doubt that the very mightiest among the chemical forces are of electric origin. The atoms cling to their electric charges, and opposite electric charges cling to each other.

I was often humiliated to see men disputing for a piece of bread, just as animals might have done. My feelings on this subject have very much altered since I have been personally exposed to the tortures of hunger. I have discovered, in fact, that a man, whatever may have been his origin, his education, and his habits, is governed, under certain circumstances, much more by his stomach than by his intelligence and his heart.

I’m trying to assemble pieces of this great jigsaw puzzle of the origin of the solar system, to see if we can illuminate our own processes on the Earth more fundamentally.

If a single cell, under appropriate conditions, becomes a man in the space of a few years, there can surely be no difficulty in understanding how, under appropriate conditions, a cell may, in the course of untold millions of years, give origin to the human race.

If Darwin had printed “The Origin of Species” as a serial running twenty or thirty years he might have found himself, at the end of it, a member of the House of Lords or even Archbishop of Canterbury. But he disgorged it in one stupendous and appalling dose, and in consequence he alarmed millions, including many of his fellow scientists, and got an evil name.

If we ever establish contact with intelligent aliens living on a planet around a distant star … They would be made of similar atoms to us. They could trace their origins back to the big bang 13.7 billion years ago, and they would share with us the universe's future. However, the surest common culture would be mathematics.

If we look round the world, there seem to be not above six distinct varieties in the human species, each of which is strongly marked, and speaks the kind seldom to have mixed with any other. But there is nothing in the shape, nothing in the faculties, that shows their coming from different originals; and the varieties of climate, of nourishment, and custom, are sufficient to produce every change.

If we turn to the problems to which the calculus owes its origin, we find that not merely, not even primarily, geometry, but every other branch of mathematical physics—astronomy, mechanics, hydrodynamics, elasticity, gravitation, and later electricity and magnetism—in its fundamental concepts and basal laws contributed to its development and that the new science became the direct product of these influences.

Immediately south of nitrogen is phosphorus, which was first isolated by the distillation and treatment of urine—an indication of the lengths to which chemists are prepared to go, or perhaps only a sign of the obsessive, scatological origins of their vocation.

In all speculations on the origin, or agents that have produced the changes on this globe, it is probable that we ought to keep within the boundaries of the probable effects resulting from the regular operations of the great laws of nature which our experience and observation have brought within the sphere of our knowledge. When we overleap those limits, and suppose a total change in nature's laws, we embark on the sea of uncertainty, where one conjecture is perhaps as probable as another; for none of them can have any support, or derive any authority from the practical facts wherewith our experience has brought us acquainted.

In its essence, the theory of natural selection is primarily an attempt to give an account of the probable mechanism of the origin of the adaptations of the organisms to their environment, and only secondarily an attempt to explain evolution at large. Some modern biologists seem to believe that the word 'adaptation' has teleological connotations, and should therefore be expunged from the scientific lexicon. With this we must emphatically disagree. That adaptations exist is so evident as to be almost a truism, although this need not mean that ours is the best of all possible worlds. A biologist has no right to close his eyes to the fact that the precarious balance between a living being and its environment must be preserved by some mechanism or mechanisms if life is to endure.

In July [1837] opened first note-book on Transmutation of Species. Had been greatly struck from about the month of previous March on character of South American fossils, and species on Galapagos Archipelago. These facts (especially latter), origin of all my views.

In less than eight years “The Origin of Species” has produced conviction in the minds of a majority of the most eminent living men of science. New facts, new problems, new difficulties as they arise are accepted, solved, or removed by this theory; and its principles are illustrated by the progress and conclusions of every well established branch of human knowledge.

In my opinion, there is absolutely no trustworthy proof that talents have been improved by their exercise through the course of a long series of generations. The Bach family shows that musical talent, and the Bernoulli family that mathematical power, can be transmitted from generation to generation, but this teaches us nothing as to the origin of such talents. In both families the high-watermark of talent lies, not at the end of the series of generations, as it should do if the results of practice are transmitted, but in the middle. Again, talents frequently appear in some member of a family which has not been previously distinguished.

In order that an inventory of plants may be begun and a classification of them correctly established, we must try to discover criteria of some sort for distinguishing what are called “species”. After a long and considerable investigation, no surer criterion for determining species had occurred to me than distinguishing features that perpetuate themselves in propagation from seed. Thus, no matter what variations occur in the individuals or the species, if they spring from the seed of one and the same plant, they are accidental variations and not such as to distinguish a species. For these variations do not perpetuate themselves in subsequent seeding. Thus, for example, we do not regard caryophylli with full or multiple blossoms as a species distinct from caryophylli with single blossoms, because the former owe their origin to the seed of the latter and if the former are sown from their own seed, they once more produce single-blossom caryophylli. But variations that never have as their source seed from one and the same species may finally be regarded as distinct species. Or, if you make a comparison between any two plants, plants which never spring from each other's seed and never, when their seed is sown, are transmuted one into the other, these plants finally are distinct species. For it is just as in animals: a difference in sex is not enough to prove a difference of species, because each sex is derived from the same seed as far as species is concerned and not infrequently from the same parents; no matter how many and how striking may be the accidental differences between them; no other proof that bull and cow, man and woman belong to the same species is required than the fact that both very frequently spring from the same parents or the same mother. Likewise in the case of plants, there is no surer index of identity of species than that of origin from the seed of one and the same plant, whether it is a matter of individuals or species. For animals that differ in species preserve their distinct species permanently; one species never springs from the seed of another nor vice versa.

In our day grand generalizations have been reached. The theory of the origin of species is but one of them. Another, of still wider grasp and more radical significance, is the doctrine of the Conservation of Energy, the ultimate philosophical issues of which are as yet but dimly seem-that doctrine which “binds nature fast in fate” to an extent not hitherto recognized, exacting from every antecedent its equivalent consequent, and bringing vital as well as physical phenomena under the dominion of that law of causal connexion which, so far as the human understanding has yet pierced, asserts itself everywhere in nature.

In reality the origin of the notion of derivatives is in the vague feeling of the mobility of things, and of the greater or less speed with which phenomena take place; this is well expressed by the terms fluent and fluxion, which were used by Newton and which we may believe were borrowed from the ancient mathematician Heraclitus.

In the distant future I see open fields for far more important researches. Psychology will be based on a new foundation, that of the necessary acquirement of each mental power and capacity by gradation. Light will be thrown on the origin of man and his history.

In the fall of 1967, [I was invited] to a conference … on pulsars. … In my talk, I argued that we should consider the possibility that the center of a pulsar is a gravitationally completely collapsed object. I remarked that one couldn't keep saying “gravitationally completely collapsed object” over and over. One needed a shorter descriptive phrase. “How about black hole?” asked someone in the audience. I had been searching for the right term for months, mulling it over in bed, in the bathtub, in my car, whenever I had quiet moments. Suddenly this name seemed exactly right. When I gave a more formal Sigma Xi-Phi Beta Kappa lecture … on December 29, 1967, I used the term, and then included it in the written version of the lecture published in the spring of 1968. (As it turned out, a pulsar is powered by “merely” a neutron star, not a black hole.)
[Although John Wheeler is often identified as coining the term “black hole,” he in fact merely popularized the expression. In his own words, this is his explanation of the true origin: a suggestion from an unidentified person in a conference audience.]

In the final, the positive, state, the mind has given over the vain search after absolute notions, the origin and destination of the universe, and the causes of phenomena, and applies itself to the study of their laws—that is, their invariable relations of succession and resemblance. Reasoning and observation, duly combined, are the means of this knowledge. What is now understood when we speak of an explanation of facts is simply the establishment of a connection between single phenomena and some general facts.

Is man a peculiar organism? Does he originate in a wholly different way from a dog, bird, frog, or fish? and does he thereby justify those who assert that he has no place in nature, and no real relationship with the lower world of animal life? Or does he develop from a similar embryo, and undergo the same slow and gradual progressive modifications? The answer is not for an instant doubtful, and has not been doubtful for the last thirty years. The mode of man’s origin and the earlier stages of his development are undoubtedly identical with those of the animals standing directly below him in the scale; without the slightest doubt, he stands in this respect nearer the ape than the ape does to the dog. (1863)

It appears that the extremely important papers that trigger a revolution may not receive a proportionately large number of citations. The normal procedures of referencing are not used for folklore. A real scientific revolution, like any other revolution, is news. The Origin of Species sold out as fast as it could be printed and was denounced from the pulpit almost immediately. Sea-floor spreading has been explained, perhaps not well, in leading newspapers, magazines, books, and most recently in a color motion picture. When your elementary school children talk about something at dinner, you rarely continue to cite it.

It feels unacceptable to many people even to think of having a cosmology based on science. … They see fanciful origin stories as spicing up the culture. … Aspects of many origin stories can enrich our understanding of the scientific picture, but they cannot take its place.

It has hitherto been a serious impediment to the progress of knowledge, that is in investigating the origin or causes of natural productions, recourse has generally been had to the examination, both by experiment and reasoning, of what might be rather than what is. The laws or processes of nature we have every reason to believe invariable. Their results from time to time vary, according to the combinations of influential circumstances; but the process remains the same. Like the poet or the painter, the chemist may, and no doubt often' does, create combinations which nature never produced; and the possibility of such and such processes giving rise to such and such results, is no proof whatever that they were ever in natural operation.

It has sometimes been said that the success of the Origin proved “that the subject was in the air,” or “that men's minds were prepared for it.” I do not think that this is strictly true, for I occasionally sounded not a few naturalists, and never happened to come across a single one who seemed to doubt about the permanence of species.

It is a vulgar belief that our astronomical knowledge dates only from the recent century when it was rescued from the monks who imprisoned Galileo; but Hipparchus…who among other achievements discovered the precession of the eqinoxes, ranks with the Newtons and the Keplers; and Copernicus, the modern father of our celestial science, avows himself, in his famous work, as only the champion of Pythagoras, whose system he enforces and illustrates. Even the most modish schemes of the day on the origin of things, which captivate as much by their novelty as their truth, may find their precursors in ancient sages, and after a careful analysis of the blended elements of imagination and induction which charaterise the new theories, they will be found mainly to rest on the atom of Epicurus and the monad of Thales. Scientific, like spiritual truth, has ever from the beginning been descending from heaven to man.

It is easy to create an interstellar radio message which can be recognized as emanating unambiguously from intelligent beings. A modulated signal (‘beep,’ ‘beep-beep,’…) comprising the numbers 1, 2, 3, 5, 7, 11, 13, 17, 19, 23, 29, 31, for example, consists exclusively of the first 12 prime numbers…. A signal of this kind, based on a simple mathematical concept, could only have a biological origin. … But by far the most promising method is to send pictures.

It is in scientific honesty that I endorse the presentation of alternative theories for the origin of the universe, life and man in the science classroom. It would be an error to overlook the possibility that the universe was planned rather than happening by chance.

It is mere rubbish thinking, at present, of origin of life; one might as well think of origin of matter.

It is no valid objection that science as yet throws no light on the far higher problem of the essence or origin of life. Who can explain gravity? No one now objects to following out the results consequent on this unknown element of attraction...

It is often assumed that because the young child is not competent to study geometry systematically he need be taught nothing geometrical; that because it would be foolish to present to him physics and mechanics as sciences it is useless to present to him any physical or mechanical principles.
An error of like origin, which has wrought incalculable mischief, denies to the scholar the use of the symbols and methods of algebra in connection with his early essays in numbers because, forsooth, he is not as yet capable of mastering quadratics! … The whole infant generation, wrestling with arithmetic, seek for a sign and groan and travail together in pain for the want of it; but no sign is given them save the sign of the prophet Jonah, the withered gourd, fruitless endeavor, wasted strength.

It is therefore proper to acknowledge that the first filaments of the chick preexist in the egg and have a deeper origin, exactly as [the embryo] in the eggs of plants.

It is well to observe the force and virtue and consequence of discoveries, and these are to be seen nowhere more conspicuously than in those three which were unknown to the ancients, and of which the origins, although recent, are obscure and inglorious; namely, printing, gunpowder, and the magnet. For these three have changed the whole face and state of things throughout the world; the first in literature, the second in warfare, the third in navigation; whence have followed innumerable changes, insomuch that no empire, no sect, no star seems to have exerted greater power and influence in human affairs than these mechanical discoveries.

It must have appeared almost as improbable to the earlier geologists, that the laws of earthquakes should one day throw light on the origin of mountains, as it must to the first astronomers, that the fall of an apple should assist in explaining the motions of the moon.

It need scarcely be pointed out that with such a mechanism complete isolation of portion of a species should result relatively rapidly in specific differentiation, and one that is not necessarily adaptive. The effective inter­group competition leading to adaptive advance may be between species rather than races. Such isolation is doubtless usually geographic in character at the outset but may be clinched by the development of hybrid sterility. The usual difference of the chromosome complements of related species puts the importance of chromosome aberration as an evolutionary process beyond question, but, as I see it, this importance is not in the character differences which they bring (slight in balanced types), but rather in leading to the sterility of hybrids and thus making permanent the isolation of two groups.
How far do the observations of actual species and their subdivisions conform to this picture? This is naturally too large a subject for more than a few suggestions.
That evolution involves non-adaptive differentiation to a large extent at the subspecies and even the species level is indicated by the kinds of differences by which such groups are actually distinguished by systematics. It is only at the subfamily and family levels that clear-cut adaptive differences become the rule. The principal evolutionary mechanism in the origin of species must thus be an essentially nonadaptive one.

It was through living among these groups and much more I think, through moving regularly from one to the other and back again that I got occupied with the problem of what, long before I put it on paper, I christened to myself as the ‘two cultures’. For constantly I felt I was moving among two groups [scientists and literary intellectuals] comparable in intelligence, identical in race, not grossly different in social origin, earning about the same incomes, who had almost ceased to communicate at all, who in intellectual, moral and psychological climate had so little in common that instead of going from Burlington House or South Kensington to Chelsea, one might have crossed an ocean.

It wasn’t the finches that put the idea [of natural selection] in Darwin’s head, it was the tortoises. The reason he didn’t use the tortoises [in writing On the Origin of Species] was that, when he got back, he found he didn’t have localities on the tortoise specimens. Here the great god, the greatest naturalist we have records of, made a mistake. His fieldwork wasn’t absolutely perfect.

It will be found that everything depends on the composition of the forces with which the particles of matter act upon one another; and from these forces, as a matter of fact, all phenomena of Nature take their origin.

It will be possible, through the detailed determination of amino-acid sequences of hemoglobin molecules and of other molecules too, to obtain much information about the course of the evolutionary process, and to illuminate the question of the origin of species.

Just as in the animal and vegetable kingdoms, an individual comes into being, so to speak, grows, remains in being, declines and passes on, will it not be the same for entire species? If our faith did not teach us that animals left the Creator's hands just as they now appear and, if it were permitted to entertain the slightest doubt as to their beginning and their end, may not a philosopher, left to his own conjectures, suspect that, from time immemorial, animal life had its own constituent elements, scattered and intermingled with the general body of matter, and that it happened when these constituent elements came together because it was possible for them to do so; that the embryo formed from these elements went through innumerable arrangements and developments, successively acquiring movement, feeling, ideas, thought, reflection, consciousness, feelings, emotions, signs, gestures, sounds, articulate sounds, language, laws, arts and sciences; that millions of years passed between each of these developments, and there may be other developments or kinds of growth still to come of which we know nothing; that a stationary point either has been or will be reached; that the embryo either is, or will be, moving away from this point through a process of everlasting decay, during which its faculties will leave it in the same way as they arrived; that it will disappear for ever from nature-or rather, that it will continue to exist there, but in a form and with faculties very different from those it displays at this present point in time? Religion saves us from many deviations, and a good deal of work. Had religion not enlightened us on the origin of the world and the universal system of being, what a multitude of different hypotheses we would have been tempted to take as nature's secret! Since these hypotheses are all equally wrong, they would all have seemed almost equally plausible. The question of why anything exists is the most awkward that philosophy can raise- and Revelation alone provides the answer.

Know, oh Brother (May God assist thee and us by the Spirit from Him) that God, Exalted Be His Praise, when He created all creatures and brought all things into being, arranged them and brought them into existence by a process similar to the process of generation of numbers from one, so that the multiplicity [of numbers] should be a witness to his Oneness, and their classification and order an indication of the perfection of His wisdom in creation. And this would be a witness to the fact, too, that they [creatures] are related to Him who created them, in the same way as the numbers are related to the One which is prior to two, and which is the principle, origin and source of numbers, as we have shown in our treatise on arithmetic.

Life through many long periods has been manifested in a countless host of varying structures, all circumscribed by one general plan, each appointed to a definite place, and limited to an appointed duration. On the whole the earth has been thus more and more covered by the associated life of plants and animals, filling all habitable space with beings capable of enjoying their own existence or ministering to the enjoyment of others; till finally, after long preparation, a being was created capable of the wonderful power of measuring and weighing all the world of matter and space which surrounds him, of treasuring up the past history of all the forms of life, and considering his own relation to the whole. When he surveys this vast and co-ordinated system, and inquires into its history and origin, can he be at a loss to decide whether it be a work of Divine thought and wisdom, or the fortunate offspring of a few atoms of matter, warmed by the anima mundi, a spark of electricity, or an accidental ray of sunshine?

Man is no new-begot child of the ape, bred of a struggle for existence upon brutish lines—nor should the belief that such is his origin, oft dinned into his ears by scientists, influence his conduct. Were he to regard himself as an extremely ancient type, distinguished chiefly by the qualities of his mind, and to look upon the existing Primates as the failures of his line, as his misguided and brutish collaterals, rather than as his ancestors, I think it would be something gained for the ethical outlook of Homo—and also it would be consistent with present knowledge.

Man may be excused for feeling some pride at having risen, though not through his own exertions, to the very summit of the organic scale; and the fact of his having thus risen, instead of having been aboriginally placed there, may give him hopes for a still higher destiny in the distant future. But we are not here concerned with hopes or fears, only with the truth as far as our reason allows us to discover it. I have given the evidence to the best of my ability; and we must acknowledge, as it seems to me, that man with all his noble qualities, with sympathy which feels for the most debased, with benevolence which extends not only to other men but to the humblest living creature, with his god-like intellect which has penetrated into the movements and constitution of the solar system—with all these exalted powers—Man still bears in his bodily frame the indelible stamp of his lowly origin.

Mathematics as a science commenced when first someone, probably a Greek, proved propositions about any things or about some things, without specification of definite particular things. These propositions were first enunciated by the Greeks for geometry; and, accordingly, geometry was the great Greek mathematical science.

Melvin Calvin was a fearless scientist, totally unafraid to venture into new fields such as hot atom chemistry, carcinogenesis, chemical evolution and the origin of life, organic geochemistry, immunochemistry, petroleum production from plants, farming, Moon rock analysis, and development of novel synthetic biomembrane models for plant photosystems.