At the origin, the [space travel] pioneers of the greatest adventure of all times were motivated by the drive to explore, by the pure spirit of conquest, by the lofty desire to open up new fields to human genius. … From their exceptional journeys, they all came back with the revelation of beauty. Beauty of the black sky, beauty and variety of our planet, beauty of the Earth seen from the Moon, girdled by a scintillating belt of equatorial thunderstorms. They all emphasize that our planet is one, that borderlines are artificial, that humankind is one single community on board spaceship Earth. They all insist that this fragile gem is at our mercy and that we must all endeavor to protect it.

For just as musical instruments are brought to perfection of clearness in the sound of their strings by means of bronze plates or horn sounding boards, so the ancients devised methods of increasing the power of the voice in theaters through the application of the science of harmony.

I can see him [Sylvester] now, with his white beard and few locks of gray hair, his forehead wrinkled o’er with thoughts, writing rapidly his figures and formulae on the board, sometimes explaining as he wrote, while we, his listeners, caught the reflected sounds from the board. But stop, something is not right, he pauses, his hand goes to his forehead to help his thought, he goes over the work again, emphasizes the leading points, and finally discovers his difficulty. Perhaps it is some error in his figures, perhaps an oversight in the reasoning. Sometimes, however, the difficulty is not elucidated, and then there is not much to the rest of the lecture. But at the next lecture we would hear of some new discovery that was the outcome of that difficulty, and of some article for the Journal, which he had begun. If a text-book had been taken up at the beginning, with the intention of following it, that text-book was most likely doomed to oblivion for the rest of the term, or until the class had been made listeners to every new thought and principle that had sprung from the laboratory of his mind, in consequence of that first difficulty. Other difficulties would soon appear, so that no text-book could last more than half of the term. In this way his class listened to almost all of the work that subsequently appeared in the Journal. It seemed to be the quality of his mind that he must adhere to one subject. He would think about it, talk about it to his class, and finally write about it for the Journal. The merest accident might start him, but once started, every moment, every thought was given to it, and, as much as possible, he read what others had done in the same direction; but this last seemed to be his real point; he could not read without finding difficulties in the way of understanding the author. Thus, often his own work reproduced what had been done by others, and he did not find it out until too late.
A notable example of this is in his theory of cyclotomic functions, which he had reproduced in several foreign journals, only to find that he had been greatly anticipated by foreign authors. It was manifest, one of the critics said, that the learned professor had not read Rummer’s elementary results in the theory of ideal primes. Yet Professor Smith’s report on the theory of numbers, which contained a full synopsis of Kummer’s theory, was Professor Sylvester’s constant companion.
This weakness of Professor Sylvester, in not being able to read what others had done, is perhaps a concomitant of his peculiar genius. Other minds could pass over little difficulties and not be troubled by them, and so go on to a final understanding of the results of the author. But not so with him. A difficulty, however small, worried him, and he was sure to have difficulties until the subject had been worked over in his own way, to correspond with his own mode of thought. To read the work of others, meant therefore to him an almost independent development of it. Like the man whose pleasure in life is to pioneer the way for society into the forests, his rugged mind could derive satisfaction only in hewing out its own paths; and only when his efforts brought him into the uncleared fields of mathematics did he find his place in the Universe.

If gold medals and prizes were awarded to institutions instead of individuals, the Peter Bent Brigham Hospital of 30 years ago would have qualified. The ruling board and administrative structure of that hospital did not falter in their support of the quixotic objective of treating end-stage renal disease despite a long list of tragic failures that resulted from these early efforts.

In the medical field [scientific ignorance] could lead to horrendous results. People who don’t understand the difference between a controlled experiment and claims by some quack may die as a result of not taking medical science seriously. One of the most damaging examples of pseudoscience is false memory syndrome. I’m on the board of a foundation exposing this problem.

It is impossible to imagine the universe run by a wise, just and omnipotent God, but it is quite easy to imagine it run by a board of gods. If such a board actually exists it operates precisely like the board of a corporation that is losing money.

Leibnitz believed he saw the image of creation in his binary arithmetic in which he employed only two characters, unity and zero. Since God may be represented by unity, and nothing by zero, he imagined that the Supreme Being might have drawn all things from nothing, just as in the binary arithmetic all numbers are expressed by unity with zero. This idea was so pleasing to Leibnitz, that he communicated it to the Jesuit Grimaldi, President of the Mathematical Board of China, with the hope that this emblem of the creation might convert to Christianity the reigning emperor who was particularly attached to the sciences.

One should drill the hole where the board is thickest.

The game of chess has always fascinated mathematicians, and there is reason to suppose that the possession of great powers of playing that game is in many features very much like the possession of great mathematical ability. There are the different pieces to learn, the pawns, the knights, the bishops, the castles, and the queen and king. The board possesses certain possible combinations of squares, as in rows, diagonals, etc. The pieces are subject to certain rules by which their motions are governed, and there are other rules governing the players. … One has only to increase the number of pieces, to enlarge the field of the board, and to produce new rules which are to govern either the pieces or the player, to have a pretty good idea of what mathematics consists.

They think that differential equations are not reality. Hearing some colleagues speak, it’s as though theoretical physics was just playing house with plastic building blocks. This absurd idea has gained currency, and now people seem to feel that theoretical physicists are little more than dreamers locked away ivory towers. They think our games, our little houses, bear no relation to their everyday worries, their interests, their problems, or their welfare. But I’m going to tell you something, and I want you to take it as a ground rule for this course. From now on I will be filling this board with equations. … And when I'm done, I want you to do the following: look at those numbers, all those little numbers and Greek letters on the board, and repeat to yourselves, “This is reality,” repeat it over and over.

Water, water everywhere,
And how the boards did shrink.
Water, water everywhere,
Nor any drop to drink.

Whenever I get gloomy with the state of the world, I think about the arrivals gate at Heathrow Airport. General opinion’s starting to make out that we live in a world of hatred and greed, but I don’t see that. It seems to me that love is everywhere. Often it’s not particularly dignified or newsworthy, but it’s always there - fathers and sons, mothers and daughters, husbands and wives, boyfriends, girlfriends, old friends. When the planes hit the Twin Towers, as far as I know none of the phone calls from the people on board were messages of hate or revenge - they were all messages of love. If you look for it, I’ve got a sneaky feeling you’ll find that love actually is all around.

Wilderness is an anchor to windward. Knowing it is there, we can also know that we are still a rich nation, tending our resources as we should—not a people in despair searching every last nook and cranny of our land for a board of lumber, a barrel of oil, a blade of grass, or a tank of water.