[S]uppose you make a hole in an ordinary evacuated electric light bulb and allow the air molecules to pass in at the rate of 1,000,000 a second, the bulb will become full of air in approximately 100,000,000 years.

[Why people buy quarter-inch drill bits.] They don't want quarter-inch bits. They want quarter-inch holes.

A proposal…to bore a hole in the crust of the Earth and discover the conditions deep down below the surface…may remind us that the most secret places of Nature are, perhaps, not 10 to the n-th miles above our heads, but 10 miles below our feet.

Common sense iz instinkt, and instinkt don’t make enny blunders mutch, no more than a rat duz, in coming out, or going intew a hole, he hits the hole the fust time, and just fills it.

Consider a cow. A cow doesn’t have the problem-solving skill of a chimpanzee, which has discovered how to get termites out of the ground by putting a stick into a hole. Evolution has developed the brain’s ability to solve puzzles, and at the same time has produced in our brain a pleasure of solving problems.

Dr. Walter Baade of Mount Wilson Observatory facetiously accused the present generation of Milky Way astronomers of not having looked sufficiently far beyond our “local swimming hole”.

Exper. I. I made a small hole in a window-shutter, and covered it with a piece of thick paper, which I perforated with a fine needle. For greater convenience of observation I placed a small looking-glass without the window-shutter, in such a position as to reflect the sun's light, in a direction nearly horizontal, upon the opposite wall, and to cause the cone of diverging light to pass over a table on which were several little screens of card-paper. I brought into the sunbeam a slip of card, about one-thirtieth of an inch in breadth, and observed its shadow, either on the wall or on other cards held at different distances. Besides the fringes of colour on each side of the shadow, the shadow itself was divided by similar parallel fringes, of smaller dimensions, differing in number, according to the distance at which the shadow was observed, but leaving the middle of the shadow always white. Now these fringes were the joint effects of the portions of light passing on each side of the slip of card and inflected, or rather diffracted, into the shadow. For, a little screen being placed a few inches from the card, so as to receive either edge of the shadow on its margin, all the fringes which had before been observed in the shadow on the wall, immediately disappeared, although the light inflected on the other side was allowed to retain its course, and although this light must have undergone any modification that the proximity of the other edge of the slip of card might have been capable of occasioning... Nor was it for want of a sufficient intensity of light that one of the two portions was incapable of producing the fringes alone; for when they were both uninterrupted, the lines appeared, even if the intensity was reduced to one-tenth or one-twentieth.

For terrestrial vertebrates, the climate in the usual meteorological sense of the term would appear to be a reasonable approximation of the conditions of temperature, humidity, radiation, and air movement in which terrestrial vertebrates live. But, in fact, it would be difficult to find any other lay assumption about ecology and natural history which has less general validity. … Most vertebrates are much smaller than man and his domestic animals, and the universe of these small creatures is one of cracks and crevices, holes in logs, dense underbrush, tunnels, and nests—a world where distances are measured in yards rather than miles and where the difference between sunshine and shadow may be the difference between life and death. Actually, climate in the usual sense of the term is little more than a crude index to the physical conditions in which most terrestrial animals live.

Here’s to the crazy ones. The misfits. The rebels. The troublemakers. The round heads in the square holes. The ones who see things differently. They’re not fond of rules. You can quote them. Disagree with them. Glorify or vilify them. But the only thing you can’t do is ignore them. Because they change things. They push the human race forward. And while some may see them as the crazy ones, we see genius. Because the people who are crazy enough to think they can change the world, are the ones who do.

It is said that the composing of the Lilavati was occasioned by the following circumstance. Lilavati was the name of the author’s daughter, concerning whom it appeared, from the qualities of the ascendant at her birth, that she was destined to pass her life unmarried, and to remain without children. The father ascertained a lucky hour for contracting her in marriage, that she might be firmly connected and have children. It is said that when that hour approached, he brought his daughter and his intended son near him. He left the hour cup on the vessel of water and kept in attendance a time-knowing astrologer, in order that when the cup should subside in the water, those two precious jewels should be united. But, as the intended arrangement was not according to destiny, it happened that the girl, from a curiosity natural to children, looked into the cup, to observe the water coming in at the hole, when by chance a pearl separated from her bridal dress, fell into the cup, and, rolling down to the hole, stopped the influx of water. So the astrologer waited in expectation of the promised hour. When the operation of the cup had thus been delayed beyond all moderate time, the father was in consternation, and examining, he found that a small pearl had stopped the course of the water, and that the long-expected hour was passed. In short, the father, thus disappointed, said to his unfortunate daughter, I will write a book of your name, which shall remain to the latest times—for a good name is a second life, and the ground-work of eternal existence.

One should drill the hole where the board is thickest.

Scientists often invent words to fill the holes in their understanding.These words are meant as conveniences until real understanding can be found. … Words such as dimension and field and infinity … are not descriptions of reality, yet we accept them as such because everyone is sure someone else knows what the words mean.

Shoe leather epidemiology.
[Langmuir stressed that investigators go into the field to collect their own data and directly view the locale of a public health problem. His graduates wore lapel pins of a shoe with a hole in the sole.]

The Humorless Person: I have a friend who has about as much sense of humor as the wooden Indian of commerce. Some time ago he made a trip through the Mammoth Cave of Kentucky. … He did his sight-seeing very thoroughly. He didn’t miss a single ramification in that great crack in the face of Mother Nature. … I asked him what he thought of the Mammoth Cave. “Well,” said he, “taking it as a hole, it is all right.”

The secular world is full of holes. We have secularized badly.

To the east was our giant neighbor Makalu, unexplored and unclimbed, and even on top of Everest the mountaineering instinct was sufficient strong to cause me to spend some moments conjecturing as to whether a route up that mountain might not exist. Far away across the clouds the great bulk of Kangchenjunga loomed on the horizon. To the west, Cho Oyu, our old adversary from 1952, dominated the scene and we could see the great unexplored ranges of Nepal stretching off into the distance. The most important photograph, I felt, was a shot down the north ridge, showing the North Col and the old route that had been made famous by the struggles of those great climbers of the 1920s and 1930s. I had little hope of the results being particularly successful, as I had a lot of difficulty in holding the camera steady in my clumsy gloves, but I felt that they would at least serve as a record. After some ten minutes of this, I realized that I was becoming rather clumsy-fingered and slow-moving, so I quickly replaced my oxygen set and experience once more the stimulating effect of even a few liters of oxygen. Meanwhile, Tenzing had made a little hole in the snow and in it he placed small articles of food – a bar of chocolate, a packet of biscuits and a handful of lollies. Small offerings, indeed, but at least a token gifts to the gods that all devoted Buddhists believe have their home on this lofty summit. While we were together on the South Col two days before, Hunt had given me a small crucifix that he had asked me to take to the top. I, too, made a hole in the snow and placed the crucifix beside Tenzing’s gifts.

Whether you take the doughnut hole as a blank space or as an entity unto itself is a purely metaphysical question and does not affect the taste of the doughnut one bit.