...while science gives us implements to use, science alone does not determine for what ends they will be employed. Radio is an amazing invention. Yet now that it is here, one suspects that Hitler never could have consolidated his totalitarian control over Germany without its use. One never can tell what hands will reach out to lay hold on scientific gifts, or to what employment they will be put. Ever the old barbarian emerges, destructively using the new civilization.

“Daddy,” she says, “which came first, the chicken or the egg?”
Steadfastly, even desperately, we have been refusing to commit ourselves. But our questioner is insistent. The truth alone will satisfy her. Nothing less. At long last we gather up courage and issue our solemn pronouncement on the subject: “Yes!”
So it is here.
“Daddy, is it a wave or a particle?”
“Yes.”
“Daddy, is the electron here or is it there?”
“Yes.”
“Daddy, do scientists really know what they are talking about?”
“Yes!”

[At DuPont,] I was very fortunate that I worked under men who were very much interested in making discoveries and inventions. They were very much interested in what they were doing, and they left me alone. And I was able to experiment on my own, and I found this very stimulating. It appealed to the creative person in me.

[Before the time of Benjamin Peirce it never occurred to anyone that mathematical research] was one of the things for which a mathematical department existed. Today it is a commonplace in all the leading universities. Peirce stood alone—a mountain peak whose absolute height might be hard to measure, but which towered above all the surrounding country.

[Engineers are] the direct and necessary instrument of coalition by which alone the new social order can commence.

[First use of the term science fiction:] We hope it will not be long before we may have other works of Science-Fiction [like Richard Henry Horne's The Poor Artist], as we believe such books likely to fulfil a good purpose, and create an interest, where, unhappily, science alone might fail.
[Thomas] Campbell says, that “Fiction in Poetry is not the reverse of truth, but her soft and enchanting resemblance.” Now this applies especially to Science-Fiction, in which the revealed truths of Science may be given interwoven with a pleasing story which may itself be poetical and true—thus circulating a knowledge of Poetry of Science, clothed in a garb of the Poetry of life.

[I]t is truth alone—scientific, established, proved, and rational truth—which is capable of satisfying nowadays the awakened minds of all classes. We may still say perhaps, 'faith governs the world,'—but the faith of the present is no longer in revelation or in the priest—it is in reason and in science.

[The religion of science was] an implicit faith that by the methods of physical science, and by these methods alone, could be solved all the problems arising out of the relation of man to man and of man towards the universe.

[The sun] … which alone we should judge to be worthy of the most high God, if He should be pleased with a material domicile, and choose a place in which to dwell with the blessed angels.

[Writing this letter] has permitted me, for a moment, to abstract myself from the dry and dreary waste of politics, into which I have been impressed by the times on which I happened, and to indulge in the rich fields of nature, where alone I should have served as a volunteer, if left to my natural inclinations and partialties.

Ode to The Amoeba
Recall from Time's abysmal chasm
That piece of primal protoplasm
The First Amoeba, strangely splendid,
From whom we're all of us descended.
That First Amoeba, weirdly clever,
Exists today and shall forever,
Because he reproduced by fission;
He split himself, and each division
And subdivision deemed it fitting
To keep on splitting, splitting, splitting;
So, whatsoe'er their billions be,
All, all amoebas still are he.
Zoologists discern his features
In every sort of breathing creatures,
Since all of every living species,
No matter how their breed increases
Or how their ranks have been recruited,
From him alone were evoluted.
King Solomon, the Queen of Sheba
And Hoover sprang from that amoeba;
Columbus, Shakespeare, Darwin, Shelley
Derived from that same bit of jelly.
So famed is he and well-connected,
His statue ought to be erected,
For you and I and William Beebe
Are undeniably amoebae!

The Mighty Task is Done

At last the mighty task is done;
Resplendent in the western sun
The Bridge looms mountain high;
Its titan piers grip ocean floor,
Its great steel arms link shore with shore,
Its towers pierce the sky.

On its broad decks in rightful pride,
The world in swift parade shall ride,
Throughout all time to be;
Beneath, fleet ships from every port,
Vast landlocked bay, historic fort,
And dwarfing all the sea.

To north, the Redwood Empires gates;
To south, a happy playground waits,
In Rapturous appeal;
Here nature, free since time began,
Yields to the restless moods of man,
Accepts his bonds of steel.

Launched midst a thousand hopes and fears,
Damned by a thousand hostile sneers,
Yet Neer its course was stayed,
But ask of those who met the foe
Who stood alone when faith was low,
Ask them the price they paid.

Ask of the steel, each strut and wire,
Ask of the searching, purging fire,
That marked their natal hour;
Ask of the mind, the hand, the heart,
Ask of each single, stalwart part,
What gave it force and power.

An Honored cause and nobly fought
And that which they so bravely wrought,
Now glorifies their deed,
No selfish urge shall stain its life,
Nor envy, greed, intrigue, nor strife,
Nor false, ignoble creed.

High overhead its lights shall gleam,
Far, far below lifes restless stream,
Unceasingly shall flow;
For this was spun its lithe fine form,
To fear not war, nor time, nor storm,
For Fate had meant it so.

Nicht Kunst und Wissenschaft allein,
Geduld will bei dem Werke sein.
Not Art and Science serve alone; Patience must in the work be shown.

Omnes scientiae sunt connexae et fovent auxiliis sicut partes ejusdem totius, quarum quaelibet opus suum peragit non propter se sed pro aliis.
All sciences are connected; they lend each other material aid as parts of one great whole, each doing its own work, not for itself alone, but for the other parts; as the eye guides the body and the foot sustains it and leads it from place to place.

~~[False Attribution]~~ Sometimes I think we’re alone in the universe, and sometimes I think we’re not. In either case, the idea is quite staggering.

A human being should be able to change a diaper, plan an invasion, butcher a hog, conn a ship, design a building, write a sonnet, balance accounts, build a wall, set a bone, comfort the dying, take orders, give orders, cooperate, act alone, solve equations, analyze a new problem, pitch manure, program a computer, cook a tasty meal, fight efficiently, die gallantly. Specialization is for insects.

A multidisciplinary study group ... estimated that it would be 1980 before developments in artificial intelligence make it possible for machines alone to do much thinking or problem solving of military significance. That would leave, say, five years to develop man-computer symbiosis and 15 years to use it. The 15 may be 10 or 500, but those years should be intellectually the most creative and exciting in the history of mankind.

A person is smart. People are dumb ... Fifteen hundred years ago everybody knew the Earth was the center of the universe. Five hundred years ago, everybody knew the Earth was flat, and fifteen minutes ago, you knew that humans were alone on this planet. Imagine what you'll know tomorrow.

A physician’s subject of study is necessarily the patient, and his first field for observation is the hospital. But if clinical observation teaches him to know the form and course of diseases, it cannot suffice to make him understand their nature; to this end he must penetrate into the body to find which of the internal parts are injured in their functions. That is why dissection of cadavers and microscopic study of diseases were soon added to clinical observation. But to-day these various methods no longer suffice; we must push investigation further and, in analyzing the elementary phenomena of organic bodies, must compare normal with abnormal states. We showed elsewhere how incapable is anatomy alone to take account of vital phenenoma, and we saw that we must add study of all physico-chemical conditions which contribute necessary elements to normal or pathological manifestations of life. This simple suggestion already makes us feel that the laboratory of a physiologist-physician must be the most complicated of all laboratories, because he has to experiment with phenomena of life which are the most complex of all natural phenomena.

Adrenalin does not excite sympathetic ganglia when applied to them directly, as does nicotine. Its effective action is localised at the periphery. The existence upon plain muscle of a peripheral nervous network, that degenerates only after section of both the constrictor and inhibitory nerves entering it, and not after section of either alone, has been described. I find that even after such complete denervation, whether of three days' or ten months' duration, the plain muscle of the dilatator pupillae will respond to adrenalin, and that with greater rapidity and longer persistence than does the iris whose nervous relations are uninjured. Therefore it cannot be that adrenalin excites any structure derived from, and dependent for its persistence on, the peripheral neurone. But since adrenalin does not evoke any reaction from muscle that has at no time of its life been innervated by the sympathetic, the point at which the stimulus of the chemical excitant is received, and transformed into what may cause the change of tension of the muscle fibre, is perhaps a mechanism developed out of the muscle cell in response to its union with the synapsing sympathetic fibre, the function of which is to receive and transform the nervous impulse. Adrenalin might then be the chemical stimulant liberated on each occasion when the impulse arrives at the periphery.

After I had addressed myself to this very difficult and almost insoluble problem, the suggestion at length came to me how it could be solved with fewer and much simpler constructions than were formerly used, if some assumptions (which are called axioms) were granted me. They follow in this order.
There is no one center of all the celestial circles or spheres.
The center of the earth is not the center of the universe, but only of gravity and of the lunar sphere.
All the spheres revolve about the sun as their mid-point, and therefore the sun is the center of the universe.
The ratio of the earth’s distance from the sun to the height of the firmament is so much smaller than the ratio of the earth’s radius to its distance from the sun that the distance from the earth to the sun is imperceptible in comparison with the height of the firmament.
Whatever motion appears in the firmament arises not from any motion of the firmament, but from the earth’s motion. The earth together with its circumjacent elements performs a complete rotation on its fixed poles in a daily motion, while the firmament and highest heaven abide unchanged.
What appears to us as motions of the sun arise not from its motion but from the motion of the earth and our sphere, with which we revolve about the sun like any other planet. The earth has, then, more than one motion.
The apparent retrograde and direct motion of the planets arises not from their motion but from the earth’s. The motion of the earth alone, therefore, suffices to explain so many apparent inequalities in the heavens.

Alcmaeon was the first to define the difference between man and animals, saying that man differs from the latter in the fact that he alone has the power of understanding.

All other things have a portion of everything, but Mind is infinite and self-ruled, and is mixed with nothing but is all alone by itself.

All the human culture, all the results of art, science and technology that we see before us today, are almost exclusively the creative product of the Aryan. This very fact admits of the not unfounded inference that he alone was the founder of all higher humanity, therefore representing the prototype of all that we understand by the word 'man.' He is the Prometheus of mankind from whose shining brow the divine spark of genius has sprung at all times, forever kindling anew that fire of knowledge which illuminated the night of silent mysteries and thus caused man to climb the path to mastery over the other beings of the earth ... It was he who laid the foundations and erected the walls of every great structure in human culture.

All things appear and disappear because of the concurrence of causes and conditions. Nothing ever exists entirely alone; everything is in relationship to everything else.

Among all highly civilized peoples the golden age of art has always been closely coincident with the golden age of the pure sciences, particularly with mathematics, the most ancient among them.
This coincidence must not be looked upon as accidental, but as natural, due to an inner necessity. Just as art can thrive only when the artist, relieved of the anxieties of existence, can listen to the inspirations of his spirit and follow in their lead, so mathematics, the most ideal of the sciences, will yield its choicest blossoms only when life’s dismal phantom dissolves and fades away, when the striving after naked truth alone predominates, conditions which prevail only in nations while in the prime of their development.

An engineer, a physicist and a mathematician find themselves in an anecdote, indeed an anecdote quite similar to many that you have no doubt already heard.
After some observations and rough calculations the engineer realizes the situation and starts laughing.
A few minutes later the physicist understands too and chuckles to himself happily, as he now has enough experimental evidence to publish a paper.
This leaves the mathematician somewhat perplexed, as he had observed right away that he was the subject of an anecdote, and deduced quite rapidly the presence of humor from similar anecdotes, but considers this anecdote to be too trivial a corollary to be significant, let alone funny.

Anaxagoras of Clazomenae, son of Hegesiboulos, held that the first principles of things were the homoeomeries. For it seemed to him quite impossible that anything should come into being from the non-existent or be dissolved into it. Anyhow we take in nourishment which is simple and homogeneous, such as bread or water, and by this are nourished hair, veins, arteries, flesh, sinews, bones and all the other parts of the body. Which being so, we must agree that everything that exists is in the nourishment we take in, and that everything derives its growth from things that exist. There must be in that nourishment some parts that are productive of blood, some of sinews, some of bones, and so on-parts which reason alone can apprehend. For there is no need to refer the fact that bread and water produce all these things to sense-perception; rather, there are in bread and water parts which only reason can apprehend.

And from my pillow, looking forth by light
Of moon or favouring stars, I could behold
The antechapel where the statue stood
Of Newton with his prism and silent face,
The marble index of a mind for ever
Voyaging through strange seas of Thought, alone.

And from this such small difference of eight minutes [of arc] it is clear why Ptolemy, since he was working with bisection [of the linear eccentricity], accepted a fixed equant point… . For Ptolemy set out that he actually did not get below ten minutes [of arc], that is a sixth of a degree, in making observations. To us, on whom Divine benevolence has bestowed the most diligent of observers, Tycho Brahe, from whose observations this eight-minute error of Ptolemy’s in regard to Mars is deduced, it is fitting that we accept with grateful minds this gift from God, and both acknowledge and build upon it. So let us work upon it so as to at last track down the real form of celestial motions (these arguments giving support to our belief that the assumptions are incorrect). This is the path I shall, in my own way, strike out in what follows. For if I thought the eight minutes in [ecliptic] longitude were unimportant, I could make a sufficient correction (by bisecting the [linear] eccentricity) to the hypothesis found in Chapter 16. Now, because they could not be disregarded, these eight minutes alone will lead us along a path to the reform of the whole of Astronomy, and they are the matter for a great part of this work.

And new philosophy calls all in doubt,
The Element of fire is quite put out;
The Sun is lost, and th’earth, and no mans wit
Can well direct him where to look for it.
And freely men confesse that this world’s spent,
When in the Planets, and the Firmament
They seeke so many new; and then see that this
Is crumbled out againe to his Atomies.
’Tis all in pieces, all cohaerence gone;
All just supply, and all Relation;
Prince, Subject, Father, Sonne, are things forgot,
For every man alone thinkes he hath got
To be a phoenix, and that then can bee
None of that kinde, of which he is, but hee.

And thus Nature will be very conformable to her self and very simple, performing all the great Motions of the heavenly Bodies by the Attraction of Gravity which intercedes those Bodies, and almost all the small ones of their Particles by some other attractive and repelling Powers which intercede the Particles. The Vis inertiae is a passive Principle by which Bodies persist in their Motion or Rest, receive Motion in proportion to the Force impressing it, and resist as much as they are resisted. By this Principle alone there never could have been any Motion in the World. Some other Principle was necessary for putting Bodies into Motion; and now they are in Motion, some other Principle is necessary for conserving the Motion.

Another great and special excellence of mathematics is that it demands earnest voluntary exertion. It is simply impossible for a person to become a good mathematician by the happy accident of having been sent to a good school; this may give him a preparation and a start, but by his own individual efforts alone can he reach an eminent position.

Are you aware that humanity is just a blip? Not even a blip. Just a fraction of a fraction of what the universe has been and will become? Talk about perspective. I figure I can’t feel so entirely stupid about saying what I said because, first of all, it’s true. And second of all, there will be no remnant of me or my stupidity. No fossil or geographical shift that can document, really, even the most important historical human beings, let alone my paltry admissions.

Aristotle ... imputed this symphony of the heavens ... this music of the spheres to Pythagorus. ... But Pythagoras alone of mortals is said to have heard this harmony ... If our hearts were as pure, as chaste, as snowy as Pythagoras' was, our ears would resound and be filled with that supremely lovely music of the wheeling stars.

Armed with all the powers, enjoying all the wealth they owe to science, our societies are still trying to practice and to teach systems of values already destroyed at the roots by that very science. Man knows at last that he is alone in the indifferent immensity of the universe, whence which he has emerged by chance. His duty, like his fate, is written nowhere.

As an exercise of the reasoning faculty, pure mathematics is an admirable exercise, because it consists of reasoning alone, and does not encumber the student with an exercise of judgment: and it is well to begin with learning one thing at a time, and to defer a combination of mental exercises to a later period.

As he sat alone in a garden, he [Isaac Newton in 1666, age 24] fell into a speculation on the power of gravity; that as this power is not found sensibly diminished at the remotest distance from the centre of the earth to which we can rise, neither at the tops of the loftiest buildings, nor even on the summits of the highest mountains, it appeared to him reasonable to conclude that this power must extend much further than was usually thought: why not as high as the moon? said he to himself; and if so, her motion must be influenced by it; perhaps she is retained in her orbit thereby.

As in political revolutions, so in paradigm choice—there is no standard higher than the assent of the relevant community... this issue of paradigm choice can never be unequivocally settled by logic and experiment alone.

As soon as he ceased to be mad he became merely stupid. There are maladies we must not seek to cure because they alone protect us from others that are more serious.

At the bottom of every leaf-stem is a cradle, and in it is an infant germ; the winds will rock it, the birds will sing to it all summer long, but the next season it will unfold and go alone.

But come, hear my words, for truly learning causes the mind to grow. For as I said before in declaring the ends of my words … at one time there grew to be the one alone out of many, and at another time it separated so that there were many out of the one; fire and water and earth and boundless height of air, and baneful Strife apart from these, balancing each of them, and Love among them, their equal in length and breadth.

But concerning vision alone is a separate science formed among philosophers, namely, optics, and not concerning any other sense ... It is possible that some other science may be more useful, but no other science has so much sweetness and beauty of utility. Therefore it is the flower of the whole of philosophy and through it, and not without it, can the other sciences be known.

But in the heavens we discover by their light, and by their light alone, stars so distant from each other that no material thing can ever have passed from one to another; and yet this light, which is to us the sole evidence of the existence of these distant worlds, tells us also that each of them is built up of molecules of the same kinds as those which we find on earth. A molecule of hydrogen, for example, whether in Sirius or in Arcturus, executes its vibrations in precisely the same time. Each molecule, therefore, throughout the universe, bears impressed on it the stamp of a metric system as distinctly as does the metre of the Archives at Paris, or the double royal cubit of the Temple of Karnac ... the exact quantity of each molecule to all others of same kind gives it, as Sir John Herschel has well said, the essential character of a manufactured article and precludes the idea of its being external and self-existent.

By no amount of reasoning can we altogether eliminate all contingency from our world. Moreover, pure speculation alone will not enable us to get a determinate picture of the existing world. We must eliminate some of the conflicting possibilities, and this can be brought about only by experiment and observation.

By teaching us how to cultivate each ferment in its purity—in other words, by teaching us how to rear the individual organism apart from all others,—Pasteur has enabled us to avoid all these errors. And where this isolation of a particular organism has been duly effected it grows and multiplies indefinitely, but no change of it into another organism is ever observed. In Pasteur’s researches the Bacterium remained a Bacterium, the Vibrio a Vibrio, the Penicillium a Penicillium, and the Torula a Torula. Sow any of these in a state of purity in an appropriate liquid; you get it, and it alone, in the subsequent crop. In like manner, sow smallpox in the human body, your crop is smallpox. Sow there scarlatina, and your crop is scarlatina. Sow typhoid virus, your crop is typhoid—cholera, your crop is cholera. The disease bears as constant a relation to its contagium as the microscopic organisms just enumerated do to their germs, or indeed as a thistle does to its seed.

Casting off the dark fog of verbal philosophy and vulgar medicine, which inculcate names alone ... I tried a series of experiments to explain more clearly many phenomena, particularly those of physiology. In order that I might subject as far as possible the reasonings of the Galenists and Peripatetics to sensory criteria, I began, after trying experiments, to write dialogues in which a Galenist adduced the better-known and stronger reasons and arguments; these a mechanist surgeon refuted by citing to the contrary the experiments I had tried, and a third, neutral interlocutor weighed the reasons advanced by both and provided an opportunity for further progress.

Chance alone is at the source of every innovaton, of all creation in the biosphere. Pure chance, only chance, absolute but blind liberty is at the root of the prodigious edifice that is evolution... It today is the sole conceivable hypothesis, the only one that squares with observed and tested fact.
Stating life began by the chance collision of particles of nucleic acid in the “prebiotic soup.”

Chemistry is the science or study of those effects and qualities of matter which are discovered by mixing bodies variously together, or applying them to one another with a view to mixture, and by exposing them to different degrees of heat, alone, or in mixture with one another, in order to enlarge our knowledge of nature, and to promote the useful arts.

Complex organisms cannot be construed as the sum of their genes, nor do genes alone build particular items of anatomy or behavior by them selves. Most genes influence several aspects of anatomy and behavior–as they operate through complex interactions with other genes and their products, and with environmental factors both within and outside the developing organism. We fall into a deep error, not just a harmful oversimplification, when we speak of genes ‘for’ particular items of anatomy or behavior.

Confined to its true domain, mathematical reasoning is admirably adapted to perform the universal office of sound logic: to induce in order to deduce, in order to construct. … It contents itself to furnish, in the most favorable domain, a model of clearness, of precision, and consistency, the close contemplation of which is alone able to prepare the mind to render other conceptions also as perfect as their nature permits. Its general reaction, more negative than positive, must consist, above all, in inspiring us everywhere with an invincible aversion for vagueness, inconsistency, and obscurity, which may always be really avoided in any reasoning whatsoever, if we make sufficient effort.

Considering that, among all those who up to this time made discoveries in the sciences, it was the mathematicians alone who had been able to arrive at demonstrations—that is to say, at proofs certain and evident—I did not doubt that I should begin with the same truths that they have investigated, although I had looked for no other advantage from them than to accustom my mind to nourish itself upon truths and not to be satisfied with false reasons.

Dr Bell fell down the well
And broke his collar bone
Doctors should attend the sick
And leave the well alone.

Each new atom brings something of the personality of its element to the molecule, and this conspiracy of atoms results in a molecule with properties that are richer than those of each atom alone.

Euclid alone has looked on Beauty bare.
Let all who prate of Beauty hold their peace,
And lay them prone upon the earth and cease
To ponder on themselves, the while they stare
At nothing, intricately drawn nowhere
In shapes of shifting lineage; let geese
Gabble and hiss, but heroes seek release
From dusty bondage into luminous air.
O blinding hour, O holy, terrible day,
When first the shaft into his vision shone
Of light anatomized! Euclid alone
Has looked on Beauty bare. Fortunate they
Who, though once only and then but far away,
Have heard her massive sandal set on stone.

Euclid alone
Has looked on Beauty bare.
He turned away at once;
Far too polite to stare.

Even if only one in a hundred of the ten billion suitable planets has actually got life well under way, there would be more than 100 million such planets. No, it is presumptuous to think that we are alone.

Even today a good many distinguished minds seem unable to accept or even to understand that from a source of noise natural selection alone and unaided could have drawn all the music of the biosphere. In effect natural selection operates upon the products of chance and can feed nowhere else; but it operates in a domain of very demanding conditions, and from this domain chance is barred. It is not to chance but to these conditions that eveloution owes its generally progressive cource, its successive conquests, and the impresssion it gives of a smooth and steady unfolding.

Even when all is known, the care of a man is not yet complete, because eating alone will not keep a man well; he must also take exercise. For food and exercise, while possessing opposite qualities, yet work together to produce health.

Every occurrence in Nature is preceded by other occurrences which are its causes, and succeeded by others which are its effects. The human mind is not satisfied with observing and studying any natural occurrence alone, but takes pleasure in connecting every natural fact with what has gone before it, and with what is to come after it.

Every where I see bliss, from which I alone am irrevocably excluded.

Every word carries its own surprises and offers its own rewards to the reflective mind. Their amazing variety is a constant delight. I do not believe that I am alone in this—a fascination with words is shared by people in all countries and all walks of life.

Exits sun; enters moon.
This moon is never alone.
Stars are seen all around.
These twinklers do not make a sound.
The tiny ones shine from their place.
Mother moon watches with a smiling face.
Its light is soothing to the eyes.
Night’s darkness hides its face.
Cool and calm is its light.
Heat and sweat are never felt.
Some days, moon is not seen.
Makes kids wonder, where had it been?
Partial eclipse shades the moon.
In summers it does not arrive soon.
Beautiful is this milky ball.
It is the love of one and all.

Exper. I. I made a small hole in a window-shutter, and covered it with a piece of thick paper, which I perforated with a fine needle. For greater convenience of observation I placed a small looking-glass without the window-shutter, in such a position as to reflect the sun's light, in a direction nearly horizontal, upon the opposite wall, and to cause the cone of diverging light to pass over a table on which were several little screens of card-paper. I brought into the sunbeam a slip of card, about one-thirtieth of an inch in breadth, and observed its shadow, either on the wall or on other cards held at different distances. Besides the fringes of colour on each side of the shadow, the shadow itself was divided by similar parallel fringes, of smaller dimensions, differing in number, according to the distance at which the shadow was observed, but leaving the middle of the shadow always white. Now these fringes were the joint effects of the portions of light passing on each side of the slip of card and inflected, or rather diffracted, into the shadow. For, a little screen being placed a few inches from the card, so as to receive either edge of the shadow on its margin, all the fringes which had before been observed in the shadow on the wall, immediately disappeared, although the light inflected on the other side was allowed to retain its course, and although this light must have undergone any modification that the proximity of the other edge of the slip of card might have been capable of occasioning... Nor was it for want of a sufficient intensity of light that one of the two portions was incapable of producing the fringes alone; for when they were both uninterrupted, the lines appeared, even if the intensity was reduced to one-tenth or one-twentieth.

Experiment is the interpreter of nature. Experiments never deceive. It is our judgment which sometimes deceives itself because it expects results which experiment refuses. We must consult experiment, varying the circumstances, until we have deduced general rules, for experiment alone can furnish reliable rules.

Experiment is the sole source of truth. It alone can teach us something new; it alone can give us certainty.

Facts alone, no matter how numerous or verifiable, do not automatically arrange themselves into an intelligible, or truthful, picture of the world. It is the task of the human mind to invent a theoretical framework to account for them.

Facts, and facts alone, are the foundation of science... When one devotes oneself to experimental research it is in order to augment the sum of known facts, or to discover their mutual relations.

Faith is a permanent and vital endowment of the human mind—a part of reason itself. The insane alone are without it.

Few men live lives of more devoted self-sacrifice than the family physician, but he may become so completely absorbed in work that leisure is unknown…. More than most men he feels the tragedy of isolation—that inner isolation so well expressed in Matthew Arnold’s line “We mortal millions live alone.”

For it is owing to their wonder that men now both begin and at first began to philosophize; they wondered originally at the obvious difficulties, then advanced little by little and stated difficulties about the greater matters, e.g. about the phenomena of the moon and those of the sun and the stars, and about the genesis of the universe. And a man who is puzzled and wonders thinks himself ignorant (whence even the lover of myth is in a sense a lover of wisdom, for myth is composed of wonders); therefore since they philosophized in order to escape from ignorance, evidently they were pursuing science in order to know, and not for any utilitarian end. And this is confirmed by the facts; for it was when almost all the necessities of life and the things that make for comfort and recreation were present, that such knowledge began to be sought. Evidently then we do not seek it for the sake of any advantage; but as the man is free, we say, who exists for himself and not for another, so we pursue this as the only free science, for it alone exists for itself.

For keenest enjoyment, I visit when the dew is on them, or in cloudy weather, or when the rain is falling: and I must be alone or with someone who cares for them as I do.

For other great mathematicians or philosophers, he [Gauss] used the epithets magnus, or clarus, or clarissimus; for Newton alone he kept the prefix summus.

For scholars and laymen alike it is not philosophy but active experience in mathematics itself that can alone answer the question: What is mathematics?

For the Members of the Assembly having before their eyes so many fatal Instances of the errors and falshoods, in which the greatest part of mankind has so long wandred, because they rely'd upon the strength of humane Reason alone, have begun anew to correct all Hypotheses by sense, as Seamen do their dead Reckonings by Cœlestial Observations; and to this purpose it has been their principal indeavour to enlarge and strengthen the Senses by Medicine, and by such outward Instruments as are proper for their particular works.

For, in mathematics or symbolic logic, reason can crank out the answer from the symboled equations—even a calculating machine can often do so—but it cannot alone set up the equations. Imagination resides in the words which define and connect the symbols—subtract them from the most aridly rigorous mathematical treatise and all meaning vanishes. Was it Eddington who said that we once thought if we understood 1 we understood 2, for 1 and 1 are 2, but we have since found we must learn a good deal more about “and”?

From my father I learned to build things, to take them apart, and to fix mechanical and electrical equipment in general. I spent vast hours in a woodworking shop he maintained in the basement of our house, building gadgets, working both with my father and alone, often late into the night. … This play with building, fixing, and designing was my favorite activity throughout my childhood, and was a wonderful preparation for my later career as an experimentalist working on the frontiers of chemistry and physics.

From packaging materials, through fibers, foams and surface coatings, to continuous extrusions and large-scale moldings, plastics have transformed almost every aspect of life. Without them, much of modern medicine would be impossible and the consumer electronics and computer industries would disappear. Plastic sewage and water pipes alone have made an immeasurable contribution to public health worldwide.

From this fountain (the free will of God) it is those laws, which we call the laws of nature, have flowed, in which there appear many traces of the most wise contrivance, but not the least shadow of necessity. These therefore we must not seek from uncertain conjectures, but learn them from observations and experimental. He who is presumptuous enough to think that he can find the true principles of physics and the laws of natural things by the force alone of his own mind, and the internal light of his reason, must either suppose the world exists by necessity, and by the same necessity follows the law proposed; or if the order of Nature was established by the will of God, the [man] himself, a miserable reptile, can tell what was fittest to be done.

Gold-Mines. Gold is not found in quartz alone; its richest lodes are in the eyes and ears of the public, but these are harder to work and to prospect than any quartz vein.

Governments of the Industrial World, you weary giants of flesh and steel, I come from Cyberspace, the new home of Mind. On behalf of the future, I ask you of the past to leave us alone. You are not welcome among us. You have no sovereignty where we gather.

Habit is thus the enormous fly-wheel of society, its most precious conservative agent. It alone is what keeps us all within the bounds of ordinance, and saves the children of fortune from the envious uprisings of the poor. It alone prevents the hardest and most repulsive walks of life from being deserted by those brought up to tread therein.

He [Sylvester] had one remarkable peculiarity. He seldom remembered theorems, propositions, etc., but had always to deduce them when he wished to use them. In this he was the very antithesis of Cayley, who was thoroughly conversant with everything that had been done in every branch of mathematics.
I remember once submitting to Sylvester some investigations that I had been engaged on, and he immediately denied my first statement, saying that such a proposition had never been heard of, let alone proved. To his astonishment, I showed him a paper of his own in which he had proved the proposition; in fact, I believe the object of his paper had been the very proof which was so strange to him.

He that drinks his Cyder alone, let him catch his Horse alone.

He who is only a traveler learns things at second-hand and by the halves, and is poor authority. We are most interested when science reports what those men already know practically or instinctively, for that alone is a true humanity.

His [Faraday’s] third great discovery is the Magnetization of Light, which I should liken to the Weisshorn among mountains—high, beautiful, and alone.

History tells us that [leading minds] can’t do it alone. From landing on the moon, to sequencing the human genome, to inventing the Internet, America has been the first to cross that new frontier because we had leaders who paved the way: leaders like President Kennedy, who inspired us to push the boundaries of the known world and achieve the impossible; leaders who not only invested in our scientists, but who respected the integrity of the scientific process.

How hard to realize that every camp of men or beast has this glorious starry firmament for a roof! In such places standing alone on the mountain-top it is easy to realize that whatever special nests we make - leaves and moss like the marmots and birds, or tents or piled stone - we all dwell in a house of one room - the world with the firmament for its roof - and are sailing the celestial spaces without leaving any track.

How much do I love that noble man / More than I could tell with words / I fear though he’ll remain alone / With a holy halo of his own.

Human consciousness is just about the last surviving mystery. A mystery is a phenomenon that people don’t know how to think about—yet. There have been other great mysteries: the mystery of the origin of the universe, the mystery of life and reproduction, the mystery of the design to be found in nature, the mysteries of time, space, and gravity. These were not just areas of scientific ignorance, but of utter bafflement and wonder. We do not yet have the final answers to any of the questions of cosmology and particle physics, molecular genetics and evolutionary theory, but we do know how to think about them. The mysteries haven't vanished, but they have been tamed. They no longer overwhelm our efforts to think about the phenomena, because now we know how to tell the misbegotten questions from the right questions, and even if we turn out to be dead wrong about some of the currently accepted answers, we know how to go about looking for better answers. With consciousness, however, we are still in a terrible muddle. Consciousness stands alone today as a topic that often leaves even the most sophisticated thinkers tongue-tied and confused. And, as with all the earlier mysteries, there are many who insist—and hope—that there will never be a demystification of consciousness.

I also maintain that clear knowledge of natural science must be acquired, in the first instance, through mastery of medicine alone.

I am convinced that it is impossible to expound the methods of induction in a sound manner, without resting them upon the theory of probability. Perfect knowledge alone can give certainty, and in nature perfect knowledge would be infinite knowledge, which is clearly beyond our capacities. We have, therefore, to content ourselves with partial knowledge—knowledge mingled with ignorance, producing doubt.

I am convinced that this is the only means of advancing science, of clearing the mind from a confused heap of contradictory observations, that do but perplex and puzzle the Student, when he compares them, or misguide him if he gives himself up to their authority; but bringing them under one general head, can alone give rest and satisfaction to an inquisitive mind.

I am further inclined to think, that when our views are sufficiently extended, to enable us to reason with precision concerning the proportions of elementary atoms, we shall find the arithmetical relation alone will not be sufficient to explain their mutual action, and that we shall be obliged to acquire a geometric conception of their relative arrangement in all three dimensions of solid extension.

I am mindful that scientific achievement is rooted in the past, is cultivated to full stature by many contemporaries and flourishes only in favorable environment. No individual is alone responsible for a single stepping stone along the path of progress, and where the path is smooth progress is most rapid. In my own work this has been particularly true.

I began to realize that something had to be done about this. I saw that I was the only Hispanic nurse who was going to Washington to work with the federal government, review research and education grants, etc. There was nobody else. I looked behind me and thought: “Where are my people?”

I believe that the science of chemistry alone almost proves the existence of an intelligent creator.

I do not think words alone will solve humanity’s present problems. The sound of bombs drowns out men’s voices. In times of peace I have great faith in the communication of ideas among thinking men, but today, with brute force dominating so many millions of lives, I fear that the appeal to man’s intellect is fast becoming virtually meaningless.

I find in Geology a never failing interest, as [it] has been remarked, it creates the same gran[d] ideas respecting this world, which Astronomy do[es] for the universe.—We have seen much fine scenery that of the Tropics in its glory & luxuriance, exceeds even the language of Humboldt to describe. A Persian writer could alone do justice to it, & if he succeeded he would in England, be called the 'grandfather of all liars'.— But I have seen nothing, which more completely astonished me, than the first sight of a Savage; It was a naked Fuegian his long hair blowing about, his face besmeared with paint. There is in their countenances, an expression, which I believe to those who have not seen it, must be inconceivably wild. Standing on a rock he uttered tones & made gesticulations than which, the cries of domestic animals are far more intelligible.

I have always liked horticulturists, people who make their living from orchards and gardens, whose hands are familiar with the feel of the bark, whose eyes are trained to distinguish the different varieties, who have a form memory. Their brains are not forever dealing with vague abstractions; they are satisfied with the romance which the seasons bring with them, and have the patience and fortitude to gamble their lives and fortunes in an industry which requires infinite patience, which raise hopes each spring and too often dashes them to pieces in fall. They are always conscious of sun and wind and rain; must always be alert lest they lose the chance of ploughing at the right moment, pruning at the right time, circumventing the attacks of insects and fungus diseases by quick decision and prompt action. They are manufacturers of a high order, whose business requires not only intelligence of a practical character, but necessitates an instinct for industry which is different from that required by the city dweller always within sight of other people and the sound of their voices. The successful horticulturist spends much time alone among his trees, away from the constant chatter of human beings.

I have ever been prone to seek adventure and to investigate and experiment where wiser men would have left well enough alone.

I have said that mathematics is the oldest of the sciences; a glance at its more recent history will show that it has the energy of perpetual youth. The output of contributions to the advance of the science during the last century and more has been so enormous that it is difficult to say whether pride in the greatness of achievement in this subject, or despair at his inability to cope with the multiplicity of its detailed developments, should be the dominant feeling of the mathematician. Few people outside of the small circle of mathematical specialists have any idea of the vast growth of mathematical literature. The Royal Society Catalogue contains a list of nearly thirty- nine thousand papers on subjects of Pure Mathematics alone, which have appeared in seven hundred serials during the nineteenth century. This represents only a portion of the total output, the very large number of treatises, dissertations, and monographs published during the century being omitted.

I know nothing of the science of astrology and I consider it to be a science, if it is a science, of doubtful value, to be severely left alone by those who have any faith in Providence.

I prefer the spagyric chemical physicians, for they do not consort with loafers or go about gorgeous in satins, silks and velvets, gold rings on their fingers, silver daggers hanging at their sides and white gloves on their hands, but they tend their work at the fire patiently day and night. They do not go promenading, but seek their recreation in the laboratory, wear plain learthern dress and aprons of hide upon which to wipe their hands, thrust their fingers amongst the coals, into dirt and rubbish and not into golden rings. They are sooty and dirty like the smiths and charcoal burners, and hence make little show, make not many words and gossip with their patients, do not highly praise their own remedies, for they well know that the work must praise the master, not the master praise his work. They well know that words and chatter do not help the sick nor cure them... Therefore they let such things alone and busy themselves with working with their fires and learning the steps of alchemy. These are distillation, solution, putrefaction, extraction, calcination, reverberation, sublimination, fixation, separation, reduction, coagulation, tinction, etc.

I remember discussions with Bohr which went through many hours till very late at night and ended almost in despair; and when at the end of the discussion I went alone for a walk in the neighboring park I repeated to myself again and again the question: Can nature possibly be as absurd as it seemed to us in these atomic experiments?

I think it would be a very rash presumption to think that nowhere else in the cosmos has nature repeated the strange experiment which she has performed on earth—that the whole purpose of creation has been staked on this one planet alone. It is probable that dotted through the cosmos there are other suns which provide the energy for life to attendant planets. It is apparent, however, that planets with just the right conditions of temperature, oxygen, water and atmosphere necessary for life are found rarely.
But uncommon as a habitable planet may be, non-terrestrial life exists, has existed and will continue to exist. In the absence of information, we can only surmise that the chance that it surpasses our own is as good as that it falls below our level.

I was then in Germany, where I had been drafted because of the wars that are still going on there, and as I was returning to the army from the emperor's coronation, the arrival of winter delayed me in quarters where, finding no company to distract me and, luckily, having no cares or passions to trouble me, I used to spend the whole day alone in a room, that was heated by a stove, where I had plenty of time to concentrate on my own thoughts.

If a man would be alone, let him look at the stars. … One might think the atmosphere was made transparent with this design, to give man, in the heavenly bodies, the perpetual presence of the sublime.

If any one should ask me what I consider the most distinctive, progressive feature of California, I should answer promptly, its cable-car system. And it is not alone its system which seems to have reached a point of perfection, but the amazing length of the ride that is given you for the chink of a nickel. I have circled this city of San Francisco, … for this smallest of Southern coins.

If everything in chemistry is explained in a satisfactory manner without the help of phlogiston, it is by that reason alone infinitely probable that the principle does not exist; that it is a hypothetical body, a gratuitous supposition; indeed, it is in the principles of good logic, not to multiply bodies without necessity.

If in the citation of work that we have both done together only one of us is named, and especially in a journal [Annalen der Chemie] in which both are named on the title page, about which everyone knows that you are the actual editor, and this editor allows that to happen and does not show the slightest consideration to report it, then everyone will conclude that this represents an agreement between us, that the work is yours alone, and that I am a jackass.

If it’s true that our species is alone in the universe, then I’d have to say that the universe aimed rather low and settled for very little.

If more of our resources were invested in preventing sickness and accidents, fewer would have to be spent on costly cures. … In short, we should build a true “health” system—and not a “sickness” system alone.

If only the Geologists would let me alone, I could do very well, but those dreadful Hammers! I hear the clink of them at the end of every cadence of the Bible verses.

If two or more instances of the phenomenon under investigation have only one circumstance in common, the circumstance in which alone all the instances agree is the cause (or effect) of the given phenomenon.

If we had a thorough knowledge of all the parts of the seed of any animal (e.g., man), we could from that alone, by reasons entirely mathematical and certain, deduce the whole conformation and figure of each of its members, and, conversely, if we knew several peculiarities of this conformation, we would from those deduce the nature of its seed.

If we take science as our sole guide, if we accept and hold fast that alone which is verifiable, the old theology must go.

If words are not things, or maps are not the actual territory, then, obviously, the only possible link between the objective world and the linguistic world is found in structure, and structure alone.

If you defend a behavior by arguing that people are programmed directly for it, then how do you continue to defend it if your speculation is wrong, for the behavior then becomes unnatural and worthy of condemnation. Better to stick resolutely to a philosophical position on human liberty: what free adults do with each other in their own private lives is their business alone. It need not be vindicated–and must not be condemned–by genetic speculation.

If, unwarned by my example, any man shall undertake and shall succeed in really constructing an engine embodying in itself the whole of the executive department of mathematical analysis upon different principles or by simpler mechanical means, I have no fear of leaving my reputation in his charge, for he alone will be fully able to appreciate the nature of my efforts and the value of their results.

Imperceptibly a change had been wrought in me until I no longer felt alone in a strange, silent country. I had learned to hear the echoes of a time when every living thing upon this land and even the varied overshadowing skies had its voice, a voice that was attentively heard and devoutly heeded by the ancient people of America. Henceforth, to me the plants, the trees, the clouds and all things had become vocal with human hopes, fears and supplications.

In all cases when a particular agent or cause is to be studied, experiments should be arranged in such a way as to lead if possible to results depending on it alone ; or, if this cannot be done, they should be arranged so as to increase the effects due to the cause to be studied till these so far exceed the unavoidable concomitants, that the latter may be considered as only disturbing, not essentially modifying the effects of the principal agent.

In all works on Natural History, we constantly find details of the marvellous adaptation of animals to their food, their habits, and the localities in which they are found. But naturalists are now beginning to look beyond this, and to see that there must be some other principle regulating the infinitely varied forms of animal life. It must strike every one, that the numbers of birds and insects of different groups having scarcely any resemblance to each other, which yet feed on the same food and inhabit the same localities, cannot have been so differently constructed and adorned for that purpose alone. Thus the goat-suckers, the swallows, the tyrant fly-catchers, and the jacamars, all use the same kind ‘Of food, and procure it in the same manner: they all capture insects on the wing, yet how entirely different is the structure and the whole appearance of these birds!

In geometry, as in most sciences, it is very rare that an isolated proposition is of immediate utility. But the theories most powerful in practice are formed of propositions which curiosity alone brought to light, and which long remained useless without its being able to divine in what way they should one day cease to be so. In this sense it may be said, that in real science, no theory, no research, is in effect useless.

In many cases, mathematics is an escape from reality. The mathematician finds his own monastic niche and happiness in pursuits that are disconnected from external affairs. Some practice it as if using a drug. Chess sometimes plays a similar role. In their unhappiness over the events of this world, some immerse themselves in a kind of self-sufficiency in mathematics. (Some have engaged in it for this reason alone.)

In most sciences one generation tears down what another has built, and what one has established, another undoes. In mathematics alone each generation adds a new storey to the old structure.