Abroad, energy efficiency was a respectable form of engineering. Whereas Americans largely purchased by least “first cost,” Europeans understood and operated under the concept of “life cycle cost.”

Although we may be at a loss to explain the nature of that substance in the nerves, by whose intervention the mind seems enabled to act upon the muscles; and though we may be unacquainted with the intimate structure of those fibres upon which this substance operates, yet we have no room to doubt that voluntary motion is produced by the immediate energy of the mind; manifold experience convincing us, that though there be required certain conditions in the body in order to its performance, it is nevertheless owing to the will.

Complex organisms cannot be construed as the sum of their genes, nor do genes alone build particular items of anatomy or behavior by them selves. Most genes influence several aspects of anatomy and behavior–as they operate through complex interactions with other genes and their products, and with environmental factors both within and outside the developing organism. We fall into a deep error, not just a harmful oversimplification, when we speak of genes ‘for’ particular items of anatomy or behavior.

Euclidean mathematics assumes the completeness and invariability of mathematical forms; these forms it describes with appropriate accuracy and enumerates their inherent and related properties with perfect clearness, order, and completeness, that is, Euclidean mathematics operates on forms after the manner that anatomy operates on the dead body and its members. On the other hand, the mathematics of variable magnitudes—function theory or analysis—considers mathematical forms in their genesis. By writing the equation of the parabola, we express its law of generation, the law according to which the variable point moves. The path, produced before the eyes of the student by a point moving in accordance to this law, is the parabola.
If, then, Euclidean mathematics treats space and number forms after the manner in which anatomy treats the dead body, modern mathematics deals, as it were, with the living body, with growing and changing forms, and thus furnishes an insight, not only into nature as she is and appears, but also into nature as she generates and creates,—reveals her transition steps and in so doing creates a mind for and understanding of the laws of becoming. Thus modern mathematics bears the same relation to Euclidean mathematics that physiology or biology … bears to anatomy.

Every form of life can be produced by physical forces in one of two ways: either by coming into being out of formless matter, or by the modification of an already existing form by a continued process of shaping. In the latter case the cause of this modification may lie either in the influence of a dissimilar male generative matter upon the female germ, or in the influence of other powers which operate only after procreation.

Here I am at the limit which God and nature has assigned to my individuality. I am compelled to depend upon word, language and image in the most precise sense, and am wholly unable to operate in any manner whatever with symbols and numbers which are easily intelligible to the most highly gifted minds.

I became expert at dissecting crayfish. At one point I had a crayfish claw mounted on an apparatus in such a way that I could operate the individual nerves. I could get the several-jointed claw to reach down and pick up a pencil and wave it around. I am not sure that what I was doing had much scientific value, although I did learn which nerve fiber had to be excited to inhibit the effects of another fiber so that the claw would open. And it did get me interested in robotic instrumentation, something that I have now returned to. I am trying to build better micromanipulators for surgery and the like.

It is impossible to imagine the universe run by a wise, just and omnipotent God, but it is quite easy to imagine it run by a board of gods. If such a board actually exists it operates precisely like the board of a corporation that is losing money.

It is the intact and functioning organism on which natural selection operates. Organisms are therefore the central element of concern to the biologist who aspires to a broad and integrated understanding of biology.

It’s impossible to move, to live, to operate at any level without leaving traces, bits, seemingly meaningless fragments of personal information.

Learning how to operate a soul figures to take time.

Microsoft isn’t evil, they just make really crappy operating systems.

No! What we need are not prohibitory marriage laws, but a reformed society, an educated public opinion which will teach individual duty in these matters. And it is to the women of the future that I look for the needed reformation. Educate and train women so that they are rendered independent of marriage as a means of gaining a home and a living, and you will bring about natural selection in marriage, which will operate most beneficially upon humanity. When all women are placed in a position that they are independent of marriage, I am inclined to think that large numbers will elect to remain unmarried—in some cases, for life, in others, until they encounter the man of their ideal. I want to see women the selective agents in marriage; as things are, they have practically little choice. The only basis for marriage should be a disinterested love. I believe that the unfit will be gradually eliminated from the race, and human progress secured, by giving to the pure instincts of women the selective power in marriage. You can never have that so long as women are driven to marry for a livelihood.

Quantity is that which is operated with according to fixed mutually consistent laws. Both operator and operand must derive their meaning from the laws of operation. In the case of ordinary algebra these are the three laws already indicated [the commutative, associative, and distributive laws], in the algebra of quaternions the same save the law of commutation for multiplication and division, and so on. It may be questioned whether this definition is sufficient, and it may be objected that it is vague; but the reader will do well to reflect that any definition must include the linear algebras of Peirce, the algebra of logic, and others that may be easily imagined, although they have not yet been developed. This general definition of quantity enables us to see how operators may be treated as quantities, and thus to understand the rationale of the so called symbolical methods.

The ideas that are basic to [my work] often bear witness to my amazement and wonder at the laws of nature which operate in the world around us.

The sick in soul insist that it is humanity that is sick, and they are the surgeons to operate on it. They want to turn the world into a sickroom. And once they get humanity strapped to the operating table, they operate on it with an ax.

The surgeon is a man of action. By temperament and by training he prefers to serve the sick by operating on them, and he inwardly commiserates with a patient so unfortunate as to have a disease not suited to surgical treatment. Young surgeons, busy mastering the technicalities of the art, are particularly alert to seize every legitimate opportunity to practice technical maneuvers, the more complicated the better.

The telegraph is a kind of very long cat. You pull his tail in New York and he is mewing in Los Angeles. Radio operates in exactly the same way, except there is no cat.

You see, wire telegraph is a kind of a very, very long cat. You pull his tail in New York and his head is meowing in Los Angeles. Do you understand this? And radio operates exactly the same way: you send signals here, they receive them there. The only difference is that there is no cat.
When asked to describe radio