... [I]nfectious disease is merely a disagreeable instance of a widely prevalent tendency of all living creatures to save themselves the bother of building, by their own efforts, the things they require. Whenever they find it possible to take advantage of the constructive labors of others, this is the path of least resistance. The plant does the work with its roots and its green leaves. The cow eats the plant. Man eats both of them; and bacteria (or investment bankers) eat the man. ...

… for it is very probable, that the motion of gravity worketh weakly, both far from the earth, and also within the earth: the former because the appetite of union of dense bodies with the earth, in respect of the distance, is more dull: the latter, because the body hath in part attained its nature when it is some depth in the earth.
[Foreshadowing Newton's Universal Law of Gravitation (1687)]

… however useful the words may have been in the past, they have now become handicaps to the further development of knowledge. Words like botany and zoology imply that plants and animals are quite different things. … But the differences rapidly become blurred when we start looking at the world through a microscope. … The similarities between plants and animals became more important than their differences with the discoveries that both were built up of cells, had sexual reproduction,… nutrition and respiration … and with the development of evolutionary theory.

… the embryological record, as it is usually presented to us, is both imperfect and misleading. It may be compared to an ancient manuscript, with many of the sheets lost, others displaced, and with spurious passages interpolated by a later hand. … Like the scholar with his manuscript, the embryologist has by a process of careful and critical examination to determine where the gaps are present, to detect the later insertions, and to place in order what has been misplaced.

... there is an external world which can in principle be exhaustively described in scientific language. The scientist, as both observer and language-user, can capture the external facts of the world in prepositions that are true if they correspond to the facts and false if they do not. Science is ideally a linguistic system in which true propositions are in one-to-one relation to facts, including facts that are not directly observed because they involve hidden entities or properties, or past events or far distant events. These hidden events are described in theories, and theories can be inferred from observation, that is the hidden explanatory mechnism of the world can be discovered from what is open to observation. Man as scientist is regarded as standing apart from the world and able to experiment and theorize about it objectively and dispassionately.

...[T]he natural history of the rat is tragically similar to that of man ... some of the more obvious qualities in which rats resemble men — ferocity, omnivorousness, and adaptability to all climates ... the irresponsible fecundity with which both species breed at all seasons of the year with a heedlessness of consequences, which subjects them to wholesale disaster on the inevitable, occasional failure of the food supply.... [G]radually, these two have spread across the earth, keeping pace with each other and unable to destroy each other, though continually hostile. They have wandered from East to West, driven by their physical needs, and — unlike any other species of living things — have made war upon their own kind. The gradual, relentless, progressive extermination of the black rat by the brown has no parallel in nature so close as that of the similar extermination of one race of man by another...

...after my first feeling of revulsion had passed, I spent three of the most entertaining and instructive weeks of my life studying the fascinating molds which appeared one by one on the slowly disintegrating mass of horse-dung. Microscopic molds are both very beautiful and absorbingly interesting. The rapid growth of their spores, the way they live on each other, the manner in which the different forms come and go, is so amazing and varied that I believe a man could spend his life and not exhaust the forms or problems contained in one plate of manure.

[1665-06-10] ...In the evening home to supper, and there to my great trouble hear that the plague is come into the City (though it hath these three or four weeks since its beginning been wholly out of the City); but where it begin but in my good friend and neighbour's, Dr Burnett in Fanchurch Street - which in both points troubles me mightily. To the office to finish my letters, and then home to bed, being troubled at the sickness ... and particularly how to put my things and estate in order, in case it should please God to call me away.

[1665-09-14] ...my finding that although the Bill [total of dead] in general is abated, yet the City within the walls is encreasd and likely to continue so (and is close to our house there) - my meeting dead corps's of the plague, carried to be buried close to me at noonday through the City in Fanchurch-street - to see a person sick of the sores carried close by me by Grace-church in a hackney-coach - my finding the Angell tavern at the lower end of Tower-hill shut up; and more then that, the alehouse at the Tower-stairs; and more then that, that the person was then dying of the plague when I was last there, a little while ago at night, to write a short letter there, and I overheard the mistress of the house sadly saying to her husband somebody was very ill, but did not think it was of the plague - to hear that poor Payne my waterman hath buried a child and is dying himself - to hear that a labourer I sent but the other day to Dagenhams to know how they did there is dead of the plague and that one of my own watermen, that carried me daily, fell sick as soon as he had landed me on Friday morning last, when I had been all night upon the water ... is now dead of the plague - to hear ... that Mr Sidny Mountagu is sick of a desperate fever at my Lady Carteret's at Scott's hall - to hear that Mr. Lewes hath another daughter sick - and lastly, that both my servants, W Hewers and Tom Edwards, have lost their fathers, both in St. Sepulcher's parish, of the plague this week - doth put me into great apprehensions of melancholy, and with good reason. But I put off the thoughts of sadness as much as I can, and the rather to keep my wife in good heart and family also.

[Davy's] March of Glory, which he has run for the last six weeks—within which time by the aid and application of his own great discovery, of the identity of electricity and chemical attractions, he has placed all the elements and all their inanimate combinations in the power of man; having decomposed both the Alkalies, and three of the Earths, discovered as the base of the Alkalies a new metal... Davy supposes there is only one power in the world of the senses; which in particles acts as chemical attractions, in specific masses as electricity, & on matter in general, as planetary Gravitation... when this has been proved, it will then only remain to resolve this into some Law of vital Intellect—and all human knowledge will be Science and Metaphysics the only Science.
In November 1807 Davy gave his famous Second Bakerian Lecture at the Royal Society, in which he used Voltaic batteries to “decompose, isolate and name” several new chemical elements, notably sodium and potassium.

[Defining Life] The definite combination of heterogeneous changes, both simultaneous and successive, in correspondence with external co-existences and sequences.

[Eratosthenes] ... is a mathematician among geographers, and yet a geographer among mathematicians; and consequently on both sides he offers his opponents occasions for contradiction.

[In 1909,] Paris was the center of the aviation world. Aeronautics was neither an industry nor even a science; both were yet to come. It was an “art” and I might say a “passion”. Indeed, at that time it was a miracle. It meant the realization of legends and dreams that had existed for thousands of years and had been pronounced again and again as impossible by scientific authorities. Therefore, even the brief and unsteady flights of that period were deeply impressive. Many times I observed expressions of joy and tears in the eyes of witnesses who for the first time watched a flying machine carrying a man in the air.

[Science moves] with the spirit of an adventure characterized both by youthful arrogance and by the belief that the truth, once found, would be simple as well as pretty.

[The new term] Physicist is both to my mouth and ears so awkward that I think I shall never use it. The equivalent of three separate sounds of i in one word is too much.

[The] seminary spirit of minerals hath its proper wombs where it resides, and is like a Prince or Emperour, whose prescripts both Elements and matter must obey; and it is never idle, but always in action, producing and maintaining natural substances, untill they have fulfilled their destiny.

[To] explain the phenomena of the mineral kingdom ... systems are usually reduced to two classes, according as they refer to the origin of terrestrial bodies to FIRE or to WATER; and ... their followers have of late been distinguished by the fanciful names of Vulcanists and Neptunists. To the former of these Dr HUTTON belongs much more than to the latter; though, as he employs the agency both of fire and water in his system, he cannot, in strict propriety, be arranged with either.

[We need not think] that there is any Contradiction, when Philosophy teaches that to be done by Nature; which Religion, and the Sacred Scriptures, teach us to be done by God: no more, than to say, That the balance of a Watch is moved by the next Wheel, is to deny that Wheel, and the rest, to be moved by the Spring; and that both the Spring, and all the other Parts, are caused to move together by the Maker of them. So God may be truly the Cause of This Effect, although a Thousand other Causes should be supposed to intervene: For all Nature is as one Great Engine, made by, and held in His Hand.

[About John Evershed] There is much in our medallist’s career which is a reminder of the scientific life of Sir William Huggins. They come from the same English neighbourhood and began as amateurs of the best kind. They both possess the same kind of scientific aptitude.

[Students or readers about teachers or authors.] They will listen with both ears to what is said by the men just a step or two ahead of them, who stand nearest to them, and within arm’s reach. A guide ceases to be of any use when he strides so far ahead as to be hidden by the curvature of the earth.

Ac kynde wit cometh
Of alle kynnes syghtes,
Of briddes and of beestes,
Of tastes of truthe and of deceites.
Mother-Wit comes from all kinds of experiences,
Of birds and beasts and of tests both true and false.

Dass die bis jetzt unzerlegten chemischen Elemente absolut unzerlegbare Stoffe seien, ist gegenwärtig mindestens sehr unwahrscheinlich. Vielmehr scheint es, dass die Atome der Elemente nicht die letzten, sondern nur die näheren Bestandtheile der Molekeln sowohl der Elemente wie der Verbindungen bilden, die Molekeln oder Molecule als Massentheile erster, die Atome als solche zweiter Ordnung anzusehen sind, die ihrerseits wiederum aus Massentheilchen einer dritten höheren Ordnung bestehen werden.
That the as yet undivided chemical elements are absolutely irreducible substances, is currently at least very unlikely. Rather it seems, that the atoms of elements are not the final, but only the immediate constituents of the molecules of both the elements and the compounds—the Molekeln or molecule as foremost division of matter, the atoms being considered as second order, in turn consisting of matter particles of a third higher order.
[Speculating in 1870, on the existence of subatomic particles, in opening remark of the paper by which he became established as co-discoverer of the Periodic Law.]

Ron Hutcheson, a Knight-Ridder reporter: [Mr. President, what are your] personal views [about the theory of] intelligent design?
President George W. Bush: [Laughing. You're] doing a fine job of dragging me back to the past [days as governor of Texas]. ... Then, I said that, first of all, that decision should be made to local school districts, but I felt like both sides ought to be properly taught...”
Hutcheson: Both sides ought to be properly taught?
President: Yes ... so people can understand what the debate is about.
Hutcheson: So the answer accepts the validity of “intelligent design” as an alternative to evolution?
President: I think that part of education is to expose people to different schools of thought, and I'm not suggesting—you're asking me whether or not people ought to be exposed to different ideas, and the answer is yes.
Hutcheson: So we've got to give these groups—...
President: [interrupting] Very interesting question, Hutch. [Laughter from other reporters]

Where faith commences, science ends. Both these arts of the human mind must be strictly kept apart from each other. Faith has its origin in the poetic imagination; knowledge, on the other hand, originates in the reasoning intelligence of man. Science has to pluck the blessed fruits from the tree of knowledge, unconcerned whether these conquests trench upon the poetical imaginings of faith or not.

A … difference between most system-building in the social sciences and systems of thought and classification of the natural sciences is to be seen in their evolution. In the natural sciences both theories and descriptive systems grow by adaptation to the increasing knowledge and experience of the scientists. In the social sciences, systems often issue fully formed from the mind of one man. Then they may be much discussed if they attract attention, but progressive adaptive modification as a result of the concerted efforts of great numbers of men is rare.

A book should have either intelligibility or correctness; to combine the two is impossible, but to lack both is to be unworthy of a place as Euclid has occupied in education.

A century ago, Darwin and his friends were thought to be dangerous atheists, but their heresy simply replaced a benevolent personal deity called God by a benevolent impersonal deity called Evolution. In their different ways Bishop Wilberforce and T.H. Huxley both believed in Fate.

A crystal is like a class of children arranged for drill, but standing at ease, so that while the class as a whole has regularity both in time and space, each individual child is a little fidgety!

A demonstrative and convincing proof that an acid does consist of pointed parts is, that not only all acid salts do Crystallize into edges, but all Dissolutions of different things, caused by acid liquors, do assume this figure in their Crystallization; these Crystalls consist of points differing both in length and bigness from one another, and this diversity must be attributed to the keener or blunter edges of the different sorts of acids

A discovery must be, by definition, at variance with existing knowledge. During my lifetime, I made two. Both were rejected offhand by the popes of the field. Had I predicted these discoveries in my applications, and had those authorities been my judges, it is evident what their decisions would have been.

A huge net is being dragged across the sea floor, destroying everything in its path. Ahead of it bloom undersea forests and their hundreds and thousands of living creatures, both plant and animal; behind it is a desert. The net is pulled to the surface and most of the dead and dying life forms in it are thrown out. A few marketable species are retained. [Trawling] is like taking a front-end loader and scraping up your entire front garden and shredding it, keeping a few pebbles, and dumping the rest of it down the drain.

A man cannot be professor of zoölogy on one day and of chemistry on the next, and do good work in both. As in a concert all are musicians,—one plays one instrument, and one another, but none all in perfection.

A moment’s consideration of this case shows what a really great advance in the theory and practise of breeding has been obtained through the discovery of Mendel’s law. What a puzzle this case would have presented to the biologist ten years ago! Agouti crossed with chocolate gives in the second filial generation (not in the first) four varieties, viz., agouti, chocolate, black and cinnamon. We could only have shaken our heads and looked wise (or skeptical).
Then we had no explanation to offer for such occurrences other than the “instability of color characters under domestication,” the “effects of inbreeding,” “maternal impressions.” Serious consideration would have been given to the proximity of cages containing both black and cinnamon-agouti mice.
Now we have a simple, rational explanation, which anyone can put to the test. We are able to predict the production of new varieties, and to produce them.
We must not, of course, in our exuberance, conclude that the powers of the hybridizer know no limits. The result under consideration consists, after all, only in the making of new combinations of unit characters, but it is much to know that these units exist and that all conceivable combinations of them are ordinarily capable of production. This valuable knowledge we owe to the discoverer and to the rediscoverers of Mendel’s law.

A most vile face! and yet she spends me forty pound a year in Mercury and Hogs Bones. All her teeth were made in the Black-Fryars, both her Eyebrows i’ the Strand, and her Hair in Silver-street. Every part of Town owns a Piece of her.

A page from a journal of modern experimental physics will be as mysterious to the uninitiated as a Tibetan mandala. Both are records of enquiries into the nature of the universe.

A reasonable content for general education today, then, seems to me to be as follows: First, a command of the principal linguistic tools essential to the pursuit of either science or art. Second, a familiarity with the scientific method and with its principal applications to both physical and social problems. And third, appreciation and practice of the arts, including literature. Furthermore, these three fields should be so integrated toward a common purpose that the question of their relative importance would not even arise. One does not ask which is the most important leg of a tripod.

A statistician is one who has learned how to get valid evidence from statistics and how (usually) to avoid being misled by irrelevant facts. It’s too bad that we apply the same name to this kind of person that we use for those who only tabulate. It’s as if we had the same name for barbers and brain surgeons because they both work on the head.

A thorough advocate in a just cause, a penetrating mathematician facing the starry heavens, both alike bear the semblance of divinity

A very sincere and serious freshman student came to my office with a question that had clearly been troubling him deeply. He said to me, ‘I am a devout Christian and have never had any reason to doubt evolution, an idea that seems both exciting and well documented. But my roommate, a proselytizing evangelical, has been insisting with enormous vigor that I cannot be both a real Christian and an evolutionist. So tell me, can a person believe both in God and in evolution?’ Again, I gulped hard, did my intellectual duty, a nd reassured him that evolution was both true and entirely compatible with Christian belief –a position that I hold sincerely, but still an odd situation for a Jewish agnostic.

A weird happening has occurred in the case of a lansquenet named Daniel Burghammer, of the squadron of Captain Burkhard Laymann Zu Liebenau, of the honorable Madrucci Regiment in Piadena, in Italy. When the same was on the point of going to bed one night he complained to his wife, to whom he had been married by the Church seven years ago, that he had great pains in his belly and felt something stirring therein. An hour thereafter he gave birth to a child, a girl. When his wife was made aware of this, she notified the occurrence at once. Thereupon he was examined and questioned. … He confessed on the spot that he was half man and half woman and that for more than seven years he had served as a soldier in Hungary and the Netherlands… . When he was born he was christened as a boy and given in baptism the name of Daniel… . He also stated that while in the Netherlands he only slept once with a Spaniard, and he became pregnant therefrom. This, however, he kept a secret unto himself and also from his wife, with whom he had for seven years lived in wedlock, but he had never been able to get her with child… . The aforesaid soldier is able to suckle the child with his right breast only and not at all on the left side, where he is a man. He has also the natural organs of a man for passing water. Both are well, the child is beautiful, and many towns have already wished to adopt it, which, however, has not as yet been arranged. All this has been set down and described by notaries. It is considered in Italy to be a great miracle, and is to be recorded in the chronicles. The couple, however, are to be divorced by the clergy.

About ten months ago [1609] a report reached my ears that a certain Fleming [Hans Lippershey] had constructed a spyglass, by means of which visible objects, though very distant from the eye of the observer, were distinctly seen as if nearby... Of this truly remarkable effect several experiences were related, to which some persons gave credence while others denied them. A few days later the report was confirmed to me in a letter from a noble Frenchman at Paris, Jacques Badovere, which caused me to apply myself wholeheartedly to enquire into the means by which I might arrive at the invention of a similar instrument. This I did shortly afterwards, my basis being the theory of refraction. First I prepared a tube of lead, at the ends of which I fitted two glass lenses, both plane on one side while on the other side one was spherically convex and the other concave.

Adam is fading out. It is on account of Darwin and that crowd. I can see that he is not going to last much longer. There's a plenty of signs. He is getting belittled to a germ—a little bit of a speck that you can't see without a microscope powerful enough to raise a gnat to the size of a church. They take that speck and breed from it: first a flea; then a fly, then a bug, then cross these and get a fish, then a raft of fishes, all kinds, then cross the whole lot and get a reptile, then work up the reptiles till you've got a supply of lizards and spiders and toads and alligators and Congressmen and so on, then cross the entire lot again and get a plant of amphibiums, which are half-breeds and do business both wet and dry, such as turtles and frogs and ornithorhyncuses and so on, and cross-up again and get a mongrel bird, sired by a snake and dam'd by a bat, resulting in a pterodactyl, then they develop him, and water his stock till they've got the air filled with a million things that wear feathers, then they cross-up all the accumulated animal life to date and fetch out a mammal, and start-in diluting again till there's cows and tigers and rats and elephants and monkeys and everything you want down to the Missing Link, and out of him and a mermaid they propagate Man, and there you are! Everything ship-shape and finished-up, and nothing to do but lay low and wait and see if it was worth the time and expense.

Adrenalin does not excite sympathetic ganglia when applied to them directly, as does nicotine. Its effective action is localised at the periphery. The existence upon plain muscle of a peripheral nervous network, that degenerates only after section of both the constrictor and inhibitory nerves entering it, and not after section of either alone, has been described. I find that even after such complete denervation, whether of three days' or ten months' duration, the plain muscle of the dilatator pupillae will respond to adrenalin, and that with greater rapidity and longer persistence than does the iris whose nervous relations are uninjured. Therefore it cannot be that adrenalin excites any structure derived from, and dependent for its persistence on, the peripheral neurone. But since adrenalin does not evoke any reaction from muscle that has at no time of its life been innervated by the sympathetic, the point at which the stimulus of the chemical excitant is received, and transformed into what may cause the change of tension of the muscle fibre, is perhaps a mechanism developed out of the muscle cell in response to its union with the synapsing sympathetic fibre, the function of which is to receive and transform the nervous impulse. Adrenalin might then be the chemical stimulant liberated on each occasion when the impulse arrives at the periphery.

All fossil anthropoids found hitherto have been known only from mandibular or maxillary fragments, so far as crania are concerned, and so the general appearance of the types they represented had been unknown; consequently, a condition of affairs where virtually the whole face and lower jaw, replete with teeth, together with the major portion of the brain pattern, have been preserved, constitutes a specimen of unusual value in fossil anthropoid discovery. Here, as in Homo rhodesiensis, Southern Africa has provided documents of higher primate evolution that are amongst the most complete extant. Apart from this evidential completeness, the specimen is of importance because it exhibits an extinct race of apes intermediate between living anthropoids and man ... Whether our present fossil is to be correlated with the discoveries made in India is not yet apparent; that question can only be solved by a careful comparison of the permanent molar teeth from both localities. It is obvious, meanwhile, that it represents a fossil group distinctly advanced beyond living anthropoids in those two dominantly human characters of facial and dental recession on one hand, and improved quality of the brain on the other. Unlike Pithecanthropus, it does not represent an ape-like man, a caricature of precocious hominid failure, but a creature well advanced beyond modern anthropoids in just those characters, facial and cerebral, which are to be anticipated in an extinct link between man and his simian ancestor. At the same time, it is equally evident that a creature with anthropoid brain capacity and lacking the distinctive, localised temporal expansions which appear to be concomitant with and necessary to articulate man, is no true man. It is therefore logically regarded as a man-like ape. I propose tentatively, then, that a new family of Homo-simidæ be created for the reception of the group of individuals which it represents, and that the first known species of the group be designated Australopithecus africanus, in commemoration, first, of the extreme southern and unexpected horizon of its discovery, and secondly, of the continent in which so many new and important discoveries connected with the early history of man have recently been made, thus vindicating the Darwinian claim that Africa would prove to be the cradle of mankind.

All of my knowledge, of both science and religion, I incorporate into the classical tradition of my painting.

All scientists must focus closely on limited targets. Whether or not one’s findings on a limited subject will have wide applicability depends to some extent on chance, but biologists of superior ability repeatedly focus on questions the answers to which either have wide ramifications or lead to new areas of investigation. One procedure that can be effective is to attempt both reduction and synthesis; that is, direct a question at a phenomenon on one integrative level, identify its mechanism at a simpler level, then extrapolate its consequences to a more complex level of integration.

All that Anatomie can doe is only to shew us the gross and sensible parts of the body, or the vapid and dead juices all which, after the most diligent search, will be noe more able to direct a physician how to cure a disease than how to make a man; for to remedy the defects of a part whose organicall constitution and that texture whereby it operates, he cannot possibly know, is alike hard, as to make a part which he knows not how is made. Now it is certaine and beyond controversy that nature performs all her operations on the body by parts so minute and insensible that I thinke noe body will ever hope or pretend, even by the assistance of glasses or any other intervention, to come to a sight of them, and to tell us what organicall texture or what kinde offerment (for whether it be done by one or both of these ways is yet a question and like to be soe always notwithstanding all the endeavours of the most accurate dissections) separate any part of the juices in any of the viscera, or tell us of what liquors the particles of these juices are, or if this could be donne (which it is never like to be) would it at all contribute to the cure of the diseases of those very parts which we so perfectly knew.

Almighty God, to whose efficacious Word all things owe their original, abounding in his own glorious Essence with infinite goodness and fecundity, did in the beginning Create Man after his own likeness, Male and Female, created he them; the true distinction of which Sexes, consists merely in the different site of those parts of the body, wherein Generation necessarily requires a Diversity: for both Male and Female he impartially endued with the same, and altogether indifferent form of Soul, the Woman being possess’d of no less excellent Faculties of Mind, Reason, and Speech, than the Man, and equally with him aspiring to those Regions of Bliss and Glory, where there shall be no exception of Sex.

Almost everyone... seems to be quite sure that the differences between the methodologies of history and of the natural sciences are vast. For, we are assured, it is well known that in the natural sciences we start from observation and proceed by induction to theory. And is it not obvious that in history we proceed very differently? Yes, I agree that we proceed very differently. But we do so in the natural sciences as well.
In both we start from myths—from traditional prejudices, beset with error—and from these we proceed by criticism: by the critical elimination of errors. In both the role of evidence is, in the main, to correct our mistakes, our prejudices, our tentative theories—that is, to play a part in the critical discussion, in the elimination of error. By correcting our mistakes, we raise new problems. And in order to solve these problems, we invent conjectures, that is, tentative theories, which we submit to critical discussion, directed towards the elimination of error.

Although the cooking of food presents some unsolved problems, the quick warming of cooked food and the thawing of frozen food both open up some attractive uses. ... There is no important reason why the the housewife of the future should not purchase completely frozen meals at the grocery store just as she buys quick frozen vegetables. With a quick heating, high-frequency unit in her kitchen, food preparation from a pre-cooked, frozen meal becomes a simple matter.
[Predicting home kitchen appliances could be developed from the radionic tube employed to jam enemy radar in World War II.]

Among both the Northern and Eastern Hamites are to be found some of the most beautiful types of humanity.

Among the authorities it is generally agreed that the Earth is at rest in the middle of the universe, and they regard it as inconceivable and even ridiculous to hold the opposite opinion. However, if we consider it more closely the question will be seen to be still unsettled, and so decidedly not to be despised. For every apparent change in respect of position is due to motion of the object observed, or of the observer, or indeed to an unequal change of both.

Among the scenes which are deeply impressed on my mind, none exceed in sublimity the primeval forests undefaced by the hand of man; whether those of Brazil, where the powers of Life are predominant, or those of Tierra del Fuego, where Death and Decay prevail. Both are temples filled with the varied productions of the God of Nature: no one can stand in these solitudes unmoved, and not feel that there is more in man than the mere breath of his body.

An astronomer must be the wisest of men; his mind must be duly disciplined in youth; especially is mathematical study necessary; both an acquaintance with the doctrine of number, and also with that other branch of mathematics, which, closely connected as it is with the science of the heavens, we very absurdly call geometry, the measurement of the earth.

An atom-blaster is a good weapon, but it can point both ways.

And from this such small difference of eight minutes [of arc] it is clear why Ptolemy, since he was working with bisection [of the linear eccentricity], accepted a fixed equant point… . For Ptolemy set out that he actually did not get below ten minutes [of arc], that is a sixth of a degree, in making observations. To us, on whom Divine benevolence has bestowed the most diligent of observers, Tycho Brahe, from whose observations this eight-minute error of Ptolemy’s in regard to Mars is deduced, it is fitting that we accept with grateful minds this gift from God, and both acknowledge and build upon it. So let us work upon it so as to at last track down the real form of celestial motions (these arguments giving support to our belief that the assumptions are incorrect). This is the path I shall, in my own way, strike out in what follows. For if I thought the eight minutes in [ecliptic] longitude were unimportant, I could make a sufficient correction (by bisecting the [linear] eccentricity) to the hypothesis found in Chapter 16. Now, because they could not be disregarded, these eight minutes alone will lead us along a path to the reform of the whole of Astronomy, and they are the matter for a great part of this work.

André Weil suggested that there is a logarithmic law at work: first-rate people attract other first-rate people, but second-rate people tend to hire third-raters, and third-rate people hire fifth-raters. If a dean or a president is genuinely interested in building and maintaining a high-quality university (and some of them are), then he must not grant complete self-determination to a second-rate department; he must, instead, use his administrative powers to intervene and set things right. That’s one of the proper functions of deans and presidents, and pity the poor university in which a large proportion of both the faculty and the administration are second-raters; it is doomed to diverge to minus infinity.

Any demanding high technology tends to develop influential and dedicated constituencies of those who link its commercial success with both the public welfare and their own. Such sincerely held beliefs, peer pressures, and the harsh demands that the work i

Apart from the hostile influence of man, the organic and the inorganic world are … bound together by such mutual relations and adaptations as secure, if not the absolute permanence and equilibrium of both … at least a very slow and gradual succession of changes in those conditions. But man is everywhere a disturbing agent. Wherever he plants his foot, the harmonies of nature are turned to discords.

Architects who have aimed at acquiring manual skill without scholarship have never been able to reach a position of authority to correspond to their pains, while those who relied only upon theories and scholarship were obviously hunting the shadow, not the substance. But those who have a thorough knowledge of both, like men armed at all points, have the sooner attained their object and carried authority with them.

Arithmetic, as we shall see by and by, is overdone, in a certain sense, in our schools; just so far as the teaching is based upon the concrete, so far is it profitable; but when the book-makers begin to make it too abstract, as they very often do, it becomes a torture to both teacher and learners, or, at best, a branch of imaginary knowledge unconnected with real life.

Art and science coincide insofar as both aim to improve the lives of men and women. The latter normally concerns itself with profit, the former with pleasure. In the coming age, art will fashion our entertainment out of new means of productivity in ways that will simultaneously enhance our profit and maximize our pleasure.

As a boy I had liked both drawing and physics, and I always abhorred the role of being a spectator. In 1908, when I was 15, I designed, built and flew a toy model airplane which won the then-famous James Gordon Bennett Cup. By 16 I had discovered that design could be fun and profitable, and this lesson has never been lost on me.

As a child, I received instruction both in the Bible and in the Talmud. I am a Jew, but I am enthralled by the luminous figure of the Nazarene.

As a nation, we are too young to have true mythic heroes, and we must press real human beings into service. Honest Abe Lincoln the legend is quite a different character from Abraham Lincoln the man. And so should they be. And so should both be treasured, as long as they are distinguished. In a complex and confusing world, the perfect clarity of sports provides a focus for legitimate, utterly unambiguous support or disdain. The Dodgers are evil, the Yankees good. They really are, and have been for as long as anyone in my family can remember.

As an empiricist I continue to think of the conceptual scheme of science as a tool, ultimately, for predicting future experience in the light of past experience. Physical objects are conceptually imported into the situation as convenient intermediaries—not by definition in terms of experience, but simply as irreducible posits comparable, epistemologically, to the gods of Homer. For my part I do, qua lay physicist, believe in physical objects and not in Homer's gods; and I consider it a scientific error to believe otherwise. But in point of epistemological footing the physical objects and the gods differ only in degree and not in kind. Both sorts of entities enter our conception only as cultural posits. The myth of physical objects is epistemologically superior to most in that it has proved more efficacious than other myths as a device for working a manageable structure into the flux of experience.

As the ostensible effect of the heat … consists not in warming the surrounding bodies but in rendering the ice fluid, so, in the case of boiling, the heat absorbed does not warm surrounding bodies but converts the water into vapor. In both cases, considered as the cause of warmth, we do not perceive its presence: it is concealed, or latent, and I gave it the name of “latent heat.”

As was the case for Nobel's own invention of dynamite, the uses that are made of increased knowledge can serve both beneficial and potentially harmful ends. Increased knowledge clearly implies increased responsibility. We reject the notion advocated in some quarters that man should stop eating from the tree of knowledge, as if that were humanly possible.

Astronomy concerns itself with the whole of the visible universe, of which our earth forms but a relatively insignificant part; while Geology deals with that earth regarded as an individual. Astronomy is the oldest of the sciences, while Geology is one of the newest. But the two sciences have this in common, that to both are granted a magnificence of outlook, and an immensity of grasp denied to all the rest.

At bottom each “exact” science is, and must be speculative, and its chief tool of research, too rarely used with both courage and judgement, is the regulated imagination.

At fertilization, these two “haploid” nuclei are added together to make a “diploid” nucleus that now contains 2a, 2b and so on; and, by the splitting of each chromosome and the regulated karyokinetic separation of the daughter chromosomes, this double series is inherited by both of the primary blastomeres. In the resulting resting nuclei the individual chromosomes are apparently destroyed. But we have the strongest of indications that, in the stroma of the resting nucleus, every one of the chromosomes that enters the nucleus survives as a well-defined region; and as the cell prepares for its next division this region again gives rise to the same chromosome (Theory of the Individuality of the Chromosomes). In this way the two sets of chromosomes brought together at fertilization are inherited by all the cells of the new individual. It is only in the germinal cells that the so called reduction division converts the double series into a single one. Out of the diploid state, the haploid is once again generated.

At the entrance to the observatory Stjerneborg located underground, Tycho Brahe built a Ionic portal. On top of this were three sculptured lions. On both sides were inscriptions and on the backside was a longer inscription in gold letters on a porfyr stone: Consecrated to the all-good, great God and Posterity. Tycho Brahe, Son of Otto, who realized that Astronomy, the oldest and most distinguished of all sciences, had indeed been studied for a long time and to a great extent, but still had not obtained sufficient firmness or had been purified of errors, in order to reform it and raise it to perfection, invented and with incredible labour, industry, and expenditure constructed various exact instruments suitable for all kinds of observations of the celestial bodies, and placed them partly in the neighbouring castle of Uraniborg, which was built for the same purpose, partly in these subterranean rooms for a more constant and useful application, and recommending, hallowing, and consecrating this very rare and costly treasure to you, you glorious Posterity, who will live for ever and ever, he, who has both begun and finished everything on this island, after erecting this monument, beseeches and adjures you that in honour of the eternal God, creator of the wonderful clockwork of the heavens, and for the propagation of the divine science and for the celebrity of the fatherland, you will constantly preserve it and not let it decay with old age or any other injury or be removed to any other place or in any way be molested, if for no other reason, at any rate out of reverence to the creator’s eye, which watches over the universe. Greetings to you who read this and act accordingly. Farewell!

At the moment I am occupied by an investigation with Kirchoff which does not allow us to sleep. Kirchoff has made a totally unexpected discovery, inasmuch as he has found out the cause for the dark lines in the solar spectrum and can produce these lines artificially intensified both in the solar spectrum and in the continuous spectrum of a flame, their position being identical with that of Fraunhofer’s lines. Hence the path is opened for the determination of the chemical composition of the Sun and the fixed stars.

At the moment I am occupied by an investigation with Kirchoff which does not allow us to sleep. Kirchoff has made a totally unexpected discovery, inasmuch as he has found out the cause for the dark lines in the solar spectrum and can produce these lines artificially intensified both in the solar spectrum and in the continuous spectrum of a flame, their position being identical with that of Fraunhofer’s lines. Hence the path is opened for the determination of the chemical composition of the Sun and the fixed stars.

Bacteria are highly adaptable. They frequently change both morphologically and functionally. Their virulence is also an essentially fluctuating property, that increases or diminishes according to the conditions to which the pathogenic organism is subjected.

Basic research at universities comes in two varieties: research that requires big bucks and research that requires small bucks. Big bucks research is much like government research and in fact usually is government research but done for the government under contract. Like other government research, big bucks academic research is done to understand the nature and structure of the universe or to understand life, which really means that it is either for blowing up the world or extending life, whichever comes first. Again, that's the government's motivation. The universities' motivation for conducting big bucks research is to bring money in to support professors and graduate students and to wax the floors of ivy-covered buildings. While we think they are busy teaching and learning, these folks are mainly doing big bucks basic research for a living, all the while priding themselves on their terrific summer vacations and lack of a dress code.
Smalls bucks research is the sort of thing that requires paper and pencil, and maybe a blackboard, and is aimed primarily at increasing knowledge in areas of study that don't usually attract big bucks - that is, areas that don't extend life or end it, or both. History, political science, and romance languages are typically small bucks areas of basic research. The real purpose of small bucks research to the universities is to provide a means of deciding, by the quality of their small bucks research, which professors in these areas should get tenure.

Be temperate in wine, in eating, girls, & sloth;
Or the Gout will seize you and plague you both.

Because intelligence is our own most distinctive feature, we may incline to ascribe superior intelligence to the basic primate plan, or to the basic plan of the mammals in general, but this point requires some careful consideration. There is no question at all that most mammals of today are more intelligent than most reptiles of today. I am not going to try to define intelligence or to argue with those who deny thought or consciousness to any animal except man. It seems both common and scientific sense to admit that ability to learn, modification of action according to the situation, and other observable elements of behavior in animals reflect their degrees of intelligence and permit us, if only roughly, to compare these degrees. In spite of all difficulties and all the qualifications with which the expert (quite properly) hedges his conclusions, it also seems sensible to conclude that by and large an animal is likely to be more intelligent if it has a larger brain at a given body size and especially if its brain shows greater development of those areas and structures best developed in our own brains. After all, we know we are intelligent, even though we wish we were more so.

Behold the mighty dinosaur,
Famous in prehistoric lore,
Not only for his power and strength
But for his intellectual length.
You will observe by these remains
The creature had two sets of brains—
One in his head (the usual place),
The other at his spinal base.
Thus he could reason 'A priori'
As well as 'A posteriori'.
No problem bothered him a bit
He made both head and tail of it.
So wise was he, so wise and solemn,
Each thought filled just a spinal column.
If one brain found the pressure strong
It passed a few ideas along.
If something slipped his forward mind
'Twas rescued by the one behind.
And if in error he was caught
He had a saving afterthought.
As he thought twice before he spoke
He had no judgment to revoke.
Thus he could think without congestion
Upon both sides of every question.
Oh, gaze upon this model beast
Defunct ten million years at least.

Besides accustoming the student to demand, complete proof, and to know when he has not obtained it, mathematical studies are of immense benefit to his education by habituating him to precision. It is one of the peculiar excellencies of mathematical discipline, that the mathematician is never satisfied with à peu près. He requires the exact truth. Hardly any of the non-mathematical sciences, except chemistry, has this advantage. One of the commonest modes of loose thought, and sources of error both in opinion and in practice, is to overlook the importance of quantities. Mathematicians and chemists are taught by the whole course of their studies, that the most fundamental difference of quality depends on some very slight difference in proportional quantity; and that from the qualities of the influencing elements, without careful attention to their quantities, false expectation would constantly be formed as to the very nature and essential character of the result produced.

Biological diversity is unique in its importance to both developed and developing countries.

Biology is a science of three dimensions. The first is the study of each species across all levels of biological organization, molecule to cell to organism to population to ecosystem. The second dimension is the diversity of all species in the biosphere. The third dimension is the history of each species in turn, comprising both its genetic evolution and the environmental change that drove the evolution. Biology, by growing in all three dimensions, is progressing toward unification and will continue to do so.

Biology occupies a position among the sciences both marginal and central. Marginal because, the living world, constituting only a tiny and very “special” part of the universe, it does not seem likely that the study of living beings will ever uncover general laws applicable outside the biosphere. But if the ultimate aim of the whole of science is indeed, as I believe, to clarify man's relationship to the universe, then biology must be accorded a central position, since of all the disciplines it is the one that endeavours to go most directly to the heart of the problems that must be resolved before that of “human nature” can even be framed in other than metaphysical terms.

Boltzmann was both a wizard of a mathematician and a physicist of international renown. The magnitude of his output of scientific papers was positively unnerving. He would publish two, three, sometimes four monographs a year; each one was forbiddingly dense, festooned with mathematics, and as much as a hundred pages in length.

Both biological and cultural diversity are now severely threatened and working for their preservation is a critical task.

Both died, ignored by most; they neither sought nor found public favour, for high roads never lead there. Laurent and Gerhardt never left such roads, were never tempted to peruse those easy successes which, for strongly marked characters, offer neither allure nor gain. Their passion was for the search for truth; and, preferring their independence to their advancement, their convictions to their interests, they placed their love for science above that of their worldly goods; indeed above that for life itself, for death was the reward for their pains. Rare example of abnegation, sublime poverty that deserves the name nobility, glorious death that France must not forget!

Both history of nature and history of humanity are 'historical' and yet cannot dispense with uniformity. In both there is 'uniformity' ('science') as well as non-uniformity ('history'); in both 'history respects itself and 'history does not repeat itself. But, as even the history of humanity has its uniformitarian features, uniformity can still less be dispensed with in 'history' of nature, which, being one of the natural sciences, is less historical and, consequently, more uniformitarian.

Both religion and natural science require a belief in God for their activities, to the former He is the starting point, and to the latter the goal of every thought process. To the former He is the foundation, to the latter, the crown of the edifice of every generalized world view.

Both religion and science must preserve their autonomy and their distinctiveness. Religion is not founded on science nor is science an extension of religion. Each should possess its own principles, its pattern of procedures, its diversities of interpretation and its own conclusions.

Both Religion and science require faith in God. For believers, God is in the beginning, and for physicists He is at the end of all considerations.

Both science and art have to do with ordered complexity.

Both social and biosocial factors are necessary to interpret crosscultural studies, with the general proviso that one’s research interest determines which elements, in what combinations, are significant for the provision of understanding.

Both the man of science and the man of art live always at the edge of mystery, surrounded by it; both always, as to the measure of their creation, have had to do with the harmonization of what is new with what is familiar, with the balance between novelty and synthesis, with the struggle to make partial order in total chaos.

Both the physicist and the mystic want to communicate their knowledge, and when they do so with words their statements are paradoxical and full of logical contradictions.

But medicine has long had all its means to hand, and has discovered both a principle and a method, through which the discoveries made during a long period are many and excellent, while full discovery will be made, if the inquirer be competent, conduct his researches with knowledge of the discoveries already made, and make them his starting-point. But anyone who, casting aside and rejecting all these means, attempts to conduct research in any other way or after another fashion, and asserts that he has found out anything, is and has been victim of deception.

By the act of generation nothing more is done than to ferment the sperm of ye female by the sperm of ye male that it may thereby become fit nourishment for ye Embryo: ffor ye nourishment of all animals is prepared by ferment & the ferment is taken from animals of the same kind, & makes the nourishment subtile & spiritual. In adult animals the nourishm^t is fermented by the choler and pancreatic juice both w^ch come from the blood. The Embryo not being able to ferment its own nourishment w^ch comes from the mothers blood has it fermented by the sperm w^ch comes from ye fathers blood, & by this nourishment it swells, drops off from ye Ovarium & begins to grow with a life distinct from that of ye mother.

By the worldly standards of public life, all scholars in their work are of course oddly virtuous. They do not make wild claims, they do not cheat, they do not try to persuade at any cost, they appeal neither to prejudice nor to authority, they are often frank about their ignorance, their disputes are fairly decorous, they do not confuse what is being argued with race, politics, sex or age, they listen patiently to the young and to the old who both know everything. These are the general virtues of scholarship, and they are peculiarly the virtues of science.

Can I pay any higher tribute to a man [George Gaylord Simpson] than to state that his work both established a profession and sowed the seeds for its own revision? If Simpson had reached final truth, he either would have been a priest or would have chosen a dull profession. The history of life cannot be a dull profession.

Casting off the dark fog of verbal philosophy and vulgar medicine, which inculcate names alone ... I tried a series of experiments to explain more clearly many phenomena, particularly those of physiology. In order that I might subject as far as possible the reasonings of the Galenists and Peripatetics to sensory criteria, I began, after trying experiments, to write dialogues in which a Galenist adduced the better-known and stronger reasons and arguments; these a mechanist surgeon refuted by citing to the contrary the experiments I had tried, and a third, neutral interlocutor weighed the reasons advanced by both and provided an opportunity for further progress.

Certainlie these things agree,
The Priest, the Lawyer, & Death all three:
Death takes both the weak and the strong.
The lawyer takes from both right and wrong,
And the priest from living and dead has his Fee.

Chemistry affords two general methods of determining the constituent principles of bodies, the method of analysis, and that of synthesis. When, for instance, by combining water with alkohol, we form the species of liquor called, in commercial language, brandy or spirit of wine, we certainly have a right to conclude, that brandy, or spirit of wine, is composed of alkohol combined with water. We can produce the same result by the analytical method; and in general it ought to be considered as a principle in chemical science, never to rest satisfied without both these species of proofs. We have this advantage in the analysis of atmospherical air, being able both to decompound it, and to form it a new in the most satisfactory manner.

Chemists have made of phlogiston a vague principle which is not at all rigorously defined, and which, in consequence, adapts itself to all explanations in which it is wished it shall enter; sometimes it is free fire, sometimes it is fire combined with the earthy element; sometimes it passes through the pores of vessels, sometimes they are impenetrable to it; it explains both the causticity and non-causticity, transparency and opacity, colours and absence of colours. It is a veritable Proteus which changes its form every instant. It is time to conduct chemistry to a more rigorous mode of reasoning ... to distinguish fact and observation from what is systematic and hypothetical.

Christian Science … is the direct denial both of science and of Christianity, for Science rests wholly on the recognition of truth and Christianity on the recognition of pain.

Complex organisms cannot be construed as the sum of their genes, nor do genes alone build particular items of anatomy or behavior by them selves. Most genes influence several aspects of anatomy and behavior–as they operate through complex interactions with other genes and their products, and with environmental factors both within and outside the developing organism. We fall into a deep error, not just a harmful oversimplification, when we speak of genes ‘for’ particular items of anatomy or behavior.

Courtship, properly understood, is the process whereby both the male and the female are brought into that state of sexual tumescence which is a more or less necessary condition for sexual intercourse. The play of courtship cannot, therefore, be considered to be definitely brought to an end by the ceremony of marriage; it may more properly be regarded as the natural preliminary to every act of coitus.

Culture is activity of thought, and receptiveness to beauty and humane feeling. Scraps of information have nothing to do with it. A merely well informed man is the most useless bore on God’s earth. What we should aim at producing is men who possess both culture and expert knowledge in some special direction.

Cyberspace consists of transactions, relationships, and thought itself, arrayed like a standing wave in the web of our communications. Ours is a world that is both everywhere and nowhere, but it is not where bodies live. We are creating a world that all may enter without privilege or prejudice accorded by race, economic power, military force, or station of birth. We are creating a world where anyone, anywhere may express his or her beliefs, no matter how singular, without fear of being coerced into silence or conformity.

Dangerous, therefore, is it to take shelter under a tree, during a thunder-gust. It has been fatal to many, both men and beasts.

Darwin's characteristic perspicacity is nowhere better illustrated than in his prophecy of the reaction of the world of science. He admitted at once that it would be impossible to convince those older men '...whose minds are stocked with a multitude of facts, all viewed ... from a point of view directly opposite to mine ... A few naturalists endowed with much flexibility of mind and who have already begun to doubt the immutability of species, may be influenced by this volume; but I look with confidence to the young and rising naturalists, who will be able to view both sides with equal impartiality.

Discovery follows discovery, each both raising and answering questions, each ending a long search, and each providing the new instruments for a new search.

Does there truly exist an insuperable contradiction between religion and science? Can religion be superseded by science? The answers to these questions have, for centuries, given rise to considerable dispute and, indeed, bitter fighting. Yet, in my own mind there can be no doubt that in both cases a dispassionate consideration can only lead to a negative answer. What complicates the solution, however, is the fact that while most people readily agree on what is meant by ‘science,’ they are likely to differ on the meaning of ‘religion.’

Doubtless it is true that while consciousness is occupied in the scientific interpretation of a thing, which is now and again “a thing of beauty,” it is not occupied in the aesthetic appreciation of it. But it is no less true that the same consciousness may at another time be so wholly possessed by the aesthetic appreciation as to exclude all thought of the scientific interpretation. The inability of a man of science to take the poetic view simply shows his mental limitation; as the mental limitation of a poet is shown by his inability to take the scientific view. The broader mind can take both.

During my pre-college years I went on many trips with my father into the oil fields to visit their operations. … I puttered around the machine, electronics, and automobile shops while he carried on his business. Both of my parents are inveterate do-it-yourselfers, almost no task being beneath their dignity or beyond their ingenuity. Having picked up a keen interest in electronics from my father, I used to fix radios and later television sets for fun and spending money. I built my own hi-fi set and enjoyed helping friends with their amateur radio transmitters, but lost interest as soon as they worked.

Engineers apply the theories and principles of science and mathematics to research and develop economical solutions to practical technical problems. Their work is the link between scientific discoveries and commercial applications. Engineers design products, the machinery to build those products, the factories in which those products are made, and the systems that ensure the quality of the product and efficiency of the workforce and manufacturing process. They design, plan, and supervise the construction of buildings, highways, and transit systems. They develop and implement improved ways to extract, process, and use raw materials, such as petroleum and natural gas. They develop new materials that both improve the performance of products, and make implementing advances in technology possible. They harness the power of the sun, the earth, atoms, and electricity for use in supplying the Nation’s power needs, and create millions of products using power. Their knowledge is applied to improving many things, including the quality of health care, the safety of food products, and the efficient operation of financial systems.

Equations are Expressions of Arithmetical Computation, and properly have no place in Geometry, except as far as Quantities truly Geometrical (that is, Lines, Surfaces, Solids, and Proportions) may be said to be some equal to others. Multiplications, Divisions, and such sort of Computations, are newly received into Geometry, and that unwarily, and contrary to the first Design of this Science. For whosoever considers the Construction of a Problem by a right Line and a Circle, found out by the first Geometricians, will easily perceive that Geometry was invented that we might expeditiously avoid, by drawing Lines, the Tediousness of Computation. Therefore these two Sciences ought not to be confounded. The Ancients did so industriously distinguish them from one another, that they never introduced Arithmetical Terms into Geometry. And the Moderns, by confounding both, have lost the Simplicity in which all the Elegance of Geometry consists. Wherefore that is Arithmetically more simple which is determined by the more simple Equation, but that is Geometrically more simple which is determined by the more simple drawing of Lines; and in Geometry, that ought to be reckoned best which is geometrically most simple.