At last gleams of light have come, and I am almost convinced (quite contrary to opinion I started with) that species are not (it is like confessing a murder) immutable. Heaven forfend me from Lamarck nonsense of a “tendency to progression”, “adaptations from the slow willing of animals”, &c! But the conclusions I am led to are not widely different from his; though the means of change are wholly so. I think I have found out (here’s presumption!) the simple way by which species become exquisitely adapted to various ends.

Chemistry is one of those branches of human knowledge which has built itself upon methods and instruments by which truth can presumably be determined. It has survived and grown because all its precepts and principles can be re-tested at any time and anywhere. So long as it remained the mysterious alchemy by which a few devotees, by devious and dubious means, presumed to change baser metals into gold, it did not flourish, but when it dealt with the fact that 56 g. of fine iron, when heated with 32 g. of flowers of sulfur, generated extra heat and gave exactly 88 g. of an entirely new substance, then additional steps could be taken by anyone. Scientific research in chemistry, since the birth of the balance and the thermometer, has been a steady growth of test and observation. It has disclosed a finite number of elementary reagents composing an infinite universe, and it is devoted to their inter-reaction for the benefit of mankind.

Even if only one in a hundred of the ten billion suitable planets has actually got life well under way, there would be more than 100 million such planets. No, it is presumptuous to think that we are alone.

I have before mentioned mathematics, wherein algebra gives new helps and views to the understanding. If I propose these it is not to make every man a thorough mathematician or deep algebraist; but yet I think the study of them is of infinite use even to grown men; first by experimentally convincing them, that to make anyone reason well, it is not enough to have parts wherewith he is satisfied, and that serve him well enough in his ordinary course. A man in those studies will see, that however good he may think his understanding, yet in many things, and those very visible, it may fail him. This would take off that presumption that most men have of themselves in this part; and they would not be so apt to think their minds wanted no helps to enlarge them, that there could be nothing added to the acuteness and penetration of their understanding.

I think it would be a very rash presumption to think that nowhere else in the cosmos has nature repeated the strange experiment which she has performed on earth—that the whole purpose of creation has been staked on this one planet alone. It is probable that dotted through the cosmos there are other suns which provide the energy for life to attendant planets. It is apparent, however, that planets with just the right conditions of temperature, oxygen, water and atmosphere necessary for life are found rarely.
But uncommon as a habitable planet may be, non-terrestrial life exists, has existed and will continue to exist. In the absence of information, we can only surmise that the chance that it surpasses our own is as good as that it falls below our level.

If I were to suggest that between the Earth and Mars there is a china teapot revolving about the sun in an elliptical orbit, nobody would be able to disprove my assertion provided I were careful to add that the teapot is too small to be revealed even by our most powerful telescopes. But if I were to go on to say that, since my assertion cannot be disproved, it is intolerable presumption on the part of human reason to doubt it, I should rightly be thought to be talking nonsense. If, however, the existence of such a teapot were affirmed in ancient books, taught as the sacred truth every Sunday, and instilled into the minds of children at school, hesitation to believe in its existence would become a mark of eccentricity and entitle the doubter to the attentions of the psychiatrist in an enlightened age or of the Inquisitor in an earlier time.

In logic, A asserts and B denies. Assertions being proverbially untrue, the presumption would be in favor of B’s innocence were it not that denials are notoriously false.

In the same sense that our judicial system presumes us to be innocent until proven guilty, a medical care system may work best if it starts with the presumption that most people are healthy. Left to themselves, computers may try to do it in the opposite way, taking it as given that some sort of direct, continual, professional intervention is required all the time, in order to maintain the health of each citizen, and we will end up spending all our money on nothing but this.

Our sun is one of 100 billion stars in our galaxy. Our galaxy is one of billions of galaxies populating the universe. It would be the height of presumption to think that we are the only living things in that enormous immensity.

Science and engineering students presumably are left to learn about their literature in the same way they learn about sex.

The inexperienced and presumptuous band of medical tyros let loose upon the world destroys more of human life in one year than all the Robin Hoods, Cartouches, and Macheaths do in a century.

The whole inherent pride of human nature revolts at the idea that the lord of the creation is to be treated like any other natural object. No sooner does the naturalist discover the resemblance of some higher mammals, such as the ape, to man, than there is a general outcry against the presumptuous audacity that ventures to touch man in his inmost sanctuary. The whole fraternity of philosophers, who have never seen monkeys except in zoological gardens, at once mount the high horse, and appeal to the mind, the soul, to reason, to consciousness, and to all the rest of the innate faculties of man, as they are refracted in their own philosophical prisms.

Their vain presumption of knowing all can take beginning solely from their never having known anything; for if one has but once experienced the perfect knowledge of one thing, and truly tasted what it is to know, he shall perceive that of infinite other conclusions he understands not so much as one.

These Disciplines [mathematics] serve to inure and corroborate the Mind to a constant Diligence in Study; to undergo the Trouble of an attentive Meditation, and cheerfully contend with such Difficulties as lie in the Way. They wholly deliver us from a credulous Simplicity, most strongly fortify us against the Vanity of Scepticism, effectually restrain from a rash Presumption, most easily incline us to a due Assent, perfectly subject us to the Government of right Reason, and inspire us with Resolution to wrestle against the unjust Tyranny of false Prejudices. If the Fancy be unstable and fluctuating, it is to be poized by this Ballast, and steadied by this Anchor, if the Wit be blunt it is sharpened upon this Whetstone; if luxuriant it is pared by this Knife; if headstrong it is restrained by this Bridle; and if dull it is rouzed by this Spur. The Steps are guided by no Lamp more clearly through the dark Mazes of Nature, by no Thread more surely through the intricate Labyrinths of Philosophy, nor lastly is the Bottom of Truth sounded more happily by any other Line. I will not mention how plentiful a Stock of Knowledge the Mind is furnished from these, with what wholesome Food it is nourished, and what sincere Pleasure it enjoys. But if I speak farther, I shall neither be the only Person, nor the first, who affirms it; that while the Mind is abstracted and elevated from sensible Matter, distinctly views pure Forms, conceives the Beauty of Ideas, and investigates the Harmony of Proportions; the Manners themselves are sensibly corrected and improved, the Affections composed and rectified, the Fancy calmed and settled, and the Understanding raised and excited to more divine Contemplations. All which I might defend by Authority, and confirm by the Suffrages of the greatest Philosophers.

Without the suitable conditions life could not exist. But both life and its conditions set forth the operations of inscrutable Power. We know not its origin; we know not its end. And the presumption, if not the degradation, rests with those who place upon the throne of the universe a magnified image of themselves, and make its doings a mere colossal imitation of their own.