A fact is a simple statement that everyone believes. It is innocent, unless found guilty. A hypothesis is a novel suggestion that no one wants to believe. It is guilty until found effective.

A new theory is guilty until proven innocent, and the pre-existing theory innocent until proven guilty ... Continental drift was guilty until proven innocent.

But the Presidence of that mighty Power … its particular Agency and Concern therein: and its Purpose and Design … will more evidently appear, when I shall have proved … That the said Earth, though not indifferently and alike fertil in all parts of it, was yet generally much more fertil than ours is … That its Soil was more luxuriant, and teemed forth its Productions in far greater plenty and abundance than the present Earth does … That when Man was fallen, and had abandoned his primitive Innocence, the Case was much altered: and a far different Scene of Things presented; that generous Vertue, masculine Bravery, and prudent Circumspection which he was before Master of, now deserting him … and a strange imbecility immediately seized and laid hold of him: he became pusillanimous, and was easily ruffled with every little Passion within: supine, and as openly exposed to any Temptation or Assault from without. And now these exuberant Productions of the Earth became a continued Decoy and Snare unto him.

By what process of reasoning should the State of Texas be more concerned in the conviction of the guilty than in the acquittal of the innocent? [Urging the use of scopolamine “truth serum” to determine innocence.]

During this [book preparation] time attacks have not been wanting—we must always be prepared for them. If they grow out of a scientific soil, they cannot but be useful, by laying bare weak points and stimulating to their correction; but if they proceed from that soil, from which the lilies of innocence and the palms of conciliation should spring up, where, however, nothing but the marsh-trefoil of credulity and the poisonous water-hemlock of calumniation grow, they deserve no attention.

Every appearance in nature corresponds to some state of the mind, and that state of the mind can only be described by presenting that natural appearance as its picture. An enraged man is a lion, a cunning man is a fox, a firm man is a rock, a learned man is a torch. A lamb is innocence; a snake is subtle spite; flowers express to us the delicate affections. Light and darkness are our familiar expressions for knowledge and ignorance ; and heat for love. Visible distance behind and before us, is respectively our image of memory and hope.

In logic, A asserts and B denies. Assertions being proverbially untrue, the presumption would be in favor of B’s innocence were it not that denials are notoriously false.

It is sometimes asserted that a surgical operation is or should be a work of art … fit to rank with those of the painter or sculptor. … That proposition does not admit of discussion. It is a product of the intellectual innocence which I think we surgeons may fairly claim to possess, and which is happily not inconsistent with a quite adequate worldly wisdom.

Science, that gives man hope to live without lies
Or blast himself off the earth; curb science
Until morality catches up?
But look:
At present morality is running rapidly retrograde.
You’d have to turn science, too, back to the witch doctors,
the myth drunkards. Besides that,
Morality is not an end in itself; truth is an end.
To seek the truth is
better than good works, better than survival
Holier than innocence, and higher than love.

The double horror of two Japanese city names [Hiroshima and Nagasaki] grew for me into another kind of double horror; an estranging awareness of what the United States was capable of, the country that five years before had given me its citizenship; a nauseating terror at the direction the natural sciences were going. Never far from an apocalyptic vision of the world, I saw the end of the essence of mankind an end brought nearer, or even made, possible, by the profession to which I belonged. In my view, all natural sciences were as one; and if one science could no longer plead innocence, none could.

The only sure foundations of medicine are, an intimate knowledge of the human body, and observation on the effects of medicinal substances on that. The anatomical and clinical schools, therefore, are those in which the young physician should be formed. If he enters with innocence that of the theory of medicine, it is scarcely possible he should come out untainted with error. His mind must be strong indeed, if, rising above juvenile credulity, it can maintain a wise infidelity against the authority of his instructors, and the bewitching delusions of their theories.

The vulgar opinion, then, which, on health reasons, condemns vegetable food and so much praises animal food, being so ill-founded, I have always thought it well to oppose myself to it, moved both by experience and by that refined knowledge of natural things which some study and conversation with great men have given me. And perceiving now that such my constancy has been honoured by some learned and wise physicians with their authoritative adhesion (della autorevole sequela), I have thought it my duty publicly to diffuse the reasons of the Pythagorean diet, regarded as useful in medicine, and, at the same time, as full of innocence, of temperance, and of health. And it is none the less accompanied with a certain delicate pleasure, and also with a refined and splendid luxury (non è privo nemmeno d’una certa delicate voluttà e d’un lusso gentile e splendido ancora), if care and skill be applied in selection and proper supply of the best vegetable food, to which the fertility and the natural character of our beautiful country seem to invite us. For my part I have been so much the more induced to take up this subject, because I have persuaded myself that I might be of service to intending diet-reformers, there not being, to my knowledge, any book of which this is the sole subject, and which undertakes exactly to explain the origin and the reasons of it.

This shall be the test of innocence—if I can hear a taunt, and look out on this friendly moon, pacing the heavens in queenlike majesty, with the accustomed yearning.