... I should think that anyone who considered it more reasonable for the whole universe to move in order to let the Earth remain fixed would be more irrational than one who should climb to the top of your cupola just to get a view of the city and its environs, and then demand that the whole countryside should revolve around him so that he would not have to take the trouble to turn his head.

Between the frontiers of the three super-states Eurasia, Oceania, and Eastasia, and not permanently in possession of any of them, there lies a rough quadrilateral with its corners at Tangier, Brazzaville, Darwin, and Hongkong. These territories contain a bottomless reserve of cheap labour. Whichever power controls equatorial Africa, or the Middle East or Southern India or the Indonesian Archipelago, disposes also of the bodies of hundreds of millions of ill-paid and hardworking coolies, expended by their conquerors like so much coal or oil in the race to turn out more armaments, to capture more territory, to control more labour, to turn out more armaments, to capture more territory, to control…
Thus George Orwell—in his only reference to the less-developed world.
I wish I could disagree with him. Orwell may have erred in not anticipating the withering of direct colonial controls within the “quadrilateral” he speaks about; he may not quite have gauged the vehemence of urges to political self-assertion. Nor, dare I hope, was he right in the sombre picture of conscious and heartless exploitation he has painted. But he did not err in predicting persisting poverty and hunger and overcrowding in 1984 among the less privileged nations.
I would like to live to regret my words but twenty years from now, I am positive, the less-developed world will be as hungry, as relatively undeveloped, and as desperately poor, as today.

Copernicus, who rightly did condemn
This eldest systeme, form’d a wiser scheme;
In which he leaves the Sun at Rest, and rolls
The Orb Terrestial on its proper Poles;
Which makes the Night and Day by this Career,
And by its slow and crooked Course the Year.
The famous Dane, who oft the Modern guides,
To Earth and Sun their Provinces divides:
The Earth's Rotation makes the Night and Day,
The Sun revolving through th'Eccliptic Way
Effects the various seasons of the Year,
Which in their Turn for happy Ends appear.
This Scheme or that, which pleases best, embrace,
Still we the Fountain of their Motion trace.
Kepler asserts these Wonders may be done
By the Magnetic Vertue of the Sun,
Which he, to gain his End, thinks fit to place
Full in the Center of that mighty Space,
Which does the Spheres, where Planets roll, include,
And leaves him with Attractive Force endu'd.
The Sun, thus seated, by Mechanic Laws,
The Earth, and every distant Planet draws;
By which Attraction all the Planets found
Within his reach, are turn'd in Ether round.

Dass die bis jetzt unzerlegten chemischen Elemente absolut unzerlegbare Stoffe seien, ist gegenwärtig mindestens sehr unwahrscheinlich. Vielmehr scheint es, dass die Atome der Elemente nicht die letzten, sondern nur die näheren Bestandtheile der Molekeln sowohl der Elemente wie der Verbindungen bilden, die Molekeln oder Molecule als Massentheile erster, die Atome als solche zweiter Ordnung anzusehen sind, die ihrerseits wiederum aus Massentheilchen einer dritten höheren Ordnung bestehen werden.
That the as yet undivided chemical elements are absolutely irreducible substances, is currently at least very unlikely. Rather it seems, that the atoms of elements are not the final, but only the immediate constituents of the molecules of both the elements and the compounds—the Molekeln or molecule as foremost division of matter, the atoms being considered as second order, in turn consisting of matter particles of a third higher order.
[Speculating in 1870, on the existence of subatomic particles, in opening remark of the paper by which he became established as co-discoverer of the Periodic Law.]

Dinosaur: I plan to use punctuated equilibrium to turn this zit into a third eye.
Catbert: That's not a natural advantage. You'd better stay away from the fitter dinosaurs.

Naturae vero rerum vis atque maiestas in omnibus momentis fide caret si quis modo partes eius ac non totam conplectatur animo.
The power and majesty of the nature of the universe at every turn lacks credence if one’s mind embraces parts of it only and not the whole.

Nautae etiam mare legentes, cum beneficium claritatis solis in tempore nubilo non sentiunt, aut etiam cum caligne nocturnarum tenebrarum mundus obvolvitur, et ignorant in quem mundi cardinem prora tendat, acum super mangentem ponunt, quae circulariter circumvolvitur usque dum, ejus motu cessante.
Mariners at sea, when, through cloudy weather in the day which hides the sun, or through the darkness of night, they lose knowlege of the quarter of the world to which they are sailing, touch a needle with a magnet, which will turn round till, on its motion ceasing, its point will be directed towards the north.

Quelquefois, par exemple, je me figure que je suis suspendu en l’air, et que j’y demeure sans mouvement, pendant que la Terre tourne sous moi en vingt-quatre heures. Je vois passer sous mes yeux tous ces visages différents, les uns blancs, les autres noirs, les autres basanés, les autres olivâtres. D’abord ce sont des chapeaux et puis des turbans, et puis des têtes chevelues, et puis des têtes rasées; tantôt des villes à clochers, tantôt des villes à longues aiguilles qui ont des croissants, tantôt des villes à tours de porcelaine, tantôt de grands pays qui n’ont que des cabanes; ici de vastes mers, là des déserts épouvantables; enfin, toute cette variété infinie qui est sur la surface de la Terre.
Sometimes, for instance, I imagine that I am suspended in the air, and remain there motionless, while the earth turns under me in four-and-twenty hours. I see pass beneath me all these different countenances, some white, others black, others tawny, others olive-colored. At first they wear hats, and then turbans, then heads with long hair, then heads shaven; sometimes towns with steeples, sometimes towns with long spires, which have crescents, sometimes towns with porcelain towers, sometimes extensive countries that have only huts; here wide seas; there frightful deserts; in short, all this infinite variety on the surface of the earth.

Qui ergo munitam vult habere navem habet etiam acum jaculo suppositam. Rotabitur enim et circumvolvetur acus, donec cuspis acus respiciat orientem sicque comprehendunt quo tendere debeant nautaw cum Cynosura latet in aeris turbatione; quamvis ad occasum numquam tendat, propter circuli brevitatem.
If then one wishes a ship well provided with all things, then one must have also a needle mounted on a dart. The needle will be oscillated and turn until the point of the needle directs itself to the East* [North], thus making known to sailors the route which they should hold while the Little Bear is concealed from them by the vicissitudes of the atmosphere; for it never disappears under the horizon because of the smallness of the circle it describes.

Sed tamen salis petrae. VI. Part V. NOV. CORVLI. ET V. sulphuris, et sic facies toniitrum et coruscationem: sic facies artificium.
But, however, of saltpetre take six parts, live of young willow (charcoal), and five of sulphur, and so you will make thunder and lightning, and so you will turn the trick.
Bacon’s recipe for Gunpowder, partly expressed as an anagram in the original Latin.

A bewildering assortment of (mostly microscopic) life-forms has been found thriving in what were once thought to be uninhabitable regions of our planet. These hardy creatures have turned up in deep, hot underground rocks, around scalding volcanic vents at the bottom of the ocean, in the desiccated, super-cold Dry Valleys of Antarctica, in places of high acid, alkaline, and salt content, and below many meters of polar ice. ... Some deep-dwelling, heat-loving microbes, genetic studies suggest, are among the oldest species known, hinting that not only can life thrive indefinitely in what appear to us totally alien environments, it may actually originate in such places.

A closer look at the course followed by developing theory reveals for a start that it is by no means as continuous as one might expect, but full of breaks and at least apparently not along the shortest logical path. Certain methods often afforded the most handsome results only the other day, and many might well have thought that the development of science to infinity would consist in no more than their constant application. Instead, on the contrary, they suddenly reveal themselves as exhausted and the attempt is made to find other quite disparate methods. In that event there may develop a struggle between the followers of the old methods and those of the newer ones. The former's point of view will be termed by their opponents as out-dated and outworn, while its holders in turn belittle the innovators as corrupters of true classical science.

A country grows in history not only because of the heroism of its troops on the field of battle, it grows also when it turns to justice and to right for the conservation of its interests.

A discovery is like falling in love and reaching the top of a mountain after a hard climb all in one, an ecstasy not induced by drugs but by the revelation of a face of nature that no one has seen before and that often turns out to be more subtle and wonderful than anyone had imagined.

A discussion between Haldane and a friend began to take a predictable turn. The friend said with a sigh, “It’s no use going on. I know what you will say next, and I know what you will do next.” The distinguished scientist promptly sat down on the floor, turned two back somersaults, and returned to his seat. “There,” he said with a smile. “That’s to prove that you’re not always right.”

A fear of intellectual inadequacy, of powerlessness before the tireless electronic wizards, has given rise to dozens of science-fiction fantasies of computer takeovers. ... Other scientists too are apprehensive. D. Raj Reddy, a computer scientist at Pittsburgh’s Carnegie-Mellon University, fears that universally available microcomputers could turn into formidable weapons. Among other things, says Reddy, sophisticated computers in the wrong hands could begin subverting a society by tampering with people’s relationships with their own computers—instructing the other computers to cut off telephone, bank and other services, for example.

A fire-mist and a planet,
A crystal and a cell,
A jellyfish and a saurian,
And caves where the cavemen dwell;
Then a sense of law and beauty,
And a face turned from the clod—
Some call it Evolution,
And others call it God.

A game is on, at the other end of this infinite distance, and heads or tails will turn up. What will you wager? According to reason you cannot leave either; according to reason you cannot leave either undone... Yes, but wager you must; there is no option, you have embarked on it. So which will you have. Come. Since you must choose, let us see what concerns you least. You have two things to lose: truth and good, and two things to stake: your reason and your will, your knowledge and your happiness. And your nature has two things to shun: error and misery. Your reason does not suffer by your choosing one more than the other, for you must choose. That is one point cleared. But your happiness? Let us weigh gain and loss in calling heads that God is. Reckon these two chances: if you win, you win all; if you lose, you lose naught. Then do not hesitate, wager that He is.

A good deal of my research in physics has consisted in not setting out to solve some particular problem, but simply examining mathematical quantities of a kind that physicists use and trying to fit them together in an interesting way, regardless of any application that the work may have. It is simply a search for pretty mathematics. It may turn out later to have an application. Then one has good luck. At age 78.

A historical fact is rather like the flamingo that Alice in Wonderland tried to use as a croquet mallet. As soon as she got its neck nicely straightened out and was ready to hit the ball, it would turn and look at her with a puzzled expression, and any biographer knows that what is called a “fact” has a way of doing the same.

A man with a conviction is a hard man to change. Tell him you disagree and he turns away. Show him facts or figures and he questions your sources. Appeal to logic and he fails to see your point.

Absolute space, that is to say, the mark to which it would be necessary to refer the earth to know whether it really moves, has no objective existence…. The two propositions: “The earth turns round” and “it is more convenient to suppose the earth turns round” have the same meaning; there is nothing more in the one than in the other.

Abstruse mathematical researches … are … often abused for having no obvious physical application. The fact is that the most useful parts of science have been investigated for the sake of truth, and not for their usefulness. A new branch of mathematics, which has sprung up in the last twenty years, was denounced by the Astronomer Royal before the University of Cambridge as doomed to be forgotten, on account of its uselessness. Now it turns out that the reason why we cannot go further in our investigations of molecular action is that we do not know enough of this branch of mathematics.

After two days in the hospital, I took a turn for the nurse.

Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.

Alas! That partial Science should approve
The sly rectangle’s too licentious love!
From three bright Nymphs the wily wizard burns;-
Three bright-ey’d Nymphs requite his flame by turns.
Strange force of magic skill! Combined of yore.

All frescoes are as high finished as miniatures or enamels, and they are known to be unchangeable; but oil, being a body itself, will drink or absorb very little colour, and changing yellow, and at length brown, destroys every colour it is mixed with, especially every delicate colour. It turns every permanent white to a yellow and brown putty, and has compelled the use of that destroyer of colour, white lead, which, when its protecting oil is evaporated, will become lead again. This is an awful thing to say to oil painters ; they may call it madness, but it is true. All the genuine old little pictures, called cabinet pictures, are in fresco and not in oil. Oil was not used except by blundering ignorance till after Vandyke’s time ; but the art of fresco painting being lost, oil became a fetter to genius and a dungeon to art.

All interesting issues in natural history are questions of relative frequency, not single examples. Everything happens once amidst the richness of nature. But when an unanticipated phenomenon occurs again and again–finally turning into an expectation–then theories are overturned.

All knowledge is good. It is impossible to say any fragment of knowledge, however insignificant or remote from one’s ordinary pursuits, may not some day be turned to account.

All our knowledge merely helps us to die a more painful death than the animals that know nothing. A day will come when science will turn upon its error and no longer hesitate to shorten our woes. A day will come when it will dare and act with certainty; when life, grown wiser, will depart silently at its hour, knowing that it has reached its term.

All the different classes of beings which taken together make up the universe are, in the ideas of God who knows distinctly their essential gradations, only so many ordinates of a single curve so closely united that it would be impossible to place others between any two of them, since that would imply disorder and imperfection. Thus men are linked with the animals, these with the plants and these with the fossils which in turn merge with those bodies which our senses and our imagination represent to us as absolutely inanimate. And, since the law of continuity requires that when the essential attributes of one being approximate those of another all the properties of the one must likewise gradually approximate those of the other, it is necessary that all the orders of natural beings form but a single chain, in which the various classes, like so many rings, are so closely linked one to another that it is impossible for the senses or the imagination to determine precisely the point at which one ends and the next begins?all the species which, so to say, lie near the borderlands being equivocal, at endowed with characters which might equally well be assigned to either of the neighboring species. Thus there is nothing monstrous in the existence zoophytes, or plant-animals, as Budaeus calls them; on the contrary, it is wholly in keeping with the order of nature that they should exist. And so great is the force of the principle of continuity, to my thinking, that not only should I not be surprised to hear that such beings had been discovered?creatures which in some of their properties, such as nutrition or reproduction, might pass equally well for animals or for plants, and which thus overturn the current laws based upon the supposition of a perfect and absolute separation of the different orders of coexistent beings which fill the universe;?not only, I say, should I not be surprised to hear that they had been discovered, but, in fact, I am convinced that there must be such creatures, and that natural history will perhaps some day become acquainted with them, when it has further studied that infinity of living things whose small size conceals them for ordinary observation and which are hidden in the bowels of the earth and the depth of the sea.

All the summer long is the swallow a most instructive pattern of unwearied industry and affection; for, from morning to night, while there is a family to be supported, she spends the whole day in skimming close to the ground, and exerting the most sudden turns and quick evolutions. Avenues, and long walks under hedges, and pasture-fields, and mown meadows where cattle graze, are her delight, especially if there are trees interspersed; because in such spots insects most abound. When a fly is taken a smart snap from her bill is heard, resembling the noise at the shutting of a watch case; but the motion of the mandibles are too quick for the eye.

America’s technology has turned in upon itself; its corporate form makes it the servant of profits, not the servant of human needs.

Among those whom I could never pursuade to rank themselves with idlers, and who speak with indignation of my morning sleeps and nocturnal rambles, one passes the day in catching spiders, that he may count their eyes with a microscope; another exhibits the dust of a marigold separated from the flower with a dexterity worthy of Leuwenhoweck himself. Some turn the wheel of electricity; some suspend rings to a lodestone, and find that what they did yesterday, they can do again to-day.—Some register the changes of the wind, and die fully convinced that the wind is changeable.—There are men yet more profound, who have heard that two colorless liquors may produce a color by union, and that two cold bodies will grow hot of they are mingled: they mingle them, and produce the effect expected, say it is strange, and mingle them again.

An educated person is one who has learned that information almost always turns out to be at best incomplete and very often false, misleading, fictitious, mendacious—just dead wrong.

An engineer passing a pond heard a frog say, “If you kiss me, I’ll turn into a beautiful princess.” He picked up the frog, looked at it, and put it in his pocket. The frog said, “Why didn’t you kiss me?” Replied the engineer, “Look, I’m an engineer. I don’t have time for a girlfriend, but a talking frog is cool.”

An invention that is quickly accepted will turn out to be a rather trivial alteration of something that has already existed.

And this is a miracle of nature in part known, namely, that iron follows the part of a magnet that touches it, and flies from the other part of the same magnet. And the iron turns itself after moving to the part of the heavens conformed to the part of the magnet which it touched.

Andrade [who was looking after wartime inventions] is like an inverted Micawber, waiting for something to turn down.

Any experiment may be regarded as forming an individual of a 'population' of experiments which might be performed under the same conditions. A series of experiments is a sample drawn from this population.
Now any series of experiments is only of value in so far as it enables us to form a judgment as to the statistical constants of the population to which the experiments belong. In a great number of cases the question finally turns on the value of a mean, either directly, or as the mean difference between the two qualities.
If the number of experiments be very large, we may have precise information as to the value of the mean, but if our sample be small, we have two sources of uncertainty:— (I) owing to the 'error of random sampling' the mean of our series of experiments deviates more or less widely from the mean of the population, and (2) the sample is not sufficiently large to determine what is the law of distribution of individuals.

Any one who has studied the history of science knows that almost every great step therein has been made by the “anticipation of Nature,” that is, by the invention of hypotheses, which, though verifiable, often had very little foundation to start with; and, not unfrequently, in spite of a long career of usefulness, turned out to be wholly erroneous in the long run.

Any urine that turns black is so extremely malignant that I do not know anyone who has micturated black urine and survived.

Apart from the hostile influence of man, the organic and the inorganic world are … bound together by such mutual relations and adaptations as secure, if not the absolute permanence and equilibrium of both … at least a very slow and gradual succession of changes in those conditions. But man is everywhere a disturbing agent. Wherever he plants his foot, the harmonies of nature are turned to discords.

ARSENIC, n. A kind of cosmetic greatly affected by the ladies, whom it greatly affects in turn.

As evolutionary time is measured, we have only just turned up and have hardly had time to catch breath, still marveling at our thumbs, still learning to use the brand-new gift of language. Being so young, we can be excused all sorts of folly and can permit ourselves the hope that someday, as a species, we will begin to grow up.

As for the earth, out of it comes bread, but underneath it is turned up as by fire. Its stones are the place of sapphires, and it has dust of gold.

As historians, we refuse to allow ourselves these vain speculations which turn on possibilities that, in order to be reduced to actuality, suppose an overturning of the Universe, in which our globe, like a speck of abandoned matter, escapes our vision and is no longer an object worthy of our regard. In order to fix our vision, it is necessary to take it such as it is, to observe well all parts of it, and by indications infer from the present to the past.

As scientists the two men were contrasting types—Einstein all calculation, Rutherford all experiment ... There was no doubt that as an experimenter Rutherford was a genius, one of the greatest. He worked by intuition and everything he touched turned to gold. He had a sixth sense.
(Reminiscence comparing his friend, Ernest Rutherford, with Albert Einstein, whom he also knew.)

Astronomy and Pure Mathematics are the magnetic poles toward which the compass of my mind ever turns.

Astronomy teaches the correct use of the sun and the planets. These may be put on a frame of little sticks and turned round. This causes the tides. Those at the ends of the sticks are enormously far away. From time to time a diligent searching of the sticks reveals new planets. The orbit of the planet is the distance the stick goes round in going round. Astronomy is intensely interesting; it should be done at night, in a high tower at Spitzbergen. This is to avoid the astronomy being interrupted. A really good astronomer can tell when a comet is coming too near him by the warning buzz of the revolving sticks.

At first men try with magic charms
To fertilize the earth,
To keep their flocks and herds from harm
And bring new young to birth.

Then to capricious gods they turn
To save from fire or flood;
Their smoking sacrifices burn
On altars red with blood.

Next bold philosopher and sage
A settled plan decree
And prove by thought or sacred page
What Nature ought to be.

But Nature smiles—a Sphinx-like smile
Watching their little day
She waits in patience for a while—
Their plans dissolve away.

Then come those humbler men of heart
With no completed scheme,
Content to play a modest part,
To test, observe, and dream.

Till out of chaos come in sight
Clear fragments of a Whole;
Man, learning Nature’s ways aright
Obeying, can control.

At night I would return home, set out a lamp before me, and devote myself to reading and writing. Whenever sleep overcame me or I became conscious of weakening, I would turn aside to drink a cup of wine, so that my strength would return to me. Then I would return to reading. And whenever sleep seized me I would see those very problems in my dream; and many questions became clear to me in my sleep. I continued in this until all of the sciences were deeply rooted within me and I understood them as is humanly possible. Everything which I knew at the time is just as I know it now; I have not added anything to it to this day. Thus I mastered the logical, natural, and mathematical sciences, and I had now reached the science.

Available energy is energy which we can direct into any desired channel. Dissipated energy is energy which we cannot lay hold of and direct at pleasure, such as the energy of the confused agitation of molecules which we call heat. Now, confusion, like the correlative term order, is not a property of material things in themselves, but only in relation to the mind which perceives them. A memorandum-book does not, provided it is neatly written, appear confused to an illiterate person, or to the owner who understands it thoroughly, but to any other person able to read it appears to be inextricably confused. Similarly the notion of dissipated energy could not occur to a being who could not turn any of the energies of nature to his own account, or to one who could trace the motion of every molecule and seize it at the right moment. It is only to a being in the intermediate stage, who can lay hold of some forms of energy while others elude his grasp, that energy appears to be passing inevitably from the available to the dissipated state.

Beware when the great God lets loose a thinker on this planet. Then all things are at risk. ... There is not a piece of science, but its flank may be turned to-morrow.

Biology is a science of three dimensions. The first is the study of each species across all levels of biological organization, molecule to cell to organism to population to ecosystem. The second dimension is the diversity of all species in the biosphere. The third dimension is the history of each species in turn, comprising both its genetic evolution and the environmental change that drove the evolution. Biology, by growing in all three dimensions, is progressing toward unification and will continue to do so.

But when you come right down to it, the reason that we did this job is because it was an organic necessity. If you are a scientist you cannot stop such a thing. If you are a scientist you believe that it is good to find out how the world works; that it is good to find out what the realities are; that it is good to turn over to mankind at large the greatest possible power to control the world and to deal with it according to its lights and values.
Regarding the atomic bomb project.

But, as Bacon has well pointed out, truth is more likely to come out of error, if this is clear and definite, than out of confusion, and my experience teaches me that it is better to hold a well-understood and intelligible opinion, even if it should turn out to be wrong, than to be content with a muddle-headed mixture of conflicting views, sometimes miscalled impartiality, and often no better than no opinion at all.

But, contrary to the lady’s prejudices about the engineering profession, the fact is that quite some time ago the tables were turned between theory and applications in the physical sciences. Since World War II the discoveries that have changed the world are not made so much in lofty halls of theoretical physics as in the less-noticed labs of engineering and experimental physics. The roles of pure and applied science have been reversed; they are no longer what they were in the golden age of physics, in the age of Einstein, Schrödinger, Fermi and Dirac.

By a recent estimate, nearly half the bills before the U.S. Congress have a substantial science-technology component and some two-thirds of the District of Columbia Circuit Court’s case load now involves review of action by federal administrative agencies; and more and more of such cases relate to matters on the frontiers of technology.
If the layman cannot participate in decision making, he will have to turn himself over, essentially blind, to a hermetic elite. … [The fundamental question becomes] are we still capable of self-government and therefore freedom?
Margaret Mead wrote in a 1959 issue of Daedalus about scientists elevated to the status of priests. Now there is a name for this elevation, when you are in the hands of—one hopes—a benevolent elite, when you have no control over your political decisions. From the point of view of John Locke, the name for this is slavery.

Certainly, it is heaven upon earth, to have a man's mind move in charity, rest in providence, and turn upon the poles of truth.

Cleveland, even now I can remember
Cause the Cuyahoga River
Goes smokin’ through my dreams
Burn on, big river, burn on
Burn on, big river, burn on
Now the Lord can make you tumble
And the Lord can make you turn
And the Lord can make you overflow
But the Lord can’t make you burn.

Consider the hateful brew compounded with gleaming, deadly white lead whose fresh colour is like milk…. Over the victim’s jaws and in the grooves of the gums is plastered an astringent froth, and the furrow of the tongue turns rough on either side, and the depth of the throat grows somewhat dry, and from the pernicious venom follows a dry retching and hawking, for this affliction is severe; meanwhile his spirit sickens and he is worn out with mortal suffering. His body too grows chill, while sometimes his eyes behold strange illusions or else he drowses; nor can he bestir his limbs as heretofore, and he succumbs to the overmastering fatigue.

Cuvier … brings the void to life again, without uttering abracadabras, he excavates a fragment of gypsum, spies a footprint and shouts: “Look!” And suddenly the marbles are teeming with creatures, the dead come to life again, the world turns!

Data isn't information. ... Information, unlike data, is useful. While there’s a gulf between data and information, there’s a wide ocean between information and knowledge. What turns the gears in our brains isn't information, but ideas, inventions, and inspiration. Knowledge—not information—implies understanding. And beyond knowledge lies what we should be seeking: wisdom.

During a conversation with the writer in the last weeks of his life, Sylvester remarked as curious that notwithstanding he had always considered the bent of his mind to be rather analytical than geometrical, he found in nearly every case that the solution of an analytical problem turned upon some quite simple geometrical notion, and that he was never satisfied until he could present the argument in geometrical language.

Each of us has read somewhere that in New Guinea pidgin the word for 'piano' is (I use English spelling) 'this fellow you hit teeth belonging to him he squeal all same pig'. I am inclined to doubt whether this expression is authentic; it looks just like the kind of thing a visitor to the Islands would facetiously invent. But I accept 'cut grass belong head belong me' for 'haircut' as genuine... Such phrases seem very funny to us, and make us feel very superior to the ignorant foreigners who use long winded expressions for simple matters. And then it is our turn to name quite a simple thing, a small uncomplicated molecule consisting of nothing more than a measly 11 carbons, seven hydrogens, one nitrogen and six oxygens. We sharpen our pencils, consult our rule books and at last come up with 3-[(1, 3- dihydro-1, 3-dioxo-2H-isoindol-2-yl) oxy]-3-oxopropanoic acid. A name like that could drive any self-respecting Papuan to piano-playing.

Early in my school career, I turned out to be an incorrigible disciplinary problem. I could understand what the teacher was saying as fast as she could say it, I found time hanging heavy, so I would occasionally talk to my neighbor. That was my great crime, I talked in school.

Edward [Teller] isn’t the cloistered kind of scientist. He gets his ideas in conversation and develops them by trying them out on people. We were coming back from Europe on the Ile de France and I was standing in the ship’s nightclub when he came up and said, 'Freddie, I think I have an idea.’ It was something he’d just thought of about magnetohydrodynamics. I was a bachelor then and I’d located several good-looking girls on the ship, but I knew what I had to do, so I disappeared and started working on the calculations. I’d get something finished and start prowling on the deck again when Edward would turn up out of the night and we’d walk the deck together while he talked and I was the brick wall he was bouncing these things off of. By the end of the trip we had a paper. He’d had the ideas, and I’d done some solving of equations. But he insisted that we sign in alphabetical order, which put my name first.

Einstein’s 1905 paper came out and suddenly changed people’s thinking about space-time. We’re again [2007] in the middle of something like that. When the dust settles, time—whatever it may be—could turn out to be even stranger and more illusory than even Einstein could imagine.

Electricity is often called wonderful, beautiful; but it is so only in common with the other forces of nature. The beauty of electricity or of any other force is not that the power is mysterious, and unexpected, touching every sense at unawares in turn, but that it is under law, and that the taught intellect can even govern it largely. The human mind is placed above, and not beneath it, and it is in such a point of view that the mental education afforded by science is rendered super-eminent in dignity, in practical application and utility; for by enabling the mind to apply the natural power through law, it conveys the gifts of God to man.

England and all civilised nations stand in deadly peril of not having enough to eat. As mouths multiply, food resources dwindle. Land is a limited quantity, and the land that will grow wheat is absolutely dependent on difficult and capricious natural phenomena... I hope to point a way out of the colossal dilemma. It is the chemist who must come to the rescue of the threatened communities. It is through the laboratory that starvation may ultimately be turned into plenty... The fixation of atmospheric nitrogen is one of the great discoveries, awaiting the genius of chemists.

Environmentalists may get off on climate porn, but most people just turn away. 'If it was really so bad, they'd do something,' says one colleague, without specifying who 'they' are. The human tendency to convince yourself that everything is OK, because no one else is worried, is deeply ingrained.

Euclid alone
Has looked on Beauty bare.
He turned away at once;
Far too polite to stare.

Everything around us is filled with mystery and magic. I find this no cause for despair, no reason to turn for solace to esoteric formulae or chariots of gods. On the contrary, our inability to find easy answers fills me with a fierce pride in our ambivalent biology … with a constant sense of wonder and delight that we should be part of anything so profound.

Everything is like a purse—there may be money in it, and we can generally say by the feel of it whether there is or is not. Sometimes, however, we must turn it inside out before we can be quite sure whether there is anything in it or no. When I have turned a proposition inside out, put it to stand on its head, and shaken it, I have often been surprised to find how much came out of it.

Evolution triumphs because it turns to natural selection, the plodding accumulation of error.

Evolution: At the Mind's Cinema
I turn the handle and the story starts:
Reel after reel is all astronomy,
Till life, enkindled in a niche of sky,
Leaps on the stage to play a million parts.
Life leaves the slime and through all ocean darts;
She conquers earth, and raises wings to fly;
Then spirit blooms, and learns how not to die,-
Nesting beyond the grave in others' hearts.
I turn the handle: other men like me
Have made the film: and now I sit and look
In quiet, privileged like Divinity
To read the roaring world as in a book.
If this thy past, where shall they future climb,
O Spirit, built of Elements and Time?

First, there is the power of the Wind, constantly exerted over the globe.... Here is an almost incalculable power at our disposal, yet how trifling the use we make of it! It only serves to turn a few mills, blow a few vessels across the ocean, and a few trivial ends besides. What a poor compliment do we pay to our indefatigable and energetic servant!

For centuries knowledge meant proven knowledge…. Einstein’s results again turned the tables and now very few philosophers or scientists still think that scientific knowledge is, or can be, proven knowledge. But few realize that with this the whole classical structure of intellectual values falls in ruins and has to be replaced.

For many centuries chemists labored to change lead into precious gold, and eventually found that precious uranium turned to lead without any human effort at all.

For, dear me, why abandon a belief
Merely because it ceases to be true.
Cling to it long enough, and not a doubt
It will turn true again, for so it goes.
Most of the change we think we see in life
Is due to truths being in and out of favour.

Formula for breakthroughs in research: Take young researchers, put them together in virtual seclusion, give them an unprecedented degree of freedom and turn up the pressure by fostering competitiveness.

Fractal is a word invented by Mandelbrot to bring together under one heading a large class of objects that have [played] … an historical role … in the development of pure mathematics. A great revolution of ideas separates the classical mathematics of the 19th century from the modern mathematics of the 20th. Classical mathematics had its roots in the regular geometric structures of Euclid and the continuously evolving dynamics of Newton. Modern mathematics began with Cantor’s set theory and Peano’s space-filling curve. Historically, the revolution was forced by the discovery of mathematical structures that did not fit the patterns of Euclid and Newton. These new structures were regarded … as “pathological,” .… as a “gallery of monsters,” akin to the cubist paintings and atonal music that were upsetting established standards of taste in the arts at about the same time. The mathematicians who created the monsters regarded them as important in showing that the world of pure mathematics contains a richness of possibilities going far beyond the simple structures that they saw in Nature. Twentieth-century mathematics flowered in the belief that it had transcended completely the limitations imposed by its natural origins.
Now, as Mandelbrot points out, … Nature has played a joke on the mathematicians. The 19th-century mathematicians may not have been lacking in imagination, but Nature was not. The same pathological structures that the mathematicians invented to break loose from 19th-century naturalism turn out to be inherent in familiar objects all around us.

From an entertainment point of view, the Solar System has been a bust. None of the planets turns out to have any real-estate potential, and most of them are probably even useless for filming Dune sequels.

From that night on, the electron—up to that time largely the plaything of the scientist—had clearly entered the field as a potent agent in the supplying of man's commercial and industrial needs… The electronic amplifier tube now underlies the whole art of communications, and this in turn is at least in part what has made possible its application to a dozen other arts. It was a great day for both science and industry when they became wedded through the development of the electronic amplifier tube.

Genetics has always turned out to be much more complicated than it seemed reasonable to imagine. Biology is not like physics. The more we know, the less it seems that there is one final explanation waiting to be discovered.

Genetics has enticed a great many explorers during the past two decades. They have labored with fruit-flies and guinea-pigs, with sweet peas and corn, with thousands of animals and plants in fact, and they have made heredity no longer a mystery but an exact science to be ranked close behind physics and chemistry in definiteness of conception. One is inclined to believe, however, that the unique magnetic attraction of genetics lies in the vision of potential good which it holds for mankind rather than a circumscribed interest in the hereditary mechanisms of the lowly species used as laboratory material. If man had been found to be sharply demarcated from the rest of the occupants of the world, so that his heritage of physical form, of physiological function, and of mental attributes came about in a superior manner setting him apart as lord of creation, interest in the genetics of the humbler organisms—if one admits the truth—would have flagged severely. Biologists would have turned their attention largely to the ways of human heredity, in spite of the fact that the difficulties encountered would have rendered progress slow and uncertain. Since this was not the case, since the laws ruling the inheritance of the denizens of the garden and the inmates of the stable were found to be applicable to prince and potentate as well, one could shut himself up in his laboratory and labor to his heart's content, feeling certain that any truth which it fell to his lot to discover had a real human interest, after all.

Great fleas have little fleas upon their backs to bite 'em,
And little fleas have lesser fleas, and so ad infinitum.
And the great fleas themselves, in turn have, greater fleas to go on;
While these again have greater still, and greater still, and so on.
[He was imitating: 'So, naturalists observe, a flea Has smaller fleas that on him prey; And these have smaller still to bite 'em; And so proceed ad infinitum.' Poetry, a Rhapsody, by Jonathan Swift.]

Groups do not have experiences except insofar as all their members do. And there are no experiences... that all the members of a scientific community must share in the course of a [scientific] revolution. Revolutions should be described not in terms of group experience but in terms of the varied experiences of individual group members. Indeed, that variety itself turns out to play an essential role in the evolution of scientific knowledge.

Hence dusky Iron sleeps in dark abodes,
And ferny foliage nestles in the nodes;
Till with wide lungs the panting bellows blow,
And waked by fire the glittering torrents flow;
Quick whirls the wheel, the ponderous hammer falls,
Loud anvils ring amid the trembling walls,
Strokes follow strokes, the sparkling ingot shines,
Flows the red slag, the lengthening bar refines;
Cold waves, immersed, the glowing mass congeal,
And turn to adamant the hissing Steel.

Here are a few things to keep in mind the next time ants show up in the potato salad. The 8,800 known species of the family Formicidae make up from 10% to 15% of the world's animal biomass, the total weight of all fauna. They are the most dominant social insect in the world, found almost everywhere except in the polar regions. Ants turn more soil than earthworms; they prune, weed and police most of the earth's carrion. Among the most gregarious of creatures, they are equipped with a sophisticated chemical communications system. To appreciate the strength and speed of this pesky invertebrate, consider that a leaf cutter the size of a man could run repeated four-minute miles while carrying 750 lbs. of potato salad.

His Majesty has, with great skill, constructed a cart, containing a corn mill, which is worked by the motion of the carriage. He has also contrived a carriage of such a magnitude as to contain several apartments, with a hot bath; and it is drawn by a single elephant. This movable bath is extremely useful, and refreshing on a journey. … He has also invented several hydraulic machines, which are worked by oxen. The pulleys and wheels of some of them are so adjusted that a single ox will at once draw water out of two wells, and at the same time turn a millstone.

His [Edison’s] greatest invention was that of the industrial research laboratory, turning out inventions as a business.

History is primarily a socio-psychological science. In the conflict between the old and the new tendencies in historical investigation... we are at the turn of the stream, the parting of the ways in historical science.

How to start on my adventure—how to become a forester—was not so simple. There were no schools of Forestry in America. … Whoever turned his mind toward Forestry in those days thought little about the forest itself and more about its influences, and about its influence on rainfall first of all. So I took a course in meteorology, which has to do with weather and climate. and another in botany, which has to do with the vegetable kingdom—trees are unquestionably vegetable. And another in geology, for forests grow out of the earth. Also I took a course in astronomy, for it is the sun which makes trees grow. All of which is as it should be, because science underlies the forester’s knowledge of the woods. So far I was headed right. But as for Forestry itself, there wasn’t even a suspicion of it at Yale. The time for teaching Forestry as a profession was years away.

Human consciousness is just about the last surviving mystery. A mystery is a phenomenon that people don't know how to think about—yet. There have been other great mysteries: the mystery of the origin of the universe, the mystery of life and reproduction, the mystery of the design to be found in nature, the mysteries of time, space, and gravity. These were not just areas of scientific ignorance, but of utter bafflement and wonder. We do not yet have the final answers to any of the questions of cosmology and particle physics, molecular genetics and evolutionary theory, but we do know how to think about them. The mysteries haven't vanished, but they have been tamed. They no longer overwhelm our efforts to think about the phenomena, because now we know how to tell the misbegotten questions from the right questions, and even if we turn out to be dead wrong about some of the currently accepted answers, we know how to go about looking for better answers. With consciousness, however, we are still in a terrible muddle. Consciousness stands alone today as a topic that often leaves even the most sophisticated thinkers tongue-tied and confused. And, as with all the earlier mysteries, there are many who insist—and hope—that there will never be a demystification of consciousness.

I am aware that those hateful persons called Original Researchers now maintain that Raleigh was not the man; but to them I turn a deaf ear.
On who offered his coat for Queen Elizabeth I.

I am turned into a sort of machine for observing facts and grinding out conclusions.

I argued that it was important not to place too much reliance on any single piece of experimental evidence. It might turn out to be misleading, as the 5.1 Å reflection undoubtedly was. Jim was a little more brash, stating that no good model ever accounted for all the facts, since some data was bound to be misleading if not plain wrong. A theory that did fit all the data would have been “carpentered” to do so and would thus be open to suspicion.

I call upon the scientific community in our country, those who gave us nuclear weapons, to turn their great talents now to the cause of mankind and world peace, to give us the means of rendering those nuclear weapons impotent and obsolete.
About his proposed Strategic Defense Initiative, later to be known as 'Star Wars.')

I called it ignose, not knowing which carbohydrate it was. This name was turned down by my editor. 'God-nose' was not more successful, so in the end 'hexuronic acid' was agreed upon. To-day the substance is called 'ascorbic acid' and I will use this name.

I don’t know whether there is a finite set of basic laws of physics or whether there are infinite sets of structure like an infinite set of Chinese boxes. Will the electron turn out to have an interior structure? I wish I knew!

I feel, sometimes, as the renaissance man must have felt in finding new riches at every point and in the certainty that unexplored areas of knowledge and experience await at every turn.

I grew up in love with science, asking the same questions all children ask as they try to codify the world to find out what makes it work. “Who is the smartest person in the world?” and “Where is the tallest mountain in the world?” turned into questions like, “How big is the universe?” and “What is it that makes us alive?”

I had a Meccano set with which I “played” endlessly. Meccano which was invented by Frank Hornby around 1900, is called Erector Set in the US. New toys (mainly Lego) have led to the extinction of Meccano and this has been a major disaster as far as the education of our young engineers and scientists is concerned. Lego is a technically trivial plaything and kids love it partly because it is so simple and partly because it is seductively coloured. However it is only a toy, whereas Meccano is a real engineering kit and it teaches one skill which I consider to be the most important that anyone can acquire: This is the sensitive touch needed to thread a nut on a bolt and tighten them with a screwdriver and spanner just enough that they stay locked, but not so tightly that the thread is stripped or they cannot be unscrewed. On those occasions (usually during a party at your house) when the handbasin tap is closed so tightly that you cannot turn it back on, you know the last person to use the washroom never had a Meccano set.

I have never seen the Philosopher's Stone that turns lead into Gold, but I have known the pursuit of it turn a Man's Gold into Lead.

I have turned my attention from technological progress to life, from the civilized to the wild.

I heard … xenon was a good anesthesia. … I thought, “How can xenon, which doesn’t form any chemical compounds, serve as a general anesthetic? … I lay awake at night for a few minutes before going to sleep, and during the next couple of weeks each night I would think, “…how do anesthetic agents work?" Then I forgot to do it after a while, but I’d trained my unconscious mind to keep this question alive and to call [it] to my consciousness whenever a new idea turned up…. So seven years went by. [One day I] put my feet up on the desk and started reading my mail, and here was a letter from George Jeffrey … an x-ray crystallographer, on his determination of the structure of a hydrate crystal. Immediately I sat up, took my feet off the desk, and said, “I understand anesthesia!” … I spent a year [and] determined the structure of chloroform hydrate, and then I wrote my paper published in June of 1961.

I know well there are those who would have the Study of Nature restrained wholly to Observations; without ever proceeding further. But due Consideration, and a deeper Insight into Things, would soon have undeceived and made them sensible of their error. Assuredly, that man who should spend his whole life in amassing together stone, timber, and other materials for building, without ever at the making any use, or raising any fabrick out of them, might well be reputed very fantastic and extravagant. And a like censure would be his due, who should be perpetually heaping up of natural collections without design. building a structure of philosophy out of them, or advancing some propositions that might turn to the benefit and advantage of the world. This is in reality the true and only proper end of collections, of observations, and natural history: and they are of no manner of use or value without it.

I noticed affixed to a laboratory door the following words: “Les théories passent. Le Grenouille reste. [The theories pass. The frog remains.] &mdashJean Rostand, Carnets d’un biologiste.” There is a risk that in the less severe discipline of criticism the result may turn out to be different; the theories will remain but the frog may disappear.

I recall my own emotions: I had just been initiated into the mysteries of the complex number. I remember my bewilderment: here were magnitudes patently impossible and yet susceptible of manipulations which lead to concrete results. It was a feeling of dissatisfaction, of restlessness, a desire to fill these illusory creatures, these empty symbols, with substance. Then I was taught to interpret these beings in a concrete geometrical way. There came then an immediate feeling of relief, as though I had solved an enigma, as though a ghost which had been causing me apprehension turned out to be no ghost at all, but a familiar part of my environment.

I remember my father had a sermon he used to preach when we were in Florida, in which he gave a reference to the Southern Cross—about the stars, the colors, in the Southern Cross, which thrilled me very much. I must have been around 5 years old. ... Now, it turns out that the Southern Cross itself does have one red star, together with three blue ones.

I searched along the changing edge
Where, sky-pierced now the cloud had broken.
I saw no bird, no blade of wing,
No song was spoken.
I stood, my eyes turned upward still
And drank the air and breathed the light.
Then, like a hawk upon the wind,
I climbed the sky, I made the flight.

I shall never forget the sight. The vessel of crystallization was three quarters full of slightly muddy water—that is, dilute water-glass—and from the sandy bottom there strove upwards a grotesque little landscape of variously colored growths: a confused vegetation of blue, green, and brown shoots which reminded one of algae, mushrooms, attached polyps, also moss, then mussels, fruit pods, little trees or twigs from trees, here, and there of limbs. It was the most remarkable sight I ever saw, and remarkable not so much for its profoundly melancholy nature. For when Father Leverkühn asked us what we thought of it and we timidly answered him that they might be plants: “No,” he replied, “they are not, they only act that way. But do not think the less of them. Precisely because they do, because they try as hard as they can, they are worthy of all respect.”
It turned out that these growths were entirely unorganic in their origin; they existed by virtue of chemicals from the apothecary's shop.

I talk to myself through the computer. I ask myself questions, leave things to be looked at again, things that you would do with a notepad. It turns out today that it’s much better today to do with a personal computer rather than a notepad.

I think people get it upside down when they say the unambiguous is the reality and the ambiguous is merely uncertainty about what is really unambiguous. Let’s turn it around the other way: the ambiguous is the reality and the unambiguous is merely a special case of it, where we finally manage to pin down some very special aspect.

I think that the formation of [DNA's] structure by Watson and Crick may turn out to be the greatest developments in the field of molecular genetics in recent years.

I think this case will be remembered because it is the first case of this sort since we stopped trying people in America for witchcraft, because here we have done our best to turn back the tide that has sought to force itself upon this modern world, of testing every fact in science by a religious dictum.

I turn my eyes to the schools & universities of Europe
And there behold the loom of Locke whose woof rages dire,
Washed by the water-wheels of Newton. Black the cloth
In heavy wreaths folds over every nation; cruel works
Of many wheels I view, wheel without wheel, with cogs tyrannic
Moving by compulsion each other: not as those in Eden, which
Wheel within wheel in freedom revolve, in harmony & peace.

I want to turn women loose on the environmental crisis…. Nobody knows more about pollution when detergents back up in the sink.

I was a kind of a one-man army. I could solder circuits together, I could turn out things on the lathe, I could work with rockets and balloons. I’m a kind of a hybrid between an engineer and a physicist and astronomer.

I was sitting writing at my textbook but the work did not progress; my thoughts were elsewhere. I turned my chair to the fire and dozed. Again the atoms were gambolling before my eyes. This time the smaller groups kept modestly in the background. My mental eye, rendered more acute by the repeated visions of the kind, could now distinguish larger structures of manifold confirmation: long rows, sometimes more closely fitted together all twining and twisting in snake like motion. But look! What was that? One of the snakes had seized hold of its own tail, and the form whirled mockingly before my eyes. As if by a flash of lightning I awoke; and this time also I spent the rest of the night in working out the rest of the hypothesis. Let us learn to dream, gentlemen, then perhaps we shall find the truth... But let us beware of publishing our dreams till they have been tested by waking understanding.

I wasn’t aware of Chargaff’s rules when he said them, but the effect on me was quite electric because I realized immediately that if you had this sort of scheme that John Griffith was proposing, of adenine being paired with thymine, and guanine being paired with cytosine, then you should get Chargaff’s rules.
I was very excited, but I didn’t actually tell Chargaff because it was something I was doing with John Griffith. There was a sort of musical comedy effect where I forgot what the bases were and I had to go to the library to check, and I went back to John Griffith to find out which places he said. Low and behold, it turned out that John Griffith’s ideas fitted in with Chargaff’s rules!
This was very exciting, and we thought “ah ha!” and we realized—I mean what anyone who is familiar with the history of science ought to realize—that when you have one-to-one ratios, it means things go to together. And how on Earth no one pointed out this simple fact in those years, I don’t know.

I work for perfection, for perfection's sake. I don't care what the external reasons are. And it's much more like a ballerina on opening night. You've done what you've got to do. When you go out, the purpose is to turn a perfect turn. You are not thinking about the future of the company, you are not thinking about your future, you're not thinking about the critics, it is you and the perfect turn.
[Describing his task of repairing the Hubble Space Telescope.]

I … decided that the challenge of starting with a completely clean slate and mapping out a program that would influence astronomy for fifty years was just more than I could turn down.