[Vestiges begins] from principles which are at variance with all sober inductive truth. The sober facts of geology shuffled, so as to play a rogue’s game; phrenology (that sinkhole of human folly and prating coxcombry); spontaneous generation; transmutation of species; and I know not what; all to be swallowed, without tasting and trying, like so much horse-physic!! Gross credulity and rank infidelity joined in unlawful marriage, and breeding a deformed progeny of unnatural conclusions!

[Describing the effects of over-indulgence in wine:]
But most too passive, when the blood runs low
Too weakly indolent to strive with pain,
And bravely by resisting conquer fate,
Try Circe's arts; and in the tempting bowl
Of poisoned nectar sweet oblivion swill.
Struck by the powerful charm, the gloom dissolves
In empty air; Elysium opens round,
A pleasing frenzy buoys the lightened soul,
And sanguine hopes dispel your fleeting care;
And what was difficult, and what was dire,
Yields to your prowess and superior stars:
The happiest you of all that e'er were mad,
Or are, or shall be, could this folly last.
But soon your heaven is gone: a heavier gloom
Shuts o'er your head; and, as the thundering stream,
Swollen o'er its banks with sudden mountain rain,
Sinks from its tumult to a silent brook,
So, when the frantic raptures in your breast
Subside, you languish into mortal man;
You sleep, and waking find yourself undone,
For, prodigal of life, in one rash night
You lavished more than might support three days.
A heavy morning comes; your cares return
With tenfold rage. An anxious stomach well
May be endured; so may the throbbing head;
But such a dim delirium, such a dream,
Involves you; such a dastardly despair
Unmans your soul, as maddening Pentheus felt,
When, baited round Citheron's cruel sides,
He saw two suns, and double Thebes ascend.

Lyveris to-forn us
Useden to marke
For selkouthes that thei seighen,
Hir sones for to teche;
And helden it an heigh science
Hir wittes to knowe.
Ac thorugh hir science soothly
Was nevere no soule y-saved,
Ne broght by hir bokes
To blisse ne to joye;
For alle hir kynde knowynges
Come but of diverse sightes.
Patriarkes and prophetes
Repreveden hir science,
And seiden hir wordes and hir wisdomes
Nas but a folye
And to the clergie of Crist
Counted it but a trufle.
Our ancestors in olden days used to record
The strange things they saw, and teach them to their sons;
And they held it a high science, to have knowledge of such things.
But no soul was ever saved by all that science,
Nor brought by books into eternal bliss;
Their science was only a series of sundry observations.
So patriarchs and prophets disapproved of their science,
And said their so-called words of wisdom were but folly—
And compared with Christian philosophy, a contemptible thing.

A barbarous practice, the inconsistency, folly, and injury of which no words can sufficiently describe.
Condemning the use of mercurial medicines.

A fool’s brain digests philosophy into folly, science into superstition, and art into pedantry. Hence University education.

As evolutionary time is measured, we have only just turned up and have hardly had time to catch breath, still marveling at our thumbs, still learning to use the brand-new gift of language. Being so young, we can be excused all sorts of folly and can permit ourselves the hope that someday, as a species, we will begin to grow up.

Between men of different studies and professions, may be observed a constant reciprocation of reproaches. The collector of shells and stones derides the folly of him who pastes leaves and flowers upon paper, pleases himself with colours that are perceptibly fading, and amasses with care what cannot be preserved. The hunter of insects stands amazed that any man can waste his short time upon lifeless matter, while many tribes of animals yet want their history. Every one is inclined not only to promote his own study, but to exclude all others from regard, and having heated his imagination with some favourite pursuit, wonders that the rest of mankind are not seized with the same passion.

Broadly speaking, we are in the middle of a race between human skill as a means and human folly as an end.

EXPERIENCE, n. The wisdom that enables us to recognize as an undesirable old acquaintance the folly that we have already embraced.

For nearly twelve years I travelled and lived mostly among uncivilised or completely savage races, and I became convinced that they all possessed good qualities, some of them in a very remarkable degree, and that in all the great characteristics of humanity they are wonderfully like ourselves. Some, indeed, among the brown Polynesians especially, are declared by numerous independent and unprejudiced observers, to be physically, mentally, and intellectually our equals, if not our superiors; and it has always seemed to me one of the disgraces of our civilisation that these fine people have not in a single case been protected from contamination by the vices and follies of our more degraded classes, and allowed to develope their own social and political organislll under the advice of some of our best and wisest men and the protection of our world-wide power. That would have been indeed a worthy trophy of our civilisation. What we have actually done, and left undone, resulting in the degradation and lingering extermination of so fine a people, is one of the most pathetic of its tragedies.

Good lawyers know that in many cases where the decisions are correct, the reasons that are given to sustain them may be entirely wrong. This is a thousand times more likely to be true in the practice of medicine than in that of the law, and hence the impropriety, not to say the folly, in spending your time in the discussion of medical belief and theories of cure that are more ingenious and seductive than they are profitable.

History … celebrates the battlefields that kill us, but keeps silent on the crop fields that sustain us. It knows the bastards of kings, she doesn’t know the origin of wheat. This is the way of human folly.

Humanity has the stars in its future, and that future is too important to be lost under the burden of juvenile folly and ignorant superstition.

I grow increasingly aware, and in more ways than expected that I am at the center of my own field; and whether it be folly or wisdom, it is a very pleasant feeling.

I have been branded with folly and madness for attempting what the world calls impossibilities, and even from the great engineer, the late James Watt, who said ... that I deserved hanging for bringing into use the high-pressure engine. This has so far been my reward from the public; but should this be all, I shall be satisfied by the great secret pleasure and laudable pride that I feel in my own breast from having been the instrument of bringing forward new principles and new arrangements of boundless value to my country, and however much I may be straitened in pecuniary circumstances, the great honour of being a useful subject can never be taken from me, which far exceeds riches.

If the [Vestiges] be true, the labours of sober induction are in vain; religion is a lie; human law is a mass of folly, and a base injustice; morality is moonshine; our labours for the black people of Africa were works of madmen; and man and woman are only better beasts!

In spite of ignorance, folly and passion, the scientific method has won field after field since the days of Galileo. From mechanics it passed to physics, from physics to biology, from biology to psychology, where it is slowly adapting itself to unfamiliar ground.

In the fight which we have to wage incessantly against ignorance and quackery among the masses and follies of all sorts among the classes, diagnosis, not drugging, is our chief weapon of offence. Lack of systematic personal training in the methods of the recognition of disease leads to the misapplication of remedies, to long courses of treatment when treatment is useless, and so directly to that lack of confidence in our methods which is apt to place us in the eyes of the public on a level with empirics and quacks.

It has been said that astronomy is a humbling and character building experience. There is perhaps no better demonstration of the folly of human conceits than this distant image of our tiny world. To me, it underscores our responsibility to deal more kindly with one another, and to preserve and cherish the pale blue dot, the only home we’ve ever known.

It is a curious and painful fact that almost all the completely futile treatments that have been believed in during the long history of medical folly have been such as caused acute suffering to the patient. When anesthetics were discovered, pious people considered them an attempt to evade the will of God. It was pointed out, however, that when God extracted Adam's rib He put him into a deep sleep. This proved that anesthetics are all right for men; women, however, ought to suffer, because of the curse of Eve.

It is a great folly to wish to be exclusively wise.

It is a sign of our power, and our criminal folly, that we can pollute the vast ocean and are doing so.

It is characteristic of our age to endeavour to replace virtues by technology. That is to say, wherever possible we strive to use methods of physical or social engineering to achieve goals which our ancestors thought attainable only by the training of character. Thus, we try so far as possible to make contraception take the place of chastity, and anaesthetics to take the place of fortitude; we replace resignation by insurance policies and munificence by the Welfare State. It would be idle romanticism to deny that such techniques and institutions are often less painful and more efficient methods of achieving the goods and preventing the evils which unaided virtue once sought to achieve and avoid. But it would be an equal and opposite folly to hope that the take-over of virtue by technology may one day be complete, so that the necessity for the laborious acquisition of the capacity for rational choice by individuals can be replaced by the painless application of the fruits of scientific discovery over the whole field of human intercourse and enterprise.

It is folly to think that we can destroy one species and ecosystem after another and not affect humanity. When we save species, we’re actually saving ourselves.

It is folly to use as one's guide in the selection of fundamental science the criterion of utility. Not because (scientists)... despise utility. But because. .. useful outcomes are best identified after the making of discoveries, rather than before.
Concerning the allocation of research funds.

It is reported of Margaret Fuller that she said she accepted the universe. “Gad, she'd better!” retorted Carlyle. Carlyle himself did not accept the universe in a very whole-hearted manner. Looking up at the midnight stars, he exclaimed: “A sad spectacle! If they be inhabited, what a scope for misery and folly; if they be na inhabited, what a waste of space!”

It is the utmost folly to denounce capital. To do so is to undermine civilization, for capital is the first requisite of every social gain, educational, ecclesiastical, political, or other.

It would be the height of folly—and self-defeating—to think that things never heretofore done can be accomplished without means never heretofore tried.

Knowledge and wisdom are indeed not identical; and every man’s experience must have taught him that there may be much knowledge with little wisdom, and much wisdom with little knowledge. But with imperfect knowledge it is difficult or impossible to arrive at right conclusions. Many of the vices, many of the miseries, many of the follies and absurdities by which human society has been infested and disgraced may be traced to a want of knowledge.

Let us not, in the pride of our superior knowledge, turn with contempt from the follies of our predecessors. The study of the errors into which great minds have fallen in the pursuit of truth can never be uninstructive.

Oh, my dear Kepler, how I wish that we could have one hearty laugh together. Here, at Padua, is the principal professor of philosophy, whom I have repeatedly and urgently requested to look at the moon and planets through my glass, [telescope] which he pertinaciously refuses to do. Why are you not here? what shouts of laughter we should have at this glorious folly! and to hear the professor of philosophy at Pisa laboring before the grand duke with logical arguments, as if with magical incantations, to charm the new planets out of the sky.

That radioactive elements created by us are found in nature is an astounding event in the history of the earth. And of the Human race. To fail to consider its importance and its consequences would be a folly for which humanity would have to pay a terrible price. When public opinion has been created in the countries concerned and among all the nations, an opinion informed of the dangers involved in going on with the tests and led by the reason which this information imposes, then the statesmen may reach an agreement to stop the experiments.

The folly of mistaking a paradox for a discovery, a metaphor for a proof, a torrent of verbiage for a spring of capital truths, and oneself for an oracle, is inborn in us.

The hours of Folly are measured by the clock, but of Wisdom no clock can measure.

The language of the street is always strong. What can describe the folly and emptiness of scolding like the word jawing?

The news today about ‘Atomic bombs’ is so horrifying one is stunned. The utter folly of these lunatic physicists to consent to do such work for war-purposes: calmly plotting the destruction of the world!

The Reader may here observe the Force of Numbers, which can be successfully applied, even to those things, which one would imagine are subject to no Rules. There are very few things which we know, which are not capable of being reduc’d to a Mathematical Reasoning, and when they cannot, it’s a sign our Knowledge of them is very small and confus’d; and where a mathematical reasoning can be had, it’s as great folly to make use of any other, as to grope for a thing in the dark when you have a Candle standing by you.

The skein of human continuity must often become this tenuous across the centuries (hanging by a thread, in the old cliché), but the circle remains unbroken if I can touch the ink of Lavoisier’s own name, written by his own hand. A candle of light, nurtured by the oxygen of his greatest discovery, never burns out if we cherish the intellectual heritage of such unfractured filiation across the ages. We may also wish to contemplate the genuine physical thread of nucleic acid that ties each of us to the common bacterial ancestor of all living creatures, born on Lavoisier’s ancienne terre more than 3.5 billion years ago—and never since disrupted, not for one moment, not for one generation. Such a legacy must be worth preserving from all the guillotines of our folly.

The world makes up for all its follies and injustices by being damnably sentimental.

The worst thing that will probably happen—in fact is already well underway—is not energy depletion, economic collapse, conventional war, or the expansion of totalitarian governments. As terrible as these catastrophes would be for us, they can be repaired in a few generations. The one process now going on that will take millions of years to correct is loss of genetic and species diversity by the destruction of natural habitats. This is the folly our descendants are least likely to forgive us.

There are few enough people with sufficient independence to see the weaknesses and follies of their contemporaries and remain themselves untouched by them. And these isolated few usually soon lose their zeal for putting things to rights when they have come face to face with human obduracy. Only to a tiny minority is it given to fascinate their generation by subtle humour and grace and to hold the mirror up to it by the impersonal agency of art. To-day I salute with sincere emotion the supreme master of this method, who has delighted–and educated–us all.

There is a moral or metaphysical part of nature as well as a physical. A man who denies this is deep in the mire of folly. ’Tis the crown and glory of organic science that it does through final cause, link material and moral; and yet does not allow us to mingle them in our first conception of laws, and our classification of such laws, whether we consider one side of nature or the other. You have ignored this link; and, if I do not mistake your meaning, you have done your best in one or two pregnant cases to break it. Were it possible (which, thank God, it is not) to break it, humanity, in my mind, would suffer a damage that might brutalize it, and sink the human race into a lower grade of degradation than any into which it has fallen since its written records tell us of its history.

We find that whole communities suddenly fix their minds upon one object, and go mad in its pursuit; that millions of people become simultaneously impressed with one delusion, and run after it, till their attention is caught by some new folly more captivating than the first.

What a curious picture it is to find man, homo sapiens, of divine origin, we are told, seriously considering going underground to escape the consequences of his own folly. With a little wisdom and foresight, surely it is not yet necessary to forsake life in the fresh air and in the warmth of sunlight. What a paradox if our own cleverness in science should force us to live underground with the moles.