[Describing the effects of over-indulgence in wine:]
But most too passive, when the blood runs low
Too weakly indolent to strive with pain,
And bravely by resisting conquer fate,
Try Circe's arts; and in the tempting bowl
Of poisoned nectar sweet oblivion swill.
Struck by the powerful charm, the gloom dissolves
In empty air; Elysium opens round,
A pleasing frenzy buoys the lightened soul,
And sanguine hopes dispel your fleeting care;
And what was difficult, and what was dire,
Yields to your prowess and superior stars:
The happiest you of all that e'er were mad,
Or are, or shall be, could this folly last.
But soon your heaven is gone: a heavier gloom
Shuts o'er your head; and, as the thundering stream,
Swollen o'er its banks with sudden mountain rain,
Sinks from its tumult to a silent brook,
So, when the frantic raptures in your breast
Subside, you languish into mortal man;
You sleep, and waking find yourself undone,
For, prodigal of life, in one rash night
You lavished more than might support three days.
A heavy morning comes; your cares return
With tenfold rage. An anxious stomach well
May be endured; so may the throbbing head;
But such a dim delirium, such a dream,
Involves you; such a dastardly despair
Unmans your soul, as maddening Pentheus felt,
When, baited round Citheron's cruel sides,
He saw two suns, and double Thebes ascend.

Lost in a gloom of uninspired research.

Not all is doom and gloom. We are beginning to understand the natural world and are gaining a reverence for life - all life.

Only science, exact science about human nature itself, and the most sincere approach to it by the aid of the omnipotent scientific method, will deliver man from his present gloom and will purge him from his contemporary share in the sphere of interhuman relations.

The days of my youth extend backward to the dark ages, for I was born when the rush-light, the tallow-dip or the solitary blaze of the hearth were common means of indoor lighting, and an infrequent glass bowl, raised 8 or 10 feet on a wooden post, and containing a cup full of evil-smelling train-oil with a crude cotton wick stuck in it, served to make the darkness visible out of doors. In the chambers of the great, the wax candle or, exceptionally, a multiplicity of them, relieved the gloom on state occasions, but as a rule, the common people, wanting the inducement of indoor brightness such as we enjoy, went to bed soon after sunset.

The fear of meeting the opposition of envy, or the illiberality of ignorance is, no doubt, the frequent cause of preventing many ingenious men from ushering opinions into the world which deviate from common practice. Hence for want of energy, the young idea is shackled with timidity and a useful thought is buried in the impenetrable gloom of eternal oblivion.

The mere man of pleasure is miserable in old age, and the mere drudge in business is but little better, whereas, natural philosophy, mathematical and mechanical science, are a continual source of tranquil pleasure, and in spite of the gloomy dogmas of priests and of superstition, the study of these things is the true theology; it teaches man to know and admire the Creator, for the principles of science are in the creation, and are unchangeable and of divine origin.

The observer new to the scene would perhaps be first struck by the varied yet symmetrical trunks, which rise up with perfect straightness to a great height without a branch, and which, being placed at a considerable average distance apart, gives an impression similar to that produced by the columns of some enormous building. Overhead, at a height, perhaps, of a hundred feet, is an almost broken canopy of foliage formed by the meeting together of these great trees and their interlacing branches; and this canopy is usually so dense that but an indistinct glimmer of the sky is to be seen, and even the intense tropical sunlight only penetrates to the ground subdued and broken up into scattered fragments. There is a weird gloom and a solemn silence, which combine to produce a sense of the vast—the primeval—almost of the infinite. It is a world in which man seems an intruder.

The world is a museum in which all men are destined to be employed and amused, and they cannot be too much interested in the objects around them. Goldsmith the elegant imitator of Buffon, says “The mere uninformed spectator passes on in gloomy solitude; while the naturalist in every plant, in every insect, and in every pebble, finds something to entertain his curiosity and excite his speculation.”

When you enter some grove, peopled with ancient trees, such as are higher than ordinary, and whose boughs are so closely interwoven that you cannot see the sky; the stately loftiness of the wood, the privacy of the place, and the awful gloom, cannot but strike you, as with the presence of a deity.

Young men, trust those certain and powerful methods, only the first secrets of which we yet know. And all of you, whatever your career, … do not allow yourselves to be discouraged by the gloom of certain hours which pass a nation.