… the truth is that the knowledge of external nature and of the sciences which that knowledge requires or includes, is not the great or the frequent business of the human mind. Whether we provide for action or conversation, whether we wish to be useful or pleasing, the first requisite is the religious and moral knowledge of right and wrong; the next is an acquaintance with the history of mankind, and with those examples which may be said to embody truth, and prove by events the reasonableness of opinions. Prudence and justice are virtues, and excellencies, of all times and of all places; we are perpetually moralists, but we are geometricians only by chance. Our intercourse with intellectual nature is necessary; our speculations upon matter are voluntary, and at leisure. Physical knowledge is of such rare emergence, that one man may know another half his life without being able to estimate his skill in hydrostatics or astronomy; but his moral and prudential character immediately appears.

[1665-12-31] Thus ends this year ... It is true we have gone through great melancholy because of the great plague, and I put to great charges by it, by keeping my family long at Woolwich, and myself and another part of my family, my clerks, at my charge at Greenwich ... But now the plague is abated almost to nothing ... But many of such as I know very well, dead. Yet to our great joy, the town fills apace, and shops begin to open again. Pray God continue the plague's decrease - for that keeps the Court away from the place of business, and so all goes to wrack as to public matters, they at this distance not thinking of it.

[About the structure of DNA] [T]he whole business was like a child's toy that you could buy at the dime store, all built in this wonderful way that you could explain in Life magazine so that really a five-year-old can understand what's going on...This was the greatest surprise for everyone.

[Alfred Russell] Wallace's sales agent, back in London, heard mutterings from some naturalists that young Mr. Wallace ought to quit theorizing and stick to gathering facts. Besides expressing their condescension toward him in particular, that criticism also reflected a common attitude that fact-gathering, not theory, was the proper business of all naturalists.

[Florence Nightingale] was a great administrator, and to reach excellence here is impossible without being an ardent student of statistics. Florence Nightingale has been rightly termed the “Passionate Statistician.” Her statistics were more than a study, they were indeed her religion. For her, Quetelet was the hero as scientist, and the presentation copy of his Physique Sociale is annotated by her on every page. Florence Nightingale believed—and in all the actions of her life acted upon that belief—that the administrator could only be successful if he were guided by statistical knowledge. The legislator—to say nothing of the politician—too often failed for want of this knowledge. Nay, she went further: she held that the universe—including human communities—was evolving in accordance with a divine plan; that it was man's business to endeavour to understand this plan and guide his actions in sympathy with it. But to understand God's thoughts, she held we must study statistics, for these are the measure of his purpose. Thus the study of statistics was for her a religious duty.

[In relation to business:] Invention must be its keynote—a steady progression from one thing to another. As each in turn approaches a saturated market, something new must be produced.

[May] this civic and social landmark [the Washington, D.C., Jewish Community Center] ... be a constant reminder of the inspiring service that has been rendered to civilization by men and women of the Jewish faith. May [visitors] recall the long array of those who have been eminent in statecraft, in science, in literature, in art, in the professions, in business, in finance, in philanthropy and in the spiritual life of the world.

[Regarding evolution believers:] Their business is not with the possible, but the actual—not with a world which might be, but with a world that is. This they explore with a courage not unmixed with reverence, and according to methods which, like the quality of a tree, are tested by their fruits. They have but one desire—to know the truth. They have but one fear—to believe a lie.

[The best motivator for employees is] progress.

[The biggest myth in business is that] bigger is better. A business should be judged not by its size but its impact.

[The toughest part of being in charge is] killing ideas that are great but poorly timed. And delivering tough feedback that’s difficult to hear but that I know will help people—and the team—in the long term.

Combination does not produce though mergers and combinations are still the accepted panacea. In Big business there appears to be increasing aridity, bureaucracy, and stultifying sacrifice of initiative and above all fear.

Die Natur hates sich nicht angelegen sein lassen, uns die Auffindung ihrer Gesetze bequem zu machen.
Nature did not deem it her business to make the discovery of her laws easy for us.

In primis, hominis est propria VERI inquisitio atque investigato. Itaque cum sumus negotiis necessariis, curisque vacui, tum avemus aliquid videre, audire, ac dicere, cognitionemque rerum, aut occultarum aut admirabilium, ad benè beatéque vivendum necessariam ducimus; —ex quo intelligitur, quod VERUM, simplex, sincerumque sit, id esse naturæ hominis aptissimum. Huic veri videndi cupiditati adjuncta est appetitio quædam principatûs, ut nemini parere animus benè a naturâ informatus velit, nisi præcipienti, aut docenti, aut utilitatis causâ justè et legitimè imperanti: ex quo animi magnitudo existit, et humanarum rerum contemtio.
Before all other things, man is distinguished by his pursuit and investigation of TRUTH. And hence, when free from needful business and cares, we delight to see, to hear, and to communicate, and consider a knowledge of many admirable and abstruse things necessary to the good conduct and happiness of our lives: whence it is clear that whatsoever is TRUE, simple, and direct, the same is most congenial to our nature as men. Closely allied with this earnest longing to see and know the truth, is a kind of dignified and princely sentiment which forbids a mind, naturally well constituted, to submit its faculties to any but those who announce it in precept or in doctrine, or to yield obedience to any orders but such as are at once just, lawful, and founded on utility. From this source spring greatness of mind and contempt of worldly advantages and troubles.

A fossil hunter needs sharp eyes and a keen search image, a mental template that subconsciously evaluates everything he sees in his search for telltale clues. A kind of mental radar works even if he isn’t concentrating hard. A fossil mollusk expert has a mollusk search image. A fossil antelope expert has an antelope search image. … Yet even when one has a good internal radar, the search is incredibly more difficult than it sounds. Not only are fossils often the same color as the rocks among which they are found, so they blend in with the background; they are also usually broken into odd-shaped fragments. … In our business, we don’t expect to find a whole skull lying on the surface staring up at us. The typical find is a small piece of petrified bone. The fossil hunter’s search therefore has to have an infinite number of dimensions, matching every conceivable angle of every shape of fragment of every bone on the human body.
Describing the skill of his co-worker, Kamoya Kimeu, who discovered the Turkana Boy, the most complete specimen of Homo erectus, on a slope covered with black lava pebbles.

A man is likely to mind his own business when it is worth minding. When it is not, he takes his mind off his own meaningless affairs by minding other people’s business.

A man may be born a jackass; but it is his business if he makes himself a double one.

A propos of Distempers, I am going to tell you a thing that I am sure will make you wish your selfe here. The Small Pox so fatal and so general amongst us is here entirely harmless by the invention of engrafting (which is the term they give it). There is a set of old Women who make it their business to perform the Operation.

A system such as classical mechanics may be ‘scientific’ to any degree you like; but those who uphold it dogmatically — believing, perhaps, that it is their business to defend such a successful system against criticism as long as it is not conclusively disproved — are adopting the very reverse of that critical attitude which in my view is the proper one for the scientist.

A work of genius is something like the pie in the nursery song, in which the four and twenty blackbirds are baked. When the pie is opened, the birds begin to sing. Hereupon three fourths of the company run away in a fright; and then after a time, feeling ashamed, they would fain excuse themselves by declaring, the pie stank so, they could not sit near it. Those who stay behind, the men of taste and epicures, say one to another, We came here to eat. What business have birds, after they have been baked, to be alive and singing? This will never do. We must put a stop to so dangerous an innovation: for who will send a pie to an oven, if the birds come to life there? We must stand up to defend the rights of all the ovens in England. Let us have dead birds..dead birds for our money. So each sticks his fork into a bird, and hacks and mangles it a while, and then holds it up and cries, Who will dare assert that there is any music in this bird’s song?

Accountants and second-rate business school jargon are in the ascendant. Costs, which rise rapidly, and are easily ascertained and comprehensible, now weigh more heavily in the scales than the unquantifiable and unpredictable values and future material progress. Perhaps science will only regain its lost primacy as peoples and government begin to recognize that sound scientific work is the only secure basis for the construction of policies to ensure the survival of Mankind without irreversible damage to Planet Earth.

Adam is fading out. It is on account of Darwin and that crowd. I can see that he is not going to last much longer. There's a plenty of signs. He is getting belittled to a germ—a little bit of a speck that you can't see without a microscope powerful enough to raise a gnat to the size of a church. They take that speck and breed from it: first a flea; then a fly, then a bug, then cross these and get a fish, then a raft of fishes, all kinds, then cross the whole lot and get a reptile, then work up the reptiles till you've got a supply of lizards and spiders and toads and alligators and Congressmen and so on, then cross the entire lot again and get a plant of amphibiums, which are half-breeds and do business both wet and dry, such as turtles and frogs and ornithorhyncuses and so on, and cross-up again and get a mongrel bird, sired by a snake and dam'd by a bat, resulting in a pterodactyl, then they develop him, and water his stock till they've got the air filled with a million things that wear feathers, then they cross-up all the accumulated animal life to date and fetch out a mammal, and start-in diluting again till there's cows and tigers and rats and elephants and monkeys and everything you want down to the Missing Link, and out of him and a mermaid they propagate Man, and there you are! Everything ship-shape and finished-up, and nothing to do but lay low and wait and see if it was worth the time and expense.

After you have exhausted what there is in business, politics, conviviality, and so on - have found that none of these finally satisfy, or permanently wear - what remains? Nature remains.

And for rejecting such a Medium, we have the Authority of those the oldest and most celebrated Philosophers of Greece and Phoenicia, who made a Vacuum, and Atoms, and the Gravity of Atoms, the first Principles of their Philosophy; tacitly attributing Gravity to some other Cause than dense Matter. Later Philosophers banish the Consideration of such a Cause out of natural Philosophy, feigning Hypotheses for explaining all things mechanically, and referring other Causes to Metaphysicks: Whereas the main Business of natural Philosophy is to argue from Phaenomena without feigning Hypotheses, and to deduce Causes from Effects, till we come to the very first Cause, which certainly is not mechanical; and not only to unfold the Mechanism of the World, but chiefly to resolve these and such like Questions. What is there in places almost empty of Matter, and whence is it that the Sun and Planets gravitate towards one another, without dense Matter between them? Whence is it that Nature doth nothing in vain; and whence arises all that Order and Beauty which we see in the World? ... does it not appear from phaenomena that there is a Being incorporeal, living, intelligent, omnipresent, who in infinite space, as it were in his Sensory, sees the things themselves intimately, and thoroughly perceives them, and comprehends them wholly by their immediate presence to himself.

Art is the beautiful way of doing things. Science is the effective way of doing things. Business is the economic way of doing things.

As a career, the business of an orthodox preacher is about as successful as that of a celluloid dog chasing an asbestos cat through hell.

As to how far in advance of the first flight the man should know he’s going. I’m not in agreement with the argument that says word should be delayed until the last possible moment to save the pilot from developing a bad case of the jitters. If we don’t have the confidence to keep from getting clutched at that time, we have no business going at all. If I’m the guy going, I’ll be glad to get the dope as soon as possible. As for keeping this a big secret from us and having us all suited up and then saying to one man “you go” and stuffing him in and putting the lid on that thing and away he goes, well, we’re all big boys now.

Ask a follower of Bacon what [science] the new philosophy, as it was called in the time of Charles the Second, has effected for mankind, and his answer is ready; “It has lengthened life; it has mitigated pain; it has extinguished diseases; it has increased the fertility of the soil; it has given new securities to the mariner; it has furnished new arms to the warrior; it has spanned great rivers and estuaries with bridges of form unknown to our fathers; it has guided the thunderbolt innocuously from heaven to earth; it has lighted up the night with the splendour of the day; it has extended the range of the human vision; it has multiplied the power of the human muscles; it has accelerated motion; it has annihilated distance; it has facilitated intercourse, correspondence, all friendly offices, all dispatch of business; it has enabled man to descend to the depths of the sea, to soar into the air, to penetrate securely into the noxious recesses of the earth, to traverse the land in cars which whirl along without horses, to cross the ocean in ships which run ten knots an hour against the wind. These are but a part of its fruits, and of its first-fruits; for it is a philosophy which never rests, which has never attained, which is never perfect. Its law is progress. A point which yesterday was invisible is its goal to-day, and will be its starting-point to-morrow.”

At first the squirrel spins his cage; then the cage spins him. Men of business may take warning.

Business is just about enabling human beings, nothing more, nothing less. Businesses need to recognize this fundamental fact.

Business men are to be pitied who do not recognize the fact that the largest side of their secular business is benevolence. ... No man ever manages a legitimate business in this life without doing indirectly far more for other men than he is trying to do for himself.

Business should be like religion and science; it should know neither love nor hate.

Business, to be successful, must be based on science, for demand and supply are matters of mathematics, not guesswork.

But how is one to determine what is pleasing to God? ... Whatever is unpleasant to man is pleasant to God. The test is the natural instinct of man. If there arises within one’s dark recesses a hot desire to do this or that, then it is the paramount duty of a Christian to avoid doing this or that. And if, on the contrary, one cherishes an abhorrence of the business, then one must tackle it forthwith, all the time shouting ‘Hallelujah!’ A simple enough religion, surely–simple, satisfying and idiotic.

But the idea of science and systematic knowledge is wanting to our whole instruction alike, and not only to that of our business class ... In nothing do England and the Continent at the present moment more strikingly differ than in the prominence which is now given to the idea of science there, and the neglect in which this idea still lies here; a neglect so great that we hardly even know the use of the word science in its strict sense, and only employ it in a secondary and incorrect sense.

Dressed very plainly, usually with a plain brown skirt of tweed. No cosmetics. Neat but not ostentatious. After all, business was business. She [Florence Sabin] would lecture twice a week. Very rapidly spoken, a little muddy—she was so enthusiastic in trying to correlate the scientific and medical aspect of anatomy (histology). She would tear up her notes after each lecture so that she would have to work it over the next year.

During my pre-college years I went on many trips with my father into the oil fields to visit their operations. … I puttered around the machine, electronics, and automobile shops while he carried on his business. Both of my parents are inveterate do-it-yourselfers, almost no task being beneath their dignity or beyond their ingenuity. Having picked up a keen interest in electronics from my father, I used to fix radios and later television sets for fun and spending money. I built my own hi-fi set and enjoyed helping friends with their amateur radio transmitters, but lost interest as soon as they worked.

Each volcano is an independent machine—nay, each vent and monticule is for the time being engaged in its own peculiar business, cooking as it were its special dish, which in due time is to be separately served. We have instances of vents within hailing distance of each other pouring out totally different kinds of lava, neither sympathizing with the other in any discernible manner nor influencing other in any appreciable degree.

Early diagnosis of disease is the business of the general public even more than of the medical profession.

ENGINEER, in the military art, an able expert man, who, by a perfect knowledge in mathematics, delineates upon paper, or marks upon the ground, all sorts of forts, and other works proper for offence and defence. He should understand the art of fortification, so as to be able, not only to discover the defects of a place, but to find a remedy proper for them; as also how to make an attack upon, as well as to defend, the place. Engineers are extremely necessary for these purposes: wherefore it is requisite that, besides being ingenious, they should be brave in proportion. When at a siege the engineers have narrowly surveyed the place, they are to make their report to the general, by acquainting him which part they judge the weakest, and where approaches may be made with most success. Their business is also to delineate the lines of circumvallation and contravallation, taking all the advantages of the ground; to mark out the trenches, places of arms, batteries, and lodgments, taking care that none of their works be flanked or discovered from the place. After making a faithful report to the general of what is a-doing, the engineers are to demand a sufficient number of workmen and utensils, and whatever else is necessary.

Engineering is the science of economy, of conserving the energy, kinetic and potential, provided and stored up by nature for the use of man. It is the business of engineering to utilize this energy to the best advantage, so that there may be the least possible waste.

Engineering, medicine, business, architecture and painting are concerned not with the necessary but with the contingent—not with how things are but with how they might be—in short, with design.

Enthusiasm for the global-warming scare also ensures that heatwaves make headlines, while contrary symptoms, such as this winter’s billion-dollar loss of Californian crops to unusual frost, are relegated to the business pages. The early arrival of migrant birds in spring provides colourful evidence for a recent warming of the northern lands. But did anyone tell you that in east Antarctica the Adélie penguins and Cape petrels are turning up at their spring nesting sites around nine days later than they did 50 years ago? While sea-ice has diminished in the Arctic since 1978, it has grown by 8% in the Southern Ocean.

Environmentalism opposes reckless innovation and makes conservation the central order of business.

For the evolution of science by societies the main requisite is the perfect freedom of communication between each member and anyone of the others who may act as a reagent.
The gaseous condition is exemplified in the soiree, where the members rush about confusedly, and the only communication is during a collision, which in some instances may be prolonged by button-holing.
The opposite condition, the crystalline, is shown in the lecture, where the members sit in rows, while science flows in an uninterrupted stream from a source which we take as the origin. This is radiation of science. Conduction takes place along the series of members seated round a dinner table, and fixed there for several hours, with flowers in the middle to prevent any cross currents.
The condition most favourable to life is an intermediate plastic or colloidal condition, where the order of business is (1) Greetings and confused talk; (2) A short communication from one who has something to say and to show; (3) Remarks on the communication addressed to the Chair, introducing matters irrelevant to the communication but interesting to the members; (4) This lets each member see who is interested in his special hobby, and who is likely to help him; and leads to (5) Confused conversation and examination of objects on the table.
I have not indicated how this programme is to be combined with eating.

Get rid of every pound of material you can do without; put to yourself the question, ‘What business has this to be there?’

God bless all the precious little examples and all their cascading implications; without these gems, these tiny acorns bearing the blueprints of oak trees, essayists would be out of business.

He, who for an ordinary cause, resigns the fate of his patient to mercury, is a vile enemy to the sick; and, if he is tolerably popular, will, in one successful season, have paved the way for the business of life, for he has enough to do, ever afterward, to stop the mercurial breach of the constitutions of his dilapidated patients. He has thrown himself in fearful proximity to death, and has now to fight him at arm's length as long as the patient maintains a miserable existence.

His [Edison’s] greatest invention was that of the industrial research laboratory, turning out inventions as a business.

I am a woman who came from the cotton fields of the South. From there I was promoted to the washtub. From there I was promoted to the cook kitchen. And from there I promoted myself into the business of manufacturing hair goods and preparations….I have built my own factory on my own ground.

I am more of a sponge than an inventor. I absorb ideas from every source. I take half-matured schemes for mechanical development and make them practical. I am a sort of middleman between the long-haired and impractical inventor and the hard-headed businessman who measures all things in terms of dollars and cents. My principal business is giving commercial value to the brilliant but misdirected ideas of others.

I find that by confining a workman to one particular limb of the pistol until he has made two thousand, I save at least one quarter of his labor, to what I should provided I finishd them by small quantities; and the work will be as much better as it is quicker made. ... I have some seventeen thousand screws & other parts of pistols now forgd. & many parts nearly finished & the business is going on brisk and lively.
Describing subdivision of labour and standardization of parts.

I have a true aversion to teaching. The perennial business of a professor of mathematics is only to teach the ABC of his science; most of the few pupils who go a step further, and usually to keep the metaphor, remain in the process of gathering information, become only Halbwisser [one who has superficial knowledge of the subject], for the rarer talents do not want to have themselves educated by lecture courses, but train themselves. And with this thankless work the professor loses his precious time.

I have always liked horticulturists, people who make their living from orchards and gardens, whose hands are familiar with the feel of the bark, whose eyes are trained to distinguish the different varieties, who have a form memory. Their brains are not forever dealing with vague abstractions; they are satisfied with the romance which the seasons bring with them, and have the patience and fortitude to gamble their lives and fortunes in an industry which requires infinite patience, which raise hopes each spring and too often dashes them to pieces in fall. They are always conscious of sun and wind and rain; must always be alert lest they lose the chance of ploughing at the right moment, pruning at the right time, circumventing the attacks of insects and fungus diseases by quick decision and prompt action. They are manufacturers of a high order, whose business requires not only intelligence of a practical character, but necessitates an instinct for industry which is different from that required by the city dweller always within sight of other people and the sound of their voices. The successful horticulturist spends much time alone among his trees, away from the constant chatter of human beings.

I think, considering what they have had to fight against, that women have been wonderful. I see no end to their development in science, as in the arts and professions and in business, if they have the will to work.

I would have my son mind and understand business, read little history, study the mathematics and cosmography; these are good, with subordination to the things of God. … These fit for public services for which man is born.

I’m afraid for all those who’ll have the bread snatched from their mouths by these machines. … What business has science and capitalism got, bringing ail these new inventions into the works, before society has produced a generation educated up to using them!

If [science] tends to thicken the crust of ice on which, as it were, we are skating, it is all right. If it tries to find, or professes to have found, the solid ground at the bottom of the water it is all wrong. Our business is with the thickening of this crust by extending our knowledge downward from above, as ice gets thicker while the frost lasts; we should not try to freeze upwards from the bottom.

If Thomas Edison had gone to business school, we would all be reading by larger candles.

If we die, we want people to accept it. We’re in a risky business, and we hope that if anything happens to us it will not delay the program. The conquest of space is worth the risk of life.

If you defend a behavior by arguing that people are programmed directly for it, then how do you continue to defend it if your speculation is wrong, for the behavior then becomes unnatural and worthy of condemnation. Better to stick resolutely to a philosophical position on human liberty: what free adults do with each other in their own private lives is their business alone. It need not be vindicated–and must not be condemned–by genetic speculation.

If you do not feel equal to the headaches that psychiatry induces, you are in the wrong business. It is work - work the like of which I do not know.

Improvements in industry can be left to chance in the hope that someone, sometime, will think of something useful. that some good invention will show up. The other way is to organize so that new knowledge shall always be coming from the researches in the fundamental sciences and engineering arts on which business is based. From that steady stream will arise inventions and new methods. This is the way of Bell Laboratories.

In every phase of business life, keep at least one year ahead of the other fellow.

Is it not evident, in these last hundred years (when the Study of Philosophy has been the business of all the Virtuosi in Christendome) that almost a new Nature has been revealed to us? that more errours of the School have been detected, more useful Experiments in Philosophy have been made, more Noble Secrets in Opticks, Medicine, Anatomy, Astronomy, discover'd, than in all those credulous and doting Ages from Aristotle to us? So true it is that nothing spreads more fast than Science, when rightly and generally cultivated.

It is a wrong business when the younger cultivators of science put out of sight and deprecate what their predecessors have done; but obviously that is the tendency of Huxley and his friends … It is very true that Huxley was bitter against the Bishop of Oxford, but I was not present at the debate. Perhaps the Bishop was not prudent to venture into a field where no eloquence can supersede the need for precise knowledge. The young naturalists declared themselves in favour of Darwin’s views which tendency I saw already at Leeds two years ago. I am sorry for it, for I reckon Darwin’s book to be an utterly unphilosophical one.

It is no part of a physician's business to use either persuasion or compulsion upon the patients.

It is not the business of science to inherit the earth, but to inherit the moral imagination; because without that, man and beliefs and science will perish together.

It is not therefore the business of philosophy, in our present situation in the universe, to attempt to take in at once, in one view, the whole scheme of nature; but to extend, with great care and circumspection, our knowledge, by just steps, from sensible things, as far as our observations or reasonings from them will carry us, in our enquiries concerning either the greater motions and operations of nature, or her more subtile and hidden works. In this way Sir Isaac Newton proceeded in his discoveries.

It is the business of science to offer rational explanations for all the events in the real world, and any scientist who calls on God to explain something is falling down on his job. This applies as much to the start of the expansion as to any other event. If the explanation is not forthcoming at once, the scientist must suspend judgment: but if he is worth his salt he will always maintain that a rational explanation will eventually be found. This is the one piece of dogmatism that a scientist can allow himself—and without it science would be in danger of giving way to superstition every time that a problem defied solution for a few years.

It is the business of scientists to explain away the magic in the world. The largest coherent body of magic remaining is the behavior of (humans) and animals.

It is the business of the future to be dangerous; and it is among the merits of science that it equips the future for its duties.

It may not always be profitable at first for businesses to be online, but it is certainly going to be unprofitable not to be online.

It often happens that men, even of the best understandings and greatest circumspection, are guilty of that fault in reasoning which the writers on logick call the insufficient, or imperfect enumeration of parts, or cases: insomuch that I will venture to assert, that this is the chief, and almost the only, source of the vast number of erroneous opinions, and those too very often in matters of great importance, which we are apt to form on all the subjects we reflect upon, whether they relate to the knowledge of nature, or the merits and motives of human actions. It must therefore be acknowledged, that the art which affords a cure to this weakness, or defect, of our understandings, and teaches us to enumerate all the possible ways in which a given number of things may be mixed and combined together, that we may be certain that we have not omitted anyone arrangement of them that can lead to the object of our inquiry, deserves to be considered as most eminently useful and worthy of our highest esteem and attention. And this is the business of the art, or doctrine of combinations ... It proceeds indeed upon mathematical principles in calculating the number of the combinations of the things proposed: but by the conclusions that are obtained by it, the sagacity of the natural philosopher, the exactness of the historian, the skill and judgement of the physician, and the prudence and foresight of the politician, may be assisted; because the business of all these important professions is but to form reasonable conjectures concerning the several objects which engage their attention, and all wise conjectures are the results of a just and careful examination of the several different effects that may possibly arise from the causes that are capable of producing them.

It was to Hofmeister, working as a young man, an amateur and enthusiast, in the early morning hours of summer months, before business, at Leipzig in the years before 1851, that the vision first appeared of a common type of Life-Cycle, running through Mosses and Ferns to Gymnosperms and Flowering Plants, linking the whole series in one scheme of reproduction and life-history.

Life and business are rather simple after all—to make a success of either, you've got to hang on to the knack of putting yourself into the other person's place.

Many orthodox people speak as though it were the business of sceptics to disprove received dogmas rather than of dogmatists to prove them. This is, of course, a mistake.

Medicine is a noble profession but a damn bad business.

Mother: He’s been depressed. All of a sudden, he can’t do anything.
Doctor: Why are you depressed, Alvy?
Mother: Tell Dr. Flicker. It’s something he read.
Doctor: Something he read, huh?
Alvy: The universe is expanding.
Doctor: The universe is expanding?
Alvy: Well, the universe is everything, and if it’s expanding, someday it will break apart and that would be the end of everything!
Mother: What is that your business? He stopped doing his homework.
Alvy: What’s the point?

My decision to leave applied mathematics for economics was in part tied to the widely-held popular belief in the 1960s that macroeconomics had made fundamental inroads into controlling business cycles and stopping dysfunctional unemployment and inflation.

Nature! … She tosses her creatures out of nothingness, and tells them not whence they came, nor whither they go. It is their business to run, she knows the road.

No nation can be really great unless it is great in peace, in industry, integrity, honesty. Skilled intelligence in civic affairs and industrial enterprises alike; the special ability of the artist, the man of letters, the man of science, and the man of business; the rigid determination to wrong no man, and to stand for righteousness—all these are necessary in a great nation.

No scientist is admired for failing in the attempt to solve problems that lie beyond his competence. … Good scientists study the most important problems they think they can solve. It is, after all, their professional business to solve problems, not merely to grapple with them.

Now, the causes being four, it is the business of the student of nature to know about them all, and if he refers his problems back to all of them, he will assign the “why” in the way proper to his science—the matter, the form, the mover, that for the sake of which.

Our progress in education has truly been a curious one. We have gone from the hard and arbitrary curriculum, with its primary insistence upon training the memory and the consequent devitalization of valuable and beneficial subjects, to the free elective system, with its wholesale invitations to follow the paths of least resistance, back to a half-hearted compromise somewhere between the two extremes, and we have arrived at what? Certainly at little more than an educational jumble. A maelstrom in which the maximum amount of theory and the minimum amount of practice whirl those who are thrown into it round and round for definitely fixed periods of time, to be cast out as flotsam for another period until corporate business and industrial organizations can accomplish that which could and should have been done by general education.

Parkinson's Law is a purely scientific discovery, inapplicable except in theory to the politics of the day. It is not the business of the botanist to eradicate the weeds. Enough for him if he can tell us just how fast they grow.

People without independence have no business to meddle with science. It should never be linked with lucre.

Reality is the real business of physics.

Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.

Research has been called good business, a necessity, a gamble, a game. It is none of these—it’s a state of mind.

Science is a capital or fund perpetually reinvested; it accumulates, rolls up, is carried forward by every new man. Every man of science has all the science before him to go upon, to set himself up in business with. What an enormous sum Darwin availed himself of and reinvested! Not so in literature; to every poet, to every artist, it is still the first day of creation, so far as the essentials of his task are concerned. Literature is not so much a fund to be reinvested as it is a crop to be ever new-grown.

Science is really in the business of disproving current models or changing them to conform to new information. In essence, we are constantly proving our latest ideas wrong.

Shall an invention be patented or donated to the public freely? I have known some well-meaning scientific men to look askance at the patenting of inventions, as if it were a rather selfish and ungracious act, essentially unworthy. The answer is very simple. Publish an invention freely, and it will almost surely die from lack of interest in its development. It will not be developed and the world will not be benefited. Patent it, and if valuable, it will be taken up and developed into a business.

Some day when you have time, look into the business of prayer, amulets, baths, and poultices, and discover much valuable therapy the profession has cast on the dump

Success is being able to make an impact in what matters most to you.

Suppose the results of a line of study are negative. It might save a lot of otherwise wasted money to know a thing won’t work. But how do you accurately evaluate negative results? ... The power plant in [the recently developed streamline trains] is a Diesel engine of a type which was tried out many [around 25] years ago and found to be a failure. … We didn’t know how to build them. The principle upon which it operated was sound. [Since then much has been] learned in metallurgy [and] the accuracy with which parts can be manufactured
When this type of engine was given another chance it was an immediate success [because now] an accuracy of a quarter of a tenth of a thousandth of an inch [prevents high-pressure oil leaks]. … If we had taken the results of past experience without questioning the reason for the first failure, we would never have had the present light-weight, high-speed Diesel engine which appears to be the spark that will revitalize the railroad business.

Thanks to the freedom of our press and the electronic media, the voices of cranks are often louder and clearer than the voices of genuine scientists. Crank books—on how to lose weight without cutting down on calories, on how to talk to plants, on how to cure your ailments by rubbing your feet, on how to apply horoscopes to your pets, on how to use ESP in making business decisions, on how to sharpen razor blades by putting them under little models of the great Pyramid of Egypt—far outsell many books… I reserve the right of moral indignation.

The beautiful has its place in mathematics as elsewhere. The prose of ordinary intercourse and of business correspondence might be held to be the most practical use to which language is put, but we should be poor indeed without the literature of imagination. Mathematics too has its triumphs of the Creative imagination, its beautiful theorems, its proofs and processes whose perfection of form has made them classic. He must be a “practical” man who can see no poetry in mathematics.

The best class of scientific mind is the same as the best class of business mind. The great desideratum in either case is to know how much evidence is enough to warrant action. It is as unbusiness-like to want too much evidence before buying or selling as to be content with too little. The same kind of qualities are wanted in either case. The difference is that if the business man makes a mistake, he commonly has to suffer for it, whereas it is rarely that scientific blundering, so long as it is confined to theory, entails loss on the blunderer. On the contrary it very often brings him fame, money and a pension. Hence the business man, if he is a good one, will take greater care not to overdo or underdo things than the scientific man can reasonably be expected to take.

The business of concrete mathematics is to discover the equations which express the mathematical laws of the phenomenon under consideration; and these equations are the starting-point of the calculus, which must obtain from them certain quantities by means of others.

The business of their weekly Meetings shall be, To order, take account, consider, and discourse of Philosophical Experiments, and Observations: to read, hear, and discourse upon Letters, Reports, and other Papers containing Philosophical matters, as also to view, and discourse upon the productions and rarities of Nature, and Art: and to consider what to deduce from them, or how they may be improv'd for use, or discovery.

The Chinese … use fossil teeth as one of their principal medicines. Some Chinese families have for centuries been in the business of “mining” fossils to supply the drug trade.

The close observation of little things is the secret of success in business, in art, in science, and in every pursuit in life.

The contents of this section will furnish a very striking illustration of the truth of a remark, which I have more than once made in my philosophical writings, and which can hardly be too often repeated, as it tends greatly to encourage philosophical investigations viz. That more is owing to what we call chance, that is, philosophically speaking, to the observation of events arising from unknown causes, than to any proper design, or pre-conceived theory in this business. This does not appear in the works of those who write synthetically upon these subjects; but would, I doubt not, appear very strikingly in those who are the most celebrated for their philosophical acumen, did they write analytically and ingenuously.

The critical mathematician has abandoned the search for truth. He no longer flatters himself that his propositions are or can be known to him or to any other human being to be true; and he contents himself with aiming at the correct, or the consistent. The distinction is not annulled nor even blurred by the reflection that consistency contains immanently a kind of truth. He is not absolutely certain, but he believes profoundly that it is possible to find various sets of a few propositions each such that the propositions of each set are compatible, that the propositions of each such set imply other propositions, and that the latter can be deduced from the former with certainty. That is to say, he believes that there are systems of coherent or consistent propositions, and he regards it his business to discover such systems. Any such system is a branch of mathematics.

The difference between a successful and an unsuccessful business man lies often in the greater accuracy of the former’s guesses. Statistics are no substitution for judgment. Their use is to check and discipline the judgments on which in the last resort business decisions depend.

The Earth has no business possessing such a Moon. It is too huge—over a quarter Earth’s diameter and about 1/81 of its mass. No other planet in the Solar System has even nearly so large a satellite.

The education of the intellect is a great business, but an unconsecrated intellect is a sight than which the sun in all his daily course can see no sadder.

The fact is that up to now the free society has not been good for the intellectual. It has neither accorded him a superior status to sustain his confidence nor made it easy for him to acquire an unquestioned sense of social usefulness. For he derives his sense of usefulness mainly from directing, instructing, and planning-from minding other people’s business-and is bound to feel superfluous and neglected where people believe themselves competent to manage individual and communal affairs, and are impatient of supervision and regulation. A free society is as much a threat to the intellectual’s sense of worth as an automated economy is to the workingman’s sense of worth. Any social order that can function with a minimum of leadership will be anathema to the intellectual.

The first business of a man of science is to proclaim the truth as he finds it, and let the world adjust itself as best it can to the new knowledge.

The first business of a teacher … should be to excite … curiosity. … This process saves a student from being (as many are) intellectually damaged by having a very good memory.

The God whom science recognizes must be a God of universal laws exclusively, a God who does a wholesale, not a retail business. He cannot accommodate his processes to the convenience of individuals.

The great companies did not know that the line between hunger and anger is a thin line. And money that might have gone to wages went for gas, for guns, for agents and spies, for blacklists, for drilling. On the highways the people moved like ants and searched for work, for food. And the anger began to ferment.

The growth of a large business is merely a survival of the fittest. … The American Beauty rose can be produced in the splendor and fragrance which bring cheer to its beholder only by sacrificing the early buds which grow up around it. This is not an evil tendency in business. It is merely the working-out of a law of nature and a law of God.

The hype, skepticism and bewilderment associated with the Internet—concerns about new forms of crime, adjustments in social mores, and redefinition of business practices— mirror the hopes, fears, and misunderstandings inspired by the telegraph. Indeed, they are only to be expected. They are the direct consequences of human nature, rather than technology.
Given a new invention, there will always be some people who see only its potential to do good, while others see new opportunities to commit crime or make money. We can expect the same reactions to whatever new inventions appear in the twenty-first century.
Such reactions are amplified by what might be termed chronocentricity—the egotism that one’s own generation is poised on the very cusp of history. Today, we are repeatedly told that we are in the midst of a communications revolution. But the electric telegraph was, in many ways, far more disconcerting for the inhabitants of the time than today’s advances are for us. If any generation has the right to claim that it bore the full bewildering, world-shrinking brunt of such a revolution, it is not us—it is our nineteenth- century forebears.

The idea of a method that contains firm, unchanging, and absolutely binding principles for conducting the business of science meets considerable difficulty when confronted with the results of historical research. We find, then, that there is not a single rule, however plausible, and however firmly grounded in epistemology, that is not violated at some time or another.

The key to success for Sony, and to everything in business, science and technology for that matter, is never to follow the others.

The known is finite, the unknown infinite; intellectually we stand on an islet in the midst of an illimitable ocean of inexplicability. Our business in every generation is to reclaim a little more land, to add something to the extent and the solidity of our possessions. And even a cursory glance at the history of the biological sciences during the last quarter of a century is sufficient to justify the assertion, that the most potent instrument for the extension of the realm of natural knowledge which has come into men’s hands, since the publication of Newton's ‘Principia’, is Darwin's ‘Origin of Species.’

The large collection of problems which our modern Cambridge books supply will be found to be almost an exclusive peculiarity of these books; such collections scarcely exist in foreign treatises on mathematics, nor even in English treatises of an earlier date. This fact shows, I think, that a knowledge of mathematics may be gained without the perpetual working of examples. … Do not trouble yourselves with the examples, make it your main business, I might almost say your exclusive business, to understand the text of your author.

The long-range trend toward federal regulation, which found its beginnings in the Interstate Commerce Act of 1887 and the Sherman Act of 1890, which was quickened by a large number of measures in the Progressive era, and which has found its consummation in our time, was thus at first the response of a predominantly individualistic public to the uncontrolled and starkly original collectivism of big business. In America the growth of the national state and its regulative power has never been accepted with complacency by any large part of the middle-class public, which has not relaxed its suspicion of authority, and which even now gives repeated evidence of its intense dislike of statism. In our time this growth has been possible only under the stress of great national emergencies, domestic or military, and even then only in the face of continuous resistance from a substantial part of the public. In the Progressive era it was possible only because of widespread and urgent fear of business consolidation and private business authority. Since it has become common in recent years for ideologists of the extreme right to portray the growth of statism as the result of a sinister conspiracy of collectivists inspired by foreign ideologies, it is perhaps worth emphasizing that the first important steps toward the modern organization of society were taken by arch-individualists—the tycoons of the Gilded Age—and that the primitive beginning of modern statism was largely the work of men who were trying to save what they could of the eminently native Yankee values of individualism and enterprise.

The main Business of Natural Philosophy is to argue from Phænomena without feigning Hypotheses, and to deduce Causes from Effects till we come to the very first Cause, which certainly is not mechanical; and not only to unfold the Mechanism of the World, but chiefly to resolve these, and to such like Questions.

The maintenance of security … required every member of the project to attend strictly to his own business. The result was an operation whose efficiency was without precedent.

The mere man of pleasure is miserable in old age, and the mere drudge in business is but little better, whereas, natural philosophy, mathematical and mechanical science, are a continual source of tranquil pleasure, and in spite of the gloomy dogmas of priests and of superstition, the study of these things is the true theology; it teaches man to know and admire the Creator, for the principles of science are in the creation, and are unchangeable and of divine origin.

The more you’re in this business, the more conservative you get. I’ve been in it long enough to be very conservative, to want to improve what we’ve got rather than begin by building what we haven’t.

The personal views of the lecturer may seem to be brought forward with undue exclusiveness, but, as it is his business to give a clear exposition of the actual state of the science which he treats, he is obliged to define with precision the principles, the correctness of which he has proved by his own experience.

The point in which I am different from most inventors is that I have, besides the usual inventor’s make-up, the bump of practicality as a sort of appendix, the sense of the business, money value of an invention. Oh, no, I didn’t have it naturally. It was pounded into me by some pretty hard knocks.

The rigid career path of a professor at a modern university is that One Must Build the Big Research Group, recruit doctoral students more vigorously than the head football coach, bombard the federal agencies with grant applications more numerous than the pollen falling from the heavens in spring, and leave the paper writing and the research to the postdocs, research associates, and students who do all the bench work and all the computer programming. A professor is chained to his previous topics by his Big Group, his network of contacts built up laboriously over decades, and the impossibility of large funding except in areas where the grantee has grown the group from a corner of the building to an entire floor. The senior tenure-track faculty at a research university–the “silverbacks” in anthropological jargon–are bound by invisible chains stronger than the strongest steel to a narrow range of what the Prevailing Consensus agrees are Very Important Problems. The aspiring scientist is confronted with the reality that his mentors are all business managers.

The sciences of Natural History and Botany require so much time to be devoted to them that, however pleasing, they may be justly considered as improper objects for the man of business to pursue scientifically, so as to enter into the exact arrangement and classification of the different bodies of the animal, vegetable, and mineral kingdoms. But reading and personal observation will supply him with ample matter for reflection and admiration.

The true business of the philosopher, though not flattering to his vanity, is merely to ascertain, arrange and condense the facts.

The universe is reeking with organic matter. You could say that the universe is in the business of making life—or that God is an organic chemist.

The university’s business is the conservation of useless knowledge; and what the university itself apparently fails to see is that this enterprise is not only noble but indispensable as well, that society can not exist unless it goes on.

There are those who say we cannot afford to invest in science, that support for research is somehow a luxury at moments defined by necessities. I fundamentally disagree. Science is more essential for our prosperity, our security, our health, our environment, and our quality of life than it has ever been before. … we can't allow our nation to fall behind. Unfortunately, that's exactly what's happened. Federal funding in the physical sciences as a portion of our gross domestic product has fallen by nearly half over the past quarter century. Time and again we've allowed the research and experimentation tax credit, which helps businesses grow and innovate, to lapse.

There are three chief requisites for a successful business man. The first is honesty—absolute honesty … the second … is industry … [and] perseverance is the third.

There are three ruling ideas, three so to say, spheres of thought, which pervade the whole body of mathematical science, to some one or other of which, or to two or all three of them combined, every mathematical truth admits of being referred; these are the three cardinal notions, of Number, Space and Order.
Arithmetic has for its object the properties of number in the abstract. In algebra, viewed as a science of operations, order is the predominating idea. The business of geometry is with the evolution of the properties of space, or of bodies viewed as existing in space.

There is a point of view among astronomical researchers that is generally referred to as the Principle of Mediocrity. ... If the Sun and its retinue of worlds is only one system among many, then many other systems will be like ours: home to life. Indeed, to the extent that this is true, we should be prepared for the possibility that, even in the Milky Way galaxy, billions of planets may be carpeted by the dirty, nasty business known as life.

There is waste going on in the business life of our people in many ways—waste both of resources and of opportunities. There is waste of energy due to insufficient occupation, because agriculture gives full employment for only six or seven months in the year. There is waste due to illiteracy, because ninety-four persons out of every hundred are uneducated. There is waste through ignorance of the ways of the civilized people, because we fail to utilize their accumulated asset of wisdom and experience. Waste is also going on through our imperfect acquaintance with the commonplaces of civilization and lack of correct business ideals and business standards in daily life. Mental energy is wasted in caste disputes and village factions. Capital is wasted because money is hoarded instead of being made available for productive purposes. There is waste of health because, although leading moral lives normally, men and women grow prematurely old for want of pride of person and attention to the elementary laws of health. The largest waste of all is the lack of capacity for cooperation, the difficulty of ensuring harmony, sympathy and oneness of feeling, in matters affecting the larger interests of the State.

There’s no question in my mind that the capability of [the space shuttle] to put 65,000 pounds in low earth orbit—to put payloads up there cheaper than we’ve been able to do it before, not having to throw away the booster—will absolutely revolutionize the way we do business here on earth in ways that we just can’t imagine. It will help develop science and technology. With the space shuttle—when we get it operational—we’ll be able to do in 5 or 10 years what it would take us 20 to 30 years to do otherwise in science and technology development.