1097 … Then at Michaelmas, on the 4th before the Nones of October, an uncommon star appeared shining in the evening, and soon going down: it was seen in the south-west, and the light which streamed from it seemed very long, shining towards the south-east; and it appeared after this manner nearly all the week. Many allowed that it was a comet.

1839—The fermentation satire
THE MYSTERY OF ALCOHOLIC FERMENTATION RESOLVED
(Preliminary Report by Letter) Schwindler
I am about to develop a new theory of wine fermentation … Depending on the weight, these seeds carry fermentation to completion somewhat less than as in the beginning, which is understandable … I shall develop a new theory of wine fermentation [showing] what simple means Nature employs in creating the most amazing phenomena. I owe it to the use of an excellent microscope designed by Pistorius.
When brewer’s yeast is mixed with water the microscope reveals that the yeast dissolves into endless small balls, which are scarcely 1/800th of a line in diameter … If these small balls are placed in sugar water, it can be seen that they consist of the eggs of animals. As they expand, they burst, and from them develop small creatures that multiply with unbelievable rapidity in a most unheard of way. The form of these animals differs from all of the 600 types described up until now. They possess the shape of a Beinsdorff still (without the cooling apparatus). The head of the tube is a sort of proboscis, the inside of which is filled with fine bristles 1/2000th of a line long. Teeth and eyes are not discernible; however, a stomach, intestinal canal, anus (a rose red dot), and organs for secretion of urine are plainly discernible. From the moment they are released from the egg one can see these animals swallow the sugar from the solution and pass it to the stomach. It is digested immediately, a process recognized easily by the resultant evacuation of excrements. In a word, these infusors eat sugar, evacuate ethyl alcohol from the intestinal canal, and carbon dioxide from the urinary organs. The bladder, in the filled state, has the form of a champagne bottle; when empty, it is a small button … As soon as the animals find no more sugar present, they eat each other up, which occurs through a peculiar manipulation; everything is digested down to the eggs which pass unchanged through the intestinal canal. Finally, one again fermentable yeast, namely the seed of the animals, which remain over.

The Redwoods

Here, sown by the Creator's hand,
In serried ranks, the Redwoods stand;
No other clime is honored so,
No other lands their glory know.

The greatest of Earth's living forms,
Tall conquerors that laugh at storms;
Their challenge still unanswered rings,
Through fifty centuries of kings.

The nations that with them were young,
Rich empires, with their forts far-flung,
Lie buried now—their splendor gone;
But these proud monarchs still live on.

So shall they live, when ends our day,
When our crude citadels decay;
For brief the years allotted man,
But infinite perennials' span.

This is their temple, vaulted high,
And here we pause with reverent eye,
With silent tongue and awe-struck soul;
For here we sense life's proper goal;

To be like these, straight, true and fine,
To make our world, like theirs, a shrine;
Sink down, oh traveler, on your knees,
God stands before you in these trees.

Atten. Pray of what disease did Mr. Badman die, for now I perceive we are come up to his death? Wise. I cannot so properly say that he died of one disease, for there were many that had consented, and laid their heads together to bring him to his end. He was dropsical, he was consumptive, he was surfeited, was gouty, and, as some say, he had a tang of the pox in his bowels. Yet the captain of all these men of death that came against him to take him away, was the consumption, for it was that that brought him down to the grave.

Dans les sciences physiques en général, on ait souvent supposé au lieu de conclure; que les suppositions transmises d’âge en âge, soient devenues de plus en plus imposantes par le poids des autorités qu'elles ont acquises , & qu'elles ayent enfin été adoptées & regardées comme des vérités fondamentales, même par de très-bons esprits.
In the science of physics in general, men have so often formed suppositions, instead of drawing conclusions. These suppositions, handed down from one age to another, acquire additional weight from the authorities by which they are supported, till at last they are received, even by men of genius, as fundamental truths.

Dilbert: Maybe I’m unlucky in love because I’m so knowledgeable about science that I intimidate people. Their intimidation becomes low self-esteem, then they reject me to protect their egos.
Dogbert: Occam’s Razor.
Dilbert: What is “Occam's Razor”?
Dogbert: A guy named Occam had a rule about the world. Basically he said that when there are multiple explanations for something the simplest explanation is usually correct. The simplest explanation for your poor love life is that you’re immensely unattractive.
Dilbert: Maybe Occam had another rule that specifically exempted this situation, but his house burned down with all his notes. Then he forgot.
Dogbert: Occam’s Razor.
Dilbert: I’m an idiot.
Dogbert: I don’t think we can rule it out at this point.

Il n'y a qu'un demi-siècle, un orateur chrétien, se défiant des hommes de la science leur disait: 'Arrêtez-vous enfin, et ne creusez pas jusqu'aux enfers.' Aujourd'hui, Messieurs, rassurés sur l'inébranlable constance de notre foi, nous vous disons: creusez, creusez encore; plus vous descendrez, plus vous rapprocherez du grand mystère de l'impuissance de l'homme et de la vérité de la religion. Creusez donc, creusez toujours,mundum tradidit disputationibus eorum; et quand la science aura donné son dernier coup de marteau sur les fondements de la terre, vous pourrez à la lueur du feu qu'il fera jaillir, lire encore l'idée de Dieu et contempler l'empreinte de sa main.
Only a half-century ago, a Christian speaker, mistrustful of men of science told them: 'Stop finally, and do not dig to hell.' Today, gentlemen, reassured about the steadfastness of our unshakeable faith, we say: dig, dig again; the further down you, the closer you come to the great mystery of the impotence of man and truth of religion. So dig, always dig: and when science has stuck its final hammer blow on the bosom of the earth, you will be able to ignite a burst of light, read furthermore the mind of God and contemplate the imprint of His hand.

Indiana Jones: Archaeology is the search for fact… not truth. If it’s truth you're looking for, Dr. Tyree’s philosophy class is right down the hall. … So forget any ideas you've got about lost cities, exotic travel, and digging up the world. We do not follow maps to buried treasure, and “X” never, ever marks the spot. Seventy percent of all archaeology is done in the library. Research. Reading.

Nulla (enim) res tantum ad dicendum proficit, quantum scriptio
Nothing so much assists learning as writing down what we wish to remember.

Question: If you walk on a dry path between two walls a few feet apart, you hear a musical note or “ring” at each footstep. Whence comes this?
Answer: This is similar to phosphorescent paint. Once any sound gets between two parallel reflectors or walls, it bounds from one to the other and never stops for a long time. Hence it is persistent, and when you walk between the walls you hear the sounds made by those who walked there before you. By following a muffin man down the passage within a short time you can hear most distinctly a musical note, or, as it is more properly termed in the question, a “ring” at every (other) step.

Socrates: Shall we set down astronomy among the objects of study? Glaucon: I think so, to know something about the seasons, the months and the years is of use for military purposes, as well as for agriculture and for navigation. Socrates: It amuses me to see how afraid you are, lest the common herd of people should accuse you of recommending useless studies.

[In refutation of evolution] There is not enough evidence, consistent evidence to make it as fact, and I say that because for theory to become a fact, it needs to consistently have the same results after it goes through a series of tests. The tests that they put—that they use to support evolution do not have consistent results. Now too many people are blindly accepting evolution as fact. But when you get down to the hard evidence, it’s merely a theory.
[In favor of the teaching of creationism alongside evolution in schools.]

A committee is a cul-de-sac down which ideas are lured and then quietly strangled.

A discussion between Haldane and a friend began to take a predictable turn. The friend said with a sigh, “It’s no use going on. I know what you will say next, and I know what you will do next.” The distinguished scientist promptly sat down on the floor, turned two back somersaults, and returned to his seat. “There,” he said with a smile. “That’s to prove that you’re not always right.”

A farmer believes what goes down must come up.

A few days afterwards, I went to him [the same actuary referred to in another quote] and very gravely told him that I had discovered the law of human mortality in the Carlisle Table, of which he thought very highly. I told him that the law was involved in this circumstance. Take the table of the expectation of life, choose any age, take its expectation and make the nearest integer a new age, do the same with that, and so on; begin at what age you like, you are sure to end at the place where the age past is equal, or most nearly equal, to the expectation to come. “You don’t mean that this always happens?”—“Try it.” He did try, again and again; and found it as I said. “This is, indeed, a curious thing; this is a discovery!” I might have sent him about trumpeting the law of life: but I contented myself with informing him that the same thing would happen with any table whatsoever in which the first column goes up and the second goes down.

A fish rots from the head down.

A huge net is being dragged across the sea floor, destroying everything in its path. Ahead of it bloom undersea forests and their hundreds and thousands of living creatures, both plant and animal; behind it is a desert. The net is pulled to the surface and most of the dead and dying life forms in it are thrown out. A few marketable species are retained. [Trawling] is like taking a front-end loader and scraping up your entire front garden and shredding it, keeping a few pebbles, and dumping the rest of it down the drain.

A layman will no doubt find it hard to understand how pathological disorders of the body and mind can be eliminated by 'mere' words. He will feel that he is being asked to believe in magic. And he will not be so very wrong, for the words which we use in our everyday speech are nothing other than watered-down magic. But we shall have to follow a roundabout path in order to explain how science sets about restoring to words a part at least of their former magical power.

A man is flying in a hot air balloon and realizes he is lost. He reduces height, spots a man down below and asks,“Excuse me, can you help me? I promised to return the balloon to its owner, but I don’t know where I am.”
The man below says: “You are in a hot air balloon, hovering approximately 350 feet above mean sea level and 30 feet above this field. You are between 40 and 42 degrees north latitude, and between 58 and 60 degrees west longitude.”
“You must be an engineer,” says the balloonist.
“I am,” replies the man.“How did you know?”
“Well,” says the balloonist, “everything you have told me is technically correct, but I have no idea what to make of your information, and the fact is I am still lost.”
The man below says, “You must be a manager.”
“I am,” replies the balloonist,“but how did you know?”
“Well,” says the engineer,“you don’t know where you are, or where you are going. You have made a promise which you have no idea how to keep, and you expect me to solve your problem.The fact is you are in the exact same position you were in before we met, but now it is somehow my fault.”

A mathematician who can only generalise is like a monkey who can only climb UP a tree. ... And a mathematician who can only specialise is like a monkey who can only climb DOWN a tree. In fact neither the up monkey nor the down monkey is a viable creature. A real monkey must find food and escape his enemies and so must be able to incessantly climb up and down. A real mathematician must be able to generalise and specialise. ... There is, I think, a moral for the teacher. A teacher of traditional mathematics is in danger of becoming a down monkey, and a teacher of modern mathematics an up monkey. The down teacher dishing out one routine problem after another may never get off the ground, never attain any general idea. and the up teacher dishing out one definition after the other may never climb down from his verbiage, may never get down to solid ground, to something of tangible interest for his pupils.

A mouse can fall down a mine shaft a third of a mile deep without injury. A rat falling the same distance would break his bones; a man would simply splash ... Elephants have their legs thickened to an extent that seems disproportionate to us, but this is necessary if their unwieldly bulk is to be moved at all ... A 60-ft. man would weigh 1000 times as much as a normal man, but his thigh bone would have its area increased by only 100 times ... Consequently such an unfortunate monster would break his legs the moment he tried to move.
Expressing, in picturesque terms, the strength of an organism relative to its bulk.

A new species develops if a population which has become geographically isolated from its parental species acquires during this period of isolation characters which promote or guarantee reproductive isolation when the external barriers break down.

A scientist strives to understand the work of Nature. But with our insufficient talents as scientists, we do not hit upon the truth all at once. We must content ourselves with tracking it down, enveloped in considerable darkness, which leads us to make new mistakes and errors. By diligent examination, we may at length little by little peel off the thickest layers, but we seldom get the core quite free, so that finally we have to be satisfied with a little incomplete knowledge.

A small cabin stands in the Glacier Peak Wilderness, about a hundred yards off a trail that crosses the Cascade Range. In midsummer, the cabin looked strange in the forest. It was only twelve feet square, but it rose fully two stories and then had a high and steeply peaked roof. From the ridge of the roof, moreover, a ten-foot pole stuck straight up. Tied to the top of the pole was a shovel. To hikers shedding their backpacks at the door of the cabin on a cold summer evening—as the five of us did—it was somewhat unnerving to look up and think of people walking around in snow perhaps thirty-five feet above, hunting for that shovel, then digging their way down to the threshold.

A story about the Jack Spratts of medicine [was] told recently by Dr. Charles H. Best, co-discoverer of insulin. He had been invited to a conference of heart specialists in North America. On the eve of the meeting, out of respect for the fat-clogs-the-arteries theory, the delegates sat down to a special banquet served without fats. It was unpalatable but they all ate it as a duty. Next morning Best looked round the breakfast room and saw these same specialists—all in the 40-60 year old, coronary age group—happily tucking into eggs, bacon, buttered toast and coffee with cream.

A tree is beautiful, but what’s more, it has a right to life; like water, the sun and the stars, it is essential. Life on earth is inconceivable without trees. Forests create climate, climate influences peoples’ character, and so on and so forth. There can be neither civilization nor happiness if forests crash down under the axe, if the climate is harsh and severe, if people are also harsh and severe. ... What a terrible future!

A weird happening has occurred in the case of a lansquenet named Daniel Burghammer, of the squadron of Captain Burkhard Laymann Zu Liebenau, of the honorable Madrucci Regiment in Piadena, in Italy. When the same was on the point of going to bed one night he complained to his wife, to whom he had been married by the Church seven years ago, that he had great pains in his belly and felt something stirring therein. An hour thereafter he gave birth to a child, a girl. When his wife was made aware of this, she notified the occurrence at once. Thereupon he was examined and questioned. … He confessed on the spot that he was half man and half woman and that for more than seven years he had served as a soldier in Hungary and the Netherlands… . When he was born he was christened as a boy and given in baptism the name of Daniel… . He also stated that while in the Netherlands he only slept once with a Spaniard, and he became pregnant therefrom. This, however, he kept a secret unto himself and also from his wife, with whom he had for seven years lived in wedlock, but he had never been able to get her with child… . The aforesaid soldier is able to suckle the child with his right breast only and not at all on the left side, where he is a man. He has also the natural organs of a man for passing water. Both are well, the child is beautiful, and many towns have already wished to adopt it, which, however, has not as yet been arranged. All this has been set down and described by notaries. It is considered in Italy to be a great miracle, and is to be recorded in the chronicles. The couple, however, are to be divorced by the clergy.

About the year 1772, being then an apprentice to a wheel-wright, or wagon maker, I laboured to discover some means of propelling land carriages without animal power. … one of my brothers [told me of] blacksmith’s boys, who, for amusement, had stopped up the touch hole of a gun barrel, then put in about a gill of water, and rammed down a tight wad; after which they put the breech in the smith’s fire, when it discharged itself with as loud a crack as if it had been loaded with powder. It immediately occurred to me, that here was the power to propel any wagon, if I could only apply it.

Across the road from my cabin was a huge clear-cut—hundreds of acres of massive spruce stumps interspersed with tiny Douglas firs—products of what they call “Reforestation,” which I guess makes the spindly firs en masse a “Reforest,” which makes an individual spindly fir a “Refir,” which means you could say that Weyerhauser, who owns the joint, has Refir Madness, since they think that sawing down 200-foot-tall spruces and replacing them with puling 2-foot Refirs is no different from farming beans or corn or alfalfa. They even call the towering spires they wipe from the Earth's face forever a “crop”--as if they'd planted the virgin forest! But I'm just a fisherman and may be missing some deeper significance in their nomenclature and stranger treatment of primordial trees.

Active conservation [of gorillas] involves simply going out into the forest, on foot, day after day after day, attempting to capture poachers, killing—regretfully—poacher dogs, which spread rabies within the park, and cutting down traps.

Adam is fading out. It is on account of Darwin and that crowd. I can see that he is not going to last much longer. There's a plenty of signs. He is getting belittled to a germ—a little bit of a speck that you can't see without a microscope powerful enough to raise a gnat to the size of a church. They take that speck and breed from it: first a flea; then a fly, then a bug, then cross these and get a fish, then a raft of fishes, all kinds, then cross the whole lot and get a reptile, then work up the reptiles till you've got a supply of lizards and spiders and toads and alligators and Congressmen and so on, then cross the entire lot again and get a plant of amphibiums, which are half-breeds and do business both wet and dry, such as turtles and frogs and ornithorhyncuses and so on, and cross-up again and get a mongrel bird, sired by a snake and dam'd by a bat, resulting in a pterodactyl, then they develop him, and water his stock till they've got the air filled with a million things that wear feathers, then they cross-up all the accumulated animal life to date and fetch out a mammal, and start-in diluting again till there's cows and tigers and rats and elephants and monkeys and everything you want down to the Missing Link, and out of him and a mermaid they propagate Man, and there you are! Everything ship-shape and finished-up, and nothing to do but lay low and wait and see if it was worth the time and expense.

After a duration of a thousand years, the power of astrology broke down when, with Copernicus, Kepler, and Galileo, the progress of astronomy overthrew the false hypothesis upon which the entire structure rested, namely the geocentric system of the universe. The fact that the earth revolves in space intervened to upset the complicated play of planetary influences, and the silent stars, related to the unfathomable depths of the sky, no longer made their prophetic voices audible to mankind. Celestial mechanics and spectrum analysis finally robbed them of their mysterious prestige.

After a tremendous task has been begun in our time, first by Copernicus and then by many very learned mathematicians, and when the assertion that the earth moves can no longer be considered something new, would it not be much better to pull the wagon to its goal by our joint efforts, now that we have got it underway, and gradually, with powerful voices, to shout down the common herd, which really does not weigh arguments very carefully?

After what has been premised, I think we may lay down the following Conclusions. First, It is plain Philosophers amuse themselves in vain, when they inquire for any natural efficient Cause, distinct from a Mind or Spirit. Secondly, Considering the whole Creation is the Workmanship of a wise and good Agent, it should seem to become Philosophers, to employ their Thoughts (contrary to what some hold) about the final Causes of Things: And I must confess, I see no reason, why pointing out the various Ends, to which natural Things are adapted and for which they were originally with unspeakable Wisdom contrived, should not be thought one good way of accounting for them, and altogether worthy a Philosopher.

All our words are but crumbs that fall down from the feast of the mind.

All over the world there lingers on the memory of a giant tree, the primal tree, rising up from the centre of the Earth to the heavens and ordering the universe around it. It united the three worlds: its roots plunged down into subterranean abysses, Its loftiest branches touched the empyrean. Thanks to the Tree, it became possible to breathe the air; to all the creatures that then appeared on Earth it dispensed its fruit, ripened by the sun and nourished by the water which it drew from the soil. From the sky it attracted the lightning from which man made fire and, beckoning skyward, where clouds gathered around its fall. The Tree was the source of all life, and of all regeneration. Small wonder then that tree-worship was so prevalent in ancient times.

All the real true knowledge we have of Nature is intirely experimental, insomuch that, how strange soever the assertion seems, we may lay this down as the first fundamental unerring rule in physics, That it is not within the compass of human understanding to assign a purely speculative reason for any one phaenomenon in nature.

An epidemiologist is a doctor broken down by age and sex.

An iron rod being placed on the outside of a building from the highest part continued down into the moist earth, in any direction strait or crooked, following the form of the roof or other parts of the building, will receive the lightning at its upper end, attracting it so as to prevent it's striking any other part; and, affording it a good conveyance into the earth, will prevent its damaging any part of the building.

An old medical friend gave me some excellent practical advice. He said: “You will have for some time to go much oftener down steps than up steps. Never mind! win the good opinions of washerwomen and such like, and in time you will hear of their recommendations of you to the wealthier families by whom they are employed.” I did so, and found it succeed as predicted.
[On beginning a medical practice.]

And from this such small difference of eight minutes [of arc] it is clear why Ptolemy, since he was working with bisection [of the linear eccentricity], accepted a fixed equant point… . For Ptolemy set out that he actually did not get below ten minutes [of arc], that is a sixth of a degree, in making observations. To us, on whom Divine benevolence has bestowed the most diligent of observers, Tycho Brahe, from whose observations this eight-minute error of Ptolemy’s in regard to Mars is deduced, it is fitting that we accept with grateful minds this gift from God, and both acknowledge and build upon it. So let us work upon it so as to at last track down the real form of celestial motions (these arguments giving support to our belief that the assumptions are incorrect). This is the path I shall, in my own way, strike out in what follows. For if I thought the eight minutes in [ecliptic] longitude were unimportant, I could make a sufficient correction (by bisecting the [linear] eccentricity) to the hypothesis found in Chapter 16. Now, because they could not be disregarded, these eight minutes alone will lead us along a path to the reform of the whole of Astronomy, and they are the matter for a great part of this work.

And it shall come to pass in that day, saith the Lord God, that I will cause the sun to go down at noon, and I will darken the earth in the clear day.

Andrade [who was looking after wartime inventions] is like an inverted Micawber, waiting for something to turn down.

Another error is a conceit that … the best has still prevailed and suppressed the rest: so as, if a man should begin the labor of a new search, he were but like to light upon somewhat formerly rejected, and by rejection brought into oblivion; as if the multitude, or the wisest for the multitude’s sake, were not ready to give passage rather to that which is popular and superficial, than to that which is substantial and profound: for the truth is, that time seemeth to be of the nature of a river or stream, which carrieth down to us that which is light and blown up, and sinketh and drowneth that which is weighty and solid.

Any fool can destroy trees. They cannot run away; and if they could, they would still be destroyed,—chased and hunted down as long as fun or a dollar could be got out of their bark hides, branching horns, or magnificent bole backbones. Few that fell trees plant them; nor would planting avail much towards getting back anything like the noble primeval forests. During a man’s life only saplings can be grown, in the place of the old trees—tens of centuries old—that have been destroyed.

Anyone who writes about science must know about science, which cuts down competition considerably.

Archaeology is the science that proves you can't keep a good man down.

Archaeology is the science that proves you can’t keep a good man down.

Around here, however, we don't look backwards for very long. We keep moving forward, opening up new doors, and doing new things, because we're curious and curiosity keeps leading us down new paths.

As I looked down, I saw a large river meandering slowly along for miles, passing from one country to another without stopping. I also saw huge forests, extending along several borders. And I watched the extent of one ocean touch the shores of separate continents. Two words leaped to mind as I looked down on all this: commonality and interdependence. We are one world.

As the nineteenth century drew to a close, scientists could reflect with satisfaction that they had pinned down most of the mysteries of the physical world: electricity, magnetism, gases, optics, acoustics, kinetics and statistical mechanics ... all had fallen into order before the. They had discovered the X ray, the cathode ray, the electron, and radioactivity, invented the ohm, the watt, the Kelvin, the joule, the amp, and the little erg.

At the planet’s very heart lies a solid rocky core, at least five times larger than Earth, seething with the appalling heat generated by the inexorable contraction of the stupendous mass of material pressing down to its centre. For more than four billion years Jupiter’s immense gravitational power has been squeezing the planet slowly, relentlessly, steadily, converting gravitational energy into heat, raising the temperature of that rocky core to thirty thousand degrees, spawning the heat flow that warms the planet from within. That hot, rocky core is the original protoplanet seed from the solar system’s primeval time, the nucleus around which those awesome layers of hydrogen and helium and ammonia, methane, sulphur compounds and water have wrapped themselves.

At this point, however, I have no intention whatever of criticizing the false teachings of Galen, who is easily first among the professors of dissection, for I certainly do not wish to start off by gaining a reputation for impiety toward him, the author of all good things, or by seeming insubordinate to his authority. For I am well aware how upset the practitioners (unlike the followers of Aristotle) invariably become nowadays, when they discover in the course of a single dissection that Galen has departed on two hundred or more occasions from the true description of the harmony, function, and action of the human parts, and how grimly they examine the dissected portions as they strive with all the zeal at their command to defend him. Yet even they, drawn by their love of truth, are gradually calming down and placing more faith in their own not ineffective eyes and reason than in Galen’s writings.

Away, away, from men and towns,
To the wild wood and the downs,—
To the silent wilderness,
Where the soul need not repress
Its music.

Bad science contributes to the steady dumbing down of our nation. Crude beliefs get transmitted to political leaders and the result is considerable damage to society. We see this happening now in the rapid rise of the religious right and how it has taken over large segments of the Republican Party.

Before I built a wall I’d ask to know
What I was walling in or walling out,
And to whom I was like to give offence.
Something there is that doesn’t love a wall,
That wants it down.

Being in love with the one parent and hating the other are among the essential constituents of the stock of psychical impulses which is formed at that time and which is of such importance in determining the symptoms of the later neurosis... This discovery is confirmed by a legend that has come down to us from classical antiquity: a legend whose profound and universal power to move can only be understood if the hypothesis I have put forward in regard to the psychology of children has an equally universal validity. What I have in mind is the legend of King Oedipus and Sophocles' drama which bears his name.

Biological diversity is the key to the maintenance of the world as we know it. Life in a local site struck down by a passing storm springs back quickly: opportunistic species rush in to fill the spaces. They entrain the succession that circles back to something resembling the original state of the environment.

Bodies, projected in our air, suffer no resistance but from the air. Withdraw the air, as is done in Mr. Boyle's vacuum, and the resistance ceases. For in this void a bit of fine down and a piece of solid gold descend with equal velocity.

Boiled down to one sentence, my message is the unboundedness of life and the unboundedness of human destiny.

Bowing to the reality of harried lives, Rudwick recognizes that not everyone will read every word of the meaty second section; he even explicitly gives us permission to skip if we get ‘bogged down in the narrative.’ Readers absolutely must not do such a thing; it should be illegal. The publisher should lock up the last 60 pages, and deny access to anyone who doesn’t pass a multiple-choice exam inserted into the book between parts two and three.

Built up of carbon, hydrogen, oxygen, nitrogen, together with traces of a few other elements, yet of a complexity of structure that has hitherto resisted all attempts at complete analysis, protoplasm is at once the most enduring and the most easily destroyed of substances; its molecules are constantly breaking down to furnish the power for the manifestations of vital phenomena, and yet, through its remarkable property of assimilation, a power possessed by nothing else upon earth, it constantly builds up its substance anew from the surrounding medium.

Buoyed by water, he can fly in any direction—up, down, sideways—by merely flipping his hand. Under water, man becomes an archangel.

But as no two (theoreticians) agree on this (skin friction) or any other subject, some not agreeing today with what they wrote a year ago, I think we might put down all their results, add them together, and then divide by the number of mathematicians, and thus find the average coefficient of error. (1908)

But however secure and well-regulated civilized life may become, bacteria, Protozoa, viruses, infected fleas, lice, ticks, mosquitoes, and bedbugs will always lurk in the shadows ready to pounce when neglect, poverty, famine, or war lets down the defenses.

But in my opinion we can now be assured sufficiently that no animals, however small they may be, take their origin in putrefaction, but exclusively in procreation… For seeing that animals, from the largest down to the little despised animal, the flea, have animalcules in their semen, seeing also that some of the vessels of the lungs of horses and cows consist of rings and that these rings can occur on the flea's veins, why cannot we come to the conclusion that as well as the male sperm of that large animal the horse and similar animals, and of all manner of little animals, the flea included, is furnished with animalcules (and other intestines, for I have often been astonished when I beheld the numerous vessels in a flea), why, I say should not the male sperm of the smallest animals, smaller than a flea may even the very smallest animalcules have the perfection that we find in a flea.

But when you come right down to it, the reason that we did this job is because it was an organic necessity. If you are a scientist you cannot stop such a thing. If you are a scientist you believe that it is good to find out how the world works; that it is good to find out what the realities are; that it is good to turn over to mankind at large the greatest possible power to control the world and to deal with it according to its lights and values.
Regarding the atomic bomb project.

Cat-Ideas and Mouse-Ideas. We can never get rid of mouse-ideas completely, they keep turning up again and again, and nibble, nibble—no matter how often we drive them off. The best way to keep them down is to have a few good strong cat-ideas which will embrace them and ensure their not reappearing till they do so in another shape.

Charles Darwin [is my personal favorite Fellow of the Royal Society]. I suppose as a physical scientist I ought to have chosen Newton. He would have won hands down in an IQ test, but if you ask who was the most attractive personality then Darwin is the one you'd wish to meet. Newton was solitary and reclusive, even vain and vindictive in his later years when he was president of the society.

Chemistry dissolves the goddess in the alembic,
Venus, the white queen, the universal matrix,
Down to the molecular hexagons and carbon-chains.

Conservation and rural-life policies are really two sides of the same policy; and down at the bottom this policy rests upon the fundamental law that neither man nor nation can prosper unless, in dealing with the present, thought is steadily given for the future.

Do the day’s work. If it be to protect the rights of the weak, whoever objects, do it. If it be to help a powerful corporation better to serve the people, whatever the opposition, do that. Expect to be called a stand-patter, but don’t be a stand-patter. Expect to be called a demagogue, but don’t be a demagogue. Don’t hesitate to be as revolutionary as science. Don’t hesitate to be as reactionary as the multiplication table. Don’t expect to build up the weak by pulling down the strong. Don’t hurry to legislate. Give administration a chance to catch up with legislation.

Doctor Johnson said, that in sickness there were three things that were material; the physician, the disease, and the patient: and if any two of these joined, then they get the victory; for, Ne Hercules quidem contra duos [Not even Hercules himself is a match for two]. If the physician and the patient join, then down goes the disease; for then the patient recovers: if the physician and the disease join, that is a strong disease; and the physician mistaking the cure, then down goes the patient: if the patient and the disease join, then down goes the physician; for he is discredited.

Does it seem all but incredible to you that intelligence should travel for two thousand miles, along those slender copper lines, far down in the all but fathomless Atlantic; never before penetrated … save when some foundering vessel has plunged with her hapless company to the eternal silence and darkness of the abyss? Does it seem … but a miracle … that the thoughts of living men … should burn over the cold, green bones of men and women, whose hearts, once as warm as ours, burst as the eternal gulfs closed and roared over them centuries ago?

Don't ever take a fence down until you know the reason why it was put up.

Don’t worry about people stealing an idea. If it’s original, you will have to ram it down their throats.

Dr Bell fell down the well
And broke his collar bone
Doctors should attend the sick
And leave the well alone.

During the time of the Deluge, whilst the Water was out upon, and covered the Terrestrial Globe, … all Fossils whatever that had before obtained any Solidity, were totally dissolved, and their constituent Corpuscles all disjoyned, their Cohesion perfectly ceasing … [A]nd, to be short, all Bodies whatsoever that were either upon the Earth, or that constituted the Mass of it, if not quite down to the Abyss, yet at least to the greatest depth we ever dig: I say all these were assumed up promiscuously into the Water, and sustained in it, in such a manner that the Water, and Bodies in it, together made up one common confused Mass. That at length all the Mass that was thus borne up in the Water, was again precipitated and subsided towards the bottom. That this subsidence happened generally, and as near as possibly could be expected in so great a Confusion, according to the laws of Gravity.

Each time one of the medicine men dies, it's as if a library has burned down.
{Referring to potential knowledge from indiginous peoples of the medicinal value of tropical plants, speaking as director of the plant program of the World Wildlife Fund and having spent many months living with the Tirio tribe on the Suriname-Brazil border.]

Education is the process of driving a set of prejudices down your throat.

Even fairly good students, when they have obtained the solution of the problem and written down neatly the argument, shut their books and look for something else. Doing so, they miss an important and instructive phase of the work. ... A good teacher should understand and impress on his students the view that no problem whatever is completely exhausted.

Eventually the process of aging, which is unlikely to be simple, should be understandable. Hopefully some of its processes can be slowed down or avoided. In fact, in the next century, we shall have to tackle the question of the preferred form of death.

Every living being is also a fossil. Within it, all the way down to the microscopic structure of its proteins, it bears the traces if not the stigmata of its ancestry.

Every theory of love, from Plato down, teaches that each individual loves in the other sex what he lacks in himself.

Every time we get slapped down, we can say, “Thank you Mother Nature,” because it means we’re about to learn something important.

Everybody likes to hear about a man laying down his life for his country, but nobody wants to hear about a country giving her shirt for her planet.

Everything material which is the subject of knowledge has number, order, or position; and these are her first outlines for a sketch of the universe. If our feeble hands cannot follow out the details, still her part has been drawn with an unerring pen, and her work cannot be gainsaid. So wide is the range of mathematical sciences, so indefinitely may it extend beyond our actual powers of manipulation that at some moments we are inclined to fall down with even more than reverence before her majestic presence. But so strictly limited are her promises and powers, about so much that we might wish to know does she offer no information whatever, that at other moments we are fain to call her results but a vain thing, and to reject them as a stone where we had asked for bread. If one aspect of the subject encourages our hopes, so does the other tend to chasten our desires, and he is perhaps the wisest, and in the long run the happiest, among his fellows, who has learned not only this science, but also the larger lesson which it directly teaches, namely, to temper our aspirations to that which is possible, to moderate our desires to that which is attainable, to restrict our hopes to that of which accomplishment, if not immediately practicable, is at least distinctly within the range of conception.

Evolution ... is really two theories, the vague theory and the precise theory. The vague theory has been abundantly proved.... The precise theory has never been proved at all. However, like relativity, it is accepted on faith.... On getting down to actual details, difficulties begin.

Evolution is a blind giant who rolls a snowball down a hill. The ball is made of flakes—circumstances. They contribute to the mass without knowing it. They adhere without intention, and without foreseeing what is to result. When they see the result they marvel at the monster ball and wonder how the contriving of it came to be originally thought out and planned. Whereas there was no such planning, there was only a law: the ball once started, all the circumstances that happened to lie in its path would help to build it, in spite of themselves.

Evolution is an obstacle course not a freeway; the correct analogue for long-term success is a distant punt receiver evading legions of would-be tacklers in an oddly zigzagged path toward a goal, not a horse thundering down the flat.

Falling in love is not at all the most stupid thing that people do, but gravitation cannot be held responsible for it.
Scribbled by Einstein on a letter received during a visit to England (1933) from a man who suggested that gravity meant that as the world rotated people were sometimes upside down, horizontal, or at 'left angles' and that perhaps, this disorientation explained why people do foolish things like falling in love.

Florey was not an easy personality. His drive and ambition were manifest from the day he arrived ... He could be ruthless and selfish; on the other hand, he could show kindliness, a warm humanity and, at times, sentiment and a sense of humour. He displayed utter integrity and he was scathing of humbug and pretence. His attitude was always—&ldqo;You must take me as you find me” But to cope with him at times, you had to do battle, raise your voice as high as his and never let him shout you down. You had to raise your pitch to his but if you insisted on your right he was always, in the end, very fair. I must say that at times, he went out of his way to cut people down to size with some very destructive criticism. But I must also say in the years I knew him he did not once utter a word of praise about himself.

For it is necessary in every practical science to proceed in a composite (i.e. deductive) manner. On the contrary in speculative science, it is necessary to proceed in an analytical manner by breaking down the complex into elementary principles.

For nothing is fixed, forever and forever and forever, it is not fixed; the earth is always shifting, the light is always changing, the sea does not cease to grind down rock. Generations do not cease to be born, and we are responsible to them because we are the only witnesses they have. The sea rises, the light fails, lovers cling to each other, and children cling to us. The moment we cease to hold each other, the sea engulfs us and the light goes out.

Forward, forward let us range,
Let the great world spin for ever down the ringing grooves of change.

From my earliest childhood I nourished and cherished the desire to make a creditable journey in a new country, and write such a respectable account of its natural history as should give me a niche amongst the scientific explorers of the globe I inhabit, and hand my name down as a useful contributor of original matter.

From the infinitely great down to the infinitely small, all things are subject to [the laws of nature]. The sun and the planets follow the laws discovered by Newton and Laplace, just as the atoms in their combinations follow the laws of chemistry, as living creatures follow the laws of biology. It is only the imperfections of the human mind which multiply the divisions of the sciences, separating astronomy from physics or chemistry, the natural sciences from the social sciences. In essence, science is one. It is none other than the truth.

From thus meditating on the great similarity of the structure of the warm-blooded animals, and at the same time of the great changes they undergo both before and after their nativity; and by considering in how minute a portion of time many of the changes of animals above described have been produced; would it be too bold to imagine that, in the great length of time since the earth began to exist, perhaps millions of ages before the commencement of the history of mankind would it be too bold to imagine that all warm-blooded animals have arisen from one living filament, which THE GREAT FIRST CAUSE endued with animality, with the power of acquiring new parts, attended with new propensities, directed by irritations, sensations, volitions and associations, and thus possessing the faculty of continuing to improve by its own inherent activity, and of delivering down these improvements by generation to its posterity, world without end!

Genuine religion has its root deep down in the heart of humanity and in the reality of things. It is not surprising that by our methods we fail to grasp it: the actions of the Deity make no appeal to any special sense, only a universal appeal; and our methods are, as we know, incompetent to detect complete uniformity. There is a principle of Relativity here, and unless we encounter flaw or jar or change, nothing in us responds; we are deaf and blind therefore to the Immanent Grandeur, unless we have insight enough to recognise in the woven fabric of existence, flowing steadily from the loom in an infinite progress towards perfection, the ever-growing garment of a transcendent God.

Geologists have not been slow to admit that they were in error in assuming that they had an eternity of past time for the evolution of the earth's history. They have frankly acknowledged the validity of the physical arguments which go to place more or less definite limits to the antiquity of the earth. They were, on the whole, disposed to acquiesce in the allowance of 100 millions of years granted to them by Lord Kelvin, for the transaction of the whole of the long cycles of geological history. But the physicists have been insatiable and inexorable. As remorseless as Lear's daughters, they have cut down their grant of years by successive slices, until some of them have brought the number to something less than ten millions. In vain have the geologists protested that there must somewhere be a flaw in a line of argument which tends to results so entirely at variance with the strong evidence for a higher antiquity, furnished not only by the geological record, but by the existing races of plants and animals. They have insisted that this evidence is not mere theory or imagination, but is drawn from a multitude of facts which become hopelessly unintelligible unless sufficient time is admitted for the evolution of geological history. They have not been able to disapprove the arguments of the physicists, but they have contended that the physicists have simply ignored the geological arguments as of no account in the discussion.

Getting to the summit is optional, getting down is mandatory.

God is a philosophical black hole—the point where reason breaks down.

Gravity, a mere nuisance to Christian, was a terror to Pope, Pagan, and Despair. You can drop a mouse down a thousand-yard mine shaft; and, on arriving at the bottom, it gets a slight shock and walks away, provided that the ground is fairly soft. A rat is killed, a man is broken, a horse splashes.

Heraclitus son of Bloson (or, according to some, of Herakon) of Ephesus. This man was at his prime in the 69th Olympiad. He grew up to be exceptionally haughty and supercilious, as is clear also from his book, in which he says: “Learning of many things does not teach intelligence; if so it would have taught Hesiod and Pythagoras, and again Xenophanes and Hecataeus.” … Finally he became a misanthrope, withdrew from the world, and lived in the mountains feeding on grasses and plants. However, having fallen in this way into a dropsy he came down to town and asked the doctors in a riddle if they could make a drought out of rainy weather. When they did not understand he buried himself in a cow-stall, expecting that the dropsy would be evaporated off by the heat of the manure; but even so he failed to effect anything, and ended his life at the age of sixty.

His [Marvin Minsky’s] basic interest seemed to be in the workings of the human mind and in making machine models of the mind. Indeed, about that time he and a friend made one of the first electronic machines that could actually teach itself to do something interesting. It monitored electronic “rats” that learned to run mazes. It was being financed by the Navy. On one notable occasion, I remember descending to the basement of Memorial Hall, while Minsky worked on it. It had an illuminated display panel that enabled one to follow the progress of the “rats.” Near the machine was a hamster in a cage. When the machine blinked, the hamster would run around its cage happily. Minsky, with his characteristic elfin grin, remarked that on a previous day the Navy contract officer had been down to see the machine. Noting the man’s interest in the hamster, Minsky had told him laconically, “The next one we build will look like a bird.”

Houses were knocked down... enormous heaps of earth and clay thrown up; buildings that were undermined and shaking, propped up by great beams of wood... The yet unfinished and unopened Railway was in progress.

How can a man sit down and quietly pare his nails, while the earth goes gyrating ahead amid such a din of sphere music, whirling him along about her axis some twenty-four thousand miles between sun and sun, but mainly in a circle some two millions of miles actual progress? And then such a hurly-burly on the surface …. Can man do less than get up and shake himself?

How did I discover saccharin? Well, it was partly by accident and partly by study. I had worked a long time on the compound radicals and substitution products of coal tar... One evening I was so interested in my laboratory that I forgot about my supper till quite late, and then rushed off for a meal without stopping to wash my hands. I sat down, broke a piece of bread, and put it to my lips. It tasted unspeakably sweet. I did not ask why it was so, probably because I thought it was some cake or sweetmeat. I rinsed my mouth with water, and dried my moustache with my napkin, when, to my surprise the napkin tasted sweeter than the bread. Then I was puzzled. I again raised my goblet, and, as fortune would have it, applied my mouth where my fingers had touched it before. The water seemed syrup. It flashed on me that I was the cause of the singular universal sweetness, and I accordingly tasted the end of my thumb, and found it surpassed any confectionery I had ever eaten. I saw the whole thing at once. I had discovered some coal tar substance which out-sugared sugar. I dropped my dinner, and ran back to the laboratory. There, in my excitement, I tasted the contents of every beaker and evaporating dish on the table.

How I hate the man who talks about the “brute creation”, with an ugly emphasis on Brute. Only Christians are capable of it. As for me, I am proud of my close kinship with other animals. I take a jealous pride in my Simian ancestry. I like to think that I was once a magnificent hairy fellow living in the trees and that my frame has come down through geological time via sea jelly and worms and Amphioxus, Fish, Dinosaurs, and Apes. Who would exchange these for the pallid couple in the Garden of Eden?

How quickly do we grow accustomed to wonders. I am reminded of the Isaac Asimov story “Nightfall,” about the planet where the stars were visible only once in a thousand years. So awesome was the sight that it drove men mad. We who can see the stars every night glance up casually at the cosmos and then quickly down again, searching for a Dairy Queen.

Hubble's observations suggested that there was a time, called the big bang, when the universe was infinitesimally small and infinitely dense. Under such conditions all the laws of science, and therefore all ability to predict the future, would break down. If there were events earlier than this time, then they could not affect what happens at the present time. Their existence can be ignored because it would have no observational consequences. One may say that time had a beginning at the big bang, in the sense that earlier times simply would not be defined. It should be emphasized that this beginning in time is very different from those that had been considered previously. In an unchanging universe a beginning in time is something that has to be imposed by some being outside the universe; there is no physical necessity for a beginning. One can imagine that God created the universe at literally any time in the past. On the other hand, if the universe is expanding, there may be physical reasons why there had to be a beginning. One could still imagine that God created the universe at the instant of the big bang, or even afterwards in just such a way as to make it look as though there had been a big bang, but it would be meaningless to suppose that it was created before the big bang. An expanding universe does not preclude a creator, but it does place limits on when he might have carried out his job!

Humanity is cutting down its forests, apparently oblivious to the fact that we may not be able to live without them.

I accepted the Copernican position several years ago and discovered from thence the causes of many natural effects which are doubtless inexplicable by the current theories. I have written up many reasons and refutations on the subject, but I have not dared until now to bring them into the open, being warned by the fortunes of Copernicus himself, our master, who procured for himself immortal fame among a few but stepped down among the great crowd (for this is how foolish people are to be numbered), only to be derided and dishonoured. I would dare publish my thoughts if there were many like you; but since there are not, I shall forbear.

I am not a lover of lawns; … the least interesting adjuncts of the country-house. … Rather would I see daisies in their thousands, ground ivy, hawkweed, and even the hated plantain with tall stems, and dandelions with splendid flowers and fairy down, than the too-well-tended lawn.

I am not merely satisfied in making money for myself, for I am endeavoring to provide employment for hundreds of women of my race. ... I want to say to every Negro woman present, don't sit down and wait for the opportunities to come. Get up and make them!

I became expert at dissecting crayfish. At one point I had a crayfish claw mounted on an apparatus in such a way that I could operate the individual nerves. I could get the several-jointed claw to reach down and pick up a pencil and wave it around. I am not sure that what I was doing had much scientific value, although I did learn which nerve fiber had to be excited to inhibit the effects of another fiber so that the claw would open. And it did get me interested in robotic instrumentation, something that I have now returned to. I am trying to build better micromanipulators for surgery and the like.

I called it ignose, not knowing which carbohydrate it was. This name was turned down by my editor. 'God-nose' was not more successful, so in the end 'hexuronic acid' was agreed upon. To-day the substance is called 'ascorbic acid' and I will use this name.

I confess that Fermat’s Theorem as an isolated proposition has very little interest for me, because I could easily lay down a multitude of such propositions, which one could neither prove nor dispose of.

I could not help laughing at the ease with which he explained his process of deduction. “When I hear you give your reasons,” I remarked, “the thing always appears to me to be so ridiculously simple that I could easily do it myself, though at each successive instance of your reasoning I am baffled, until you explain your process. And yet I believe that my eyes are as good as yours.”
“Quite so,” he answered, lighting a cigarette, and throwing himself down into an arm-chair. “You see, but you do not observe. The distinction is clear. For example, you have frequently seen the steps which lead up from the hall to this room.”
“Frequently.”
“How often?”
“'Well, some hundreds of times.”
“Then how many are there?”
“How many! I don't know.”
“Quite so! You have not observed. And yet you have seen. That is just my point. Now, I know that there are seventeen steps, because I have both seen and observed.”

I do hate sums. There is no greater mistake than to call arithmetic an exact science. There are permutations and aberrations discernible to minds entirely noble like mine; subtle variations which ordinary accountants fail to discover; hidden laws of number which it requires a mind like mine to perceive. For instance, if you add a sum from the bottom up, and then from the top down, the result is always different. Again if you multiply a number by another number before you have had your tea, and then again after, the product will be different. It is also remarkable that the Post-tea product is more likely to agree with other people’s calculations than the Pre-tea result.