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Home > Category Index for Science Quotations > Category Index I > Category: Insulin

Insulin Quotes (8 quotes)

Again and again, often in the busiest phases of the insulin investigations, he [Frederick Banting] found time to set a fracture or perform a surgical operation on one of his army comrades or on some patient who was in need.
In 'Obituary: Sir Frederick Banting', Science (14 Mar 1941), N.S. 93, No. 2411, 248.
Science quotes on:  |  Army (22)  |  Sir Frederick Grant Banting (10)  |  Comrade (3)  |  Fracture (4)  |  Investigation (123)  |  Operation (96)  |  Patient (116)  |  Surgery (39)

Diabetus. Ligate pancreatic ducts of dog. Keep dogs alive till acini degenerate leaving Islets. Try to isolate the internal secretion of these to try to relieve glycosurea.
His first inspiration for his future research, while preparing a lecture on the pancreas, and recorded in his notebook. Entry, dated 31 October 1920, in Notebook held by Toronto Academy of Medicine. As quoted in Michael Bliss, The Discovery of Insulin (1982, 1992), 53.
Science quotes on:  |  Pancreas (3)

I used to say the evening that I developed the first x-ray photograph I took of insulin in 1935 was the most exciting moment of my life. But the Saturday afternoon in late July 1969, when we realized that the insulin electron density map was interpretable, runs that moment very close.
'X-rays and the Structure of Insulin', British Medical Journal (1971), 4, 449.
Science quotes on:  |  X-ray Crystallography (11)

In describing a protein it is now common to distinguish the primary, secondary and tertiary structures. The primary structure is simply the order, or sequence, of the amino-acid residues along the polypeptide chains. This was first determined by Sanger using chemical techniques for the protein insulin, and has since been elucidated for a number of peptides and, in part, for one or two other small proteins. The secondary structure is the type of folding, coiling or puckering adopted by the polypeptide chain: the a-helix structure and the pleated sheet are examples. Secondary structure has been assigned in broad outline to a number of librous proteins such as silk, keratin and collagen; but we are ignorant of the nature of the secondary structure of any globular protein. True, there is suggestive evidence, though as yet no proof, that a-helices occur in globular proteins, to an extent which is difficult to gauge quantitatively in any particular case. The tertiary structure is the way in which the folded or coiled polypeptide chains are disposed to form the protein molecule as a three-dimensional object, in space. The chemical and physical properties of a protein cannot be fully interpreted until all three levels of structure are understood, for these properties depend on the spatial relationships between the amino-acids, and these in turn depend on the tertiary and secondary structures as much as on the primary. Only X-ray diffraction methods seem capable, even in principle, of unravelling the tertiary and secondary structures.
Co-author with G. Bodo, H. M. Dintzis, R. G. Parrish, H. Wyckoff, and D. C. Phillips
'A Three-Dimensional Model of the Myoglobin Molecule Obtained by X-ray Analysis', Nature (1958) 181, 662.
Science quotes on:  |  Amino Acid (11)  |  Helix (8)  |  Polypeptide (2)  |  Protein (43)  |  Frederick Sanger (6)  |  Silk (5)  |  Structure (191)  |  X-ray Diffraction (2)

Insulin is not a cure for diabetes; it is a treatment. It enables the diabetic to burn sufficient carbohydrates, so that proteins and fats may be added to the diet in sufficient quantities to provide energy for the economic burdens of life.
'Diabetes and Insulin', Nobel Lecture, 15 September 1925. In Nobel Lectures: Physiology or Medicine, 1922-1941 (1965), 68.
Science quotes on:  |  Diabetes (4)  |  Therapy (10)

Intravenous injections of extract from dog's pancreas, removed from seven to ten weeks after ligation of the ducts, invariably exercises a reducing influence upon the percentage sugar of the blood and the amount of sugar excreted in the urine ... the extent and duration of the reduction varies directly with the amount of extract injected.
Frederick Grant Banting and Charles Herbert Best, 'The Internal Secretion of the Pancreas', Journal of Laboratory and Clinical Medicine, 1922, 7, 251-266.
Science quotes on:  |  Blood (95)  |  Injection (7)  |  Pancreas (3)

Science tries to answer the question: ‘How?’ How do cells act in the body? How do you design an airplane that will fly faster than sound? How is a molecule of insulin constructed? Religion, by contrast, tries to answer the question: ‘Why?’ Why was man created? Why ought I to tell the truth? Why must there be sorrow or pain or death? Science attempts to analyze how things and people and animals behave; it has no concern whether this behavior is good or bad, is purposeful or not. But religion is precisely the quest for such answers: whether an act is right or wrong, good or bad, and why.
Science and Imagination, ch. 4, Basic Books (1967).
Science quotes on:  |  Act (80)  |  Airplane (32)  |  Analyze (3)  |  Animal (309)  |  Answer (201)  |  Attempt (94)  |  Bad (78)  |  Behave (13)  |  Behavior (49)  |  Body (193)  |  Cell (125)  |  Concern (76)  |  Construct (25)  |  Contrast (16)  |  Create (98)  |  Death (270)  |  Design (92)  |  Fast (24)  |  Fly (65)  |  Good (228)  |  Molecule (125)  |  Pain (82)  |  People (269)  |  Precisely (11)  |  Quest (24)  |  Question (315)  |  Religion (210)  |  Right (144)  |  Science (1699)  |  Sorrow (8)  |  Sound (59)  |  Tell (67)  |  Truth (750)  |  Try (103)  |  Wrong (116)

The situation with regard to insulin is particularly clear. In many parts of the world diabetic children still die from lack of this hormone. ... [T]hose of us who search for new biological facts and for new and better therapeutic weapons should appreciate that one of the central problems of the world is the more equitable distribution and use of the medical and nutritional advances which have already been established. The observations which I have recently made in parts of Africa and South America have brought this fact very forcible to my attention.
'Studies on Diabetes and Cirrhosis', Proceedings, American Philosophical Society (1952) 96, No. 1, 29.
Science quotes on:  |  Advance (123)  |  Africa (15)  |  Attention (76)  |  Child (189)  |  Death (270)  |  Diabetes (4)  |  Distribution (21)  |  Equity (2)  |  Hormone (7)  |  Lack (52)  |  Medicine (322)  |  Nutrition (15)  |  Observation (418)  |  Problem (362)  |  Research (517)  |  Situation (41)  |  South America (4)  |  Therapy (10)  |  World (667)


Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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