...after my first feeling of revulsion had passed, I spent three of the most entertaining and instructive weeks of my life studying the fascinating molds which appeared one by one on the slowly disintegrating mass of horse-dung. Microscopic molds are both very beautiful and absorbingly interesting. The rapid growth of their spores, the way they live on each other, the manner in which the different forms come and go, is so amazing and varied that I believe a man could spend his life and not exhaust the forms or problems contained in one plate of manure.

...the genes almost always accurately reproduce. If they don't, you get one of the following results: One, monsters—that is, grossly malformed babies resulting from genetic mistakes. Years ago most monsters died, but now many can be saved. This has made possible the National Football League.

...the study of butterflies—creatures selected as the types of airiness and frivolity—instead of being despised, will some day be valued as one of the most important branches of Biological science.

...they have never affirm'd any thing, concerning the Cause, till the Trial was past: whereas, to do it before, is a most venomous thing in the making of Sciences; for whoever has fix'd on his Cause, before he experimented; can hardly avoid fitting his Experiment to his Observations, to his own Cause, which he had before imagin'd; rather than the Cause to the Truth of the Experiment itself.
Referring to experiments of the Aristotelian mode, whereby a preconceived truth would be illustrated merely to convince people of the validity of the original thought.

...those experiments be not only esteemed which have an immediate and present use, but those principally which are of most universal consequence for invention of other experiments, and those which give more light to the invention of causes; for the invention of the mariner's needle, which giveth the direction, is of no less benefit for navigation than the invention of the sails, which give the motion.

1839—The fermentation satire
THE MYSTERY OF ALCOHOLIC FERMENTATION RESOLVED
(Preliminary Report by Letter) Schwindler
I am about to develop a new theory of wine fermentation … Depending on the weight, these seeds carry fermentation to completion somewhat less than as in the beginning, which is understandable … I shall develop a new theory of wine fermentation [showing] what simple means Nature employs in creating the most amazing phenomena. I owe it to the use of an excellent microscope designed by Pistorius.
When brewer’s yeast is mixed with water the microscope reveals that the yeast dissolves into endless small balls, which are scarcely 1/800th of a line in diameter … If these small balls are placed in sugar water, it can be seen that they consist of the eggs of animals. As they expand, they burst, and from them develop small creatures that multiply with unbelievable rapidity in a most unheard of way. The form of these animals differs from all of the 600 types described up until now. They possess the shape of a Beinsdorff still (without the cooling apparatus). The head of the tube is a sort of proboscis, the inside of which is filled with fine bristles 1/2000th of a line long. Teeth and eyes are not discernible; however, a stomach, intestinal canal, anus (a rose red dot), and organs for secretion of urine are plainly discernible. From the moment they are released from the egg one can see these animals swallow the sugar from the solution and pass it to the stomach. It is digested immediately, a process recognized easily by the resultant evacuation of excrements. In a word, these infusors eat sugar, evacuate ethyl alcohol from the intestinal canal, and carbon dioxide from the urinary organs. The bladder, in the filled state, has the form of a champagne bottle; when empty, it is a small button … As soon as the animals find no more sugar present, they eat each other up, which occurs through a peculiar manipulation; everything is digested down to the eggs which pass unchanged through the intestinal canal. Finally, one again fermentable yeast, namely the seed of the animals, which remain over.

A stands for atom; it is so small No one has ever seen it at all.
B stands for bomb; the bombs are much bigger,
So, brother, do not be too fast on the trigger.
H has become a most ominous letter.
It means something bigger if not something better.

But how shall we this union well expresse?
Naught tyes the soule: her subtiltie is such
She moves the bodie, which she doth possesse.
Yet no part toucheth, but by Vertue's touch.
Then dwels she not therein as in a tent;
Nor as a pilot in his Ship doth sit;
Nor as the spider in his web is pent;
Nor as the Waxe retaines the print in it;
Nor as a Vessell water doth containe;
Nor as one Liquor in another shed;
Nor as the heate dath in the fire remaine;
Nor as a voice throughout the ayre is spred;
But as the faire and cheerfull morning light,
Doth here, and there, her silver beames impart,
And in an instant doth her selfe unite
To the transparent Aire, in all, and part:
Still resting whole, when blowes the Aire devide;
Abiding pure, when th' Aire is most corrupted;
Throughout the Aire her beames dispersing wide,
And when the Aire is tost, not interrupted:
So doth the piercing Soule the body fill;
Being all in all, and all in part diffus'd;
Indivisible, incorruptible still,
Not forc't, encountred, troubled or confus'd.
And as the Sunne above the light doth bring,
Tough we behold it in the Aire below;
So from th'eternall light the Soule doth spring,
Though in the Bodie she her powers do show.

Combien de gens se font abstraits pour paraître profonds! La plupart des termes abstraits sont des ombres qui cachent des vides.
How many people become abstract in order to appear profound! Most abstract terms are shadows that conceal a void.

Dilbert: I’m obsessed with inventing a perpetual motion machine. Most scientists think it's impossible, but I have something they don’t.
Dogbert: A lot of spare time?
Dilbert: Exactly.

Eine brennendste Zeitfrage allerdings! Es brennt in allen Ecken und Enden der ethnologischen Welt, brennt hell, lichterloh, in vollster Brunst, es brennt ringsum, Gross Feuer! und Niemand regt eine Hand.
A most burning question of time, though. It burns in every nook and cranny of the ethnological world, burning, bright, brightly, in the fullest blaze, and it burns all around, huge fire! and no one lifts a hand.
[Expressing his desperation over the loss of the cultural memory of ethnic traditions as so many cultures were no longer living in isolation.]

Engineering, too, owes its most useful materials to the achievements of chemists in identifying, separating, and transforming materials: structural steel for the framework of bridges and buildings, portland cement for roadways and aqueducts, pure copper for the electrical industries, aluminum alloys for automobiles and airplanes, porcelain for spark plugs and electrical insulators. The triumphs of engineering skill rest on a chemical foundation.

I. Animals have an electricity peculiar to themselves to which the name animal electricity is given.
II. The organs in which animal electricity acts above all others, and by which it is distributed throughout the whole body, are the nerves, and the most important organ of secretion is the brain.

In primis, hominis est propria VERI inquisitio atque investigato. Itaque cum sumus negotiis necessariis, curisque vacui, tum avemus aliquid videre, audire, ac dicere, cognitionemque rerum, aut occultarum aut admirabilium, ad benè beatéque vivendum necessariam ducimus; —ex quo intelligitur, quod VERUM, simplex, sincerumque sit, id esse naturæ hominis aptissimum. Huic veri videndi cupiditati adjuncta est appetitio quædam principatûs, ut nemini parere animus benè a naturâ informatus velit, nisi præcipienti, aut docenti, aut utilitatis causâ justè et legitimè imperanti: ex quo animi magnitudo existit, et humanarum rerum contemtio.
Before all other things, man is distinguished by his pursuit and investigation of TRUTH. And hence, when free from needful business and cares, we delight to see, to hear, and to communicate, and consider a knowledge of many admirable and abstruse things necessary to the good conduct and happiness of our lives: whence it is clear that whatsoever is TRUE, simple, and direct, the same is most congenial to our nature as men. Closely allied with this earnest longing to see and know the truth, is a kind of dignified and princely sentiment which forbids a mind, naturally well constituted, to submit its faculties to any but those who announce it in precept or in doctrine, or to yield obedience to any orders but such as are at once just, lawful, and founded on utility. From this source spring greatness of mind and contempt of worldly advantages and troubles.

La chaleur pénètre, comme la gravité, toutes les substances de l’univers, ses rayons occupent toutes les parties de l’espace. Le but de notre ouvrage est d’exposer les lois mathématiques que suit cet élément. Cette théorie formera désormais une des branches les plus importantes de la physique générale.
Heat, like gravity, penetrates every substance of the universe, its rays occupy all parts of space. The object of our work is to set forth the mathematical laws which this element obeys. The theory of heat will hereafter form one of the most important branches of general physics.

La santé est le trésor le plus précieux et le plus facile à perdre; c'est cependant le plus mal gardé.
Health is the most valuable and most easily lost treasure; yet it is the most poorly kept.

Les médecins les plus savans en théorie sont rarement les plus habile practiciens.
The doctors most learned in theory are seldom the most skilled practitioners.

Prospero: Hast thou, spirit,
Performed, to point, the tempest that I bade thee?
Ariel: To every article.
I boarded the king’s ship. Now on the beak,
Now in the waist, the deck, in every cabin,
I flamed amazement.
Sometime I’d divide
And burn in many places; on the topmast,
The yards, and bowsprit would I flame distinctly,
Then meet and join. Jove’s lightnings, the precursors
O’ th’ dreadful thunderclaps, more momentary
And sight-outrunning were not. The fire and cracks
Of sulphurous roaring the most mighty Neptune
Seem to besiege, and make his bold waves tremble;
Yea, his dread trident shake.

Question: If you walk on a dry path between two walls a few feet apart, you hear a musical note or “ring” at each footstep. Whence comes this?
Answer: This is similar to phosphorescent paint. Once any sound gets between two parallel reflectors or walls, it bounds from one to the other and never stops for a long time. Hence it is persistent, and when you walk between the walls you hear the sounds made by those who walked there before you. By following a muffin man down the passage within a short time you can hear most distinctly a musical note, or, as it is more properly termed in the question, a “ring” at every (other) step.

Question: If you were to pour a pound of molten lead and a pound of molten iron, each at the temperature of its melting point, upon two blocks of ice, which would melt the most ice, and why?
Answer: This question relates to diathermancy. Iron is said to be a diathermanous body (from dia, through, and thermo, I heat), meaning that it gets heated through and through, and accordingly contains a large quantity of real heat. Lead is said to be an athermanous body (from a, privative, and thermo, I heat), meaning that it gets heated secretly or in a latent manner. Hence the answer to this question depends on which will get the best of it, the real heat of the iron or the latent heat of the lead. Probably the iron will smite furthest into the ice, as molten iron is white and glowing, while melted lead is dull.

Surtout l’astronomie et l’anatomie sont les deux sciences qui nous offrent le plus sensiblement deux grands caractères du Créateur; l’une, son immensité, par les distances, la grandeur, et le nombre des corps célestes; l’autre, son intelligence infinie, par la méchanique des animaux.
Above all, astronomy and anatomy are the two sciences which present to our minds most significantly the two grand characteristics of the Creator; the one, His immensity, by the distances, size, and number of the heavenly bodies; the other, His infinite intelligence, by the mechanism of animate beings.

That the general characters of the big group to which the embryo belongs appear in development earlier than the special characters. In agreement with this is the fact that the vesicular form is the most general form of all; for what is common in a greater degree to all animals than the opposition of an internal and an external surface?
The less general structural relations are formed after the more general, and so on until the most special appear.
The embryo of any given form, instead of passing through the state of other definite forms, on the contrary separates itself from them.
Fundamentally the embryo of a higher animal form never resembles the adult of another animal form, but only its embryo.

Tout homme qui reçoit une éducation libérale compte aujourd'hui la chimie parmi les objets les plus indispensables de ses études.
Everyone who receives a liberal education today counts chemistry among the most essential parts of his studies.

Trimming consists of clipping off little bits here and there from those observations which differ most in excess from the mean, and in sticking them onto those which are too small; a species of 'equitable adjustment,' as a radical would term it, which cannot be admitted in science.

[Describing the effects of over-indulgence in wine:]
But most too passive, when the blood runs low
Too weakly indolent to strive with pain,
And bravely by resisting conquer fate,
Try Circe's arts; and in the tempting bowl
Of poisoned nectar sweet oblivion swill.
Struck by the powerful charm, the gloom dissolves
In empty air; Elysium opens round,
A pleasing frenzy buoys the lightened soul,
And sanguine hopes dispel your fleeting care;
And what was difficult, and what was dire,
Yields to your prowess and superior stars:
The happiest you of all that e'er were mad,
Or are, or shall be, could this folly last.
But soon your heaven is gone: a heavier gloom
Shuts o'er your head; and, as the thundering stream,
Swollen o'er its banks with sudden mountain rain,
Sinks from its tumult to a silent brook,
So, when the frantic raptures in your breast
Subside, you languish into mortal man;
You sleep, and waking find yourself undone,
For, prodigal of life, in one rash night
You lavished more than might support three days.
A heavy morning comes; your cares return
With tenfold rage. An anxious stomach well
May be endured; so may the throbbing head;
But such a dim delirium, such a dream,
Involves you; such a dastardly despair
Unmans your soul, as maddening Pentheus felt,
When, baited round Citheron's cruel sides,
He saw two suns, and double Thebes ascend.

[Question: What do you think was the most important physics idea to emerge this year?]
We won't know for a few years.

CALPURNIA: When beggars die there are no comets seen;
The heavens themselves blaze forth the death of princes.
CAESAR: Cowards die many times before their deaths;
The valiant never taste of death but once.
Of all the wonders that I have yet heard,
It seems to me most strange that men should fear,
Seeing that death, a necessary end,
Will come when it will come.

CLAUDIO: Death is a fearful thing.
ISABELLA: And shamed life a hateful.
CLAUDIO: Ay, but to die, and go we know not where;
To lie in cold obstruction, and to rot;
This sensible warm motion to become
A kneaded clod; and the delighted spirit
To bathe in fiery floods, or to reside
In thrilling region of thick-ribbed ice;
To be imprisioned in the viewless winds,
And blown with restless violence round about
The pendant world; or to be worst than worst
Of those lawless and incertain thought
Imagine howling—'tis too horrible!
The weariest and most loathed worldly life
That age, ache, penury, and imprisionment
Can lay on nature is a paradise
To what we fear of death.

A calculating engine is one of the most intricate forms of mechanism, a telegraph key one of the simplest. But compare their value.

A child’s world is fresh and new and beautiful, full of wonder and excitement. It is our misfortune that for most of us that clear-eyed vision, that true instinct for what is beautiful and awe-inspiring, is dimmed and even lost before we reach adulthood.

A circumstance which influenced my whole career more than any other … was my friendship with Professor Henslow … a man who knew every branch of science…. During the latter half of my time at Cambridge [I] took long walks with him on most days; so that I was called by some of the dons “the man who walks with Henslow.”

A closer look at the course followed by developing theory reveals for a start that it is by no means as continuous as one might expect, but full of breaks and at least apparently not along the shortest logical path. Certain methods often afforded the most handsome results only the other day, and many might well have thought that the development of science to infinity would consist in no more than their constant application. Instead, on the contrary, they suddenly reveal themselves as exhausted and the attempt is made to find other quite disparate methods. In that event there may develop a struggle between the followers of the old methods and those of the newer ones. The former's point of view will be termed by their opponents as out-dated and outworn, while its holders in turn belittle the innovators as corrupters of true classical science.

A discovery in science, or a new theory, even when it appears most unitary and most all-embracing, deals with some immediate element of novelty or paradox within the framework of far vaster, unanalysed, unarticulated reserves of knowledge, experience, faith, and presupposition. Our progress is narrow; it takes a vast world unchallenged and for granted. This is one reason why, however great the novelty or scope of new discovery, we neither can, nor need, rebuild the house of the mind very rapidly. This is one reason why science, for all its revolutions, is conservative. This is why we will have to accept the fact that no one of us really will ever know very much. This is why we shall have to find comfort in the fact that, taken together, we know more and more.

A fair number of people who go on to major in astronomy have decided on it certainly by the time they leave junior high, if not during junior high. I think it’s somewhat unusual that way. I think most children pick their field quite a bit later, but astronomy seems to catch early, and if it does, it sticks.

A few days afterwards, I went to him [the same actuary referred to in another quote] and very gravely told him that I had discovered the law of human mortality in the Carlisle Table, of which he thought very highly. I told him that the law was involved in this circumstance. Take the table of the expectation of life, choose any age, take its expectation and make the nearest integer a new age, do the same with that, and so on; begin at what age you like, you are sure to end at the place where the age past is equal, or most nearly equal, to the expectation to come. “You don’t mean that this always happens?”—“Try it.” He did try, again and again; and found it as I said. “This is, indeed, a curious thing; this is a discovery!” I might have sent him about trumpeting the law of life: but I contented myself with informing him that the same thing would happen with any table whatsoever in which the first column goes up and the second goes down.

A field is the most just possession for men. For what nature requires it carefully bears: barley, oil, wine, figs, honey. Silver-plate and purple will do for the tragedians, not for life.

A fossil hunter needs sharp eyes and a keen search image, a mental template that subconsciously evaluates everything he sees in his search for telltale clues. A kind of mental radar works even if he isn’t concentrating hard. A fossil mollusk expert has a mollusk search image. A fossil antelope expert has an antelope search image. … Yet even when one has a good internal radar, the search is incredibly more difficult than it sounds. Not only are fossils often the same color as the rocks among which they are found, so they blend in with the background; they are also usually broken into odd-shaped fragments. … In our business, we don’t expect to find a whole skull lying on the surface staring up at us. The typical find is a small piece of petrified bone. The fossil hunter’s search therefore has to have an infinite number of dimensions, matching every conceivable angle of every shape of fragment of every bone on the human body.
Describing the skill of his co-worker, Kamoya Kimeu, who discovered the Turkana Boy, the most complete specimen of Homo erectus, on a slope covered with black lava pebbles.

A good ornithologist should be able to distinguish birds by their air as well as by their colors and shape; on the ground as well as on the wing, and in the bush as well as in the hand. For, though it must not be said that every species of birds has a manner peculiar to itself, yet there is somewhat, in most genera at least, that at first sight discriminates them and enables a judicious observer to pronounce upon them with some certainty.

A government, at bottom, is nothing more than a gang of men, and as a practical matter most of them are inferior men ... Government is actually the worst failure of civilized man. There has never been a really good one, and even those that are most tolerable are arbitrary, cruel, grasping and unintelligent. Indeed, it would not be far wrong to describe the best as the common enemy of all decent citizens.

A habit of basing convictions upon evidence, and of giving to them only that degree or certainty which the evidence warrants, would, if it became general, cure most of the ills from which the world suffers.

A hot topic of late, expressed most notably in Bernie Siegel’s best-selling books, has emphasized the role of positive attitude in combating such serious diseases as cancer. From the depths of my skeptical and rationalist soul, I ask the Lord to protect me from California touchie-feeliedom.

A huge net is being dragged across the sea floor, destroying everything in its path. Ahead of it bloom undersea forests and their hundreds and thousands of living creatures, both plant and animal; behind it is a desert. The net is pulled to the surface and most of the dead and dying life forms in it are thrown out. A few marketable species are retained. [Trawling] is like taking a front-end loader and scraping up your entire front garden and shredding it, keeping a few pebbles, and dumping the rest of it down the drain.

A marine protozoan is an aqueous salty system in an aqueous salty medium, but a man is an aqueous salty system in a medium in which there is but little water and most of that poor in salts.

A mathematical point is the most indivisble and unique thing which art can present.

A mere inference or theory must give way to a truth revealed; but a scientific truth must be maintained, however contradictory it may appear to the most cherished doctrines of religion.

A million years is a short time—the shortest worth messing with for most problems. You begin tuning your mind to a time scale that is the planet’s time scale. For me, it is almost unconscious now and is a kind of companionship with the earth.

A most vile face! and yet she spends me forty pound a year in Mercury and Hogs Bones. All her teeth were made in the Black-Fryars, both her Eyebrows i’ the Strand, and her Hair in Silver-street. Every part of Town owns a Piece of her.

A multidisciplinary study group ... estimated that it would be 1980 before developments in artificial intelligence make it possible for machines alone to do much thinking or problem solving of military significance. That would leave, say, five years to develop man-computer symbiosis and 15 years to use it. The 15 may be 10 or 500, but those years should be intellectually the most creative and exciting in the history of mankind.

A multitude of words doth rather obscure than illustrate, they being a burden to the memory, and the first apt to be forgotten, before we come to the last. So that he that uses many words for the explaining of any subject, doth, like the cuttle-fish, hide himself, for the most part, in his own ink.

A Native American elder once described his own inner struggles in this manner: Inside of me there are two dogs. One of the dogs is mean and evil. The other dog is good. The mean dog fights the good dog all the time. When asked which dog wins, he reflected for a moment and replied, The one I feed the most.

A neurotic person can be most simply described as someone who, while he was growing up, learned ways of behaving that are self-defeating in his society.

A noteworthy and often-remarked similarity exists between the facts and methods of geology and those of linguistic study. The science of language is, as it were, the geology of the most modern period, the Age of the Man, having for its task to construct the history of development of the earth and its inhabitants from the time when the proper geological record remains silent … The remains of ancient speech are like strata deposited in bygone ages, telling of the forms of life then existing, and of the circumstances which determined or affected them; while words are as rolled pebbles, relics of yet more ancient formations, or as fossils, whose grade indicates the progress of organic life, and whose resemblances and relations show the correspondence or sequence of the different strata; while, everywhere, extensive denudation has marred the completeness of the record, and rendered impossible a detailed exhibition of the whole course of development.

A parable: A man was examining the construction of a cathedral. He asked a stone mason what he was doing chipping the stones, and the mason replied, “I am making stones.” He asked a stone carver what he was doing. “I am carving a gargoyle.” And so it went, each person said in detail what they were doing. Finally he came to an old woman who was sweeping the ground. She said. “I am helping build a cathedral.”
...Most of the time each person is immersed in the details of one special part of the whole and does not think of how what they are doing relates to the larger picture.
[For example, in education, a teacher might say in the next class he was going to “explain Young's modulus and how to measure it,” rather than, “I am going to educate the students and prepare them for their future careers.”]

A pawn is the most important piece on the chessboard—to a pawn.

A peacetime draft is the most un-American thing I know.

A person filled with gumption doesn’t sit about stewing about things. He’s at the front of the train of his own awareness, watching to see what’s up the track and meeting it when it comes. That’s gumption. If you’re going to repair a motorcycle, an adequate supply of gumption is the first and most important tool. If you haven’t got that you might as well gather up all the other tools and put them away, because they won’t do you any good.

A physician’s subject of study is necessarily the patient, and his first field for observation is the hospital. But if clinical observation teaches him to know the form and course of diseases, it cannot suffice to make him understand their nature; to this end he must penetrate into the body to find which of the internal parts are injured in their functions. That is why dissection of cadavers and microscopic study of diseases were soon added to clinical observation. But to-day these various methods no longer suffice; we must push investigation further and, in analyzing the elementary phenomena of organic bodies, must compare normal with abnormal states. We showed elsewhere how incapable is anatomy alone to take account of vital phenenoma, and we saw that we must add study of all physico-chemical conditions which contribute necessary elements to normal or pathological manifestations of life. This simple suggestion already makes us feel that the laboratory of a physiologist-physician must be the most complicated of all laboratories, because he has to experiment with phenomena of life which are the most complex of all natural phenomena.

A railroad may have to be carried over a gorge or arroya. Obviously it does not need an Engineer to point out that this may be done by filling the chasm with earth, but only a Bridge Engineer is competent to determine whether it is cheaper to do this or to bridge it, and to design the bridge which will safely and most cheaply serve.

A science in its infancy is the least satisfactory, and, at the same time, the most profitable theme for a general description.

A vast technology has been developed to prevent, reduce, or terminate exhausting labor and physical damage. It is now dedicated to the production of the most trivial conveniences and comfort.

A vision of the whole of life!. Could any human undertaking be ... more grandiose? This attempt stands without rival as the most audacious enterprise in which the mind of man has ever engaged ... Here is man, surrounded by the vastness of a universe in which he is only a tiny and perhaps insignificant part—and he wants to understand it.

A wonder then it must needs be,—that there should be any Man found so stupid and forsaken of reason as to persuade himself, that this most beautiful and adorned world was or could be produced by the fortuitous concourse of atoms.

A … difference between most system-building in the social sciences and systems of thought and classification of the natural sciences is to be seen in their evolution. In the natural sciences both theories and descriptive systems grow by adaptation to the increasing knowledge and experience of the scientists. In the social sciences, systems often issue fully formed from the mind of one man. Then they may be much discussed if they attract attention, but progressive adaptive modification as a result of the concerted efforts of great numbers of men is rare.

A “pacifist male” is a contradiction in terms. Most self-described “pacifists” are not pacific; they simply assume false colors. When the wind changes, they hoist the Jolly Roger.

About eight days ago I discovered that sulfur in burning, far from losing weight, on the contrary, gains it; it is the same with phosphorus; this increase of weight arises from a prodigious quantity of air that is fixed during combustion and combines with the vapors. This discovery, which I have established by experiments, that I regard as decisive, has led me to think that what is observed in the combustion of sulfur and phosphorus may well take place in the case of all substances that gain in weight by combustion and calcination; and I am persuaded that the increase in weight of metallic calxes is due to the same cause... This discovery seems to me one of the most interesting that has been made since Stahl and since it is difficult not to disclose something inadvertently in conversation with friends that could lead to the truth I have thought it necessary to make the present deposit to the Secretary of the Academy to await the time I make my experiments public.

Abstract as it is, science is but an outgrowth of life. That is what the teacher must continually keep in mind. … Let him explain … science is not a dead system—the excretion of a monstrous pedantism—but really one of the most vigorous and exuberant phases of human life.

Abstruse mathematical researches … are … often abused for having no obvious physical application. The fact is that the most useful parts of science have been investigated for the sake of truth, and not for their usefulness. A new branch of mathematics, which has sprung up in the last twenty years, was denounced by the Astronomer Royal before the University of Cambridge as doomed to be forgotten, on account of its uselessness. Now it turns out that the reason why we cannot go further in our investigations of molecular action is that we do not know enough of this branch of mathematics.

After Gibbs, one the most distinguished [American scientists] was Langley, of the Smithsonian. … He had the physicist’s heinous fault of professing to know nothing between flashes of intense perception. … Rigidly denying himself the amusement of philosophy, which consists chiefly in suggesting unintelligible answers to insoluble problems, and liked to wander past them in a courteous temper, even bowing to them distantly as though recognizing their existence, while doubting their respectability.

Again and again in reading even his [William Thomson] most abstract writings one is struck by the tenacity with which physical ideas control in him the mathematical form in which he expressed them. An instance of this is afforded by … an example of a mathematical result that is, in his own words, “not instantly obvious from the analytical form of my solution, but which we immediately see must be the case by thinking of the physical meaning of the result.”

Alchymy, or Chymistry, is …
An Art which good men bate, and most men blame,
Which her admirers practice to their shame,
Whose plain Impostures, easie to perceive,
Not onely others, but themselves deceive.

All admit that the mountains of the globe are situated mostly along the border regions of the continents (taking these regions as 300 to 1000 miles or more in width), and that over these same areas the sedimentary deposits have, as a general thing, their greatest thickness. At first thought, it would seem almost incredible that the upliftings of mountains, whatever their mode of origin, should have taken place just where the earth’s crust, through these sedimentary accumulations, was the thickest, and where, therefore, there was the greatest weight to be lifted. … Earthquakes show that even now, in this last of the geological ages, the same border regions of the continents, although daily thickening from the sediments borne to the ocean by rivers, are the areas of the greatest and most frequent movements of the earth’s crust. (1866)
[Thus, the facts were known long ago; the explanation by tectonic activity came many decades later.]

All fossil anthropoids found hitherto have been known only from mandibular or maxillary fragments, so far as crania are concerned, and so the general appearance of the types they represented had been unknown; consequently, a condition of affairs where virtually the whole face and lower jaw, replete with teeth, together with the major portion of the brain pattern, have been preserved, constitutes a specimen of unusual value in fossil anthropoid discovery. Here, as in Homo rhodesiensis, Southern Africa has provided documents of higher primate evolution that are amongst the most complete extant. Apart from this evidential completeness, the specimen is of importance because it exhibits an extinct race of apes intermediate between living anthropoids and man ... Whether our present fossil is to be correlated with the discoveries made in India is not yet apparent; that question can only be solved by a careful comparison of the permanent molar teeth from both localities. It is obvious, meanwhile, that it represents a fossil group distinctly advanced beyond living anthropoids in those two dominantly human characters of facial and dental recession on one hand, and improved quality of the brain on the other. Unlike Pithecanthropus, it does not represent an ape-like man, a caricature of precocious hominid failure, but a creature well advanced beyond modern anthropoids in just those characters, facial and cerebral, which are to be anticipated in an extinct link between man and his simian ancestor. At the same time, it is equally evident that a creature with anthropoid brain capacity and lacking the distinctive, localised temporal expansions which appear to be concomitant with and necessary to articulate man, is no true man. It is therefore logically regarded as a man-like ape. I propose tentatively, then, that a new family of Homo-simidæ be created for the reception of the group of individuals which it represents, and that the first known species of the group be designated Australopithecus africanus, in commemoration, first, of the extreme southern and unexpected horizon of its discovery, and secondly, of the continent in which so many new and important discoveries connected with the early history of man have recently been made, thus vindicating the Darwinian claim that Africa would prove to be the cradle of mankind.

All good intellects have repeated, since Bacon’s time, that there can be no real knowledge but that which is based on observed facts. This is incontestable, in our present advanced stage; but, if we look back to the primitive stage of human knowledge, we shall see that it must have been otherwise then. If it is true that every theory must be based upon observed facts, it is equally true that facts cannot be observed without the guidance of some theory. Without such guidance, our facts would be desultory and fruitless; we could not retain them: for the most part we could not even perceive them.

All historians, even the most scientific, have bias, if in no other sense than the determination not to have any.

All men and women are born, live suffer and die; what distinguishes us one from another is our dreams, whether they be dreams about worldly or unworldly things, and what we do to make them come about... We do not choose to be born. We do not choose our parents. We do not choose our historical epoch, the country of our birth, or the immediate circumstances of our upbringing. We do not, most of us, choose to die; nor do we choose the time and conditions of our death. But within this realm of choicelessness, we do choose how we live.

All Men are liable to Error, and most Men are in many Points, by Passion or Interest, under Temptation to it.

All men seek to be enlightened. Religion is but the most ancient and honorable way in which men have striven to make sense out of God's universe. Scientists seek the lawfulness of events. It is the task of Religion to fit man into this lawfulness.

All men seek to be enlightened. Religion is but the most ancient and honorable way in which men have striven to make sense out of God's universe. Scientists seek the lawfulness of events. It is the task of Religion to fit man into this lawfulness.

All men seek to be enlightened. Religion is but the most ancient and honorable way in which men have striven to make sense out of God's universe. Scientists seek the lawfulness of events. It is the task of Religion to fit man into this lawfulness.

All revolutionary advances in science may consist less of sudden and dramatic revelations than a series of transformations, of which the revolutionary significance may not be seen (except afterwards, by historians) until the last great step. In many cases the full potentiality and force of a most radical step in such a sequence of transformations may not even be manifest to its author.

All that Anatomie can doe is only to shew us the gross and sensible parts of the body, or the vapid and dead juices all which, after the most diligent search, will be noe more able to direct a physician how to cure a disease than how to make a man; for to remedy the defects of a part whose organicall constitution and that texture whereby it operates, he cannot possibly know, is alike hard, as to make a part which he knows not how is made. Now it is certaine and beyond controversy that nature performs all her operations on the body by parts so minute and insensible that I thinke noe body will ever hope or pretend, even by the assistance of glasses or any other intervention, to come to a sight of them, and to tell us what organicall texture or what kinde offerment (for whether it be done by one or both of these ways is yet a question and like to be soe always notwithstanding all the endeavours of the most accurate dissections) separate any part of the juices in any of the viscera, or tell us of what liquors the particles of these juices are, or if this could be donne (which it is never like to be) would it at all contribute to the cure of the diseases of those very parts which we so perfectly knew.

All the inventions and devices ever constructed by the human hand or conceived by the human mind, no matter how delicate, how intricate and complicated, are simple, childish toys compared with that most marvelously wrought mechanism, the human body. Its parts are far more delicate, and their mutual adjustments infinitely more accurate, than are those of the most perfect chronometer ever made.

All the summer long is the swallow a most instructive pattern of unwearied industry and affection; for, from morning to night, while there is a family to be supported, she spends the whole day in skimming close to the ground, and exerting the most sudden turns and quick evolutions. Avenues, and long walks under hedges, and pasture-fields, and mown meadows where cattle graze, are her delight, especially if there are trees interspersed; because in such spots insects most abound. When a fly is taken a smart snap from her bill is heard, resembling the noise at the shutting of a watch case; but the motion of the mandibles are too quick for the eye.

All things are made of atoms—little particles that move around in perpetual motion, attracting each other when they are a little distance apart, but repelling upon being squeezed into one another. In that one sentence ... there is an enormous amount of information about the world.
His suggestion that the most valuable information on scientific knowledge in a single sentence using the fewest words is to state the atomic hypothesis.

All things on the earth are the result of chemical combination. The operation by which the commingling of molecules and the interchange of atoms take place we can imitate in our laboratories; but in nature they proceed by slow degrees, and, in general, in our hands they are distinguished by suddenness of action. In nature chemical power is distributed over a long period of time, and the process of change is scarcely to be observed. By acts we concentrate chemical force, and expend it in producing a change which occupies but a few hours at most.

Also the earth is not spherical, as some have said, although it tends toward sphericity, for the shape of the universe is limited in its parts as well as its movement… . The movement which is more perfect than others is, therefore, circular, and the corporeal form which is the most perfect is the sphere.

Although I was four years at the University [of Wisconsin], I did not take the regular course of studies, but instead picked out what I thought would be most useful to me, particularly chemistry, which opened a new world, mathematics and physics, a little Greek and Latin, botany and and geology. I was far from satisfied with what I had learned, and should have stayed longer.
[Enrolled in Feb 1861, left in 1863 without completing a degree, and began his first botanical foot journey.]

Although the works of the Creator may be in themselves all equally perfect, the animal is, as I see it, the most complete work of nature, and man is her masterpiece.

Although we know nothing of what an atom is, yet we cannot resist forming some idea of a small particle, which represents it to the mind ... there is an immensity of facts which justify us in believing that the atoms of matter are in some way endowed or associated with electrical powers, to which they owe their most striking qualities, and amongst them their mutual chemical affinity.
[Summarizing his investigations in electrolysis.]

Although with the majority of those who study and practice in these capacities [engineers, builders, surveyors, geographers, navigators, hydrographers, astronomers], secondhand acquirements, trite formulas, and appropriate tables are sufficient for ordinary purposes, yet these trite formulas and familiar rules were originally or gradually deduced from the profound investigations of the most gifted minds, from the dawn of science to the present day. … The further developments of the science, with its possible applications to larger purposes of human utility and grander theoretical generalizations, is an achievement reserved for a few of the choicest spirits, touched from time to time by Heaven to these highest issues. The intellectual world is filled with latent and undiscovered truth as the material world is filled with latent electricity.

Aluminum is at once as white as silver, as incorrodible as gold, as tenacious as iron, as fusible as copper, and as light as glass. It is easily worked; it is widely spread in nature, alumina forming the bases of most rocks; it is three times lighter than iron; in short, it seems to have been created expressly to furnish material for our projectile!

Among all highly civilized peoples the golden age of art has always been closely coincident with the golden age of the pure sciences, particularly with mathematics, the most ancient among them.
This coincidence must not be looked upon as accidental, but as natural, due to an inner necessity. Just as art can thrive only when the artist, relieved of the anxieties of existence, can listen to the inspirations of his spirit and follow in their lead, so mathematics, the most ideal of the sciences, will yield its choicest blossoms only when life’s dismal phantom dissolves and fades away, when the striving after naked truth alone predominates, conditions which prevail only in nations while in the prime of their development.

Among all types of sexual activity, masturbation is ... the one in which the female most frequently reaches orgasm.

Among both the Northern and Eastern Hamites are to be found some of the most beautiful types of humanity.

Among natural bodies some have, and some have not, life; and by life we mean the faculties of self-nourishment, self-growth and self-decay. Thus every natural body partaking of life may be regarded as an essential existence; … but then it is an existence only in combination. … And since the organism is such a combination, being possessed of life, it cannot be the Vital Principle. Therefore it follows that the Vital Principle most be an essence, as being the form of a natural body, holding life in potentiality; but essence is a reality (entetechie). The Vital Principle is the original reality of a natural body endowed with potential life; this, however, is to be understood only of a body which may be organized. Thus the parts even of plants are organs, but they are organs that are altogether simple; as the leaf which is the covering of the pericarp, the pericarp of the fruit. If, then, there be any general formula for every kind of Vital Principle, it is—tthe primary reality of an organism.

Among the memoirs of Kirchhoff are some of uncommon beauty. … Can anything be beautiful, where the author has no time for the slightest external embellishment?—But—; it is this very simplicity, the indispensableness of each word, each letter, each little dash, that among all artists raises the mathematician nearest to the World-creator; it establishes a sublimity which is equalled in no other art, something like it exists at most in symphonic music. The Pythagoreans recognized already the similarity between the most subjective and the most objective of the arts.

Ampère was a mathematician of various resources & I think might rather be called excentric [sic] than original. He was as it were always mounted upon a hobby horse of a monstrous character pushing the most remote & distant analogies. This hobby horse was sometimes like that of a child ['s] made of heavy wood, at other times it resembled those [?] shapes [?] used in the theatre [?] & at other times it was like a hypogrif in a pantomime de imagie. He had a sort of faith in animal magnetism & has published some refined & ingenious memoirs to prove the identity of electricity & magnetism but even in these views he is rather as I said before excentric than original. He has always appeared to me to possess a very discursive imagination & but little accuracy of observation or acuteness of research.

An accomplished mathematician, i.e. a most wretched orator.
[Closing remark in an address, referring to himself.]

An announcement of [Christopher] Zeeman’s lecture at Northwestern University in the spring of 1977 contains a quote describing catastrophe theory as the most important development in mathematics since the invention of calculus 300 years ago.

An inventive age
Has wrought, if not with speed of magic, yet
To most strange issues. I have lived to mark
A new and unforeseen creation rise
From out the labours of a peaceful Land:
Wielding her potent enginery to frame
And to produce, with appetite as keen
As that of war, which rests not night or day.

An involuntary return to the point of departure is, without doubt, the most disturbing of all journeys.

Analogy is a wonderful, useful and most important form of thinking, and biology is saturated with it. Nothing is worse than a horrible mass of undigested facts, and facts are indigestible unless there is some rhyme or reason to them. The physicist, with his facts, seeks reason; the biologist seeks something very much like rhyme, and rhyme is a kind of analogy.... This analogizing, this fine sweeping ability to see likenesses in the midst of differences is the great glory of biology, but biologists don't know it.... They have always been so fascinated and overawed by the superior prestige of exact physical science that they feel they have to imitate it.... In its central content, biology is not accurate thinking, but accurate observation and imaginative thinking, with great sweeping generalizations.

Analysis and natural philosophy owe their most important discoveries to this fruitful means, which is called induction. Newton was indebted to it for his theorem of the binomial and the principle of universal gravity.

Anaximenes ... said that infinite air was the principle, from which the things that are becoming, and that are, and that shall be, and gods and things divine, all come into being, and the rest from its products. The form of air is of this kind: whenever it is most equable it is invisible to sight, but is revealed by the cold and the hot and the damp and by movement. It is always in motion; for things that change do not change unless there be movement. Through becoming denser or finer it has different appearances; for when it is dissolved into what is finer it becomes fire, while winds, again, are air that is becoming condensed, and cloud is produced from air by felting. When it is condensed still more, water is produced; with a further degree of condensation earth is produced, and when condensed as far as possible, stones. The result is that the most influential components of the generation are opposites, hot and cold.

And do you know what “the world” is to me? Shall I,show it to you in my mirror? This world: a monster of energy, without beginning, without end; a firm, iron magnitude of force that does not grow bigger or smaller, that does not expend itself but only transforms itself; as a whole, of unalterable size, a household without expenses or losses, but likewise without increase or income; enclosed by “nothingness”' as by a boundary; not by something blurry or wasted, not something endlessly extended, but set in a definite space as a definite force, and not a space that might be “empty” here or there, but rather as force throughout, as a play of forces and waves of forces, at the same time one and many, increasing here and at the same time decreasing there; a sea of forces flowing and rushing together, eternally changing, eternally flooding back, with tremendous years of recurrence, with an ebb and a flood of its forms; out of the simplest forms striving toward the most complex, out of the stillest, most rigid, coldest forms toward the hottest, most turbulent, most self-contradictory, and then again returning home to the simple out of this abundance, out of the play of contradictions back to the joy of concord, still affirming itself in this uniformity of its courses and its years, blessing itself as that which must return eternally, as a becoming that knows no satiety, no disgust, no weariness: this, my Dionysian world of the eternally self-creating, the eternally self-destroying, this mystery world of the twofold voluptuous delight, my “beyond good and evil,” without goal, unless the joy of the circle itself is a goal; without will, unless a ring feels good will toward itself-do you want a name for this world? A solution for all its riddles? A light for you, too, you best-concealed, strongest, most intrepid, most midnightly men?—This world is the will to power—and nothing besides! And you yourselves are also this will to power—and nothing besides!

And for rejecting such a Medium, we have the Authority of those the oldest and most celebrated Philosophers of Greece and Phoenicia, who made a Vacuum, and Atoms, and the Gravity of Atoms, the first Principles of their Philosophy; tacitly attributing Gravity to some other Cause than dense Matter. Later Philosophers banish the Consideration of such a Cause out of natural Philosophy, feigning Hypotheses for explaining all things mechanically, and referring other Causes to Metaphysicks: Whereas the main Business of natural Philosophy is to argue from Phaenomena without feigning Hypotheses, and to deduce Causes from Effects, till we come to the very first Cause, which certainly is not mechanical; and not only to unfold the Mechanism of the World, but chiefly to resolve these and such like Questions. What is there in places almost empty of Matter, and whence is it that the Sun and Planets gravitate towards one another, without dense Matter between them? Whence is it that Nature doth nothing in vain; and whence arises all that Order and Beauty which we see in the World? ... does it not appear from phaenomena that there is a Being incorporeal, living, intelligent, omnipresent, who in infinite space, as it were in his Sensory, sees the things themselves intimately, and thoroughly perceives them, and comprehends them wholly by their immediate presence to himself.

And from this such small difference of eight minutes [of arc] it is clear why Ptolemy, since he was working with bisection [of the linear eccentricity], accepted a fixed equant point… . For Ptolemy set out that he actually did not get below ten minutes [of arc], that is a sixth of a degree, in making observations. To us, on whom Divine benevolence has bestowed the most diligent of observers, Tycho Brahe, from whose observations this eight-minute error of Ptolemy’s in regard to Mars is deduced, it is fitting that we accept with grateful minds this gift from God, and both acknowledge and build upon it. So let us work upon it so as to at last track down the real form of celestial motions (these arguments giving support to our belief that the assumptions are incorrect). This is the path I shall, in my own way, strike out in what follows. For if I thought the eight minutes in [ecliptic] longitude were unimportant, I could make a sufficient correction (by bisecting the [linear] eccentricity) to the hypothesis found in Chapter 16. Now, because they could not be disregarded, these eight minutes alone will lead us along a path to the reform of the whole of Astronomy, and they are the matter for a great part of this work.

And so the great truth, now a paradox, may become a commonplace, that man is greater than his surroundings, and that the production of a breed of men and women, even in our great cities, less prone to disease, and pain, more noble in aspect, more rational in habits, more exultant in the pure joy of living, is not only scientifically possible, but that even the partial fulfillment of this dream, if dream it be, is the most worthy object towards which the lover of his kind can devote the best energies of his life.

And what a science Natural History will be, when we are in our graves, when all the laws of change are thought one of the most important parts of Natural History.

And, notwithstanding a few exceptions, we do undoubtedly find that the most truly eminent men have had not only their affections, but also their intellect, greatly influenced by women. I will go even farther; and I will venture to say that those who have not undergone that influence betray a something incomplete and mutilated. We detect, even in their genius, a certain frigidity of tone; and we look in vain for that burning fire, that gushing and spontaneous nature with which our ideas of genius are indissolubly associated. Therefore, it is, that those who are most anxious that the boundaries of knowledge should be enlarged, ought to be most eager that the influence of women should be increased, in order that every resource of the human mind may be at once and quickly brought into play.

Another diversity of Methods is according to the subject or matter which is handled; for there is a great difference in delivery of the Mathematics, which are the most abstracted of knowledges, and Policy, which is the most immersed ... , yet we see how that opinion, besides the weakness of it, hath been of ill desert towards learning, as that which taketh the way to reduce learning to certain empty and barren generalities; being but the very husks and shells of sciences, all the kernel being forced out and expulsed with the torture and press of the method.

Anthropology has been compared to a great region, marked out indeed as within the sphere of influence of science, but unsettled and for the most part unsubdued. Like all such hinterland sciences, it is a happy hunting-ground for adventurers.

Anthropology has reached that point of development where the careful investigation of facts shakes our firm belief in the far-reaching theories that have been built up. The complexity of each phenomenon dawns on our minds, and makes us desirous of proceeding more cautiously. Heretofore we have seen the features common to all human thought. Now we begin to see their differences. We recognize that these are no less important than their similarities, and the value of detailed studies becomes apparent. Our aim has not changed, but our method must change. We are still searching for the laws that govern the growth of human culture, of human thought; but we recognize the fact that before we seek for what is common to all culture, we must analyze each culture by careful and exact methods, as the geologist analyzes the succession and order of deposits, as the biologist examines the forms of living matter. We see that the growth of human culture manifests itself in the growth of each special culture. Thus we have come to understand that before we can build up the theory of the growth of all human culture, we must know the growth of cultures that we find here and there among the most primitive tribes of the Arctic, of the deserts of Australia, and of the impenetrable forests of South America; and the progress of the civilization of antiquity and of our own times. We must, so far as we can, reconstruct the actual history of mankind, before we can hope to discover the laws underlying that history.

Anthropology is the most humanistic of the sciences and the most scientific of the humanities.

Anton Chekhov wrote that ‘one must not put a loaded rifle on stage if no one is thinking of firing it.’ Good drama requires spare and purposive action, sensible linking of potential causes with realized effects. Life is much messier; nothing happens most of the time. Millions of Americans (many hotheaded) own rifles (many loaded), but the great majority, thank God, do not go off most of the time. We spend most of real life waiting for Godot, not charging once more unto the breach.

Any chemist reading this book can see, in some detail, how I have spent most of my mature life. They can become familiar with the quality of my mind and imagination. They can make judgements about my research abilities. They can tell how well I have documented my claims of experimental results. Any scientist can redo my experiments to see if they still work—and this has happened! I know of no other field in which contributions to world culture are so clearly on exhibit, so cumulative, and so subject to verification.

Any frontal attack on ignorance is bound to fail because the masses are always ready to defend their most precious possession: their ignorance.

Any opinion as to the form in which the energy of gravitation exists in space is of great importance, and whoever can make his opinion probable will have, made an enormous stride in physical speculation. The apparent universality of gravitation, and the equality of its effects on matter of all kinds are most remarkable facts, hitherto without exception; but they are purely experimental facts, liable to be corrected by a single observed exception. We cannot conceive of matter with negative inertia or mass; but we see no way of accounting for the proportionality of gravitation to mass by any legitimate method of demonstration. If we can see the tails of comets fly off in the direction opposed to the sun with an accelerated velocity, and if we believe these tails to be matter and not optical illusions or mere tracks of vibrating disturbance, then we must admit a force in that direction, and we may establish that it is caused by the sun if it always depends upon his position and distance.