…resort to science has rendered modern war so destructive of life and property that it presents a new problem to mankind, such, that unless our civilization shall find some means of making an end to war, war will make an end to our civilization.

…so slow is moral progress. True, we have the bicycle, the motor-car, the dirigible airship and other marvellous means of breaking our bones; but our morality is not one rung the higher for it all. One would even say that, the farther we proceed in our conquest of matter, the more our morality recedes. The most advanced of our inventions consists in bringing men down with grapeshot and explosives with the swiftness of the reaper mowing the corn.

“Conservation” (the conservation law) means this … that there is a number, which you can calculate, at one moment—and as nature undergoes its multitude of changes, this number doesn't change. That is, if you calculate again, this quantity, it'll be the same as it was before. An example is the conservation of energy: there's a quantity that you can calculate according to a certain rule, and it comes out the same answer after, no matter what happens, happens.

“Faith” as an imperative is a veto against science—in praxi, it means lies at any price.

“Normal science” means research firmly based upon one or more past scientific achievements, achievements that some particular scientific community acknowledges for a time as supplying the foundation for its further practice.

“Science for its own sake” usually means nothing more than science for the sake of the people who happen to be pursuing it.

“When I use a word,” Humpty Dumpty said, in rather a scornful tone, “it means just what I choose it to mean—neither more nor less.”
“The question is,” said Alice, “whether you can make words mean so many different things.”
“The question is,” said Humpty Dumpty, “which is to be master—that's all.”

“Wu Li” was more than poetic. It was the best definition of physics that the conference would produce. It caught that certain something, that living quality that we were seeking to express in a book, that thing without which physics becomes sterile. “Wu” can mean either “matter” or “energy.” “Li” is a richly poetic word. It means “universal order” or “universal law.” It also means “organic patterns.” The grain in a panel of wood is Li. The organic pattern on the surface of a leaf is also Li, and so is the texture of a rose petal. In short, Wu Li, the Chinese word for physics, means “patterns of organic energy” (“matter/ energy” [Wu] + “universal order/organic patterns” [Li]). This is remarkable since it reflects a world view which the founders of western science (Galileo and Newton) simply did not comprehend, but toward which virtually every physical theory of import in the twentieth century is pointing!

[1155] Mechanics are the Paradise of mathematical science, because here we come to the fruits of mathematics.

[Culture] denotes an historically transmitted pattern of meanings embodied in symbols, a system of inherited conceptions expressed in symbolic forms, by means of which men communicate, perpetuate, and develop their knowledge about and attitudes toward life.

[Decimal currency is desirable because] by that means all calculations of interest, exchange, insurance, and the like are rendered much more simple and accurate, and, of course, more within the power of the great mass of people. Whenever such things require much labor, time, and reflection, the greater number who do not know, are made the dupes of the lesser number who do.

[Kepler] had to realize clearly that logical-mathematical theoretizing, no matter how lucid, could not guarantee truth by itself; that the most beautiful logical theory means nothing in natural science without comparison with the exactest experience. Without this philosophic attitude, his work would not have been possible.

[On the first moon landing:] It means nothing to me. I have no opinion about it, and I don’t care.

[Philosopher Lao-tse] is not dogmatic, and he does not go in for big, universal ideas. For instance, I like what he says about failure and success, “Failure is the foundation of success and the means by which it is achieved. Success is the lurking place of failure; but who can tell when the turning point will come?”

[Public cynicism towards professional expertise is] entirely wrong, and it’s the road back to the cave. The way we got out of the caves and into modern civilisation is through the process of understanding and thinking. Those things were not done by gut instinct. Being an expert does not mean that you are someone with a vested interest in something; it means you spend your life studying something. You’re not necessarily right–but you’re more likely to be right than someone who’s not spent their life studying it.

[T]here are depths of thousands of miles which are hidden from our inquiry. The only tidings we have from those unfathomable regions are by means of volcanoes, those burning mountains that seem to discharge their materials from the lowest abysses of the earth.

[The attitude of the Renaissance towards the antique world was that] Archaeology to them was not a mere science for the antiquarian; it was a means by which they could touch the dry dust of antiquity into the very breath and beauty of life, and fill with the new wine of romanticism forms that else had been old and out-worn.

[Defining Organism] That in which every part is at once means and end.

[When asked “Dr. Einstein, why is it that when the mind of man has stretched so far as to discover the structure of the atom we have been unable to devise the political means to keep the atom from destroying us?”] That is simple, my friend. It is because politics is more difficult than physics.

A stands for atom; it is so small No one has ever seen it at all.
B stands for bomb; the bombs are much bigger,
So, brother, do not be too fast on the trigger.
H has become a most ominous letter.
It means something bigger if not something better.

Branches or types are characterized by the plan of their structure,
Classes, by the manner in which that plan is executed, as far as ways and means are concerned,
Orders, by the degrees of complication of that structure,
Families, by their form, as far as determined by structure,
Genera, by the details of the execution in special parts, and
Species, by the relations of individuals to one another and to the world in which they live, as well as by the proportions of their parts, their ornamentation, etc.

Conclusions
I. A curve has been found representing the frequency distribution of standard deviations of samples drawn from a normal population.
II. A curve has been found representing the frequency distribution of values of the means of such samples, when these values are measured from the mean of the population in terms of the standard deviation of the sample…
IV. Tables are given by which it can be judged whether a series of experiments, however short, have given a result which conforms to any required standard of accuracy or whether it is necessary to continue the investigation.

Les grands ponts étant … des monuments qui peuvent servir à faire connoître la magnificence et le génie d’une nation, on ne sauroit trop s’occuper des moyens d’en perfectionner l’architecture, qui peut d’ailleurs être susceptible de variété, en conservant toujours, dans les formes et la décoration, le caractere de solidité qui lui est propre.
Great bridges being monuments which serve to make known the grandeur and genius of a nation, we cannot pay too much attention to means for perfecting their architecture; this may be varied in treatment, but there must ever be conserved, in form and in decoration, the indispensable character of solidity.

Mathematical truth has validity independent of place, personality, or human authority. Mathematical relations are not established, nor can they be abrogated, by edict. The multiplication table is international and permanent, not a matter of convention nor of relying upon authority of state or church. The value of π is not amenable to human caprice. The finding of a mathematical theorem may have been a highly romantic episode in the personal life of the discoverer, but it cannot be expected of itself to reveal the race, sex, or temperament of this discoverer. With modern means of widespread communication even mathematical notation tends to be international despite all nationalistic tendencies in the use of words or of type.

Parkinson's Third Law: Expansion means complexity, and complexity decay.

Responding to the Bishop of Oxford, Samuel Wilberforce's question whether he traced his descent from an ape on his mother's or his father's side:
If then, said I, the question is put to me would I rather have a miserable ape for a grandfather or a man highly endowed by nature and possessing great means and influence and yet who employs those faculties for the mere purpose of introducing ridicule into a grave scientific discussion—I unhesitatingly affirm my preference for the ape.

Wenn sich für ein neues Fossil kein, auf eigenthümliche Eigenschaften desselben hinweisender, Name auffinden lassen Will; als in welchem Falle ich mich bei dem gegenwärtigen zu befinden gestehe; so halte ich es für besser, eine solche Benennung auszuwählen, die an sich gar nichts sagt, und folglich auch zu keinen unrichtigen Begriffen Anlass geben kann. Diesem zufolge will ich den Namen für die gegenwärtige metallische Substanz, gleichergestalt wie bei dem Uranium geschehen, aus der Mythologie, und zwar von den Ursöhnen der Erde, den Titanen, entlehnen, und benenne also dieses neue Metallgeschlecht: Titanium.
Wherefore no name can be found for a new fossil [element] which indicates its peculiar and characteristic properties (in which position I find myself at present), I think it is best to choose such a denomination as means nothing of itself and thus can give no rise to any erroneous ideas. In consequence of this, as I did in the case of Uranium, I shall borrow the name for this metallic substance from mythology, and in particular from the Titans, the first sons of the earth. I therefore call this metallic genus TITANIUM.

~~[Dubious]~~ I demonstrate by means of philosophy that the earth is round, and is inhabited on all sides; that it is insignificantly small, and is borne through the stars.

1. Universal CHEMISTRY is the Art of resolving mixt, compound, or aggregate Bodies into their Principles; and of composing such Bodies from those Principles. 2. It has for its Subject all the mix’d, compound, and aggregate Bodies that are and resolvable and combinable and Resolution and Combination, or Destruction and Generation, for its Object. 3. Its Means in general, are either remote or immediate; that is, either Instruments or the Operations themselves. 4. Its End is either philosophical and theoretical; or medicinal, mechanical, œconomical, and practical. 5. Its efficient Cause is the Chemist.

1839—The fermentation satire
THE MYSTERY OF ALCOHOLIC FERMENTATION RESOLVED
(Preliminary Report by Letter) Schwindler
I am about to develop a new theory of wine fermentation … Depending on the weight, these seeds carry fermentation to completion somewhat less than as in the beginning, which is understandable … I shall develop a new theory of wine fermentation [showing] what simple means Nature employs in creating the most amazing phenomena. I owe it to the use of an excellent microscope designed by Pistorius.
When brewer’s yeast is mixed with water the microscope reveals that the yeast dissolves into endless small balls, which are scarcely 1/800th of a line in diameter … If these small balls are placed in sugar water, it can be seen that they consist of the eggs of animals. As they expand, they burst, and from them develop small creatures that multiply with unbelievable rapidity in a most unheard of way. The form of these animals differs from all of the 600 types described up until now. They possess the shape of a Beinsdorff still (without the cooling apparatus). The head of the tube is a sort of proboscis, the inside of which is filled with fine bristles 1/2000th of a line long. Teeth and eyes are not discernible; however, a stomach, intestinal canal, anus (a rose red dot), and organs for secretion of urine are plainly discernible. From the moment they are released from the egg one can see these animals swallow the sugar from the solution and pass it to the stomach. It is digested immediately, a process recognized easily by the resultant evacuation of excrements. In a word, these infusors eat sugar, evacuate ethyl alcohol from the intestinal canal, and carbon dioxide from the urinary organs. The bladder, in the filled state, has the form of a champagne bottle; when empty, it is a small button … As soon as the animals find no more sugar present, they eat each other up, which occurs through a peculiar manipulation; everything is digested down to the eggs which pass unchanged through the intestinal canal. Finally, one again fermentable yeast, namely the seed of the animals, which remain over.

A general course in mathematics should be required of all officers for its practical value, but no less for its educational value in training the mind to logical forms of thought, in developing the sense of absolute truthfulness, together with a confidence in the accomplishment of definite results by definite means.

A Law of Nature, (Lex Naturalis) is a Precept, or generall Rule, found out by Reason, by which a man is forbidden to do, that, which is destructive of his life, or taketh away the means of preserving the same; and to omit, that, by which he thinketh it may be best preserved.

A bird maintains itself in the air by imperceptible balancing, when near to the mountains or lofty ocean crags; it does this by means of the curves of the winds which as they strike against these projections, being forced to preserve their first impetus bend their straight course towards the sky with divers revolutions, at the beginning of which the birds come to a stop with their wings open, receiving underneath themselves the continual buffetings of the reflex courses of the winds.

A closer look at the course followed by developing theory reveals for a start that it is by no means as continuous as one might expect, but full of breaks and at least apparently not along the shortest logical path. Certain methods often afforded the most handsome results only the other day, and many might well have thought that the development of science to infinity would consist in no more than their constant application. Instead, on the contrary, they suddenly reveal themselves as exhausted and the attempt is made to find other quite disparate methods. In that event there may develop a struggle between the followers of the old methods and those of the newer ones. The former's point of view will be termed by their opponents as out-dated and outworn, while its holders in turn belittle the innovators as corrupters of true classical science.

A conflict arises when a religious community insists on the absolute truthfulness of all statements recorded in the Bible. This means an intervention on the part of religion into the sphere of science; this is where the struggle of the Church against the doctrines of Galileo and Darwin belongs. On the other hand, representatives of science have often made an attempt to arrive at fundamental judgments with respect to values and ends on the basis of scientific method, and in this way have set themselves in opposition to religion. These conflicts have all sprung from fatal errors.

A first step in the study of civilization is to dissect it into details, and to classify these in their proper groups. Thus, in examining weapons, they are to be classed under spear, club, sling, bow and arrow, and so forth; among textile arts are to be ranged matting, netting, and several grades of making and weaving threads; myths are divided under such headings as myths of sunrise and sunset, eclipse-myths, earthquake-myths, local myths which account for the names of places by some fanciful tale, eponymic myths which account for the parentage of a tribe by turning its name into the name of an imaginary ancestor; under rites and ceremonies occur such practices as the various kinds of sacrifice to the ghosts of the dead and to other spiritual beings, the turning to the east in worship, the purification of ceremonial or moral uncleanness by means of water or fire. Such are a few miscellaneous examples from a list of hundreds … To the ethnographer, the bow and arrow is the species, the habit of flattening children’s skulls is a species, the practice of reckoning numbers by tens is a species. The geographical distribution of these things, and their transmission from region to region, have to be studied as the naturalist studies the geography of his botanical and zoological species.

A great discovery solves a great problem, but there is a grain of discovery in the solution of any problem. Your problem may be modest, but if it challenges your curiosity and brings into play your inventive faculties, and if you solve it by your own means, you may experience the tension and enjoy the triumph of discovery.

A great surgeon performs operations for stone by a single method; later he makes a statistical summary of deaths and recoveries, and he concludes from these statistics that the mortality law for this operation is two out of five. Well, I say that this ratio means literally nothing scientifically and gives us no certainty in performing the next operation; for we do not know whether the next case will be among the recoveries or the deaths. What really should be done, instead of gathering facts empirically, is to study them more accurately, each in its special determinism. We must study cases of death with great care and try to discover in them the cause of mortal accidents so as to master the cause and avoid the accidents.

A man has a very insecure tenure of a property which another can carry away with his eyes. A few months reduced me to the cruel necessity either of destroying my machine, or of giving it to the public. To destroy it, I could not think of; to give up that for which I had laboured so long, was cruel. I had no patent, nor the means of purchasing one. In preference to destroying, I gave it to the public.
[On his inability to keep for himself a profitable income from his invention of the Spinning Mule.]

A professor of experimental science must sometimes grab at any, even senseless, means to impress scientific laws [on students]. Sometimes, one can only capture what is most important about beautiful drastic experiments with a joke. Nothing conveys it better!

A rock or stone is not a subject that, of itself, may interest a philosopher to study; but, when he comes to see the necessity of those hard bodies, in the constitution of this earth, or for the permanency of the land on which we dwell, and when he finds that there are means wisely provided for the renovation of this necessary decaying part, as well as that of every other, he then, with pleasure, contemplates this manifestation of design, and thus connects the mineral system of this earth with that by which the heavenly bodies are made to move perpetually in their orbits.

A star is drawing on some vast reservoir of energy by means unknown to us. This reservoir can scarcely be other than the subatomic energy which, it is known exists abundantly in all matter; we sometimes dream that man will one day learn how to release it and use it for his service. The store is well nigh inexhaustible, if only it could be tapped. There is sufficient in the Sun to maintain its output of heat for 15 billion years.

A State without the means of some change is without the means of its conservation.

A teacher of mathematics has a great opportunity. If he fills his allotted time with drilling his students in routine operations he kills their interest, hampers their intellectual development, and misuses his opportunity. But if he challenges the curiosity of his students by setting them problems proportionate to their knowledge, and helps them to solve their problems with stimulating questions, he may give them a taste for, and some means of, independent thinking.

A tidy laboratory means a lazy chemist.

A time will come when science will transform [our bodies] by means which we cannot conjecture... And then, the earth being small, mankind will migrate into space, and will cross the airless Saharas which separate planet from planet, and sun from sun. The earth will become a Holy Land which will be visited by pilgrims from all quarters of the universe.

About ten months ago [1609] a report reached my ears that a certain Fleming [Hans Lippershey] had constructed a spyglass, by means of which visible objects, though very distant from the eye of the observer, were distinctly seen as if nearby... Of this truly remarkable effect several experiences were related, to which some persons gave credence while others denied them. A few days later the report was confirmed to me in a letter from a noble Frenchman at Paris, Jacques Badovere, which caused me to apply myself wholeheartedly to enquire into the means by which I might arrive at the invention of a similar instrument. This I did shortly afterwards, my basis being the theory of refraction. First I prepared a tube of lead, at the ends of which I fitted two glass lenses, both plane on one side while on the other side one was spherically convex and the other concave.

About the year 1772, being then an apprentice to a wheel-wright, or wagon maker, I laboured to discover some means of propelling land carriages without animal power. … one of my brothers [told me of] blacksmith’s boys, who, for amusement, had stopped up the touch hole of a gun barrel, then put in about a gill of water, and rammed down a tight wad; after which they put the breech in the smith’s fire, when it discharged itself with as loud a crack as if it had been loaded with powder. It immediately occurred to me, that here was the power to propel any wagon, if I could only apply it.

Absolute, true, and mathematical time, in and of itself and of its own nature, without reference to anything external, flows uniformly and by another name is called duration. Relative, apparent, and common time is any sensible and external measure (precise or imprecise) of duration by means of motion; such as a measure—for example, an hour, a day, a month, a year—is commonly used instead of true time.

Across the road from my cabin was a huge clear-cut—hundreds of acres of massive spruce stumps interspersed with tiny Douglas firs—products of what they call “Reforestation,” which I guess makes the spindly firs en masse a “Reforest,” which makes an individual spindly fir a “Refir,” which means you could say that Weyerhauser, who owns the joint, has Refir Madness, since they think that sawing down 200-foot-tall spruces and replacing them with puling 2-foot Refirs is no different from farming beans or corn or alfalfa. They even call the towering spires they wipe from the Earth’s face forever a “crop”--as if they’d planted the virgin forest! But I'm just a fisherman and may be missing some deeper significance in their nomenclature and stranger treatment of primordial trees.

Agnosticism is of the essence of science, whether ancient or modern. It simply means that a man shall not say he knows or believes that for which he has no grounds for professing to believe.

All progress is based upon a universal innate desire of every organism to live beyond its means.

All that can be said upon the number and nature of elements is, in my opinion, confined to discussions entirely of a metaphysical nature. The subject only furnishes us with indefinite problems, which may be solved in a thousand different ways, not one of which, in all probability, is consistent with nature. I shall therefore only add upon this subject, that if, by the term elements, we mean to express those simple and indivisible atoms of which matter is composed, it is extremely probable we know nothing at all about them; but, if we apply the term elements, or principles of bodies, to express our idea of the last point which analysis is capable of reaching, we must admit, as elements, all the substances into which we are capable, by any means, to reduce bodies by decomposition.

All the truths of mathematics are linked to each other, and all means of discovering them are equally admissible.

All these delusions of Divination have their root and foundation from Astrology. For whether the lineaments of the body, countenance, or hand be inspected, whether dream or vision be seen, whether marking of entrails or mad inspiration be consulted, there must be a Celestial Figure first erected, by the means of whole indications, together with the conjectures of Signs and Similitudes, they endeavour to find out the truth of what is desired.

All true science must aim at objective truth, and that means that the human observer must never allow himself to get emotionally mixed up with his subject-matter. His concern is to understand the universe, not to improve it. Detachment is obligatory.

America has never been united by blood or birth or soil. We are bound by ideals that move us beyond our backgrounds, lift us above our interests and teach us what it means to be citizens. Every child must be taught these principles. Every citizen must uphold them. And every immigrant, by embracing these ideals, makes our country more, not less, American.

Among innumerable footsteps of divine providence to be found in the works of nature, there is a very remarkable one to be observed in the exact balance that is maintained, between the numbers of men and women; for by this means is provided, that the species never may fail, nor perish, since every male may have its female, and of proportionable age. This equality of males and females is not the effect of chance but divine providence, working for a good end, which I thus demonstrate.

An equation means nothing to me unless it expresses a thought of God.

An infinity of these tiny animals defoliate our plants, our trees, our fruits... they attack our houses, our fabrics, our furniture, our clothing, our furs ... He who in studying all the different species of insects that are injurious to us, would seek means of preventing them from harming us, would seek to cause them to perish, proposes for his goal important tasks indeed.

An inventor is an opportunist, one who takes occasion by the hand; who, having seen where some want exists, successfully applies the right means to attain the desired end. The means may be largely, or even wholly, something already known, or there may be a certain originality or discovery in the means employed. But in every case the inventor uses the work of others. If I may use a metaphor, I should liken him to the man who essays the conquest of some virgin alp. At the outset he uses the beaten track, and, as he progresses in the ascent, he uses the steps made by those who have preceded him, whenever they lead in the right direction; and it is only after the last footprints have died out that he takes ice-axe in hand and cuts the remaining steps, few or many, that lift him to the crowning height which is his goal.

An inventor is one who can see the applicability of means to supply demand five years before it is obvious to those skilled in the art.

An organized product of nature is that in which all the parts are mutually ends and means.

An unelectrified atom is so elusive that unless more than a million million are present we have no means sufficiently sensitive to detect them, or, to put it another way, unless we had a better test for a man than for an unelectrified molecule, we should be unable to find out that the earth was inhabited. … A billion unelectrified atoms may escape our observation, whereas a dozen or so electrified ones are detected without difficulty.

Analysis and natural philosophy owe their most important discoveries to this fruitful means, which is called induction. Newton was indebted to it for his theorem of the binomial and the principle of universal gravity.

Any conception which is definitely and completely determined by means of a finite number of specifications, say by assigning a finite number of elements, is a mathematical conception. Mathematics has for its function to develop the consequences involved in the definition of a group of mathematical conceptions. Interdependence and mutual logical consistency among the members of the group are postulated, otherwise the group would either have to be treated as several distinct groups, or would lie beyond the sphere of mathematics.

Archimedes [indicates] that there can be no true levelling by means of water, because he holds that water has not a level surface, but is of a spherical form, having its centre at the centre of the earth.

Archimedes possessed so high a spirit, so profound a soul, and such treasures of highly scientific knowledge, that though these inventions [used to defend Syracuse against the Romans] had now obtained him the renown of more than human sagacity, he yet would not deign to leave behind him any commentary or writing on such subjects; but, repudiating as sordid and ignoble the whole trade of engineering, and every sort of art that lends itself to mere use and profit, he placed his whole affection and ambition in those purer speculations where there can be no reference to the vulgar needs of life; studies, the superiority of which to all others is unquestioned, and in which the only doubt can be whether the beauty and grandeur of the subjects examined, or the precision and cogency of the methods and means of proof, most deserve our admiration.

Art and Religion are, then, two roads by which men escape from circumstance to ecstasy. Between aesthetic and religious rapture there is a family alliance. Art and Religion are means to similar states of mind.

Art and science coincide insofar as both aim to improve the lives of men and women. The latter normally concerns itself with profit, the former with pleasure. In the coming age, art will fashion our entertainment out of new means of productivity in ways that will simultaneously enhance our profit and maximize our pleasure.

As every circumstance relating to so capital a discovery as this (the greatest, perhaps, that has been made in the whole compass of philosophy, since the time of Sir Isaac Newton) cannot but give pleasure to all my readers, I shall endeavour to gratify them with the communication of a few particulars which I have from the best authority. The Doctor [Benjamin Franklin], after having published his method of verifying his hypothesis concerning the sameness of electricity with the matter lightning, was waiting for the erection of a spire in Philadelphia to carry his views into execution; not imagining that a pointed rod, of a moderate height, could answer the purpose; when it occurred to him, that, by means of a common kite, he could have a readier and better access to the regions of thunder than by any spire whatever. Preparing, therefore, a large silk handkerchief, and two cross sticks, of a proper length, on which to extend it, he took the opportunity of the first approaching thunder storm to take a walk into a field, in which there was a shed convenient for his purpose. But dreading the ridicule which too commonly attends unsuccessful attempts in science, he communicated his intended experiment to no body but his son, who assisted him in raising the kite.
The kite being raised, a considerable time elapsed before there was any appearance of its being electrified. One very promising cloud passed over it without any effect; when, at length, just as he was beginning to despair of his contrivance, he observed some loose threads of the hempen string to stand erect, and to avoid one another, just as if they had been suspended on a common conductor. Struck with this promising appearance, he inmmediately presented his knuckle to the key, and (let the reader judge of the exquisite pleasure he must have felt at that moment) the discovery was complete. He perceived a very evident electric spark. Others succeeded, even before the string was wet, so as to put the matter past all dispute, and when the rain had wetted the string, he collected electric fire very copiously. This happened in June 1752, a month after the electricians in France had verified the same theory, but before he had heard of any thing that they had done.

As for “Don’t be evil,” we have tried to define precisely what it means to be a force for good—always do the right, ethical thing. Ultimately, “Don’t be evil” seems the easiest way to summarize it.

As ideas are preserved and communicated by means of words, it necessarily follows that we cannot improve the language of any science, without at the same time improving the science itself; neither can we, on the other hand, improve a science without improving the language or nomenclature which belongs to it.

As science is more and more subject to grave misuse as well as to use for human benefit it has also become the scientist's responsibility to become aware of the social relations and applications of his subject, and to exert his influence in such a direction as will result in the best applications of the findings in his own and related fields. Thus he must help in educating the public, in the broad sense, and this means first educating himself, not only in science but in regard to the great issues confronting mankind today.

As there is not in human observation proper means for measuring the waste of land upon the globe, it is hence inferred, that we cannot estimate the duration of what we see at present, nor calculate the period at which it had begun; so that, with respect to human observation, this world has neither a beginning nor an end.

As was predicted at the beginning of the Human Genome Project, getting the sequence will be the easy part as only technical issues are involved. The hard part will be finding out what it means, because this poses intellectual problems of how to understand the participation of the genes in the functions of living cells.

At last gleams of light have come, and I am almost convinced (quite contrary to opinion I started with) that species are not (it is like confessing a murder) immutable. Heaven forfend me from Lamarck nonsense of a “tendency to progression”, “adaptations from the slow willing of animals”, &c! But the conclusions I am led to are not widely different from his; though the means of change are wholly so. I think I have found out (here’s presumption!) the simple way by which species become exquisitely adapted to various ends.

At the present time there exist problems beyond our ability to solve, not because of theoretical difficulties, but because of insufficient means of mechanical computation.

Basic research at universities comes in two varieties: research that requires big bucks and research that requires small bucks. Big bucks research is much like government research and in fact usually is government research but done for the government under contract. Like other government research, big bucks academic research is done to understand the nature and structure of the universe or to understand life, which really means that it is either for blowing up the world or extending life, whichever comes first. Again, that's the government's motivation. The universities' motivation for conducting big bucks research is to bring money in to support professors and graduate students and to wax the floors of ivy-covered buildings. While we think they are busy teaching and learning, these folks are mainly doing big bucks basic research for a living, all the while priding themselves on their terrific summer vacations and lack of a dress code.
Smalls bucks research is the sort of thing that requires paper and pencil, and maybe a blackboard, and is aimed primarily at increasing knowledge in areas of study that don't usually attract big bucks - that is, areas that don't extend life or end it, or both. History, political science, and romance languages are typically small bucks areas of basic research. The real purpose of small bucks research to the universities is to provide a means of deciding, by the quality of their small bucks research, which professors in these areas should get tenure.

Because words pass away as soon as they strike upon the air, and last no longer than their sound, men have by means of letters formed signs of words. Thus the sounds of the voice are made visible to the eye, not of course as sounds, but by means of certain signs.

Before his [Sir Astley Cooper’s] time, operations were too often frightful alternatives or hazardous compromises; and they were not seldom considered rather as the resource of despair than as a means of remedy; he always made them follow, as it were, in the natural course of treatment; he gave them a scientific character; and he moreover, succeeded, in a great degree, in divesting them of their terrors, by performing them unostentatiously, simply, confidently, and cheerfully, and thereby inspiring the patient with hope of relief, where previously resignation under misfortune had too often been all that could be expected from the sufferer.

Behavioral avoidance, not physiological adaptations, is an organism’s primary response to an environmental challenge. This point is elementary, but it is by no means trivial.

Besides electrical engineering theory of the transmission of messages, there is a larger field [cybernetics] which includes not only the study of language but the study of messages as a means of controlling machinery and society, the development of computing machines and other such automata, certain reflections upon psychology and the nervous system, and a tentative new theory of scientific method.

Biologists have long attempted by chemical means to induce in higher organisms predictable and specific changes which thereafter could be transmitted in series as hereditary characters. Among microorganisms the most striking example of inheritable and specific alterations in cell structure and function that can be experimentally induced and are reproducible under well defined and adequately controlled conditions is the transformation of specific types of Pneumococcus.

Biology is the only science in which multiplication means the same thing as division.

Broadly speaking, we are in the middle of a race between human skill as a means and human folly as an end.

But as my conclusions have lately been much misrepresented, and it has been stated that I attribute the modification of species exclusively to natural selection, I may be permitted to remark that in the first edition of this work, and subsequently, I placed in a most conspicuous position—namely, at the close of the Introduction—the following words: “I am convinced that natural selection has been the main but not the exclusive means of modification.” This has been of no avail. Great is the power of steady misrepresentation; but the history of science shows that fortunately this power does not long endure.

But I do not feel obliged to believe that that same God who has endowed us with senses, reason, and intellect has intended to forgo their use and by some other means to give us knowledge which we can attain by them.

But I shall certainly admit a system as empirical or scientific only if it is capable of being tested by experience. These considerations suggest that not the verifiability but the falsifiability of a system is to be taken as a criterion of demarcation. In other words: I shall not require of a scientific system that it shall be capable of being singled out, once and for all, in a positive sense; but I shall require that its logical form shall be such that it can be singled out, by means of empirical tests, in a negative sense: it must be possible for an empirical scientific system to be refuted by experience. (1959)

But medicine has long had all its means to hand, and has discovered both a principle and a method, through which the discoveries made during a long period are many and excellent, while full discovery will be made, if the inquirer be competent, conduct his researches with knowledge of the discoveries already made, and make them his starting-point. But anyone who, casting aside and rejecting all these means, attempts to conduct research in any other way or after another fashion, and asserts that he has found out anything, is and has been victim of deception.

But regular biology, as an "ology," has to be "scientific," and this means in practice that it has to be made dull.... Everything has to be expressed in utterly impersonal terms.

But we shall not satisfy ourselves simply with improving steam and explosive engines or inventing new batteries; we have something much better to work for, a greater task to fulfill. We have to evolve means for obtaining energy from stores which are forever inexhaustible, to perfect methods which do not imply consumption and waste of any material whatever.

By destroying the biological character of phenomena, the use of averages in physiology and medicine usually gives only apparent accuracy to the results. From our point of view, we may distinguish between several kinds of averages: physical averages, chemical averages and physiological and pathological averages. If, for instance, we observe the number of pulsations and the degree of blood pressure by means of the oscillations of a manometer throughout one day, and if we take the average of all our figures to get the true or average blood pressure and to learn the true or average number of pulsations, we shall simply have wrong numbers. In fact, the pulse decreases in number and intensity when we are fasting and increases during digestion or under different influences of movement and rest; all the biological characteristics of the phenomenon disappear in the average. Chemical averages are also often used. If we collect a man's urine during twenty-four hours and mix all this urine to analyze the average, we get an analysis of a urine which simply does not exist; for urine, when fasting, is different from urine during digestion. A startling instance of this kind was invented by a physiologist who took urine from a railroad station urinal where people of all nations passed, and who believed he could thus present an analysis of average European urine! Aside from physical and chemical, there are physiological averages, or what we might call average descriptions of phenomena, which are even more false. Let me assume that a physician collects a great many individual observations of a disease and that he makes an average description of symptoms observed in the individual cases; he will thus have a description that will never be matched in nature. So in physiology, we must never make average descriptions of experiments, because the true relations of phenomena disappear in the average; when dealing with complex and variable experiments, we must study their various circumstances, and then present our most perfect experiment as a type, which, however, still stands for true facts. In the cases just considered, averages must therefore be rejected, because they confuse, while aiming to unify, and distort while aiming to simplify. Averages are applicable only to reducing very slightly varying numerical data about clearly defined and absolutely simple cases.

By means of the Mummy, mankind, it is said,
Attests to the gods its respect for the dead.
We plunder his tomb, be he sinner or saint,
Distill him for physic and grind him for paint,
Exhibit for money his poor, shrunken frame,
And with levity flock to the scene of the shame.
O, tell me, ye gods, for the use of my rhyme:
For respecting the dead what’s the limit of time?

Can any thoughtful person admit for a moment that, in a society so constituted that these overwhelming contrasts of luxury and privation are looked upon as necessities, and are treated by the Legislature as matters with which it has practically nothing do, there is the smallest probability that we can deal successfully with such tremendous social problems as those which involve the marriage tie and the family relation as a means of promoting the physical and moral advancement of the race? What a mockery to still further whiten the sepulchre of society, in which is hidden ‘all manner of corruption,’ with schemes for the moral and physical advancement of the race!

Chemistry is one of those branches of human knowledge which has built itself upon methods and instruments by which truth can presumably be determined. It has survived and grown because all its precepts and principles can be re-tested at any time and anywhere. So long as it remained the mysterious alchemy by which a few devotees, by devious and dubious means, presumed to change baser metals into gold, it did not flourish, but when it dealt with the fact that 56 g. of fine iron, when heated with 32 g. of flowers of sulfur, generated extra heat and gave exactly 88 g. of an entirely new substance, then additional steps could be taken by anyone. Scientific research in chemistry, since the birth of the balance and the thermometer, has been a steady growth of test and observation. It has disclosed a finite number of elementary reagents composing an infinite universe, and it is devoted to their inter-reaction for the benefit of mankind.

Chymistry. … An art whereby sensible bodies contained in vessels … are so changed, by means of certain instruments, and principally fire, that their several powers and virtues are thereby discovered, with a view to philosophy or medicine.

Combining in our survey then, the whole range of deposits from the most recent to the most ancient group, how striking a succession do they present:– so various yet so uniform–so vast yet so connected. In thus tracing back to the most remote periods in the physical history of our continents, one system of operations, as the means by which many complex formations have been successively produced, the mind becomes impressed with the singleness of nature's laws; and in this respect, at least, geology is hardly inferior in simplicity to astronomy.

Concerning the gods, I have no means of knowing either that they exist or that they do not exist, nor what sort of form they may have; there are many reasons why knowledge on this subject is not possible, owing to the lack of evidence and the shortness of human life.

Conservation means development as much as it does protection. I recognize the right and duty of this generation to develop and use the natural resources of our land; but I do not recognize the right to waste them, or to rob, by wasteful use, the generations that come after us.

Conservation means the wise use of the earth and its resources for the lasting good of men.

CREATION OF LIFE.
The Startling Discovery of Prof. Loeb.
Lower Animals Produced by Chemical Means.
Process May Apply to the Human Species.
Immaculate Conception is Explained.
Wonderful Experiments Conducted at Woods Hole.

Curiosity that inborn property of man, daughter of ignorance and mother of knowledge when wonder wakens our minds, has the habit, wherever it sees some extraordinary phenomenon of nature, a comet for example, a sun-dog, or a midday star, of asking straightway what it means.

Darwin was a biological evolutionist, because he was first a uniformitarian geologist. Biology is pre-eminent to-day among the natural sciences, because its younger sister, Geology, gave it the means.

Descriptive geometry has two objects: the first is to establish methods to represent on drawing paper which has only two dimensions,—namely, length and width,—all solids of nature which have three dimensions,—length, width, and depth,—provided, however, that these solids are capable of rigorous definition.
The second object is to furnish means to recognize accordingly an exact description of the forms of solids and to derive thereby all truths which result from their forms and their respective positions.

Disease is largely a removable evil. It continues to afflict humanity, not only because of incomplete knowledge of its causes and lack of individual and public hygiene, but also because it is extensively fostered by harsh economic and industrial conditions and by wretched housing in congested communities. ... The reduction of the death rate is the principal statistical expression and index of human social progress. It means the saving and lengthening of lives of thousands of citizens, the extension of the vigorous working period well into old age, and the prevention of inefficiency, misery, and suffering. These advances can be made by organized social effort. Public health is purchasable. (1911)

Doctors in all ages have made fortunes by killing their patients by means of their cures. The difference in psychiatry is that is the death of the soul.

Does it mean, if you don’t understand something, and the community of physicists don’t understand it, that means God did it? Is that how you want to play this game? Because if it is, here’s a list of the things in the past that the physicists—at the time—didn’t understand … [but now we do understand.] If that’s how you want to invoke your evidence for God, then God is an ever-receding pocket of scientific ignorance, that’s getting smaller and smaller and smaller, as time moves on. So just be ready for that to happen, if that’s how you want to come at the problem. That’s simply the “God of the Gaps” argument that’s been around for ever.

During my span of life science has become a matter of public concern and the l'art pour l'art standpoint of my youth is now obsolete. Science has become an integral and most important part of our civilization, and scientific work means contributing to its development. Science in our technical age has social, economic, and political functions, and however remote one's own work is from technical application it is a link in the chain of actions and decisions which determine the fate of the human race. I realized this aspect of science in its full impact only after Hiroshima.

Education is a mechanism for inducing change and for providing the means of accommodation and adjustment to change. At the same time, as an institution, education is given the responsibility for insuring the preservation and transfer and therefore, the continuity of society’s knowledge, skills, and values.

Engineering is a living branch of human activity and its frontiers are by no means exhausted.

Engineering is the art of directing the great sources of power in nature for the use and the convenience of people. In its modern form engineering involves people, money, materials, machines, and energy. It is differentiated from science because it is primarily concerned with how to direct to useful and economical ends the natural phenomena which scientists discover and formulate into acceptable theories. Engineering therefore requires above all the creative imagination to innovate useful applications of natural phenomena. It seeks newer, cheaper, better means of using natural sources of energy and materials.

Engineering is the art or science of utilizing, directing or instructing others in the utilization of the principles, forces, properties and substance of nature in the production, manufacture, construction, operation and use of things ... or of means, methods, machines, devices and structures ...

Engineering is the practice of safe and economic application of the scientific laws governing the forces and materials of nature by means of organization, design and construction, for the general benefit of mankind.

Even though the realms of religion and science in themselves are clearly marked off from each other, nevertheless there exist between the two strong reciprocal relationships and dependencies. Though religion may be that which determines the goal, it has, nevertheless, learned from science, in the broadest sense, what means will contribute to the attainment of the goals it has set up. But science can only be created by those who are thoroughly imbued with the aspiration toward truth and understanding. This source of feeling, however, springs from the sphere of religion. To this there also belongs the faith in the possibility that the regulations valid for the world of existence are rational, that is, comprehensible to reason. I cannot conceive of a genuine scientist without that profound faith. The situation may be expressed by an image: science without religion is lame, religion without science is blind.

Every great anthropologic and paleontologic discovery fits into its proper place, enabling us gradually to fill out, one after another, the great branching lines of human ascent and to connect with the branches definite phases of industry and art. This gives us a double means of interpretation, archaeological and anatomical. While many branches and links in the chain remain to be discovered, we are now in a position to predict with great confidence not only what the various branches will be like but where they are most like to be found.

Every rule has its limits, and every concept its ambiguities. Most of all is this true in the science of life, where nothing quite corresponds to our ideas; similar ends are reached by varied means, and no causes are simple.

Every time we get slapped down, we can say, “Thank you Mother Nature,” because it means we’re about to learn something important.

Everything that the greatest minds of all times have accomplished toward the comprehension of forms by means of concepts is gathered into one great science, mathematics.

Extinction has only separated groups: it has by no means made them; for if every form which has ever lived on this earth were suddenly to reappear, though it would be quite impossible to give definitions by which each group could be distinguished from other groups, as all would blend together by steps as fine as those between the finest existing varieties, nevertheless a natural classification, or at least a natural arrangement, would be possible.

Finally, in regard to those who possess the largest shares in the stock of worldly goods, could there, in your opinion, be any police so vigilant and effetive, for the protections of all the rights of person, property and character, as such a sound and comprehensive education and training, as our system of Common Schools could be made to impart; and would not the payment of a sufficient tax to make such education and training universal, be the cheapest means of self-protection and insurance?

First, by what means it is that a Plant, or any Part of it, comes to Grow, a Seed to put forth a Root and Trunk... How the Aliment by which a Plant is fed, is duly prepared in its several Parts ... How not only their Sizes, but also their Shapes are so exceedingly various ... Then to inquire, What should be the reason of their various Motions; that the Root should descend; that its descent should sometimes be perpendicular, sometimes more level: That the Trunk doth ascend, and that the ascent thereof, as to the space of Time wherein it is made, is of different measures... Further, what may be the Causes as of the Seasons of their Growth; so of the Periods of their Lives; some being Annual, others Biennial, others Perennial ... what manner the Seed is prepared, formed and fitted for Propagation.