… There can be no doubt about faith and not reason being the ultima ratio. Even Euclid, who has laid himself as little open to the charge of credulity as any writer who ever lived, cannot get beyond this. He has no demonstrable first premise. He requires postulates and axioms which transcend demonstration, and without which he can do nothing. His superstructure indeed is demonstration, but his ground his faith. Nor again can he get further than telling a man he is a fool if he persists in differing from him. He says “which is absurd,” and declines to discuss the matter further. Faith and authority, therefore, prove to be as necessary for him as for anyone else.

…indeed what reason may not go to Schoole to the wisdome of Bees, Aunts, and Spiders? what wise hand teacheth them to doe what reason cannot teach us? Ruder heads stand amazed at those prodigious pieces of nature, Whales, Elephants, Dromidaries and Camels; these I confesse, are the Colossus and Majestick pieces of her hand; but in these narrow Engines there is more curious Mathematicks, and the civilitie of these little Citizens more neatly sets forth the wisedome of their Maker.

…small, yet they are extremely wise: Ants are creatures of little strength, yet they store up their food in the summer…

…the simplicity, the indispensableness of each word, each letter, each little dash, that among all artists raises the mathematician nearest to the World-creator; it establishes a sublimity which is equalled in no other art,—Something like it exists at most in symphonic music.

“If there are two theories, one simpler man the other, the simpler one is to be preferred.” At first sight this does not seem quite so bad, but a little thought shows that our tendency to prefer the simpler possibility is psychological rather than scientific. It is less trouble to think that way. Experience invariably shows that the more correct a theory becomes, the more complex does it seem. … So this … interpretation of [Ockham’s Razor] is … worthless.

“What makes the desert beautiful,” said the little prince, “is that somewhere it hides a well …”

[1665-06-11] I out of doors a little to show forsooth my new suit, and back again; and in going, saw poor Dr Burnets door shut. But he hath, I hear, gained goodwill among his neighbours; for he discovered it himself first, and caused himself to be shut up of his own accord - which was very handsome.

[1665-08-16] ...Hence to the Exchange, which I have not been a great while. But Lord, how sad a sight it is to see the streets empty of people, and very few upon the Change - jealous of every door that one sees shut up, lest it should be the plague - and about us, two shops in three, if not more, generally shut up. ... It was dark before I could get home; and so land at church-yard stairs, where to my great trouble I met a dead Corps, of the plague, in the narrow ally, just bringing down a little pair of stairs - but I thank God I was not much disturbed at it. However, I shall beware of being late abroad again.

[1665-09-14] ...my finding that although the Bill [total of dead] in general is abated, yet the City within the walls is encreasd and likely to continue so (and is close to our house there) - my meeting dead corps's of the plague, carried to be buried close to me at noonday through the City in Fanchurch-street - to see a person sick of the sores carried close by me by Grace-church in a hackney-coach - my finding the Angell tavern at the lower end of Tower-hill shut up; and more then that, the alehouse at the Tower-stairs; and more then that, that the person was then dying of the plague when I was last there, a little while ago at night, to write a short letter there, and I overheard the mistress of the house sadly saying to her husband somebody was very ill, but did not think it was of the plague - to hear that poor Payne my waterman hath buried a child and is dying himself - to hear that a labourer I sent but the other day to Dagenhams to know how they did there is dead of the plague and that one of my own watermen, that carried me daily, fell sick as soon as he had landed me on Friday morning last, when I had been all night upon the water ... is now dead of the plague - to hear ... that Mr Sidny Mountagu is sick of a desperate fever at my Lady Carteret's at Scott's hall - to hear that Mr. Lewes hath another daughter sick - and lastly, that both my servants, W Hewers and Tom Edwards, have lost their fathers, both in St. Sepulcher's parish, of the plague this week - doth put me into great apprehensions of melancholy, and with good reason. But I put off the thoughts of sadness as much as I can, and the rather to keep my wife in good heart and family also.

[An] old Pythagorean prejudice … thought it a crime to eat eggs; because an egg was a microcosm, or universe in little; the shell being the earth; the white, water; fire, the yolk; and the air found between the shell and the white.

[At the end of the story, its main character, Tom] is now a great man of science, and can plan railroads, and steam-engines, and electric telegraphs, and rifled guns, and so forth; and knows everything about everything, except why a hen's egg don't turn into a crocodile, and two or three other little things that no one will know till the coming of the Cocqcigrues.

[F. Werner, while a student in Princeton,] came to me and expressed his bewilderment with the fact that we make a rather narrow selection when choosing the data on which we test our theories. “How do we know that, if we made a theory which focuses its attention on phenomena we disregard and disregards some of the phenomena now commanding our attention, that we could not build another theory which has little in common with the present one but which, nevertheless, explains just as many phenomena as the present theory?” It has to be admitted that we have no definite evidence that there is no such theory.

[I attach] little importance to physical size. I don’t feel the least humble before the vastness of the heavens. The stars may be large, but they cannot think or love; and these are qualities which impress me far more than size does.

[It] is not the nature of things for any one man to make a sudden, violent discovery; science goes step by step and every man depends on the work of his predecessors. When you hear of a sudden unexpected discovery—a bolt from the blue—you can always be sure that it has grown up by the influence of one man or another, and it is the mutual influence which makes the enormous possibility of scientific advance. Scientists are not dependent on the ideas of a single man, but on the combined wisdom of thousands of men, all thinking of the same problem and each doing his little bit to add to the great structure of knowledge which is gradually being erected.

[It] is the little causes, long continued, which are considered as bringing about the greatest changes of the earth.

[L]et us not overlook the further great fact, that not only does science underlie sculpture, painting, music, poetry, but that science is itself poetic. The current opinion that science and poetry are opposed is a delusion. … On the contrary science opens up realms of poetry where to the unscientific all is a blank. Those engaged in scientific researches constantly show us that they realize not less vividly, but more vividly, than others, the poetry of their subjects. Whoever will dip into Hugh Miller’s works on geology, or read Mr. Lewes's “Seaside Studies,” will perceive that science excites poetry rather than extinguishes it. And whoever will contemplate the life of Goethe will see that the poet and the man of science can co-exist in equal activity. Is it not, indeed, an absurd and almost a sacrilegious belief that the more a man studies Nature the less he reveres it? Think you that a drop of water, which to the vulgar eye is but a drop of water, loses anything in the eye of the physicist who knows that its elements are held together by a force which, if suddenly liberated, would produce a flash of lightning? Think you that what is carelessly looked upon by the uninitiated as a mere snow-flake, does not suggest higher associations to one who has seen through a microscope the wondrously varied and elegant forms of snow-crystals? Think you that the rounded rock marked with parallel scratches calls up as much poetry in an ignorant mind as in the mind of a geologist, who knows that over this rock a glacier slid a million years ago? The truth is, that those who have never entered upon scientific pursuits know not a tithe of the poetry by which they are surrounded. Whoever has not in youth collected plants and insects, knows not half the halo of interest which lanes and hedge-rows can assume. Whoever has not sought for fossils, has little idea of the poetical associations that surround the places where imbedded treasures were found. Whoever at the seaside has not had a microscope and aquarium, has yet to learn what the highest pleasures of the seaside are. Sad, indeed, is it to see how men occupy themselves with trivialities, and are indifferent to the grandest phenomena—care not to understand the architecture of the Heavens, but are deeply interested in some contemptible controversy about the intrigues of Mary Queen of Scots!—are learnedly critical over a Greek ode, and pass by without a glance that grand epic written by the finger of God upon the strata of the Earth!

[Learning is] the actual process of broadening yourself, of knowing there’s a little extra facet of the universe you know about and can think about and can understand. It seems to me that when it’s time to die, and that will come to all of us, there’ll be a certain pleasure in thinking that you had utilized your life well, that you had learned as much as you could, gathered in as much as possible of the universe, and enjoyed it. I mean, there’s only this universe and only this one lifetime to try to grasp it. And, while it is inconceivable that anyone can grasp more than a tiny portion of it, at least do that much. What a tragedy to just pass through and get nothing out of it.

[Misattributed] A little knowledge is a dangerous thing. So is a lot.

[My study of the universe] leaves little doubt that life has occurred on other planets. I doubt if the human race is the most intelligent form of life.

[Overfishing—] it’s not just that we’re taking too many out, it’s how we’re doing it. We are wiping out their nurseries, … [because some huge boats] … bottom trawl … [with] nets that 50 years ago you’d have to lift when you came to coral reefs or rocks or nooks and crannies. Now they’re so sophisticated and so heavy, the equipment, and the boat’s so powerful they can just drag right over the coral reefs and the rocks and the nooks and crannies, and turn them into a gravel pit. … The trouble is those are the nurseries. That’s where the little fish hide and get bigger and get big enough for us to eat.

[Penguins] are extraordinarily like children, these little people of the Antarctic world, either like children, or like old men, full of their own importance and late for dinner, in their black tail-coats and white shirt-fronts — and rather portly withal.

[Science doesn’t deal with facts; indeed] fact is an emotion-loaded word for which there is little place in scientific debate.

[Scientists are explorers.] Spoke-like, their trails into the unknown leave the little hub of common knowledge far behind and their fellow explorers further and further out of touch.

[T]he idea of protoplasm, which was really a name for our ignorance, [is] only a little less misleading than the expression “Vital force”.

[T]here is little chance that aliens from two societies anywhere in the Galaxy will be culturally close enough to really 'get along.' This is something to ponder as you watch the famous cantina scene in Star Wars. ... Does this make sense, given the overwhelmingly likely situation that galactic civilizations differ in their level of evolutionary development by thousands or millions of years? Would you share drinks with a trilobite, an ourang-outang, or a saber-toothed tiger? Or would you just arrange to have a few specimens stuffed and carted off to the local museum?

[The famous attack of Sir William Hamilton on the tendency of mathematical studies] affords the most express evidence of those fatal lacunae in the circle of his knowledge, which unfitted him for taking a comprehensive or even an accurate view of the processes of the human mind in the establishment of truth. If there is any pre-requisite which all must see to be indispensable in one who attempts to give laws to the human intellect, it is a thorough acquaintance with the modes by which human intellect has proceeded, in the case where, by universal acknowledgment, grounded on subsequent direct verification, it has succeeded in ascertaining the greatest number of important and recondite truths. This requisite Sir W. Hamilton had not, in any tolerable degree, fulfilled. Even of pure mathematics he apparently knew little but the rudiments. Of mathematics as applied to investigating the laws of physical nature; of the mode in which the properties of number, extension, and figure, are made instrumental to the ascertainment of truths other than arithmetical or geometrical—it is too much to say that he had even a superficial knowledge: there is not a line in his works which shows him to have had any knowledge at all.

[To one of his students he saw in a school dramatic production:] I’ve always been proud that Course X leaves little time for outside activities. You have proved me wrong so far and I’m glad you have. But don’t push your luck too far!

[To the cultures of Asia and the continent of Africa] it is the Western impact which has stirred up the winds of change and set the processes of modernization in motion. Education brought not only the idea of equality but also another belief which we used to take for granted in the West—the idea of progress, the idea that science and technology can be used to better human conditions. In ancient society, men tended to believe themselves fortunate if tomorrow was not worse than today and anyway, there was little they could do about it.

[When I was a child] I grew up in Brooklyn, New York, and I was a street kid. … [T]here was one aspect of that environment that, for some reason, struck me as different, and that was the stars. … I could tell they were lights in the sky, but that wasn’t an explanation. I mean, what were they? Little electric bulbs on long black wires, so you couldn’t see what they were held up by? What were they? … My mother said to me, "Look, we’ve just got you a library card … get out a book and find the answer.” … It was in there. It was stunning. The answer was that the Sun was a star, except very far away. … The dazzling idea of a universe vast beyond imagining swept over me. … I sensed awe.

Boss: I just heard that light travels faster than sound. I'm wondering if I should shout when I speak, just so my lips appear to sync-up with my words.
Dilbert (thought): A little knowledge can be a ridiculous thing.

Ces détails scientifiques qui effarouchent les fabricans d’un certain âge, ne seront qu’un jeu pour leurs enfans, quand ils auront apprit dans leurs collèges un peu plus de mathématiques et un peu moins de Latin; un peu plus de Chimie, et un peu moins de Grec!
The scientific details which now terrify the adult manufacturer will be mere trifles to his children when they shall be taught at school, a little more Mathematics and a little less Latin, a little more Chemistry, and a little less Greek.

Clarke's Second Law: The only way of discovering the limits of the possible is to venture a little way past them into the impossible.

Dilbert: It took weeks but I’ve calculated a new theory about the origin of the universe. According to my calculations it didn’t start with a “Big Bang” at all—it was more of “Phhbwt” sound. You may be wondering about the practical applications of the “Little Phhbwt” theory.
Dogbert: I was wondering when you’ll go away.

Error of confounding cause and effect.—There is no more dangerous error than confounding consequence with cause: I call it the intrinsic depravity of reason. … I take an example: everybody knows the book of the celebrated Comaro, in which he recommends his spare diet as a recipe for a long and happy life,—for a virtuous life also. Few books have been read so much… I believe hardly any book … has caused so much harm, has shortened so many lives, as this well-meant curiosity. The source of this mischief is in confounding consequence with cause. The candid Italian saw in his diet the cause of his long life, while the prerequisite to long life, the extraordinary slowness of the metabolic process, small consumption, was the cause of his spare diet. He was not at liberty to eat little or much; his frugality—was not of “free will;” he became sick when he ate more.

Every teacher certainly should know something of non-euclidean geometry. Thus, it forms one of the few parts of mathematics which, at least in scattered catch-words, is talked about in wide circles, so that any teacher may be asked about it at any moment. … Imagine a teacher of physics who is unable to say anything about Röntgen rays, or about radium. A teacher of mathematics who could give no answer to questions about non-euclidean geometry would not make a better impression.
On the other hand, I should like to advise emphatically against bringing non-euclidean into regular school instruction (i.e., beyond occasional suggestions, upon inquiry by interested pupils), as enthusiasts are always recommending. Let us be satisfied if the preceding advice is followed and if the pupils learn to really understand euclidean geometry. After all, it is in order for the teacher to know a little more than the average pupil.

Goldsmith: If you put a tub full of blood into a stable, the horses are like to go mad.
Johnson: I doubt that.
Goldsmith: Nay, sir, it is a fact well authenticated.
Thrale: You had better prove it before you put it into your book on natural history. You may do it in my stable if you will.
Johnson: Nay, sir, I would not have him prove it. If he is content to take his information from others, he may get through his book with little trouble, and without much endangering his reputation. But if he makes experiments for so comprehensive a book as his, there would be no end to them; his erroneous assertions would then fall upon himself: and he might be blamed for not having made experiments as to every particular.

If the Indians hadn’t spent the $24. In 1626 Peter Minuit, first governor of New Netherland, purchased Manhattan Island from the Indians for about $24. … Assume for simplicity a uniform rate of 7% from 1626 to the present, and suppose that the Indians had put their $24 at [compound] interest at that rate …. What would be the amount now, after 280 years? 24 x (1.07)280 = more than 4,042,000,000.
The latest tax assessment available at the time of writing gives the realty for the borough of Manhattan as $3,820,754,181. This is estimated to be 78% of the actual value, making the actual value a little more than $4,898,400,000.
The amount of the Indians’ money would therefore be more than the present assessed valuation but less than the actual valuation.

L’homme n’est qu’un roseau, le plus faible de la nature, mais c’est un roseau pensant. Il ne faut pas que l’univers entier s’arme pour l’écraser; une vapeur, une goutte d’eau suffit pour le tuer. Mais quand l’univers l’écraserait, l’homme serait encore plus noble que ce qui le tue, parce qu’il sait qu’il meurt et l’avantage que l’univers a sur lui; l’univers n'en sait rien.
Man is a reed, the feeblest thing in nature. But a reed that can think. The whole universe need not fly to arms to kill him ; for a little heat or a drop of water can slay a man. But, even then, man would be nobler than his destroyer, for he would know he died, while the whole universe would know nothing of its victory.

La vérité ne diffère de l'erreur qu'en deux points: elle est un peu plus difficile à prouver et beaucoup plus difficile à faire admettre. (Dec 1880)
Truth is different from error in two respects: it is a little harder to prove and more difficult to admit.

Lepidoptera are for children to play with, pretty to look at, so some think. Give me the Coleoptera, and the kings of the Coleoptera are the beetles! Lepidoptera and Neuroptera for little folks; Coleoptera for men, sir!

Nature is curious, and such worke may make,
That our dull sense can never finde, but scape.
For Creatures, small as Atomes, may be there,
If every Atome a Creatures Figure beare.
If foure Atomes a World can make, then see
What severall Worlds might in an Eare--ring bee:
For Millions of these Atomes may bee in
The Head of one Small, little, Single Pin.
And if thus Small, then Ladies may well weare
A World of Worlds, as Pendents in each Eare.

Puisqu'on ne peut être universel en sachant tout ce qui se peut sur tout, il faut savoir peu de tout. Car il est bien plus beau de savoir quelque chose de tout que de savoir rout d'une chose; cette universalité est la plus belle. Si on pouvait avoir les deux, encore mieux.
Since we cannot be universal and know all that is to be known of everything, we ought to know a little about everything, For it is far better to know something about everything than to know all about one thing.

Qu'une goutee de vin tombe dans un verre d'eau; quelle que soit la loi du movement interne du liquide, nous verrons bientôt se colorer d'une teinte rose uniforme et à partir de ce moment on aura beau agiter le vase, le vin et l'eau ne partaîtront plus pouvoir se séparer. Tout cela, Maxwell et Boltzmann l'ont expliqué, mais celui qui l'a vu plus nettement, dans un livre trop peu lu parce qu'il est difficile à lire, c'est Gibbs dans ses principes de la Mécanique Statistique.
Let a drop of wine fall into a glass of water; whatever be the law that governs the internal movement of the liquid, we will soon see it tint itself uniformly pink and from th at moment on, however we may agitate the vessel, it appears that the wine and water can separate no more. All this, Maxwell and Boltzmann have explained, but the one who saw it in the cleanest way, in a book that is too little read because it is difficult to read, is Gibbs, in his Principles of Statistical Mechanics.

Qui ergo munitam vult habere navem habet etiam acum jaculo suppositam. Rotabitur enim et circumvolvetur acus, donec cuspis acus respiciat orientem sicque comprehendunt quo tendere debeant nautaw cum Cynosura latet in aeris turbatione; quamvis ad occasum numquam tendat, propter circuli brevitatem.
If then one wishes a ship well provided with all things, then one must have also a needle mounted on a dart. The needle will be oscillated and turn until the point of the needle directs itself to the East* [North], thus making known to sailors the route which they should hold while the Little Bear is concealed from them by the vicissitudes of the atmosphere; for it never disappears under the horizon because of the smallness of the circle it describes.

The Water-baby story character, Tom, asks: 'I heard, ma'am, that you were always making new beasts out of old.'
Mother Carey [Mother Nature] replies: 'So people fancy. But I am not going to trouble myself to make things, my little dear. I sit here and make them make themselves.'
[The author's indirect reference to evolution.]

Third Fisherman: Master, I marvel how the fishes live in the sea.
First Fisherman: Why, as men do a-land; the great ones eat up the little ones: I can compare our rich misers to nothing so fitly as to a whale; a’ plays and tumbles, driving the poor fry before him, and at last devours them all at a mouthful: such whales have I heard on o’ the land, who never leave gaping till they’ve swallowed the whole parish, church, steeple, bells, and all.

Trimming consists of clipping off little bits here and there from those observations which differ most in excess from the mean, and in sticking them onto those which are too small; a species of 'equitable adjustment,' as a radical would term it, which cannot be admitted in science.

~~[Unverified]~~ Why has elegance found so little following? Elegance has the disadvantage that hard work is needed to achieve it and a good education to appreciate it.

A little Learning is a dang’rous Thing;
Drink deep, or taste not the Pierian Spring:
There shallow Draughts intoxicate the Brain,
And drinking largely sobers us again.

A casual glance at crystals may lead to the idea that they were pure sports of nature, but this is simply an elegant way of declaring one’s ignorance. With a thoughtful examination of them, we discover laws of arrangement. With the help of these, calculation portrays and links up the observed results. How variable and at the same time how precise and regular are these laws! How simple they are ordinarily, without losing anything of their significance! The theory which has served to develop these laws is based entirely on a fact, whose existence has hitherto been vaguely discerned rather than demonstrated. This fact is that in all minerals which belong to the same species, these little solids, which are the crystal elements and which I call their integrant molecules, have an invariable form, in which the faces lie in the direction of the natural fracture surfaces corresponding to the mechanical division of the crystals. Their angles and dimensions are derived from calculations combined with observation.

A crystal is like a class of children arranged for drill, but standing at ease, so that while the class as a whole has regularity both in time and space, each individual child is a little fidgety!

A foolish consistency is the hobgoblin of little minds, adored by little statesmen and philosophers and divines.

A frequent misunderstanding of my vision of Gaia is that I champion complacence, that I claim feedback will always protect the environment from any serious harm that humans might do. It is sometimes more crudely put as “Lovelock’s Gaia gives industry the green light to pollute at will.” The truth is almost diametrically opposite. Gaia, as I see her, is no doting mother tolerant of misdemeanors, nor is she some fragile and delicate damsel in danger from brutal mankind. She is stern and tough, always keeping the world warm and comfortable for those who obey the rules, but ruthless in her destruction of those who transgress. Her unconscious goal is a planet fit for life. If humans stand in the way of this, we shall be eliminated with as little pity as would be shown by the micro-brain of an intercontinental ballistic nuclear missile in full flight to its target.

A human without a cosmology is like a pebble lying near the top of a great mountain, in contact with its little indentation in the dirt and pebbles immediately surrounding it, but oblivious to its stupendous view.

A little knowledge is dangerous. So is a lot.

A little learning is a dangerous thing;—not if you know how little it is.

A little science is something that they must have. I should like my nephews to know what air is, and water; why we breathe, and why wood burns; the nutritive elements essential to plant life, and the constituents of the soil. And it is no vague and imperfect knowledge from hearsay I would have them gain of these fundamental truths, on which depend agriculture and the industrial arts and our health itself; I would have them know these things thoroughly from their own observation and experience. Books here are insufficient, and can serve merely as aids to scientific experiment.

A man who writes a great deal and says little that is new writes himself into a daily declining reputation. When he wrote less he stood higher in people’s estimation, even though there was nothing in what he wrote. The reason is that then they still expected better things of him in the future, whereas now they can view the whole progression.

A man, as a general rule, owes very little to what he is born with—a man is what he makes of himself.

A marine protozoan is an aqueous salty system in an aqueous salty medium, but a man is an aqueous salty system in a medium in which there is but little water and most of that poor in salts.

A noiseless, patient spider,
I mark’d, where on a little promontory, it stood, isolated;
Mark’d how, to explore the vacant, vast surrounding,
It launch’d forth filament, filament, filament, out of itself
Ever unreeling them—ever tirelessly speeding them.

A paranoid man is a man who knows a little about what’s going on.

A scientist strives to understand the work of Nature. But with our insufficient talents as scientists, we do not hit upon the truth all at once. We must content ourselves with tracking it down, enveloped in considerable darkness, which leads us to make new mistakes and errors. By diligent examination, we may at length little by little peel off the thickest layers, but we seldom get the core quite free, so that finally we have to be satisfied with a little incomplete knowledge.

A smattering of everything is worth little. It is a fallacy to suppose that an encyclopaedic knowledge is desirable. The mind is made strong, not through much learning, but by the thorough possession of something.

A surgeon should give as little pain as possible while he is treating the patient, and no pain at all when he charges his fee.

A thesis has to be presentable… but don't attach too much importance to it. If you do succeed in the sciences, you will do later on better things and then it will be of little moment. If you don’t succeed in the sciences, it doesn’t matter at all.

A week or so after I learned that I was to receive the Miller Award, our president, Marty Morton, phoned and asked me if I would utter a few words of scientific wisdom as a part of the ceremony. Unfortunately for me, and perhaps for you, I agreed to do so. In retrospect I fear that my response was a serious error, because I do not feel wise. I do not know whether to attribute my response to foolhardiness, to conceit, to an inordinate susceptibility to flattery, to stupidity, or to some combination of these unfortunate attributes all of which I have been told are recognizable in my personality. Personally, I tend to favor stupidity, because that is a condition over which I have little control.

A wise system of education will at least teach us how little man yet knows, how much he has still to learn.

About 6 or 8 years ago My Ingenious friend Mr John Robinson having [contrived] conceived that a fire engine might be made without a Lever—by Inverting the Cylinder & placing it above the mouth of the pit proposed to me to make a model of it which was set about by having never Compleated & I [being] having at that time Ignorant little knoledge of the machine however I always thought the Machine Might be applied to [more] other as valuable purposes [than] as drawing Water.

According to the theory of aerodynamics, as may be readily demonstrated through wind tunnel experiments, the bumblebee is unable to fly. This is because the size, weight and shape of his body in relation to the total wingspread make flying impossible. But the bumblebee, being ignorant of these scientific truths, goes ahead and flies anyway—and makes a little honey every day.

Adam is fading out. It is on account of Darwin and that crowd. I can see that he is not going to last much longer. There's a plenty of signs. He is getting belittled to a germ—a little bit of a speck that you can't see without a microscope powerful enough to raise a gnat to the size of a church. They take that speck and breed from it: first a flea; then a fly, then a bug, then cross these and get a fish, then a raft of fishes, all kinds, then cross the whole lot and get a reptile, then work up the reptiles till you've got a supply of lizards and spiders and toads and alligators and Congressmen and so on, then cross the entire lot again and get a plant of amphibiums, which are half-breeds and do business both wet and dry, such as turtles and frogs and ornithorhyncuses and so on, and cross-up again and get a mongrel bird, sired by a snake and dam'd by a bat, resulting in a pterodactyl, then they develop him, and water his stock till they've got the air filled with a million things that wear feathers, then they cross-up all the accumulated animal life to date and fetch out a mammal, and start-in diluting again till there's cows and tigers and rats and elephants and monkeys and everything you want down to the Missing Link, and out of him and a mermaid they propagate Man, and there you are! Everything ship-shape and finished-up, and nothing to do but lay low and wait and see if it was worth the time and expense.

Adam, the first man, didn’t know anything about the nucleus but Dr. George Gamow, visiting professor from George Washington University, pretends he does. He says for example that the nucleus is 0.00000000000003 feet in diameter. Nobody believes it, but that doesn't make any difference to him.
He also says that the nuclear energy contained in a pound of lithium is enough to run the United States Navy for a period of three years. But to get this energy you would have to heat a mixture of lithium and hydrogen up to 50,000,000 degrees Fahrenheit. If one has a little stove of this temperature installed at Stanford, it would burn everything alive within a radius of 10,000 miles and broil all the fish in the Pacific Ocean.
If you could go as fast as nuclear particles generally do, it wouldn’t take you more than one ten-thousandth of a second to go to Miller's where you could meet Gamow and get more details.

After having produced aquatic animals of all ranks and having caused extensive variations in them by the different environments provided by the waters, nature led them little by little to the habit of living in the air, first by the water's edge and afterwards on all the dry parts of the globe. These animals have in course of time been profoundly altered by such novel conditions; which so greatly influenced their habits and organs that the regular gradation which they should have exhibited in complexity of organisation is often scarcely recognisable.

After some experiments made one day at my house upon the phosphorus, a little piece of it being left negligently upon the table in my chamber, the maid making the bed took it up in the bedclothes she had put on the table, not seeing the little piece. The person who lay afterwards in the bed, waking at night and feeling more than ordinary heat, perceived that the coverlet was on fire.

Again there is another great and powerful cause why the sciences have made but little progress; which is this. It is not possible to run a course aright when the goal itself has not been rightly placed.

Alexander the king of the Macedonians, began like a wretch to learn geometry, that he might know how little the earth was, whereof he had possessed very little. Thus, I say, like a wretch for this, because he was to understand that he did bear a false surname. For who can be great in so small a thing? Those things that were delivered were subtile, and to be learned by diligent attention: not which that mad man could perceive, who sent his thoughts beyond the ocean sea. Teach me, saith he, easy things. To whom his master said: These things be the same, and alike difficult unto all. Think thou that the nature of things saith this. These things whereof thou complainest, they are the same unto all: more easy things can be given unto none; but whosoever will, shall make those things more easy unto himself. How? With uprightness of mind.

All frescoes are as high finished as miniatures or enamels, and they are known to be unchangeable; but oil, being a body itself, will drink or absorb very little colour, and changing yellow, and at length brown, destroys every colour it is mixed with, especially every delicate colour. It turns every permanent white to a yellow and brown putty, and has compelled the use of that destroyer of colour, white lead, which, when its protecting oil is evaporated, will become lead again. This is an awful thing to say to oil painters ; they may call it madness, but it is true. All the genuine old little pictures, called cabinet pictures, are in fresco and not in oil. Oil was not used except by blundering ignorance till after Vandyke’s time ; but the art of fresco painting being lost, oil became a fetter to genius and a dungeon to art.

All palaetiological sciences, all speculations which attempt to ascend from the present to the remote past, by the chain of causation, do also, by an inevitable consequence, urge us to look for the beginning of the state of things which we thus contemplate; but in none of these cases have men been able, by the aid of science, to arrive at a beginning which is homogeneous with the known course of events. The first origin of language, of civilization, of law and government, cannot be clearly made out by reasoning and research; and just as little, we may expect, will a knowledge of the origin of the existing and extinct species of plants and animals, be the result of physiological and geological investigation.

All rivers, small or large, agree in one character; they like to lean a little on one side; they cannot bear to have their channels deepest in the middle, but will always, if they can, have one bank to sun themselves upon, and another to get cool under.

All science is full of statements where you put your best face on your ignorance, where you say: … we know awfully little about this, but more or less irrespective of the stuff we don’t know about, we can make certain useful deductions.

All things are made of atoms—little particles that move around in perpetual motion, attracting each other when they are a little distance apart, but repelling upon being squeezed into one another. In that one sentence ... there is an enormous amount of information about the world.
His suggestion that the most valuable information on scientific knowledge in a single sentence using the fewest words is to state the atomic hypothesis.

Although I was four years at the University [of Wisconsin], I did not take the regular course of studies, but instead picked out what I thought would be most useful to me, particularly chemistry, which opened a new world, mathematics and physics, a little Greek and Latin, botany and and geology. I was far from satisfied with what I had learned, and should have stayed longer.
[Enrolled in Feb 1861, left in 1863 without completing a degree, and began his first botanical foot journey.]

Alvarez seemed to care less about the way the picture in the puzzle would look, when everything fit together, than about the fun of looking for pieces that fit. He loved nothing more than doing something that everybody else thought impossible. His designs were clever, and usually exploited some little-known principle that everyone else had forgotten.

Always preoccupied with his profound researches, the great Newton showed in the ordinary-affairs of life an absence of mind which has become proverbial. It is related that one day, wishing to find the number of seconds necessary for the boiling of an egg, he perceived, after waiting a minute, that he held the egg in his hand, and had placed his seconds watch (an instrument of great value on account of its mathematical precision) to boil!
This absence of mind reminds one of the mathematician Ampere, who one day, as he was going to his course of lectures, noticed a little pebble on the road; he picked it up, and examined with admiration the mottled veins. All at once the lecture which he ought to be attending to returned to his mind; he drew out his watch; perceiving that the hour approached, he hastily doubled his pace, carefully placed the pebble in his pocket, and threw his watch over the parapet of the Pont des Arts.

Among the memoirs of Kirchhoff are some of uncommon beauty. … Can anything be beautiful, where the author has no time for the slightest external embellishment?—But—; it is this very simplicity, the indispensableness of each word, each letter, each little dash, that among all artists raises the mathematician nearest to the World-creator; it establishes a sublimity which is equalled in no other art, something like it exists at most in symphonic music. The Pythagoreans recognized already the similarity between the most subjective and the most objective of the arts.

Ampère was a mathematician of various resources & I think might rather be called excentric [sic] than original. He was as it were always mounted upon a hobby horse of a monstrous character pushing the most remote & distant analogies. This hobby horse was sometimes like that of a child ['s] made of heavy wood, at other times it resembled those [?] shapes [?] used in the theatre [?] & at other times it was like a hypogrif in a pantomime de imagie. He had a sort of faith in animal magnetism & has published some refined & ingenious memoirs to prove the identity of electricity & magnetism but even in these views he is rather as I said before excentric than original. He has always appeared to me to possess a very discursive imagination & but little accuracy of observation or acuteness of research.

An enthusiastic philosopher, of whose name we are not informed, had constructed a very satisfactory theory on some subject or other, and was not a little proud of it. “But the facts, my dear fellow,” said his friend, “the facts do not agree with your theory.”—“Don't they?” replied the philosopher, shrugging his shoulders, “then, tant pis pour les faits;”—so much the worse for the facts!

An idea must not be condemned for being a little shy and incoherent; all new ideas are shy when introduced first among our old ones. We should have patience and see whether the incoherency is likely to wear off or to wear on, in which latter case the sooner we get rid of them the better.

An idea must not be condemned for being a little shy and incoherent; all new ideas are shy when introduced first among our old ones. We should have patience and see whether the incoherency is likely to wear off or to wear on, in which latter case the sooner we get rid of them the better.

An incidental remark from a German colleague illustrates the difference between Prussian ways and our own. He had apparently been studying the progress of our various crews on the river, and had been struck with the fact that though the masters in charge of the boats seemed to say and do very little, yet the boats went continually faster and faster, and when I mentioned Dr. Young’s book to him, he made the unexpected but suggestive reply: “Mathematics in Prussia! Ah, sir, they teach mathematics in Prussia as you teach your boys rowing in England: they are trained by men who have been trained by men who have themselves been trained for generations back.”

An increase in knowledge acquired too quickly and with too little participation on one’s own part is not very fruitful: erudition can produce foliage without bearing fruit.

Anatomy is the great ocean of intelligence upon which the true physician must sail. Bacteriology is but one little harbor.

And I do not take my medicines from the apothecaries; their shops are but foul sculleries, from which comes nothing but foul broths. As for you, you defend your kingdom with belly-crawling and flattery. How long do you think this will last? ... let me tell you this: every little hair on my neck knows more than you and all your scribes, and my shoebuckles are more learned than your Galen and Avicenna, and my beard has more experience than all your high colleges.

And if one look through a Prism upon a white Object encompassed with blackness or darkness, the reason of the Colours arising on the edges is much the same, as will appear to one that shall a little consider it. If a black Object be encompassed with a white one, the Colours which appear through the Prism are to be derived from the Light of the white one, spreading into the Regions of the black, and therefore they appear in a contrary order to that, when a white Object is surrounded with black. And the same is to be understood when an Object is viewed, whose parts are some of them less luminous than others. For in the borders of the more and less luminous Parts, Colours ought always by the same Principles to arise from the Excess of the Light of the more luminous, and to be of the same kind as if the darker parts were black, but yet to be more faint and dilute.

And no one has the right to say that no water-babies exist, till they have seen no water-babies existing; which is quite a different thing, mind, from not seeing water-babies; and a thing which nobody ever did, or perhaps will ever do. But surely [if one were caught] ... they would have put it into spirits, or into the Illustrated News, or perhaps cut it into two halves, poor dear little thing, and sent one to Professor Owen, and one to Professor Huxley, to see what they would each say about it.

Any one who has studied the history of science knows that almost every great step therein has been made by the “anticipation of Nature,” that is, by the invention of hypotheses, which, though verifiable, often had very little foundation to start with; and, not unfrequently, in spite of a long career of usefulness, turned out to be wholly erroneous in the long run.

Any one, if he will only observe, can find some little thing he does not understand as a starter for an investigation.

Anyone who sits on top of the largest hydrogen-oxygen fueled system in the world; knowing they’re going to light the bottom, and doesn’t get a little worried, does not fully understand the situation.

Are we using science in ways that it wasn't intended to, in which case we should be a little careful, or are we using faith in ways that faith wasn't really designed for? There are certain questions that are better answered by one approach than the other, and if you start mixing that up, then you end up in … conflict.

Art thou the bird whom Man loves best,
The pious bird with the scarlet breast,
Our little English Robin;
The bird that comes about our doors
When autumn winds are sobbing?

As a little boy, I showed an abnormal aptitude for mathematics this gift played a horrible part in tussles with quinsy or scarlet fever, when I felt enormous spheres and huge numbers swell relentlessly in my aching brain.

As arithmetic and algebra are sciences of great clearness, certainty, and extent, which are immediately conversant about signs, upon the skilful use whereof they entirely depend, so a little attention to them may possibly help us to judge of the progress of the mind in other sciences, which, though differing in nature, design, and object, may yet agree in the general methods of proof and inquiry.

As each bit of information is added to the sum of human knowledge it is evident that it is the little things that count; that give all the fertility and character; that give all the hope and happiness to human affairs. The concept of bigness is apt to be a delusion, and standardizing processes must not supplant creative impulses.

As for the excellent little wretches who grow up in what they are taught, with never a scruple or a query, ... they signify nothing in the intellectual life of the race.

As for what I have done as a poet, I take no pride in whatever. Excellent poets have lived at the same time with me, poets more excellent lived before me, and others will come after me. But that in my country I am the only person who knows the truth in the difficult science of colors—of that, I say, I am not a little proud, and here have a consciousness of superiority to many.

As I stood behind the coffin of my little son the other day, with my mind bent on anything but disputation, the officiating minister read, as part of his duty, the words, 'If the dead rise not again, let us eat and drink, for to-morrow we die.' I cannot tell you how inexpressibly they shocked me. Paul had neither wife nor child, or he must have known that his alternative involved a blasphemy against all that well best and noblest in human nature. I could have laughed with scorn. What! Because I am face to face with irreparable loss, because I have given back to the source from whence it came, the cause of a great happiness, still retaining through all my life the blessings which have sprung and will spring from that cause, I am to renounce my manhood, and, howling, grovel in bestiality? Why, the very apes know better, and if you shoot their young, the poor brutes grieve their grief out and do not immediately seek distraction in a gorge.

As regards authority I so proceed. Boetius says in the second prologue to his Arithmetic, “If an inquirer lacks the four parts of mathematics, he has very little ability to discover truth.” And again, “Without this theory no one can have a correct insight into truth.” And he says also, “I warn the man who spurns these paths of knowledge that he cannot philosophize correctly.” And Again, “It is clear that whosoever passes these by, has lost the knowledge of all learning.”

As the nineteenth century drew to a close, scientists could reflect with satisfaction that they had pinned down most of the mysteries of the physical world: electricity, magnetism, gases, optics, acoustics, kinetics and statistical mechanics … all had fallen into order before them. They had discovered the X ray, the cathode ray, the electron, and radioactivity, invented the ohm, the watt, the Kelvin, the joule, the amp, and the little erg.

Astronomy is a cold, desert science, with all its pompous figures,—depends a little too much on the glass-grinder, too little on the mind. ’Tis of no use to show us more planets and systems. We know already what matter is, and more or less of it does not signify.

Astronomy teaches the correct use of the sun and the planets. These may be put on a frame of little sticks and turned round. This causes the tides. Those at the ends of the sticks are enormously far away. From time to time a diligent searching of the sticks reveals new planets. The orbit of the planet is the distance the stick goes round in going round. Astronomy is intensely interesting; it should be done at night, in a high tower at Spitzbergen. This is to avoid the astronomy being interrupted. A really good astronomer can tell when a comet is coming too near him by the warning buzz of the revolving sticks.

Astrophysicists have the formidable privilege of having the largest view of the Universe; particle detectors and large telescopes are today used to study distant stars, and throughout space and time, from the infinitely large to the infinitely small, the Universe never ceases to surprise us by revealing its structures little by little.

At Gabriel College there was a very holy object on the high altar of the Oratory, covered with a black velvet cloth... At the height of the invocation the Intercessor lifted the cloth to reveal in the dimness a glass dome inside which there was something too distant to see, until he pulled a string attached to a shutter above, letting a ray of sunlight through to strike the dome exactly. Then it became clear: a little thing like a weathervane, with four sails black on one side and white on the other, began to whirl around as the light struck it. It illustrated a moral lesson, the Intercessor explained, for the black of ignorance fled from the light, whereas the wisdom of white rushed to embrace it.
[Alluding to Crookes's radiometer.]

At length being at Clapham where there is, on the common, a large pond which, I observed to be one day very rough with the wind, I fetched out a cruet of oil and dropt a little of it on the water. I saw it spread itself with surprising swiftness upon the surface; but the effect of smoothing the waves was not produced; for I had applied it first on the leeward side of the pond, where the waves were largest, and the wind drove my oil back upon the shore. I then went to the windward side, where they began to form; and there the oil, though not more than a tea-spoonful, produced an instant calm over a space several yards square, which spread amazingly, and extended itself gradually till it reached the leeside, making all that quarter of the pond, perhaps half an acre, as smooth as a looking-glass.
[Experiment to test an observation made at sea in 1757, when he had seen the wake of a ship smoothed, explained by the captain as presumably due to cooks emptying greasy water in to the sea through the scuppers.]

At the end of the book [Zoonomia] he sums up his [Erasmus Darwin] views in the following sentences: “The world has been evolved, not created: it has arisen little by little from a small beginning, and has increased through the activity of the elemental forces embodied in itself, and so has rather grown than come into being at an almighty word.” “What a sublime idea of the infinite might of the great Architect, the Cause of all causes, the Father of all fathers, the Ens Entium! For if we would compare the Infinite, it would surely require a greater Infinite to cause the causes of effects than to produce the effects themselves.”
[This is a restatement, not a verbatim quote of the original words of Erasmus Darwin, who attributed the idea he summarized to David Hume.]

Before any great scientific principle receives distinct enunciation by individuals, it dwells more or less clearly in the general scientific mind. The intellectual plateau is already high, and our discoverers are those who, like peaks above the plateau, rise a little above the general level of thought at the time.

Between prosperity and adversity there can be little real fellowship.

Big whorls have little whorls
Which feed on their velocity
And little whorls have lesser whorls,
And so on to viscosity.
[Concerning atmospheric turbulence.]

Biological disciplines tend to guide research into certain channels. One consequence is that disciplines are apt to become parochial, or at least to develop blind spots, for example, to treat some questions as “interesting” and to dismiss others as “uninteresting.” As a consequence, readily accessible but unworked areas of genuine biological interest often lie in plain sight but untouched within one discipline while being heavily worked in another. For example, historically insect physiologists have paid relatively little attention to the behavioral and physiological control of body temperature and its energetic and ecological consequences, whereas many students of the comparative physiology of terrestrial vertebrates have been virtually fixated on that topic. For the past 10 years, several of my students and I have exploited this situation by taking the standard questions and techniques from comparative vertebrate physiology and applying them to insects. It is surprising that this pattern of innovation is not more deliberately employed.

Break the chains of your prejudices and take up the torch of experience, and you will honour nature in the way she deserves, instead of drawing derogatory conclusions from the ignorance in which she has left you. Simply open your eyes and ignore what you cannot understand, and you will see that a labourer whose mind and knowledge extend no further than the edges of his furrow is no different essentially from the greatest genius, as would have been proved by dissecting the brains of Descartes and Newton; you will be convinced that the imbecile or the idiot are animals in human form, in the same way as the clever ape is a little man in another form; and that, since everything depends absolutely on differences in organisation, a well-constructed animal who has learnt astronomy can predict an eclipse, as he can predict recovery or death when his genius and good eyesight have benefited from some time at the school of Hippocrates and at patients' bedsides.

Buffon, who, with all his theoretical ingenuity and extraordinary eloquence, I suspect had little actual information in the science on which he wrote so admirably For instance, he tells us that the cow sheds her horns every two years; a most palpable error. ... It is wonderful that Buffon who lived so much in the country at his noble seat should have fallen into such a blunder I suppose he has confounded the cow with the deer.

But as the wilderness areas are progressively exploited or “improve”, as the jeeps and bulldozers of uranium prospectors scar up the deserts and the roads are cut into the alpine timberlands, and as the remnants of the unspoiled and natural world are progressively eroded, every such loss is a little death in me. In us.

But by far the greatest hindrance and aberration of the human understanding proceeds from the dullness, incompetency, and deceptions of the senses; in that things which strike the sense outweigh things which do not immediately strike it, though they be more important. Hence it is that speculation commonly ceases where sight ceases; insomuch that of things invisible there is little or no observation.

But for twenty years previous to 1847 a force had been at work in a little county town of Germany destined to effect the education of Christendom, and at the same time to enlarge the boundaries of human knowledge, first in chemistry and the allied branches, then in every other one of the natural sciences. The place was Giessen; the inventor Liebig; the method, a laboratory for instruction and research.

But in my opinion we can now be assured sufficiently that no animals, however small they may be, take their origin in putrefaction, but exclusively in procreation… For seeing that animals, from the largest down to the little despised animal, the flea, have animalcules in their semen, seeing also that some of the vessels of the lungs of horses and cows consist of rings and that these rings can occur on the flea's veins, why cannot we come to the conclusion that as well as the male sperm of that large animal the horse and similar animals, and of all manner of little animals, the flea included, is furnished with animalcules (and other intestines, for I have often been astonished when I beheld the numerous vessels in a flea), why, I say should not the male sperm of the smallest animals, smaller than a flea may even the very smallest animalcules have the perfection that we find in a flea.

But many of our imaginations and investigations of nature are futile, especially when we see little living animals and see their legs and must judge the same to be ten thousand times thinner than a hair of my beard, and when I see animals living that are more than a hundred times smaller and am unable to observe any legs at all, I still conclude from their structure and the movements of their bodies that they do have legs... and therefore legs in proportion to their bodies, just as is the case with the larger animals upon which I can see legs... Taking this number to be about a hundred times smaller, we therefore find a million legs, all these together being as thick as a hair from my beard, and these legs, besides having the instruments for movement, must be provided with vessels to carry food.

But nothing ever put 'Hoppy' in the shade. No one could fail to recognize in the little figure... the authentic gold of intellectual inspiration, the Fundator et Primus Abbas of biochemistry in England.
Co-author with D. M. Needham,

But nothing of a nature foreign to the duties of my profession [clergyman] engaged my attention while I was at Leeds so much as the, prosecution of my experiments relating to electricity, and especially the doctrine of air. The last I was led into a consequence of inhabiting a house adjoining to a public brewery, where first amused myself with making experiments on fixed air [carbon dioxide] which found ready made in the process of fermentation. When I removed from that house, I was under the necessity making the fixed air for myself; and one experiment leading to another, as I have distinctly and faithfully noted in my various publications on the subject, I by degrees contrived a convenient apparatus for the purpose, but of the cheapest kind. When I began these experiments I knew very little of chemistry, and had in a manner no idea on the subject before I attended a course of chymical lectures delivered in the Academy at Warrington by Dr. Turner of Liverpool. But I have often thought that upon the whole, this circumstance was no disadvantage to me; as in this situation I was led to devise an apparatus and processes of my own, adapted to my peculiar views. Whereas, if I had been previously accustomed to the usual chemical processes, I should not have so easily thought of any other; and without new modes of operation I should hardly have discovered anything materially new.