[My advice] will one day be found
With other relics of 'a former world,'
When this world shall be former, underground,
Thrown topsy-turvy, twisted, crisped, and curled,
Baked, fried or burnt, turned inside-out, or drowned,
Like all the worlds before, which have been hurled
First out of, and then back again to Chaos,
The Superstratum which will overlay us.

[Rochelle Esposito] said that she didn’t normally interfere, but wanted to tell me that it was really risky to switch organisms before getting tenure.

[Advice to would-be trippers, simply:] Go to the meadows, go to the garden, go to the woods. Open your eyes!

Dogbert (advice to Boss): Every credible scientist on earth says your products harm the environment. I recommend paying weasels to write articles casting doubt on the data. Then eat the wrong kind of foods and hope you die before the earth does.

Every teacher certainly should know something of non-euclidean geometry. Thus, it forms one of the few parts of mathematics which, at least in scattered catch-words, is talked about in wide circles, so that any teacher may be asked about it at any moment. … Imagine a teacher of physics who is unable to say anything about Röntgen rays, or about radium. A teacher of mathematics who could give no answer to questions about non-euclidean geometry would not make a better impression.
On the other hand, I should like to advise emphatically against bringing non-euclidean into regular school instruction (i.e., beyond occasional suggestions, upon inquiry by interested pupils), as enthusiasts are always recommending. Let us be satisfied if the preceding advice is followed and if the pupils learn to really understand euclidean geometry. After all, it is in order for the teacher to know a little more than the average pupil.

I cannot give any scientist of any age better advice than this: the intensity of the conviction that a hypothesis is true has no bearing on whether it is true or not. The importance of the strength of our conviction is only to provide a proportionally strong incentive to find out if the hypothesis will stand up to critical examination.

A favourite piece of advice [by William Gull] to his students was, “never disregard what a mother says;” he knew the mother’s instinct, and her perception, quickened by love, would make her a keen observer.

A good scare is worth more to a man than advice.

A physician advised his patient that had sore eyes, that he should abstain from wine; but the patient said, “I think rather, sir, from wine and water; for I have often marked it in blue eyes, and I have seen water come forth, but never wine.”

All that comes above that surface [of the globe] lies within the province of Geography. All that comes below that surface lies inside the realm of Geology. The surface of the earth is that which, so to speak, divides them and at the same time “binds them together in indissoluble union.” We may, perhaps, put the case metaphorically. The relationships of the two are rather like that of man and wife. Geography, like a prudent woman, has followed the sage advice of Shakespeare and taken unto her “an elder than herself;” but she does not trespass on the domain of her consort, nor could she possibly maintain the respect of her children were she to flaunt before the world the assertion that she is “a woman with a past.”

An old medical friend gave me some excellent practical advice. He said: “You will have for some time to go much oftener down steps than up steps. Never mind! win the good opinions of washerwomen and such like, and in time you will hear of their recommendations of you to the wealthier families by whom they are employed.” I did so, and found it succeed as predicted.
[On beginning a medical practice.]

Ask advice of him who governs himself well.

By research in pure science I mean research made without any idea of application to industrial matters but solely with the view of extending our knowledge of the Laws of Nature. I will give just one example of the ‘utility’ of this kind of research, one that has been brought into great prominence by the War—I mean the use of X-rays in surgery. Now, not to speak of what is beyond money value, the saving of pain, or, it may be, the life of the wounded, and of bitter grief to those who loved them, the benefit which the state has derived from the restoration of so many to life and limb, able to render services which would otherwise have been lost, is almost incalculable. Now, how was this method discovered? It was not the result of a research in applied science starting to find an improved method of locating bullet wounds. This might have led to improved probes, but we cannot imagine it leading to the discovery of X-rays. No, this method is due to an investigation in pure science, made with the object of discovering what is the nature of Electricity. The experiments which led to this discovery seemed to be as remote from ‘humanistic interest’ —to use a much misappropriated word—as anything that could well be imagined. The apparatus consisted of glass vessels from which the last drops of air had been sucked, and which emitted a weird greenish light when stimulated by formidable looking instruments called induction coils. Near by, perhaps, were great coils of wire and iron built up into electro-magnets. I know well the impression it made on the average spectator, for I have been occupied in experiments of this kind nearly all my life, notwithstanding the advice, given in perfect good faith, by non-scientific visitors to the laboratory, to put that aside and spend my time on something useful.

Dad [Walter C. Alvarez] … advised me to sit every few months in my reading chair for an entire evening, close my eyes and try to think of new problems to solve. I took his advice very seriously and have been glad ever since that he did.

Enlist a great mathematician and a distinguished Grecian; your problem will be solved. Such men can teach in a dwelling-house as well as in a palace. Part of the apparatus they will bring; part we will furnish.

Every mathematical book that is worth reading must be read “backwards and forwards”, if I may use the expression. I would modify Lagrange’s advice a little and say, “Go on, but often return to strengthen your faith.” When you come on a hard or dreary passage, pass it over; and come back to it after you have seen its importance or found the need for it further on.

For nearly twelve years I travelled and lived mostly among uncivilised or completely savage races, and I became convinced that they all possessed good qualities, some of them in a very remarkable degree, and that in all the great characteristics of humanity they are wonderfully like ourselves. Some, indeed, among the brown Polynesians especially, are declared by numerous independent and unprejudiced observers, to be physically, mentally, and intellectually our equals, if not our superiors; and it has always seemed to me one of the disgraces of our civilisation that these fine people have not in a single case been protected from contamination by the vices and follies of our more degraded classes, and allowed to develope their own social and political organislll under the advice of some of our best and wisest men and the protection of our world-wide power. That would have been indeed a worthy trophy of our civilisation. What we have actually done, and left undone, resulting in the degradation and lingering extermination of so fine a people, is one of the most pathetic of its tragedies.

Gentlemen, there is such a chaos in our therapeutics that we ought to be thankful for any good advice, whether it comes from an old woman, a shepherd, a blacksmith, or even a Homeopath.

Had I been present at the Creation, I would have given some useful hints for the better ordering of the universe.
Remarking on the complexity of Ptolemaic model of the universe after it was explained to him.
Footnote: Carlyle says, in his History of Frederick the Great, book ii. chap. vii. that this saying of Alphonso about Ptolemy's astronomy, 'that it seemed a crank machine; that it was pity the Creator had not taken advice,' is still remembered by mankind, — this and no other of his many sayings.

Here’s good advice for practice: go into partnership with nature; she does more than half the work and asks none of the fee.

I have been trying to point out that in our lives chance may have an astonishing influence and, if I may offer advice to the young laboratory worker, it would be this—never neglect an extraordinary appearance or happening. It may be—usually is, in fact—a false alarm that leads to nothing, but may on the other hand be the clue provided by fate to lead you to some important advance.

I have taken your advice, and the names used are anode cathode anions cations and ions; the last I shall have but little occasion for. I had some hot objections made to them here and found myself very much in the condition of the man with his son and ass who tried to please every body; but when I held up the shield of your authority, it was wonderful to observe how the tone of objection melted away.

I tell [medical students] that they are the luckiest persons on earth to be in medical school, and to forget all this worry about H.M.O.’s and keep your eye on helping the patient. It’s the best time ever to be a doctor because you can heal and treat conditions that were untreatable even a couple of years ago.

If any student comes to me and says he wants to be useful to mankind and go into research to alleviate human suffering, I advise him to go into charity instead. Research wants real egotists who seek their own pleasure and satisfaction, but find it in solving the puzzles of nature.

If I would follow your advice and Jesus could perceive it, he, as a Jewish teacher, surely would not approve of such behavior.

If we are ever in doubt what to do, it is a good rule to ask ourselves what we shall wish on the morrow that we had done.

If we follow the advice of these people [who oppose nuclear power, increased strip-mining and stepped-up off-shore oil exploration], we might as well go back into the cave right away. There would be incredible unemployment. Food production would be cut severely. In that direction lies catastrophe.

If you are young, then I say: Learn something about statistics as soon as you can. Don’t dismiss it through ignorance or because it calls for thought. … If you are older and already crowned with the laurels of success, see to it that those under your wing who look to you for advice are encouraged to look into this subject. In this way you will show that your arteries are not yet hardened, and you will be able to reap the benefits without doing overmuch work yourself. Whoever you are, if your work calls for the interpretation of data, you may be able to do without statistics, but you won’t do as well.

If you want to become a chemist, you will have to ruin your health. If you don’t ruin your health studying, you won’t accomplish anything these days in chemistry.

If you want to find out anything from the theoretical physicists about the methods they use, I advise you to stick closely to one principle: don't listen to their words, fix your attention on their deeds. To him who is a discoverer in this field the products of his imagination appear so necessary and natural that he regards them, and would like to have them regarded by others, not as creations of thought but as given realities.

If you wish to learn from the theoretical physicist anything about the methods which he uses, I would give you the following piece of advice: Don’t listen to his words, examine his achievements. For to the discoverer in that field, the constructions of his imagination appear so necessary and so natural that he is apt to treat them not as the creations of his thoughts but as given realities.

In my own view, some advice about what should be known, about what technical education should be acquired, about the intense motivation needed to succeed, and about the carelessness and inclination toward bias that must be avoided is far more useful than all the rules and warnings of theoretical logic.

It is easy for men to give advice, but difficult for one’s self to follow; we have an example in physicians: for their patients they order a strict regime, for themselves, on going to bed, they do all that they have forbidden to others.

It pays to be obvious, especially if you have a reputation for subtlety.

Learn the leading precognita of all things—no need to turn over leaf by leaf, but grasp the trunk hard and you will shake all the branches.
Advice cherished by Samuel Johnson that that, if one is to master any subject, one must first discover its general principles.

No engineer can go upon a new work and not find something peculiar, that will demand his careful reflection, and the deliberate consideration of any advice that he may receive; and nothing so fully reveals his incapacity as a pretentious assumption of knowledge, claiming to understand everything.

On consideration and by the advice of learned men, I thought it improper to unfold the secrets of the art (alchemy) to the vulgar, as few persons are capable of using its mysteries to advantage and without detriment.

Our advice is that every man should remain in the path he has struck out for himself, and refuse to be overawed by authority, hampered by prevalent opinion, or carried away by fashion.

Owing to his lack of knowledge, the ordinary man cannot attempt to resolve conflicting theories of conflicting advice into a single organized structure. He is likely to assume the information available to him is on the order of what we might think of as a few pieces of an enormous jigsaw puzzle. If a given piece fails to fit, it is not because it is fraudulent; more likely the contradictions and inconsistencies within his information are due to his lack of understanding and to the fact that he possesses only a few pieces of the puzzle. Differing statements about the nature of things, differing medical philosophies, different diagnoses and treatments—all of these are to be collected eagerly and be made a part of the individual's collection of puzzle pieces. Ultimately, after many lifetimes, the pieces will fit together and the individual will attain clear and certain knowledge.

Richard Feynman was fond of giving the following advice on how to be a genius. You have to keep a dozen of your favorite problems constantly present in your mind, although by and large they will lay in a dormant state. Every time you hear or read a new trick or a new result, test it against each of your twelve problems to see whether it helps. Every once in a while there will be a hit, and people will say, “How did he do it? He must be a genius!”

Should a young scientist working with me come to me after two years of such work and ask me what to do next, I would advise him to get out of science. After two years of work, if a man does not know what to do next, he will never make a real scientist.

Signs and symptoms indicate the present, past and future states of the three states of the body (health, illness, neutrality). According to Galen, knowledge of the present state is of advantage only to the patient as it helps him to follow the proper course of management. Knowledge of the past state is useful only to the physician inasmuch as its disclosure by him to the patient brings him a greater respect for his professional advice. Knowledge of the future state is useful to both. It gives an opportunity to the patient to be forewarned to adopt necessary preventative measures and it enhances the reputation of the physician by correctly forecasting the future developments.

Stay in college, get the knowledge. And stay there until you’re through. If they can make penicillin out of moldy bread, they can sure make something out of you.
Advice to a young person to continue his education.

The best way to learn to swim is to dive.

The commissioners of the treasury moved the king, for the relief of his estate, to disafforest some forests of his, explaining themselves of such forests as lay out of the way, not near any of the king’s houses, nor in the course of his progress; whereof he should never have use nor pleasure. “Why,” saith the king, “do you think that Solomon had use and pleasure of all his three hundred concubines?”

The reproduction of mankind is a great marvel and mystery. Had God consulted me in the matter, I should have advised him to continue the generation of the species by fashioning them of clay.

The whole value of solitude depends upon oneself; it may be a sanctuary or a prison, a haven of repose or a place of punishment, a heaven or a hell, as we ourselves make it.

The young engineer may lay to heart the advice which Mr. Moberly Bell of the London Times gave … “If your business,” said he, “is only to sweep a crossing, remember that it is your duty to make that crossing the best swept in the world.”

Train yourselves. Don’t wait to be fed knowledge out of a book. Get out and seek it. Make explorations. Do your own research work. Train your hands and your mind. Become curious. Invent your own problems and solve them. You can see things going on all about you. Inquire into them. Seek out answers to your own questions. There are many phenomena going on in nature the explanation of which cannot be found in books. Find out why these phenomena take place. Information a boy gets by himself is enormously more valuable than that which is taught to him in school.

Visualize yourself confronted with the task of killing, one after the other, a cabbage, a fly, a fish, a lizard, a guinea pig, a cat, a dog, a monkey and a baby chimpanzee. In the unlikely case that you should experience no greater inhibitions in killing the chimpanzee than in destroying the cabbage or the fly, my advice to you is to commit suicide at your earliest possible convenience, because you are a weird monstrosity and a public danger.

Von Neumann gave me an interesting idea: that you don’t have to be responsible for the world that you’re in. So I have developed a very powerful sense of social irresponsibility as a result of Von Neumann’s advice. It’s made me a very happy man ever since.

When I began my physical studies [in Munich in 1874] and sought advice from my venerable teacher Philipp von Jolly...he portrayed to me physics as a highly developed, almost fully matured science...Possibly in one or another nook there would perhaps be a dust particle or a small bubble to be examined and classified, but the system as a whole stood there fairly secured, and theoretical physics approached visibly that degree of perfection which, for example, geometry has had already for centuries.

When the last Puritan has disappeared from the earth, the man of science will take his place as a killjoy, and we shall be given the same old advice but for different reasons.

When we ask advice, we are usually looking for an accomplice.

You too can win Nobel Prizes. Study diligently. Respect DNA. Don't smoke. Don't drink. Avoid women and politics. That's my formula.

Young people, especially young women, often ask me for advice. Here it is, valeat quantum. Do not undertake a scientific career in quest of fame or money. There are easier and better ways to reach them. Undertake it only if nothing else will satisfy you; for nothing else is probably what you will receive. Your reward will be the widening of the horizon as you climb. And if you achieve that reward you will ask no other.

Your character will be what you yourself choose to make it.