'Normal science' means research firmly based upon one or more past scientific achievements, achievements that some particular scientific community acknowledges for a time as supplying the foundation for its further practice.

πολλὰ τὰ δεινὰ κοὐδὲν ἀνθρώπου δεινότερον πέλει.
Wonders are many, and none is more wonderful than man.

(1) I have told you more than I know about osteoporosis. (2) What I have told you is subject to change without notice. (3) I hope I raised more questions than I have given answers. (4) In any case, as usual, a lot more work is necessary.
Conclusion of one of his papers.

... an analysis that puts the final link in the chain, for here we see correlations between cytological evidence and genetic results that are so strong and obvious that their validity cannot be denied. This paper has been called a landmark in experimental genetics. It is more than that—it is a cornerstone.
Describing the paper 'A Correlation of Cytological and Genetic Crossings-over in Zea mays' published by Barbara McClintock and her student Harriet Creighton in the Proceedings of the National Academy of Sciences (1931), demonstrating that the exchange of genetic information that occurs during the production of sex cells is accompanied by an exchange of chromosomal material.

... I should think that anyone who considered it more reasonable for the whole universe to move in order to let the Earth remain fixed would be more irrational than one who should climb to the top of your cupola just to get a view of the city and its environs, and then demand that the whole countryside should revolve around him so that he would not have to take the trouble to turn his head.

... in going over the history of all the inventions for which history could be obtained it became more and more clear that in addition to training and in addition to extensive knowledge, a natural quality of mind was also necessary.

... in real life mistakes are likely to be irrevocable. Computer simulation, however, makes it economically practical to make mistakes on purpose. If you are astute, therefore, you can learn much more than they cost. Furthermore, if you are at all discreet, no one but you need ever know you made a mistake.

... in time of war, soldiers, however sensible, care a great deal more on some occasions about slaking their thirst than about the danger of enteric fever.
[Better known as typhoid, the disease is often spread by drinking contaminated water.]

... one of the main functions of an analogy or model is to suggest extensions of the theory by considering extensions of the analogy, since more is known about the analogy than is known about the subject matter of the theory itself … A collection of observable concepts in a purely formal hypothesis suggesting no analogy with anything would consequently not suggest either any directions for its own development.

...an idea is no more an even relatively constant thing than is a feeling or emotion or volitional process. There exist only changing and transient ideational processes; there are no permanent ideas that return again and disappear again.

...for our wisdom is better than the strength of men or of horses. ... nor is it right to prefer strength to excellent wisdom. For if there should be in the city [any athlete whose skill] is honoured more than strength ... the city would not on that account be any better governed.

...for the animals, which we resemble and which would be our equals if we did not have reason, do not reflect upon the actions or the passions of their external or internal senses, and do not know what is color, odor or sound, or if there is any differences between these objects, to which they are moved rather than moving themselves there. This comes about by the force of the impression that the different objects make on their organs and on their senses, for they cannot discern if it is more appropriate to go and drink or eat or do something else, and they do not eat or drink or do anything else except when the presence of objects or the animal imagination [l'imagination brutalle], necessitates them and transports them to their objects, without their knowing what they do, whether good or bad; which would happen to us just as to them if we were destitute of reason, for they have no enlightenment except what they must have to take their nourishment and to serve us for the uses to which God has destined them.
[Arguing the uniqueness of man by regarding animals to be merely automatons.].

...it would be a simple way of solving the goiter problem. And in addition to that it would be the biggest thing in a medical proposition to be carried out in the state of Michigan, and Michigan is a large place. And as I thought of the thing the more convinced I became that this oughtn't to be a personal thing, This ought to be something done by the Michigan State Medical Society as a body.
Recommending the addition of a trace of iodine to table salt.

...neither is it possible to discover the more remote and deeper parts of any science, if you stand but upon the level of the same science, and ascend not to a higher science.

...the remark attributed to Mrs. [Agatha] Christie that 'the older you get, the more interesting you become to an archaeologist,' was the creation of some pundit whose neck Mrs. Christie would be glad to wring if he would care to identify himself—she neither made the remark nor does she consider it particularly complimentary or amusing.

...those experiments be not only esteemed which have an immediate and present use, but those principally which are of most universal consequence for invention of other experiments, and those which give more light to the invention of causes; for the invention of the mariner's needle, which giveth the direction, is of no less benefit for navigation than the invention of the sails, which give the motion.

...travel is more than the seeing of sights; it is a change that goes on, deep and permanent, in the ideas of living.

...[T]he natural history of the rat is tragically similar to that of man ... some of the more obvious qualities in which rats resemble men — ferocity, omnivorousness, and adaptability to all climates ... the irresponsible fecundity with which both species breed at all seasons of the year with a heedlessness of consequences, which subjects them to wholesale disaster on the inevitable, occasional failure of the food supply.... [G]radually, these two have spread across the earth, keeping pace with each other and unable to destroy each other, though continually hostile. They have wandered from East to West, driven by their physical needs, and — unlike any other species of living things — have made war upon their own kind. The gradual, relentless, progressive extermination of the black rat by the brown has no parallel in nature so close as that of the similar extermination of one race of man by another...

1839—The fermentation satire
THE MYSTERY OF ALCOHOLIC FERMENTATION RESOLVED
(Preliminary Report by Letter) Schwindler
I am about to develop a new theory of wine fermentation … Depending on the weight, these seeds carry fermentation to completion somewhat less than as in the beginning, which is understandable … I shall develop a new theory of wine fermentation [showing] what simple means Nature employs in creating the most amazing phenomena. I owe it to the use of an excellent microscope designed by Pistorius.
When brewer’s yeast is mixed with water the microscope reveals that the yeast dissolves into endless small balls, which are scarcely 1/800th of a line in diameter … If these small balls are placed in sugar water, it can be seen that they consist of the eggs of animals. As they expand, they burst, and from them develop small creatures that multiply with unbelievable rapidity in a most unheard of way. The form of these animals differs from all of the 600 types described up until now. They possess the shape of a Beinsdorff still (without the cooling apparatus). The head of the tube is a sort of proboscis, the inside of which is filled with fine bristles 1/2000th of a line long. Teeth and eyes are not discernible; however, a stomach, intestinal canal, anus (a rose red dot), and organs for secretion of urine are plainly discernible. From the moment they are released from the egg one can see these animals swallow the sugar from the solution and pass it to the stomach. It is digested immediately, a process recognized easily by the resultant evacuation of excrements. In a word, these infusors eat sugar, evacuate ethyl alcohol from the intestinal canal, and carbon dioxide from the urinary organs. The bladder, in the filled state, has the form of a champagne bottle; when empty, it is a small button … As soon as the animals find no more sugar present, they eat each other up, which occurs through a peculiar manipulation; everything is digested down to the eggs which pass unchanged through the intestinal canal. Finally, one again fermentable yeast, namely the seed of the animals, which remain over.

Ath. There still remain three studies suitable for freemen. Calculation in arithmetic is one of them; the measurement of length, surface, and depth is the second; and the third has to do with the revolutions of the stars in reference to one another … there is in them something that is necessary and cannot be set aside, … if I am not mistaken, [something of] divine necessity; for as to the human necessities of which men often speak when they talk in this manner, nothing can be more ridiculous than such an application of the words.
Cle. And what necessities of knowledge are there, Stranger, which are divine and not human?
Ath. I conceive them to be those of which he who has no use nor any knowledge at all cannot be a god, or demi-god, or hero to mankind, or able to take any serious thought or charge of them.

Bernard: Oh, you’re going to zap me with penicillin and pesticides. Spare me that and I’ll spare you the bomb and aerosols. But don’t confuse progress with perfectibility. A great poet is always timely. A great philosopher is an urgent need. There’s no rush for Isaac Newton. We were quite happy with Aristotle’s cosmos. Personally, I preferred it. Fifty-five crystal spheres geared to God’s crankshaft is my idea of a satisfying universe. I can’t think of anything more trivial than the speed of light. Quarks, quasars—big bangs, black holes—who [cares]? How did you people con us out of all that status? All that money? And why are you so pleased with yourselves?
Chloe: Are you against penicillin, Bernard?
Bernard: Don’t feed the animals.

Between the frontiers of the three super-states Eurasia, Oceania, and Eastasia, and not permanently in possession of any of them, there lies a rough quadrilateral with its corners at Tangier, Brazzaville, Darwin, and Hongkong. These territories contain a bottomless reserve of cheap labour. Whichever power controls equatorial Africa, or the Middle East or Southern India or the Indonesian Archipelago, disposes also of the bodies of hundreds of millions of ill-paid and hardworking coolies, expended by their conquerors like so much coal or oil in the race to turn out more armaments, to capture more territory, to control more labour, to turn out more armaments, to capture more territory, to control…
Thus George Orwell—in his only reference to the less-developed world.
I wish I could disagree with him. Orwell may have erred in not anticipating the withering of direct colonial controls within the “quadrilateral” he speaks about; he may not quite have gauged the vehemence of urges to political self-assertion. Nor, dare I hope, was he right in the sombre picture of conscious and heartless exploitation he has painted. But he did not err in predicting persisting poverty and hunger and overcrowding in 1984 among the less privileged nations.
I would like to live to regret my words but twenty years from now, I am positive, the less-developed world will be as hungry, as relatively undeveloped, and as desperately poor, as today.

Ce grand ouvrage, toujours plus merveilleux à mesure qu’il est plus connu, nous donne une si grande idée de son ouvrier, que nous en sentons notre esprit accablé d’admiration et de respect.
[The Universe] This great work, always more amazing in proportion as it is better known, raises in us so grand an idea of its Maker, that we find our mind overwhelmed with feelings of wonder and adoration.

Ces détails scientifiques qui effarouchent les fabricans d’un certain âge, ne seront qu’un jeu pour leurs enfans, quand ils auront apprit dans leurs collèges un peu plus de mathématiques et un peu moins de Latin; un peu plus de Chimie, et un peu moins de Grec!
The scientific details which now terrify the adult manufacturer will be mere trifles to his children when they shall be taught at school, a little more Mathematics and a little less Latin, a little more Chemistry, and a little less Greek.

Chaos umpire sits
And by decision more embroils the fray
By which he reigns: next him high arbiter
Chance governs all.

Die Wissenschaft ist ein Land, welches die Eigenschaft hat, um so mehr Menschen beherbergen zu können, je mehr Bewohner sich darin sammeln; sie ist ein Schatz, der um so grösser wird, je mehr man ihn teilt. Darum kann jeder von uns in seiner Art seine Arbeit tun, und die Gemeinsamkeit bedeutet nicht Gleichförmigkeit.
Science is one land, having the ability to accommodate even more people, as more residents gather in it; it is a treasure that is the greater the more it is shared. Because of that, each of us can do his work in his own way, and the common ground does not mean conformity.

Dilbert: And we know mass creates gravity because more dense planets have more gravity.
Dogbert: How do we know which planets are more dense?
Dilbert:They have more gravity.
Dogbert: That's circular reasoning.
Dilbert: I prefer to think of it as having no loose ends.

Dilbert: It took weeks but I’ve calculated a new theory about the origin of the universe. According to my calculations it didn’t start with a “Big Bang” at all—it was more of “Phhbwt” sound. You may be wondering about the practical applications of the “Little Phhbwt” theory.
Dogbert: I was wondering when you’ll go away.

Error of confounding cause and effect.—There is no more dangerous error than confounding consequence with cause: I call it the intrinsic depravity of reason. … I take an example: everybody knows the book of the celebrated Comaro, in which he recommends his spare diet as a recipe for a long and happy life,—for a virtuous life also. Few books have been read so much… I believe hardly any book … has caused so much harm, has shortened so many lives, as this well-meant curiosity. The source of this mischief is in confounding consequence with cause. The candid Italian saw in his diet the cause of his long life, while the prerequisite to long life, the extraordinary slowness of the metabolic process, small consumption, was the cause of his spare diet. He was not at liberty to eat little or much; his frugality—was not of “free will;” he became sick when he ate more.

Every teacher certainly should know something of non-euclidean geometry. Thus, it forms one of the few parts of mathematics which, at least in scattered catch-words, is talked about in wide circles, so that any teacher may be asked about it at any moment. … Imagine a teacher of physics who is unable to say anything about Röntgen rays, or about radium. A teacher of mathematics who could give no answer to questions about non-euclidean geometry would not make a better impression.
On the other hand, I should like to advise emphatically against bringing non-euclidean into regular school instruction (i.e., beyond occasional suggestions, upon inquiry by interested pupils), as enthusiasts are always recommending. Let us be satisfied if the preceding advice is followed and if the pupils learn to really understand euclidean geometry. After all, it is in order for the teacher to know a little more than the average pupil.

Frustra fit per plura, quod fieri potest per pauciora.
It is vain to do with more what can be done with less.

Hominem ad deos nulla re propius accedunt quam salutem hominibus dando,
In nothing do men more nearly approach the gods, than in giving health to men.

If the Indians hadn’t spent the $24. In 1626 Peter Minuit, first governor of New Netherland, purchased Manhattan Island from the Indians for about $24. … Assume for simplicity a uniform rate of 7% from 1626 to the present, and suppose that the Indians had put their $24 at [compound] interest at that rate …. What would be the amount now, after 280 years? 24 x (1.07)280 = more than 4,042,000,000.
The latest tax assessment available at the time of writing gives the realty for the borough of Manhattan as $3,820,754,181. This is estimated to be 78% of the actual value, making the actual value a little more than $4,898,400,000.
The amount of the Indians’ money would therefore be more than the present assessed valuation but less than the actual valuation.

Il ne peut y avoir de langage plus universel et plus simple, plus exempt d’erreurs et d’obscurités, c'est-à-dire plus digne d'exprimer les rapports invariables des êtres naturels.
There cannot be a language more universal and more simple, more free from errors and obscurities, … more worthy to express the invariable relations of all natural things. [About mathematical analysis.]

Il y aura toujours une valeur (ou plusieurs) qui dépassera toutes les autres.
There will always be one (or more) value that will exceed all others.

La nature veut que dans certains temps les hommes se succèdent les uns aux autres par le moyen de la mort; il leur est permis de se défendre contr’elle jusqu’à un certain point; mais passé cela, on aura beau faire de nouvelles découvertes dans l’Anatomie, on aura beau pénétrer de plus en plus dans les secrets de la structure du corps humain, on ne prendra point la Nature pour dupe, on mourra comme à l’ordinaire.
Nature intends that at fixed periods men should succeed each other by the instrumentality of death. They are allowed to keep it at bay up to a certain point; but when that is passed, it will be of no use to make new discoveries in anatomy, or to penetrate more and more into the secrets of the structure of the human body; we shall never outwit nature, we shall die as usual.

La vérité ne diffère de l'erreur qu'en deux points: elle est un peu plus difficile à prouver et beaucoup plus difficile à faire admettre. (Dec 1880)
Truth is different from error in two respects: it is a little harder to prove and more difficult to admit.

Le savant n’étudie pas la nature parce que cela est utile; il l’étudie parce qu’il y prend plaisir et il y prend plaisir parce qu’elle est belle. Si la nature n’était pas belle, elle ne vaudrait pas la peine d’être connue, la vie ne vaudrait pas la peine d’être vécue.
The scientist does not study nature because it is useful to do so. He studies it because he takes pleasure in it, and he takes pleasure in it because it is beautiful. If nature were not beautiful, it would not be worth knowing, and life would not be worth living. I am not speaking, of course, of the beauty which strikes the senses, of the beauty of qualities and appearances. I am far from despising this, but it has nothing to do with science. What I mean is that more intimate beauty which comes from the harmonious order of its parts, and which a pure intelligence can grasp.

L’analyse mathématique … dans l’étude de tous les phénomènes; elle les interprète par le même langage, comme pour attester l’unité et la simplicité du plan de l’univers, et rendre encore plus manifeste cet ordre immuable qui préside à toutes les causes naturelles.
Mathematical analysis … in the study of all phenomena, interprets them by the same language, as if to attest the unity and simplicity of the plan of the universe, and to make still more evident that unchangeable order which presides over all natural causes.

Medicus enim nihil aliud est quam animi consolatio
A doctor is nothing more than consolation for the spirit.

On se persuade mieux, pour l’ordinaire, par les raisons qu’on a soi-même trouvées, que par celles qui sont venues dans l’esprit des autres.
We are generally more effectually persuaded by reasons we have ourselves discovered than by those which have occurred to others.

Prospero: Hast thou, spirit,
Performed, to point, the tempest that I bade thee?
Ariel: To every article.
I boarded the king’s ship. Now on the beak,
Now in the waist, the deck, in every cabin,
I flamed amazement.
Sometime I’d divide
And burn in many places; on the topmast,
The yards, and bowsprit would I flame distinctly,
Then meet and join. Jove’s lightnings, the precursors
O’ th’ dreadful thunderclaps, more momentary
And sight-outrunning were not. The fire and cracks
Of sulphurous roaring the most mighty Neptune
Seem to besiege, and make his bold waves tremble;
Yea, his dread trident shake.

Qu'une goutee de vin tombe dans un verre d'eau; quelle que soit la loi du movement interne du liquide, nous verrons bientôt se colorer d'une teinte rose uniforme et à partir de ce moment on aura beau agiter le vase, le vin et l'eau ne partaîtront plus pouvoir se séparer. Tout cela, Maxwell et Boltzmann l'ont expliqué, mais celui qui l'a vu plus nettement, dans un livre trop peu lu parce qu'il est difficile à lire, c'est Gibbs dans ses principes de la Mécanique Statistique.
Let a drop of wine fall into a glass of water; whatever be the law that governs the internal movement of the liquid, we will soon see it tint itself uniformly pink and from th at moment on, however we may agitate the vessel, it appears that the wine and water can separate no more. All this, Maxwell and Boltzmann have explained, but the one who saw it in the cleanest way, in a book that is too little read because it is difficult to read, is Gibbs, in his Principles of Statistical Mechanics.

Question: If you walk on a dry path between two walls a few feet apart, you hear a musical note or “ring” at each footstep. Whence comes this?
Answer: This is similar to phosphorescent paint. Once any sound gets between two parallel reflectors or walls, it bounds from one to the other and never stops for a long time. Hence it is persistent, and when you walk between the walls you hear the sounds made by those who walked there before you. By following a muffin man down the passage within a short time you can hear most distinctly a musical note, or, as it is more properly termed in the question, a “ring” at every (other) step.

Ratbert (as lab rat, to scientist): Doc, we have to talk. Every day you feed me over a hundred pounds of macaroni and cheese. At first I thought you were just being a good host. But lately I’ve been thinking it could be something far more sinister.
Scientist (thinking): Macaroni and cheese causes paranoia.

Se è vero che ci si abitua al dolore, come mai con l’andare degli anni si soffre sempre di píu?
If it is true that one gets used to suffering, how is it that, as the years go by, one always suffers more?

That the general characters of the big group to which the embryo belongs appear in development earlier than the special characters. In agreement with this is the fact that the vesicular form is the most general form of all; for what is common in a greater degree to all animals than the opposition of an internal and an external surface?
The less general structural relations are formed after the more general, and so on until the most special appear.
The embryo of any given form, instead of passing through the state of other definite forms, on the contrary separates itself from them.
Fundamentally the embryo of a higher animal form never resembles the adult of another animal form, but only its embryo.

That the Sun will not rise Tomorrow is no less intelligible a Proposition and implies no more contradiction than the Affirmation that it will rise. We should in vain, therefore, attempt to demonstrate its falsehood.

The Charms of Statistics.—It is difficult to understand why statisticians commonly limit their inquiries to Averages, and do not revel in more comprehensive views. Their souls seem as dull to the charm of variety as that of the native of one of our flat English counties, whose retrospect of Switzerland was that, if its mountains could be thrown into its lakes, two nuisances would be got rid of at once. An Average is but a solitary fact, whereas if a single other fact be added to it, an entire Normal Scheme, which nearly corresponds to the observed one, starts potentially into existence. Some people hate the very name of statistics, but I find them full of beauty and interest. Whenever they are not brutalised, but delicately handled by the higher methods, and are warily interpreted, their power of dealing with complicated phenomena is extraordinary. They are the only tools by which an opening can be cut through the formidable thicket of difficulties that bars the path of those who pursue the Science of man.

Ut ager quamvis fertilis sine cultura fructuosus esse non potest, sic sine doctrina animus.
A mind without instruction can no more bear fruit than can a field, however fertile, without cultivation.

[About gorillas] You take these fine, regal animals. How many (human) fathers have the same sense of paternity? How many human mothers are more caring? The family structure is unbelievably strong.

[Almost certainly not by Einstein.] The more I study science, the more I believe in God.

[Describing the effects of over-indulgence in wine:]
But most too passive, when the blood runs low
Too weakly indolent to strive with pain,
And bravely by resisting conquer fate,
Try Circe's arts; and in the tempting bowl
Of poisoned nectar sweet oblivion swill.
Struck by the powerful charm, the gloom dissolves
In empty air; Elysium opens round,
A pleasing frenzy buoys the lightened soul,
And sanguine hopes dispel your fleeting care;
And what was difficult, and what was dire,
Yields to your prowess and superior stars:
The happiest you of all that e'er were mad,
Or are, or shall be, could this folly last.
But soon your heaven is gone: a heavier gloom
Shuts o'er your head; and, as the thundering stream,
Swollen o'er its banks with sudden mountain rain,
Sinks from its tumult to a silent brook,
So, when the frantic raptures in your breast
Subside, you languish into mortal man;
You sleep, and waking find yourself undone,
For, prodigal of life, in one rash night
You lavished more than might support three days.
A heavy morning comes; your cares return
With tenfold rage. An anxious stomach well
May be endured; so may the throbbing head;
But such a dim delirium, such a dream,
Involves you; such a dastardly despair
Unmans your soul, as maddening Pentheus felt,
When, baited round Citheron's cruel sides,
He saw two suns, and double Thebes ascend.

[Instead of collecting stamps, he collected dictionaries and encyclopaedias:] Because you can learn more from them.

[Pechblende] einer eigenthümlichen, selbstständigen metallischen Substanz bestehe. Es fallen folglich auch deren bisherige Benennungen, als: Ресhblende Eisenpecherz, hinweg, welche nun durch einen neuen ausschliessend bezeichnenden Namen zu ersetzen sind. Ich habe dazu den Namen: Uranerz (Uranium) erwählt; zu einigem Andenken, dass die chemische Ausfindung dieses neuen Metallkörpers in die Epoche der astronomischen. Entdeckung des Planeten Uranus gefallen sei.
[Pitchblende] consists of a peculiar, distinct, metallic substance. Therefore its former denominations, pitch-blende, pitch-iron-ore, &c. are no longer applicable, and must be supplied by another more appropriate name.—I have chosen that of uranite, (Uranium), as a kind of memorial, that the chemical discovery of this new metal happened in the period of the astronomical discovery of the new planet Uranus.

[Question: Do you feel that scientists correct themselves as often as they should?]
More often than politicians, but not as often as they should.

[When asked “Dr. Einstein, why is it that when the mind of man has stretched so far as to discover the structure of the atom we have been unable to devise the political means to keep the atom from destroying us?”] That is simple, my friend. It is because politics is more difficult than physics.

SCIENCE: a way of finding things out and then making them work. Science explains what is happening around us the whole time. So does RELIGION, but science is better because it comes up with more understandable excuses when it’s wrong.

A basis of physical science no more justifies dogmatism than a metaphysical basis does.

A biologist, if he wishes to know how many toes a cat has, does not "frame the hypothesis that the number of feline digital extremities is 4, or 5, or 6," he simply looks at a cat and counts. A social scientist prefers the more long-winded expression every time, because it gives an entirely spurious impression of scientificness to what he is doing.

A box is more a coffin for the human spirit than an inspiration.

A chemical name should not be a phrase, it ought not to require circumlocutions to become definite; it should not be of the type “Glauber’s salt”, which conveys nothing about the composition of the substance; it should recall the constituents of a compound; it should be non-committal if nothing is known about the substance; the names should preferably be coined from Latin or Greek, so that their meaning can be more widely and easily understood; the form of the words should be such that they fit easily into the language into which they are to be incorporated.

A circumstance which influenced my whole career more than any other … was my friendship with Professor Henslow … a man who knew every branch of science…. During the latter half of my time at Cambridge [I] took long walks with him on most days; so that I was called by some of the dons “the man who walks with Henslow.”

A closer look at the course followed by developing theory reveals for a start that it is by no means as continuous as one might expect, but full of breaks and at least apparently not along the shortest logical path. Certain methods often afforded the most handsome results only the other day, and many might well have thought that the development of science to infinity would consist in no more than their constant application. Instead, on the contrary, they suddenly reveal themselves as exhausted and the attempt is made to find other quite disparate methods. In that event there may develop a struggle between the followers of the old methods and those of the newer ones. The former's point of view will be termed by their opponents as out-dated and outworn, while its holders in turn belittle the innovators as corrupters of true classical science.

A common fallacy in much of the adverse criticism to which science is subjected today is that it claims certainty, infallibility and complete emotional objectivity. It would be more nearly true to say that it is based upon wonder, adventure and hope.

A comparatively small variety of species is found in the older rocks, although of some particular ones the remains are very abundant; ... Ascending to the next group of rocks, we find the traces of life become more abundant, the number of species extended.

A computer lets you make more mistakes faster than any invention in human history—with the possible exceptions of handguns and tequila.

A cosmic mystery of immense proportions, once seemingly on the verge of solution, has deepened and left astronomers and astrophysicists more baffled than ever. The crux ... is that the vast majority of the mass of the universe seems to be missing.
[Reporting a Nature article discrediting explanation of invisible mass being due to neutrinos]

A day of worry is more exhausting than a week of work.

A discovery in science, or a new theory, even when it appears most unitary and most all-embracing, deals with some immediate element of novelty or paradox within the framework of far vaster, unanalysed, unarticulated reserves of knowledge, experience, faith, and presupposition. Our progress is narrow; it takes a vast world unchallenged and for granted. This is one reason why, however great the novelty or scope of new discovery, we neither can, nor need, rebuild the house of the mind very rapidly. This is one reason why science, for all its revolutions, is conservative. This is why we will have to accept the fact that no one of us really will ever know very much. This is why we shall have to find comfort in the fact that, taken together, we know more and more.

A discovery is like falling in love and reaching the top of a mountain after a hard climb all in one, an ecstasy not induced by drugs but by the revelation of a face of nature that no one has seen before and that often turns out to be more subtle and wonderful than anyone had imagined.

A few generations ago the clergy, or to speak more accurately, large sections of the clergy were the standing examples of obscurantism. Today their place has been taken by scientists.

A few of the results of my activities as a scientist have become embedded in the very texture of the science I tried to serve—this is the immortality that every scientist hopes for. I have enjoyed the privilege, as a university teacher, of being in a position to influence the thought of many hundreds of young people and in them and in their lives I shall continue to live vicariously for a while. All the things I care for will continue for they will be served by those who come after me. I find great pleasure in the thought that those who stand on my shoulders will see much farther than I did in my time. What more could any man want?

A formative influence on my undergraduate self was the response of a respected elder statesmen of the Oxford Zoology Department when an American visitor had just publicly disproved his favourite theory. The old man strode to the front of the lecture hall, shook the American warmly by the hand and declared in ringing, emotional tones: ‘My dear fellow, I wish to thank you. I have been wrong these fifteen years.’ And we clapped our hands red. Can you imagine a Government Minister being cheered in the House of Commons for a similar admission? “Resign, Resign” is a much more likely response!

A fossil hunter needs sharp eyes and a keen search image, a mental template that subconsciously evaluates everything he sees in his search for telltale clues. A kind of mental radar works even if he isn’t concentrating hard. A fossil mollusk expert has a mollusk search image. A fossil antelope expert has an antelope search image. … Yet even when one has a good internal radar, the search is incredibly more difficult than it sounds. Not only are fossils often the same color as the rocks among which they are found, so they blend in with the background; they are also usually broken into odd-shaped fragments. … In our business, we don’t expect to find a whole skull lying on the surface staring up at us. The typical find is a small piece of petrified bone. The fossil hunter’s search therefore has to have an infinite number of dimensions, matching every conceivable angle of every shape of fragment of every bone on the human body.
Describing the skill of his co-worker, Kamoya Kimeu, who discovered the Turkana Boy, the most complete specimen of Homo erectus, on a slope covered with black lava pebbles.

A game is on, at the other end of this infinite distance, and heads or tails will turn up. What will you wager? According to reason you cannot leave either; according to reason you cannot leave either undone... Yes, but wager you must; there is no option, you have embarked on it. So which will you have. Come. Since you must choose, let us see what concerns you least. You have two things to lose: truth and good, and two things to stake: your reason and your will, your knowledge and your happiness. And your nature has two things to shun: error and misery. Your reason does not suffer by your choosing one more than the other, for you must choose. That is one point cleared. But your happiness? Let us weigh gain and loss in calling heads that God is. Reckon these two chances: if you win, you win all; if you lose, you lose naught. Then do not hesitate, wager that He is.

A good farmer is nothing more nor less than a handy man with a sense of humus.

A good scare is worth more to a man than advice.

A government, at bottom, is nothing more than a gang of men, and as a practical matter most of them are inferior men ... Government is actually the worst failure of civilized man. There has never been a really good one, and even those that are most tolerable are arbitrary, cruel, grasping and unintelligent. Indeed, it would not be far wrong to describe the best as the common enemy of all decent citizens.

A great surgeon performs operations for stone by a single method; later he makes a statistical summary of deaths and recoveries, and he concludes from these statistics that the mortality law for this operation is two out of five. Well, I say that this ratio means literally nothing scientifically and gives us no certainty in performing the next operation; for we do not know whether the next case will be among the recoveries or the deaths. What really should be done, instead of gathering facts empirically, is to study them more accurately, each in its special determinism. We must study cases of death with great care and try to discover in them the cause of mortal accidents so as to master the cause and avoid the accidents.

A harmless and a buoyant cheerfulness are not infrequent concomitants of genius; and we are never more deceived than when we mistake gravity for greatness, solemnity for science, and pomposity for erudition.

A hundred years ago … an engineer, Herbert Spencer, was willing to expound every aspect of life, with an effect on his admiring readers which has not worn off today.
Things do not happen quite in this way nowadays. This, we are told, is an age of specialists. The pursuit of knowledge has become a profession. The time when a man could master several sciences is past. He must now, they say, put all his efforts into one subject. And presumably, he must get all his ideas from this one subject. The world, to be sure, needs men who will follow such a rule with enthusiasm. It needs the greatest numbers of the ablest technicians. But apart from them it also needs men who will converse and think and even work in more than one science and know how to combine or connect them. Such men, I believe, are still to be found today. They are still as glad to exchange ideas as they have been in the past. But we cannot say that our way of life is well-fitted to help them. Why is this?

A learned man is an idler who kills time with study. Beware of his false knowledge: it is more dangerous than ignorance.

A lecture is much more of a dialogue than many of you probably realize.

A life spent in making mistakes is not only more honorable but more useful than a life spent doing nothing.

A living speck—the merest dab of life—capable of pleasure and pain, is far more interesting to me than all the immensities of mere matter.

A lot of scientific papers do deal with matters of atheoretical fact ... for example, whenever somebody finds a new “world's largest dinosaur,” which has only slightly more scientific relevance than shooting the record moose. In short, not everything that gets published in scientific journals bears the distinctive hallmarks of science.

A machine has value only as it produces more than it consumes—so check your value to the community.

A map of the moon... should be in every geological lecture room; for no where can we have a more complete or more magnificent illustration of volcanic operations. Our sublimest volcanoes would rank among the smaller lunar eminences; and our Etnas are but spitting furnaces.

A mathematician thinks that two points are enough to define a straight line, while a physicist wants more data.

A mathematician, like a painter or a poet, is a maker of patterns. If his patterns are more permanent than theirs, it is because they are made with ideas.

A mathematician’s work is mostly a tangle of guesswork, analogy, wishful thinking and frustration, and proof, far from being the core of discovery, is more often than not a way of making sure that our minds are not playing tricks.

A mile and a half from town, I came to a grove of tall cocoanut trees, with clean, branchless stems reaching straight up sixty or seventy feet and topped with a spray of green foliage sheltering clusters of cocoanuts—not more picturesque than a forest of colossal ragged parasols, with bunches of magnified grapes under them, would be. I once heard a grouty northern invalid say that a cocoanut tree might be poetical, possibly it was; but it looked like a feather-duster struck by lightning. I think that describes it better than a picture—and yet, without any question, there is something fascinating about a cocoanut tree—and graceful, too.

A Miracle is a Violation of the Laws of Nature; and as a firm and unalterable Experience has established these Laws, the Proof against a Miracle, from the very Nature of the Fact, is as entire as any Argument from Experience can possibly be imagined. Why is it more than probable, that all Men must die; that Lead cannot, of itself, remain suspended in the Air; that Fire consumes Wood, and is extinguished by Water; unless it be, that these Events are found agreeable to the Laws of Nature, and there is required a Violation of these Laws, or in other Words, a Miracle to prevent them? Nothing is esteem'd a Miracle, if it ever happen in the common Course of Nature... There must, therefore, be a uniform Experience against every miraculous Event, otherwise the Event would not merit that Appellation. And as a uniform Experience amounts to a Proof, there is here a direct and full Proof, from the Nature of the Fact, against the Existence of any Miracle; nor can such a Proof be destroy'd, or the Miracle render'd credible, but by an opposite Proof, which is superior.

A modern branch of mathematics, having achieved the art of dealing with the infinitely small, can now yield solutions in other more complex problems of motion, which used to appear insoluble. This modern branch of mathematics, unknown to the ancients, when dealing with problems of motion, admits the conception of the infinitely small, and so conforms to the chief condition of motion (absolute continuity) and thereby corrects the inevitable error which the human mind cannot avoid when dealing with separate elements of motion instead of examining continuous motion. In seeking the laws of historical movement just the same thing happens. The movement of humanity, arising as it does from innumerable human wills, is continuous. To understand the laws of this continuous movement is the aim of history. … Only by taking an infinitesimally small unit for observation (the differential of history, that is, the individual tendencies of man) and attaining to the art of integrating them (that is, finding the sum of these infinitesimals) can we hope to arrive at the laws of history.

A newspaper is a device for making the ignorant more ignorant and the crazy crazier.

A noteworthy and often-remarked similarity exists between the facts and methods of geology and those of linguistic study. The science of language is, as it were, the geology of the most modern period, the Age of the Man, having for its task to construct the history of development of the earth and its inhabitants from the time when the proper geological record remains silent … The remains of ancient speech are like strata deposited in bygone ages, telling of the forms of life then existing, and of the circumstances which determined or affected them; while words are as rolled pebbles, relics of yet more ancient formations, or as fossils, whose grade indicates the progress of organic life, and whose resemblances and relations show the correspondence or sequence of the different strata; while, everywhere, extensive denudation has marred the completeness of the record, and rendered impossible a detailed exhibition of the whole course of development.

A number of years ago, when I was a freshly-appointed instructor, I met, for the first time, a certain eminent historian of science. At the time I could only regard him with tolerant condescension.
I was sorry of the man who, it seemed to me, was forced to hover about the edges of science. He was compelled to shiver endlessly in the outskirts, getting only feeble warmth from the distant sun of science- in-progress; while I, just beginning my research, was bathed in the heady liquid heat up at the very center of the glow.
In a lifetime of being wrong at many a point, I was never more wrong. It was I, not he, who was wandering in the periphery. It was he, not I, who lived in the blaze.
I had fallen victim to the fallacy of the “growing edge;” the belief that only the very frontier of scientific advance counted; that everything that had been left behind by that advance was faded and dead.
But is that true? Because a tree in spring buds and comes greenly into leaf, are those leaves therefore the tree? If the newborn twigs and their leaves were all that existed, they would form a vague halo of green suspended in mid-air, but surely that is not the tree. The leaves, by themselves, are no more than trivial fluttering decoration. It is the trunk and limbs that give the tree its grandeur and the leaves themselves their meaning.
There is not a discovery in science, however revolutionary, however sparkling with insight, that does not arise out of what went before. “If I have seen further than other men,” said Isaac Newton, “it is because I have stood on the shoulders of giants.”

A painter makes patterns with shapes and colours, a poet with words. A painting may embody an “idea,” but the idea is usually commonplace and unimportant. In poetry, ideas count for a good deal more; but, as Housman insisted, the importance of ideas in poetry is habitually exaggerated. … The poverty of ideas seems hardly to affect the beauty of the verbal pattern. A mathematician, on the other hand, has no material to work with but ideas, and so his patterns are likely to last longer, since ideas wear less with time than words.

A physician is obligated to consider more than a diseased organ, more than even the whole man—he must view the man in his world.

A physicist learns more and more about less and less, until he knows everything about nothing; whereas a philosopher learns less and less about more and more, until he knows nothing about everything.

A poet is, after all, a sort of scientist, but engaged in a qualitative science in which nothing is measurable. He lives with data that cannot be numbered, and his experiments can be done only once. The information in a poem is, by definition, not reproducible. ... He becomes an equivalent of scientist, in the act of examining and sorting the things popping in [to his head], finding the marks of remote similarity, points of distant relationship, tiny irregularities that indicate that this one is really the same as that one over there only more important. Gauging the fit, he can meticulously place pieces of the universe together, in geometric configurations that are as beautiful and balanced as crystals.

A powerful telescope superior to and more powerful than any telescope ever yet made … and also, a suitable Observatory connected therewith … and shall be made useful in promoting science.

A reference to the two sorts of doctors is also found in the Republic: “Now you know that when patients do not require medicine, but have only to be put under a regimen, the inferior sort of practitioner is deemed to be good enough; but when medicine has to be given, then the doctor should be more of a man.”

A research laboratory jealous of its reputation has to develop less formal, more intimate ways of forming a corporate judgment of the work its people do. The best laboratories in university departments are well known for their searching, mutual questioning.

A science is said to be useful if its development tends to accentuate the existing inequalities in the distribution of wealth, or more directly promotes the destruction of human life.

A scientific writer can scarcely encounter anything more undesirable than, after completing a work, to have one of the foundations shaken. I became aware of this situation through a letter from Mr. Bertrand Russell as the printing of this volume neared completion.

A scientist has to be neutral in his search for the truth, but he cannot be neutral as to the use of that truth when found. If you know more than other people, you have more responsibility, rather than less.

A scientist who would know the laws of nature must sit passively before nature. He may not dictate to nature its laws, nor may he impose his own intelligence upon nature; rather, the more passive he is before nature, the more nature will reveal its secrets.

A sign of a celebrity is often that his name is worth more than his services.

A small bubble of air remained unabsorbed... if there is any part of the phlogisticated air [nitrogen] of our atmosphere which differs from the rest, and cannot be reduced to nitrous acid, we may safely conclude that it is not more than 1/120 part of the whole.
Cavendish did not realize the significance of the remaining small bubble. Not until a century later were the air’s Noble Gases appreciated.

A species consists of a group of populations which replace each other geographically or ecologically and of which the neighboring ones integrate or hybridise wherever they are in contact or which are potentially capable of doing so (with one or more of the populations) in those cases where contact is prevented by geographical or ecological barriers.

A study of Disease—of Pestilences methodically prepared and deliberately launched upon man and beast—is certainly being pursue in the laboratories of more than one great country. Blight to destroy crops, Anthrax to slay horses and cattle, Plague to poison not armies but whole districts—such are the lines along which military science is remorselessly advancing.

A terrible wilderness of mountainous country constitutes the immediate environment of St. Paul’s. It is a precipitous cliff into the abyss, a gate of hell, more horrible than the fantasy of Dante could express it.

A theory is the more impressive the greater the simplicity of its premises is, the more different kinds of things it relates, and the more extended is its area of applicability. Therefore the deep impression which classical thermodynamics made upon me. It is the only physical theory of universal content concerning which I am convinced that within the framework of the applicability of its basic concepts, it will never be overthrown.

A theory with mathematical beauty is more likely to be correct than an ugly one that fits some experimental data. God is a mathematician of a very high order, and He used very advanced mathematics in constructing the universe.

A tree is beautiful, but what’s more, it has a right to life; like water, the sun and the stars, it is essential. Life on earth is inconceivable without trees. Forests create climate, climate influences peoples’ character, and so on and so forth. There can be neither civilization nor happiness if forests crash down under the axe, if the climate is harsh and severe, if people are also harsh and severe. ... What a terrible future!

A vision of the whole of life!. Could any human undertaking be ... more grandiose? This attempt stands without rival as the most audacious enterprise in which the mind of man has ever engaged ... Here is man, surrounded by the vastness of a universe in which he is only a tiny and perhaps insignificant part—and he wants to understand it.

A weird happening has occurred in the case of a lansquenet named Daniel Burghammer, of the squadron of Captain Burkhard Laymann Zu Liebenau, of the honorable Madrucci Regiment in Piadena, in Italy. When the same was on the point of going to bed one night he complained to his wife, to whom he had been married by the Church seven years ago, that he had great pains in his belly and felt something stirring therein. An hour thereafter he gave birth to a child, a girl. When his wife was made aware of this, she notified the occurrence at once. Thereupon he was examined and questioned. … He confessed on the spot that he was half man and half woman and that for more than seven years he had served as a soldier in Hungary and the Netherlands… . When he was born he was christened as a boy and given in baptism the name of Daniel… . He also stated that while in the Netherlands he only slept once with a Spaniard, and he became pregnant therefrom. This, however, he kept a secret unto himself and also from his wife, with whom he had for seven years lived in wedlock, but he had never been able to get her with child… . The aforesaid soldier is able to suckle the child with his right breast only and not at all on the left side, where he is a man. He has also the natural organs of a man for passing water. Both are well, the child is beautiful, and many towns have already wished to adopt it, which, however, has not as yet been arranged. All this has been set down and described by notaries. It is considered in Italy to be a great miracle, and is to be recorded in the chronicles. The couple, however, are to be divorced by the clergy.

A well-chosen anthology is a complete dispensary of medicine for the more common mental disorders, and may be used as much for prevention as cure.

A wise physician, skill’d our wounds to heal, is more than armies to the public weal.

A work of morality, politics, criticism will be more elegant, other things being equal, if it is shaped by the hand of geometry.

A zygote is a gamete’s way of producing more gametes. This may be the purpose of the universe.

About 6 or 8 years ago My Ingenious friend Mr John Robinson having [contrived] conceived that a fire engine might be made without a Lever—by Inverting the Cylinder & placing it above the mouth of the pit proposed to me to make a model of it which was set about by having never Compleated & I [being] having at that time Ignorant little knoledge of the machine however I always thought the Machine Might be applied to [more] other as valuable purposes [than] as drawing Water.

About 85 per cent of my “thinking” time was spent getting into a position to think, to make a decision, to learn something I needed to know. Much more time went into finding or obtaining information than into digesting it. Hours went into the plotting of graphs... When the graphs were finished, the relations were obvious at once, but the plotting had to be done in order to make them so.

About medications that are drunk or applied to wounds it is worth learning from everyone; for people do not discover these by reasoning but by chance, and experts not more than laymen.

Absolute space, that is to say, the mark to which it would be necessary to refer the earth to know whether it really moves, has no objective existence…. The two propositions: “The earth turns round” and “it is more convenient to suppose the earth turns round” have the same meaning; there is nothing more in the one than in the other.

Absorbed in the special investigation, I paid no heed to the edifice which was meanwhile unconsciously building itself up. Having however completed the comparison of the fossil species in Paris, I wanted, for the sake of an easy revision of the same, to make a list according to their succession in geological formations, with a view of determining the characteristics more exactly and bringing them by their enumeration into bolder relief. What was my joy and surprise to find that the simplest enumeration of the fossil fishes according to their geological succession was also a complete statement of the natural relations of the families among themselves; that one might therefore read the genetic development of the whole class in the history of creation, the representation of the genera and species in the several families being therein determined; in one word, that the genetic succession of the fishes corresponds perfectly with their zoological classification, and with just that classification proposed by me.

Access to more information isn’t enough—the information needs to be correct, timely, and presented in a manner that enables the reader to learn from it. The current network is full of inaccurate, misleading, and biased information that often crowds out the valid information. People have not learned that “popular” or “available” information is not necessarily valid.

Accordingly the primordial state of things which I picture is an even distribution of protons and electrons, extremely diffuse and filling all (spherical) space, remaining nearly balanced for an exceedingly long time until its inherent instability prevails. We shall see later that the density of this distribution can be calculated; it was about one proton and electron per litre. There is no hurry for anything to begin to happen. But at last small irregular tendencies accumulate, and evolution gets under way. The first stage is the formation of condensations ultimately to become the galaxies; this, as we have seen, started off an expansion, which then automatically increased in speed until it is now manifested to us in the recession of the spiral nebulae.
As the matter drew closer together in the condensations, the various evolutionary processes followed—evolution of stars, evolution of the more complex elements, evolution of planets and life.

Accordingly, we find Euler and D'Alembert devoting their talent and their patience to the establishment of the laws of rotation of the solid bodies. Lagrange has incorporated his own analysis of the problem with his general treatment of mechanics, and since his time M. Poinsôt has brought the subject under the power of a more searching analysis than that of the calculus, in which ideas take the place of symbols, and intelligent propositions supersede equations.

Accountants and second-rate business school jargon are in the ascendant. Costs, which rise rapidly, and are easily ascertained and comprehensible, now weigh more heavily in the scales than the unquantifiable and unpredictable values and future material progress. Perhaps science will only regain its lost primacy as peoples and government begin to recognize that sound scientific work is the only secure basis for the construction of policies to ensure the survival of Mankind without irreversible damage to Planet Earth.

Adam, the first man, didn’t know anything about the nucleus but Dr. George Gamow, visiting professor from George Washington University, pretends he does. He says for example that the nucleus is 0.00000000000003 feet in diameter. Nobody believes it, but that doesn't make any difference to him.
He also says that the nuclear energy contained in a pound of lithium is enough to run the United States Navy for a period of three years. But to get this energy you would have to heat a mixture of lithium and hydrogen up to 50,000,000 degrees Fahrenheit. If one has a little stove of this temperature installed at Stanford, it would burn everything alive within a radius of 10,000 miles and broil all the fish in the Pacific Ocean.
If you could go as fast as nuclear particles generally do, it wouldn’t take you more than one ten-thousandth of a second to go to Miller's where you could meet Gamow and get more details.

Advances in medicine and agriculture have saved vastly more lives than have been lost in all the wars in history.

Advocacy of leaf protein as a human food is based on the undisputed fact that forage crops (such as lucerne) give a greater yield of protein than other types of crops. Even with connventional food crops there is more protein in the leafy parts than in the seeds or tubs that are usually harvested.

After I had addressed myself to this very difficult and almost insoluble problem, the suggestion at length came to me how it could be solved with fewer and much simpler constructions than were formerly used, if some assumptions (which are called axioms) were granted me. They follow in this order.
There is no one center of all the celestial circles or spheres.
The center of the earth is not the center of the universe, but only of gravity and of the lunar sphere.
All the spheres revolve about the sun as their mid-point, and therefore the sun is the center of the universe.
The ratio of the earth's distance from the sun to the height of the firmament is so much smaller than the ratio of the earth's radius to its distance from the sun that the distance from the earth to the sun is imperceptible in comparison with the height of the firmament.
Whatever motion appears in the firmament arises not from any motion of the firmament, but from the earth's motion. The earth together with its circumjacent elements performs a complete rotation on its fixed poles in a daily motion, while the firmament and highest heaven abide unchanged.
What appears to us as motions of the sun arise not from its motion but from the motion of the earth and our sphere, with which we revolve about the sun like any other planet. The earth has, then, more than one motion.
The apparent retrograde and direct motion of the planets arises not from their motion but from the earth's. The motion of the earth alone, therefore, suffices to explain so many apparent inequalities in the heavens.