[No one will be able to] deter the scientific mind from probing into the unknown any more than Canute could command the tides.
Comment upon the U.S. Supreme Court's 1980 decision permitting the patenting of life forms.

All of our experience indicates that life can manifest itself only in a concrete form, and that it is bound to certain substantial loci. These loci are cells and cell formations. But we are far from seeking the last and highest level of understanding in the morphology of these loci of life. Anatomy does not exclude physiology, but physiology certainly presupposes anatomy. The phenomena that the physiologist investigates occur in special organs with quite characteristic anatomical arrangements; the various morphological parts disclosed by the anatomist are the bearers of properties or, if you will, of forces probed by the physiologist; when the physiologist has established a law, whether through physical or chemical investigation, the anatomist can still proudly state: This is the structure in which the law becomes manifest.

As we push ever more deeply into the universe, probing its secrets, discovering its way, we must also constantly try to learn to cooperate across the frontiers that really divide earth’s surface.

Astronomy may be revolutionized more than any other field of science by observations from above the atmosphere. Study of the planets, the Sun, the stars, and the rarified matter in space should all be profoundly influenced by measurements from balloons, rockets, probes and satellites. ... In a new adventure of discovery no one can foretell what will be found, and it is probably safe to predict that the most important new discovery that will be made with flying telescopes will be quite unexpected and unforeseen. (1961)

By research in pure science I mean research made without any idea of application to industrial matters but solely with the view of extending our knowledge of the Laws of Nature. I will give just one example of the ‘utility’ of this kind of research, one that has been brought into great prominence by the War—I mean the use of X-rays in surgery. Now, not to speak of what is beyond money value, the saving of pain, or, it may be, the life of the wounded, and of bitter grief to those who loved them, the benefit which the state has derived from the restoration of so many to life and limb, able to render services which would otherwise have been lost, is almost incalculable. Now, how was this method discovered? It was not the result of a research in applied science starting to find an improved method of locating bullet wounds. This might have led to improved probes, but we cannot imagine it leading to the discovery of X-rays. No, this method is due to an investigation in pure science, made with the object of discovering what is the nature of Electricity. The experiments which led to this discovery seemed to be as remote from ‘humanistic interest’ —to use a much misappropriated word—as anything that could well be imagined. The apparatus consisted of glass vessels from which the last drops of air had been sucked, and which emitted a weird greenish light when stimulated by formidable looking instruments called induction coils. Near by, perhaps, were great coils of wire and iron built up into electro-magnets. I know well the impression it made on the average spectator, for I have been occupied in experiments of this kind nearly all my life, notwithstanding the advice, given in perfect good faith, by non-scientific visitors to the laboratory, to put that aside and spend my time on something useful.

Cosmology is a science which has only a few observable facts to work with. The discovery of the cosmic microwave background radiation added one—the present radiation temperature of the universe. This, however, was a significant increase in our knowledge since it requires a cosmology with a source for the radiation at an early epoch and is a new probe of that epoch. More sensitive measurements of the background radiation in the future will allow us to discover additional facts about the universe.

DOCTOR. Always preceded by “The good”. Among men, in familiar conversation, “Oh! balls, doctor!” Is a wizard when he enjoys your confidence, a jack-ass when you're no longer on terms. All are materialists: “you can't probe for faith with a scalpel.”

Having probes in space was like having a cataract removed. We could see things never seen before, just as Galileo could with his telescope.

It is not necessary to probe into the nature of things, as was done by those whom the Greeks call physici; nor need we be in alarm lest the Christian should be ignorant of the force and number of the elements—the motion, and order, and eclipses of the heavenly bodies; the form of the heavens; the species and the natures of animals, plants, stones, fountains, rivers, mountains; about chronology and distances; the signs of coming storms; and a thousand other things which those philosophers either have found out, or think they have found out. … It is enough for the Christian to believe that the only cause of all created things, whether heavenly or earthly … is the goodness of the Creator, the one true God.

Physicist Isador Isaac Rabi, who won a Nobel Prize for inventing a technique that permitted scientists to probe the structure of atoms and molecules in the 1930s, attributed his success to the way his mother used to greet him when he came home from school each day. “Did you ask any good questions today, Isaac?” she would say.

Science is in a literal sense constructive of new facts. It has no fixed body of facts passively awaiting explanation, for successful theories allow the construction of new instruments—electron microscopes and deep space probes—and the exploration of phenomena that were beyond description—the behavior of transistors, recombinant DNA, and elementary particles, for example. This is a key point in the progressive nature of science—not only are there more elegant or accurate analyses of phenomena already known, but there is also extension of the range of phenomena that exist to be described and explained.
Co-author with Michael A. Arbib, English-born professor of computer science and biomedical engineering (1940-)

When they [radio astronomers] grew weary at their electronic listening posts. When their eyes grew dim with looking at unrevealing dials and studying uneventful graphs, they could step outside their concrete cells and renew their dull spirits in communion with the giant mechanism they commanded, the silent, sensing instrument in which the smallest packets of energy, the smallest waves of matter, were detected in their headlong, eternal flight across the universe. It was the stethoscope with which they took the pulse of the all and noted the birth and death of stars, the probe which, here on an insignificant planet of an undistinguishable star on the edge of its galaxy, they explored the infinite.