Art creates an incomparable and unique effect, and, having done so, passes on to other things. Nature, upon the other hand, forgetting that imitation can be made the sincerest form of insult, keeps on repeating the effect until we all become absolutely wearied of it.

Endowed with two qualities, which seemed incompatible with each other, a volcanic imagination and a pertinacity of intellect which the most tedious numerical calculations could not daunt, Kepler conjectured that the movements of the celestial bodies must be connected together by simple laws, or, to use his own expression, by harmonic laws. These laws he undertook to discover. A thousand fruitless attempts, errors of calculation inseparable from a colossal undertaking, did not prevent him a single instant from advancing resolutely toward the goal of which he imagined he had obtained a glimpse. Twenty-two years were employed by him in this investigation, and still he was not weary of it! What, in reality, are twenty-two years of labor to him who is about to become the legislator of worlds; who shall inscribe his name in ineffaceable characters upon the frontispiece of an immortal code; who shall be able to exclaim in dithyrambic language, and without incurring the reproach of anyone, “The die is cast; I have written my book; it will be read either in the present age or by posterity, it matters not which; it may well await a reader, since God has waited six thousand years for an interpreter of his words.”

Governments of the Industrial World, you weary giants of flesh and steel, I come from Cyberspace, the new home of Mind. On behalf of the future, I ask you of the past to leave us alone. You are not welcome among us. You have no sovereignty where we gather.

I trust ... I have succeeded in convincing you that modern chemistry is not, as it has so long appeared, an ever-growing accumulation of isolated facts, as impossible for a single intellect to co-ordinate as for a single memory to grasp.
The intricate formulae that hang upon these walls, and the boundless variety of phenomena they illustrate, are beginning to be for us as a labyrinth once impassable, but to which we have at length discovered the clue. A sense of mastery and power succeeds in our minds to the sort of weary despair with which we at first contemplated their formidable array. For now, by the aid of a few general principles, we find ourselves able to unravel the complexities of these formulae, to marshal the compounds which they represent in orderly series; nay, even to multiply their numbers at our will, and in a great measure to forecast their nature ere we have called them into existence. It is the great movement of modern chemistry that we have thus, for an hour, seen passing before us. It is a movement as of light spreading itself over a waste of obscurity, as of law diffusing order throughout a wilderness of confusion, and there is surely in its contemplation something of the pleasure which attends the spectacle of a beautiful daybreak, something of the grandeur belonging to the conception of a world created out of chaos.

Is this your triumph—this your proud applause,
Children of Truth, and champions of her cause?
For this has Science search’d, on weary wing,
By shore and sea—each mute and living thing!

Oh God! that one might read the book of fate,
And see the revolution of the times
Make mountains level, and the continent,
Weary of solid firmness, melt itself
Into the sea.

There is no record in human history of a happy philosopher; they exist only in romantic legend. Many of them have committed suicide; many others have turned their children out of doors and beaten their wives. And no wonder. If you want to find out how a philosopher feels when he is engaged in the practise of his profession, go to the nearest zoo and watch a chimpanzee at the wearying and hopeless job of chasing fleas. Both suffer damnably, and neither can win.

Those who dwell as scientists … among the beauties and mysteries of the earth are never alone or weary of life. Those who contemplate the beauty of the earth find reserves of strength that will endure as long as life lasts.

Those who judge of a work by rule are in regard to others as those who have a watch are in regard to others. One says, “It is two hours ago”; the other says, “It is only three-quarters of an hour.” I look at my watch, and say to the one, “You are weary,” and to the other, “Time gallops with you”; for it is only an hour and a half ago, and I laugh at those who tell me that time goes slowly with me, and that I judge by imagination. They do not know that I judge by my watch.

Twice in my life I have spent two weary and scientifically profitless years seeking evidence to corroborate dearly loved hypotheses that later proved to be groundless; times such as these are hard for scientists—days of leaden gray skies bringing with them a miserable sense of oppression and inadequacy.

When they [radio astronomers] grew weary at their electronic listening posts. When their eyes grew dim with looking at unrevealing dials and studying uneventful graphs, they could step outside their concrete cells and renew their dull spirits in communion with the giant mechanism they commanded, the silent, sensing instrument in which the smallest packets of energy, the smallest waves of matter, were detected in their headlong, eternal flight across the universe. It was the stethoscope with which they took the pulse of the all and noted the birth and death of stars, the probe which, here on an insignificant planet of an undistinguishable star on the edge of its galaxy, they explored the infinite.