An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going. But this should not be taken to imply that there are good reasons to believe that it could not have started on the earth by a perfectly reasonable sequence of fairly ordinary chemical reactions. The plain fact is that the time available was too long, the many microenvironments on the earth’s surface too diverse, the various chemical possibilities too numerous and our own knowledge and imagination too feeble to allow us to be able to unravel exactly how it might or might not have happened such a long time ago, especially as we have no experimental evidence from that era to check our ideas against.

Any true Sherlock Holmes of science, possest of an adequate knowledge of first principles, may unravel a very tangled web of mystery. The great naturalist requires but a few pieces of bone from any prehistoric monster in order to ascertain whether it was herbivorous or carnivorous, reptile or mammal, or even to construct a counterpart of its entire skeleton.

At terrestrial temperatures matter has complex properties which are likely to prove most difficult to unravel; but it is reasonable to hope that in the not too distant future we shall be competent to understand so simple a thing as a star.

I trust ... I have succeeded in convincing you that modern chemistry is not, as it has so long appeared, an ever-growing accumulation of isolated facts, as impossible for a single intellect to co-ordinate as for a single memory to grasp.
The intricate formulae that hang upon these walls, and the boundless variety of phenomena they illustrate, are beginning to be for us as a labyrinth once impassable, but to which we have at length discovered the clue. A sense of mastery and power succeeds in our minds to the sort of weary despair with which we at first contemplated their formidable array. For now, by the aid of a few general principles, we find ourselves able to unravel the complexities of these formulae, to marshal the compounds which they represent in orderly series; nay, even to multiply their numbers at our will, and in a great measure to forecast their nature ere we have called them into existence. It is the great movement of modern chemistry that we have thus, for an hour, seen passing before us. It is a movement as of light spreading itself over a waste of obscurity, as of law diffusing order throughout a wilderness of confusion, and there is surely in its contemplation something of the pleasure which attends the spectacle of a beautiful daybreak, something of the grandeur belonging to the conception of a world created out of chaos.

Learning how to access a continuity of common sense can be one of your most efficient accomplishments in this decade. Can you imagine common sense surpassing science and technology in the quest to unravel the human stress mess? In time, society will have a new measure for confirming truth. It’s inside the people-not at the mercy of current scientific methodology. Let scientists facilitate discovery, but not invent your inner truth.

Mere infants of the universe, with no feel for infinity, no sense of place in time and space, we human beings have yet to comprehend the enormity of what we are doing: In a geological second, we are unraveling complexities it took eternity to create.

The greatest enemy, however, to true arithmetic work is found in so-called practical or illustrative problems, which are freely given to our pupils, of a degree of difficulty and complexity altogether unsuited to their age and mental development. … I am, myself, no bad mathematician, and all the reasoning powers with which nature endowed me have long been as fully developed as they are ever likely to be; but I have, not infrequently, been puzzled, and at times foiled, by the subtle logical difficulty running through one of these problems, given to my own children. The head-master of one of our Boston high schools confessed to me that he had sometimes been unable to unravel one of these tangled skeins, in trying to help his own daughter through her evening’s work. During this summer, Dr. Fairbairn, the distinguished head of one of the colleges of Oxford, England, told me that not only had he himself encountered a similar difficulty, in the case of his own children, but that, on one occasion, having as his guest one of the first mathematicians of England, the two together had been completely puzzled by one of these arithmetical conundrums.

The origin and the causes of disease are far too recondite for the human mind to unravel them.

The quantum is that embarrassing little piece of thread that always hangs from the sweater of space-time. Pull it and the whole thing unravels.

The truly awesome intellectuals in our history have not merely made discoveries; they have woven variegated, but firm, tapestries of comprehensive coverage. The tapestries have various fates: Most burn or unravel in the foot steps of time and the fires of later discovery. But their glory lies in their integrity as unified structures of great complexity and broad implication.

Through the naturalist’s eyes, a sparrow can be as interesting as a bird of paradise, the behaviour of a mouse as interesting as that of a tiger, and a humble lizard as fascinating as a crocodile. … Our planet is beautifully intricate, brimming over with enigmas to be solved and riddles to be unravelled.

Time is in itself [not] a difficulty, but a time-rate, assumed on very insufficient grounds, is used as a master-key, whether or not it fits, to unravel all difficulties. What if it were suggested that the brick-built Pyramid of Hawara had been laid brick by brick by a single workman? Given time, this would not be beyond the bounds of possibility. But Nature, like the Pharaohs, had greater forces at her command to do the work better and more expeditiously than is admitted by Uniformitarians.

Unless there exist peculiar institutions for the support of such inquirers, or unless the Government directly interfere, the contriver of a thaumatrope may derive profit from his ingenuity, whilst he who unravels the laws of light and vision, on which multitudes of phenomena depend, shall descend unrewarded to the tomb.

What a deep faith in the rationality of the structure of the world and what a longing to understand even a small glimpse of the reason revealed in the world there must have been in Kepler and Newton to enable them to unravel the mechanism of the heavens in long years of lonely work!

What we still designate as chance, merely depends on a concatenation of circumstances, the internal connection and final causes of which we have as yet been unable to unravel.

Whatever the subject of any investigation may be, whether poetry, biology, ethics or torpedo warfare, the same scientific method of procedure must be followed. We must first unravel the complex and heterogeneous back to first principles, and then reason forward from the simple to the complex, from the homogeneous to the heterogeneous, from what we know to what we would learn. Such are the methods pursued by all successful inventors, scientific investigators and discoverers.