… certain conditions under which the observable thing is perceived are tacitly assumed ... for the possibility that we deal with hallucinations or a dream can never be excluded.

… it may happen that small differences in the initial conditions produce very great ones in the final phenomena.

…it ought to be remembered that there is nothing more difficult to take in hand, more perilous to conduct, or more uncertain in its success, than to take the lead in the introduction of a new order of things. Because the innovator has for enemies all those who have done well under the old conditions, and lukewarm defenders in those who may do well under the new.

...the life of the planet began the long, slow process of modulating and regulating the physical conditions of the planet. The oxygen in today's atmosphere is almost entirely the result of photosynthetic living, which had its start with the appearance of blue-green algae among the microorganisms.

“Men die of the diseases which they have studied most,” remarked the surgeon, snipping off the end of a cigar with all his professional neatness and finish. “It’s as if the morbid condition was an evil creature which, when it found itself closely hunted, flew at the throat of its pursuer. If you worry the microbes too much they may worry you. I’ve seen cases of it, and not necessarily in microbic diseases either. There was, of course, the well-known instance of Liston and the aneurism; and a dozen others that I could mention.”

[A]s you know, scientific education is fabulously neglected … This is an evil that is inherited, passed on from generation to generation. The majority of educated persons are not interested in science, and are not aware that scientific knowledge forms part of the idealistic background of human life. Many believe—in their complete ignorance of what science really is—that it has mainly the ancillary task of inventing new machinery, or helping to invent it, for improving our conditions of life. They are prepared to leave this task to the specialists, as they leave the repairing of their pipes to the plumber. If persons with this outlook decide upon the curriculum of our children, the result is necessarily such as I have just described it.

[An audience conditioned by a lifetime of television-watching is so corrupted that] their standards have been systematically lowered over the years. These guys sit in front of their sets and the gamma rays eat the white cells of their brains out!

[Certain students] suppose that because science has penetrated the structure of the atom it can solve all the problems of the universe. ... They are known in every ... college as the most insufferable, cocksure know-it-alls. If you want to talk to them about poetry, they are likely to reply that the "emotive response" to poetry is only a conditioned reflex .... If they go on to be professional scientists, their sharp corners are rubbed down, but they undergo no fundamental change. They most decidedly are not set apart from the others by their intellectual integrity and faith, and their patient humility in front of the facts of nature.... They are uneducated, in the fullest sense of the word, and they certainly are no advertisement for the claims of science teachers.

[Having already asserted his opposition to communism in every respect by signing the regents' oath, his answer to a question why a non-Communist professor should refuse to take a non-Communist oath as a condition of University employment was that to do so would imply it was] up to an accused person to clear himself. ... That sort of thing is going on in Washington today and is a cause of alarm to thoughtful citizens. It is the method used in totalitarian countries. It sounds un-American to people who don’t like to be pushed around. If someone says I ought to do a certain thing the burden should be on him to show I why I should, not on me to show why I should not.

[Janos] Bolyai when in garrison with cavalry officers, was provoked by thirteen of them and accepted all their challenges on condition that he be permitted after each duel to play a bit on his violin. He came out victor from his thirteen duels, leaving his thirteen adversaries on the square.

[To the cultures of Asia and the continent of Africa] it is the Western impact which has stirred up the winds of change and set the processes of modernization in motion. Education brought not only the idea of equality but also another belief which we used to take for granted in the West—the idea of progress, the idea that science and technology can be used to better human conditions. In ancient society, men tended to believe themselves fortunate if tomorrow was not worse than today and anyway, there was little they could do about it.

'Causation' has been popularly used to express the condition of association, when applied to natural phenomena. There is no philosophical basis for giving it a wider meaning than partial or absolute association. In no case has it been proved that there is an inherent necessity in the laws of nature. Causation is correlation... [P]erfect correlation, when based upon sufficient experience, is causation in the scientific sense.

“Pieces” almost always appear 'as parts' in whole processes. ... To sever a “'part” from the organized whole in which it occurs—whether it itself be a subsidiary whole or an “element”—is a very real process usually involving alterations in that “part”. Modifications of a part frequently involve changes elsewhere in the whole itself. Nor is the nature of these alterations arbitrary, for they too are determined by whole-conditions.

Die Religion ist der Seufzer der bedrängten Kreatur, das Gemüt einer herzlosen Welt, wie sie der Geist geistloser Zustände ist. Sie ist das Opium des Volks. Die Aufhebung der Religion als des illusorischen Glücks des Volks ist die Forderung seines wirklichen Glücks.
Religion is the sigh of the oppressed creature, the heart of a heartless world, just as it is the spirit of spiritless conditions. It is the opium of the people. To abolish religion as the illusory happiness of the people is to demand their real happiness.

Question: State what are the conditions favourable for the formation of dew. Describe an instrument for determining the dew point, and the method of using it.
Answer: This is easily proved from question 1. A body of gas as it ascends expands, cools, and deposits moisture; so if you walk up a hill the body of gas inside you expands, gives its heat to you, and deposits its moisture in the form of dew or common sweat. Hence these are the favourable conditions; and moreover it explains why you get warm by ascending a hill, in opposition to the well-known law of the Conservation of Energy.

The constancy of the internal environment is the condition for free and independent life: the mechanism that makes it possible is that which assured the maintenance, with the internal environment, of all the conditions necessary for the life of the elements.

~~[Misattributed]~~ Time and space are modes by which we think and not conditions in which we live.

A chemical compound once formed would persist for ever, if no alteration took place in surrounding conditions. But to the student of Life the aspect of nature is reversed. Here, incessant, and, so far as we know, spontaneous change is the rule, rest the exception—the anomaly to be accounted for. Living things have no inertia and tend to no equilibrium.

A good physiological experiment like a good physical one requires that it should present anywhere, at any time, under identical conditions, the same certain and unequivocal phenomena that can always be confirmed.

A laboratory is only a place where one may better set up and control conditions.

A modern branch of mathematics, having achieved the art of dealing with the infinitely small, can now yield solutions in other more complex problems of motion, which used to appear insoluble. This modern branch of mathematics, unknown to the ancients, when dealing with problems of motion, admits the conception of the infinitely small, and so conforms to the chief condition of motion (absolute continuity) and thereby corrects the inevitable error which the human mind cannot avoid when dealing with separate elements of motion instead of examining continuous motion. In seeking the laws of historical movement just the same thing happens. The movement of humanity, arising as it does from innumerable human wills, is continuous. To understand the laws of this continuous movement is the aim of history. … Only by taking an infinitesimally small unit for observation (the differential of history, that is, the individual tendencies of man) and attaining to the art of integrating them (that is, finding the sum of these infinitesimals) can we hope to arrive at the laws of history.

A philosopher once said, “It is necessary for the very existence of science that the same conditions always produce the same results”. Well, they do not.

A physician’s subject of study is necessarily the patient, and his first field for observation is the hospital. But if clinical observation teaches him to know the form and course of diseases, it cannot suffice to make him understand their nature; to this end he must penetrate into the body to find which of the internal parts are injured in their functions. That is why dissection of cadavers and microscopic study of diseases were soon added to clinical observation. But to-day these various methods no longer suffice; we must push investigation further and, in analyzing the elementary phenomena of organic bodies, must compare normal with abnormal states. We showed elsewhere how incapable is anatomy alone to take account of vital phenenoma, and we saw that we must add study of all physico-chemical conditions which contribute necessary elements to normal or pathological manifestations of life. This simple suggestion already makes us feel that the laboratory of a physiologist-physician must be the most complicated of all laboratories, because he has to experiment with phenomena of life which are the most complex of all natural phenomena.

A proposal…to bore a hole in the crust of the Earth and discover the conditions deep down below the surface…may remind us that the most secret places of Nature are, perhaps, not 10 to the n-th miles above our heads, but 10 miles below our feet.

A single tree by itself is dependent upon all the adverse chances of shifting circumstances. The wind stunts it: the variations in temperature check its foliage: the rains denude its soil: its leaves are blown away and are lost for the purpose of fertilisation. You may obtain individual specimens of line trees either in exceptional circumstances, or where human cultivation had intervened. But in nature the normal way in which trees flourish is by their association in a forest. Each tree may lose something of its individual perfection of growth, but they mutually assist each other in preserving the conditions of survival. The soil is preserved and shaded; and the microbes necessary for its fertility are neither scorched, nor frozen, nor washed away. A forest is the triumph of the organisation of mutually dependent species.

A week or so after I learned that I was to receive the Miller Award, our president, Marty Morton, phoned and asked me if I would utter a few words of scientific wisdom as a part of the ceremony. Unfortunately for me, and perhaps for you, I agreed to do so. In retrospect I fear that my response was a serious error, because I do not feel wise. I do not know whether to attribute my response to foolhardiness, to conceit, to an inordinate susceptibility to flattery, to stupidity, or to some combination of these unfortunate attributes all of which I have been told are recognizable in my personality. Personally, I tend to favor stupidity, because that is a condition over which I have little control.

According to my derivative hypothesis, a change takes place first in the structure of the animal, and this, when sufficiently advanced, may lead to modifications of habits… . “Derivation” holds that every species changes, in time, by virtue of inherent tendencies thereto. “Natural Selection” holds that no such change can take place without the influence of altered external circumstances educing or selecting such change… . The hypothesis of “natural selection” totters on the extension of a conjectural condition, explanatory of extinction to the majority of organisms, and not known or observed to apply to the origin of any species.

After having produced aquatic animals of all ranks and having caused extensive variations in them by the different environments provided by the waters, nature led them little by little to the habit of living in the air, first by the water's edge and afterwards on all the dry parts of the globe. These animals have in course of time been profoundly altered by such novel conditions; which so greatly influenced their habits and organs that the regular gradation which they should have exhibited in complexity of organisation is often scarcely recognisable.

All fossil anthropoids found hitherto have been known only from mandibular or maxillary fragments, so far as crania are concerned, and so the general appearance of the types they represented had been unknown; consequently, a condition of affairs where virtually the whole face and lower jaw, replete with teeth, together with the major portion of the brain pattern, have been preserved, constitutes a specimen of unusual value in fossil anthropoid discovery. Here, as in Homo rhodesiensis, Southern Africa has provided documents of higher primate evolution that are amongst the most complete extant. Apart from this evidential completeness, the specimen is of importance because it exhibits an extinct race of apes intermediate between living anthropoids and man ... Whether our present fossil is to be correlated with the discoveries made in India is not yet apparent; that question can only be solved by a careful comparison of the permanent molar teeth from both localities. It is obvious, meanwhile, that it represents a fossil group distinctly advanced beyond living anthropoids in those two dominantly human characters of facial and dental recession on one hand, and improved quality of the brain on the other. Unlike Pithecanthropus, it does not represent an ape-like man, a caricature of precocious hominid failure, but a creature well advanced beyond modern anthropoids in just those characters, facial and cerebral, which are to be anticipated in an extinct link between man and his simian ancestor. At the same time, it is equally evident that a creature with anthropoid brain capacity and lacking the distinctive, localised temporal expansions which appear to be concomitant with and necessary to articulate man, is no true man. It is therefore logically regarded as a man-like ape. I propose tentatively, then, that a new family of Homo-simidæ be created for the reception of the group of individuals which it represents, and that the first known species of the group be designated Australopithecus africanus, in commemoration, first, of the extreme southern and unexpected horizon of its discovery, and secondly, of the continent in which so many new and important discoveries connected with the early history of man have recently been made, thus vindicating the Darwinian claim that Africa would prove to be the cradle of mankind.

All great achievements in science start from intuitive knowledge, namely, in axioms, from which deductions are then made. … Intuition is the necessary condition for the discovery of such axioms.

All men and women are born, live suffer and die; what distinguishes us one from another is our dreams, whether they be dreams about worldly or unworldly things, and what we do to make them come about... We do not choose to be born. We do not choose our parents. We do not choose our historical epoch, the country of our birth, or the immediate circumstances of our upbringing. We do not, most of us, choose to die; nor do we choose the time and conditions of our death. But within this realm of choicelessness, we do choose how we live.

All parts of the material universe are in constant motion and though some of the changes may appear to be cyclical, nothing ever exactly returns, so far as human experience extends, to precisely the same condition.

All sedentary workers ... suffer from the itch, are a bad colour, and in poor condition ... for when the body is not kept moving the blood becomes tainted, its waste matter lodges in the skin, and the condition of the whole body deteriorates. (1700)

All the conditions of happiness are realized in the life of the man of science.

All things appear and disappear because of the concurrence of causes and conditions. Nothing ever exists entirely alone; everything is in relationship to everything else.

Almost every major systematic error which has deluded men for thousands of years relied on practical experience. Horoscopes, incantations, oracles, magic, witchcraft, the cures of witch doctors and of medical practitioners before the advent of modern medicine, were all firmly established through the centuries in the eyes of the public by their supposed practical successes. The scientific method was devised precisely for the purpose of elucidating the nature of things under more carefully controlled conditions and by more rigorous criteria than are present in the situations created by practical problems.

Among all highly civilized peoples the golden age of art has always been closely coincident with the golden age of the pure sciences, particularly with mathematics, the most ancient among them.
This coincidence must not be looked upon as accidental, but as natural, due to an inner necessity. Just as art can thrive only when the artist, relieved of the anxieties of existence, can listen to the inspirations of his spirit and follow in their lead, so mathematics, the most ideal of the sciences, will yield its choicest blossoms only when life’s dismal phantom dissolves and fades away, when the striving after naked truth alone predominates, conditions which prevail only in nations while in the prime of their development.

An amoeba never is torn apart through indecision, though, for even if two parts of the amoeba are inclined to go in different directions, a choice is always made. We could interpret this as schizophrenia or just confusion, but it could also be a judicious simultaneous sampling of conditions, in order to make a wise choice of future direction.

An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going. But this should not be taken to imply that there are good reasons to believe that it could not have started on the earth by a perfectly reasonable sequence of fairly ordinary chemical reactions. The plain fact is that the time available was too long, the many microenvironments on the earth’s surface too diverse, the various chemical possibilities too numerous and our own knowledge and imagination too feeble to allow us to be able to unravel exactly how it might or might not have happened such a long time ago, especially as we have no experimental evidence from that era to check our ideas against.

And if this were so in all cases, the principle would be established, that sometimes conditions can be treated by things opposite to those from which they arose, and sometimes by things like to those from which they arose.

And when statesmen or others worry him [the scientist] too much, then he should leave with his possessions. With a firm and steadfast mind one should hold under all conditions, that everywhere the earth is below and the sky above and to the energetic man, every region is his fatherland.

Any experiment may be regarded as forming an individual of a 'population' of experiments which might be performed under the same conditions. A series of experiments is a sample drawn from this population.
Now any series of experiments is only of value in so far as it enables us to form a judgment as to the statistical constants of the population to which the experiments belong. In a great number of cases the question finally turns on the value of a mean, either directly, or as the mean difference between the two qualities.
If the number of experiments be very large, we may have precise information as to the value of the mean, but if our sample be small, we have two sources of uncertainty:— (I) owing to the 'error of random sampling' the mean of our series of experiments deviates more or less widely from the mean of the population, and (2) the sample is not sufficiently large to determine what is the law of distribution of individuals.

Anyone of common mental and physical health can practice scientific research. … Anyone can try by patient experiment what happens if this or that substance be mixed in this or that proportion with some other under this or that condition. Anyone can vary the experiment in any number of ways. He that hits in this fashion on something novel and of use will have fame. … The fame will be the product of luck and industry. It will not be the product of special talent.

Apart from the hostile influence of man, the organic and the inorganic world are … bound together by such mutual relations and adaptations as secure, if not the absolute permanence and equilibrium of both … at least a very slow and gradual succession of changes in those conditions. But man is everywhere a disturbing agent. Wherever he plants his foot, the harmonies of nature are turned to discords.

As geologists, we learn that it is not only the present condition of the globe that has been suited to the accommodation of myriads of living creatures, but that many former states also have been equally adapted to the organization and habits of prior races of beings. The disposition of the seas, continents, and islands, and the climates have varied; so it appears that the species have been changed, and yet they have all been so modelled, on types analogous to those of existing plants and animals, as to indicate throughout a perfect harmony of design and unity of purpose. To assume that the evidence of the beginning or end of so vast a scheme lies within the reach of our philosophical inquiries, or even of our speculations, appears to us inconsistent with a just estimate of the relations which subsist between the finite powers of man and the attributes of an Infinite and Eternal Being.

As he [Clifford] spoke he appeared not to be working out a question, but simply telling what he saw. Without any diagram or symbolic aid he described the geometrical conditions on which the solution depended, and they seemed to stand out visibly in space. There were no longer consequences to be deduced, but real and evident facts which only required to be seen. … So whole and complete was his vision that for the time the only strange thing was that anybody should fail to see it in the same way. When one endeavored to call it up again, and not till then, it became clear that the magic of genius had been at work, and that the common sight had been raised to that higher perception by the power that makes and transforms ideas, the conquering and masterful quality of the human mind which Goethe called in one word das Dämonische.

As soon as the circumstances of an experiment are well known, we stop gathering statistics. … The effect will occur always without exception, because the cause of the phenomena is accurately defined. Only when a phenomenon includes conditions as yet undefined,Only when a phenomenon includes conditions as yet undefined, can we compile statistics. … we must learn therefore that we compile statistics only when we cannot possibly help it; for in my opinion, statistics can never yield scientific truth.

As to what Simplicius said last, that to contend whether the parts of the Sun, Moon, or other celestial body, separated from their whole, should naturally return to it, is a vanity, for that the case is impossible, it being clear by the demonstrations of Aristotle that the celestial bodies are impassible, impenetrable, unpartable, etc., I answer that none of the conditions whereby Aristotle distinguishes the celestial bodies from the elementary has any foundation other than what he deduces from the diversity of their natural motions; so that, if it is denied that the circular motion is peculiar to celestial bodies, and affirmed instead that it is agreeable to all naturally moveable bodies, one is led by necessary confidence to say either that the attributes of generated or ungenerated, alterable or unalterable, partable or unpartable, etc., equally and commonly apply to all bodies, as well to the celestial as to the elementary, or that Aristotle has badly and erroneously deduced those from the circular motion which he has assigned to celestial bodies.

As usual, the author in his thorough, unobjective fashion has marshalled up all the good, indifferent and bad arguments ... I offer the following detailed comments ... though I realize that many of them will arouse him to a vigorous, if not violent rebuttal. In order to preserve the pH of Dr. Brown's digestive system I would not require a rebuttal as a condition of publication...
With heartiest greetings of the season to you and yours! Jack Roberts
PS The above comments should (help) to reduce your winter heating bill!
Jack Roberts' referee's report on Herbert Charles Brown's paper with Rachel Kornblum on the role of steric strain in carbonium ion reactions.

Astronomy, as the science of cyclical motions, has nothing in common with Geology. But look at Astronomy where she has an analogy with Geology; consider our knowledge of the heavens as a palaetiological science;—as the study of a past condition, from which the present is derived by causes acting in time. Is there no evidence of a beginning, or of a progress?

Bacteria are highly adaptable. They frequently change both morphologically and functionally. Their virulence is also an essentially fluctuating property, that increases or diminishes according to the conditions to which the pathogenic organism is subjected.

Biologists have long attempted by chemical means to induce in higher organisms predictable and specific changes which thereafter could be transmitted in series as hereditary characters. Among microorganisms the most striking example of inheritable and specific alterations in cell structure and function that can be experimentally induced and are reproducible under well defined and adequately controlled conditions is the transformation of specific types of Pneumococcus.

Blaming others, or outside conditions for one’s own misbehavior may be the child’s privilege; if an adult denies responsibility for his actions, it is another step towards personality disintegration.

But weightier still are the contentment which comes from work well done, the sense of the value of science for its own sake, insatiable curiosity, and, above all, the pleasure of masterly performance and of the chase. These are the effective forces which move the scientist. The first condition for the progress of science is to bring them into play.

But, further, no animal can live upon a mixture of pure protein, fat and carbohydrate, and even when the necessary inorganic material is carefully supplied, the animal still cannot flourish. The animal body is adjusted to live either upon plant tissues or the tissues of other animals, and these contain countless substances other than the proteins, carbohydrates and fats... In diseases such as rickets, and particularly in scurvy, we have had for long years knowledge of a dietetic factor; but though we know how to benefit these conditions empirically, the real errors in the diet are to this day quite obscure. They are, however, certainly of the kind which comprises these minimal qualitative factors that I am considering.

By considering the embryological structure of man - the homologies which he presents with the lower animals - the rudiments which he retains - and the reversions to which he is liable, we can partly recall in imagination the former condition of our early progenitors; and we can approximately place them in their proper position in the zoological series. We thus learnt that man is descended from a hairy quadruped, furnished with a tail and pointed ears, probably arboreal in its habit, and an inhabitant of the Old World. This creature, if its whole structure had been examined by a naturalist, would have been classed among the Quadrumana, as surely as would be the common and still more ancient progenitor of the Old and New World monkeys.

By natural selection our mind has adapted itself to the conditions of the external world. It has adopted the geometry most advantageous to the species or, in other words, the most convenient. Geometry is not true, it is advantageous.

Can one think that because we are engineers, beauty does not preoccupy us or that we do not try to build beautiful, as well as solid and long lasting structures? Aren’t the genuine functions of strength always in keeping with unwritten conditions of harmony? … Besides, there is an attraction, a special charm in the colossal to which ordinary theories of art do not apply.

Certainty is the most vivid condition of ignorance and the most necessary condition for knowledge.

Chance throws peculiar conditions in everyone's way. If we apply intelligence, patience and special vision, we are rewarded with new creative breakthroughs.

Conditions for creativity are to be puzzled; to concentrate; to accept conflict and tension; to be born everyday; to feel a sense of self.

Consider the plight of a scientist of my age. I graduated from the University of California at Berkeley in 1940. In the 41 years since then the amount of biological information has increased 16 fold; during these 4 decades my capacity to absorb new information has declined at an accelerating rate and now is at least 50% less than when I was a graduate student. If one defines ignorance as the ratio of what is available to be known to what is known, there seems no alternative to the conclusion that my ignorance is at least 25 times as extensive as it was when I got my bachelor’s degree. Although I am sure that my unfortunate condition comes as no surprise to my students and younger colleagues, I personally find it somewhat depressing. My depression is tempered, however, by the fact that all biologists, young or old, developing or senescing, face the same melancholy situation because of an interlocking set of circumstances.

Considering the difficulties represented by the lack of water, by extremes of temperature, by the full force of gravity unmitigated by the buoyancy of water, it must be understood that the spread to land of life forms that evolved to meet the conditions of the ocean represented the greatest single victory won by life over the inanimate environment.

Constant, or free, life is the third form of life; it belongs to the most highly organized animals. In it, life is not suspended in any circumstance, it unrolls along a constant course, apparently indifferent to the variations in the cosmic environment, or to the changes in the material conditions that surround the animal. Organs, apparatus, and tissues function in an apparently uniform manner, without their activity undergoing those considerable variations exhibited by animals with an oscillating life. This because in reality the internal environment that envelops the organs, the tissues, and the elements of the tissues does not change; the variations in the atmosphere stop there, so that it is true to say that physical conditions of the environment are constant in the higher animals; it is enveloped in an invariable medium, which acts as an atmosphere of its own in the constantly changing cosmic environment. It is an organism that has placed itself in a hot-house. Thus the perpetual changes in the cosmic environment do not touch it; it is not chained to them, it is free and independent.

Courtship, properly understood, is the process whereby both the male and the female are brought into that state of sexual tumescence which is a more or less necessary condition for sexual intercourse. The play of courtship cannot, therefore, be considered to be definitely brought to an end by the ceremony of marriage; it may more properly be regarded as the natural preliminary to every act of coitus.

Culture in its higher forms is a delicate plant which depends on a complicated set of conditions and is wont to flourish only in a few places at any given time.

Disease is largely a removable evil. It continues to afflict humanity, not only because of incomplete knowledge of its causes and lack of individual and public hygiene, but also because it is extensively fostered by harsh economic and industrial conditions and by wretched housing in congested communities. ... The reduction of the death rate is the principal statistical expression and index of human social progress. It means the saving and lengthening of lives of thousands of citizens, the extension of the vigorous working period well into old age, and the prevention of inefficiency, misery, and suffering. These advances can be made by organized social effort. Public health is purchasable. (1911)

Disease is not something personal and special, but only a manifestation of life under modified conditions, operating according to the same laws as apply to the living body at all times, from the first moment until death.

Does life belong to what we know as matter, or is it an independent principle inserted into matter at some suitable epoch when the physical conditions became such as to permit the development of life?

Dreams are renewable. No matter what our age or condition, there are still untapped possibilities within us and new beauty waiting to be born.

During cycles long anterior to the creation of the human race, and while the surface of the globe was passing from one condition to another, whole races of animals–each group adapted to the physical conditions in which they lived–were successively created and exterminated.

Ecological differentiation is the necessary condition for coexistence.

Education, then, beyond all other devices of human origin, is the great equalizer of the conditions of men–the balance-wheel of the social machinery.

Effects vary with the conditions which bring them to pass, but laws do not vary. Physiological and pathological states are ruled by the same forces; they differ only because of the special conditions under which the vital laws manifest themselves.

Engineering is the science and art of efficient dealing with materials and forces … it involves the most economic design and execution … assuring, when properly performed, the most advantageous combination of accuracy, safety, durability, speed, simplicity, efficiency, and economy possible for the conditions of design and service.

Ere long intelligence—transmitted without wires—will throb through the earth like a pulse through a living organism. The wonder is that, with the present state of knowledge and the experiences gained, no attempt is being made to disturb the electrostatic or magnetic condition of the earth, and transmit, if nothing else, intelligence.

Even today a good many distinguished minds seem unable to accept or even to understand that from a source of noise natural selection alone and unaided could have drawn all the music of the biosphere. In effect natural selection operates upon the products of chance and can feed nowhere else; but it operates in a domain of very demanding conditions, and from this domain chance is barred. It is not to chance but to these conditions that eveloution owes its generally progressive cource, its successive conquests, and the impresssion it gives of a smooth and steady unfolding.

Every complete set of chromosomes contains the full code; so there are, as a rule, two copies of the latter in the fertilized egg cell, which forms the earliest stage of the future individual. In calling the structure of the chromosome fibres a code-script we mean that the all-penetrating mind, once conceived by Laplace, to which every causal connection lay immediately open, could tell from their structure whether the egg would develop, under suitable conditions, into a black cock or into a speckled hen, into a fly or a maize plant, a rhododendron, a beetle, a mouse or a woman. To which we may add, that the appearances of the egg cells are very often remarkably similar; and even when they are not, as in the case of the comparatively gigantic eggs of birds and reptiles, the difference is not so much in the relevant structures as in the nutritive material which in these cases is added for obvious reasons.
But the term code-script is, of course, too narrow. The chromosome structures are at the same time instrumental in bringing about the development they foreshadow. They are law-code and executive power?or, to use another simile, they are architect's plan and builder’s craft-in one.

Experiments may be of two kinds: experiments of simple fact, and experiments of quantity. ...[In the latter] the conditions will ... vary, not in quality, but quantity, and the effect will also vary in quantity, so that the result of quantitative induction is also to arrive at some mathematical expression involving the quantity of each condition, and expressing the quantity of the result. In other words, we wish to know what function the effect is of its conditions. We shall find that it is one thing to obtain the numerical results, and quite another thing to detect the law obeyed by those results, the latter being an operation of an inverse and tentative character.

Faced with a new mutation in an organism, or a fundamental change in its living conditions, the biologist is frequently in no position whatever to predict its future prospects. He has to wait and see. For instance, the hairy mammoth seems to have been an admirable animal, intelligent and well-accoutered. Now that it is extinct, we try to understand why it failed. I doubt that any biologist thinks he could have predicted that failure. Fitness and survival are by nature estimates of past performance.

Finally in a large population, divided and subdivided into partially isolated local races of small size, there is a continually shifting differentiation among the latter (intensified by local differences in selection but occurring under uniform and static conditions) which inevitably brings about an indefinitely continuing, irreversible, adaptive, and much more rapid evolution of the species. Complete isolation in this case, and more slowly in the preceding, originates new species differing for the most part in nonadaptive parallel orthogenetic lines, in accordance with the conditions. It is suggested, in conclusion, that the differing statistical situations to be expected among natural species are adequate to account for the different sorts of evolutionary processes which have been described, and that, in particular, conditions in nature are often such as to bring about the state of poise among opposing tendencies on which an indefinitely continuing evolutionary process depends.

For nature by the same cause, provided it remain in the same condition, always produces the same effect, so that either coming-to-be or passing-away will always result.

For terrestrial vertebrates, the climate in the usual meteorological sense of the term would appear to be a reasonable approximation of the conditions of temperature, humidity, radiation, and air movement in which terrestrial vertebrates live. But, in fact, it would be difficult to find any other lay assumption about ecology and natural history which has less general validity. … Most vertebrates are much smaller than man and his domestic animals, and the universe of these small creatures is one of cracks and crevices, holes in logs, dense underbrush, tunnels, and nests—a world where distances are measured in yards rather than miles and where the difference between sunshine and shadow may be the difference between life and death. Actually, climate in the usual sense of the term is little more than a crude index to the physical conditions in which most terrestrial animals live.

For the evolution of science by societies the main requisite is the perfect freedom of communication between each member and anyone of the others who may act as a reagent.
The gaseous condition is exemplified in the soiree, where the members rush about confusedly, and the only communication is during a collision, which in some instances may be prolonged by button-holing.
The opposite condition, the crystalline, is shown in the lecture, where the members sit in rows, while science flows in an uninterrupted stream from a source which we take as the origin. This is radiation of science. Conduction takes place along the series of members seated round a dinner table, and fixed there for several hours, with flowers in the middle to prevent any cross currents.
The condition most favourable to life is an intermediate plastic or colloidal condition, where the order of business is (1) Greetings and confused talk; (2) A short communication from one who has something to say and to show; (3) Remarks on the communication addressed to the Chair, introducing matters irrelevant to the communication but interesting to the members; (4) This lets each member see who is interested in his special hobby, and who is likely to help him; and leads to (5) Confused conversation and examination of objects on the table.
I have not indicated how this programme is to be combined with eating.

For the mind is so intimately dependent upon the condition and relation of the organs of the body, that if any means can ever be found to render men wiser and more ingenious than hitherto, I believe that it is in medicine they must be sought for. It is true that the science of medicine, as it now exists, contains few things whose utility is very remarkable.

For the past 10 years I have had the interesting experience of observing the development of Parkinson's syndrome on myself. As a matter of fact, this condition does not come under my special medical interests or I would have had it solved long ago. … The condition has its compensations: one is not yanked from interesting work to go to the jungles of Burma ... one avoids all kinds of deadly committee meetings, etc.

For thousands of years men have striven and suffered and begotten and woman have brought forth in pain. A hundred years ago, perhaps, another man sat on this spot; like you he gazed with awe and yearning in his heart at the dying light on the glaciers. Like you he was begotten of man and born of woman. He felt pain and brief joy as you do. Was he someone else? Was it not you yourself? What is this Self of yours? What was the necessary condition for making the thing conceived this time into you, just you and not someone else?

Freudian psychoanalytical theory is a mythology that answers pretty well to Levi-Strauss's descriptions. It brings some kind of order into incoherence; it, too, hangs together, makes sense, leaves no loose ends, and is never (but never) at a loss for explanation. In a state of bewilderment it may therefore bring comfort and relief … give its subject a new and deeper understanding of his own condition and of the nature of his relationship to his fellow men. A mythical structure will be built up around him which makes sense and is believable-in, regardless of whether or not it is true.

Gauss was not the son of a mathematician; Handel’s father was a surgeon, of whose musical powers nothing is known; Titian was the son and also the nephew of a lawyer, while he and his brother, Francesco Vecellio, were the first painters in a family which produced a succession of seven other artists with diminishing talents. These facts do not, however, prove that the condition of the nerve-tracts and centres of the brain, which determine the specific talent, appeared for the first time in these men: the appropriate condition surely existed previously in their parents, although it did not achieve expression. They prove, as it seems to me, that a high degree of endowment in a special direction, which we call talent, cannot have arisen from the experience of previous generations, that is, by the exercise of the brain in the same specific direction.

Generality of points of view and of methods, precision and elegance in presentation, have become, since Lagrange, the common property of all who would lay claim to the rank of scientific mathematicians. And, even if this generality leads at times to abstruseness at the expense of intuition and applicability, so that general theorems are formulated which fail to apply to a single special case, if furthermore precision at times degenerates into a studied brevity which makes it more difficult to read an article than it was to write it; if, finally, elegance of form has well-nigh become in our day the criterion of the worth or worthlessness of a proposition,—yet are these conditions of the highest importance to a wholesome development, in that they keep the scientific material within the limits which are necessary both intrinsically and extrinsically if mathematics is not to spend itself in trivialities or smother in profusion.

Geology got into the hands of the theoreticians who were conditioned by the social and political history of their day more than by observations in the field. … We have allowed ourselves to be brainwashed into avoiding any interpretation of the past that involves extreme and what might be termed “catastrophic” processes. However, it seems to me that the stratigraphical record is full of examples of processes that are far from “normal” in the usual sense of the word. In particular we must conclude that sedimentation in the past has often been very rapid indeed and very spasmodic. This may be called the “Phenomenon of the Catastrophic Nature of the Stratigraphic Record.”

Germs of a theory, though in their present condition they are vague and formless … may be said to resemble stones in the quarry, rough and unhewn, but which may some time become corner-stones, columns, and entablatures in the future edifice.

GNU, n. An animal of South Africa, which in its domesticated state resembles a horse, a buffalo and a stag. In its wild condition it is something like a thunderbolt, an earthquake and a cyclone.

Groves hated the weather, and the weathermen; they represented chaos and the messengers of chaos. Weather violated boundaries, ignored walls and gates, failed to adhere to deadlines, disobeyed orders. Weather caused delays. The weather forecasters had opposed the [atomic bomb] test date for months—it was set within a window of unfavorable conditions: thunderstorms, rain, high winds, inversion layers. Groves had overridden them. … Groves saw it as a matter of insubordination when the weather forecasters refused to forecast good weather for the test.

Harvard Law: Under the most rigorously controlled conditions of pressure, temperature, humidity, and other variables, the organism will do as it damn well pleases.

He that could teach mathematics well, would not be a bad teacher in any of [physics, chemistry, biology or psychology] unless by the accident of total inaptitude for experimental illustration; while the mere experimentalist is likely to fall into the error of missing the essential condition of science as reasoned truth; not to speak of the danger of making the instruction an affair of sensation, glitter, or pyrotechnic show.

He will manage the cure best who has foreseen what is to happen from the present state of matters.

Hitherto the conception of chemical transmission at nerve endings and neuronal synapses, originating in Loewi’s discovery, and with the extension that the work of my colleagues has been able to give to it, can claim one practical result, in the specific, though alas only short, alleviation of the condition of myasthenia gravis, by eserine and its synthetic analogues.

Hitler is living—or shall I say sitting?—on the empty stomach of Germany. As soon as economic conditions improve, Hitler will sink into oblivion. He dramatizes impossible extremes in an amateurish manner.

How greatly would the heroes and statesmen of antiquity have despised the labours of that man who devoted his life to investigate the properties of the magnet! Little could they anticipate that this humble mineral was destined to change the very form and condition of human society in every quarter of the globe.

However, if we consider that all the characteristics which have been cited are only differences in degree of structure, may we not suppose that this special condition of organization of man has been gradually acquired at the close of a long period of time, with the aid of circumstances which have proved favorable? What a subject for reflection for those who have the courage to enter into it!

Hubble's observations suggested that there was a time, called the big bang, when the universe was infinitesimally small and infinitely dense. Under such conditions all the laws of science, and therefore all ability to predict the future, would break down. If there were events earlier than this time, then they could not affect what happens at the present time. Their existence can be ignored because it would have no observational consequences. One may say that time had a beginning at the big bang, in the sense that earlier times simply would not be defined. It should be emphasized that this beginning in time is very different from those that had been considered previously. In an unchanging universe a beginning in time is something that has to be imposed by some being outside the universe; there is no physical necessity for a beginning. One can imagine that God created the universe at literally any time in the past. On the other hand, if the universe is expanding, there may be physical reasons why there had to be a beginning. One could still imagine that God created the universe at the instant of the big bang, or even afterwards in just such a way as to make it look as though there had been a big bang, but it would be meaningless to suppose that it was created before the big bang. An expanding universe does not preclude a creator, but it does place limits on when he might have carried out his job!

I believe that the medical treatment of the various abnormal conditions arising in infants is in the future to be largely dietetic rather than by means of drugs.

I believe that, as men occupied with the study and treatment of disease, we cannot have too strong a conviction that the problems presented to us are physical problems, which perhaps we may never solve, but still admitting of solution only in one way, namely, by regarding them as part of an unbroken series, running up from the lowest elementary conditions of matter to the highest composition of organic structure.

I can’t work well under the conditions at Bell Labs. Walter [Brattain] and I are looking at a few questions relating to point-contact transistors, but [William] Shockley keeps all the interesting problems for himself.

I have attempted to form a judgment as to the conditions for evolution based on the statistical consequences of Mendelian heredity. The most general conclusion is that evolution depends on a certain balance among its factors. There must be a gene mutation, but an excessive rate gives an array of freaks, not evolution; there must be selection, but too severe a process destroys the field of variability, and thus the basis for further advance; prevalence of local inbreeding within a species has extremely important evolutionary consequences, but too close inbreeding leads merely to extinction. A certain amount of crossbreeding is favorable but not too much. In this dependence on balance the species is like a living organism. At all levels of organization life depends on the maintenance of a certain balance among its factors.

I have presented principles of philosophy that are not, however, philosophical but strictly mathematical—that is, those on which the study of philosophy can be based. These principles are the laws and conditions of motions and of forces, which especially relate to philosophy.

I have taken your advice, and the names used are anode cathode anions cations and ions; the last I shall have but little occasion for. I had some hot objections made to them here and found myself very much in the condition of the man with his son and ass who tried to please every body; but when I held up the shield of your authority, it was wonderful to observe how the tone of objection melted away.

I hope you enjoy the absence of pupils … the total oblivion of them for definite intervals is a necessary condition for doing them justice at the proper time.

I should object to any experimentation which can justly be called painful, for the purpose of elementary instruction ... [but I regret] a condition of the law which permits a boy to troll for pike, or set lines with live frog bait, for idle amusement; and, at the same time, lays the teacher of that boy open to the penalty of fine and imprisonment, if he uses the same animal for the purpose of exhibiting one of the most beautiful and instructive of physiological spectacles, the circulation in the web of the foot. ... [Maybe the frog is] inconvenienced by being wrapped up in a wet rag, and having his toes tied out ... But you must not inflict the least pain on a vertebrated animal for scientific purposes (though you may do a good deal in that way for gain or for sport) without due licence of the Secretary of State for the Home Department, granted under the authority of the Vivisection Act.
... [Yet, in] 1877, two persons may be charged with cruelty to animals. One has impaled a frog, and suffered the creature to writhe about in that condition for hours; the other has pained the animal no more than one of us would be pained by tying strings round his fingers, and keeping him in the position of a hydropathic patient. The first offender says, 'I did it because I find fishing very amusing,' and the magistrate bids him depart in peace; nay, probably wishes him good sport. The second pleads, 'I wanted to impress a scientific truth, with a distinctness attainable in no other way, on the minds of my scholars,' and the magistrate fines him five pounds.
I cannot but think that this is an anomalous and not wholly creditable state of things.

I sometimes hear preachers speak of the sad condition of men who live without God in the world, but a scientist who lives without God in the world seems to me worse off than ordinary men.

I tell [medical students] that they are the luckiest persons on earth to be in medical school, and to forget all this worry about H.M.O.’s and keep your eye on helping the patient. It’s the best time ever to be a doctor because you can heal and treat conditions that were untreatable even a couple of years ago.

I think it would be a very rash presumption to think that nowhere else in the cosmos has nature repeated the strange experiment which she has performed on earth—that the whole purpose of creation has been staked on this one planet alone. It is probable that dotted through the cosmos there are other suns which provide the energy for life to attendant planets. It is apparent, however, that planets with just the right conditions of temperature, oxygen, water and atmosphere necessary for life are found rarely.
But uncommon as a habitable planet may be, non-terrestrial life exists, has existed and will continue to exist. In the absence of information, we can only surmise that the chance that it surpasses our own is as good as that it falls below our level.

I think that space flight is a condition of Nature that comes into effect when an intelligent species reaches the saturation point of its planetary habitat combined with a certain level of technological ability... I think it is a built-in gene-directed drive for the spreading of the species and its continuation.

I think the next [21st] century will be the century of complexity. We have already discovered the basic laws that govern matter and understand all the normal situations. We don’t know how the laws fit together, and what happens under extreme conditions. But I expect we will find a complete unified theory sometime this century. The is no limit to the complexity that we can build using those basic laws.
[Answer to question: Some say that while the twentieth century was the century of physics, we are now entering the century of biology. What do you think of this?]

I will insist particularly upon the following fact, which seems to me quite important and beyond the phenomena which one could expect to observe: The same [double sulfate of uranium and potassium] crystalline crusts, arranged the same way [as reported to the French academy on 24 Feb 1896] with respect to the photographic plates, in the same conditions and through the same screens, but sheltered from the excitation of incident rays and kept in darkness, still produce the same photographic images … [when kept from 26 Feb 1896] in the darkness of a bureau drawer. … I developed the photographic plates on the 1st of March, expecting to find the images very weak. Instead the silhouettes appeared with great intensity.
It is important to observe that it appears this phenomenon must not be attributed to the luminous radiation emitted by phosphorescence … One hypothesis which presents itself to the mind naturally enough would be to suppose that these rays, whose effects have a great similarity to the effects produced by the rays studied by M. Lenard and M. Röntgen, are invisible rays …
[Having eliminated phosphorescence as a cause, he has further revealed the effect of the as yet unknown radioactivity.]

If a mathematician of the past, an Archimedes or even a Descartes, could view the field of geometry in its present condition, the first feature to impress him would be its lack of concreteness. There are whole classes of geometric theories which proceed not only without models and diagrams, but without the slightest (apparent) use of spatial intuition. In the main this is due, to the power of the analytic instruments of investigations as compared with the purely geometric.

If a single cell, under appropriate conditions, becomes a man in the space of a few years, there can surely be no difficulty in understanding how, under appropriate conditions, a cell may, in the course of untold millions of years, give origin to the human race.

If any spiritualistic medium can do stunts, there is no more need for special conditions than there is for a chemist to turn down lights, start operations with a hymn, and ask whether there's any chemical present that has affinity with something named Hydrogen.

If experiments are performed thousands of times at all seasons and in every place without once producing the effects mentioned by your philosophers, poets, and historians, this will mean nothing and we must believe their words rather our own eyes? But what if I find for you a state of the air that has all the conditions you say are required, and still the egg is not cooked nor the lead ball destroyed? Alas! I should be wasting my efforts... for all too prudently you have secured your position by saying that 'there is needed for this effect violent motion, a great quantity of exhalations, a highly attenuated material and whatever else conduces to it.' This 'whatever else' is what beats me, and gives you a blessed harbor, a sanctuary completely secure.