As a scientist and geneticist I started to feel that science would probably soon reach the point where its interference into the life processes would be counterproductive if a properly designed governing policy was not implemented. A heavily overcrowded planet, ninety-five percent urbanized with nuclear energy as the main source of energy and with all aspects of life highly computerized, is not too pleasant a place for human life. The life of any individual soon will be predictable from birth to death. Medicine, able to cure almost everything, will make the load of accumulated defects too heavy in the next two or three centuries. The artificial prolongation of life, which looked like a very bright idea when I started research in aging about twenty-five years ago, has now lost its attractiveness for me. This is because I now know that the aging process is so multiform and complex that the real technology and chemistry of its prevention by artificial interference must be too complex and expensive. It would be the privilege of a few, not the method for the majority. I also was deeply concerned about the fact that most research is now either directly or indirectly related to military projects and objectives for power.

Engineering is the practice of safe and economic application of the scientific laws governing the forces and materials of nature by means of organization, design and construction, for the general benefit of mankind.

Every science has for its basis a system of principles as fixed and unalterable as those by which the universe is regulated and governed. Man cannot make principles; he can only discover them.

I fully agree with all that you say on the advantages of H. Spencer's excellent expression of 'the survival of the fittest.' This, however, had not occurred to me till reading your letter. It is, however, a great objection to this term that it cannot be used as a substantive governing a verb; and that this is a real objection I infer from H. Spencer continually using the words, natural selection.

I suppose that I tend to be optimistic about the future of physics. And nothing makes me more optimistic than the discovery of broken symmetries. In the seventh book of the Republic, Plato describes prisoners who are chained in a cave and can see only shadows that things outside cast on the cave wall. When released from the cave at first their eyes hurt, and for a while they think that the shadows they saw in the cave are more real than the objects they now see. But eventually their vision clears, and they can understand how beautiful the real world is. We are in such a cave, imprisoned by the limitations on the sorts of experiments we can do. In particular, we can study matter only at relatively low temperatures, where symmetries are likely to be spontaneously broken, so that nature does not appear very simple or unified. We have not been able to get out of this cave, but by looking long and hard at the shadows on the cave wall, we can at least make out the shapes of symmetries, which though broken, are exact principles governing all phenomena, expressions of the beauty of the world outside.

I think the next [21st] century will be the century of complexity. We have already discovered the basic laws that govern matter and understand all the normal situations. We don’t know how the laws fit together, and what happens under extreme conditions. But I expect we will find a complete unified theory sometime this century. The is no limit to the complexity that we can build using those basic laws.
[Answer to question: Some say that while the twentieth century was the century of physics, we are now entering the century of biology. What do you think of this?]

If and when all the laws governing physical phenomena are finally discovered, and all the empirical constants occurring in these laws are finally expressed through the four independent basic constants, we will be able to say that physical science has reached its end, that no excitement is left in further explorations, and that all that remains to a physicist is either tedious work on minor details or the self-educational study and adoration of the magnificence of the completed system. At that stage physical science will enter from the epoch of Columbus and Magellan into the epoch of the National Geographic Magazine!

My original decision to devote myself to science was a direct result of the discovery which has never ceased to fill me with enthusiasm since my early youth—the comprehension of the far from obvious fact that the laws of human reasoning coincide with the laws governing the sequences of the impressions we receive from the world about us; that, therefore, pure reasoning can enable man to gain an insight into the mechanism of the latter. In this connection, it is of paramount importance that the outside world is something independent from man, something absolute, and the quest for the laws which apply to this absolute appeared to me as the most sublime scientific pursuit in life.

Physical science is thus approaching the stage when it will be complete, and therefore uninteresting. Given the laws governing the motions of electrons and protons, the rest is merely geography—a collection of particular facts.

Science, in its ultimate ideal, consists of a set of propositions arranged in a hierarchy, the lowest level of the hierarchy being concerned with particular facts, and the highest with some general law, governing everything in the universe. The various levels in the hierarchy have a two-fold logical connection, travelling one up, one down; the upward connection proceeds by induction, the downward by deduction.

Scientific method, although in its more refined forms it may seem complicated, is in essence remarkably simply. It consists in observing such facts as will enable the observer to discover general laws governing facts of the kind in question. The two stages, first of observation, and second of inference to a law, are both essential, and each is susceptible of almost indefinite refinement. (1931)

The animal kingdom exhibits a series of mental developments which may be regarded as antecedents to the mental development of man, for the mental life of animals shows itself to be throughout, in its elements and in the general laws governing the combination of the elements, the same as the mental life of man.

The focal points of our different reflections have been called “science”’ or “art” according to the nature of their “formal” objects, to use the language of logic. If the object leads to action, we give the name of “art” to the compendium of rules governing its use and to their technical order. If the object is merely contemplated under different aspects, the compendium and technical order of the observations concerning this object are called “science.” Thus metaphysics is a science and ethics is an art. The same is true of theology and pyrotechnics.

The future science of government should be called “la cybernétique”.

The game of chess has always fascinated mathematicians, and there is reason to suppose that the possession of great powers of playing that game is in many features very much like the possession of great mathematical ability. There are the different pieces to learn, the pawns, the knights, the bishops, the castles, and the queen and king. The board possesses certain possible combinations of squares, as in rows, diagonals, etc. The pieces are subject to certain rules by which their motions are governed, and there are other rules governing the players. … One has only to increase the number of pieces, to enlarge the field of the board, and to produce new rules which are to govern either the pieces or the player, to have a pretty good idea of what mathematics consists.

The prediction of nuclear winter is drawn not, of course, from any direct experience with the consequences of global nuclear war, but rather from an investigation of the governing physics. (The problem does not lend itself to full experimental verification—at least not more than once.)[co-author with American atmospheric chemist Richard P. Turco (1943- )]

The universe is governed by science. But science tells us that we can’t solve the equations, directly in the abstract. We need to use the effective theory of Darwinian natural selection of those societies most likely to survive. We assign them higher value.
[Answer to question: What is the value in knowing “Why are we here?”]

Too early and perverse sexual satisfaction injures not merely the mind, but also the body; inasmuch as it induces neuroses of the sexual apparatus (irritable weakness of the centres governing erection and ejaculation; defective pleasurable feeling in coitus), while, at the same time, it maintains the imagination and libido in continuous excitement.

We have simply arrived too late in the history of the universe to see this primordial simplicity easily ... But although the symmetries are hidden from us, we can sense that they are latent in nature, governing everything about us. That's the most exciting idea I know: that nature is much simpler than it looks. Nothing makes me more hopeful that our generation of human beings may actually hold the key to the universe in our hands—that perhaps in our lifetimes we may be able to tell why all of what we see in this immense universe of galaxies and particles is logically inevitable.

Whoever would not remain in complete ignorance of the resources which cause him to act; whoever would seize, at a single philosophical glance, the nature of man and animals, and their relations to external objects; whoever would establish, on the intellectual and moral functions, a solid doctrine of mental diseases, of the general and governing influence of the brain in the states of health and disease, should know, that it is indispensable, that the study of the organization of the brain should march side by side with that of its functions.