[The surplus of basic knowledge of the atomic nucleus was] largely used up [during the war with the atomic bomb as the dividend.] We must, without further delay restore this surplus in preparation for the important peacetime job for the nucleus - power production. ... Many of the proposed applications of atomic power - even for interplanetary rockets - seem to be within the realm of possibility provided the economic factor is ruled out completely, and the doubtful physical and chemical factors are weighted heavily on the optimistic side. ... The development of economic atomic power is not a simple extrapolation of knowledge gained during the bomb work. It is a new and difficult project to reach a satisfactory answer. Needless to say, it is vital that the atomic policy legislation now being considered by the congress recognizes the essential nature of this peacetime job, and that it not only permits but encourages the cooperative research-engineering effort of industrial, government and university laboratories for the task. ... We must learn how to generate the still higher energy particles of the cosmic rays - up to 1,000,000,000 volts, for they will unlock new domains in the nucleus.

Question: What is the reason that the hammers which strike the strings of a pianoforte are made not to strike the middle of the strings? Why are the bass strings loaded with coils of wire?
Answer: Because the tint of the clang would be bad. Because to jockey them heavily.

Accountants and second-rate business school jargon are in the ascendant. Costs, which rise rapidly, and are easily ascertained and comprehensible, now weigh more heavily in the scales than the unquantifiable and unpredictable values and future material progress. Perhaps science will only regain its lost primacy as peoples and government begin to recognize that sound scientific work is the only secure basis for the construction of policies to ensure the survival of Mankind without irreversible damage to Planet Earth.

As a scientist and geneticist I started to feel that science would probably soon reach the point where its interference into the life processes would be counterproductive if a properly designed governing policy was not implemented. A heavily overcrowded planet, ninety-five percent urbanized with nuclear energy as the main source of energy and with all aspects of life highly computerized, is not too pleasant a place for human life. The life of any individual soon will be predictable from birth to death. Medicine, able to cure almost everything, will make the load of accumulated defects too heavy in the next two or three centuries. The artificial prolongation of life, which looked like a very bright idea when I started research in aging about twenty-five years ago, has now lost its attractiveness for me. This is because I now know that the aging process is so multiform and complex that the real technology and chemistry of its prevention by artificial interference must be too complex and expensive. It would be the privilege of a few, not the method for the majority. I also was deeply concerned about the fact that most research is now either directly or indirectly related to military projects and objectives for power.

Biological disciplines tend to guide research into certain channels. One consequence is that disciplines are apt to become parochial, or at least to develop blind spots, for example, to treat some questions as “interesting” and to dismiss others as “uninteresting.” As a consequence, readily accessible but unworked areas of genuine biological interest often lie in plain sight but untouched within one discipline while being heavily worked in another. For example, historically insect physiologists have paid relatively little attention to the behavioral and physiological control of body temperature and its energetic and ecological consequences, whereas many students of the comparative physiology of terrestrial vertebrates have been virtually fixated on that topic. For the past 10 years, several of my students and I have exploited this situation by taking the standard questions and techniques from comparative vertebrate physiology and applying them to insects. It is surprising that this pattern of innovation is not more deliberately employed.

I think at the moment we did not even want to break the seal [on the inner chamber of the tomb of Tutankhamen], for a feeling of intrusion had descended heavily upon us... We felt that we were in the presence of the dead King and must do him reverence, and in imagination could see the doors of the successive shrines open one.

It goes so heavily with my disposition that this goodly frame, the earth, seems to me a sterile promontory. This most excellent canopy the air, look you, this brave o'erhanging, this majestic roof fretted with golden fire—why, it appears no other thing to me than a foul and pestilent congregation of vapours. What a piece of work is a man. How noble in reason, how infinite in faculty, in form and moving, how express and admirable, in action, how like an angel! in apprehension, how like a god—the beauty of the world, the paragon of animals! And yet to me, what is this quintessence of dust? Man delights not me—no, nor woman neither, though by your smiling you seem to say so.

The edge of the sea is a strange and beautiful place. All through the long history of Earth it has been an area of unrest where waves have broken heavily against the land, where the tides have pressed forward over the continents, receded, and then returned. For no two successive days is the shore line precisely the same. Not only do the tides advance and retreat in their eternal rhythms, but the level of the sea itself is never at rest. It rises or falls as the glaciers melt or grow, as the floor of the deep ocean basins shifts under its increasing load of sediments, or as the Earth’s crust along the continental margins warps up or down in adjustment to strain and tension. Today a little more land may belong to the sea, tomorrow a little less. Always the edge of the sea remains an elusive and indefinable boundary.

The information reported in this section [about the two different forms, A and B, of DNA] was very kindly reported to us prior to its publication by Drs Wilkins and Franklin. We are most heavily indebted in this respect to the Kings College Group, and we wish to point out that without this data the formation of the picture would have been most unlikely, if not impossible.
[Co-author with Francis Crick]

There is only one proved method of assisting the advancement of pure science—that of picking men of genius, backing them heavily, and leaving them to direct themselves.

To pray without faith is to make a small fire while it is raining heavily.

We urgently need [the landmark National Ocean Policy] initiative, as we use our oceans heavily: Cargo ships crisscross the sea, carrying goods between continents. Commercial and recreational fishing boats chase fish just offshore. Cruise ships cruise. Oil and gas drilling continues, but hopefully we will add renewable energy projects as well. Without planning, however, these various industrial activities amount to what we call “ocean sprawl,” steamrolling the resources we rely upon for our livelihoods, food, fun, and even the air we breathe. While humankind relies on many of these industries, we also need to keep the natural riches that support them healthy and thriving. As an explorer, I know firsthand there are many places in the ocean so full of life that they should be protected.

When you look at the companies that have really won customers over in technology—say, Apple and Google—you find that they spend billions of dollars on R&D [research and development] each year, often spending that much on a product before they ever make a dime back in profits. Unfortunately, in the environment, I don’t see as much willingness to invest heavily in R&D as I do in consumer technology. And that’s a pity.

While up to this time contrary sexual instinct has had but an anthropological, clinical, and forensic interest for science, now, as a result of the latest investigations, there is some thought of therapy in this incurable condition, which so heavily burdens its victims, socially, morally, and mentally. A preparatory step for the application of therapeutic measures is the exact differentiation of the acquired from the congenital cases; and among the latter again, the assignment of the concrete case to its proper position in the categories that have been established empirically.