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Who said: “Nature does nothing in vain when less will serve; for Nature is pleased with simplicity and affects not the pomp of superfluous causes.”
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Home > Category Index for Science Quotations > Category Index V > Category: Virus

Virus Quotes (23 quotes)

...on opening the incubator I experienced one of those rare moments of intense emotion which reward the research worker for all his pains: at first glance I saw that the broth culture, which the night before had been very turbid was perfectly clear: all the bacteria had vanished... as for my agar spread it was devoid of all growth and what caused my emotion was that in a flash I understood: what causes my spots was in fact an invisible microbe, a filterable virus, but a virus parasitic on bacteria. Another thought came to me also, If this is true, the same thing will have probably occurred in the sick man. In his intestine, as in my test-tube, the dysentery bacilli will have dissolved away under the action of their parasite. He should now be cured.
In Allan Chase, Magic Shots: A Human and Scientific Account of the Long and Continuing Struggle to Eradicated Infectious Diseases by Vaccination (1982), 249-250. Also in Allan J. Tobin and Jennie Dusheck, Asking About Life (2005), 206.
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A lot of people ask, “Do you think humans are parasites?” It’s an interesting idea and one worth thinking about. People casually refer to humanity as a virus spreading across the earth. In fact, we do look like some strange kind of bio-film spreading across the landscape. A good metaphor? If the biosphere is our host, we do use it up for our own benefit. We do manipulate it. We alter the flows and fluxes of elements like carbon and nitrogen to benefit ourselves—often at the expense of the biosphere as a whole. If you look at how coral reefs or tropical forests are faring these days, you’ll notice that our host is not doing that well right now. Parasites are very sophisticated; parasites are highly evolved; parasites are very successful, as reflected in their diversity. Humans are not very good parasites. Successful parasites do a very good job of balancing—using up their hosts and keeping them alive. It’s all a question of tuning the adaptation to your particular host. In our case, we have only one host, so we have to be particularly careful.
Talk at Columbia University, 'The Power of Parasites'.
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A strong feeling of adventure is animating those who are working on bacterial viruses, a feeling that they have a small part in the great drive towards a fundamental problem in biology.
From 'Experiments with Bacterial Viruses (Bacteriophages)', Harvey Lecture (1946), 41, 187. As cited in Robert Olby, The Path of the Double Helix: The Discovery of DNA (1974, 1994), 238.
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All living things need their instruction manual (even nonliving things like viruses) and that is all they need, carried in one very small suitcase.
In The Center of Life: A Natural History of the Cell (1977, 1978), 8.
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Almost daily we shudder as prophets of doom announce the impending end of civilization and universe. We are being asphyxiated, they say, by the smoke of the industry; we are suffocating in the ever growing mountain of rubbish. Every new project depicts its measureable effects and is denounced by protesters screaming about catastrophe, the upsetting of the land, the assault on nature. If we accepted this new mythology we would have to stop pushing roads through the forest, harnessing rivers to produce the electricity, breaking grounds to extract metals, enriching the soil with chemicals, killing insects, combating viruses … But progress—basically, an effort to organise a corner of land and make it more favourable for human life—cannot be baited. Without the science of pomiculture, for example, trees will bear fruits that are small, bitter, hard, indigestible, and sour. Progress is desirable.
Uncredited. In Lachman Mehta, Stolen Treasure (2012), 117.
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But however secure and well-regulated civilized life may become, bacteria, Protozoa, viruses, infected fleas, lice, ticks, mosquitoes, and bedbugs will always lurk in the shadows ready to pounce when neglect, poverty, famine, or war lets down the defenses.
Rats, Lice and History (1934), 13-4.
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By teaching us how to cultivate each ferment in its purity—in other words, by teaching us how to rear the individual organism apart from all others,—Pasteur has enabled us to avoid all these errors. And where this isolation of a particular organism has been duly effected it grows and multiplies indefinitely, but no change of it into another organism is ever observed. In Pasteur’s researches the Bacterium remained a Bacterium, the Vibrio a Vibrio, the Penicillium a Penicillium, and the Torula a Torula. Sow any of these in a state of purity in an appropriate liquid; you get it, and it alone, in the subsequent crop. In like manner, sow smallpox in the human body, your crop is smallpox. Sow there scarlatina, and your crop is scarlatina. Sow typhoid virus, your crop is typhoid—cholera, your crop is cholera. The disease bears as constant a relation to its contagium as the microscopic organisms just enumerated do to their germs, or indeed as a thistle does to its seed.
In 'Fermentation, and its Bearings on Surgery and Medicine', Essays on the Floating­Matter of the Air in Relation to Putrefaction and Infection (1881), 264.
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For the philosopher, order is the entirety of repetitions manifested, in the form of types or of laws, by perceived objects. Order is an intelligible relation. For the biologist, order is a sequence in space and time. However, according to Plato, all things arise out of their opposites. Order was born of the original disorder, and the long evolution responsible for the present biological order necessarily had to engender disorder.
An organism is a molecular society, and biological order is a kind of social order. Social order is opposed to revolution, which is an abrupt change of order, and to anarchy, which is the absence of order.
I am presenting here today both revolution and anarchy, for which I am fortunately not the only one responsible. However, anarchy cannot survive and prosper except in an ordered society, and revolution becomes sooner or later the new order. Viruses have not failed to follow the general law. They are strict parasites which, born of disorder, have created a very remarkable new order to ensure their own perpetuation.
'Interaction Among Virus, Cell, and Organism', Nobel Lecture (11 Dec 1965). In Nobel Lectures: Physiology or Medicine 1963-1970 (1972), 174.
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He saw virus particles shaped like snakes, in negative images. They were white cobras tangled among themselves, like the hair of Medusa. They were the face of nature herself, the obscene goddess revealed naked. This life form thing was breathtakingly beautiful. As he stared at it, he found himself being pulled out of the human world into a world where moral boundaries blur and finally dissolve completely. He was lost in wonder and admiration, even though he knew that he was the prey.
The Hot Zone
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I would picture myself as a virus, or as a cancer cell, for example, and try to sense what it would be like to be either. I would also imagine myself as the immune system, and I would try to reconstruct what I would do as an immune system engaged in combating a virus or cancer cell. When I had played through a series of such scenarios on a particular problem and had acquired new insights, I would design laboratory experiments accordingly… Based upon the results of the experiment, I would then know what question to ask next… When I observed phenomena in the laboratory that I did not understand, I would also ask questions as if interrogating myself: “Why would I do that if I were a virus or a cancer cell, or the immune system?” Before long, this internal dialogue became second nature to me; I found that my mind worked this way all the time.
In Anatomy of Reality: Merging of Intuition and Reason (1983), 7, footnote b, as quoted and cited in Roger Frantz, Two Minds: Intuition and Analysis in the History of Economic Thought (2006), 7.
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If the structure that serves as a template (the gene or virus molecule) consists of, say, two parts, which are themselves complementary In structure, then each of these parts can serve as the mould for the production of a replica of the other part, and the complex of two complementary parts thus can serve as the mould for the production of duplicates of itself.
Molecular Architecture and the Processses of Life (1948), 10.
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Influenza is something unique. It behaves epidemiologically in a way different from that of any other known infection.
In W.I.B . Beveridge, Influenza: The Last Great Plague (1977), ix.
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My ambition was to bring to bear on medicine a chemical approach. I did that by chemical manipulation of viruses and chemical ways of thinking in biomedical research.
From interview (1980) quoted in New York Times (24 Jun 1995), 9.
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One can ask: “If I crystallize a virus to obtain a crystal consisting of the molecules that make up the virus, are those molecules lifeless or not?” … The properties of living organisms are those of aggregates of molecules. It’s very difficult to draw a line between molecules that are lifeless and molecules that are not lifeless.
From interview with Neil A. Campbell, in 'Crossing the Boundaries of Science', BioScience (Dec 1986), 36, No. 11, 738.
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Parasites are not only incredibly diverse; they are also incredibly successful. There are parasitic stretches of DNA in your own genes, some of which are called retrotransposons. Many of the parasitic stretches were originally viruses that entered our DNA. Most of them don't do us any harm. They just copy and insert themselves in other parts of our DNA, basically replicating themselves. Sometimes they hop into other species and replicate themselves in a new host. According to one estimate, roughly one-third to one-half of all human DNA is basically parasitic.
Talk at Columbia University, 'The Power of Parasites.'
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Primates stand at a turning point in the course of evolution. Primates are to the biologist what viruses are to the biochemist. They can be analysed and partly understood according to the rules of a simpler discipline, but they also present another level of complexity: viruses are living chemicals, and primates are animals who love and hate and think.
'The Evolution of Primate Behavior: A survey of the primate order traces the progressive development of intelligence as a way of life', American Scientist (1985), 73, 288.
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Suppose [an] imaginary physicist, the student of Niels Bohr, is shown an experiment in which a virus particle enters a bacterial cell and 20 minutes later the bacterial cell is lysed and 100 virus particles are liberated. He will say: “How come, one particle has become 100 particles of the same kind in 20 minutes? That is very interesting. Let us find out how it happens! How does the particle get in to the bacterium? How does it multiply? Does it multiply like a bacterium, growing and dividing, or does it multiply by an entirely different mechanism ? Does it have to be inside the bacterium to do this multiplying, or can we squash the bacterium and have the multiplication go on as before? Is this multiplying a trick of organic chemistry which the organic chemists have not yet discovered ? Let us find out. This is so simple a phenomenon that the answers cannot be hard to find. In a few months we will know. All we have to do is to study how conditions will influence the multiplication. We will do a few experiments at different temperatures, in different media, with different viruses, and we will know. Perhaps we may have to break into the bacteria at intermediate stages between infection and lysis. Anyhow, the experiments only take a few hours each, so the whole problem can not take long to solve.”
[Eight years later] he has not got anywhere in solving the problem he set out to solve. But [he may say to you] “Well, I made a slight mistake. I could not do it in a few months. Perhaps it will take a few decades, and perhaps it will take the help of a few dozen other people. But listen to what I have found, perhaps you will be interested to join me.”
From 'Experiments with Bacterial Viruses (Bacteriophages)', Harvey Lecture (1946), 41, 161-162. As cited in Robert Olby, The Path of the Double Helix: The Discovery of DNA (1974, 1994), 237.
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The fact that, with respect to size, the viruses overlapped with the organisms of the biologist at one extreme and with the molecules of the chemist at the other extreme only served to heighten the mystery regarding the nature of viruses. Then too, it became obvious that a sharp line dividing living from non-living things could not be drawn and this fact served to add fuel for discussion of the age-old question of “What is life?”
Nobel Lecture (12 Dec 1946), 'The Isolation and Properties of Crystalline Tobacco Mosaic Virus', collected in Nobel Lectures in Chemistry (1999), 140.
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The nucleic acids, as constituents of living organisms, are comparable In importance to proteins. There is evidence that they are Involved In the processes of cell division and growth, that they participate In the transmission of hereditary characters, and that they are important constituents of viruses. An understanding of the molecular structure of the nucleic acids should be of value In the effort to understand the fundamental phenomena of life.
[Co-author with American chemist, B. Corey (1897-1971)]
'A Proposed Structure for the Nucleic Acids', Proceedings of the National Academy of Sciences (1953), 39, 84.
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These results demonstrate that there is a new polymerase inside the virions of RNA tumour viruses. It is not present in supernatents of normal cells but is present in virions of avian sarcoma and leukemia RNA tumour viruses. The polymerase seems to catalyse the incorporation of deoxyrinonucleotide triphosphates into DNA from an RNA template. Work is being performed to characterize further the reaction and the product. If the present results and Baltimore's results with Rauscher leukemia virus are upheld, they will constitute strong evidence that the DNA proviruses have a DNA genome when they are in virions. This result would have strong implications for theories of viral carcinogenesis and, possibly, for theories of information transfer in other biological systems. [Co-author with American virologist Satoshi Mizutani]
'RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus', Nature (1970), 226, 1213.
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We think of something that has four legs and wags its tail as being alive. We look at a rock and say it’s not living. Yet when we get down to the no man’s land of virus particles and replicating molecules, we are hard put to define what is living and what is non-living.
From interview, 'The Seeds of Life', in The Omni Interviews (1984), 4.
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When there are too many deer in the forest or too many cats in the barn, nature restores the balance by the introduction of a communicable disease or virus.
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[Physicists] feel that the field of bacterial viruses is a fine playground for serious children who ask ambitious questions.
From 'Experiments with Bacterial Viruses (Bacteriophages)', Harvey Lecture (1946), 41, 161. As cited in Robert Olby, The Path of the Double Helix: The Discovery of DNA (1974, 1994), 237.
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Carl Sagan Thumbnail In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time something like that happened in politics or religion. (1987) -- Carl Sagan
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