Interrogate Quotes (4 quotes)
I would picture myself as a virus, or as a cancer cell, for example, and try to sense what it would be like to be either. I would also imagine myself as the immune system, and I would try to reconstruct what I would do as an immune system engaged in combating a virus or cancer cell. When I had played through a series of such scenarios on a particular problem and had acquired new insights, I would design laboratory experiments accordingly… Based upon the results of the experiment, I would then know what question to ask next… When I observed phenomena in the laboratory that I did not understand, I would also ask questions as if interrogating myself: “Why would I do that if I were a virus or a cancer cell, or the immune system?” Before long, this internal dialogue became second nature to me; I found that my mind worked this way all the time.
Of our three principal instruments for interrogating Nature,—observation, experiment, and comparison,—the second plays in biology a quite subordinate part. But while, on the one hand, the extreme complication of causes involved in vital processes renders the application of experiment altogether precarious in its results, on the other hand, the endless variety of organic phenomena offers peculiar facilities for the successful employment of comparison and analogy.
Preconceived ideas are like searchlights which illumine the path of experimenter and serve him as a guide to interrogate nature. They become a danger only if he transforms them into fixed ideas – this is why I should like to see these profound words inscribed on the threshold of all the temples of science: “The greatest derangement of the mind is to believe in something because one wishes it to be so.”
This marvellous experimental method eliminates certain facts, brings forth others, interrogates nature, compels it to reply and stops only when the mind is fully satisfied. The charm of our studies, the enchantment of science, is that, everywhere and always, we can give the justification of our principles and the proof of our discoveries.