… however useful the words may have been in the past, they have now become handicaps to the further development of knowledge. Words like botany and zoology imply that plants and animals are quite different things. … But the differences rapidly become blurred when we start looking at the world through a microscope. … The similarities between plants and animals became more important than their differences with the discoveries that both were built up of cells, had sexual reproduction,… nutrition and respiration … and with the development of evolutionary theory.

... we ought to have saints' days to commemorate the great discoveries which have been made for all mankind, and perhaps for all time—or for whatever time may be left to us. Nature ... is a prodigal of pain. I should like to find a day when we can take a holiday, a day of jubilation when we can fête good Saint Anaesthesia and chaste and pure Saint Antiseptic. ... I should be bound to celebrate, among others, Saint Penicillin...

...I believe there exists, & I feel within me, an instinct for the truth, or knowledge or discovery, of something of the same nature as the instinct of virtue, & that our having such an instinct is reason enough for scientific researches without any practical results ever ensuing from them.

...neither is it possible to discover the more remote and deeper parts of any science, if you stand but upon the level of the same science, and ascend not to a higher science.

“Does one error disappear only to make room for another?” … [L]et us look at the science of astronomy. How grand and magnificent have been the discoveries in that field of knowledge. What victories over error have been achieved by the telescope. That instrument did … bring down and dispel vast clouds of error, both in respect of the sky and of our planet. It must be confessed, too, that it took something from the importance of our planet. The idea that all the hosts of heaven are mere appendages to this earth is no longer entertained by average men, and … [almost no men] now stand by the old theory for which the church proposed to murder Galileo. Men are compelled to admit that the Genesis by Moses is less trustworthy as to the time of creating the heavens and the earth than are the rocks and the stars.

“On doit etre etonné ([Abbé Raynal]says) que l'Amerique n’ait pas encore produit un bon poëte, un habile mathematicien, un homme de génie dans un seul art, ou une seule science.” …“America has not yet produced one good poet.” When we shall have existed as a people as long as the Greeks did before they produced a Homer, the Romans a Virgil, the French a Racine and Voltaire, the English a Shakespeare and Milton, should this reproach be still true, we will enquire from what unfriendly causes it has proceeded, that the other countries of Europe and quarters of the earth shall not have inscribed any name in the roll of poets. But neither has America produced “one able mathematician, one man of genius in a single art or a single science.” … In physics we have produced a [Benjamin] Franklin, than whom no one of the present age has made more important discoveries, nor has enriched philosophy with more, or more ingenious solutions of the phaenomena, of nature. … [The quadrant invented by Godfrey, an American also, and with the aid of which the European nations traverse the globe, is called Hadley’s quadrant.] … We have supposed Mr. [David] Rittenhouse second to no astronomer living: that in genius he must be the first, because he is self-taught. As an artist he has exhibited as great a proof of mechanical genius as the world has ever produced. … We therefore suppose, that this reproach is as unjust as it is unkind; and that, of the geniuses which adorn the present age, America contributes its full share. [Compared to the much larger populations of European countries.]

“Yes,” he said. “But these things (the solutions to problems in solid geometry such as the duplication of the cube) do not seem to have been discovered yet.” “There are two reasons for this,” I said. “Because no city holds these things in honour, they are investigated in a feeble way, since they are difficult; and the investigators need an overseer, since they will not find the solutions without one. First, it is hard to get such an overseer, and second, even if one did, as things are now those who investigate these things would not obey him, because of their arrogance. If however a whole city, which did hold these things in honour, were to oversee them communally, the investigators would be obedient, and when these problems were investigated continually and with eagerness, their solutions would become apparent.”

[About research with big particle accelerators such as the Large Hadron Collider.] I think the primary justification for this sort of science that we do is fundamental human curiosity. ... It's true, of course, that every previous generation that's made some breakthrough in understanding nature has seen those discoveries translated into new technologies, new possibilities for the human race. That may well happen with the Higgs boson. Quite frankly, at the moment I don't see how you can use the Higgs boson for anything useful.

[As a youth, fiddling in my home laboratory] I discovered a formula for the frequency of a resonant circuit which was 2π x sqrt(LC) where L is the inductance and C the capacitance of the circuit. And there was π, and where was the circle? … I still don’t quite know where that circle is, where that π comes from.

[At DuPont,] I was very fortunate that I worked under men who were very much interested in making discoveries and inventions. They were very much interested in what they were doing, and they left me alone. And I was able to experiment on my own, and I found this very stimulating. It appealed to the creative person in me.

[Chemistry] laboratory work was my first challenge. ... I still carry the scars of my first discovery—that test-tubes are fragile.

[Concerning] phosphorescent bodies, and in particular to uranium salts whose phosphorescence has a very brief duration. With the double sulfate of uranium and potassium ... I was able to perform the following experiment: One wraps a Lumière photographic plate with a bromide emulsion in two sheets of very thick black paper, such that the plate does not become clouded upon being exposed to the sun for a day. One places on the sheet of paper, on the outside, a slab of the phosphorescent substance, and one exposes the whole to the sun for several hours. When one then develops the photographic plate, one recognizes that the silhouette of the phosphorescent substance appears in black on the negative. If one places between the phosphorescent substance and the paper a piece of money or a metal screen pierced with a cut-out design, one sees the image of these objects appear on the negative. One can repeat the same experiments placing a thin pane of glass between the phosphorescent substance and the paper, which excludes the possibility of chemical action due to vapors which might emanate from the substance when heated by the sun's rays. One must conclude from these experiments that the phosphorescent substance in question emits rays which pass through the opaque paper and reduces silver salts.
[Although the sun is irrelevant, and he misinterprets the role of phosphorescence, he has discovered the effect of radioactivity.]

[D]iscovery should come as an adventure rather than as the result of a logical process of thought. Sharp, prolonged thinking is necessary that we may keep on the chosen road but it does not itself necessarily lead to discovery. The investigator must be ready and on the spot when the light comes from whatever direction.

[Davy's] March of Glory, which he has run for the last six weeks—within which time by the aid and application of his own great discovery, of the identity of electricity and chemical attractions, he has placed all the elements and all their inanimate combinations in the power of man; having decomposed both the Alkalies, and three of the Earths, discovered as the base of the Alkalies a new metal... Davy supposes there is only one power in the world of the senses; which in particles acts as chemical attractions, in specific masses as electricity, & on matter in general, as planetary Gravitation... when this has been proved, it will then only remain to resolve this into some Law of vital Intellect—and all human knowledge will be Science and Metaphysics the only Science.
In November 1807 Davy gave his famous Second Bakerian Lecture at the Royal Society, in which he used Voltaic batteries to “decompose, isolate and name” several new chemical elements, notably sodium and potassium.

[Edison] definitely ended the distinction between the theoretical man of science and the practical man of science, so that today we think of scientific discoveries in connection with their possible present or future application to the needs of man. He took the old rule-of-thumb methods out of industry and substituted exact scientific knowledge, while, on the other hand, he directed scientific research into useful channels.

[I doubt that in today's world, I and Francis Crick would ever have had our Eureka moment.] I recently went to my staircase at Clare College, Cambridge and there were women there! he said, with an enormous measure of retrospective sexual frustration. There have been a lot of convincing studies recently about the loss of productivity in the Western male. It may be that entertainment culture now is so engaging that it keeps people satisfied. We didn't have that. Science was much more fun than listening to the radio. When you are 16 or 17 and in that inherently semi-lonely period when you are deciding whether to be an intellectual, many now don't bother.
(Response when asked how he thought the climate of scientific research had changed since he made his discovery of the structure of life in 1953.)

[In the case of research director, Willis R. Whitney, whose style was to give talented investigators as much freedom as possible, you may define “serendipity” as] the art of profiting from unexpected occurrences. When you do things in that way you get unexpected results. Then you do something else and you get unexpected results in another line, and you do that on a third line and then all of a sudden you see that one of these lines has something to do with the other. Then you make a discovery that you never could have made by going on a direct road.

[Isaac Newton] regarded the Universe as a cryptogram set by the Almighty—just as he himself wrapt the discovery of the calculus in a cryptogram when he communicated with Leibniz. By pure thought, by concentration of mind, the riddle, he believed, would be revealed to the initiate.

[It] is not the nature of things for any one man to make a sudden, violent discovery; science goes step by step and every man depends on the work of his predecessors. When you hear of a sudden unexpected discovery—a bolt from the blue—you can always be sure that it has grown up by the influence of one man or another, and it is the mutual influence which makes the enormous possibility of scientific advance. Scientists are not dependent on the ideas of a single man, but on the combined wisdom of thousands of men, all thinking of the same problem and each doing his little bit to add to the great structure of knowledge which is gradually being erected.

[J.J.] Sylvester’s methods! He had none. “Three lectures will be delivered on a New Universal Algebra,” he would say; then, “The course must be extended to twelve.” It did last all the rest of that year. The following year the course was to be Substitutions-Théorie, by Netto. We all got the text. He lectured about three times, following the text closely and stopping sharp at the end of the hour. Then he began to think about matrices again. “I must give one lecture a week on those,” he said. He could not confine himself to the hour, nor to the one lecture a week. Two weeks were passed, and Netto was forgotten entirely and never mentioned again. Statements like the following were not unfrequent in his lectures: “I haven’t proved this, but I am as sure as I can be of anything that it must be so. From this it will follow, etc.” At the next lecture it turned out that what he was so sure of was false. Never mind, he kept on forever guessing and trying, and presently a wonderful discovery followed, then another and another. Afterward he would go back and work it all over again, and surprise us with all sorts of side lights. He then made another leap in the dark, more treasures were discovered, and so on forever.

[M]y work, which I’ve done for a long time, was not pursued in order to gain the praise I now enjoy, but chiefly from a craving after knowledge, which I notice resides in me more than in most other men. And therewithal, whenever I found out anything remarkable, I have thought it my duty to put down my discovery on paper, so that all ingenious people might be informed thereof.

[Mathematics is] the study of ideal constructions (often applicable to real problems), and the discovery thereby of relations between the parts of these constructions, before unknown.

[Misquotation? Probably not by Einstein.] We owe a lot to the Indians, who taught us how to count, without which no worthwhile scientific discovery could have been made.

[On the practical applications of particle physics research with the Large Hadron Collider.] Sometimes the public says, “What's in it for Numero Uno? Am I going to get better television reception? Am I going to get better Internet reception?” Well, in some sense, yeah. … All the wonders of quantum physics were learned basically from looking at atom-smasher technology. … But let me let you in on a secret: We physicists are not driven to do this because of better color television. … That's a spin-off. We do this because we want to understand our role and our place in the universe.

[The more science discovers and] the more comprehension it gives us of the mechanisms of existence, the more clearly does the mystery of existence itself stand out.

[This] may prove to be the beginning of some embracing generalization, which will throw light, not only on radioactive processes, but on elements in general and the Periodic Law.... Chemical homogeneity is no longer a guarantee that any supposed element is not a mixture of several of different atomic weights, or that any atomic weight is not merely a mean number.

[Urbain Jean Joseph] Le Verrier—without leaving his study, without even looking at the sky—had found the unknown planet [Neptune] solely by mathematical calculation, and, as it were, touched it with the tip of his pen!

[Pechblende] einer eigenthümlichen, selbstständigen metallischen Substanz bestehe. Es fallen folglich auch deren bisherige Benennungen, als: Ресhblende Eisenpecherz, hinweg, welche nun durch einen neuen ausschliessend bezeichnenden Namen zu ersetzen sind. Ich habe dazu den Namen: Uranerz (Uranium) erwählt; zu einigem Andenken, dass die chemische Ausfindung dieses neuen Metallkörpers in die Epoche der astronomischen. Entdeckung des Planeten Uranus gefallen sei.
[Pitchblende] consists of a peculiar, distinct, metallic substance. Therefore its former denominations, pitch-blende, pitch-iron-ore, &c. are no longer applicable, and must be supplied by another more appropriate name.—I have chosen that of uranite, (Uranium), as a kind of memorial, that the chemical discovery of this new metal happened in the period of the astronomical discovery of the new planet Uranus.

[Probably not a direct quote] Experimental confirmation of a prediction is merely a measurement. An experiment disproving a prediction is a discovery.

Connaître, découvrir, communiquer—telle est, au fond, notre honorable destinée.
To get to know, to discover, to publish—this is the destiny of a scientist.

Deviner avant de démontrer! Ai-je besoin de rappeler que c'est ainsi que se sont faites toutes les découvertes importantes.
Guessing before proving! Need I remind you that it is so that all important discoveries have been made?

Die Natur hates sich nicht angelegen sein lassen, uns die Auffindung ihrer Gesetze bequem zu machen.
Nature did not deem it her business to make the discovery of her laws easy for us.

Discovery always carries an honorific connotation. It is the stamp of approval on a finding of lasting value. Many laws and theories have come and gone in the history of science, but they are not spoken of as discoveries. Kepler is said to have discovered the laws of planetary motion named after him, but no the many other 'laws' which he formulated. ... Theories are especially precarious, as this century profoundly testifies. World views can and do often change. Despite these difficulties, it is still true that to count as a discovery a finding must be of at least relatively permanent value, as shown by its inclusion in the generally accepted body of scientific knowledge.

Dogbert: Scientists have discovered the gene that makes some people love golf.
Dilbert: How can they tell it’s the golf gene?
Dogbert: It’s plaid and it lies.

Et j’espère que nos neveux me sauront gré, non seulement des choses que j'ai ici expliquées, mais aussi de celles que j'ai omises volontairement, afin de leur laisser le plaisir de les inventer.
I hope that posterity will judge me kindly, not only as to the things which I have explained, but also as to those which I have intentionally omitted so as to leave to others the pleasure of discovery.

Eureka! Eureka!
I have found it!

La nature veut que dans certains temps les hommes se succèdent les uns aux autres par le moyen de la mort; il leur est permis de se défendre contr’elle jusqu’à un certain point; mais passé cela, on aura beau faire de nouvelles découvertes dans l’Anatomie, on aura beau pénétrer de plus en plus dans les secrets de la structure du corps humain, on ne prendra point la Nature pour dupe, on mourra comme à l’ordinaire.
Nature intends that at fixed periods men should succeed each other by the instrumentality of death. They are allowed to keep it at bay up to a certain point; but when that is passed, it will be of no use to make new discoveries in anatomy, or to penetrate more and more into the secrets of the structure of the human body; we shall never outwit nature, we shall die as usual.

Le seul véritable voyage ... ce ne serait pas d’aller vers de nouveaux paysages, mais d’avoir d’autres yeux, de voir l’univers avec les yeux d’un autre, de cent autres, de voir les cent univers que chacun d’eux voit …
The only true voyage of discovery … would be not to visit new landscapes, but to possess other eyes, to see the universe through the eyes of another, of a hundred others, to see the hundred universes that each of them sees.
[Also often seen translated in the shortened form: 'The only real voyage of discovery consists not in seeing new landscapes, but in having new eyes.']

Neue Phaenomena zu erklären, dieses macht meine Sorgen aus, und wie froh ist der Forscher, wenn er das so fleissig Gesuche findet, eine Ergötzung wobei das Herz lacht.
To explain new phenomena, that is my task; and how happy is the scientist when he finds what he so diligently sought, a pleasure that gladdens the heart.

On se persuade mieux, pour l’ordinaire, par les raisons qu’on a soi-même trouvées, que par celles qui sont venues dans l’esprit des autres.
We are generally more effectually persuaded by reasons we have ourselves discovered than by those which have occurred to others.

Question: Explain why, in order to cook food by boiling, at the top of a high mountain, you must employ a different method from that used at the sea level.
Answer: It is easy to cook food at the sea level by boiling it, but once you get above the sea level the only plan is to fry it in its own fat. It is, in fact, impossible to boil water above the sea level by any amount of heat. A different method, therefore, would have to be employed to boil food at the top of a high mountain, but what that method is has not yet been discovered. The future may reveal it to a daring experimentalist.

~~[Misattributed ?]~~ Mathematical discoveries, like springtime violets in the woods, have their season which no human can hasten or retard.

2³⁰(2³¹-1) ... is the greatest perfect number known at present, and probably the greatest that ever will be discovered; for; as they are merely curious without being useful, it is not likely that any person will attempt to find a number beyond it.

A discovery in science, or a new theory, even when it appears most unitary and most all-embracing, deals with some immediate element of novelty or paradox within the framework of far vaster, unanalysed, unarticulated reserves of knowledge, experience, faith, and presupposition. Our progress is narrow; it takes a vast world unchallenged and for granted. This is one reason why, however great the novelty or scope of new discovery, we neither can, nor need, rebuild the house of the mind very rapidly. This is one reason why science, for all its revolutions, is conservative. This is why we will have to accept the fact that no one of us really will ever know very much. This is why we shall have to find comfort in the fact that, taken together, we know more and more.

A discovery is generally an unforeseen relation not included in theory.

A discovery is like falling in love and reaching the top of a mountain after a hard climb all in one, an ecstasy not induced by drugs but by the revelation of a face of nature that no one has seen before and that often turns out to be more subtle and wonderful than anyone had imagined.

A discovery must be, by definition, at variance with existing knowledge. During my lifetime, I made two. Both were rejected offhand by the popes of the field. Had I predicted these discoveries in my applications, and had those authorities been my judges, it is evident what their decisions would have been.

A drop from the nose of Fleming, who had a cold, fell onto an agar plate where large yellow colonies of a contaminant had grown, and lysosyme was discovered. He made this important discovery because when he saw that the colonies of the contaminant were fading, his mind went straight to the right cause of the phenomenon he was observing—that the drop from his nose contained a lytic substance. And also immediately, he thought that this substance might be present in many secretions and tissues of the body. And he found this was so—the substance was in tears, saliva, leucocytes, skin, fingernails, mother's milk—thus very widely distributed in amounts and also in plants.

A famous name has this peculiarity that it becomes gradually smaller especially in natural sciences where each succeeding discovery invariably overshadows what precedes.

A few days afterwards, I went to him [the same actuary referred to in another quote] and very gravely told him that I had discovered the law of human mortality in the Carlisle Table, of which he thought very highly. I told him that the law was involved in this circumstance. Take the table of the expectation of life, choose any age, take its expectation and make the nearest integer a new age, do the same with that, and so on; begin at what age you like, you are sure to end at the place where the age past is equal, or most nearly equal, to the expectation to come. “You don’t mean that this always happens?”—“Try it.” He did try, again and again; and found it as I said. “This is, indeed, a curious thing; this is a discovery!” I might have sent him about trumpeting the law of life: but I contented myself with informing him that the same thing would happen with any table whatsoever in which the first column goes up and the second goes down.

A few months after a devastating defeat at Fredericksburg,… President Abraham Lincoln signed into law an act creating the National Academy of Sciences—in the midst of civil war. Lincoln refused to accept that our nation’s sole purpose was mere survival. He created this academy, founded the land grant colleges, and began the work of the transcontinental railroad, believing that we must add—and I quote—“the fuel of interest to the fire of genius in the discovery … of new and useful things.”

A good method of discovery is to imagine certain members of a system removed and then see how what is left would behave: for example, where would we be if iron were absent from the world: this is an old example.

A great discovery solves a great problem, but there is a grain of discovery in the solution of any problem. Your problem may be modest, but if it challenges your curiosity and brings into play your inventive faculties, and if you solve it by your own means, you may experience the tension and enjoy the triumph of discovery.

A lot of prizes have been awarded for showing the universe is not as simple as we might have thought.

A man of genius makes no mistakes. His errors are volitional and are the portals of discovery.

A mathematical truth is timeless, it does not come into being when we discover it. Yet its discovery is a very real event, it may be an emotion like a great gift from a fairy.

A mathematician’s work is mostly a tangle of guesswork, analogy, wishful thinking and frustration, and proof, far from being the core of discovery, is more often than not a way of making sure that our minds are not playing tricks.

A moment’s consideration of this case shows what a really great advance in the theory and practise of breeding has been obtained through the discovery of Mendel’s law. What a puzzle this case would have presented to the biologist ten years ago! Agouti crossed with chocolate gives in the second filial generation (not in the first) four varieties, viz., agouti, chocolate, black and cinnamon. We could only have shaken our heads and looked wise (or skeptical).
Then we had no explanation to offer for such occurrences other than the “instability of color characters under domestication,” the “effects of inbreeding,” “maternal impressions.” Serious consideration would have been given to the proximity of cages containing both black and cinnamon-agouti mice.
Now we have a simple, rational explanation, which anyone can put to the test. We are able to predict the production of new varieties, and to produce them.
We must not, of course, in our exuberance, conclude that the powers of the hybridizer know no limits. The result under consideration consists, after all, only in the making of new combinations of unit characters, but it is much to know that these units exist and that all conceivable combinations of them are ordinarily capable of production. This valuable knowledge we owe to the discoverer and to the rediscoverers of Mendel’s law.

A new era of ocean exploration can yield discoveries that will help inform everything from critical medical advances to sustainable forms of energy. Consider that AZT, an early treatment for HIV, is derived from a Caribbean reef sponge, or that a great deal of energy—from offshore wind, to OTEC (ocean thermal energy conservation), to wind and wave energy—is yet untapped in our oceans.

A number of years ago, when I was a freshly-appointed instructor, I met, for the first time, a certain eminent historian of science. At the time I could only regard him with tolerant condescension.
I was sorry of the man who, it seemed to me, was forced to hover about the edges of science. He was compelled to shiver endlessly in the outskirts, getting only feeble warmth from the distant sun of science- in-progress; while I, just beginning my research, was bathed in the heady liquid heat up at the very center of the glow.
In a lifetime of being wrong at many a point, I was never more wrong. It was I, not he, who was wandering in the periphery. It was he, not I, who lived in the blaze.
I had fallen victim to the fallacy of the “growing edge;” the belief that only the very frontier of scientific advance counted; that everything that had been left behind by that advance was faded and dead.
But is that true? Because a tree in spring buds and comes greenly into leaf, are those leaves therefore the tree? If the newborn twigs and their leaves were all that existed, they would form a vague halo of green suspended in mid-air, but surely that is not the tree. The leaves, by themselves, are no more than trivial fluttering decoration. It is the trunk and limbs that give the tree its grandeur and the leaves themselves their meaning.
There is not a discovery in science, however revolutionary, however sparkling with insight, that does not arise out of what went before. “If I have seen further than other men,” said Isaac Newton, “it is because I have stood on the shoulders of giants.”

A political law or a scientific truth may be perilous to the morals or the faith of individuals; but it cannot on this ground be resisted by the Church. … A discovery may be made in science which will shake the faith of thousands; yet religion cannot regret it or object to it. The difference in this respect between a true and a false religion is, that one judges all things by the standard of their truth, the other by the touchstone of its own interests. A false religion fears the progress of all truth; a true religion seeks and recognises truth wherever it can be found.

A possible explanation for the observed excess noise is the one given by Dicke, Peebles, Roll, and Wilkinson (1965) in a companion letter in this issue.
[The low-key announcement of the detection of the cosmic microwave background radiation which is the afterglow of the Big Bang. Co-author with Robert Wilson. They received the 1978 Nobel Prize for their discovery.]

A scientifically unimportant discovery is one which, however true and however interesting for other reasons, has no consequences for a system of theory with which scientists in that field are concerned.

A young person who reads a science book is confronted with a number of facts, x = ma … ma - me² … You never see in the scientific books what lies behind the discovery—the struggle and the passion of the person, who made that discovery.

About eight days ago I discovered that sulfur in burning, far from losing weight, on the contrary, gains it; it is the same with phosphorus; this increase of weight arises from a prodigious quantity of air that is fixed during combustion and combines with the vapors. This discovery, which I have established by experiments, that I regard as decisive, has led me to think that what is observed in the combustion of sulfur and phosphorus may well take place in the case of all substances that gain in weight by combustion and calcination; and I am persuaded that the increase in weight of metallic calxes is due to the same cause... This discovery seems to me one of the most interesting that has been made since Stahl and since it is difficult not to disclose something inadvertently in conversation with friends that could lead to the truth I have thought it necessary to make the present deposit to the Secretary of the Academy to await the time I make my experiments public.

About the year 1772, being then an apprentice to a wheel-wright, or wagon maker, I laboured to discover some means of propelling land carriages without animal power. … one of my brothers [told me of] blacksmith’s boys, who, for amusement, had stopped up the touch hole of a gun barrel, then put in about a gill of water, and rammed down a tight wad; after which they put the breech in the smith’s fire, when it discharged itself with as loud a crack as if it had been loaded with powder. It immediately occurred to me, that here was the power to propel any wagon, if I could only apply it.

Accurate and minute measurement seems to the non-scientific imagination, a less lofty and dignified work than looking for something new. But nearly all the grandest discoveries of science have been but the rewards of accurate measurement and patient long-continued labour in the minute sifting of numerical results.

After all, most men are incapable of deciding for themselves, and have got to have a leader somewhere. If the new discoveries in mass suggestion enable us to make government easier, not only political, but moral and aesthetic, why not welcome them like other useful inventions? Why should science be limited to improvements in our control over nature, and exclude the most important part of our environment, our fellows? Get on the inside, join, as I used to be told, some party, and learn where the ropes come down within your reach. Adopt the high calling of Manipulator and save the State.
Such Machiavellis are not confined to Russia and Italy; one may find them all about even in this Land of the Free. … Still there remains in me a strange misgiving about making use of one’s fellows through an appeal to their weaknesses, even when all you do is to select their objects for them. In the elegant diction of Mr. Mencken, and in spite of the great weight of his authority, a government of the boobs, for the boobs and by the boobs to me still has its morbid charms.

After long reflection in solitude and meditation, I suddenly had the idea, during the year 1923, that the discovery made by Einstein in 1905 should be generalised by extending it to all material particles and notably to electrons.

After seeking in vain for the construction of a perpetual motion machine, the relations were investigated which must subsist between the forces of nature if such a machine is to be impossible; and this inverted question led to the discovery of the law of the conservation of energy, which, again, explained the impossibility of perpetual motion in the sense originally intended.

After the discovery of spectral analysis no one trained in physics could doubt the problem of the atom would be solved when physicists had learned to understand the language of spectra. So manifold was the enormous amount of material that has been accumulated in sixty years of spectroscopic research that it seemed at first beyond the possibility of disentanglement. An almost greater enlightenment has resulted from the seven years of Röntgen spectroscopy, inasmuch as it has attacked the problem of the atom at its very root, and illuminates the interior. What we are nowadays hearing of the language of spectra is a true 'music of the spheres' in order and harmony that becomes ever more perfect in spite of the manifold variety. The theory of spectral lines will bear the name of Bohr for all time. But yet another name will be permanently associated with it, that of Planck. All integral laws of spectral lines and of atomic theory spring originally from the quantum theory. It is the mysterious organon on which Nature plays her music of the spectra, and according to the rhythm of which she regulates the structure of the atoms and nuclei.

All creation is a mine, and every man a miner.
The whole earth, and all within it, upon it, and round about it, including himself … are the infinitely various “leads” from which, man, from the first, was to dig out his destiny.

All fossil anthropoids found hitherto have been known only from mandibular or maxillary fragments, so far as crania are concerned, and so the general appearance of the types they represented had been unknown; consequently, a condition of affairs where virtually the whole face and lower jaw, replete with teeth, together with the major portion of the brain pattern, have been preserved, constitutes a specimen of unusual value in fossil anthropoid discovery. Here, as in Homo rhodesiensis, Southern Africa has provided documents of higher primate evolution that are amongst the most complete extant. Apart from this evidential completeness, the specimen is of importance because it exhibits an extinct race of apes intermediate between living anthropoids and man ... Whether our present fossil is to be correlated with the discoveries made in India is not yet apparent; that question can only be solved by a careful comparison of the permanent molar teeth from both localities. It is obvious, meanwhile, that it represents a fossil group distinctly advanced beyond living anthropoids in those two dominantly human characters of facial and dental recession on one hand, and improved quality of the brain on the other. Unlike Pithecanthropus, it does not represent an ape-like man, a caricature of precocious hominid failure, but a creature well advanced beyond modern anthropoids in just those characters, facial and cerebral, which are to be anticipated in an extinct link between man and his simian ancestor. At the same time, it is equally evident that a creature with anthropoid brain capacity and lacking the distinctive, localised temporal expansions which appear to be concomitant with and necessary to articulate man, is no true man. It is therefore logically regarded as a man-like ape. I propose tentatively, then, that a new family of Homo-simidæ be created for the reception of the group of individuals which it represents, and that the first known species of the group be designated Australopithecus africanus, in commemoration, first, of the extreme southern and unexpected horizon of its discovery, and secondly, of the continent in which so many new and important discoveries connected with the early history of man have recently been made, thus vindicating the Darwinian claim that Africa would prove to be the cradle of mankind.

All great achievements in science start from intuitive knowledge, namely, in axioms, from which deductions are then made. … Intuition is the necessary condition for the discovery of such axioms.

All great discoveries are made by men whose feelings run ahead of their thinking.

All great scientists have, in a certain sense, been great artists; the man with no imagination may collect facts, but he cannot make great discoveries.

All human affairs follow nature's great analogue, the growth of vegetation. There are three periods of growth in every plant. The first, and slowest, is the invisible growth by the root; the second and much accelerated is the visible growth by the stem; but when root and stem have gathered their forces, there comes the third period, in which the plant quickly flashes into blossom and rushes into fruit.
The beginnings of moral enterprises in this world are never to be measured by any apparent growth. ... At length comes the sudden ripeness and the full success, and he who is called in at the final moment deems this success his own. He is but the reaper and not the labourer. Other men sowed and tilled and he but enters into their labours.

All human discoveries seem to be made only for the purpose of confirming more strongly the truths come from on high, and contained in the sacred writings.

All knowledge is profitable; profitable in its ennobling effect on the character, in the pleasure it imparts in its acquisition, as well as in the power it gives over the operations of mind and of matter. All knowledge is useful; every part of this complex system of nature is connected with every other. Nothing is isolated. The discovery of to-day, which appears unconnected with any useful process, may, in the course of a few years, become the fruitful source of a thousand inventions.

All science is concerned with the relationship of cause and effect. Each scientific discovery increases man’s ability to predict the consequences of his actions and thus his ability to control future events.

All that concerns the Mediterranean is of the deepest interest to civilized man, for the history of its progress is the history of the development of the world; the memory of the great men who have lived and died around its banks; the recollection of the undying works that have come thence to delight us for ever; the story of patient research and brilliant discoveries connected with every physical phenomenon presented by its waves and currents, and with every order of creatures dwelling in and around its waters.

All the modern higher mathematics is based on a calculus of operations, on laws of thought. All mathematics, from the first, was so in reality; but the evolvers of the modern higher calculus have known that it is so. Therefore elementary teachers who, at the present day, persist in thinking about algebra and arithmetic as dealing with laws of number, and about geometry as dealing with laws of surface and solid content, are doing the best that in them lies to put their pupils on the wrong track for reaching in the future any true understanding of the higher algebras. Algebras deal not with laws of number, but with such laws of the human thinking machinery as have been discovered in the course of investigations on numbers. Plane geometry deals with such laws of thought as were discovered by men intent on finding out how to measure surface; and solid geometry with such additional laws of thought as were discovered when men began to extend geometry into three dimensions.

All the truths of mathematics are linked to each other, and all means of discovering them are equally admissible.

Almost all great advances have sprung originally from disinterested motives. Scientific discoveries have been made for their own sake and not for their utilization, and a race of men without a disinterested love of knowledge would never have achieved our present scientific technique. … Faraday, Maxwell, and Hertz, so far as can be discovered, never for a moment considered the possibility of any practical application of their investigations.

Almost all the greatest discoveries in astronomy have resulted from what we have elsewhere termed Residual Phenomena, of a qualitative or numerical kind, of such portions of the numerical or quantitative results of observation as remain outstanding and unaccounted for, after subducting and allowing for all that would result from the strict application of known principles.

Although Rick [Richard Smalley] made enormous contributions to science, I believe his worldwide contributions in making so many of us aware of the huge energy problem is even greater and longer-lasting than the beautiful science that he discovered.

An apple falls in front of Newton, a pot boils before Papin, a flaming sheet of paper floats before the eyes of Montgolfier. At intervals a discovery bursts forth like a mine explosion in the deeps of science, and a whole ledge of prejudice crumbles, and the living rock of truth is suddenly laid bare.

An experiment is an observation that can be repeated, isolated and varied. The more frequently you can repeat an observation, the more likely are you to see clearly what is there and to describe accurately what you have seen. The more strictly you can isolate an observation, the easier does your task of observation become, and the less danger is there of your being led astray by irrelevant circumstances, or of placing emphasis on the wrong point. The more widely you can vary an observation, the more clearly will the uniformity of experience stand out, and the better is your chance of discovering laws.

An inventor is an opportunist, one who takes occasion by the hand; who, having seen where some want exists, successfully applies the right means to attain the desired end. The means may be largely, or even wholly, something already known, or there may be a certain originality or discovery in the means employed. But in every case the inventor uses the work of others. If I may use a metaphor, I should liken him to the man who essays the conquest of some virgin alp. At the outset he uses the beaten track, and, as he progresses in the ascent, he uses the steps made by those who have preceded him, whenever they lead in the right direction; and it is only after the last footprints have died out that he takes ice-axe in hand and cuts the remaining steps, few or many, that lift him to the crowning height which is his goal.

Analysis and natural philosophy owe their most important discoveries to this fruitful means, which is called induction. Newton was indebted to it for his theorem of the binomial and the principle of universal gravity.

Anatomists have ever been engaged in contention. And indeed, if a man has not such a degree of enthusiasm, and love of the art, as will make him impatient of unreasonable opposition and of encroachments upon his discoveries and his reputation, he will hardly become considerable in Anatomy or in any branch of natural knowledge.

Another argument of hope may be drawn from this–that some of the inventions already known are such as before they were discovered it could hardly have entered any man's head to think of; they would have been simply set aside as impossible. For in conjecturing what may be men set before them the example of what has been, and divine of the new with an imagination preoccupied and colored by the old; which way of forming opinions is very fallacious, for streams that are drawn from the springheads of nature do not always run in the old channels.

Any scientist of any age who wants to make important discoveries must study important problems. Dull or piffling problems yield dull or piffling answers. It is not not enough that a problem should be “interesting.” … The problem must be such that it matters what the answer is—whether to science generally or to mankind.

Applied research generates improvements, not breakthroughs. Great scientific advances spring from pure research. Even scientists renowned for their “useful” applied discoveries often achieved success only when they abandoned their ostensible applied-science goal and allowed their minds to soar—as when Alexander Fleming, “just playing about,” refrained from throwing away green molds that had ruined his experiment, studied them, and discovered penicillin. Or when C. A. Clarke, a physician affiliated with the University of Liverpool, became intrigued in the 1950s by genetically created color patterns that emerged when he cross-bred butterflies as a hobby. His fascination led him—“by the pleasant route of pursuing idle curiosity”—to the successful idea for preventing the sometimes fatal anemia that threatened babies born of a positive-Rhesus-factor father and a negative-Rhesus-factor mother.

Archimedes had discovered the truth about several important natural laws, but more significant—at least from Galileo’s standpoint—was Archimedes’s discovery of a way for a scientist to solve problems: first separating what he truly wants to solve from irrelevant externals and then attacking the core of the problem with boldness and imagination. Galileo realized that this approach was suitable for his own studies.

Archimedes said Eureka,
Cos in English he weren't too aversed in,
when he discovered that the volume of a body in the bath,
is equal to the stuff it is immersed in,
That is the law of displacement,
Thats why ships don't sink,
Its a shame he weren't around in 1912,
The Titanic would have made him think.

Ardent desire for knowledge, in fact, is the one motive attracting and supporting investigators in their efforts; and just this knowledge, really grasped and yet always flying before them, becomes at once their sole torment and their sole happiness. Those who do not know the torment of the unknown cannot have the joy of discovery which is certainly the liveliest that the mind of man can ever feel.

Aristotle discovered all the half-truths which were necessary to the creation of science.

Arithmetic must be discovered in just the same sense in which Columbus discovered the West Indies, and we no more create numbers than he created the Indians.

Art is more godlike than science. Science discovers; art creates.

Art, science, discovery and invention, startle and bewilder us at every turn, by their rapid, vast and wonderful achievements. These forces have made men lords where they were vassals, masters where they were slaves, and kings where they were subjects. They have abolished the limitations of time and space and have brought the ends of the earth together.

As a boy I had liked both drawing and physics, and I always abhorred the role of being a spectator. In 1908, when I was 15, I designed, built and flew a toy model airplane which won the then-famous James Gordon Bennett Cup. By 16 I had discovered that design could be fun and profitable, and this lesson has never been lost on me.

As every circumstance relating to so capital a discovery as this (the greatest, perhaps, that has been made in the whole compass of philosophy, since the time of Sir Isaac Newton) cannot but give pleasure to all my readers, I shall endeavour to gratify them with the communication of a few particulars which I have from the best authority. The Doctor [Benjamin Franklin], after having published his method of verifying his hypothesis concerning the sameness of electricity with the matter lightning, was waiting for the erection of a spire in Philadelphia to carry his views into execution; not imagining that a pointed rod, of a moderate height, could answer the purpose; when it occurred to him, that, by means of a common kite, he could have a readier and better access to the regions of thunder than by any spire whatever. Preparing, therefore, a large silk handkerchief, and two cross sticks, of a proper length, on which to extend it, he took the opportunity of the first approaching thunder storm to take a walk into a field, in which there was a shed convenient for his purpose. But dreading the ridicule which too commonly attends unsuccessful attempts in science, he communicated his intended experiment to no body but his son, who assisted him in raising the kite.
The kite being raised, a considerable time elapsed before there was any appearance of its being electrified. One very promising cloud passed over it without any effect; when, at length, just as he was beginning to despair of his contrivance, he observed some loose threads of the hempen string to stand erect, and to avoid one another, just as if they had been suspended on a common conductor. Struck with this promising appearance, he inmmediately presented his knuckle to the key, and (let the reader judge of the exquisite pleasure he must have felt at that moment) the discovery was complete. He perceived a very evident electric spark. Others succeeded, even before the string was wet, so as to put the matter past all dispute, and when the rain had wetted the string, he collected electric fire very copiously. This happened in June 1752, a month after the electricians in France had verified the same theory, but before he had heard of any thing that they had done.

As the component parts of all new machines may be said to be old[,] it is a nice discriminating judgment, which discovers that a particular arrangement will produce a new and desired effect. ... Therefore, the mechanic should sit down among levers, screws, wedges, wheels, etc. like a poet among the letters of the alphabet, considering them as the exhibition of his thoughts; in which a new arrangement transmits a new idea to the world.

Astronomy is older than physics. In fact, it got physics started by showing the beautiful simplicity of the motion of the stars and planets, the understanding of which was the beginning of physics. But the most remarkable discovery in all of astronomy is that the stars are made of atoms of the same kind as those on the earth.

Astronomy is perhaps the science whose discoveries owe least to chance, in which human understanding appears in its whole magnitude, and through which man can best learn how small he is.

Astronomy may be revolutionized more than any other field of science by observations from above the atmosphere. Study of the planets, the Sun, the stars, and the rarified matter in space should all be profoundly influenced by measurements from balloons, rockets, probes and satellites. ... In a new adventure of discovery no one can foretell what will be found, and it is probably safe to predict that the most important new discovery that will be made with flying telescopes will be quite unexpected and unforeseen. (1961)

At last have made wonderful discovery in valley; a magnificent tomb with seals intact; re-covered same for your arrival; congratulations.

At lunch Francis [Crick] winged into the Eagle to tell everyone within hearing distance that we had found the secret of life.

At the Egyptian city of Naucratis there was a famous old god whose name was Theuth; the bird which is called the Ibis was sacred to him, and he was the inventor of many arts, such as arithmetic and calculation and geometry and astronomy and draughts and dice, but his great discovery was the use of letters.

At the moment I am occupied by an investigation with Kirchoff which does not allow us to sleep. Kirchoff has made a totally unexpected discovery, inasmuch as he has found out the cause for the dark lines in the solar spectrum and can produce these lines artificially intensified both in the solar spectrum and in the continuous spectrum of a flame, their position being identical with that of Fraunhofer’s lines. Hence the path is opened for the determination of the chemical composition of the Sun and the fixed stars.

At the moment I am occupied by an investigation with Kirchoff which does not allow us to sleep. Kirchoff has made a totally unexpected discovery, inasmuch as he has found out the cause for the dark lines in the solar spectrum and can produce these lines artificially intensified both in the solar spectrum and in the continuous spectrum of a flame, their position being identical with that of Fraunhofer’s lines. Hence the path is opened for the determination of the chemical composition of the Sun and the fixed stars.

At the voice of comparative anatomy, every bone, and fragment of a bone, resumed its place. I cannot find words to express the pleasure I have in seeing, as I discovered one character, how all the consequences, which I predicted from it, were successively confirmed; the feet were found in accordance with the characters announced by the teeth; the teeth in harmony with those indicated beforehand by the feet; the bones of the legs and thighs, and every connecting portion of the extremities, were found set together precisely as I had arranged them, before my conjectures were verified by the discovery of the parts entire: in short, each species was, as it were, reconstructed from a single one of its component elements.

At this point, however, I have no intention whatever of criticizing the false teachings of Galen, who is easily first among the professors of dissection, for I certainly do not wish to start off by gaining a reputation for impiety toward him, the author of all good things, or by seeming insubordinate to his authority. For I am well aware how upset the practitioners (unlike the followers of Aristotle) invariably become nowadays, when they discover in the course of a single dissection that Galen has departed on two hundred or more occasions from the true description of the harmony, function, and action of the human parts, and how grimly they examine the dissected portions as they strive with all the zeal at their command to defend him. Yet even they, drawn by their love of truth, are gradually calming down and placing more faith in their own not ineffective eyes and reason than in Galen’s writings.

Before the promulgation of the periodic law the chemical elements were mere fragmentary incidental facts in nature; there was no special reason to expect the discovery of new elements, and the new ones which were discovered from time to time appeared to be possessed of quite novel properties. The law of periodicity first enabled us to perceive undiscovered elements at a distance which formerly were inaccessible to chemical vision, and long ere they were discovered new elements appeared before our eyes possessed of a number of well-defined properties.

Behind and permeating all our scientific activity, whether in critical analysis or in discovery, there is an elementary and overwhelming faith in the possibility of grasping the real world with out concepts, and, above all, faith in the truth over which we have no control but in the service of which our rationality stands or falls. Faith and intrinsic rationality are interlocked with one another

Being also in accord with Goethe that discoveries are made by the age and not by the individual, I should consider the instances to be exceedingly rare of men who can be said to be living before their age, and to be the repository of knowledge quite foreign to the thought of the time. The rule is that a number of persons are employed at a particular piece of work, but one being a few steps in advance of the others is able to crown the edifice with his name, or, having the ability to generalise already known facts, may become in time to be regarded as their originator. Therefore it is that one name is remembered whilst those of coequals have long been buried in obscurity.

Being in love with the one parent and hating the other are among the essential constituents of the stock of psychical impulses which is formed at that time and which is of such importance in determining the symptoms of the later neurosis... This discovery is confirmed by a legend that has come down to us from classical antiquity: a legend whose profound and universal power to move can only be understood if the hypothesis I have put forward in regard to the psychology of children has an equally universal validity. What I have in mind is the legend of King Oedipus and Sophocles' drama which bears his name.

Brutes by their natural instinct have produced many discoveries, whereas men by discussion and the conclusions of reason have given birth to few or none.

But in practical affairs, particularly in politics, men are needed who combine human experience and interest in human relations with a knowledge of science and technology. Moreover, they must be men of action and not contemplation. I have the impression that no method of education can produce people with all the qualities required. I am haunted by the idea that this break in human civilization, caused by the discovery of the scientific method, may be irreparable.

But it is just this characteristic of simplicity in the laws of nature hitherto discovered which it would be fallacious to generalize, for it is obvious that simplicity has been a part cause of their discovery, and can, therefore, give no ground for the supposition that other undiscovered laws are equally simple.

But just as astronomy succeeded astrology, following Kepler's discovery of planetary regularities, the discoveries of these many principles in empirical explorations of intellectual processes in machines should lead to a science, eventually.
[Co-author with South African mathematician, Seymour Papert (1928- )]

But medicine has long had all its means to hand, and has discovered both a principle and a method, through which the discoveries made during a long period are many and excellent, while full discovery will be made, if the inquirer be competent, conduct his researches with knowledge of the discoveries already made, and make them his starting-point. But anyone who, casting aside and rejecting all these means, attempts to conduct research in any other way or after another fashion, and asserts that he has found out anything, is and has been victim of deception.

But neither thirty years, nor thirty centuries, affect the clearness, or the charm, of Geometrical truths. Such a theorem as “the square of the hypotenuse of a right-angled triangle is equal to the sum of the squares of the sides” is as dazzlingly beautiful now as it was in the day when Pythagoras first discovered it, and celebrated its advent, it is said, by sacrificing a hecatomb of oxen—a method of doing honour to Science that has always seemed to me slightly exaggerated and uncalled-for. One can imagine oneself, even in these degenerate days, marking the epoch of some brilliant scientific discovery by inviting a convivial friend or two, to join one in a beefsteak and a bottle of wine. But a hecatomb of oxen! It would produce a quite inconvenient supply of beef.

But nothing of a nature foreign to the duties of my profession [clergyman] engaged my attention while I was at Leeds so much as the, prosecution of my experiments relating to electricity, and especially the doctrine of air. The last I was led into a consequence of inhabiting a house adjoining to a public brewery, where first amused myself with making experiments on fixed air [carbon dioxide] which found ready made in the process of fermentation. When I removed from that house, I was under the necessity making the fixed air for myself; and one experiment leading to another, as I have distinctly and faithfully noted in my various publications on the subject, I by degrees contrived a convenient apparatus for the purpose, but of the cheapest kind. When I began these experiments I knew very little of chemistry, and had in a manner no idea on the subject before I attended a course of chymical lectures delivered in the Academy at Warrington by Dr. Turner of Liverpool. But I have often thought that upon the whole, this circumstance was no disadvantage to me; as in this situation I was led to devise an apparatus and processes of my own, adapted to my peculiar views. Whereas, if I had been previously accustomed to the usual chemical processes, I should not have so easily thought of any other; and without new modes of operation I should hardly have discovered anything materially new.

But why, it has been asked, did you go there [the Antarctic]? Of what use to civilization can this lifeless continent be? ... [Earlier] expeditions contributed something to the accumulating knowledge of the Antarctic ... that helps us thrust back further the physical and spiritual shadows enfolding our terrestrial existence. Is it not true that one of the strongest and most continuously sustained impulses working in civilization is that which leads to discovery? As long as any part of the world remains obscure, the curiosity of man must draw him there, as the lodestone draws the mariner's needle, until he comprehends its secret.

But, contrary to the lady’s prejudices about the engineering profession, the fact is that quite some time ago the tables were turned between theory and applications in the physical sciences. Since World War II the discoveries that have changed the world are not made so much in lofty halls of theoretical physics as in the less-noticed labs of engineering and experimental physics. The roles of pure and applied science have been reversed; they are no longer what they were in the golden age of physics, in the age of Einstein, Schrödinger, Fermi and Dirac.

By and large it is uniformly true in mathematics that there is a time lapse between a mathematical discovery and the moment when it is useful; and that this lapse of time can be anything from 30 to 100 years, in some cases even more.