[The chemical bond] First, it is related to the disposition of two electrons (remember, no one has ever seen an electron!): next, these electrons have their spins pointing in opposite directions (remember, no one can ever measure the spin of a particular electron!): then, the spatial distribution of these electrons is described analytically with some degree of precision (remember, there is no way of distinguishing experimentally the density distribution of one electron from another!): concepts like hybridization, covalent and ionic structures, resonance, all appear, not one of which corresponds to anything that is directly measurable. These concepts make a chemical bond seem so real, so life-like, that I can almost see it. Then I wake with a shock to the realization that a chemical bond does not exist; it is a figment of the imagination that we have invented, and no more real than the square root of - 1. I will not say that the known is explained in terms of the unknown, for that is to misconstrue the sense of intellectual adventure. There is no explanation: there is form: there is structure: there is symmetry: there is growth: and there is therefore change and life.

Any one whose disposition leads him to attach more weight to unexplained difficulties than to the explanation of facts will certainly reject my theory.

As geologists, we learn that it is not only the present condition of the globe that has been suited to the accommodation of myriads of living creatures, but that many former states also have been equally adapted to the organization and habits of prior races of beings. The disposition of the seas, continents, and islands, and the climates have varied; so it appears that the species have been changed, and yet they have all been so modelled, on types analogous to those of existing plants and animals, as to indicate throughout a perfect harmony of design and unity of purpose. To assume that the evidence of the beginning or end of so vast a scheme lies within the reach of our philosophical inquiries, or even of our speculations, appears to us inconsistent with a just estimate of the relations which subsist between the finite powers of man and the attributes of an Infinite and Eternal Being.

As regards religion, on the other hand, one is generally agreed that it deals with goals and evaluations and, in general, with the emotional foundation of human thinking and acting, as far as these are not predetermined by the inalterable hereditary disposition of the human species. Religion is concerned with man’s attitude toward nature at large, with the establishing of ideals for the individual and communal life, and with mutual human relationship. These ideals religion attempts to attain by exerting an educational influence on tradition and through the development and promulgation of certain easily accessible thoughts and narratives (epics and myths) which are apt to influence evaluation and action along the lines of the accepted ideals.

But here it may be objected, that the present Earth looks like a heap of Rubbish and Ruines; And that there are no greater examples of confusion in Nature than Mountains singly or jointly considered; and that there appear not the least footsteps of any Art or Counsel either in the Figure and Shape, or Order and Disposition of Mountains and Rocks. Wherefore it is not likely they came so out of God's hands ... To which I answer, That the present face of the Earth with all its Mountains and Hills, its Promontaries and Rocks, as rude and deformed as they appear, seems to me a very beautiful and pleasant object, and with all the variety of Hills, and Valleys, and Inequalities far more grateful to behold, than a perfectly level Countrey without any rising or protuberancy, to terminate the sight: As anyone that hath but seen the Isle of Ely, or any the like Countrey must need acknowledge.

But in nothing are swifts more singular than in their early retreat. They retire, as to the main body of them, by the tenth of August, and sometimes a few days sooner: and every straggler invariably withdraws by the twentieth, while their congeners, all of them, stay till the beginning of October; many of them all through that month, and some occasionally to the beginning of November. This early retreat is mysterious and wonderful, since that time is often the sweetest season in the year. But, what is more extraordinary, they begin to retire still earlier in the most southerly parts of Andalusia, where they can be no ways influenced by any defect of heat; or, as one might suppose, defect of food. Are they regulated in their motions with us by failure of food, or by a propensity to moulting, or by a disposition to rest after so rapid a life, or by what? This is one of those incidents in natural history that not only baffles our searches, but almost eludes our guesses!

Even the mind depends so much on temperament and the disposition of one’s bodily organs that, if it is possible to find a way to make people generally more wise and more skilful than they have been in the past, I believe that we should look for it in medicine. It is true that medicine as it is currently practiced contains little of much use.

For myself, I found that I was fitted for nothing so well as for the study of Truth; as having a mind nimble and versatile enough to catch the resemblances of things (which is the chief point) , and at the same time steady enough to fix and distinguish their subtler differences; as being gifted by nature with desire to seek, patience to doubt, fondness to meditate, slowness to assert, readiness to reconsider, carefulness to dispose and set in order; and as being a man that neither affects what is new nor admires what is old, and that hates every kind of imposture. So I thought my nature had a kind of familiarity and relationship with Truth.

I have a friendly feeling towards pigs generally, and consider them the most intelligent of beasts, not excepting the elephant and the anthropoid ape—the dog is not to be mentioned in this connection. I also like his disposition and attitude towards all other creatures, especially man. He is not suspicious, or shrinkingly submissive, like horses, cattle, and sheep; nor an impudent devil-may-care like the goat; nor hostile like the goose; nor condescending like the cat; nor a flattering parasite like the dog. He views us from a totally different, a sort of democratic, standpoint as fellow-citizens and brothers, and takes it for granted, or grunted, that we understand his language, and without servility or insolence he has a natural, pleasant, camerados-all or hail-fellow-well-met air with us.

I have been scientifically studying the traits and dispositions of the “lower animals” (so-called,) and contrasting them with the traits and dispositions of man. I find the result profoundly humiliating to me. For it obliges me to renounce my allegiance to the Darwinian theory of the Ascent of Man from the Lower Animals; since it now seems plain to me that that theory ought to be vacated in favor of a new and truer one, this new and truer one to be named the Descent of Man from the Higher Animals.

I shall conclude, for the time being, by saying that until Philosophers make observations (especially of mountains) that are longer, more attentive, orderly, and interconnected, and while they fail to recognize the two great agents, fire and water, in their distinct affects, they will not be able to understand the causes of the great natural variety in the disposition, structure, and other matter that can be observed in the terrestrial globe in a manner that truly corresponds to the facts and to the phenomena of Nature.

I specifically paused to show that, if there were such machines with the organs and shape of a monkey or of some other non-rational animal, we would have no way of discovering that they are not the same as these animals. But if there were machines that resembled our bodies and if they imitated our actions as much as is morally possible, we would always have two very certain means for recognizing that, none the less, they are not genuinely human. The first is that they would never be able to use speech, or other signs composed by themselves, as we do to express our thoughts to others. For one could easily conceive of a machine that is made in such a way that it utters words, and even that it would utter some words in response to physical actions that cause a change in its organs—for example, if someone touched it in a particular place, it would ask what one wishes to say to it, or if it were touched somewhere else, it would cry out that it was being hurt, and so on. But it could not arrange words in different ways to reply to the meaning of everything that is said in its presence, as even the most unintelligent human beings can do. The second means is that, even if they did many things as well as or, possibly, better than anyone of us, they would infallibly fail in others. Thus one would discover that they did not act on the basis of knowledge, but merely as a result of the disposition of their organs. For whereas reason is a universal instrument that can be used in all kinds of situations, these organs need a specific disposition for every particular action.

In attempting to explain geological phenomena, the bias has always been on the wrong side; there has always been a disposition to reason á priori on the extraordinary violence and suddenness of changes, both in the inorganic crust of the earth, and in organic types, instead of attempting strenuously to frame theories in accordance with the ordinary operations of nature.

In scientific study, or, as I prefer to phrase it, in creative scholarship, the truth is the single end sought; all yields to that. The truth is supreme, not only in the vague mystical sense in which that expression has come to be a platitude, but in a special, definite, concrete sense. Facts and the immediate and necessary inductions from facts displace all pre-conceptions, all deductions from general principles, all favourite theories. Previous mental constructions are bowled over as childish play-structures by facts as they come rolling into the mind. The dearest doctrines, the most fascinating hypotheses, the most cherished creations of the reason and of the imagination perish from a mind thoroughly inspired with the scientific spirit in the presence of incompatible facts. Previous intellectual affections are crushed without hesitation and without remorse. Facts are placed before reasonings and before ideals, even though the reasonings and the ideals be more beautiful, be seemingly more lofty, be seemingly better, be seemingly truer. The seemingly absurd and the seemingly impossible are sometimes true. The scientific disposition is to accept facts upon evidence, however absurd they may appear to our pre-conceptions.

In the year 1902 (while I was attempting to explain to an elementary class in chemistry some of the ideas involved in the periodic law) becoming interested in the new theory of the electron, and combining this idea with those which are implied in the periodic classification, I formed an idea of the inner structure of the atom which, although it contained certain crudities, I have ever since regarded as representing essentially the arrangement of electrons in the atom ... In accordance with the idea of Mendeleef, that hydrogen is the first member of a full period, I erroneously assumed helium to have a shell of eight electrons. Regarding the disposition in the positive charge which balanced the electrons in the neutral atom, my ideas were very vague; I believed I inclined at that time toward the idea that the positive charge was also made up of discrete particles, the localization of which determined the localization of the electrons.

It goes so heavily with my disposition that this goodly frame, the earth, seems to me a sterile promontory. This most excellent canopy the air, look you, this brave o'erhanging, this majestic roof fretted with golden fire—why, it appears no other thing to me than a foul and pestilent congregation of vapours. What a piece of work is a man. How noble in reason, how infinite in faculty, in form and moving, how express and admirable, in action, how like an angel! in apprehension, how like a god—the beauty of the world, the paragon of animals! And yet to me, what is this quintessence of dust? Man delights not me—no, nor woman neither, though by your smiling you seem to say so.

It is necessary that a surgeon should have a temperate and moderate disposition. That he should have well-formed hands, long slender fingers, a strong body, not inclined to tremble and with all his members trained to the capable fulfilment of the wishes of his mind. He should be of deep intelligence and of a simple, humble, brave, but not audacious disposition. He should be well grounded in natural science, and should know not only medicine but every part of philosophy; should know logic well, so as to be able to understand what is written, to talk properly, and to support what he has to say by good reasons.

It would be a mistake to suppose that a science consists entirely of strictly proved theses, and it would be unjust to require this. Only a disposition with a passion for authority will raise such a demand, someone with a craving to replace his religious catechism by another, though it is a scientific one. Science has only a few apodeictic propositions in its catechism: the rest are assertions promoted by it to some particular degree of probability. It is actually a sign of a scientific mode of thought to find satisfaction in these approximations to certainty and to be able to pursue constructive work further in spite of the absence of final confirmation.

Nothing has more retarded the advancement of learning than the disposition of vulgar minds to ridicule and vilify what they cannot comprehend.

Nothing has tended more to retard the advancement of science than the disposition in vulgar minds to vilify what they cannot comprehend.

Now when naturalists observe a close agreement in numerous small details of habits, tastes, and dispositions between two or more domestic races, or between nearly-allied natural forms, they use this fact as an argument that they are descended from a common progenitor who was thus endowed; and consequently that all should be classed under the same species. The same argument may be applied with much force to the races of man.

Take away these instinctive dispositions with their powerful impulses, and the organism would become incapable of activity of any kind; it would lie inert and motionless like a wonderful clockwork whose mainspring had been removed or a steam-engine whose fires had been withdrawn.

The doctrine called Philosophical Necessity is simply this: that, given the motives which are present to an individual’s mind, and given likewise the character and disposition of the individual, the manner in which he will act might be unerringly inferred: that if we knew the person thoroughly, and knew all the inducements which are acting upon him, we could foretell his conduct with as much certainty as we can predict any physical event.

The fact is, a biologist to-day [1928] is pretty much where an engineer would be if he knew even in detail the cycle of chemical changes which took place within an internal combustion engine but was wholly ignorant of the disposition of tho moving parts.

The general disposition of the land [in the Periodic Kingdom] is one of metals in the west, giving way, as you travel eastward, to a varied landscape of nonmetals, which terminates in largely inert elements at the eastern shoreline. To the south of the mainland, there is an offshore island, which we shall call the Southern Island. It consists entirely of metals of subtly modulated personality. North of the mainland, situated rather like Iceland off the northwestern edge of Europe, lies a single, isolated region-hydrogen. This simple but gifted element is an essential outpost of the kingdom, for despite its simplicity it is rich in chemical personality. It is also the most abundant element in the universe and the fuel of the stars.

The outlook seems grim. Natural selection under civilized conditions may lead mankind to evolve towards a state of genetic overspecialization for living in gadget-ridden environments. It is certainly up to man to decide whether this direction of his evolution is or is not desirable. If it is not, man has, or soon will have, the knowledge requisite to redirect the evolution of his species pretty much as he sees fit. Perhaps we should not be too dogmatic about this choice of direction. We may be awfully soft compared to paleolithic men when it comes to struggling, unaided by gadgets, with climatic difficulties and wild beasts. Most of us feel most of the time that this is not a very great loss. If our remote descendants grow to be even more effete than we are, they may conceivably be compensated by acquiring genotypes conducive to kindlier dispositions and greater intellectual capacities than those prevalent in mankind today.
[Co-author with American statistician Gordon Allen.]

The sciences are of a sociable disposition, and flourish best in the neighborhood of each other; nor is there any branch of learning but may be helped and improved by assistance drawn from other arts.

The theory of the method of knowing which is advanced in these pages may be termed pragmatic. ... Only that which has been organized into our disposition so as to enable us to adapt the environment to our needs and adapt our aims and desires to the situation in which we live is really knowledge.

There are still many unsolved problems about bird life, among which are the age that birds attain, the exact time at which some birds acquire their adult dress, and the changes which occur in this with years. Little, too, is known about the laws and routes of bird migration, and much less about the final disposition of the untold thousands which are annually produced.

There cannot be design without a designer; contrivance without a contriver; order without choice; arrangement, without any thing capable of arranging; subserviency and relation to a purpose; means suitable to an end, and executing their office in accomplishing that end, without the end ever having been contemplated, or the means accommodated to it. Arrangement, disposition of parts, subserviency of means to an end, relation of instruments to use, imply the preference of intelligence and mind.

There is no short cut, nor “royal road” to the attainment of medical knowledge. The path which we have to pursue is long, difficult, and unsafe. In our progress, we must frequently take up our abode with death and corruption, we must adopt loathsome diseases for our familiar associates, or we shall never be acquainted with their nature and dispositions ; we must risk, nay, even injure our own health, in order to be able to preserve, or restore that of others.

This is the excellent foppery of the world: that when we are sick in fortune—often the surfeits of our own behaviour—we make guilty of our disasters the sun, the moon, and stars, as if we were villains on necessity, fools by heavenly compulsion, knaves, thieves, and treachers by spherical predominance, drunkards, liars, and adulterers, by an enforced obedience of planetary influence, and all that we are evil in, by a divine thrusting on. An admirable evasion of whoremaster man, to lay his goatish disposition on the charge of a star! My father compounded with my mother under the Dragon's tail and my nativity was under Ursa Major, so that it follows that I am rough and lecherous. Fut! I should have been that I am had the maidenliest star in the firmament twinkled on my bastardizing.

Those who have occasion to enter into the depths of what is oddly, if generously, called the literature of a scientific subject, alone know the difficulty of emerging with an unsoured disposition. The multitudinous facts presented by each corner of Nature form in large part the scientific man's burden to-day, and restrict him more and more, willy-nilly, to a narrower and narrower specialism. But that is not the whole of his burden. Much that he is forced to read consists of records of defective experiments, confused statement of results, wearisome description of detail, and unnecessarily protracted discussion of unnecessary hypotheses. The publication of such matter is a serious injury to the man of science; it absorbs the scanty funds of his libraries, and steals away his poor hours of leisure.

To a man of an impatient disposition, like James Gray, it became clear that in view of the very large number of known species many more generations of scientists could be kept occupied as sedate, taxonomic filing clerks by painstaking description and comparison of structures. This sort of existence was not for him; it lacked the excitement of discovery, and was not likely to make the principles or mechanisms underlying the process of evolution any more plausible.

To judge in this [utilitarian] way demonstrates … how small, narrow and indolent our minds are; it shows a disposition always to calculate the reward before the work, a cold heart and a lack of feeling for everything that is great and honours mankind. Unfortunately one cannot deny that such a mode of thinking is common in our age, and I am convinced that this is closely connected with the catastrophes which have befallen many countries in recent times; do not mistake me, I do not talk of the general lack of concern for science, but of the source from which all this has come, of the tendency to look out everywhere for one’s advantage and to relate everything to one’s physical well being, of indifference towards great ideas, of aversion to any effort which derives from pure enthusiasm.

Understanding a theory has, indeed, much in common with understanding a human personality. We may know or understand a man's system of dispositions pretty well; that is to say, we may be able to predict how he would act in a number of different situations. But since there are infinitely many possible situations, of infinite variety, a full understanding of a man's dispositions does not seem to be possible.

We are once for all adapted to the military status. A millennium of peace would not breed the fighting disposition out of our bone and marrow, and a function so ingrained and vital will never consent to die without resistance, and will always find impassioned apologists and idealizers.

We know next to nothing about virtually everything. It is not necessary to know the origin of the universe; it is necessary to want to know. Civilization depends not on any particular knowledge, but on the disposition to crave knowledge

We must remain, in a word, in an intellectual disposition which seems paradoxical, but which, in my opinion, represents the true mind of the investigator. We must have a robust faith and yet not believe.
[Often seen summarized as: The investigator should have a robust faith—and yet not believe.]

What I chiefly admired, and thought altogether unaccountable, was the strong disposition I observed in them [the mathematicians of Laputa] towards news and politics; perpetually inquiring into public affairs; giving their judgments in matters of state; and passionately disputing every inch of party opinion. I have indeed observed the same disposition among most of the mathematicians I have known in Europe, although I could never discover the least analogy between the two sciences.

Whoever is to acquire a competent knowledge of medicine, ought to be possessed of the following advantages: a natural disposition; instructionl a favorable place for the study; early tuition, love of labor; leisure.

Will power is only the tensile strength of one’s own disposition. One cannot increase it by a single ounce.

Women have absolutely no sense of art, though they may have of poetry. They have no natural disposition for the sciences, though they may have for philosophy. They are by no means wanting in power of speculation and intuitive perception of the infinite; they lack only power of abstraction, which is far more easy to be learned.

You will be astonished to find how the whole mental disposition of your children changes with advancing years. A young child and the same when nearly grown, sometimes differ almost as much as do a caterpillar and butterfly.