…it ought to be remembered that there is nothing more difficult to take in hand, more perilous to conduct, or more uncertain in its success, than to take the lead in the introduction of a new order of things. Because the innovator has for enemies all those who have done well under the old conditions, and lukewarm defenders in those who may do well under the new.

[On the propulsive force of rockets] One part of fire takes up as much space as ten parts of air, and one part of air takes up the space of ten parts of water, and one part of water as much as ten parts of earth. Now powder is earth, consisting of the four elementary principles, and when the sulfur conducts the fire into the dryest part of the powder, fire, and air increase … the other elements also gird themselves for battle with each other and the rage of battle is changed by their heat and moisture into a strong wind.

Die nicht wãsserigen Losungen leiten ja nicht.
Non-aqueous solutions don't conduct.

In primis, hominis est propria VERI inquisitio atque investigato. Itaque cum sumus negotiis necessariis, curisque vacui, tum avemus aliquid videre, audire, ac dicere, cognitionemque rerum, aut occultarum aut admirabilium, ad benè beatéque vivendum necessariam ducimus; —ex quo intelligitur, quod VERUM, simplex, sincerumque sit, id esse naturæ hominis aptissimum. Huic veri videndi cupiditati adjuncta est appetitio quædam principatûs, ut nemini parere animus benè a naturâ informatus velit, nisi præcipienti, aut docenti, aut utilitatis causâ justè et legitimè imperanti: ex quo animi magnitudo existit, et humanarum rerum contemtio.
Before all other things, man is distinguished by his pursuit and investigation of TRUTH. And hence, when free from needful business and cares, we delight to see, to hear, and to communicate, and consider a knowledge of many admirable and abstruse things necessary to the good conduct and happiness of our lives: whence it is clear that whatsoever is TRUE, simple, and direct, the same is most congenial to our nature as men. Closely allied with this earnest longing to see and know the truth, is a kind of dignified and princely sentiment which forbids a mind, naturally well constituted, to submit its faculties to any but those who announce it in precept or in doctrine, or to yield obedience to any orders but such as are at once just, lawful, and founded on utility. From this source spring greatness of mind and contempt of worldly advantages and troubles.

A statistical analysis, properly conducted, is a delicate dissection of uncertainties, a surgery of suppositions.

But medicine has long had all its means to hand, and has discovered both a principle and a method, through which the discoveries made during a long period are many and excellent, while full discovery will be made, if the inquirer be competent, conduct his researches with knowledge of the discoveries already made, and make them his starting-point. But anyone who, casting aside and rejecting all these means, attempts to conduct research in any other way or after another fashion, and asserts that he has found out anything, is and has been victim of deception.

Chemical research conducts to the knowledge of philosophical truth, and forms the mind to philosophical enlargement and accuracy of thought, more happily than almost any other species of investigation in which the human intellect can be employed.

Chemists have made of phlogiston a vague principle which is not at all rigorously defined, and which, in consequence, adapts itself to all explanations in which it is wished it shall enter; sometimes it is free fire, sometimes it is fire combined with the earthy element; sometimes it passes through the pores of vessels, sometimes they are impenetrable to it; it explains both the causticity and non-causticity, transparency and opacity, colours and absence of colours. It is a veritable Proteus which changes its form every instant. It is time to conduct chemistry to a more rigorous mode of reasoning ... to distinguish fact and observation from what is systematic and hypothetical.

Could the young but realize how soon they will become mere walking bundles of habits, they would give more heed to their conduct while in the plastic state. We are spinning our own fates, good or evil, and never to be undone.

CREATION OF LIFE.
The Startling Discovery of Prof. Loeb.
Lower Animals Produced by Chemical Means.
Process May Apply to the Human Species.
Immaculate Conception is Explained.
Wonderful Experiments Conducted at Woods Hole.

Doctors and Clergymen. A physician’s physiology has much the same relation to his power of healing as a cleric’s divinity has to his power of influencing conduct.

Even a wise experiment when made by a fool generally leads to a false conclusion, but that fools’ experiments conducted by a genius often prove to be leaps through the dark into great discoveries.

He who made us would have been a pitiful bungler if he had made the rules of our moral conduct a matter of science. For one man of science, there are thousands who are not. … State a moral case to a ploughman and a professor. The former will decide it as well, and often better than the latter, because he has not been led astray by artificial rules.

Here is the element or power of conduct, of intellect and knowledge, of beauty, and of social life and manners, and all needful to build up a complete human life. … We have instincts responding to them all, and requiring them all, and we are perfectly civilized only when all these instincts of our nature—all these elements in our civilization have been adequately recognized and satisfied.

I do not forget that Medicine and Veterinary practice are foreign to me. I desire judgment and criticism upon all my contributions. Little tolerant of frivolous or prejudiced contradiction, contemptuous of that ignorant criticism which doubts on principle, I welcome with open arms the militant attack which has a method of doubting and whose rule of conduct has the motto “More light.”

I have always attached great importance to the manner in which an experiment is set up and conducted ... the experiment should be set up to open as many windows as possible on the unforeseen.

I have been battering away at Saturn, returning to the charge every now and then. I have effected several breaches in the solid ring, and now I am splash into the fluid one, amid a clash of symbols truly astounding. When I reappear it will be in the dusky ring, which is something like the state of the air supposing the siege of Sebastopol conducted from a forest of guns 100 miles one way, and 30,000 miles the other, and the shot never to stop, but go spinning away round a circle, radius 170,000 miles.

I never allow myself to become discouraged under any circumstances. … After we had conducted thousands of experiments on a certain project without solving the problem, … we had learned something. For we had learned for a certainty that the thing couldn’t be done that way, and that we would have to try some other way. We sometimes learn a lot from our failures if we have put into the effort the best thought and work we are capable of.

I wanted some new names to express my facts in Electrical science without involving more theory than I could help & applied to a friend Dr Nicholl [his doctor], who has given me some that I intend to adopt for instance, a body decomposable by the passage of the Electric current, I call an ‘electrolyte’ and instead of saying that water is electro chemically decomposed I say it is ‘electrolyzed’. The intensity above which a body is decomposed beneath which it conducts without decomposition I call the ‘Electrolyte intensity’ &c &c. What have been called: the poles of the battery I call the electrodes they are not merely surfaces of metal, but even of water & air, to which the term poles could hardly apply without receiving a new sense. Electrolytes must consist of two parts which during the electrolization, are determined the one in the one direction, and the other towards the poles where they are evolved; these evolved substances I call zetodes, which are therefore the direct constituents of electrolites.

I wish that one would be persuaded that psychological experiments, especially those on the complex functions, are not improved [by large studies]; the statistical method gives only mediocre results; some recent examples demonstrate that. The American authors, who love to do things big, often publish experiments that have been conducted on hundreds and thousands of people; they instinctively obey the prejudice that the persuasiveness of a work is proportional to the number of observations. This is only an illusion.

If it were possible for us to have so deep an insight into a man's character as shown both in inner and in outer actions, that every, even the least, incentive to these actions and all external occasions which affect them were so known to us that his future conduct could be predicted with as great a certainty as the occurrence of a solar or lunar eclipse, we could nevertheless still assert that the man is free.

If the Commission is to enquire into the conditions “to be observed,” it is to be presumed that they will give the result of their enquiries; or, in other words, that they will lay down, or at least suggest, “rules” and “conditions to be (hereafter) observed” in the construction of bridges, or, in other words, embarrass and shackle the progress of improvement to-morrow by recording and registering as law the prejudices or errors of to-day.
[Objecting to any interference by the State with the freedom of civil engineers in the conduct of their professional work.]

If you ask ... the man in the street ... the human significance of mathematics, the answer of the world will be, that mathematics has given mankind a metrical and computatory art essential to the effective conduct of daily life, that mathematics admits of countless applications in engineering and the natural sciences, and finally that mathematics is a most excellent instrumentality for giving mental discipline... [A mathematician will add] that mathematics is the exact science, the science of exact thought or of rigorous thinking.

In 1847 I gave an address at Newton, Mass., before a Teachers’ Institute conducted by Horace Mann. My subject was grasshoppers. I passed around a large jar of these insects, and made every teacher take one and hold it while I was speaking. If any one dropped the insect, I stopped till he picked it up. This was at that time a great innovation, and excited much laughter and derision. There can be no true progress in the teaching of natural science until such methods become general.

In acute diseases the physician must conduct his inquiries in the following way. First he must examine the face of the patient, and see whether it is like the faces of healthy people, and especially whether it is like its usual self. Such likeness will be the best sign, and the greatest unlikeness will be the most dangerous sign. The latter will be as follows. Nose sharp, eyes hollow, temples sunken, ears cold and contracted with their lobes turned outwards, the skin about the face hard and tense and parched, the colour of the face as a whole being yellow or black.

In an objective system … any mingling of knowledge with values is unlawful, forbidden. But [the] … “first commandment” which ensures the foundation of objective knowledge, is not itself objective. It cannot be objective: it is an ethical guideline, a rule for conduct. True knowledge is ignorant of values, but it cannot be grounded elsewhere than upon a value judgment…

In France, where an attempt has been made to deprive me of the originality of these discoveries, experiments without number and without mercy have been made on living animals; not under the direction of anatomical knowledge, or the guidance of just induction, but conducted with cruelty and indifference, in hope to catch at some of the accidental facts of a system, which, is evident, the experimenters did not fully comprehend.

It would seem at first sight as if the rapid expansion of the region of mathematics must be a source of danger to its future progress. Not only does the area widen but the subjects of study increase rapidly in number, and the work of the mathematician tends to become more and more specialized. It is, of course, merely a brilliant exaggeration to say that no mathematician is able to understand the work of any other mathematician, but it is certainly true that it is daily becoming more and more difficult for a mathematician to keep himself acquainted, even in a general way, with the progress of any of the branches of mathematics except those which form the field of his own labours. I believe, however, that the increasing extent of the territory of mathematics will always be counteracted by increased facilities in the means of communication. Additional knowledge opens to us new principles and methods which may conduct us with the greatest ease to results which previously were most difficult of access; and improvements in notation may exercise the most powerful effects both in the simplification and accessibility of a subject. It rests with the worker in mathematics not only to explore new truths, but to devise the language by which they may be discovered and expressed; and the genius of a great mathematician displays itself no less in the notation he invents for deciphering his subject than in the results attained. … I have great faith in the power of well-chosen notation to simplify complicated theories and to bring remote ones near and I think it is safe to predict that the increased knowledge of principles and the resulting improvements in the symbolic language of mathematics will always enable us to grapple satisfactorily with the difficulties arising from the mere extent of the subject.

Learning acquired in youth arrests the evil of old age; and if you understand that old age has wisdom for its food, you will so conduct yourself in youth that your old age will not lack for nourishment.

Leo Szilard’s Ten Commandments:
1. Recognize the connections of things and the laws of conduct of men, so that you may know what you are doing.
2. Let your acts be directed towards a worthy goal, but do not ask if they will reach it; they are to be models and examples, not means to an end.
3. Speak to all men as you do to yourself, with no concern for the effect you make, so that you do not shut them out from your world; lest in isolation the meaning of life slips out of sight and you lose the belief in the perfection of the creation.
4. Do not destroy what you cannot create.
5. Touch no dish, except that you are hungry.
6. Do not covet what you cannot have.
7. Do not lie without need.
8. Honor children. Listen reverently to their words and speak to them with infinite love.
9. Do your work for six years; but in the seventh, go into solitude or among strangers, so that the memory of your friends does not hinder you from being what you have become.
10. Lead your life with a gentle hand and be ready to leave whenever you are called.

Logic does not pretend to teach the surgeon what are the symptoms which indicate a violent death. This he must learn from his own experience and observation, or from that of others, his predecessors in his peculiar science. But logic sits in judgment on the sufficiency of that observation and experience to justify his rules, and on the sufficiency of his rules to justify his conduct. It does not give him proofs, but teaches him what makes them proofs, and how he is to judge of them.

Man is no new-begot child of the ape, bred of a struggle for existence upon brutish lines—nor should the belief that such is his origin, oft dinned into his ears by scientists, influence his conduct. Were he to regard himself as an extremely ancient type, distinguished chiefly by the qualities of his mind, and to look upon the existing Primates as the failures of his line, as his misguided and brutish collaterals, rather than as his ancestors, I think it would be something gained for the ethical outlook of Homo—and also it would be consistent with present knowledge.

Not to teach a class, but to conduct it: I punch the tickets and call out the stops along the way.

Occurrences that other men would have noted only with the most casual interest became for Whitney exciting opportunities to experiment. Once he became disturbed by a scientist's seemingly endless pursuit of irrelevant details in the course of an experiment, and criticized this as being as pointless as grabbing beans out of a pot, recording the numbers, and then analyzing the results. Later that day, after he had gone home, his simile began to intrigue him, and he asked himself whether it would really be pointless to count beans gathered in such a random manner. Another man might well have dismissed this as an idle fancy, but to Whitney an opportunity to conduct an experiment was not to be overlooked. Accordingly, he set a pot of beans beside his bed, and for several days each night before retiring he would take as many beans as he could grasp in one hand and make a note of how many were in the handful. After several days had passed he was intrigued to find that the results were not as unrewarding as he had expected. He found that each handful contained more beans than the one before, indicating that with practice he was learning to grasp more and more beans. “This might be called research in morphology, the science of animal structure,” he mused. “My hand was becoming webbed … so I said to myself: never label a real experiment useless, it may reveal something unthought of but worth knowing.”

One wonders whether the rare ability to be completely attentive to, and to profit by, Nature’s slightest deviation from the conduct expected of her is not the secret of the best research minds and one that explains why some men turn to most remarkably good advantage seemingly trivial accidents. Behind such attention lies an unremitting sensitivity.

Plant breeding to be successful must be conducted like architecture. Definite plans must be carefully laid for the proposed creation; suitable materials selected with judgment, and these must he securely placed in their proper order and position.

Psychoanalysis is a science conducted by lunatics for lunatics. They are generally concerned with proving that people are irresponsible; and they certainly succeed in proving that some people are.

Psychologists must cease to be content with the sterile and narrow conception of their science as the science of consciousness, and must boldly assert its claim to be the positive science of mind in all its aspects and modes of functining, or, as I would prefer to say, the positive science of conduct or behavior.

Reason must approach nature with the view, indeed, of receiving information from it, not, however, in the character of a pupil, who listens to all that his master chooses to tell him, but in that of a judge, who compels the witnesses to reply to those questions which he himself thinks fit to propose. To this single idea must the revolution be ascribed, by which, after groping in the dark for so many centuries, natural science was at length conducted into the path of certain progress.

Science conducts us, step by step, through the whole range of creation, until we arrive, at length, at God.

Science is the search for truth. It is not a game in which one tries to beat his opponent, to do harm to others. We need to have the spirit of science in international affairs, to make the conduct of international affairs the effort to find the right solution, the just solution of international problems, not the effort by each nation to get the better of other nations, to do harm to them when it is possible.

Scientists today … have to be able to interpret their findings just as skillfully as they conduct their research. If not, a lot of priceless new knowledge will have to wait for a better man.

The ‘Doctrine of Uniformity’ in Geology, as held by many of the most eminent of British Geologists, assumes that the earth’s surface and upper crust have been nearly as they are at present in temperature, and other physical qualities, during millions of millions of years. But the heat which we know, by observation, to be now conducted out of the earth yearly is so great, that if this action has been going on with any approach to uniformity for 20,000 million years, the amount of heat lost out of the earth would have been about as much as would heat, by 100 Cent., a quantity of ordinary surface rock of 100 times the earth’s bulk. This would be more than enough to melt a mass of surface rock equal in bulk to the whole earth. No hypothesis as to chemical action, internal fluidity, effects of pressure at great depth, or possible character of substances in the interior of the earth, possessing the smallest vestige of probability, can justify the supposition that the earth’s upper crust has remained nearly as it is, while from the whole, or from any part, of the earth, so great a quantity of heat has been lost.

The astronomer may speak to you of his understanding of space, but he cannot give you his understanding. … And he who is versed in the science of numbers can tell of the regions of weight and measure, but he cannot conduct you thither.

The doctrine called Philosophical Necessity is simply this: that, given the motives which are present to an individual’s mind, and given likewise the character and disposition of the individual, the manner in which he will act might be unerringly inferred: that if we knew the person thoroughly, and knew all the inducements which are acting upon him, we could foretell his conduct with as much certainty as we can predict any physical event.

The external resistance may also be varied. For instance, let mercury or some other liquid form part of a voltaic circuit, then the more deeply the conducting wire is immersed in the mercury or other liquid the less resistance does the liquid offer to the passage of the current Hence the vibration of the conducting wire in mercury or other liquid included in the circuit occasions undulations in the current…

The fundamental characteristic of the scientific method is honesty. In dealing with any question, science asks no favors. ... I believe that constant use of the scientific method must in the end leave its impress upon him who uses it. ... A life spent in accordance with scientific teachings would be of a high order. It would practically conform to the teachings of the highest types of religion. The motives would be different, but so far as conduct is concerned the results would be practically identical.

The imagination is … the most precious faculty with which a scientist can be equipped. It is a risky possession, it is true, for it leads him astray a hundred times for once that it conducts him to truth; but without it he has no chance at all of getting at the meaning of the facts he has learned or discovered.

The love of science, and the energy and honesty in the pursuit of science, in the best of the Aryan races do seem to correspond in a remarkable way to the love of conduct, and the energy and honesty in the pursuit of conduct, in the best of the Semitic.

The most extensive computation known has been conducted over the last billion years on a planet-wide scale: it is the evolution of life. The power of this computation is illustrated by the complexity and beauty of its crowning achievement, the human brain.

The practice of that which is ethically best—what we call goodness or virtue—involves a course of conduct which, in all respects, is opposed to that which leads to success in the cosmic struggle for existence. In place of ruthless self-assertion it demands self-restraint; in place of thrusting aside, or treading down, all competitors, it requires that the individual shall not merely respect, but shall help his fellows… It repudiates the gladiatorial theory of existence… Laws and moral precepts are directed to the end of curbing the cosmic process.

The teaching of elementary mathematics should be conducted so that the way should be prepared for the building upon them of the higher mathematics. The teacher should always bear in mind and look forward to what is to come after. The pupil should not be taught what may be sufficient for the time, but will lead to difficulties in the future. … I think the fault in teaching arithmetic is that of not attending to general principles and teaching instead of particular rules. … I am inclined to attack Teaching of Mathematics on the grounds that it does not dwell sufficiently on a few general axiomatic principles.

The valuable properties of this cement depend in a great measure on the mode of preparing it for use. The mixing should therefore be conducted with care in order to form a perfect union of the powdered cement, sand and water. This can be best accomplished by the use of the New England corn hoe on a board floor or by beating with a hand stamper; not much labour is required if properly applied. Mechanics can judge when the mixture is perfect by the appearance of the mortar, which, when properly prepared, very much resembles putty.

There is no field of biological inquiry in which the influence of the Origin of Species is not traceable; the foremost men of science in every country are either avowed champions of its leading doctrines, or at any rate abstain from opposing them; a host of young and ardent investigators seek for and find inspiration and guidance in Mr. Darwin’s great work; and the general doctrine of Evolution, to one side of which it gives expression, finds in the phenomena of biology a firm base of operations whence it may conduct its conquest of the whole realm of nature.

These expert men, technologists, engineers, or whatever name may best suit them, make up the indispensable General staff of the industrial system; and without their immediate and unremitting guidance and correction the industrial system will not work. It is a mechanically organized structure of technical processes designed, installed, and conducted by these production engineers. Without them and their constant attention the industrial equipment, the mechanical appliances of industry, will foot up to just so much junk.

Though the parallel is not complete, it is safe to say that science will never touch them unaided by its practical applications. Its wonders may be catalogued for purposes of education, they may be illustrated by arresting experiments, by numbers and magnitudes which startle or fatigue the imagination but they will form no familiar portion of the intellectual furniture of ordinary men unless they be connected, however remotely, with the conduct of ordinary life.

Throughout his last half-dozen books, for example, Arthur Koestler has been conducting a campaign against his own misunderstanding of Darwinism. He hopes to find some ordering force, constraining evolution to certain directions and overriding the influence of natural selection ... Darwinism is not the theory of capricious change that Koestler imagines. Random variation may be the raw material of change, but natural selection builds good design by rejecting most variants while accepting and accumulating the few that improve adaptation to local environments.

To discover a Conception of the mind which will justly represent a train of observed facts is, in some measure, a process of conjecture, ... and the business of conjecture is commonly conducted by calling up before our minds several suppositions, selecting that one which most agrees with what we know of the observed facts. Hence he who has to discover the laws of nature may have to invent many suppositions before he hits upon the right one; and among the endowments which lead to his success, we must reckon that fertility of invention which ministers to him such imaginary schemes, till at last he finds the one which conforms to the true order of nature.

Truth and falsity, indeed understanding, is not necessarily something purely intellectual, remote from feelings and attitudes. ... It is in the total conduct of men rather than in their statements that truth or falsehood lives, more in what a man does, in his real reaction to other men and to things, in his will to do them justice, to live at one with them. Here lies the inner connection between truth and justice. In the realm of behavior and action, the problem recurs as to the difference between piece and part.

Water from clay pipes is much more wholesome than that which is conducted through lead pipes, because lead is found to be harmful for the reason that white lead is derived from it, and this is said to be hurtful to the human system.

We all know, from what we experience with and within ourselves, that our conscious acts spring from our desires and our fears. Intuition tells us that that is true also of our fellows and of the higher animals. We all try to escape pain and death, while we seek what is pleasant. We are all ruled in what we do by impulses; and these impulses are so organized that our actions in general serve for our self preservation and that of the race. Hunger, love, pain, fear are some of those inner forces which rule the individual’s instinct for self preservation. At the same time, as social beings, we are moved in the relations with our fellow beings by such feelings as sympathy, pride, hate, need for power, pity, and so on. All these primary impulses, not easily described in words, are the springs of man’s actions. All such action would cease if those powerful elemental forces were to cease stirring within us. Though our conduct seems so very different from that of the higher animals, the primary instincts are much alike in them and in us. The most evident difference springs from the important part which is played in man by a relatively strong power of imagination and by the capacity to think, aided as it is by language and other symbolical devices. Thought is the organizing factor in man, intersected between the causal primary instincts and the resulting actions. In that way imagination and intelligence enter into our existence in the part of servants of the primary instincts. But their intervention makes our acts to serve ever less merely the immediate claims of our instincts.

We believe that ‘buckytubes’ are best thought of as a new miracle polymer, However, in this case, the polymer conducts electricity, and that’s a new play.

We do not know of any enzymes or other chemical defined organic substances having specifically acting auto-catalytic properties such as to enable them to construct replicas of themselves. Neither was there a general principle known that would result in pattern-copying; if there were, the basis of life would be easier to come by. Moreover, there was no evidence to show that the enzymes were not products of hereditary determiners or genes, rather than these genes themselves, and they might even be products removed by several or many steps from the genes, just as many other known substances in the cell must be. However, the determiners or genes themselves must conduct, or at least guide, their own replication, so as to lead to the formation of genes just like themselves, in such wise that even their own mutations become .incorporated in the replicas. And this would probably take place by some kind of copying of pattern similar to that postulated by Troland for the enzymes, but requiring some distinctive chemical structure to make it possible. By virtue of this ability of theirs to replicate, these genes–or, if you prefer, genetic material–contained in the nuclear chromosomes and in whatever other portion of the cell manifests this property, such as the chloroplastids of plants, must form the basis of all the complexities of living matter that have arisen subsequent to their own appearance on the scene, in the whole course of biological evolution. That is, this genetic material must underlie all evolution based on mutation and selective multiplication.

We have one great guiding principle which, like the pillar of cloud by day, and the pillar of fire by night, will conduct us, as Moses and the Israelites were once conducted, to an eminence from which we can survey the promised scientific future. That principle is the conservation of energy.

We more readily confess to errors, mistakes, and shortcomings in our conduct than in our thought.

We must painfully acknowledge that, precisely because of its great intellectual developments, the best of man's domesticated animals—the dog—most often becomes the victim of physiological experiments. Only dire necessity can lead one to experiment on cats—on such impatient, loud, malicious animals. During chronic experiments, when the animal, having recovered from its operation, is under lengthy observation, the dog is irreplaceable; moreover, it is extremely touching. It is almost a participant in the experiments conducted upon it, greatly facilitating the success of the research by its understanding and compliance.

When a man of science speaks of his “data,” he knows very well in practice what he means. Certain experiments have been conducted, and have yielded certain observed results, which have been recorded. But when we try to define a “datum” theoretically, the task is not altogether easy. A datum, obviously, must be a fact known by perception. But it is very difficult to arrive at a fact in which there is no element of inference, and yet it would seem improper to call something a “datum” if it involved inferences as well as observation. This constitutes a problem. …

Whenever … a controversy arises in mathematics, the issue is not whether a thing is true or not, but whether the proof might not be conducted more simply in some other way, or whether the proposition demonstrated is sufficiently important for the advancement of the science as to deserve especial enunciation and emphasis, or finally, whether the proposition is not a special case of some other and more general truth which is as easily discovered.

While working with staphylococcus variants a number of culture-plates were set aside on the laboratory bench and examined from time to time. In the examinations these plates were necessarily exposed to the air and they became contaminated with various micro-organisms. It was noticed that around a large colony of a contaminating mould the staphylococcus colonies became transparent and were obviously undergoing lysis. Subcultures of this mould were made and experiments conducted with a view to ascertaining something of the properties of the bacteriolytic substance which had evidently been formed in the mould culture and which had diffused into the surrounding medium. It was found that broth in which the mould had been grown at room temperature for one or two weeks had acquired marked inhibitory, bacteriocidal and bacteriolytic properties to many of the more common pathogenic bacteria.

Why does man regret, even though he may endeavour to banish any such regret, that he has followed the one natural impulse, rather than the other; and why does he further feel that he ought to regret his conduct? Man in this respect differs profoundly from the lower animals.