… (T)he same cause, such as electricity, can simultaneously affect all sensory organs, since they are all sensitive to it; and yet, every sensory nerve reacts to it differently; one nerve perceives it as light, another hears its sound, another one smells it; another tastes the electricity, and another one feels it as pain and shock. One nerve perceives a luminous picture through mechanical irritation, another one hears it as buzzing, another one senses it as pain… He who feels compelled to consider the consequences of these facts cannot but realize that the specific sensibility of nerves for certain impressions is not enough, since all nerves are sensitive to the same cause but react to the same cause in different ways… (S)ensation is not the conduction of a quality or state of external bodies to consciousness, but the conduction of a quality or state of our nerves to consciousness, excited by an external cause.
Law of Specific Nerve Energies.

… the United States was not built by those who waited and rested and wished to look behind them. This country was conquered by those who moved forward, and so will space.

...it would be a simple way of solving the goiter problem. And in addition to that it would be the biggest thing in a medical proposition to be carried out in the state of Michigan, and Michigan is a large place. And as I thought of the thing the more convinced I became that this oughtn't to be a personal thing, This ought to be something done by the Michigan State Medical Society as a body.
Recommending the addition of a trace of iodine to table salt.

“Every moment dies a man,/ Every moment one is born”:
I need hardly point out to you that this calculation would tend to keep the sum total of the world's population in a state of perpetual equipoise whereas it is a well-known fact that the said sum total is constantly on the increase. I would therefore take the liberty of suggesting that in the next edition of your excellent poem the erroneous calculation to which I refer should be corrected as follows:
'Every moment dies a man / And one and a sixteenth is born.” I may add that the exact figures are 1.167, but something must, of course, be conceded to the laws of metre.

“Facts, facts, facts,” cries the scientist if he wants to emphasize the necessity of a firm foundation for science. What is a fact? A fact is a thought that is true. But the scientist will surely not recognize something which depends on men's varying states of mind to be the firm foundation of science.

“Unless,” said I [Socrates], “either philosophers become kings in our states or those whom we now call our kings and rulers take to the pursuit of' philosophy seriously and adequately, and there is a conjunction of these two things, political power and philosophic intelligence, while the motley horde of the natures who at present pursue either apart from the other are compulsorily excluded, there can be no cessation of troubles, dear Glaucon, for our states, nor, I fancy for the human race either. Nor, until this happens, will this constitution which we have been expounding in theory ever be put into practice within the limits of possibility and see the light of the sun.”

[Euclid's Elements] has been for nearly twenty-two centuries the encouragement and guide of that scientific thought which is one thing with the progress of man from a worse to a better state. The encouragement; for it contained a body of knowledge that was really known and could be relied on, and that moreover was growing in extent and application. For even at the time this book was written—shortly after the foundation of the Alexandrian Museum—Mathematics was no longer the merely ideal science of the Platonic school, but had started on her career of conquest over the whole world of Phenomena. The guide; for the aim of every scientific student of every subject was to bring his knowledge of that subject into a form as perfect as that which geometry had attained. Far up on the great mountain of Truth, which all the sciences hope to scale, the foremost of that sacred sisterhood was seen, beckoning for the rest to follow her. And hence she was called, in the dialect of the Pythagoreans, ‘the purifier of the reasonable soul.’

[John Scott Haldane] preferred to work on himself or other human beings who were sufficiently interested in the work to ignore pain or fear … [His] object was not to achieve this state of [pain or fear] but to achieve knowledge which could save other men's lives. His attitute was much more like a good soldier who will risk his life and endure wounds in order to gain victory than that of an ascetic who deliberately undergoes pain. The soldier does not get himself wounded deliberately, and my father did not seek pain in his work though he greeted pain which would have made some people writhe or groan, with laughter.

[Locating, from scratch, the gene related to a disease is like] trying to find a burned-out light bulb in a house located somewhere between the East and West coasts without knowing the state, much less the town or street the house is on.

[Louis Rendu, Bishop of Annecy] collects observations, makes experiments, and tries to obtain numerical results; always taking care, however, so to state his premises and qualify his conclusions that nobody shall be led to ascribe to his numbers a greater accuracy than they merit. It is impossible to read his work, and not feel that he was a man of essentially truthful mind and that science missed an ornament when he was appropriated by the Church.

[On Oxygen, Chlorine, Iodine, Fluorine:] The most important division of ponderable substances seems to be that which represents their electrical energies or their respective inherent states. When the poles of a voltaic apparatus are introduced into a mixture of the simple substances, it is found that four of them go to the positive, while the rest evince their state by passing to the negative pole. As this division coincides with one resulting from a consideration of their most important properties, it is that which I shall adopt as the first.

[Receiving a university scholarship] was fundamentally important to me, to be able to afford going to school, and I still believe so strongly in the value of public education and state-funded universities.

[Relativist] Rel. There is a well-known proposition of Euclid which states that “Any two sides of a triangle are together greater than the third side.” Can either of you tell me whether nowadays there is good reason to believe that this proposition is true?
[Pure Mathematician] Math. For my part, I am quite unable to say whether the proposition is true or not. I can deduce it by trustworthy reasoning from certain other propositions or axioms, which are supposed to be still more elementary. If these axioms are true, the proposition is true; if the axioms are not true, the proposition is not true universally. Whether the axioms are true or not I cannot say, and it is outside my province to consider.

[Some] philosophers have been of opinion that our immortal part acquires during this life certain habits of action or of sentiment, which become forever indissoluble, continuing after death in a future state of existence ... I would apply this ingenious idea to the generation, or production of the embryon, or new animal, which partakes so much of the form and propensities of the parent.

[When combustion occurs,] one body, at least, is oxygenated, and another restored, at the same time, to its combustible state... This view of combustion may serve to show how nature is always the same, and maintains her equilibrium by preserving the same quantities of air and water on the surface of our globe: for as fast as these are consumed in the various processes of combustion, equal quantities are formed, and rise regenerated like the Phoenix from her ashes.
Fulhame believed 'that water was the only source of oxygen, which oxygenates combustible bodies' and that 'the hydrogen of water is the only substance that restores bodies to their combustible state.'

[On the use of scopolamine in criminology], If it is permissible for a state to take life, liberty and property because of crime, it can be made legal to obtain information from a suspected criminal by the use of a drug. If the use of bloodhounds is legal, the use of scopolamine can be made legal.

Between the frontiers of the three super-states Eurasia, Oceania, and Eastasia, and not permanently in possession of any of them, there lies a rough quadrilateral with its corners at Tangier, Brazzaville, Darwin, and Hongkong. These territories contain a bottomless reserve of cheap labour. Whichever power controls equatorial Africa, or the Middle East or Southern India or the Indonesian Archipelago, disposes also of the bodies of hundreds of millions of ill-paid and hardworking coolies, expended by their conquerors like so much coal or oil in the race to turn out more armaments, to capture more territory, to control more labour, to turn out more armaments, to capture more territory, to control…
Thus George Orwell—in his only reference to the less-developed world.
I wish I could disagree with him. Orwell may have erred in not anticipating the withering of direct colonial controls within the “quadrilateral” he speaks about; he may not quite have gauged the vehemence of urges to political self-assertion. Nor, dare I hope, was he right in the sombre picture of conscious and heartless exploitation he has painted. But he did not err in predicting persisting poverty and hunger and overcrowding in 1984 among the less privileged nations.
I would like to live to regret my words but twenty years from now, I am positive, the less-developed world will be as hungry, as relatively undeveloped, and as desperately poor, as today.

Clarke's First Law: When a distinguished but elderly scientist states that something is possible, he is almost certainly right. When he states that something is impossible, he is very probably wrong.

He who doth with the greatest exactness imaginable, weigh every individual thing that shall or hath hapned to his Patient, and may be known from the Observations of his own, or of others, and who afterwards compareth all these with one another, and puts them in an opposite view to such Things as happen in a healthy State; and lastly, from all this with the nicest and severest bridle upon his reasoning faculty riseth to the knowledge of the very first Cause of the Disease, and of the Remedies fit to remove them; He, and only He deserveth the Name of a true Physician.

Mathematical truth has validity independent of place, personality, or human authority. Mathematical relations are not established, nor can they be abrogated, by edict. The multiplication table is international and permanent, not a matter of convention nor of relying upon authority of state or church. The value of π is not amenable to human caprice. The finding of a mathematical theorem may have been a highly romantic episode in the personal life of the discoverer, but it cannot be expected of itself to reveal the race, sex, or temperament of this discoverer. With modern means of widespread communication even mathematical notation tends to be international despite all nationalistic tendencies in the use of words or of type.

Question: Account for the delicate shades of colour sometimes seen on the inside of an oyster shell. State and explain the appearance presented when a beam of light falls upon a sheet of glass on which very fine equi-distant parallel lines have been scratched very close to one another.
Answer: The delicate shades are due to putrefaction; the colours always show best when the oyster has been a bad one. Hence they are considered a defect and are called chromatic aberration.
The scratches on the glass will arrange themselves in rings round the light, as any one may see at night in a tram car.

Question: Explain how to determine the time of vibration of a given tuning-fork, and state what apparatus you would require for the purpose.
Answer: For this determination I should require an accurate watch beating seconds, and a sensitive ear. I mount the fork on a suitable stand, and then, as the second hand of my watch passes the figure 60 on the dial, I draw the bow neatly across one of its prongs. I wait. I listen intently. The throbbing air particles are receiving the pulsations; the beating prongs are giving up their original force; and slowly yet surely the sound dies away. Still I can hear it, but faintly and with close attention; and now only by pressing the bones of my head against its prongs. Finally the last trace disappears. I look at the time and leave the room, having determined the time of vibration of the common “pitch” fork. This process deteriorates the fork considerably, hence a different operation must be performed on a fork which is only lent.

Question: State the relations existing between the pressure, temperature, and density of a given gas. How is it proved that when a gas expands its temperature is diminished?
Answer: Now the answer to the first part of this question is, that the square root of the pressure increases, the square root of the density decreases, and the absolute temperature remains about the same; but as to the last part of the question about a gas expanding when its temperature is diminished, I expect I am intended to say I don't believe a word of it, for a bladder in front of a fire expands, but its temperature is not at all diminished.

Question: State what are the conditions favourable for the formation of dew. Describe an instrument for determining the dew point, and the method of using it.
Answer: This is easily proved from question 1. A body of gas as it ascends expands, cools, and deposits moisture; so if you walk up a hill the body of gas inside you expands, gives its heat to you, and deposits its moisture in the form of dew or common sweat. Hence these are the favourable conditions; and moreover it explains why you get warm by ascending a hill, in opposition to the well-known law of the Conservation of Energy.

That the general characters of the big group to which the embryo belongs appear in development earlier than the special characters. In agreement with this is the fact that the vesicular form is the most general form of all; for what is common in a greater degree to all animals than the opposition of an internal and an external surface?
The less general structural relations are formed after the more general, and so on until the most special appear.
The embryo of any given form, instead of passing through the state of other definite forms, on the contrary separates itself from them.
Fundamentally the embryo of a higher animal form never resembles the adult of another animal form, but only its embryo.

1839—The fermentation satire
THE MYSTERY OF ALCOHOLIC FERMENTATION RESOLVED
(Preliminary Report by Letter) Schwindler
I am about to develop a new theory of wine fermentation … Depending on the weight, these seeds carry fermentation to completion somewhat less than as in the beginning, which is understandable … I shall develop a new theory of wine fermentation [showing] what simple means Nature employs in creating the most amazing phenomena. I owe it to the use of an excellent microscope designed by Pistorius.
When brewer’s yeast is mixed with water the microscope reveals that the yeast dissolves into endless small balls, which are scarcely 1/800th of a line in diameter … If these small balls are placed in sugar water, it can be seen that they consist of the eggs of animals. As they expand, they burst, and from them develop small creatures that multiply with unbelievable rapidity in a most unheard of way. The form of these animals differs from all of the 600 types described up until now. They possess the shape of a Beinsdorff still (without the cooling apparatus). The head of the tube is a sort of proboscis, the inside of which is filled with fine bristles 1/2000th of a line long. Teeth and eyes are not discernible; however, a stomach, intestinal canal, anus (a rose red dot), and organs for secretion of urine are plainly discernible. From the moment they are released from the egg one can see these animals swallow the sugar from the solution and pass it to the stomach. It is digested immediately, a process recognized easily by the resultant evacuation of excrements. In a word, these infusors eat sugar, evacuate ethyl alcohol from the intestinal canal, and carbon dioxide from the urinary organs. The bladder, in the filled state, has the form of a champagne bottle; when empty, it is a small button … As soon as the animals find no more sugar present, they eat each other up, which occurs through a peculiar manipulation; everything is digested down to the eggs which pass unchanged through the intestinal canal. Finally, one again fermentable yeast, namely the seed of the animals, which remain over.

A ... hypothesis may be suggested, which supposes the word 'beginning' as applied by Moses in the first of the Book of Genesis, to express an undefined period of time which was antecedent to the last great change that affected the surface of the earth, and to the creation of its present animal and vegetable inhabitants; during which period a long series of operations and revolutions may have been going on, which, as they are wholly unconnected with the history of the human race, are passed over in silence by the sacred historian, whose only concern with them was largely to state, that the matter of the universe is not eternal and self-existent but was originally created by the power of the Almighty.

A distinguished writer [Siméon Denis Poisson] has thus stated the fundamental definitions of the science:
“The probability of an event is the reason we have to believe that it has taken place, or that it will take place.”
“The measure of the probability of an event is the ratio of the number of cases favourable to that event, to the total number of cases favourable or contrary, and all equally possible” (equally like to happen).
From these definitions it follows that the word probability, in its mathematical acceptation, has reference to the state of our knowledge of the circumstances under which an event may happen or fail. With the degree of information which we possess concerning the circumstances of an event, the reason we have to think that it will occur, or, to use a single term, our expectation of it, will vary. Probability is expectation founded upon partial knowledge. A perfect acquaintance with all the circumstances affecting the occurrence of an event would change expectation into certainty, and leave neither room nor demand for a theory of probabilities.

A great department of thought must have its own inner life, however transcendent may be the importance of its relations to the outside. No department of science, least of all one requiring so high a degree of mental concentration as Mathematics, can be developed entirely, or even mainly, with a view to applications outside its own range. The increased complexity and specialisation of all branches of knowledge makes it true in the present, however it may have been in former times, that important advances in such a department as Mathematics can be expected only from men who are interested in the subject for its own sake, and who, whilst keeping an open mind for suggestions from outside, allow their thought to range freely in those lines of advance which are indicated by the present state of their subject, untrammelled by any preoccupation as to applications to other departments of science. Even with a view to applications, if Mathematics is to be adequately equipped for the purpose of coping with the intricate problems which will be presented to it in the future by Physics, Chemistry and other branches of physical science, many of these problems probably of a character which we cannot at present forecast, it is essential that Mathematics should be allowed to develop freely on its own lines.

A great man, [who] was convinced that the truths of political and moral science are capable of the same certainty as those that form the system of physical science, even in those branches like astronomy that seem to approximate mathematical certainty.
He cherished this belief, for it led to the consoling hope that humanity would inevitably make progress toward a state of happiness and improved character even as it has already done in its knowledge of the truth.

A hundred years ago, the electric telegraph made possible—indeed, inevitable—the United States of America. The communications satellite will make equally inevitable a United Nations of Earth; let us hope that the transition period will not be equally bloody.

A man in twenty-four hours converts as much as seven ounces of carbon into carbonic acid; a milch cow will convert seventy ounces, and a horse seventy-nine ounces, solely by the act of respiration. That is, the horse in twenty-four hours burns seventy-nine ounces of charcoal, or carbon, in his organs of respiration to supply his natural warmth in that time ..., not in a free state, but in a state of combination.

A physician’s subject of study is necessarily the patient, and his first field for observation is the hospital. But if clinical observation teaches him to know the form and course of diseases, it cannot suffice to make him understand their nature; to this end he must penetrate into the body to find which of the internal parts are injured in their functions. That is why dissection of cadavers and microscopic study of diseases were soon added to clinical observation. But to-day these various methods no longer suffice; we must push investigation further and, in analyzing the elementary phenomena of organic bodies, must compare normal with abnormal states. We showed elsewhere how incapable is anatomy alone to take account of vital phenenoma, and we saw that we must add study of all physico-chemical conditions which contribute necessary elements to normal or pathological manifestations of life. This simple suggestion already makes us feel that the laboratory of a physiologist-physician must be the most complicated of all laboratories, because he has to experiment with phenomena of life which are the most complex of all natural phenomena.

A road across the United States; Let’s build it before we’re too old to enjoy it. [About the Lincoln Highway]

A State without the means of some change is without the means of its conservation.

A world that did not lift a finger when Hitler was wiping out six million Jewish men, women, and children is now saying that the Jewish state of Israel will not survive if it does not come to terms with the Arabs. My feeling is that no one in this universe has the right and the competence to tell Israel what it has to do in order to survive. On the contrary, it is Israel that can tell us what to do. It can tell us that we shall not survive if we do not cultivate and celebrate courage, if we coddle traitors and deserters, bargain with terrorists, court enemies, and scorn friends.

Above all things, good policy is to be used that the treasure and moneys in a state be not gathered into few hands. For otherwise a state may have a great stock, and yet starve. And money is like muck, not good except it be spread.

According to this view of the matter, there is nothing casual in the formation of Metamorphic Rocks. All strata, once buried deep enough, (and due TIME allowed!!!) must assume that state,—none can escape. All records of former worlds must ultimately perish.

Accordingly the primordial state of things which I picture is an even distribution of protons and electrons, extremely diffuse and filling all (spherical) space, remaining nearly balanced for an exceedingly long time until its inherent instability prevails. We shall see later that the density of this distribution can be calculated; it was about one proton and electron per litre. There is no hurry for anything to begin to happen. But at last small irregular tendencies accumulate, and evolution gets under way. The first stage is the formation of condensations ultimately to become the galaxies; this, as we have seen, started off an expansion, which then automatically increased in speed until it is now manifested to us in the recession of the spiral nebulae.
As the matter drew closer together in the condensations, the various evolutionary processes followed—evolution of stars, evolution of the more complex elements, evolution of planets and life.

Adam, the first man, didn’t know anything about the nucleus but Dr. George Gamow, visiting professor from George Washington University, pretends he does. He says for example that the nucleus is 0.00000000000003 feet in diameter. Nobody believes it, but that doesn't make any difference to him.
He also says that the nuclear energy contained in a pound of lithium is enough to run the United States Navy for a period of three years. But to get this energy you would have to heat a mixture of lithium and hydrogen up to 50,000,000 degrees Fahrenheit. If one has a little stove of this temperature installed at Stanford, it would burn everything alive within a radius of 10,000 miles and broil all the fish in the Pacific Ocean.
If you could go as fast as nuclear particles generally do, it wouldn’t take you more than one ten-thousandth of a second to go to Miller's where you could meet Gamow and get more details.

After a short period spent in Brussels as a guest of a neurological institute, I returned to Turin on the verge of the invasion of Belgium by the German army, Spring 1940, to join my family. The two alternatives left then to us were either to emigrate to the United States, or to pursue some activity that needed neither support nor connection with the outside Aryan world where we lived. My family chose this second alternative. I then decided to build a small research unit at home and installed it in my bedroom.

After all, most men are incapable of deciding for themselves, and have got to have a leader somewhere. If the new discoveries in mass suggestion enable us to make government easier, not only political, but moral and aesthetic, why not welcome them like other useful inventions? Why should science be limited to improvements in our control over nature, and exclude the most important part of our environment, our fellows? Get on the inside, join, as I used to be told, some party, and learn where the ropes come down within your reach. Adopt the high calling of Manipulator and save the State.
Such Machiavellis are not confined to Russia and Italy; one may find them all about even in this Land of the Free. … Still there remains in me a strange misgiving about making use of one’s fellows through an appeal to their weaknesses, even when all you do is to select their objects for them. In the elegant diction of Mr. Mencken, and in spite of the great weight of his authority, a government of the boobs, for the boobs and by the boobs to me still has its morbid charms.

Alcoholism, the opium habit and tobaccoism are a trio of poison habits which have been weighty handicaps to human progress during the last three centuries. In the United States, the subtle spell of opium has been broken by restrictive legislation; the grip of the rum demon has been loosened by the Prohibition Amendment to the Constitution, but the tobacco habit still maintains its strangle-hold and more than one hundred million victims of tobaccoism daily burn incense to the smoke god.

All fresh meat is eaten in a state of decay. The process may not have proceeded so far that the dull human nose can discover it, but a carrion bird or a carrion fly can smell it from afar.

All of our experience indicates that life can manifest itself only in a concrete form, and that it is bound to certain substantial loci. These loci are cells and cell formations. But we are far from seeking the last and highest level of understanding in the morphology of these loci of life. Anatomy does not exclude physiology, but physiology certainly presupposes anatomy. The phenomena that the physiologist investigates occur in special organs with quite characteristic anatomical arrangements; the various morphological parts disclosed by the anatomist are the bearers of properties or, if you will, of forces probed by the physiologist; when the physiologist has established a law, whether through physical or chemical investigation, the anatomist can still proudly state: This is the structure in which the law becomes manifest.

All palaetiological sciences, all speculations which attempt to ascend from the present to the remote past, by the chain of causation, do also, by an inevitable consequence, urge us to look for the beginning of the state of things which we thus contemplate; but in none of these cases have men been able, by the aid of science, to arrive at a beginning which is homogeneous with the known course of events. The first origin of language, of civilization, of law and government, cannot be clearly made out by reasoning and research; and just as little, we may expect, will a knowledge of the origin of the existing and extinct species of plants and animals, be the result of physiological and geological investigation.

All things are made of atoms—little particles that move around in perpetual motion, attracting each other when they are a little distance apart, but repelling upon being squeezed into one another. In that one sentence ... there is an enormous amount of information about the world.
His suggestion that the most valuable information on scientific knowledge in a single sentence using the fewest words is to state the atomic hypothesis.

Although a science fair can seem like a big “pain” it can help you understand important scientific principles, such as Newton’s First Law of Inertia, which states: “A body at rest will remain at rest until 8:45 p.m. the night before the science fair project is due, at which point the body will come rushing to the body’s parents, who are already in their pajamas, and shout, “I JUST REMEMBERED THE SCIENCE FAIR IS TOMORROW AND WE GOTTA GO TO THE STORE RIGHT NOW!”

An evolution is a series of events that in itself as series is purely physical, — a set of necessary occurrences in the world of space and time. An egg develops into a chick; … a planet condenses from the fluid state, and develops the life that for millions of years makes it so wondrous a place. Look upon all these things descriptively, and you shall see nothing but matter moving instant after instant, each instant containing in its full description the necessity of passing over into the next. … But look at the whole appreciatively, historically, synthetically, as a musician listens to a symphony, as a spectator watches a drama. Now you shall seem to have seen, in phenomenal form, a story.

An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going. But this should not be taken to imply that there are good reasons to believe that it could not have started on the earth by a perfectly reasonable sequence of fairly ordinary chemical reactions. The plain fact is that the time available was too long, the many microenvironments on the earth’s surface too diverse, the various chemical possibilities too numerous and our own knowledge and imagination too feeble to allow us to be able to unravel exactly how it might or might not have happened such a long time ago, especially as we have no experimental evidence from that era to check our ideas against.

And by the influence of heat, light, and electrical powers, there is a constant series of changes [in animal and vegetal substances]; matter assumes new forms, the destruction of one order of beings tends to the conservation of another, solution and consolidation, decay and renovation, are connected, and whilst the parts of the system, continue in a state of fluctuation and change, the order and harmony of the whole remain unalterable.

And men ought to know that from nothing else but thence [from the brain] come joys, delights, laughter and sports, and sorrows, griefs, despondency, and lamentations. And by this, in an especial manner, we acquire wisdom and knowledge, and see and hear, and know what are foul and hat are fair, what are bad and what are good, what are sweet, and what unsavory... And by the same organ we become mad and delirious, and fears and terrors assail us... All these things we endure from the brain, when it is not healthy... In these ways I am of the opinion that the brain exercises the greatest power in the man. This is the interpreter to us of those things which emanate from the air, when it [the brain] happens to be in a sound state.

And who can doubt that it will lead to the worst disorders when minds created free by God are compelled to submit slavishly to an outside will? When we are told to deny our senses and subject them to the whim of others? When people devoid of whatsoever competence are made judges over experts and are granted authority to treat them as they please? These are the novelties which are apt to bring about the ruin of commonwealths and the subversion of the state.

Anyone who considers arithmetical methods of producing random digits is, of course, in the state of sin. For, as has been pointed out several times, there is no such thing as a random number—there are only methods to produce random numbers, and a strict arithmetic procedure of course is not such a method.

Archimedes … had stated that given the force, any given weight might be moved, and even boasted, we are told, relying on the strength of demonstration, that if there were another earth, by going into it he could remove this. Hiero being struck with amazement at this, and entreating him to make good this problem by actual experiment, and show some great weight moved by a small engine, he fixed accordingly upon a ship of burden out of the king’s arsenal, which could not be drawn out of the dock without great labor and many men; and, loading her with many passengers and a full freight, sitting himself the while far off with no great endeavor, but only holding the head of the pulley in his hand and drawing the cords by degrees, he drew the ship in a straight line, as smoothly and evenly, as if she had been in the sea. The king, astonished at this, and convinced of the power of the art, prevailed upon Archimedes to make him engines accommodated to all the purposes, offensive and defensive, of a siege. … the apparatus was, in most opportune time, ready at hand for the Syracusans, and with it also the engineer himself.

Art and Religion are, then, two roads by which men escape from circumstance to ecstasy. Between aesthetic and religious rapture there is a family alliance. Art and Religion are means to similar states of mind.

Art arises in those strange complexities of action that are called human beings. It is a kind of human behavior. As such it is not magic, except as human beings are magical. Nor is it concerned in absolutes, eternities, “forms,” beyond those that may reside in the context of the human being and be subject to his vicissitudes. Art is not an inner state of consciousness, whatever that may mean. Neither is it essentially a supreme form of communication. Art is human behavior, and its values are contained in human behavior.

As a result of the phenomenally rapid change and growth of physics, the men and women who did their great work one or two generations ago may be our distant predecessors in terms of the state of the field, but they are our close neighbors in terms of time and tastes. This may be an unprecedented state of affairs among professionals; one can perhaps be forgiven if one characterizes it epigrammatically with a disastrously mixed metaphor; in the sciences, we are now uniquely privileged to sit side-by-side with the giants on whose shoulders we stand.

As geologists, we learn that it is not only the present condition of the globe that has been suited to the accommodation of myriads of living creatures, but that many former states also have been equally adapted to the organization and habits of prior races of beings. The disposition of the seas, continents, and islands, and the climates have varied; so it appears that the species have been changed, and yet they have all been so modelled, on types analogous to those of existing plants and animals, as to indicate throughout a perfect harmony of design and unity of purpose. To assume that the evidence of the beginning or end of so vast a scheme lies within the reach of our philosophical inquiries, or even of our speculations, appears to us inconsistent with a just estimate of the relations which subsist between the finite powers of man and the attributes of an Infinite and Eternal Being.

As our researches have made clear, an animal high in the organic scale only reaches this rank by passing through all the intermediate states which separate it from the animals placed below it. Man only becomes man after traversing transitional organisatory states which assimilate him first to fish, then to reptiles, then to birds and mammals.

Astrology is framed by the devil, to the end people may be scared from entering into the state of matrimony, and from every divine and human office and calling.

At fertilization, these two “haploid” nuclei are added together to make a “diploid” nucleus that now contains 2a, 2b and so on; and, by the splitting of each chromosome and the regulated karyokinetic separation of the daughter chromosomes, this double series is inherited by both of the primary blastomeres. In the resulting resting nuclei the individual chromosomes are apparently destroyed. But we have the strongest of indications that, in the stroma of the resting nucleus, every one of the chromosomes that enters the nucleus survives as a well-defined region; and as the cell prepares for its next division this region again gives rise to the same chromosome (Theory of the Individuality of the Chromosomes). In this way the two sets of chromosomes brought together at fertilization are inherited by all the cells of the new individual. It is only in the germinal cells that the so called reduction division converts the double series into a single one. Out of the diploid state, the haploid is once again generated.

At present we begin to feel impatient, and to wish for a new state of chemical elements. For a time the desire was to add to the metals, now we wish to diminish their number. They increase upon us continually, and threaten to enclose within their ranks the bounds of our fair fields of chemical science. The rocks of the mountain and the soil of the plain, the sands of the sea and the salts that are in it, have given way to the powers we have been able to apply to them, but only to be replaced by metals.

Available energy is energy which we can direct into any desired channel. Dissipated energy is energy which we cannot lay hold of and direct at pleasure, such as the energy of the confused agitation of molecules which we call heat. Now, confusion, like the correlative term order, is not a property of material things in themselves, but only in relation to the mind which perceives them. A memorandum-book does not, provided it is neatly written, appear confused to an illiterate person, or to the owner who understands it thoroughly, but to any other person able to read it appears to be inextricably confused. Similarly the notion of dissipated energy could not occur to a being who could not turn any of the energies of nature to his own account, or to one who could trace the motion of every molecule and seize it at the right moment. It is only to a being in the intermediate stage, who can lay hold of some forms of energy while others elude his grasp, that energy appears to be passing inevitably from the available to the dissipated state.

Ax: 100 Every thing doth naturally persevere in yt state in wch it is unlesse it bee interrupted by some externall cause, hence… [a] body once moved will always keepe ye same celerity, quantity & determination of its motion.

Being perpetually charmed by his familiar siren, that is, by his geometry, he [Archimedes] neglected to eat and drink and took no care of his person; that he was often carried by force to the baths, and when there he would trace geometrical figures in the ashes of the fire, and with his finger draws lines upon his body when it was anointed with oil, being in a state of great ecstasy and divinely possessed by his science.

Biological diversity is the key to the maintenance of the world as we know it. Life in a local site struck down by a passing storm springs back quickly: opportunistic species rush in to fill the spaces. They entrain the succession that circles back to something resembling the original state of the environment.

But as my conclusions have lately been much misrepresented, and it has been stated that I attribute the modification of species exclusively to natural selection, I may be permitted to remark that in the first edition of this work, and subsequently, I placed in a most conspicuous position—namely, at the close of the Introduction—the following words: “I am convinced that natural selection has been the main but not the exclusive means of modification.” This has been of no avail. Great is the power of steady misrepresentation; but the history of science shows that fortunately this power does not long endure.

But how to raise a sum in the different States has been my greatest difficulty.

But we must here state that we should not see anything if there were a vacuum. But this would not be due to some nature hindering species, and resisting it, but because of the lack of a nature suitable for the multiplication of species; for species is a natural thing, and therefore needs a natural medium; but in a vacuum nature does not exist.

By research in pure science I mean research made without any idea of application to industrial matters but solely with the view of extending our knowledge of the Laws of Nature. I will give just one example of the ‘utility’ of this kind of research, one that has been brought into great prominence by the War—I mean the use of X-rays in surgery. Now, not to speak of what is beyond money value, the saving of pain, or, it may be, the life of the wounded, and of bitter grief to those who loved them, the benefit which the state has derived from the restoration of so many to life and limb, able to render services which would otherwise have been lost, is almost incalculable. Now, how was this method discovered? It was not the result of a research in applied science starting to find an improved method of locating bullet wounds. This might have led to improved probes, but we cannot imagine it leading to the discovery of X-rays. No, this method is due to an investigation in pure science, made with the object of discovering what is the nature of Electricity. The experiments which led to this discovery seemed to be as remote from ‘humanistic interest’ —to use a much misappropriated word—as anything that could well be imagined. The apparatus consisted of glass vessels from which the last drops of air had been sucked, and which emitted a weird greenish light when stimulated by formidable looking instruments called induction coils. Near by, perhaps, were great coils of wire and iron built up into electro-magnets. I know well the impression it made on the average spectator, for I have been occupied in experiments of this kind nearly all my life, notwithstanding the advice, given in perfect good faith, by non-scientific visitors to the laboratory, to put that aside and spend my time on something useful.

By teaching us how to cultivate each ferment in its purity—in other words, by teaching us how to rear the individual organism apart from all others,—Pasteur has enabled us to avoid all these errors. And where this isolation of a particular organism has been duly effected it grows and multiplies indefinitely, but no change of it into another organism is ever observed. In Pasteur’s researches the Bacterium remained a Bacterium, the Vibrio a Vibrio, the Penicillium a Penicillium, and the Torula a Torula. Sow any of these in a state of purity in an appropriate liquid; you get it, and it alone, in the subsequent crop. In like manner, sow smallpox in the human body, your crop is smallpox. Sow there scarlatina, and your crop is scarlatina. Sow typhoid virus, your crop is typhoid—cholera, your crop is cholera. The disease bears as constant a relation to its contagium as the microscopic organisms just enumerated do to their germs, or indeed as a thistle does to its seed.

By what process of reasoning should the State of Texas be more concerned in the conviction of the guilty than in the acquittal of the innocent? [Urging the use of scopolamine “truth serum” to determine innocence.]

Camels, unlike most animals, regulate their body temperatures at two different but stable states. During daytime in the desert, when it is unbearably hot, camels regulate close to 40°C, a close enough match to the air temperature to avoid having to cool by sweating precious water. At night the desert is cold, and even cold enough for frost; the camel would seriously lose heat if it tried to stay at 40°C, so it moves its regulation to a more suitable 34°C, which is warm.

Can I pay any higher tribute to a man [George Gaylord Simpson] than to state that his work both established a profession and sowed the seeds for its own revision? If Simpson had reached final truth, he either would have been a priest or would have chosen a dull profession. The history of life cannot be a dull profession.

Certainly, speaking for the United States of America, I pledge that, as we sign this treaty in an era of negotiation, we consider it only one step toward a greater goal: the control of nuclear weapons on earth and the reduction of the danger that hangs over all nations as long as those weapons are not controlled.

Children are told that an apple fell on Isaac Newton’s head and he was led to state the law of gravity. This, of course, is pure foolishness. What Newton discovered was that any two particles in the universe attract each other with a force that is proportional to the product of their masses and inversely proportional to the square of the distance between them. This is not learned from a falling apple, but by observing quantities of data and developing a mathematical theory that can be verified by additional data. Data gathered by Galileo on falling bodies and by Johannes Kepler on motions of the planets were invaluable aids to Newton. Unfortunately, such false impressions about science are not universally outgrown like the Santa Claus myth, and some people who don’t study much science go to their graves thinking that the human race took until the mid-seventeenth century to notice that objects fall.

Chromosomes … [contain] some kind of code-script the entire pattern of the individual’s future development and of its functioning in the mature state. Every complete set of chromosomes contains the full code.

City after city, state after state, had essentially failed in their efforts to protect their air and their water, the land, the health of their citizens. By 1970, our city’ skylines were so polluted that in many places it was all but impossible to see from one city skyscraper to another. … We had rivers that were fouled with raw sewage and toxic chemicals. One actually caught on fire. There was a very famous photograph from my teenage years of the Cuyahoga River burning. In fact, it was memorialized in a song at the time.

Climate change threatens every corner of our country, every sector of our economy and the health and future of every child. We are already seeing its impacts and we know the poorest and most vulnerable people in the United States and around the world will suffer most of all.

Concerning alchemy it is more difficult to discover the actual state of things, in that the historians who specialise in this field seem sometimes to be under the wrath of God themselves; for, like those who write of the Bacon-Shakespeare controversy or on Spanish politics, they seem to become tinctured with the kind of lunacy they set out to describe.

Consciousness is an electrical phenomenon which arises from a state of being which we can feel.

Conservation is a state of harmony between men and land.

Coolidge is a better example of evolution than either Bryan or Darrow, for he knows when not to talk, which is the biggest asset the monkey possesses over the human.
[Referring to the Scopes trial, with Darrow defending a teacher being prosecuted for teaching evolution in the state of Tennessee.]

Could the young but realize how soon they will become mere walking bundles of habits, they would give more heed to their conduct while in the plastic state. We are spinning our own fates, good or evil, and never to be undone.

Courtship, properly understood, is the process whereby both the male and the female are brought into that state of sexual tumescence which is a more or less necessary condition for sexual intercourse. The play of courtship cannot, therefore, be considered to be definitely brought to an end by the ceremony of marriage; it may more properly be regarded as the natural preliminary to every act of coitus.

Darwin grasped the philosophical bleakness with his characteristic courage. He argued that hope and morality cannot, and should not, be passively read in the construction of nature. Aesthetic and moral truths, as human concepts, must be shaped in human terms, not ‘discovered’ in nature. We must formulate these answers for ourselves and then approach nature as a partner who can answer other kinds of questions for us–questions about the factual state of the universe, not about the meaning of human life. If we grant nature the independence of her own domain–her answers unframed in human terms–then we can grasp her exquisite beauty in a free and humble way. For then we become liberated to approach nature without the burden of an inappropriate and impossible quest for moral messages to assuage our hopes and fears. We can pay our proper respect to nature’s independence and read her own ways as beauty or inspiration in our different terms.

Despite the vision and the far-seeing wisdom of our wartime heads of state, the physicists felt a peculiarly intimate responsibility for suggesting, for supporting, and in the end, in large measure, for achieving the realization of atomic weapons. Nor can we forget that these weapons, as they were in fact used, dramatized so mercilessly the inhumanity and evil of modern war. In some sort of crude sense which no vulgarity, no humor, no overstatement can quite extinguish, the physicists have known sin; and this is a knowledge which they cannot lose.

Disease is an abnormal state of the body which primarily and independently produces a disturbance in the normal functions of the body. It may be an abnormality of temperament or form (structure). Symptom is a manifestation of some abnormal state in the body. It may be harmful as a colic pain or harmless as the flushing of cheeks in peripneumonia.

Do these models give a pointer to God? The steady-state universe, the Hawking model... and the infinitely oscillating model decidedly do not. One might almost regard them as models manufactured for a Society of Atheists.

During the 1930s, Nazi oppression drove numerous scientists to Great Britain and the United States, and they were a key factor in the development of the nuclear bomb—a development widely touted in the United States as based on “Yankee know-how.” Except that virtually all the Yankees had foreign accents.

Effects vary with the conditions which bring them to pass, but laws do not vary. Physiological and pathological states are ruled by the same forces; they differ only because of the special conditions under which the vital laws manifest themselves.

Ere long intelligence—transmitted without wires—will throb through the earth like a pulse through a living organism. The wonder is that, with the present state of knowledge and the experiences gained, no attempt is being made to disturb the electrostatic or magnetic condition of the earth, and transmit, if nothing else, intelligence.

Every appearance in nature corresponds to some state of the mind, and that state of the mind can only be described by presenting that natural appearance as its picture. An enraged man is a lion, a cunning man is a fox, a firm man is a rock, a learned man is a torch. A lamb is innocence; a snake is subtle spite; flowers express to us the delicate affections. Light and darkness are our familiar expressions for knowledge and ignorance ; and heat for love. Visible distance behind and before us, is respectively our image of memory and hope.

Every body continues in its state of rest or uniform motion in a straight line, except in so far as it doesn’t. … The suggestion that the body really wanted to go straight but some mysterious agent made it go crooked is picturesque but unscientific.

Every body perseveres in its state of being at rest or of moving uniformly straight forward, except insofar as it is compelled to change its state by forces impressed.

Every great scientific truth goes through three states: first, people say it conflicts with the Bible; next, they say it has been discovered before; lastly, they say they always believed it.

Every lecture should state one main point and repeat it over and over, like a theme with variations. An audience is like a herd of cows, moving slowly in the direction they are being driven towards. If we make one point, we have a good chance that the audience will take the right direction; if we make several points, then the cows will scatter all over the field. The audience will lose interest and everyone will go back to the thoughts they interrupted in order to come to our lecture.

Every mathematician worthy of the name has experienced, if only rarely, the state of lucid exaltation in which one thought succeeds another as if miraculously… this feeling may last for hours at a time, even for days. Once you have experienced it, you are eager to repeat it but unable to do it at will, unless perhaps by dogged work….

Every work of science great enough to be well remembered for a few generations affords some exemplification of the defective state of the art of reasoning of the time when it was written; and each chief step in science has been a lesson in logic.

Evolution is a theory of organic change, but it does not imply, as many people assume, that ceaseless flux is the irreducible state of nature and that structure is but a temporary incarnation of the moment. Change is more often a rapid transition between stable states than a continuous transformation at slow and steady rates. We live in a world of structure and legitimate distinction. Species are the units of nature’s morphology.

Evolution is the conviction that organisms developed their current forms by an extended history of continual transformation, and that ties of genealogy bind all living things into one nexus. Panselectionism is a denial of history, for perfection covers the tracks of time. A perfect wing may have evolved to its current state, but it may have been created just as we find it. We simply cannot tell if perfection be our only evidence. As Darwin himself understood so well, the primary proofs of evolution are oddities and imperfections that must record pathways of historical descent–the panda’s thumb and the flamingo’s smile of my book titles (chosen to illustrate this paramount principle of history).

EXTINCTION, n. The raw material out of which theology created the future state.

Few people doubt that the Apollo missions to the Moon as well as the precursory Mercury and Gemini missions not only had a valuable role for the United States in its Cold War with the Soviet Union but also lifted the spirits of humankind. In addition, the returned samples of lunar surface material fueled important scientific discoveries.

Few will deny that even in the first scientific instruction in mathematics the most rigorous method is to be given preference over all others. Especially will every teacher prefer a consistent proof to one which is based on fallacies or proceeds in a vicious circle, indeed it will be morally impossible for the teacher to present a proof of the latter kind consciously and thus in a sense deceive his pupils. Notwithstanding these objectionable so-called proofs, so far as the foundation and the development of the system is concerned, predominate in our textbooks to the present time. Perhaps it will be answered, that rigorous proof is found too difficult for the pupil’s power of comprehension. Should this be anywhere the case,—which would only indicate some defect in the plan or treatment of the whole,—the only remedy would be to merely state the theorem in a historic way, and forego a proof with the frank confession that no proof has been found which could be comprehended by the pupil; a remedy which is ever doubtful and should only be applied in the case of extreme necessity. But this remedy is to be preferred to a proof which is no proof, and is therefore either wholly unintelligible to the pupil, or deceives him with an appearance of knowledge which opens the door to all superficiality and lack of scientific method.

Finally in a large population, divided and subdivided into partially isolated local races of small size, there is a continually shifting differentiation among the latter (intensified by local differences in selection but occurring under uniform and static conditions) which inevitably brings about an indefinitely continuing, irreversible, adaptive, and much more rapid evolution of the species. Complete isolation in this case, and more slowly in the preceding, originates new species differing for the most part in nonadaptive parallel orthogenetic lines, in accordance with the conditions. It is suggested, in conclusion, that the differing statistical situations to be expected among natural species are adequate to account for the different sorts of evolutionary processes which have been described, and that, in particular, conditions in nature are often such as to bring about the state of poise among opposing tendencies on which an indefinitely continuing evolutionary process depends.

Finite systems of deterministic ordinary nonlinear differential equations may be designed to represent forced dissipative hydrodynamic flow. Solutions of these equations can be identified with trajectories in phase space. For those systems with bounded solutions, it is found that nonperiodic solutions are ordinarily unstable with respect to small modifications, so that slightly differing initial states can evolve into considerably different states. Systems with bounded solutions are shown to possess bounded numerical solutions.
A simple system representing cellular convection is solved numerically. All of the solutions are found to be unstable, and almost all of them are nonperiodic.
The feasibility of very-long-range weather prediction is examined in the light of these results

First, the chief character, who is supposed to be a professional astronomer, spends his time fund raising and doing calculations at his desk, rather than observing the sky. Second, the driving force of a scientific project is institutional self-aggrandizement rather than intellectual curiosity.
[About the state of affairs in academia.]

For it is the nature of that which is the same and remains in the same state always to produce the same effects, so either there will always be coming to be or perishing.

For the sake of our children and our future, we must do more to combat climate change. Now, it’s true that no single event makes a trend. But the fact is the 12 hottest years on record have all come in the last 15. Heat waves, droughts, wildfires, floods—all are now more frequent and more intense. We can choose to believe that Superstorm Sandy, and the most severe drought in decades, and the worst wildfires some states have ever seen were all just a freak coincidence. Or we can choose to believe in the overwhelming judgment of science—and act before it’s too late.

For undemocratic reasons and for motives not of State, they arrive at their conclusions—largely inarticulate. Being void of self-expression they confide their views to none; but sometimes in a smoking room, one learns why things were done.

Freudian psychoanalytical theory is a mythology that answers pretty well to Levi-Strauss's descriptions. It brings some kind of order into incoherence; it, too, hangs together, makes sense, leaves no loose ends, and is never (but never) at a loss for explanation. In a state of bewilderment it may therefore bring comfort and relief … give its subject a new and deeper understanding of his own condition and of the nature of his relationship to his fellow men. A mythical structure will be built up around him which makes sense and is believable-in, regardless of whether or not it is true.