[T]he human desire to escape the flesh, which took one form in asceticism, might take another form in the creation of machines. Thus, the wish to rise above the bestial body manifested itself not only in angels but in mechanical creatures. Certainly, once machines existed, humans clearly attached to them feelings of escape from the flesh.

A physician’s subject of study is necessarily the patient, and his first field for observation is the hospital. But if clinical observation teaches him to know the form and course of diseases, it cannot suffice to make him understand their nature; to this end he must penetrate into the body to find which of the internal parts are injured in their functions. That is why dissection of cadavers and microscopic study of diseases were soon added to clinical observation. But to-day these various methods no longer suffice; we must push investigation further and, in analyzing the elementary phenomena of organic bodies, must compare normal with abnormal states. We showed elsewhere how incapable is anatomy alone to take account of vital phenenoma, and we saw that we must add study of all physico-chemical conditions which contribute necessary elements to normal or pathological manifestations of life. This simple suggestion already makes us feel that the laboratory of a physiologist-physician must be the most complicated of all laboratories, because he has to experiment with phenomena of life which are the most complex of all natural phenomena.

A rock or stone is not a subject that, of itself, may interest a philosopher to study; but, when he comes to see the necessity of those hard bodies, in the constitution of this earth, or for the permanency of the land on which we dwell, and when he finds that there are means wisely provided for the renovation of this necessary decaying part, as well as that of every other, he then, with pleasure, contemplates this manifestation of design, and thus connects the mineral system of this earth with that by which the heavenly bodies are made to move perpetually in their orbits.

A social fact is every way of acting, fixed or not, capable of exercising on the individual an external constraint; or again, every way of acting which is general throughout a given society, while at the same time existing in its own right independent of its individual manifestations.

A universe without law would be a universe without order, without the possibility of science, and the manifestations of an intelligent governor and creator.

All living organisms are but leaves on the same tree of life. The various functions of plants and animals and their specialized organs are manifestations of the same living matter. This adapts itself to different jobs and circumstances, but operates on the same basic principles. Muscle contraction is only one of these adaptations. In principle it would not matter whether we studied nerve, kidney or muscle to understand the basic principles of life. In practice, however, it matters a great deal.

All the life of the universe may be regarded as manifestations of energy masquerading in various forms, and all the changes in the universe as energy running about from one of these forms to the other, but always without altering the total amount.

Being the most striking manifestation of the art of metal structures by which our engineers have shown in Europe, it [the Eiffel Tower] is one of the most striking of our modern national genius.

Built up of carbon, hydrogen, oxygen, nitrogen, together with traces of a few other elements, yet of a complexity of structure that has hitherto resisted all attempts at complete analysis, protoplasm is at once the most enduring and the most easily destroyed of substances; its molecules are constantly breaking down to furnish the power for the manifestations of vital phenomena, and yet, through its remarkable property of assimilation, a power possessed by nothing else upon earth, it constantly builds up its substance anew from the surrounding medium.

Chemistry has the same quickening and suggestive influence upon the algebraist as a visit to the Royal Academy, or the old masters may be supposed to have on a Browning or a Tennyson. Indeed it seems to me that an exact homology exists between painting and poetry on the one hand and modern chemistry and modern algebra on the other. In poetry and algebra we have the pure idea elaborated and expressed through the vehicle of language, in painting and chemistry the idea enveloped in matter, depending in part on manual processes and the resources of art for its due manifestation.

Connected by innumerable ties with abstract science, Physiology is yet in the most intimate relation with humanity; and by teaching us that law and order, and a definite scheme of development, regulate even the strangest and wildest manifestations of individual life, she prepares the student to look for a goal even amidst the erratic wanderings of mankind, and to believe that history offers something more than an entertaining chaos—a journal of a toilsome, tragi-comic march nowither.

Disease is an abnormal state of the body which primarily and independently produces a disturbance in the normal functions of the body. It may be an abnormality of temperament or form (structure). Symptom is a manifestation of some abnormal state in the body. It may be harmful as a colic pain or harmless as the flushing of cheeks in peripneumonia.

Disease is not something personal and special, but only a manifestation of life under modified conditions, operating according to the same laws as apply to the living body at all times, from the first moment until death.

Essentially only one thing in life interests us: our psychical constitution, the mechanism of which was and is wrapped in darkness. All human resources, art, religion, literature, philosophy and historical sciences, all of them join in bringing lights in this darkness. But man has still another powerful resource: natural science with its strictly objective methods. This science, as we all know, is making huge progress every day. The facts and considerations which I have placed before you at the end of my lecture are one out of numerous attempts to employ a consistent, purely scientific method of thinking in the study of the mechanism of the highest manifestations of life in the dog, the representative of the animal kingdom that is man's best friend.

Everest for me, and I believe for the world, is the physical and symbolic manifestation of overcoming odds to achieve a dream.

Florey was not an easy personality. His drive and ambition were manifest from the day he arrived ... He could be ruthless and selfish; on the other hand, he could show kindliness, a warm humanity and, at times, sentiment and a sense of humour. He displayed utter integrity and he was scathing of humbug and pretence. His attitude was always—&ldqo;You must take me as you find me” But to cope with him at times, you had to do battle, raise your voice as high as his and never let him shout you down. You had to raise your pitch to his but if you insisted on your right he was always, in the end, very fair. I must say that at times, he went out of his way to cut people down to size with some very destructive criticism. But I must also say in the years I knew him he did not once utter a word of praise about himself.

For me, the study of these laws is inseparable from a love of Nature in all its manifestations. The beauty of the basic laws of natural science, as revealed in the study of particles and of the cosmos, is allied to the litheness of a merganser diving in a pure Swedish lake, or the grace of a dolphin leaving shining trails at night in the Gulf of California.

Free men are aware of the imperfection inherent in human affairs, and they are willing to fight and die for that which is not perfect. They know that basic human problems can have no final solutions, that our freedom, justice, equality, etc. are far from absolute, and that the good life is compounded of half measures, compromises, lesser evils, and gropings toward the perfect. The rejection of approximations and the insistence on absolutes are the manifestation of a nihilism that loathes freedom, tolerance, and equity.

Gentlemen, as we study the universe we see everywhere the most tremendous manifestations of force. In our own experience we know of but one source of force, namely will. How then can we help regarding the forces we see in nature as due to the will of some omnipresent, omnipotent being? Gentlemen, there must be a GOD.

Herewith I offer you the Omnipotent Finger of God in the anatomy of a louse: wherein you will find miracles heaped on miracles and will see the wisdom of God clearly manifested in a minute point.

Histology is an exotic meal, but can be as repulsive as a dose of medicine for students who are obliged to study it, and little loved by doctors who have finished their study of it all too hastily. Taken compulsorily in large doses it is impossible to digest, but after repeated tastings in small draughts it becomes completely agreeable and even addictive. Whoever possesses a refined sensitivity for artistic manifestations will appreciate that, in the science of histology, there exists an inherent focus of aesthetic emotions.

However far the mathematician’s calculating senses seem to be separated from the audacious flight of the artist’s imagination, these manifestations refer to mere instantaneous images, which have been arbitrarily torn from the operation of both. In designing new theories, the mathematician needs an equally bold and inspired imagination as creative as the artist, and in carrying out the details of a work the artist must unemotionally reckon all the resources necessary for the success of the parts. Common to both is the fabrication, the creation of the structure from the intellect.

I do not conceive of any manifestation of culture, of science, of art, as purposes in themselves. I think the purpose of science and culture is man.

I have long held an opinion, almost amounting to conviction, in common I believe with many other lovers of natural knowledge, that the various forms under which the forces of matter are made manifest have one common origin; or, in other words, are so directly related and mutually dependent, that they are convertible, as it were, one into another, and possess equivalents of power in their action.

In mathematics as in other fields, to find one self lost in wonder at some manifestation is frequently the half of a new discovery.

It appears unlikely that the role of the genes in development is to be understood so long as the genes are considered as dictatorial elements in the cellular economy. It is not enough to know what a gene does when it manifests itself. One must also know the mechanisms determining which of the many gene-controlled potentialities will be realized.

It follows from the theory of relativity that mass and energy are both different manifestations of the same thing—a somewhat unfamiliar conception for the average man. Furthermore E=MC², in which energy is put equal to mass multiplied with the square of the velocity of light, showed that a very small amount of mass may be converted into a very large amount of energy... the mass and energy were in fact equivalent.

It needs scarcely be pointed out that in placing Mathematics at the head of Positive Philosophy, we are only extending the application of the principle which has governed our whole Classification. We are simply carrying back our principle to its first manifestation. Geometrical and Mechanical phenomena are the most general, the most simple, the most abstract of all,— the most irreducible to others, the most independent of them; serving, in fact, as a basis to all others. It follows that the study of them is an indispensable preliminary to that of all others. Therefore must Mathematics hold the first place in the hierarchy of the sciences, and be the point of departure of all Education whether general or special.

Life through many long periods has been manifested in a countless host of varying structures, all circumscribed by one general plan, each appointed to a definite place, and limited to an appointed duration. On the whole the earth has been thus more and more covered by the associated life of plants and animals, filling all habitable space with beings capable of enjoying their own existence or ministering to the enjoyment of others; till finally, after long preparation, a being was created capable of the wonderful power of measuring and weighing all the world of matter and space which surrounds him, of treasuring up the past history of all the forms of life, and considering his own relation to the whole. When he surveys this vast and co-ordinated system, and inquires into its history and origin, can he be at a loss to decide whether it be a work of Divine thought and wisdom, or the fortunate offspring of a few atoms of matter, warmed by the anima mundi, a spark of electricity, or an accidental ray of sunshine?

Mathematics and music, the most sharply contrasted fields of scientific activity which can be found, and yet related, supporting each other, as if to show forth the secret connection which ties together all the activities of our mind, and which leads us to surmise that the manifestations of the artist’s genius are but the unconscious expressions of a mysteriously acting rationality.

My aim is to argue that the universe can come into existence without intervention, and that there is no need to invoke the idea of a Supreme Being in one of its numerous manifestations.

My position is perfectly definite. Gravitation, motion, heat, light, electricity and chemical action are one and the same object in various forms of manifestation.

Our natural way of thinking about these coarser emotions is that the mental perception of some fact excites the mental affection called the emotion, and that this latter state of mind gives rise to the bodily expression. My theory, on the contrary, is that the bodily changes follow directly the perception of the exciting fact, and that our feeling of the same changes as they occur IS the emotion. Common-sense says, we lose our fortune, are sorry and weep; we meet a bear, are frightened and run; we are insulted by a rival, are angry and strike. The hypothesis here to be defended says that this order of sequence is incorrect, that the one mental state is not immediately induced by the other, that the bodily manifestations must first be interposed between, and that the more rational statement is that we feel sorry because we cry, angry because we strike, afraid because we tremble, and not that we cry, strike, or tremble, because we are sorry, angry, or fearful, as the case may be. Without the bodily states following on the perception, the latter would be purely cognitive in form, pale, colorless, destitute of emotional warmth. We might then see the bear, and judge it best to run, receive the insult and deem it right to strike, but we should not actually feel afraid or angry.

PLAGUE, n. Nature's fortuitous manifestation of her purposeless objectionableness.

Psychology, on the other hand, seeks to give account of the interconnexion of processes which are evinced by our own consciousness, or which we infer from such manifestations of the bodily life in other creatures as indicate the presence of a consciousness similar to our own.

The Archetypal idea was manifested in the flesh, under divers such modifications, upon this planet, long prior to the existence of those animal species that actually exemplify it. To what natural laws or secondary causes the orderly succession and progression of such organic phaenomena may have been committed we as yet are ignorant. But if, without derogation of the Divine power, we may conceive the existence of such ministers, and personify them by the term 'Nature,' we learn from the past history of our globe that she has advanced with slow and stately steps, guided by the archetypal light, amidst the wreck of worlds, from the first embodiment of the Vertebrate idea under its old Ichthyic vestment, until it became arrayed in the glorious garb of the Human form.

The beautiful is a manifestation of secret laws of nature, which but for this phenomenon would have remained hidden from us for ever.

The combination of such characters, some, as the sacral ones, altogether peculiar among Reptiles, others borrowed, as it were, from groups now distinct from each other, and all manifested by creatures far surpassing in size the largest of existing reptiles, will, it is presumed, be deemed sufficient ground for establishing a distinct tribe or sub-order of Saurian Reptiles, for which I would propose the name of Dinosauria.

The fairest thing we can experience is the mysterious. It is the fundamental emotion which stands at the cradle of true art and true science. He who knows it not and can no longer wonder, no longer feel amazement, is as good as dead, a snuffed-out candle. It was the experience of mystery–even if mixed with fear–that engendered religion. A knowledge of the existence of something we cannot penetrate, of the manifestations of the profoundest reason and the most radiant beauty, which are only accessible to our reason in their most elementary forms–it is this knowledge and this emotion that constitute the truly religious attitude; in this sense, and in this alone, I am a deeply religious man.

The Grand Cañon of the Colorado is a great innovation in modern ideas of scenery, and in our conceptions of the grandeur, beauty, and power of nature. As with all great innovations it is not to be comprehended in a day or a week, nor even in a month. It must be dwelt upon and studied, and the study must comprise the slow acquisition of the meaning and spirit of that marvelous scenery which characterizes the Plateau Country, and of which the great chasm is the superlative manifestation.

The law of conservation rigidly excludes both creation and annihilation. Waves may change to ripples, and ripples to waves,—magnitude may be substituted for number, and number for magnitude,—asteroids may aggregate to suns, suns may resolve themselves into florae and faunae, and florae and faunae melt in air,—the flux of power is eternally the same. It rolls in music through the ages, and all terrestrial energy,—the manifestations of life, as well as the display of phenomena, are but the modulations of its rhythm.

The scientist who recognizes God knows only the God of Newton. To him the God imagined by Laplace and Comte is wholly inadequate. He feels that God is in nature, that the orderly ways in which nature works are themselves the manifestations of God's will and purpose. Its laws are his orderly way of working.

The universality of parasitism as an offshoot of the predatory habit negatives the position taken by man that it is a pathological phenomenon or a deviation from the normal processes of nature. The pathological manifestations are only incidents in a developing parasitism. As human beings intent on maintaining man's domination over nature we may regard parasitism as pathological insofar as it becomes a drain upon human resources. In our efforts to protect ourselves we may make every kind of sacrifice to limit, reduce, and even eliminate parasitism as a factor in human life. Science attempts to define the terms on which this policy of elimination may or may not succeed. We must first of all thoroughly understand the problem, put ourselves in possession of all the facts in order to estimate the cost. Too often it has been assumed that parasitism was abnormal and that it needed only a slight force to reestablish what was believed to be a normal equilibrium without parasitism. On the contrary, biology teaches us that parasitism is a normal phenomenon and if we accept this view we shall be more ready to pay the price of freedom as a permanent and ever recurring levy of nature for immunity from a condition to which all life is subject. The greatest victory of man over nature in the physical realm would undoubtedly be his own delivery from the heavy encumbrance of parasitism with which all life is burdened.

The universe is an asymmetrical entity. I am inclined to believe that life as it is manifested to us must be a function of the asymmetry of the universe or of the consequence of this fact. The universe is asymmetrical; for if one placed the entire set of bodies that compose the solar system, each moving in its own way, before a mirror, the image shown would not be superimposable on the reality.

Theorem I. The first and most simple manifestation and representation of things, non-existent as well as latent in the folds of Nature, happened by means of straight line and circle.
Theorem II. Yet the circle cannot be artificially produced without the straight line, or the straight line without the point. Hence, things first began to be by way of a point, and a monad. And things related to the periphery (however big they may be) can in no way exist without the aid of the central point.

There is nothing in the world except empty curved space. Matter, charge, electromagnetism, and other fields are only manifestations of the curvature of space.

There is only one subject matter for education, and that is Life in all its manifestations. Instead of this single unity, we offer children—Algebra, from which nothing follows; Geometry, from which nothing follows; Science, from which nothing follows; History, from which nothing follows; a Couple of Languages, never mastered; and lastly, most dreary of all, Literature, represented by plays of Shakespeare, with philological notes and short analyses of plot and character to be in substance committed to memory.

There is the immense sea of energy ... a multidimensional implicate order, ... the entire universe of matter as we generally observe it is to be treated as a comparatively small pattern of excitation. This excitation pattern is relatively autonomous and gives rise to approximately recurrent, stable separable projections into a three-dimensional explicate order of manifestation, which is more or less equivalent to that of space as we commonly experience it.

This new force, which was unknown until now, is common to organic and inorganic nature. I do not believe that this is a force entirely independent of the electrochemical affinities of matter; I believe, on the contrary, that it is only a new manifestation, but since we cannot see their connection and mutual dependence, it will be easier to designate it by a separate name. I will call this force catalytic force. Similarly, I will call the decomposition of bodies by this force catalysis, as one designates the decomposition of bodies by chemical affinity analysis.

To Nature nothing can be added; from Nature nothing can be taken away; the sum of her energies is constant, and the utmost man can do in the pursuit of physical truth, or in the applications of physical knowledge, is to shift the constituents of the never-varying total. The law of conservation rigidly excludes both creation and annihilation. Waves may change to ripples, and ripples to waves; magnitude may be substituted for number, and number for magnitude; asteroids may aggregate to suns, suns may resolve themselves into florae and faunae, and floras and faunas melt in air: the flux of power is eternally the same. It rolls in music through the ages, and all terrestrial energy—the manifestations of life as well as the display of phenomena—are but the modulations of its rhythm.

Today every city, town, or village is affected by it. We have entered the Neon Civilization and become a plastic world.. It goes deeper than its visual manifestations, it affects moral matters; we are engaged, as astrophysicists would say, on a decaying orbit.

Very few, even among those who have taken the keenest interest in the progress of the revolution in natural knowledge set afoot by the publication of the “Origin of Species”; and who have watched, not without astonishment, the rapid and complete change which has been effected both inside and outside the boundaries of the scientific world in the attitude of men’s minds towards the doctrines which are expounded in that great work, can have been prepared for the extraordinary manifestation of affectionate regard for the man, and of profound reverence for the philosopher, which followed the announcement, on Thursday last, of the death of Mr Darwin.

We are a spectacular, splendid manifestation of life. We have language… We have affection. We have genes for usefulness, and usefulness is about as close to a “common goal” for all of nature as I can guess at.

We are not alone in the universe, and do not bear alone the whole burden of life and what comes of it. Life is a cosmic event—so far as we know the most complex state of organization that matter has achieved in our cosmos. It has come many times, in many places—places closed off from us by impenetrable distances, probably never to be crossed even with a signal. As men we can attempt to understand it, and even somewhat to control and guide its local manifestations. On this planet that is our home, we have every reason to wish it well. Yet should we fail, all is not lost. Our kind will try again elsewhere.

We are not to suppose, that there is any violent exertion of power, such as is required in order to produce a great event in little time; in nature, we find no deficiency in respect of time, nor any limitation with regard to power. But time is not made to flow in vain; nor does there ever appear the exertion of superfluous power, or the manifestation of design, not calculated in wisdom to effect some general end.

We are the generation that searched on Mars for evidence of life, but couldn’t rouse enough moral sense to stop the destruction of even the grandest manifestations of life on earth. In that sense, we are like the Romans whose works of an, architecture, and engineering inspire our awe but whose traffic in slaves and gladiatorial combat is mystifying and loathsome.
[Co-author with Anna Sequoia.]

We come no nearer the infinitude of the creative power of God, if we enclose the space of its revelation within a sphere described with the radius of the Milky Way, than if we were to limit it to a ball an inch in diameter. All that is finite, whatever has limits and a definite relation to unity, is equally far removed from the infinite... Eternity is not sufficient to embrace the manifestations of the Supreme Being, if it is not combined with the infinitude of space.

We may be sure, that if Lyell were now living he would frankly recognize new facts, as soon as they were established, and would not shrink from any modification of his theory which these might demand. Great as were his services to geology, this, perhaps, is even greater—for the lesson applies to all sciences and to all seekers alter knowledge—that his career, from first to lost, was the manifestation of a judicial mind, of a noble spirit, raised far above all party passions and petty considerations, of an intellect great in itself, but greater still in its grand humility; that he was a man to whom truth was as the “pearl of price,” worthy of the devotion and, if need be, the sacrifice of a life.

What is the use of this history, what the use of all this minute research? I well know that it will not produce a fall in the price of pepper, a rise in that of crates of rotten cabbages, or other serious events of this kind, which cause fleets to be manned and set people face to face intent upon one another's extermination. The insect does not aim at so much glory. It confines itself to showing us life in the inexhaustible variety of its manifestations; it helps us to decipher in some small measure the obscurest book of all, the book of ourselves.

Whatever Nature undertakes, she can only accomplish it in a sequence. She never makes a leap. For example she could not produce a horse if it were not preceded by all the other animals on which she ascends to the horse’s structure as if on the rungs of a ladder. Thus every one thing exists for the sake of all things and all for the sake of one; for the one is of course the all as well. Nature, despite her seeming diversity, is always a unity, a whole; and thus, when she manifests herself in any part of that whole, the rest must serve as a basis for that particular manifestation, and the latter must have a relationship to the rest of the system.

When science, art, literature, and philosophy are simply the manifestation of personality, they are on a level where glorious and dazzling achievements are possible, which can make a man’s name live for thousands of years. But above this level, far above, separated by an abyss, is the level where the highest things are achieved. These things are essentially anonymous.