All men hate the wretched; how, then, must I be hated, who am miserable beyond all living things! Yet you, my creator, detest and spurn me, thy creature, to whom thou are bound by ties only dissoluble by the annihilation of one of us.

But if any skillful minister of nature shall apply force to matter, and by design torture and vex it, in order to [effect] its annihilation, it, on the contrary being brought under this necessity, changes and transforms itself into a strange variety of shapes and appearances; for nothing but the power of the Creator can annihilate, or truly destroy it.

But the World being once fram’d, and the course of Nature establish’d, the Naturalist, (except in some few cases, where God, or Incorporeal Agents interpose), has recourse to the first Cause but for its general and ordinary Support and Influence, whereby it preserves Matter and Motion from Annihilation or Desition; and in explicating particular phenomena, considers onely the Size, Shape, Motion, (or want of it) Texture, and the resulting Qualities and Attributes of the small particles of Matter.

But we have reason to think that the annihilation of work is no less a physical impossibility than its creation, that is, than perpetual motion.

Nature abhors a vacuum. It is quite certain that in the bounds of nature, a vacuum, which is nothing, can find no place. There is no power in Nature from which nothing could have made the universe, and none which could reduce the universe to nothing: that requires the same virtue. Now the matter would be otherwise if there could be a vacuum. For if it could be here, it could also be there; and being here and there, why not elsewhere? and why not everywhere? Thus the universe could reach annihilation by its own forces; but to Him alone who could make it is due the glory of compassing its destruction.

Nevertheless if any skillful Servant of Nature shall bring force to bear on matter, and shall vex it and drive it to extremities as if with the purpose of reducing it to nothing, then will matter (since annihilation or true destruction is not possible except by the omnipotence of God) finding itself in these straits, turn and transform itself into strange shapes, passing from one change to another till it has gone through the whole circle and finished the period.

One would have to have been brought up in the “spirit of militarism” to understand the difference between Hiroshima and Nagasaki on the one hand, and Auschwitz and Belsen on the other. The usual reasoning is the following: the former case is one of warfare, the latter of cold-blooded slaughter. But the plain truth is that the people involved are in both instances nonparticipants, defenseless old people, women, and children, whose annihilation is supposed to achieve some political or military objective.… I am certain that the human race is doomed, unless its instinctive detestation of atrocities gains the upper hand over the artificially constructed judgment of reason.

Our national policies will not be revoked or modified, even for scientists. If the dismissal of Jewish scientists means the annihilation of contemporary German science, then we shall do without science for a few years.
Reply to Max Planck (President of the Kaiser Wilhelm Society for the Advancement of Science) when he tried to petition the Fuhrer to stop the dismissal of scientists on political grounds.

The law of conservation rigidly excludes both creation and annihilation. Waves may change to ripples, and ripples to waves,—magnitude may be substituted for number, and number for magnitude,—asteroids may aggregate to suns, suns may resolve themselves into florae and faunae, and florae and faunae melt in air,—the flux of power is eternally the same. It rolls in music through the ages, and all terrestrial energy,—the manifestations of life, as well as the display of phenomena, are but the modulations of its rhythm.

The tendency of modern physics is to resolve the whole material universe into waves, and nothing but waves. These waves are of two kinds: bottled-up waves, which we call matter, and unbottled waves, which we call radiation or light. If annihilation of matter occurs, the process is merely that of unbottling imprisoned wave-energy and setting it free to travel through space. These concepts reduce the whole universe to a world of light, potential or existent, so that the whole story of its creation can be told with perfect accuracy and completeness in the six words: 'God said, Let there be light'.

There is no consumption, unless that which is lost by one body passes into another. Explanation. In nature there is no annihilation; and therefore the thing which is consumed either passes into the air, or is received into some adjacent body.

There is nothing more certain in nature than that it is impossible for any body to be utterly annihilated.
[Stating the conservation of matter.]

These machines [used in the defense of the Syracusans against the Romans under Marcellus] he [Archimedes] had designed and contrived, not as matters of any importance, but as mere amusements in geometry; in compliance with king Hiero’s desire and request, some time before, that he should reduce to practice some part of his admirable speculation in science, and by accommodating the theoretic truth to sensation and ordinary use, bring it more within the appreciation of people in general. Eudoxus and Archytas had been the first originators of this far-famed and highly-prized art of mechanics, which they employed as an elegant illustration of geometrical truths, and as means of sustaining experimentally, to the satisfaction of the senses, conclusions too intricate for proof by words and diagrams. As, for example, to solve the problem, so often required in constructing geometrical figures, given the two extremes, to find the two mean lines of a proportion, both these mathematicians had recourse to the aid of instruments, adapting to their purpose certain curves and sections of lines. But what with Plato’s indignation at it, and his invectives against it as the mere corruption and annihilation of the one good of geometry,—which was thus shamefully turning its back upon the unembodied objects of pure intelligence to recur to sensation, and to ask help (not to be obtained without base supervisions and depravation) from matter; so it was that mechanics came to be separated from geometry, and, repudiated and neglected by philosophers, took its place as a military art.

To Nature nothing can be added; from Nature nothing can be taken away; the sum of her energies is constant, and the utmost man can do in the pursuit of physical truth, or in the applications of physical knowledge, is to shift the constituents of the never-varying total. The law of conservation rigidly excludes both creation and annihilation. Waves may change to ripples, and ripples to waves; magnitude may be substituted for number, and number for magnitude; asteroids may aggregate to suns, suns may resolve themselves into florae and faunae, and floras and faunas melt in air: the flux of power is eternally the same. It rolls in music through the ages, and all terrestrial energy—the manifestations of life as well as the display of phenomena—are but the modulations of its rhythm.

We scientists, whose tragic destiny it has been to help make the methods of annihilation ever more gruesome and more effective, must consider it our solemn and transcendent duty to do all in our power to prevent these weapons from being used for the brutal purpose for which they were invented.