... [I]nfectious disease is merely a disagreeable instance of a widely prevalent tendency of all living creatures to save themselves the bother of building, by their own efforts, the things they require. Whenever they find it possible to take advantage of the constructive labors of others, this is the path of least resistance. The plant does the work with its roots and its green leaves. The cow eats the plant. Man eats both of them; and bacteria (or investment bankers) eat the man. ...

... I left Caen, where I was living, to go on a geologic excursion under the auspices of the School of Mines. The incidents of the travel made me forget my mathematical work. Having reached Coutances, we entered an omnibus to go to some place or other. At the moment when I put my foot on the step, the idea came to me, without anything in my former thoughts seeming to have paved the way for it, that the transformations I had used to define the Fuchsian functions were identical with those of non-Eudidean geometry. I did not verify the idea; I should not have had time, as upon taking my seat in the omnibus, I went on with a conversation already commenced, but I felt a perfect certainty. On my return to Caen, for convenience sake, I verified the result at my leisure.

...[T]he natural history of the rat is tragically similar to that of man ... some of the more obvious qualities in which rats resemble men — ferocity, omnivorousness, and adaptability to all climates ... the irresponsible fecundity with which both species breed at all seasons of the year with a heedlessness of consequences, which subjects them to wholesale disaster on the inevitable, occasional failure of the food supply.... [G]radually, these two have spread across the earth, keeping pace with each other and unable to destroy each other, though continually hostile. They have wandered from East to West, driven by their physical needs, and — unlike any other species of living things — have made war upon their own kind. The gradual, relentless, progressive extermination of the black rat by the brown has no parallel in nature so close as that of the similar extermination of one race of man by another...

...the life of the planet began the long, slow process of modulating and regulating the physical conditions of the planet. The oxygen in today's atmosphere is almost entirely the result of photosynthetic living, which had its start with the appearance of blue-green algae among the microorganisms.

...travel is more than the seeing of sights; it is a change that goes on, deep and permanent, in the ideas of living.

‘Be not afraid of life. Believe that life is worth living, and your belief will help create the fact.

“Wu Li” was more than poetic. It was the best definition of physics that the conference would produce. It caught that certain something, that living quality that we were seeking to express in a book, that thing without which physics becomes sterile. “Wu” can mean either “matter” or “energy.” “Li” is a richly poetic word. It means “universal order” or “universal law.” It also means “organic patterns.” The grain in a panel of wood is Li. The organic pattern on the surface of a leaf is also Li, and so is the texture of a rose petal. In short, Wu Li, the Chinese word for physics, means “patterns of organic energy” (“matter/ energy” [Wu] + “universal order/organic patterns” [Li]). This is remarkable since it reflects a world view which the founders of western science (Galileo and Newton) simply did not comprehend, but toward which virtually every physical theory of import in the twentieth century is pointing!

[Beyond natural history] Other biological sciences take up the study at other levels of organization: dissecting the individual into organs and tissues and seeing how these work together, as in physiology; reaching down still further to the level of cells, as in cytology; and reaching the final biological level with the study of living molecules and their interactions, as in biochemistry. No one of these levels can be considered as more important than any other.

[Engineering] is a great profession. There is the fascination of watching a figment of the imagination emerge through the aid of science to a plan on paper. Then it moves to realization in stone or metal or energy. Then it brings homes to men or women. Then it elevates the standards of living and adds to the comforts of life. That is the engineer’s high privilege.

[For] men to whom nothing seems great but reason ... nature ... is a cosmos, so admirable, that to penetrate to its ways seems to them the only thing that makes life worth living. These are the men whom we see possessed by a passion to learn ... Those are the natural scientific men; and they are the only men that have any real success in scientific research.

[In an inventor’s life] Everything is stacked against you, but for some reason some silly chaps seem to be driven to it (rather like a painter of a composer of music), which is perhaps just as well or we should still be living in the Stone Age.

[On common water.] Its substance reaches everywhere; it touches the past and prepares the future; it moves under the poles and wanders thinly in the heights of air. It can assume forms of exquisite perfection in a snowflake, or strip the living to a single shining bone cast up by the sea.

[Other than fossils,] the most important of these other records of creation is, without doubt, ontogeny, that is, the history of the developmment of the organic individual (embryology and motamorphology). It briefly repeats in great and marked features the series of forms which the ancestors of the respective individuals have passed through from the beginning of their tribe. We have designated the palaeontological history of the development of the ancestors of a living form as the history of a tribe, or phylogeny, and we may therefore thus enunciate this exceedingly important biogenetic fundamental principle: “Ontogeny is a short and quick repetition, or recapitulation, of Phylogeny, determined by the laws of Inheritance and Adaptation.”

[The center must be more than just] old junk in a box. [It must be a] living dynamic thing to attract people to public service at all levels.

Ode to The Amoeba
Recall from Time's abysmal chasm
That piece of primal protoplasm
The First Amoeba, strangely splendid,
From whom we're all of us descended.
That First Amoeba, weirdly clever,
Exists today and shall forever,
Because he reproduced by fission;
He split himself, and each division
And subdivision deemed it fitting
To keep on splitting, splitting, splitting;
So, whatsoe'er their billions be,
All, all amoebas still are he.
Zoologists discern his features
In every sort of breathing creatures,
Since all of every living species,
No matter how their breed increases
Or how their ranks have been recruited,
From him alone were evoluted.
King Solomon, the Queen of Sheba
And Hoover sprang from that amoeba;
Columbus, Shakespeare, Darwin, Shelley
Derived from that same bit of jelly.
So famed is he and well-connected,
His statue ought to be erected,
For you and I and William Beebe
Are undeniably amoebae!

The Redwoods

Here, sown by the Creator's hand,
In serried ranks, the Redwoods stand;
No other clime is honored so,
No other lands their glory know.

The greatest of Earth's living forms,
Tall conquerors that laugh at storms;
Their challenge still unanswered rings,
Through fifty centuries of kings.

The nations that with them were young,
Rich empires, with their forts far-flung,
Lie buried now—their splendor gone;
But these proud monarchs still live on.

So shall they live, when ends our day,
When our crude citadels decay;
For brief the years allotted man,
But infinite perennials' span.

This is their temple, vaulted high,
And here we pause with reverent eye,
With silent tongue and awe-struck soul;
For here we sense life's proper goal;

To be like these, straight, true and fine,
To make our world, like theirs, a shrine;
Sink down, oh traveler, on your knees,
God stands before you in these trees.

Eine brennendste Zeitfrage allerdings! Es brennt in allen Ecken und Enden der ethnologischen Welt, brennt hell, lichterloh, in vollster Brunst, es brennt ringsum, Gross Feuer! und Niemand regt eine Hand.
A most burning question of time, though. It burns in every nook and cranny of the ethnological world, burning, bright, brightly, in the fullest blaze, and it burns all around, huge fire! and no one lifts a hand.
[Expressing his desperation over the loss of the cultural memory of ethnic traditions as so many cultures were no longer living in isolation.]

Le savant n’étudie pas la nature parce que cela est utile; il l’étudie parce qu’il y prend plaisir et il y prend plaisir parce qu’elle est belle. Si la nature n’était pas belle, elle ne vaudrait pas la peine d’être connue, la vie ne vaudrait pas la peine d’être vécue.
The scientist does not study nature because it is useful to do so. He studies it because he takes pleasure in it, and he takes pleasure in it because it is beautiful. If nature were not beautiful, it would not be worth knowing, and life would not be worth living. I am not speaking, of course, of the beauty which strikes the senses, of the beauty of qualities and appearances. I am far from despising this, but it has nothing to do with science. What I mean is that more intimate beauty which comes from the harmonious order of its parts, and which a pure intelligence can grasp.

Mi è impossibile cingere i fianchi di una ragazza con il mio braccio destro e serrare il suo sorriso nella mia mano sinistra, per poi tentare di studiare i due oggetti separatamente. Allo stesso modo, non ci è possibile separare la vita dalla materia vivente, allo scopo di studiare la sola materia vivente e le sue reazioni. Inevitabilmente, studiando la materia vivente e le sue reazioni, studiamo la vita stessa.
It is impossible to encircle the hips of a girl with my right arm and hold her smile in my left hand, then proceed to study the two items separately. Similarly, we can not separate life from living matter, in order to study only living matter and its reactions. Inevitably, studying living matter and its reactions, we study life itself

A cell has a history; its structure is inherited, it grows, divides, and, as in the embryo of higher animals, the products of division differentiate on complex lines. Living cells, moreover, transmit all that is involved in their complex heredity. I am far from maintaining that these fundamental properties may not depend upon organisation at levels above any chemical level; to understand them may even call for different methods of thought; I do not pretend to know. But if there be a hierarchy of levels we must recognise each one, and the physical and chemical level which, I would again say, may be the level of self-maintenance, must always have a place in any ultimate complete description.

A chemical compound once formed would persist for ever, if no alteration took place in surrounding conditions. But to the student of Life the aspect of nature is reversed. Here, incessant, and, so far as we know, spontaneous change is the rule, rest the exception—the anomaly to be accounted for. Living things have no inertia and tend to no equilibrium.

A huge net is being dragged across the sea floor, destroying everything in its path. Ahead of it bloom undersea forests and their hundreds and thousands of living creatures, both plant and animal; behind it is a desert. The net is pulled to the surface and most of the dead and dying life forms in it are thrown out. A few marketable species are retained. [Trawling] is like taking a front-end loader and scraping up your entire front garden and shredding it, keeping a few pebbles, and dumping the rest of it down the drain.

A human being is part of the whole, called by us “Universe”; a part limited in time and space. He experiences himself, his thoughts and feelings as something separated from the rest—a kind of optical delusion of his consciousness. This delusion is a kind of prison for us, restricting us to our personal desires and to affection for a few persons nearest us. Our task must be to free ourselves from this prison by widening our circle of compassion to embrace all living creatures and the whole of nature in its beauty. Nobody is able to achieve this completely but the striving for such achievement is, in itself, a part of the liberation and a foundation for inner security.

A hundred times every day I remind myself that my inner and outer life depends on the labors of other men, living and dead, and that I must exert myself in order to give in the measure as I have received and am still receiving.

A living civilization creates; a dying, builds museums.

A living organism must be studied from two distinct aspects. One of these is the causal-analytic aspect which is so fruitfully applicable to ontogeny. The other is the historical descriptive aspect which is unravelling lines of phylogeny with ever-increasing precision. Each of these aspects may make suggestions concerning the possible significance of events seen under the other, but does not explain or translate them into simpler terms.

A living speck—the merest dab of life—capable of pleasure and pain, is far more interesting to me than all the immensities of mere matter.

A lodestone is a wonderful thing in very many experiments, and like living things. And one of its remarkable virtues in that which the ancients considered to be a living soul in the sky, in the globes and in the stars, in the sun and in the moon.

A mineralogist is the only living creature who belongs in the mineral kingdom.

A noble, logical diagram once recorded will never die, but long after we are gone be a living thing, asserting itself with ever-growing insistency. Remember that our sons and our grandsons are going to do things that would stagger us.

A quarter-horse jockey learns to think of a twenty-second race as if it were occurring across twenty minutes—in distinct parts, spaced in his consciousness. Each nuance of the ride comes to him as he builds his race. If you can do the opposite with deep time, living in it and thinking in it until the large numbers settle into place, you can sense how swiftly the initial earth packed itself together, how swiftly continents have assembled and come apart, how far and rapidly continents travel, how quickly mountains rise and how quickly they disintegrate and disappear.

A soil adapted to the growth of plants, is necessarily prepared and carefully preserved; and, in the necessary waste of land which is inhabited, the foundation is laid for future continents, in order to support the system of the living world.

A sound Physics of the Earth should include all the primary considerations of the earth's atmosphere, of the characteristics and continual changes of the earth's external crust, and finally of the origin and development of living organisms. These considerations naturally divide the physics of the earth into three essential parts, the first being a theory of the atmosphere, or Meteorology, the second, a theory of the earth's external crust, or Hydrogeology, and the third, a theory of living organisms, or Biology.

A strict materialist believes that everything depends on the motion of matter. He knows the form of the laws of motion though he does not know all their consequences when applied to systems of unknown complexity.
Now one thing in which the materialist (fortified with dynamical knowledge) believes is that if every motion great & small were accurately reversed, and the world left to itself again, everything would happen backwards the fresh water would collect out of the sea and run up the rivers and finally fly up to the clouds in drops which would extract heat from the air and evaporate and afterwards in condensing would shoot out rays of light to the sun and so on. Of course all living things would regrede from the grave to the cradle and we should have a memory of the future but not of the past.
The reason why we do not expect anything of this kind to take place at any time is our experience of irreversible processes, all of one kind, and this leads to the doctrine of a beginning & an end instead of cyclical progression for ever.

A vital phenomenon can only be regarded as explained if it has been proven that it appears as the result of the material components of living organisms interacting according to the laws which those same components follow in their interactions outside of living systems.

A word is not a crystal, transparent and unchanged, it is the skin of a living thought and may vary greatly in color and content according to the circumstances and the time in which it is used.

About two million years ago, man appeared. He has become the dominant species on the earth. All other living things, animal and plant, live by his sufferance. He is the custodian of life on earth, and in the solar system. It’s a big responsibility.

ADDER, n. A species of snake. So called from its habit of adding funeral outlays to the other expenses of living.

After having produced aquatic animals of all ranks and having caused extensive variations in them by the different environments provided by the waters, nature led them little by little to the habit of living in the air, first by the water's edge and afterwards on all the dry parts of the globe. These animals have in course of time been profoundly altered by such novel conditions; which so greatly influenced their habits and organs that the regular gradation which they should have exhibited in complexity of organisation is often scarcely recognisable.

All fossil anthropoids found hitherto have been known only from mandibular or maxillary fragments, so far as crania are concerned, and so the general appearance of the types they represented had been unknown; consequently, a condition of affairs where virtually the whole face and lower jaw, replete with teeth, together with the major portion of the brain pattern, have been preserved, constitutes a specimen of unusual value in fossil anthropoid discovery. Here, as in Homo rhodesiensis, Southern Africa has provided documents of higher primate evolution that are amongst the most complete extant. Apart from this evidential completeness, the specimen is of importance because it exhibits an extinct race of apes intermediate between living anthropoids and man ... Whether our present fossil is to be correlated with the discoveries made in India is not yet apparent; that question can only be solved by a careful comparison of the permanent molar teeth from both localities. It is obvious, meanwhile, that it represents a fossil group distinctly advanced beyond living anthropoids in those two dominantly human characters of facial and dental recession on one hand, and improved quality of the brain on the other. Unlike Pithecanthropus, it does not represent an ape-like man, a caricature of precocious hominid failure, but a creature well advanced beyond modern anthropoids in just those characters, facial and cerebral, which are to be anticipated in an extinct link between man and his simian ancestor. At the same time, it is equally evident that a creature with anthropoid brain capacity and lacking the distinctive, localised temporal expansions which appear to be concomitant with and necessary to articulate man, is no true man. It is therefore logically regarded as a man-like ape. I propose tentatively, then, that a new family of Homo-simidæ be created for the reception of the group of individuals which it represents, and that the first known species of the group be designated Australopithecus africanus, in commemoration, first, of the extreme southern and unexpected horizon of its discovery, and secondly, of the continent in which so many new and important discoveries connected with the early history of man have recently been made, thus vindicating the Darwinian claim that Africa would prove to be the cradle of mankind.

All infections, of whatever type, with no exceptions, are products of parasitic beings; that is, by living organisms that enter in other living organisms, in which they find nourishment, that is, food that suits them, here they hatch, grow and reproduce themselves.

All known living bodies are sharply divided into two special kingdoms, based upon the essential differences which distinguish animals from plants, and in spite of what has been said, I am convinced that these two kingdoms do not really merge into one another at any point.

All living forms are the results of physical influences which are still in operation, and vary only in degree and direction

All living organisms are but leaves on the same tree of life. The various functions of plants and animals and their specialized organs are manifestations of the same living matter. This adapts itself to different jobs and circumstances, but operates on the same basic principles. Muscle contraction is only one of these adaptations. In principle it would not matter whether we studied nerve, kidney or muscle to understand the basic principles of life. In practice, however, it matters a great deal.

All living things need their instruction manual (even nonliving things like viruses) and that is all they need, carried in one very small suitcase.

All men hate the wretched; how, then, must I be hated, who am miserable beyond all living things! Yet you, my creator, detest and spurn me, thy creature, to whom thou are bound by ties only dissoluble by the annihilation of one of us.

All the different classes of beings which taken together make up the universe are, in the ideas of God who knows distinctly their essential gradations, only so many ordinates of a single curve so closely united that it would be impossible to place others between any two of them, since that would imply disorder and imperfection. Thus men are linked with the animals, these with the plants and these with the fossils which in turn merge with those bodies which our senses and our imagination represent to us as absolutely inanimate. And, since the law of continuity requires that when the essential attributes of one being approximate those of another all the properties of the one must likewise gradually approximate those of the other, it is necessary that all the orders of natural beings form but a single chain, in which the various classes, like so many rings, are so closely linked one to another that it is impossible for the senses or the imagination to determine precisely the point at which one ends and the next begins?all the species which, so to say, lie near the borderlands being equivocal, at endowed with characters which might equally well be assigned to either of the neighboring species. Thus there is nothing monstrous in the existence zoophytes, or plant-animals, as Budaeus calls them; on the contrary, it is wholly in keeping with the order of nature that they should exist. And so great is the force of the principle of continuity, to my thinking, that not only should I not be surprised to hear that such beings had been discovered?creatures which in some of their properties, such as nutrition or reproduction, might pass equally well for animals or for plants, and which thus overturn the current laws based upon the supposition of a perfect and absolute separation of the different orders of coexistent beings which fill the universe;?not only, I say, should I not be surprised to hear that they had been discovered, but, in fact, I am convinced that there must be such creatures, and that natural history will perhaps some day become acquainted with them, when it has further studied that infinity of living things whose small size conceals them for ordinary observation and which are hidden in the bowels of the earth and the depth of the sea.

America has always been greatest when we dared to be great. We can reach for greatness again. We can follow our dreams to distant stars, living and working in space for peaceful, economic, and scientific gain. Tonight, I am directing NASA to develop a permanently manned space station and to do it within a decade.

An article in Bioscience in November 1987 by Julie Ann Miller claimed the cortex was a “quarter-meter square.” That is napkin-sized, about ten inches by ten inches. Scientific American magazine in September 1992 upped the ante considerably with an estimate of 1½ square meters; that’s a square of brain forty inches on each side, getting close to the card-table estimate. A psychologist at the University of Toronto figured it would cover the floor of his living room (I haven’t seen his living room), but the prize winning estimate so far is from the British magazine New Scientist’s poster of the brain published in 1993 which claimed that the cerebral cortex, if flattened out, would cover a tennis court. How can there be such disagreement? How can so many experts not know how big the cortex is? I don’t know, but I’m on the hunt for an expert who will say the cortex, when fully spread out, will cover a football field. A Canadian football field.

An attempt to study the evolution of living organisms without reference to cytology would be as futile as an account of stellar evolution which ignored spectroscopy.

An example of such emergent phenomena is the origin of life from non-living chemical compounds in the oldest, lifeless oceans of the earth. Here, aided by the radiation energy received from the sun, countless chemical materials were synthesized and accumulated in such a way that they constituted, as it were, a primeval “soup.” In this primeval soup, by infinite variations of lifeless growth and decay of substances during some billions of years, the way of life was ultimately reached, with its metabolism characterized by selective assimilation and dissimilation as end stations of a sluiced and canalized flow of free chemical energy.

An Individual, whatever species it might be, is nothing in the Universe. A hundred, a thousand individuals are still nothing. The species are the only creatures of Nature, perpetual creatures, as old and as permanent as it. In order to judge it better, we no longer consider the species as a collection or as a series of similar individuals, but as a whole independent of number, independent of time, a whole always living, always the same, a whole which has been counted as one in the works of creation, and which, as a consequence, makes only a unity in Nature.

And for rejecting such a Medium, we have the Authority of those the oldest and most celebrated Philosophers of Greece and Phoenicia, who made a Vacuum, and Atoms, and the Gravity of Atoms, the first Principles of their Philosophy; tacitly attributing Gravity to some other Cause than dense Matter. Later Philosophers banish the Consideration of such a Cause out of natural Philosophy, feigning Hypotheses for explaining all things mechanically, and referring other Causes to Metaphysicks: Whereas the main Business of natural Philosophy is to argue from Phaenomena without feigning Hypotheses, and to deduce Causes from Effects, till we come to the very first Cause, which certainly is not mechanical; and not only to unfold the Mechanism of the World, but chiefly to resolve these and such like Questions. What is there in places almost empty of Matter, and whence is it that the Sun and Planets gravitate towards one another, without dense Matter between them? Whence is it that Nature doth nothing in vain; and whence arises all that Order and Beauty which we see in the World? ... does it not appear from phaenomena that there is a Being incorporeal, living, intelligent, omnipresent, who in infinite space, as it were in his Sensory, sees the things themselves intimately, and thoroughly perceives them, and comprehends them wholly by their immediate presence to himself.

And from true lordship it follows that the true God is living, intelligent, and powerful; from the other perfections, that he is supreme, or supremely perfect. He is eternal and infinite, omnipotent and omniscient; that is, he endures from eternity to eternity; and he is present from infinity to infinity; he rules all things, and he knows all things that happen or can happen.

And God said, Let the earth bring forth the living creature after his kind, cattle, and creeping thing, and beast of the earth after his kind: and it was so.

And having thus passed the principles of arithmetic, geometry, astronomy, and geography, with a general compact of physics, they may descend in mathematics to the instrumental science of trigonometry, and from thence to fortification, architecture, engineering, or navigation. And in natural philosophy they may proceed leisurely from the history of meteors, minerals, plants, and living creatures, as far as anatomy. Then also in course might be read to them out of some not tedious writer the institution of physic. … To set forward all these proceedings in nature and mathematics, what hinders but that they may procure, as oft as shall be needful, the helpful experiences of hunters, fowlers, fishermen, shepherds, gardeners, apothecaries; and in other sciences, architects, engineers, mariners, anatomists.

And now, as a germination of planetary dimensions, comes the thinking layer which over its full extent develops and intertwines its fibres, not to confuse and neutralise them but to reinforce them in the living unity of a single tissue.

And of every living thing of all flesh, you shall bring two of every sort into the ark, to keep them alive with you; they shall be male and female. Of the birds according to their kinds, and of the animals according to their kinds, of every creeping thing of the ground according to its kind.

And so the great truth, now a paradox, may become a commonplace, that man is greater than his surroundings, and that the production of a breed of men and women, even in our great cities, less prone to disease, and pain, more noble in aspect, more rational in habits, more exultant in the pure joy of living, is not only scientifically possible, but that even the partial fulfillment of this dream, if dream it be, is the most worthy object towards which the lover of his kind can devote the best energies of his life.

Anthropology has reached that point of development where the careful investigation of facts shakes our firm belief in the far-reaching theories that have been built up. The complexity of each phenomenon dawns on our minds, and makes us desirous of proceeding more cautiously. Heretofore we have seen the features common to all human thought. Now we begin to see their differences. We recognize that these are no less important than their similarities, and the value of detailed studies becomes apparent. Our aim has not changed, but our method must change. We are still searching for the laws that govern the growth of human culture, of human thought; but we recognize the fact that before we seek for what is common to all culture, we must analyze each culture by careful and exact methods, as the geologist analyzes the succession and order of deposits, as the biologist examines the forms of living matter. We see that the growth of human culture manifests itself in the growth of each special culture. Thus we have come to understand that before we can build up the theory of the growth of all human culture, we must know the growth of cultures that we find here and there among the most primitive tribes of the Arctic, of the deserts of Australia, and of the impenetrable forests of South America; and the progress of the civilization of antiquity and of our own times. We must, so far as we can, reconstruct the actual history of mankind, before we can hope to discover the laws underlying that history.

Any living cell carries with it the experience of a billion years of experimentation by its ancestors. (1949)

Anybody who looks at living organisms knows perfectly well that they can produce other organisms like themselves. This is their normal function, they wouldn’t exist if they didn’t do this, and it’s not plausible that this is the reason why they abound in the world. In other words, living organisms are very complicated aggregations of elementary parts, and by any reasonable theory of probability or thermodynamics highly improbable. That they should occur in the world at all is a miracle of the first magnitude; the only thing which removes, or mitigates, this miracle is that they reproduce themselves. Therefore, if by any peculiar accident there should ever be one of them, from there on the rules of probability do not apply, and there will be many of them, at least if the milieu is reasonable. But a reasonable milieu is already a thermodynamically much less improbable thing. So, the operations of probability somehow leave a loophole at this point, and it is by the process of self-reproduction that they are pierced.

Art and religion are not professions: they are not occupations for which men can be paid. The artist and the saint do what they have to do, not to make a living, but in obedience to some mysterious necessity. They do not product to live - they live to produce.

As a progressive discipline [biochemistry] belongs to the present century. From the experimental physiologists of the last century it obtained a charter, and, from a few pioneers of its own, a promise of success; but for the furtherance of its essential aim that century left it but a small inheritance of facts and methods. By its essential or ultimate aim I myself mean an adequate and acceptable description of molecular dynamics in living cells and tissues.

As geologists, we learn that it is not only the present condition of the globe that has been suited to the accommodation of myriads of living creatures, but that many former states also have been equally adapted to the organization and habits of prior races of beings. The disposition of the seas, continents, and islands, and the climates have varied; so it appears that the species have been changed, and yet they have all been so modelled, on types analogous to those of existing plants and animals, as to indicate throughout a perfect harmony of design and unity of purpose. To assume that the evidence of the beginning or end of so vast a scheme lies within the reach of our philosophical inquiries, or even of our speculations, appears to us inconsistent with a just estimate of the relations which subsist between the finite powers of man and the attributes of an Infinite and Eternal Being.

As long as museums and universities send out expeditions to bring to light new forms of living and extinct animals and new data illustrating the interrelations of organisms and their environments, as long as anatomists desire a broad comparative basis human for anatomy, as long as even a few students feel a strong curiosity to learn about the course of evolution and relationships of animals, the old problems of taxonomy, phylogeny and evolution will gradually reassert themselves even in competition with brilliant and highly fruitful laboratory studies in cytology, genetics and physiological chemistry.

As physicists have arranged an extensive series of effects under the general term of Heat, so they have named another series Light, and a third they have called Electricity. We find ... that all these principles are capable of being produced through the medium of living bodies, for nearly all animals have the power of evolving heat; many insects, moreover, can voluntarily emit light; and the property of producing electricity is well evinced in the terrible shock of the electric eel, as well as in that of some other creatures. We are indeed in the habit of talking of the Electric fluid, or the Galvanic fluid, but this in reality is nothing but a licence of expression suitable to our finite and material notions.

As scientific men we have all, no doubt, felt that our fellow men have become more and more satisfying as fish have taken up their work which has been put often to base uses, which must lead to disaster. But what sin is to the moralist and crime to the jurist so to the scientific man is ignorance. On our plane, knowledge and ignorance are the immemorial adversaries. Scientific men can hardly escape the charge of ignorance with regard to the precise effect of the impact of modern science upon the mode of living of the people and upon their civilisation. For them, such a charge is worse than that of crime.

As soon as we got rid of the backroom attitude and brought our apparatus fully into the Department with an inexhaustible supply of living patients with fascinating clinical problems, we were able to get ahead really fast. Any new technique becomes more attractive if its clinical usefulness can be demonstrated without harm, indignity or discomfort to the patient... Anyone who is satisfied with his diagnostic ability and with his surgical results is unlikely to contribute much to the launching of a new medical science. He should first be consumed with a divine discontent with things as they are. It greatly helps, of course, to have the right idea at the right time, and quite good ideas may come, Archimedes fashion, in one's bath..

As soon as we touch the complex processes that go on in a living thing, be it plant or animal, we are at once forced to use the methods of this science [chemistry]. No longer will the microscope, the kymograph, the scalpel avail for the complete solution of the problem. For the further analysis of these phenomena which are in flux and flow, the investigator must associate himself with those who have labored in fields where molecules and atoms, rather than multicellular tissues or even unicellular organisms, are the units of study.

As the birth of living creatures are ill shapen; so are all innovations, which are the births of time.

As the births of living creatures are ill-shapen, so are all innovations, which are the births of time.

As was predicted at the beginning of the Human Genome Project, getting the sequence will be the easy part as only technical issues are involved. The hard part will be finding out what it means, because this poses intellectual problems of how to understand the participation of the genes in the functions of living cells.

Asian Homo erectus died without issue and does not enter our immediate ancestry (for we evolved from African populations); Neanderthal people were collateral cousins, perhaps already living in Europe while we emerged in Africa... In other words, we are an improbable and fragile entity, fortunately successful after precarious beginnings as a small population in Africa, not the predictable end result of a global tendency. We are a thing, an item of history, not an embodiment of general principles.

At the beginning of its existence as a science, biology was forced to take cognizance of the seemingly boundless variety of living things, for no exact study of life phenomena was possible until the apparent chaos of the distinct kinds of organisms had been reduced to a rational system. Systematics and morphology, two predominantly descriptive and observational disciplines, took precedence among biological sciences during the eighteenth and nineteenth centuries. More recently physiology has come to the foreground, accompanied by the introduction of quantitative methods and by a shift from the observationalism of the past to a predominance of experimentation.

Basic research at universities comes in two varieties: research that requires big bucks and research that requires small bucks. Big bucks research is much like government research and in fact usually is government research but done for the government under contract. Like other government research, big bucks academic research is done to understand the nature and structure of the universe or to understand life, which really means that it is either for blowing up the world or extending life, whichever comes first. Again, that's the government's motivation. The universities' motivation for conducting big bucks research is to bring money in to support professors and graduate students and to wax the floors of ivy-covered buildings. While we think they are busy teaching and learning, these folks are mainly doing big bucks basic research for a living, all the while priding themselves on their terrific summer vacations and lack of a dress code.
Smalls bucks research is the sort of thing that requires paper and pencil, and maybe a blackboard, and is aimed primarily at increasing knowledge in areas of study that don't usually attract big bucks - that is, areas that don't extend life or end it, or both. History, political science, and romance languages are typically small bucks areas of basic research. The real purpose of small bucks research to the universities is to provide a means of deciding, by the quality of their small bucks research, which professors in these areas should get tenure.

Being also in accord with Goethe that discoveries are made by the age and not by the individual, I should consider the instances to be exceedingly rare of men who can be said to be living before their age, and to be the repository of knowledge quite foreign to the thought of the time. The rule is that a number of persons are employed at a particular piece of work, but one being a few steps in advance of the others is able to crown the edifice with his name, or, having the ability to generalise already known facts, may become in time to be regarded as their originator. Therefore it is that one name is remembered whilst those of coequals have long been buried in obscurity.

Besides agreeing with the aims of vegetarianism for aesthetic and moral reasons, it is my view that a vegetarian manner of living by its purely physical effect on the human temperament would most beneficially influence the lot of mankind.

Better Things for Better Living Through Chemistry.

Biology occupies a position among the sciences both marginal and central. Marginal because, the living world, constituting only a tiny and very “special” part of the universe, it does not seem likely that the study of living beings will ever uncover general laws applicable outside the biosphere. But if the ultimate aim of the whole of science is indeed, as I believe, to clarify man's relationship to the universe, then biology must be accorded a central position, since of all the disciplines it is the one that endeavours to go most directly to the heart of the problems that must be resolved before that of “human nature” can even be framed in other than metaphysical terms.

Biophilia, if it exists, and I believe it exists, is the innately emotional affiliation of human beings to other living organisms.

Borel makes the amusing supposition of a million monkeys allowed to play upon the keys of a million typewriters. What is the chance that this wanton activity should reproduce exactly all of the volumes which are contained in the library of the British Museum? It certainly is not a large chance, but it may be roughly calculated, and proves in fact to be considerably larger than the chance that a mixture of oxygen and nitrogen will separate into the two pure constituents. After we have learned to estimate such minute chances, and after we have overcome our fear of numbers which are very much larger or very much smaller than those ordinarily employed, we might proceed to calculate the chance of still more extraordinary occurrences, and even have the boldness to regard the living cell as a result of random arrangement and rearrangement of its atoms. However, we cannot but feel that this would be carrying extrapolation too far. This feeling is due not merely to a recognition of the enormous complexity of living tissue but to the conviction that the whole trend of life, the whole process of building up more and more diverse and complex structures, which we call evolution, is the very opposite of that which we might expect from the laws of chance.

But many of our imaginations and investigations of nature are futile, especially when we see little living animals and see their legs and must judge the same to be ten thousand times thinner than a hair of my beard, and when I see animals living that are more than a hundred times smaller and am unable to observe any legs at all, I still conclude from their structure and the movements of their bodies that they do have legs... and therefore legs in proportion to their bodies, just as is the case with the larger animals upon which I can see legs... Taking this number to be about a hundred times smaller, we therefore find a million legs, all these together being as thick as a hair from my beard, and these legs, besides having the instruments for movement, must be provided with vessels to carry food.

But psychoanalysis has taught that the dead—a dead parent, for example—can be more alive for us, more powerful, more scary, than the living. It is the question of ghosts.

But, you might say, “none of this shakes my belief that 2 and 2 are 4.” You are quite right, except in marginal cases—and it is only in marginal cases that you are doubtful whether a certain animal is a dog or a certain length is less than a meter. Two must be two of something, and the proposition “2 and 2 are 4” is useless unless it can be applied. Two dogs and two dogs are certainly four dogs, but cases arise in which you are doubtful whether two of them are dogs. “Well, at any rate there are four animals,” you may say. But there are microorganisms concerning which it is doubtful whether they are animals or plants. “Well, then living organisms,” you say. But there are things of which it is doubtful whether they are living organisms or not. You will be driven into saying: “Two entities and two entities are four entities.” When you have told me what you mean by “entity,” we will resume the argument.

By its very nature the uterus is a field for growing the seeds, that is to say the ova, sown upon it. Here the eggs are fostered, and here the parts of the living [fetus], when they have further unfolded, become manifest and are made strong. Yet although it has been cast off by the mother and sown, the egg is weak and powerless and so requires the energy of the semen of the male to initiate growth. Hence in accordance with the laws of Nature, and like the other orders of living things, women produce eggs which, when received into the chamber of the uterus and fecundated by the semen of the male, unfold into a new life.

Capitalism, though it may not always give the scientific worker a living wage, will always protect him, as being one of the geese which produce golden eggs for its table.

Cell genetics led us to investigate cell mechanics. Cell mechanics now compels us to infer the structures underlying it. In seeking the mechanism of heredity and variation we are thus discovering the molecular basis of growth and reproduction. The theory of the cell revealed the unity of living processes; the study of the cell is beginning to reveal their physical foundations.

Cellular pathology is not an end if one cannot see any alteration in the cell. Chemistry brings the clarification of living processes nearer than does anatomy. Each anatomical change must have been preceded by a chemical one.

Certainlie these things agree,
The Priest, the Lawyer, & Death all three:
Death takes both the weak and the strong.
The lawyer takes from both right and wrong,
And the priest from living and dead has his Fee.

Characteristically skeptical of the idea that living things would faithfully follow mathematical formulas, [Robert Harper] seized upon factors in corn which seemed to blend in the hybrid—rather than be represented by plus or minus signs, and put several seasons into throwing doubt upon the concept of immutable hypothetical units of inheritance concocted to account for selected results.

Chemical biodynamics, involving as it does, the fusion of many scientific disciplines, … [played a role] in the elucidation of the carbon cycle. It can be expected to take an increasingly important place in the understanding of the dynamics of living organisms on a molecular level.

Considered from the standpoint of chemistry, living bodies appear to us as laboratories of chemical processes, for they undergo perpetual changes in their material substrate. They draw materials from the outside world and combine them with the mass of their liquid and solid parts.

Culture may even be described simply as that which makes life worth living.

Deprived, therefore, as regards this period, of any assistance from history, but relieved at the same time from the embarrassing interference of tradition, the archaeologist is free to follow the methods which have been so successfully pursued in geology—the rude bone and stone implements of bygone ages being to the one what the remains of extinct animals are to the other. The analogy may be pursued even further than this. Many mammalia which are extinct in Europe have representatives still living in other countries. Our fossil pachyderms, for instance, would be almost unintelligible but for the species which still inhabit some parts of Asia and Africa; the secondary marsupials are illustrated by their existing representatives in Australia and South America; and in the same manner, if we wish clearly to understand the antiquities of Europe, we must compare them with the rude implements and weapons still, or until lately, used by the savage races in other parts of the world. In fact, the Van Diemaner and South American are to the antiquary what the opossum and the sloth are to the geologist.

Despite the high long-term probability of extinction, every organism alive today, including every person reading this paper, is a link in an unbroken chain of parent-offspring relationships that extends back unbroken to the beginning of life on earth. Every living organism is a part of an enormously long success story—each of its direct ancestors has been sufficiently well adapted to its physical and biological environments to allow it to mature and reproduce successfully. Viewed thus, adaptation is not a trivial facet of natural history, but a biological attribute so central as to be inseparable from life itself.

Differences between individuals are the raw materials for evolutionary change and for the evolution of adaptations, yet of course most physiologists treat these differences as noise that is to be filtered out. From the standpoint of physiological ecology, the traditional emphasis of physiologists on central tendencies rather than on variance has some unhappy consequences. Variation is not just noise; it is also the stuff of evolution and a central attribute of living systems. The physiological differences between individuals in the same species or population, and also the patterns of variation in different groups, must not be ignored.

Disease is not something personal and special, but only a manifestation of life under modified conditions, operating according to the same laws as apply to the living body at all times, from the first moment until death.

Disease may be defined as “A change produced in living things in consequence of which they are no longer in harmony with their environment.”

Doctor, no medicine.—We are machines made to live—organized expressly for that purpose.—Such is our nature.—Do not counteract the living principle.—Leave it at liberty to defend itself, and it will do better than your drugs.

Does it seem all but incredible to you that intelligence should travel for two thousand miles, along those slender copper lines, far down in the all but fathomless Atlantic; never before penetrated … save when some foundering vessel has plunged with her hapless company to the eternal silence and darkness of the abyss? Does it seem … but a miracle … that the thoughts of living men … should burn over the cold, green bones of men and women, whose hearts, once as warm as ours, burst as the eternal gulfs closed and roared over them centuries ago?

Domesticated biotechnology, once it gets into the hands of housewives and children, will give us an explosion of diversity of new living creatures … New lineages will proliferate to replace those that monoculture farming and deforestation have destroyed. Designing genomes will be a personal thing, a new art form as creative as painting or sculpture. Few of the new creations will be masterpieces, but a great many will bring joy to their creators and variety to our fauna and flora.

Each time one of the medicine men dies, it's as if a library has burned down.
{Referring to potential knowledge from indiginous peoples of the medicinal value of tropical plants, speaking as director of the plant program of the World Wildlife Fund and having spent many months living with the Tirio tribe on the Suriname-Brazil border.]

Engineering is a living branch of human activity and its frontiers are by no means exhausted.

Ere long intelligence—transmitted without wires—will throb through the earth like a pulse through a living organism. The wonder is that, with the present state of knowledge and the experiences gained, no attempt is being made to disturb the electrostatic or magnetic condition of the earth, and transmit, if nothing else, intelligence.

Eskimos living in a world of ice have no word at all for that substance—and this has been cited as evidence of their primitive mentality. But ice as such is of no interest to an Eskimo; what is of interest, indeed of vital importance, are the different kinds of ice with which he must deal virtually every day of his life.

Euclidean mathematics assumes the completeness and invariability of mathematical forms; these forms it describes with appropriate accuracy and enumerates their inherent and related properties with perfect clearness, order, and completeness, that is, Euclidean mathematics operates on forms after the manner that anatomy operates on the dead body and its members. On the other hand, the mathematics of variable magnitudes—function theory or analysis—considers mathematical forms in their genesis. By writing the equation of the parabola, we express its law of generation, the law according to which the variable point moves. The path, produced before the eyes of the student by a point moving in accordance to this law, is the parabola.
If, then, Euclidean mathematics treats space and number forms after the manner in which anatomy treats the dead body, modern mathematics deals, as it were, with the living body, with growing and changing forms, and thus furnishes an insight, not only into nature as she is and appears, but also into nature as she generates and creates,—reveals her transition steps and in so doing creates a mind for and understanding of the laws of becoming. Thus modern mathematics bears the same relation to Euclidean mathematics that physiology or biology … bears to anatomy.

Even the facts of science may dust the mind by their dryness, unless they are … rendered fertile by the dews of fresh and living truth. Knowledge does not come to us by details, but in flashes of light from heaven.

Every chemical substance, whether natural or artificial, falls into one of two major categories, according to the spatial characteristic of its form. The distinction is between those substances that have a plane of symmetry and those that do not. The former belong to the mineral, the latter to the living world.

Every living being is also a fossil. Within it, all the way down to the microscopic structure of its proteins, it bears the traces if not the stigmata of its ancestry.

Every living language, like the perspiring bodies of living creatures, is in perpetual motion and alteration; some words go off, and become obsolete; others are taken in, and by degrees grow into common use; or the same word is inverted to a new sense and notion, which in tract of time makes as observable a change in the air and features of a language as age makes in the lines and mien of a face.

Every living thing from a living thing.
Omne vivum ex vivo.

Every living thing is a sort of imperialist, seeking to transform as much as possible of its environment into itself and its seed. When we compare the (present) human population of the globe with… that of former times, we see that “chemical imperialism” has been… the main end to which human intelligence has been devoted.

Every living thing is made of cells, and everything a living thing does is done by the cells that make it up.

Every subject in Davy’s mind has the principle of Vitality. Living thoughts spring up like Turf under his feet.

Everyone is aware of the difficult and menacing situation in which human society–shrunk into one community with a common fate–now finds itself, but only a few act accordingly. Most people go on living their every-day life: half frightened, half indifferent, they behold the ghostly tragicomedy which is being performed on the international stage before the eyes and ears of the world. But on that stage, on which the actors under the floodlights play their ordained parts, our fate of tomorrow, life or death of the nations, is being decided.

Everything is made of atoms ... Everything that animals do, atoms do. ... There is nothing that living things do that cannot be understood from the point of view that they are made of atoms acting according to the laws of physics.

Evolution is the conviction that organisms developed their current forms by an extended history of continual transformation, and that ties of genealogy bind all living things into one nexus. Panselectionism is a denial of history, for perfection covers the tracks of time. A perfect wing may have evolved to its current state, but it may have been created just as we find it. We simply cannot tell if perfection be our only evidence. As Darwin himself understood so well, the primary proofs of evolution are oddities and imperfections that must record pathways of historical descent–the panda’s thumb and the flamingo’s smile of my book titles (chosen to illustrate this paramount principle of history).