[Dubious attribution] We are all continually faced with great opportunities which are brilliantly disguised as unsolvable problems.

[For equal opportunity and recognition, women in science] must be prepared to work hard for the work’s sake, without thought of what it may bring to them in the way of personal acclaim and emolument. While scientific research is exciting it has its dull and plodding moments. One may delve and delve and analyze and analyze for months, and even years, without seeing anything. Then suddenly, through accumulative observation, the idea comes!”

[Richard Drew] always encouraged his people to pursue ideas… He said, “If it’s a dumb idea, you’ll find out. You’ll smack into that brick wall, then you’ll stagger back and see another opportunity that you wouldn’t have seen otherwise.”

[T]here are some common animal behaviors that seem to favor the development of intelligence, behaviors that might lead to brainy beasts on many worlds. Social interaction is one of them. If you're an animal that hangs out with others, then there's clearly an advantage in being smart enough to work out the intentions of the guy sitting next to you (before he takes your mate or your meal). And if you're clever enough to outwit the other members of your social circle, you'll probably have enhanced opportunity to breed..., thus passing on your superior intelligence. ... Nature—whether on our planet or some alien world—will stumble into increased IQ sooner or later.

A clash of doctrines is not a disaster—it is an opportunity.

A teacher of mathematics has a great opportunity. If he fills his allotted time with drilling his students in routine operations he kills their interest, hampers their intellectual development, and misuses his opportunity. But if he challenges the curiosity of his students by setting them problems proportionate to their knowledge, and helps them to solve their problems with stimulating questions, he may give them a taste for, and some means of, independent thinking.

Adventure isn’t hanging on a rope off the side of a mountain. Adventure is an attitude that we must apply to the day to day obstacles of life - facing new challenges, seizing new opportunities, testing our resources against the unknown and in the process, discovering our own unique potential.

All that is valuable in human society depends upon the opportunity for development accorded the individual.

And yet, it will be no cool process of mere science … with which we face this new age of right and opportunity….

As every circumstance relating to so capital a discovery as this (the greatest, perhaps, that has been made in the whole compass of philosophy, since the time of Sir Isaac Newton) cannot but give pleasure to all my readers, I shall endeavour to gratify them with the communication of a few particulars which I have from the best authority. The Doctor [Benjamin Franklin], after having published his method of verifying his hypothesis concerning the sameness of electricity with the matter lightning, was waiting for the erection of a spire in Philadelphia to carry his views into execution; not imagining that a pointed rod, of a moderate height, could answer the purpose; when it occurred to him, that, by means of a common kite, he could have a readier and better access to the regions of thunder than by any spire whatever. Preparing, therefore, a large silk handkerchief, and two cross sticks, of a proper length, on which to extend it, he took the opportunity of the first approaching thunder storm to take a walk into a field, in which there was a shed convenient for his purpose. But dreading the ridicule which too commonly attends unsuccessful attempts in science, he communicated his intended experiment to no body but his son, who assisted him in raising the kite.
The kite being raised, a considerable time elapsed before there was any appearance of its being electrified. One very promising cloud passed over it without any effect; when, at length, just as he was beginning to despair of his contrivance, he observed some loose threads of the hempen string to stand erect, and to avoid one another, just as if they had been suspended on a common conductor. Struck with this promising appearance, he inmmediately presented his knuckle to the key, and (let the reader judge of the exquisite pleasure he must have felt at that moment) the discovery was complete. He perceived a very evident electric spark. Others succeeded, even before the string was wet, so as to put the matter past all dispute, and when the rain had wetted the string, he collected electric fire very copiously. This happened in June 1752, a month after the electricians in France had verified the same theory, but before he had heard of any thing that they had done.

As the saying goes, the Stone Age did not end because we ran out of stones; we transitioned to better solutions. The same opportunity lies before us with energy efficiency and clean energy.

As we look ahead through the vista of science with its tremendous possibilities for progress in peacetime, let us not feel that we are looking beyond the horizon of hope. The outlook is not discouraging, for there is no limit to man’s ingenuity and no end to the opportunities for progress.

Casting off the dark fog of verbal philosophy and vulgar medicine, which inculcate names alone ... I tried a series of experiments to explain more clearly many phenomena, particularly those of physiology. In order that I might subject as far as possible the reasonings of the Galenists and Peripatetics to sensory criteria, I began, after trying experiments, to write dialogues in which a Galenist adduced the better-known and stronger reasons and arguments; these a mechanist surgeon refuted by citing to the contrary the experiments I had tried, and a third, neutral interlocutor weighed the reasons advanced by both and provided an opportunity for further progress.

Democracy: everyone should have an equal opportunity to obstruct everybody else.

Developmental Biology, in capitals, is the wave of the future. The creeping reductionism of biochemistry and molecular biology has taken over the cell and heredity, and looks covetously toward the heights of development and evolution. Recent literature is last year. Ancient literature is a decade ago. The rest is history, doubtfully alive. There is no time and often no opportunity to find and study the work of experimental biologists of 50 or 100 years ago, yet that was a time when the world was fresh.
Developmental biology was a lowercase phrase that graduated about 1950 and had previously lived under the cloak of Experimental Zoology

Economists use the expression “opportunity costs” for losses incurred through certain choices made over others, including ignorance and inaction. For systematics, or more precisely the neglect of systematics and the biological research dependent upon it, the costs are very high.

Fertilization of mammalian eggs is followed by successive cell divisions and progressive differentiation, first into the early embryo and subsequently into all of the cell types that make up the adult animal. Transfer of a single nucleus at a specific stage of development, to an enucleated unfertilized egg, provided an opportunity to investigate whether cellular differentiation to that stage involved irreversible genetic modification. The first offspring to develop from a differentiated cell were born after nuclear transfer from an embryo-derived cell line that had been induced to became quiescent. Using the same procedure, we now report the birth of live lambs from three new cell populations established from adult mammary gland, fetus and embryo. The fact that a lamb was derived from an adult cell confirms that differentiation of that cell did not involve the irreversible modification of genetic material required far development to term. The birth of lambs from differentiated fetal and adult cells also reinforces previous speculation that by inducing donor cells to became quiescent it will be possible to obtain normal development from a wide variety of differentiated cells.
[Co-author of paper announcing the cloned sheep, ‘Dolly’.]

First, it must be a pleasure to study the human body the most miraculous masterpiece of nature and to learn about the smallest vessel and the smallest fiber. But second and most important, the medical profession gives the opportunity to alleviate the troubles of the body, to ease the pain, to console a person who is in distress, and to lighten the hour of death of many a sufferer.

For the environmentalists, The Space Option is the ultimate environmental solution. For the Cornucopians, it is the technological fix that they are relying on. For the hard core space community, the obvious by-product would be the eventual exploration and settlement of the solar system. For most of humanity however, the ultimate benefit is having a realistic hope in a future with possibilities.... If our species does not soon embrace this unique opportunity with sufficient commitment, it may miss its one and only chance to do so. Humanity could soon be overwhelmed by one or more of the many challenges it now faces. The window of opportunity is closing as fast as the population is increasing. Our future will be either a Space Age or a Stone Age.

For those who have devoted their lives to better understanding the peopling of the New World, the Kennewick find is a rare opportunity for a significant increase in knowledge about who the early Americans were and how they relate to living tribes.

He should avail himself of their resources in such ways as to advance the expression of the spirit in the life of mankind. He should use them so as to afford to every human being the greatest possible opportunity for developing and expressing his distinctively human capacity as an instrument of the spirit, as a centre of sensitive and intelligent awareness of the objective universe, as a centre of love of all lovely things, and of creative action for the spirit.

Hospitals are only an intermediate stage of civilization, never intended ... to take in the whole sick population. May we hope that the day will come ... when every poor sick person will have the opportunity of a share in a district sick-nurse at home.

Human societies increased the abundance and distribution of useful species. This can also be used to preserve the forest, I think. We can use this as an opportunity to reduce the impacts of deforestation. Now we have huge plantations of soybeans that are destroying the Amazon—while in the forest we have lots of plants that can be used while maintaining the forest as it is.

I believe television is going to be the test of the modern world, and that in this new opportunity to see beyond the range of our vision we shall discover either a new and unbearable disturbance of the general peace or a saving radiance in the sky. We shall stand or fall by television—of that I am quite sure

I believed that, instead of the multiplicity of rules that comprise logic, I would have enough in the following four, as long as I made a firm and steadfast resolution never to fail to observe them.
The first was never to accept anything as true if I did not know clearly that it was so; that is, carefully to avoid prejudice and jumping to conclusions, and to include nothing in my judgments apart from whatever appeared so clearly and distinctly to my mind that I had no opportunity to cast doubt upon it.
The second was to subdivide each on the problems I was about to examine: into as many parts as would be possible and necessary to resolve them better.
The third was to guide my thoughts in an orderly way by beginning, as if by steps, to knowledge of the most complex, and even by assuming an order of the most complex, and even by assuming an order among objects in! cases where there is no natural order among them.
And the final rule was: in all cases, to make such comprehensive enumerations and such general review that I was certain not to omit anything.
The long chains of inferences, all of them simple and easy, that geometers normally use to construct their most difficult demonstrations had given me an opportunity to think that all the things that can fall within the scope of human knowledge follow from each other in a similar way, and as long as one avoids accepting something as true which is not so, and as long as one always observes the order required to deduce them from each other, there cannot be anything so remote that it cannot be reached nor anything so hidden that it cannot be uncovered.

I cannot find anything showing early aptitude for acquiring languages; but that he [Clifford] had it and was fond of exercising it in later life is certain. One practical reason for it was the desire of being able to read mathematical papers in foreign journals; but this would not account for his taking up Spanish, of which he acquired a competent knowledge in the course of a tour to the Pyrenees. When he was at Algiers in 1876 he began Arabic, and made progress enough to follow in a general way a course of lessons given in that language. He read modern Greek fluently, and at one time he was furious about Sanskrit. He even spent some time on hieroglyphics. A new language is a riddle before it is conquered, a power in the hand afterwards: to Clifford every riddle was a challenge, and every chance of new power a divine opportunity to be seized. Hence he was likewise interested in the various modes of conveying and expressing language invented for special purposes, such as the Morse alphabet and shorthand. … I have forgotten to mention his command of French and German, the former of which he knew very well, and the latter quite sufficiently; …

I cannot join the space program and restart my life as an astronaut, but this opportunity to connect my abilities as an educator with my interests in history and space is a unique opportunity to fulfill my early fantasies. I watched the space program being born and would like to participate.

I have said that the investigation for which the teeth of the shark had furnished an opportunity, was very near an end... But thereafter, while I was examining more carefully these details of both places and bodies [sedimentary deposits and shells], these day by day presented points of doubt to me as they followed one another in indissoluble connection, so that I saw myself again and again brought back to the starting-place, as it were, when I thought I was nearest the goal. I might compare those doubts to the heads of the Lernean Hydra, since when one of them had been got rid of, numberless others were born; at any rate, I saw that I was wandering about in a sort of labyrinth, where the nearer one approaches the exit, the wider circuits does one tread.

I like to tell students that the jobs I took [at NASA] after my Ph.D. were not in existence only a few years before. New opportunities can open up for you in this ever changing field.

I shall esteem it a very great honor to have a degree from the institution that gave Elizabeth Blackwell her opportunity to study medicine.

I shall explain a System of the World differing in many particulars from any yet known, answering in all things to the common Rules of Mechanical Motions: This depends upon three Suppositions. First, That all Cœlestial Bodies whatsoever, have an attraction or gravitating power towards their own Centers, whereby they attract not only their own parts, and keep them from flying from them, as we may observe the Earth to do, but that they do also attract all the other Cœlestial bodies that are within the sphere of their activity; and consequently that not only the Sun and Moon have an influence upon the body and motion the Earth, and the Earth upon them, but that Mercury also Venus, Mars, Saturn and Jupiter by their attractive powers, have a considerable influence upon its motion in the same manner the corresponding attractive power of the Earth hath a considerable influence upon every one of their motions also. The second supposition is this, That all bodies whatsoever that are put into a direct and simple motion, will continue to move forward in a streight line, till they are by some other effectual powers deflected and bent into a Motion, describing a Circle, Ellipse, or some other more compounded Curve Line. The third supposition is, That these attractive powers are so much the more powerful in operating, by how much the nearer the body wrought upon is to their own Centers. Now what these several degrees are I have not yet experimentally verified; but it is a notion, which if fully prosecuted as it ought to be, will mightily assist the Astronomer to reduce all the Cœlestial Motions to a certain rule, which I doubt will never be done true without it. He that understands the nature of the Circular Pendulum and Circular Motion, will easily understand the whole ground of this Principle, and will know where to find direction in Nature for the true stating thereof. This I only hint at present to such as have ability and opportunity of prosecuting this Inquiry, and are not wanting of Industry for observing and calculating, wishing heartily such may be found, having myself many other things in hand which I would first compleat and therefore cannot so well attend it. But this I durst promise the Undertaker, that he will find all the Great Motions of the World to be influenced by this Principle, and that the true understanding thereof will be the true perfection of Astronomy.

I therefore took this opportunity and also began to consider the possibility that the Earth moved. Although it seemed an absurd opinion, nevertheless, because I knew that others before me had been granted the liberty of imagining whatever circles they wished to represent the phenomena of the stars, I thought that I likewise would readily be allowed to test whether, by assuming some motion of the Earth's, more dependable representations than theirs could be found for the revolutions of the heavenly spheres.

I think every child born on this planet up to the age of about four or five is fascinated by the natural world. If they aren’t it’s because we deprive them of the opportunity. Over half the world’s population is urbanised and the thought that some children may grow up not looking at a pond or knowing how plants grow is a terrible thing. If you lose that delight and joy and intoxication, you’ve lost something hugely precious.

I took this view of the subject. The medulla spinalis has a central division, and also a distinction into anterior and posterior fasciculi, corresponding with the anterior and posterior portions of the brain. Further we can trace down the crura of the cerebrum into the anterior fasciculus of the spinal marrow, and the crura of the cerebellum into the posterior fasciculus. I thought that here I might have an opportunity of touching the cerebellum, as it were, through the posterior portion of the spinal marrow, and the cerebrum by the anterior portion. To this end I made experiments which, though they were not conclusive, encouraged me in the view I had taken. I found that injury done to the anterior portion of the spinal marrow, convulsed the animal more certainly than injury done to the posterior portion; but I found it difficult to make the experiment without injuring both portions.

I was unable to devote myself to the learning of this al-jabr [algebra] and the continued concentration upon it, because of obstacles in the vagaries of Time which hindered me; for we have been deprived of all the people of knowledge save for a group, small in number, with many troubles, whose concern in life is to snatch the opportunity, when Time is asleep, to devote themselves meanwhile to the investigation and perfection of a science; for the majority of people who imitate philosophers confuse the true with the false, and they do nothing but deceive and pretend knowledge, and they do not use what they know of the sciences except for base and material purposes; and if they see a certain person seeking for the right and preferring the truth, doing his best to refute the false and untrue and leaving aside hypocrisy and deceit, they make a fool of him and mock him.

I wouldn’t miss this opportunity for anything. For the chance to work on these conservation issues, to serve my country, to work for this president, I’d do it all over again, every single minute.

If a man is in any sense a real mathematician, then it is a hundred to one that his mathematics will be far better than anything else he can do, and that it would be silly if he surrendered any decent opportunity of exercising his one talent in order to do undistinguished work in other fields. Such a sacrifice could be justified only by economic necessity of age.

If the man of science chose to follow the example of historians and pulpit-orators, and to obscure strange and peculiar phenomena by employing a hollow pomp of big and sounding words, this would be his opportunity; for we have approached one of the greatest mysteries which surround the problem of animated nature and distinguish it above all other problems of science. To discover the relations of man and woman to the egg-cell would be almost equivalent of the egg-cell in the body of the mother, the transfer to it by means of the seed, of the physical and mental characteristics of the father, affect all the questions which the human mind has ever raised in regard to existence.

If we use resources productively and take to heart the lessons learned from coping with the energy crisis, we face a future confronted only, as Pogo, once said, by insurmountable opportunities. The many crises facing us should be seen, then, not as threats, but as chances to remake the future so it serves all beings.

In Melvin Calvin’s office there were four photographs: Michael Polanyi, Joel Hildebrand, Gilbert N. Lewis, and Ernest O. Lawrence. These scientists were his mentors: Polanyi for introducing him to the chemistry of phthalocyanine; Hildebrand for bringing him to Berkeley; Lewis, perhaps his most influential teacher; and Lawrence, who provided him the opportunity to work with the new scientific tool of radioactive carbon, which enabled the search for the path of carbon in photosynthesis to be successful.

In these strenuous times, we are likely to become morbid and look constantly on the dark side of life, and spend entirely too much time considering and brooding over what we can't do, rather than what we can do, and instead of growing morose and despondent over opportunities either real or imaginary that are shut from us, let us rejoice at the many unexplored fields in which there is unlimited fame and fortune to the successful explorer and upon which there is no color line; simply the survival of the fittest.

Instead of being presented with stereotypes by age, sex, color, class, or religion, children must have the opportunity to learn that within each range, some people are loathsome and some are delightful.

It may metaphorically be said that natural selection is daily and hourly scrutinising, throughout the world, the slightest variations; rejecting those that are bad, preserving and adding up all that are good; silently and insensibly working, whenever and wherever opportunity offers, at the improvement of each organic being in relation to its organic and inorganic conditions of life. We see nothing of these slow changes in progress, until the hand of time has marked the lapse of ages...

Life is short, the Art long, opportunity fleeting, experience treacherous, judgment difficult. The physician must be ready, not only to do his duty himself, but also to secure the co-operation of the patient, of the attendants and of externals.

Many who have never had an opportunity of knowing any more about mathematics confound it with arithmetic, and consider it an arid science. In reality, however, it is a science which requires a great amount of imagination.

Much of the work we do as scientists involves filling in the details about matters that are basically understood already, or applying standard techniques to new specific cases. But occasionally there is a question that offers an opportunity for a really major discovery.

Never confuse a fool’s gold opportunity with a silver bullet solution.

Never regard study as a duty, but as the enviable opportunity to learn to know the liberating influence of beauty in the realm of the spirit for your own personal joy and to the profit of the community to which your later work belongs.

No great man ever complains of want of opportunity.

Now it is a well-known principle of zoological evolution that an isolated region, if large and sufficiently varied in its topography, soil, climate and vegetation, will give rise to a diversified fauna according to the law of adaptive radiation from primitive and central types. Branches will spring off in all directions to take advantage of every possible opportunity of securing food. The modifications which animals undergo in this adaptive radiation are largely of mechanical nature, they are limited in number and kind by hereditary, stirp or germinal influences, and thus result in the independent evolution of similar types in widely-separated regions under the law of parallelism or homoplasy. This law causes the independent origin not only of similar genera but of similar families and even of our similar orders. Nature thus repeats herself upon a vast scale, but the similarity is never complete and exact.

Occurrences that other men would have noted only with the most casual interest became for Whitney exciting opportunities to experiment. Once he became disturbed by a scientist's seemingly endless pursuit of irrelevant details in the course of an experiment, and criticized this as being as pointless as grabbing beans out of a pot, recording the numbers, and then analyzing the results. Later that day, after he had gone home, his simile began to intrigue him, and he asked himself whether it would really be pointless to count beans gathered in such a random manner. Another man might well have dismissed this as an idle fancy, but to Whitney an opportunity to conduct an experiment was not to be overlooked. Accordingly, he set a pot of beans beside his bed, and for several days each night before retiring he would take as many beans as he could grasp in one hand and make a note of how many were in the handful. After several days had passed he was intrigued to find that the results were not as unrewarding as he had expected. He found that each handful contained more beans than the one before, indicating that with practice he was learning to grasp more and more beans. “This might be called research in morphology, the science of animal structure,” he mused. “My hand was becoming webbed … so I said to myself: never label a real experiment useless, it may reveal something unthought of but worth knowing.”

One of the first and foremost duties of the teacher is not to give his students the impression that mathematical problems have little connection with each other, and no connection at all with anything else. We have a natural opportunity to investigate the connections of a problem when looking back at its solution.

Opportunity is missed by most people because it is dressed in overalls and looks like work.

Rampant scientific illiteracy in the general public is, in my opinion, one major cause of the current lack of opportunities for scientists. … A public that is ignorant of science, and of how science is done, is not going to support scientific research enthusiastically.

Scientists tend to resist interdisciplinary inquiries into their own territory. In many instances, such parochialism is founded on the fear that intrusion from other disciplines would compete unfairly for limited financial resources and thus diminish their own opportunity for research.
[Naming territorial dominance, greed, and fear of the unknown, as some of the influences on the increasing specialization of science]

Signs and symptoms indicate the present, past and future states of the three states of the body (health, illness, neutrality). According to Galen, knowledge of the present state is of advantage only to the patient as it helps him to follow the proper course of management. Knowledge of the past state is useful only to the physician inasmuch as its disclosure by him to the patient brings him a greater respect for his professional advice. Knowledge of the future state is useful to both. It gives an opportunity to the patient to be forewarned to adopt necessary preventative measures and it enhances the reputation of the physician by correctly forecasting the future developments.

The attitude of the intellectual community toward America is shaped not by the creative few but by the many who for one reason or another cannot transmute their dissatisfaction into a creative impulse, and cannot acquire a sense of uniqueness and of growth by developing and expressing their capacities and talents. There is nothing in contemporary America that can cure or alleviate their chronic frustration. They want power, lordship, and opportunities for imposing action. Even if we should banish poverty from the land, lift up the Negro to true equality, withdraw from Vietnam, and give half of the national income as foreign aid, they will still see America as an air-conditioned nightmare unfit for them to live in.

The dispute between evolutionists and creation scientists offers textbook writers and teachers a wonderful opportunity to provide students with insights into the philosophy and methods of science. … What students really need to know is … how scientists judge the merit of a theory. Suppose students were taught the criteria of scientific theory evaluation and then were asked to apply these criteria … to the two theories in question. Wouldn’t such a task qualify as authentic science education? … I suspect that when these two theories are put side by side, and students are given the freedom to judge their merit as science, creation theory will fail ignominiously (although natural selection is far from faultless). … It is not only bad science to allow disputes over theory to go unexamined, but also bad education.

The important thing is not so much that every child should be taught, as that every child should have the opportunity of teaching itself. What does it matter if the pupil know a little more or a little less? A boy who leaves school knowing much, but hating his lessons, will soon have forgotten all he ever learned; while another who had acquired a thirst for knowledge, even if he had learned little, would soon teach himself more than the first ever knew.

The investigation of causal relations between economic phenomena presents many problems of peculiar difficulty, and offers many opportunities for fallacious conclusions. Since the statistician can seldom or never make experiments for himself, he has to accept the data of daily experience, and discuss as best he can the relations of a whole group of changes; he cannot, like the physicist, narrow down the issue to the effect of one variation at a time. The problems of statistics are in this sense far more complex than the problems of physics.

The justification for [basic research] is that this constitutes the fount of all new knowledge, without which the opportunities for further technical progress must eventually become exhausted.

The kind of lecture which I have been so kindly invited to give, and which now appears in book form, gives one a rare opportunity to allow the bees in one's bonnet to buzz even more noisily than usual.

The maintenance of biological diversity requires special measures that extend far beyond the establishment of nature reserves. Several reasons for this stand out. Existing reserves have been selected according to a number of criteria, including the desire to protect nature, scenery, and watersheds, and to promote cultural values and recreational opportunities. The actual requirements of individual species, populations, and communities have seldom been known, nor has the available information always been employed in site selection and planning for nature reserves. The use of lands surrounding nature reserves has typically been inimical to conservation, since it has usually involved heavy use of pesticides, industrial development, and the presence of human settlements in which fire, hunting, and firewood gathering feature as elements of the local economy.

The meaning of geography is as much a sealed book to the person of ordinary intelligence and education as the meaning of a great cathedral would be to a backwoodsman, and yet no cathedral can be more suggestive of past history in its many architectural forms than is the land about us, with its innumerable and marvellously significant geographic forms. It makes one grieve to think of opportunity for mental enjoyment that is last because of the failure of education in this respect.

The Nobel Prize gives you an opportunity to make a fool of yourself in public.

The opportunities of man are limited only by his imagination. But so few have imagination that there are ten thousand fiddlers to one composer.

The reason so many people never get anywhere in life is because when opportunity knocks, they are out in the backyard looking for four-leaf clovers.

The regularity with which we conclude that further advances in a particular field are impossible seems equaled only by the regularity with which events prove that we are of too limited vision. And it always seems to be those who have the fullest opportunity to know who are the most limited in view. What, then, is the trouble? I think that one answer should be: we do not realize sufficiently that the unknown is absolutely infinite, and that new knowledge is always being produced.

The responsibility which rests upon man is proportional to the ability which he possesses and the opportunity which he faces. Perhaps that responsibility is no greater for him than was that of Notharctus or Eohippus or a trilobite, each in his own day, but because of man’s unique abilities it is the greatest responsibility that has ever rested upon any of the earth’s offspring.

The result is that a generation of physicists is growing up who have never exercised any particular degree of individual initiative, who have had no opportunity to experience its satisfactions or its possibilities, and who regard cooperative work in large teams as the normal thing. It is a natural corollary for them to feel that the objectives of these large teams must be something of large social significance.

The right that must become paramount is not the right to procreate, but rather the right of every child to be born with a sound physical and mental constitution, based on a sound genotype. No parents will in that future time have the right to burden society with a malformed or mentally incompetent child. Just as every child must have the right to full educational opportunity and a sound nutrition, so every child has the inalienable right to a sound heritage.

The student should not lose any opportunity of exercising himself in numerical calculation and particularly in the use of logarithmic tables. His power of applying mathematics to questions of practical utility is in direct proportion to the facility which he possesses in computation.

The surgeon is a man of action. By temperament and by training he prefers to serve the sick by operating on them, and he inwardly commiserates with a patient so unfortunate as to have a disease not suited to surgical treatment. Young surgeons, busy mastering the technicalities of the art, are particularly alert to seize every legitimate opportunity to practice technical maneuvers, the more complicated the better.

There exist limitless opportunities in every industry. Where there is an open mind, there will always be a frontier.

There is an insistent tendency among serious social scientists to think of any institution which features rhymed and singing commercials, intense and lachrymose voices urging highly improbable enjoyment, caricatures of the human esophagus in normal and impaired operation, and which hints implausibly at opportunities for antiseptic seduction as inherently trivial. This is a great mistake. The industrial system is profoundly dependent on commercial television and could not exist in its present form without it.

There is waste going on in the business life of our people in many ways—waste both of resources and of opportunities. There is waste of energy due to insufficient occupation, because agriculture gives full employment for only six or seven months in the year. There is waste due to illiteracy, because ninety-four persons out of every hundred are uneducated. There is waste through ignorance of the ways of the civilized people, because we fail to utilize their accumulated asset of wisdom and experience. Waste is also going on through our imperfect acquaintance with the commonplaces of civilization and lack of correct business ideals and business standards in daily life. Mental energy is wasted in caste disputes and village factions. Capital is wasted because money is hoarded instead of being made available for productive purposes. There is waste of health because, although leading moral lives normally, men and women grow prematurely old for want of pride of person and attention to the elementary laws of health. The largest waste of all is the lack of capacity for cooperation, the difficulty of ensuring harmony, sympathy and oneness of feeling, in matters affecting the larger interests of the State.

Thinking is merely the comparing of ideas, discerning relations of likeness and of difference between ideas, and drawing inferences. It is seizing general truths on the basis of clearly apprehended particulars. It is but generalizing and particularizing. Who will deny that a child can deal profitably with sequences of ideas like: How many marbles are 2 marbles and 3 marbles? 2 pencils and 3 pencils? 2 balls and 3 balls? 2 children and 3 children? 2 inches and 3 inches? 2 feet and 3 feet? 2 and 3? Who has not seen the countenance of some little learner light up at the end of such a series of questions with the exclamation, “Why it’s always that way. Isn’t it?” This is the glow of pleasure that the generalizing step always affords him who takes the step himself. This is the genuine life-giving joy which comes from feeling that one can successfully take this step. The reality of such a discovery is as great, and the lasting effect upon the mind of him that makes it is as sure as was that by which the great Newton hit upon the generalization of the law of gravitation. It is through these thrills of discovery that love to learn and intellectual pleasure are begotten and fostered. Good arithmetic teaching abounds in such opportunities.

This is my religion: I am filled with Wonder at the outcome of 4 billion years of evolution here on our speck in the universe and Hope regarding our opportunity to improve the lives of those around us through basic science discoveries and their translation to clinical practice.

Those of us who were familiar with the state of inorganic chemistry in universities twenty to thirty years ago will recall that at that time it was widely regarded as a dull and uninteresting part of the undergraduate course. Usually, it was taught almost entirely in the early years of the course and then chiefly as a collection of largely unconnected facts. On the whole, students concluded that, apart from some relationships dependent upon the Periodic table, there was no system in inorganic chemistry comparable with that to be found in organic chemistry, and none of the rigour and logic which characterised physical chemistry. It was widely believed that the opportunities for research in inorganic chemistry were few, and that in any case the problems were dull and uninspiring; as a result, relatively few people specialized in the subject... So long as inorganic chemistry is regarded as, in years gone by, as consisting simply of the preparations and analysis of elements and compounds, its lack of appeal is only to be expected. The stage is now past and for the purpose of our discussion we shall define inorganic chemistry today as the integrated study of the formation, composition, structure and reactions of the chemical elements and compounds, excepting most of those of carbon.

Thus died Negro Tom [Thomas Fuller], this untaught arithmetician, this untutored scholar. Had his opportunities of improvement been equal to those of thousands of his fellow-men, neither the Royal Society of London, the Academy of Science at Paris, nor even a Newton himself need have been ashamed to acknowledge him a brother in science.
[Thomas Fuller (1710-1790), although enslaved from Africa at age 14, was an arithmetical prodigy. He was known as the Virginia Calculator because of his exceptional ability with arithmetic calculations. His intellectual accomplishments were related by Dr. Benjamin Rush in a letter read to the Pennsylvania Society for the Abolition of Slavery.]

We are placed here with certain talents and capabilities. It is up to each of us to use those talents and capabilities as best you can. If you do that, I think there is a power greater than any of us that will place the opportunities in our way, and if we use our talents properly, we will be living the kind of life we should live.

We cannot expect in the immediate future that all women who seek it will achieve full equality of opportunity. But if women are to start moving towards that goal, we must believe in ourselves or no one else will believe in us; we must match our aspirations with the competence, courage and determination to succeed.

We create our future, by well improving present opportunities: however few and small they be.

We do not inhabit a perfected world where natural selection ruthlessly scrutinizes all organic structures and then molds them for optimal utility. Organisms inherit a body form and a style of embryonic development; these impose constraint s upon future change and adaptation. In many cases, evolutionary pathways reflect inherited patterns more than current environmental demands. These inheritances constrain, but they also provide opportunity. A potentially minor genetic change ... entails a host of complex, nonadaptive consequences ... What ‘play’ would evolution have if each structure were built for a restricted purpose and could be used for nothing else? How could humans learn to write if our brain had not evolved for hunting, social cohesion, or whatever, and could not transcend the adaptive boundaries of its original purpose?

We have an extraordinary opportunity that has arisen only twice before in the history of Western civilization—the opportunity to see everything afresh through a new cosmological lens. We are the first humans privileged to see a face of the universe no earlier culture ever imagined.

We have the opportunity of observing her [Nature] through these delicate and pellucid teguments of the bodies of Insects acting according to her usual course and way, undisturbed, whereas when we endeavour to pry into her secrets by breaking open the doors upon her, and dissecting and mangling creatures whil'st there is life yet within them, we find her indeed at work, but put into such disorder by the violence offer'd, as it may easily be imagin'd how differing a thing we should find, if we could, as we can with a Microscope, in these smaller creatures, quietly peep in at the windows, without frighting her out of her usual byas.

We must somehow keep the dreams of space exploration alive, for in the long run they will prove to be of far more importance to the human race than the attainment of material benefits. Like Darwin, we have set sail upon an ocean: the cosmic sea of the Universe. There can be no turning back. To do so could well prove to be a guarantee of extinction. When a nation, or a race or a planet turns its back on the future, to concentrate on the present, it cannot see what lies ahead. It can neither plan nor prepare for the future, and thus discards the vital opportunity for determining its evolutionary heritage and perhaps its survival.

We no longer can talk of unearned “rights.” We’ll have to get back to working for “rights” to adequate food, housing, education, opportunity, a place in the sun—and not everybody is going to make the grade. I don’t see this obsession with the lowest strata of humanity, against all natural biologic experience. We must accept that life is unfair.

What helps luck is a habit of watching for opportunities, of having a patient but restless mind, of sacrificing one’s ease or vanity, or uniting a love of detail to foresight, and of passing through hard times bravely [and cheerfully].

When I was 9, my parents gave me a Commodore 64, which was fun. At the time, the opportunity to program your own computer was easier than it is today. Today there are significantly larger barriers because of the complexity built into computing.

When in many dissections, carried out as opportunity offered upon living animals, I first addressed my mind to seeing how I could discover the function and offices of the heart’s movement in animals through the use of my own eyes instead of through the books and writings of others, I kept finding the matter so truly hard and beset with difficulties that I all but thought, with Fracastoro, that the heart's movement had been understood by God alone.

When physiologists revealed the existence and functions of hormones they not only gave increased opportunities for the activities of biochemists but in particular gave a new charter to biochemical thought, and with the discovery of vitamins that charter was extended.

While our behavior is still significantly controlled by our genetic inheritance, we have, through our brains, a much richer opportunity to blaze new behavioral and cultural pathways on short timescales.

With advancing years new impressions do not enter so rapidly, nor are they so hospitably received… There is a gradual diminution of the opportunities for age to acquire fresh knowledge. A tree grows old not by loss of the vitality of the cambium, but by the gradual increase of the wood, the non-vital tissue, which so easily falls a prey to decay.

Would you have a man reason well, you must use him to it betimes; exercise his mind in observing the connection between ideas, and following them in train. Nothing does this better than mathematics, which therefore, I think should be taught to all who have the time and opportunity, not so much to make them mathematicians, as to make them reasonable creatures; for though we all call ourselves so, because we are born to it if we please, yet we may truly say that nature gives us but the seeds of it, and we are carried no farther than industry and application have carried us.