[Concerning] the usual contempt with which an orthodox analytic group treats all outsiders and strangers ... I urge you to think of the young psychoanalysts as your colleagues, collaborators and partners and not as spies, traitors and wayward children. You can never develop a science that way, only an orthodox church.

[In treating the sick], the first thing to consider is the provision of fresh air, clean water, and a healthy diet.

[Modern science] passed through a long period of uncertainty and inconclusive experiment, but as the instrumental aids to research improved, and the results of observation accumulated, phantoms of the imagination were exorcised, idols of the cave were shattered, trustworthy materials were obtained for logical treatment, and hypotheses by long and careful trial were converted into theories.

[Trousseau regarded as the chief aim of medicine:] Get that patient well.

Curando fieri quaedam majora videmus vulnera, quae melius non tetigisse fuit.
Some wounds are made worse by treatment, as we see: it had been better not to touch them.

Les grands ponts étant … des monuments qui peuvent servir à faire connoître la magnificence et le génie d’une nation, on ne sauroit trop s’occuper des moyens d’en perfectionner l’architecture, qui peut d’ailleurs être susceptible de variété, en conservant toujours, dans les formes et la décoration, le caractere de solidité qui lui est propre.
Great bridges being monuments which serve to make known the grandeur and genius of a nation, we cannot pay too much attention to means for perfecting their architecture; this may be varied in treatment, but there must ever be conserved, in form and in decoration, the indispensable character of solidity.

A doctor who cannot take a good history and a patient who cannot give one are in danger of giving and receiving bad treatment.

A new era of ocean exploration can yield discoveries that will help inform everything from critical medical advances to sustainable forms of energy. Consider that AZT, an early treatment for HIV, is derived from a Caribbean reef sponge, or that a great deal of energy—from offshore wind, to OTEC (ocean thermal energy conservation), to wind and wave energy—is yet untapped in our oceans.

A night with Venus, a lifetime with Mercury.
[For centuries mercury was used as a treatment for syphilis.]

A wealthy doctor who can help a poor man, and will not without a fee, has less sense of humanity than a poor ruffian who kills a rich man to supply his necessities. It is something monstrous to consider a man of a liberal education tearing out the bowels of a poor family by taking for a visit what would keep them a week.

Accordingly, we find Euler and D'Alembert devoting their talent and their patience to the establishment of the laws of rotation of the solid bodies. Lagrange has incorporated his own analysis of the problem with his general treatment of mechanics, and since his time M. Poinsôt has brought the subject under the power of a more searching analysis than that of the calculus, in which ideas take the place of symbols, and intelligent propositions supersede equations.

Across the road from my cabin was a huge clear-cut—hundreds of acres of massive spruce stumps interspersed with tiny Douglas firs—products of what they call “Reforestation,” which I guess makes the spindly firs en masse a “Reforest,” which makes an individual spindly fir a “Refir,” which means you could say that Weyerhauser, who owns the joint, has Refir Madness, since they think that sawing down 200-foot-tall spruces and replacing them with puling 2-foot Refirs is no different from farming beans or corn or alfalfa. They even call the towering spires they wipe from the Earth’s face forever a “crop”--as if they’d planted the virgin forest! But I'm just a fisherman and may be missing some deeper significance in their nomenclature and stranger treatment of primordial trees.

All sorts of computer errors are now turning up. You'd be surprised to know the number of doctors who claim they are treating pregnant men.

And if this were so in all cases, the principle would be established, that sometimes conditions can be treated by things opposite to those from which they arose, and sometimes by things like to those from which they arose.

As an adult she had her organs removed one by one. Now she is a mere shell with symptoms where her organs used to be.
Written as an intern on one of his patient's charts; commentary on the result of surgical treatment of non-organic disease.

Bearing in mind that it is from the vitality of the atmospheric particles that all the mischief arises, it appears that all that is requisite is to dress the wound with some material capable of killing these septic germs, provided that any substance can be found reliable for this purpose, yet not too potent as a caustic. In the course of the year 1864 I was much struck with an account of the remarkable effects produced by carbolic acid upon the sewage of the town of Carlisle, the admixture of a very small proportion not only preventing all odour from the lands irrigated with the refuse material, but, as it was stated, destroying the entozoa which usually infest cattle fed upon such pastures.

Before his [Sir Astley Cooper’s] time, operations were too often frightful alternatives or hazardous compromises; and they were not seldom considered rather as the resource of despair than as a means of remedy; he always made them follow, as it were, in the natural course of treatment; he gave them a scientific character; and he moreover, succeeded, in a great degree, in divesting them of their terrors, by performing them unostentatiously, simply, confidently, and cheerfully, and thereby inspiring the patient with hope of relief, where previously resignation under misfortune had too often been all that could be expected from the sufferer.

Body and soul cannot be separated for purposes of treatment, for they are one and indivisible. Sick minds must be healed as well as sick bodies.

But when it has been shown by the researches of Pasteur that the septic property of the atmosphere depended not on the oxygen, or any gaseous constituent, but on minute organisms suspended in it, which owed their energy to their vitality, it occurred to me that decomposition in the injured part might be avoided without excluding the air, by applying as a dressing some material capable of destroying the life of the floating particles. Upon this principle I have based a practice.

Calculation touches, at most, certain phenomena of organic destruction. Organic creation, on the contrary, the evolutionary phenomena which properly constitute life, we cannot in any way subject to a mathematical treatment.

Clinical ecology [is] a new branch of medicine aimed at helping people made sick by a failure to adapt to facets of our modern, polluted environment. Adverse reactions to processed foods and their chemical contaminants, and to indoor and outdoor air pollution with petrochemicals, are becoming more and more widespread and so far these reactions are being misdiagnosed by mainstream medical practitioners and so are not treated effectively.

Correct is to recognize what diseases are and whence they come; which are long and which are short; which are mortal and which are not; which are in the process of changing into others; which are increasing and which are diminishing; which are major and which are minor; to treat the diseases that can be treated, but to recognize the ones that cannot be, and to know why they cannot be; by treating patients with the former, to give them the benefit of treatment as far as it is possible.

Creation science has not entered the curriculum for a reason so simple and so basic that we often forget to mention it: because it is false, and because good teachers understand why it is false. What could be more destructive of that most fragile yet most precious commodity in our entire intellectual heritage—good teaching—than a bill forcing our honorable teachers to sully their sacred trust by granting equal treatment to a doctrine not only known to be false, but calculated to undermine any general understanding of science as an enterprise?.

Creative geniuses are a slap-happy lot. Treat Them with respect.

Detection is, or ought to be, an exact science, and should be treated in the same cold unemotional manner. You have attempted to tinge it with romanticism, which produces the same effect as if you worked a love-story into the fifth proposition of Euclid.

Diagnosis is not the end, but the beginning of practice.

Diseases can rarely be eliminated through early diagnosis or good treatment, but prevention can eliminate disease.

Doctor Johnson said, that in sickness there were three things that were material; the physician, the disease, and the patient: and if any two of these joined, then they get the victory; for, Ne Hercules quidem contra duos [Not even Hercules himself is a match for two]. If the physician and the patient join, then down goes the disease; for then the patient recovers: if the physician and the disease join, that is a strong disease; and the physician mistaking the cure, then down goes the patient: if the patient and the disease join, then down goes the physician; for he is discredited.

Euclid avoids it [the treatment of the infinite]; in modern mathematics it is systematically introduced, for only then is generality obtained.

Ever so often in the history of human endeavour, there comes a breakthrough that takes humankind across a frontier into a new era. ... today's announcement is such a breakthrough, a breakthrough that opens the way for massive advancement in the treatment of cancer and hereditary diseases. And that is only the beginning.

Evolutionary plasticity can be purchased only at the ruthlessly dear price of continuously sacrificing some individuals to death from unfavourable mutations. Bemoaning this imperfection of nature has, however, no place in a scientific treatment of this subject.

Experimental psychology itself has, it is true, now and again suffered relapse into a metaphysical treatment of its problems.

Few will deny that even in the first scientific instruction in mathematics the most rigorous method is to be given preference over all others. Especially will every teacher prefer a consistent proof to one which is based on fallacies or proceeds in a vicious circle, indeed it will be morally impossible for the teacher to present a proof of the latter kind consciously and thus in a sense deceive his pupils. Notwithstanding these objectionable so-called proofs, so far as the foundation and the development of the system is concerned, predominate in our textbooks to the present time. Perhaps it will be answered, that rigorous proof is found too difficult for the pupil’s power of comprehension. Should this be anywhere the case,—which would only indicate some defect in the plan or treatment of the whole,—the only remedy would be to merely state the theorem in a historic way, and forego a proof with the frank confession that no proof has been found which could be comprehended by the pupil; a remedy which is ever doubtful and should only be applied in the case of extreme necessity. But this remedy is to be preferred to a proof which is no proof, and is therefore either wholly unintelligible to the pupil, or deceives him with an appearance of knowledge which opens the door to all superficiality and lack of scientific method.

For want of timely care
Millions have died of medicable wounds.

Fourier’s Theorem … is not only one of the most beautiful results of modern analysis, but it may be said to furnish an indispensable instrument in the treatment of nearly every recondite question in modern physics. To mention only sonorous vibrations, the propagation of electric signals along a telegraph wire, and the conduction of heat by the earth’s crust, as subjects in their generality intractable without it, is to give but a feeble idea of its importance.

From the womb of darkness and cocoon of indifference is emerging a form of treatment that will eventually be added to the armamentarium of the alert and concerned physician.

Further study of the division phenomena requires a brief discussion of the material which thus far I have called the stainable substance of the nucleus. Since the term nuclear substance could easily result in misinterpretation..., I shall coin the term chromatin for the time being. This does not indicate that this substance must be a chemical compound of a definite composition, remaining the same in all nuclei. Although this may be the case, we simply do not know enough about the nuclear substances to make such an assumption. Therefore, we will designate as chromatin that substance, in the nucleus, which upon treatment with dyes known as nuclear stains does absorb the dye. From my description of the results of staining resting and dividing cells... it follows that the chromatin is distributed throughout the whole resting nucleus, mostly in the nucleoli, the network, and the membrane, but also in the ground-substance. In nuclear division it accumulates exclusively in the thread figures. The term achromatin suggests itself automatically for the unstainable substance of the nucleus. The terms chromatic and achromatic which will be used henceforth are thus explained.

General preparatory instruction must continue to be the aim in the instruction at the higher institutions of learning. Exclusive selection and treatment of subject matter with reference to specific avocations is disadvantageous.

Given one well-trained physician of the highest type and he will do better work for a thousand people than ten specialists.

He will manage the cure best who has foreseen what is to happen from the present state of matters.

Here’s good advice for practice: go into partnership with nature; she does more than half the work and asks none of the fee.

I believe that natural history has lost much by the vague general treatment that is so common.

I believe that the medical treatment of the various abnormal conditions arising in infants is in the future to be largely dietetic rather than by means of drugs.

I believe that, as men occupied with the study and treatment of disease, we cannot have too strong a conviction that the problems presented to us are physical problems, which perhaps we may never solve, but still admitting of solution only in one way, namely, by regarding them as part of an unbroken series, running up from the lowest elementary conditions of matter to the highest composition of organic structure.

I devoted myself especially to the purification of the radium…. It was only after treating one ton of pitchblende residues that I could get definite results. Indeed we know to-day that even in the best minerals there are not more than a few decigrammes of radium in a ton of raw material.

I devoted myself to studying the texts—the original and commentaries—in the natural sciences and metaphysics, and the gates of knowledge began opening for me. Next I sought to know medicine, and so read the books written on it. Medicine is not one of the difficult sciences, and therefore, I excelled in it in a very short time, to the point that distinguished physicians began to read the science of medicine under me. I cared for the sick and there opened to me some of the doors of medical treatment that are indescribable and can be learned only from practice. In addition I devoted myself to jurisprudence and used to engage in legal disputations, at that time being sixteen years old.

I don’t know if I would call it a miracle. I would call it a spectacular example of what people can do. To me, it’s like putting the first man on the moon or splitting the atom. We’ve shown that if the right treatment is given to people who have a catastrophic injury that they could walk away from it.
Expressing optimism for further recovery for Kevin Everett, a Buffalo Bills football player who suffered a paralyzing spinal injury during a game (9 Sep 2007), but after two days of hospital treatment had begun voluntarily moving his arms and legs. Green credits as significant to the recovery was that within minutes of his injury, the patient was quickly treated with intravenous ice-cold saline solution to induce hypothermia.

I have lived myself to see the disciples of Hoffman, Boerhaave, Stalh, Cullen, Brown, succeed one another like the shifting figures of a magic lanthern, and their fancies, like the dresses of the annual doll-babies from Paris, becoming from their novelty, the vogue of the day, and yielding to the next novelty their ephemeral favor. The patient, treated on the fashionable theory, sometimes gets well in spite of the medicine.

I look upon statistics as the handmaid of medicine, but on that very account I hold that it befits medicine to treat her handmaid with proper respect, and not to prostitute her services for controversial or personal purposes.

I take it that a monograph of this sort belongs to the ephemera literature of science. The studied care which is warranted in the treatment of the more slowly moving branches of science would be out of place here. Rather with the pen of a journalist we must attempt to record a momentary phase of current thought, which may at any instant change with kaleidoscopic abruptness.

I think it perfectly just, that he who, from the love of experiment, quits an approved for an uncertain practice, should suffer the full penalty of Egyptian law against medical innovation; as I would consign to the pillory, the wretch, who out of regard to his character, that is, to his fees, should follow the routine, when, from constant experience he is sure that his patient will die under it, provided any, not inhuman, deviation would give his patient a chance.

I trust I may be enabled in the treatment of patients always to act with a single eye to their good.

I waited for Rob and, linking arms, we took our final steps together onto the rooftop of the world. It was 8.15 am on 24 May 2004; there was nowhere higher on the planet that we could go, the world lay at our feet. Holding each other tightly, we tried to absorb where we were. To be standing here, together, exactly three years since Rob’s cancer treatment, was nothing short of a miracle. Standing on top of Everest was more than just climbing a mountain - it was a gift of life. With Pemba and Nawang we crowded together, wrapping our arms around each other. They had been more than Sherpas, they had been our guardian angels.

I wish I had my beta-blockers handy.
[Comment when told that he had won a Nobel prize, referring to the drug he discovered for the treatment of heart disease.]

If gold medals and prizes were awarded to institutions instead of individuals, the Peter Bent Brigham Hospital of 30 years ago would have qualified. The ruling board and administrative structure of that hospital did not falter in their support of the quixotic objective of treating end-stage renal disease despite a long list of tragic failures that resulted from these early efforts.

If the just cure of a disease be full of peril, let the physician resort to palliation.

If the study of all these sciences which we have enumerated, should ever bring us to their mutual association and relationship, and teach us the nature of the ties which bind them together, I believe that the diligent treatment of them will forward the objects which we have in view, and that the labor, which otherwise would be fruitless, will be well bestowed.

If there is a just God, how humanity would writhe in its attempt to justify its treatment of animals.

If these d'Hérelle bodies were really genes, fundamentally like our chromosome genes, they would give us an utterly new angle from which to attack the gene problem. They are filterable, to some extent isolable, can be handled in test-tubes, and their properties, as shown by their effects on the bacteria, can then be studied after treatment. It would be very rash to call these bodies genes, and yet at present we must confess that there is no distinction known between the genes and them. Hence we can not categorically deny that perhaps we may be able to grind genes in a mortar and cook them in a beaker after all. Must we geneticists become bacteriologists, physiological chemists and physicists, simultaneously with being zoologists and botanists? Let us hope so.

If thou examinest a man having a break in the column of his nose, his nose being disfigured, and a [depression] being in it, while the swelling that is on it protrudes, [and] he had discharged blood from both his nostrils, thou shouldst say concerning him: “One having a break in the column of his nose. An ailment which I will treat. “Thou shouldst cleanse [it] for him [with] two plugs of linen. Thou shouldst place two [other] plugs of linen saturated with grease in the inside of his two nostrils. Thou shouldst put [him] at his mooring stakes until the swelling is drawn out. Thou shouldst apply for him stiff rolls of linen by which his nose is held fast. Thou shouldst treat him afterward [with] lint, every day until he recovers.

Immediately south of nitrogen is phosphorus, which was first isolated by the distillation and treatment of urine—an indication of the lengths to which chemists are prepared to go, or perhaps only a sign of the obsessive, scatological origins of their vocation.

In Euclid each proposition stands by itself; its connection with others is never indicated; the leading ideas contained in its proof are not stated; general principles do not exist. In modern methods, on the other hand, the greatest importance is attached to the leading thoughts which pervade the whole; and general principles, which bring whole groups of theorems under one aspect, are given rather than separate propositions. The whole tendency is toward generalization. A straight line is considered as given in its entirety, extending both ways to infinity, while Euclid is very careful never to admit anything but finite quantities. The treatment of the infinite is in fact another fundamental difference between the two methods. Euclid avoids it, in modern mathematics it is systematically introduced, for only thus is generality obtained.

In psychoanalytic treatment nothing happens but an exchange of words between the patient and the physician.

In reality, I have sometimes thought that we do not go on sufficiently slowly in the removal of diseases, and that it would he better if we proceeded with less haste, and if more were often left, to Nature than is the practice now-a-days. It is a great mistake to suppose that Nature always stands in need of the assistance of Art. If that were the case, site would have made less provision for the safety of mankind than the preservation of the species demands; seeing that there is not the least proportion between the host of existing diseases and the powers possessed by man for their removal, even in those ages wherein the healing art was at the highest pitch, and most extensively cultivated.

In scientific investigations it is grievously wrong to pander to the public’s impatience for results, or to let them think that for discovery it is necessary only to set up a great manufactory and a system of mass production. If in treatment team work is effective, in research it is the individual who counts first and above all. No great thought has ever sprung from anything but a single mind, suddenly conceiving. Throughout the whole world there has been too violent a forcing of the growth of ideas; too feverish a rush to perform experiments and publish conclusions. A year of vacation for calm detachment with all the individual workers thinking it all over in a desert should be proclaimed.

In the fight which we have to wage incessantly against ignorance and quackery among the masses and follies of all sorts among the classes, diagnosis, not drugging, is our chief weapon of offence. Lack of systematic personal training in the methods of the recognition of disease leads to the misapplication of remedies, to long courses of treatment when treatment is useless, and so directly to that lack of confidence in our methods which is apt to place us in the eyes of the public on a level with empirics and quacks.

In the sick room, ten cents’ worth of human understanding equals ten dollars' worth of medical science.

Insulin is not a cure for diabetes; it is a treatment. It enables the diabetic to burn sufficient carbohydrates, so that proteins and fats may be added to the diet in sufficient quantities to provide energy for the economic burdens of life.

It has been demonstrated that a species of penicillium produces in culture a very powerful antibacterial substance which affects different bacteria in different degrees. Generally speaking it may be said that the least sensitive bacteria are the Gram-negative bacilli, and the most susceptible are the pyogenic cocci ... In addition to its possible use in the treatment of bacterial infections penicillin is certainly useful... for its power of inhibiting unwanted microbes in bacterial cultures so that penicillin insensitive bacteria can readily be isolated.

It is a common observation that a science first begins to be exact when it is quantitatively treated. What are called the exact sciences are no others than the mathematical ones.

It is a curious and painful fact that almost all the completely futile treatments that have been believed in during the long history of medical folly have been such as caused acute suffering to the patient. When anesthetics were discovered, pious people considered them an attempt to evade the will of God. It was pointed out, however, that when God extracted Adam's rib He put him into a deep sleep. This proved that anesthetics are all right for men; women, however, ought to suffer, because of the curse of Eve.

It is customary to connect Medicine with Botany, yet scientific treatment demands that we should consider each separately. For the fact is that in every art, theory must be disconnected and separated from practice, and the two must be dealt with singly and individually in their proper order before they are united. And for that reason, in order that Botany, which is, as it were, a special branch of Natural Philosophy [Physica], may form a unit by itself before it can be brought into connection with other sciences, it must be divided and unyoked from Medicine.

It is my belief that the basic knowledge that we're providing to the world will have a profound impact on the human condition and the treatments for disease and our view of our place on the biological continuum.

It is not only a decided preference for synthesis and a complete denial of general methods which characterizes the ancient mathematics as against our newer Science [modern mathematics]: besides this extemal formal difference there is another real, more deeply seated, contrast, which arises from the different attitudes which the two assumed relative to the use of the concept of variability. For while the ancients, on account of considerations which had been transmitted to them from the Philosophie school of the Eleatics, never employed the concept of motion, the spatial expression for variability, in their rigorous system, and made incidental use of it only in the treatment of phonoromically generated curves, modern geometry dates from the instant that Descartes left the purely algebraic treatment of equations and proceeded to investigate the variations which an algebraic expression undergoes when one of its variables assumes a continuous succession of values.

It is not surprising that our language should be incapable of describing the processes occurring within the atoms, for, as has been remarked, it was invented to describe the experiences of daily life, and these consists only of processes involving exceedingly large numbers of atoms. Furthermore, it is very difficult to modify our language so that it will be able to describe these atomic processes, for words can only describe things of which we can form mental pictures, and this ability, too, is a result of daily experience. Fortunately, mathematics is not subject to this limitation, and it has been possible to invent a mathematical scheme—the quantum theory—which seems entirely adequate for the treatment of atomic processes; for visualization, however, we must content ourselves with two incomplete analogies—the wave picture and the corpuscular picture.

It is one of the signs of the times that modern chemists hold themselves bound and consider themselves in a position to give an explanation for everything, and when their knowledge fails them to make sure of supernatural explanations. Such a treatment of scientific subjects, not many degrees removed from a belief in witches and spirit-rapping, even Wislicenus considers permissible.

It is possible to read books on Natural History with intelligence and profit, and even to make good observations, without a scientific groundwork of biological instruction; and it is possible to arrive at empirical facts of hygiene and medical treatment without any physiological instruction. But in all three cases the absence of a scientific basis will render the knowledge fragmentary and incomplete; and this ought to deter every one from offering an opinion on debatable questions which pass beyond the limit of subjective observations. The psychologist who has not prepared himself by a study of the organism has no more right to be heard on the genesis of the psychical states, or of the relations between body and mind, than one of the laity has a right to be heard on a question of medical treatment.

It seeming impossible in any other manner to properly restrict the use of this powerful agent [calomel, a mercury compound, mercurous chloride], it is directed that it be struck from the supply table, and that no further requisitions for this medicine be approved by Medical Directors. ... modern pathology has proved the impropriety of the use of mercury in very many of those diseases in which it was formerly unfailingly administered. ... No doubt can exist that more harm has resulted from the misuse [of this agent], in the treatment of disease, than benefit from their proper administration.
W.A. Hammond, Surgeon General, Washington D.C., 4 May 1863

It would be impossible, it would be against the scientific spirit. … Physicists should always publish their researches completely. If our discovery has a commercial future that is a circumstance from which we should not profit. If radium is to be used in the treatment of disease, it is impossible for us to take advantage of that.

Knowing, henceforth, the physiognomy of the disease when allowed to run its own course, you can, without risk of error, estimate the value of the different medications which have been employed. You will discover which remedies have done no harm, and which have notably curtailed the duration of the disease; and thus for the future you will have a standard by which to measure the value of the medicine which you see employed to counteract the malady in question. What you have done in respect of one disease, you will be able to do in respect of many; and by proceeding in this way you will be able, on sure data, to pass judgment on the treatment pursued by your masters.

Let out the blood, let out the disease.

Let the surgeon take care to regulate the whole regimen of the patient's life for joy and happiness by promising that he will soon be well, by allowing his relatives and special friends to cheer him and by having someone tell him jokes, and let him be solaced also by music on the viol or psaltery. The surgeon must forbid anger, hatred, and sadness in the patient, and remind him that the body grows fat from joy and thin from sadness.

Let us now discuss the extent of the mathematical quality in Nature. According to the mechanistic scheme of physics or to its relativistic modification, one needs for the complete description of the universe not merely a complete system of equations of motion, but also a complete set of initial conditions, and it is only to the former of these that mathematical theories apply. The latter are considered to be not amenable to theoretical treatment and to be determinable only from observation.

Like other addictions, tobacco use can be effectively treated. A wide variety of behavioral interventions have been used for years. In recognition of the important role that nicotine plays in maintaining tobacco use, nicotine replacement therapy is now available. Nicotine gum has been shown to relieve withdrawal symptoms following smoking cessation, and may enhance the effectiveness of behavioral treatments. These treatment measures should be made more widely available to smokers who need them. Unfortunately most party payors do not provide coverage for smoking cessation treatments. On the other hand, treatment for alcoholism and illicit drug use is often covered. And we should eliminate this double standard.

Many a diabetic has stayed alive by stealing the bread denied him by his doctor.

Many more Englishmen die by the lancet at home,
than by the sword abroad.

Medical men do not know the drugs they use, nor their prices.

Medical science has proven time and again that when the resources are provided, great progress in the treatment, cure and prevention of disease can occur.

Men today who have had an irreproachable training in the art are seen to abstain from the use of the hand as from the plague, and for this very reason, lest they should be slandered by the masters of the profession as barbers… . For it is indeed above all things the wide prevalence of this hateful error that prevents us even in our age from taking up the healing art as a whole, makes us confine ourselves merely to the treatment of internal complaints, and, if I may utter the blunt truth once for all, causes us, to the great detriment of mankind, to study to be healers only in a very limited degree.

Mr. Bertrand Russell tells us that it can be shown that a mathematical web of some kind can be woven about any universe containing several objects. If this be so, then the fact that our universe lends itself to mathematical treatment is not a fact of any great philosophical significance.

My visceral perception of brotherhood harmonizes with our best modern biological knowledge ... Many people think (or fear) that equality of human races represents a hope of liberal sentimentality probably squashed by the hard realities of history. They are wrong. This essay can be summarized in a single phrase, a motto if you will: Human equality is a contingent fact of history. Equality is not true by definition; it is neither an ethical principle (though equal treatment may be) nor a statement about norms of social action. It just worked out that way. A hundred different and plausible scenarios for human history would have yielded other results (and moral dilemmas of enormous magnitude). They didn’t happen.

Never forget that it is not a pneumonia, but a pneumonic man who is your patient.

No disease that can be treated by diet should be treated by any other means.

Not one idiot in a thousand has been entirely refractory to treatment, not one in a hundred has not been made more happy and healthy; more than thirty per cent have been taught to conform to social and moral law, and rendered capable of order, of good feeling, and of working like the third of a man; more than forty per cent have become capable of the ordinary transactions of life under friendly control, of understanding moral and social abstractions, of working like two-thirds of a man.

Nowadays the clinical history too often weighs more than the man.

Ohm (a distinguished mathematician, be it noted) brought into order a host of puzzling facts connecting electromotive force and electric current in conductors, which all previous electricians had only succeeded in loosely binding together qualitatively under some rather vague statements. Even as late as 20 years ago, “quantity” and “tension” were much used by men who did not fully appreciate Ohm's law. (Is it not rather remarkable that some of Germany's best men of genius should have been, perhaps, unfairly treated? Ohm; Mayer; Reis; even von Helmholtz has mentioned the difficulty he had in getting recognised. But perhaps it is the same all the world over.)

On the 20th of May 1747, I took twelve patients in the scurvy, on board the Salisbury at sea. Their cases were as similar as I could have them. They all in general had putrid gums, the spots and lassitude, with weakness of their knees. They lay together in one place, being a proper apartment for the sick in the fore-hold; and had one diet common to all, viz, water-gruel sweetened with sugar in the morning; fresh mutton-broth often times for dinner; at other times puddings, boiled biscuit with sugar, &c.; and for supper, barley and raisins, rice and currents, sago and wine, or the like.
Two of these were ordered each a quart of cider a-day. Two others took twenty-five gutta of elixir vitriol three times a-day, upon an empty stomach; using a gargle strongly acidulated with it for their mouths. Two others took two spoonfuls of vinegar three times a-day, upon an empty stomach; having their gruels and their other food well acidulated with it, as also the gargle for their mouth. Two of the worst patients, with the tendons in the ham rigid, (a symptom none of the rest had), were put under a course of sea-water. Of this they drank half a pint every day, and sometimes more or less as it operated, by way of gentle physics. The others had each two oranges and one lemon given them every day. These they eat with greediness, at different times, upon an empty stomach. They continued but six days under this course, having consumed the quantity that could be spared. The two remaining patients, took the bigness of a nutmeg three times a-day, of an electuary recommended by an hospital-surgeon, made of garlic, mustard-seed, rad. raphan. balsam of Peru, and gum myrrh; using for common drink, barley-water well acidulated with tamarinds; by a decoction of which, with the addition of cremor tartar, they were gently purged three or four times during the course.
The consequence was, that the most sudden and visible good effects were perceived from the use of the oranges and lemons; one of those who had taken them, being at the end of six days fit for duty. …
Next to the oranges, I thought the cider had the best effects.

Only one rule in medical ethics need concern you - that action on your part which best conserves the interests of your patient.

Our treatment of this science will be adequate, if it achieves the amount of precision which belongs to its subject matter.

Owing to his lack of knowledge, the ordinary man cannot attempt to resolve conflicting theories of conflicting advice into a single organized structure. He is likely to assume the information available to him is on the order of what we might think of as a few pieces of an enormous jigsaw puzzle. If a given piece fails to fit, it is not because it is fraudulent; more likely the contradictions and inconsistencies within his information are due to his lack of understanding and to the fact that he possesses only a few pieces of the puzzle. Differing statements about the nature of things, differing medical philosophies, different diagnoses and treatments—all of these are to be collected eagerly and be made a part of the individual's collection of puzzle pieces. Ultimately, after many lifetimes, the pieces will fit together and the individual will attain clear and certain knowledge.

Palliative care should be an integral part of cancer care and not be associated exclusively with terminal care. Many patients need it early in the course of their disease.

Science affects the average man and woman in two ways already. He or she benefits by its application driving a motor-car or omnibus instead of a horse-drawn vehicle, being treated for disease by a doctor or surgeon rather than a witch, and being killed with an automatic pistol or shell in place of a dagger or a battle-axe.

Science and Theology. We should endow neither; we should treat them as we treat conservatism and liberalism, encouraging both, so that they may keep watch upon one another, and letting them go in and out of power with the popular vote concerning them

Scientific training gives its votaries freedom from the impositions of modern quackery. Those who know nothing of the laws and processes of Nature fall an easy prey to quacks and impostors. Perfectionism in the realm of religion; a score of frauds in the realm of medicine, as electric shoe soles, hair brushes and belts, electropises, oxydonors, insulating bed casters, and the like; Christian science, in the presence of whose unspeakable stillness and self-stultifying idealism a wise man knows not whether to laugh or cry; Prof. Weltmer’s magnetic treatment of disease; divine healing and miracle working by long-haired peripatetics—these and a score of other contagious fads and rank impostures find their followers among those who have no scientific training. Among their deluded victims are thousands of men and women of high character, undoubted piety, good intentions, charitable impulses and literary culture, but none trained to scientific research. Vaccinate the general public with scientific training and these epidemics will become a thing of the past.

Scientists and particularly the professional students of evolution are often accused of a bias toward mechanism or materialism, even though believers in vitalism and in finalism are not lacking among them. Such bias as may exist is inherent in the method of science. The most successful scientific investigation has generally involved treating phenomena as if they were purely materialistic, rejecting any metaphysical hypothesis as long as a physical hypothesis seems possible. The method works. The restriction is necessary because science is confined to physical means of investigation and so it would stultify its own efforts to postulate that its subject is not physical and so not susceptible to its methods.

The actual evolution of mathematical theories proceeds by a process of induction strictly analogous to the method of induction employed in building up the physical sciences; observation, comparison, classification, trial, and generalisation are essential in both cases. Not only are special results, obtained independently of one another, frequently seen to be really included in some generalisation, but branches of the subject which have been developed quite independently of one another are sometimes found to have connections which enable them to be synthesised in one single body of doctrine. The essential nature of mathematical thought manifests itself in the discernment of fundamental identity in the mathematical aspects of what are superficially very different domains. A striking example of this species of immanent identity of mathematical form was exhibited by the discovery of that distinguished mathematician … Major MacMahon, that all possible Latin squares are capable of enumeration by the consideration of certain differential operators. Here we have a case in which an enumeration, which appears to be not amenable to direct treatment, can actually be carried out in a simple manner when the underlying identity of the operation is recognised with that involved in certain operations due to differential operators, the calculus of which belongs superficially to a wholly different region of thought from that relating to Latin squares.

The appearance of a disease is swift as an arrow; its disappearance slow, like a thread.

The difficulties connected with my criterion of demarcation (D) are important, but must not be exaggerated. It is vague, since it is a methodological rule, and since the demarcation between science and nonscience is vague. But it is more than sharp enough to make a distinction between many physical theories on the one hand, and metaphysical theories, such as psychoanalysis, or Marxism (in its present form), on the other. This is, of course, one of my main theses; and nobody who has not understood it can be said to have understood my theory.
The situation with Marxism is, incidentally, very different from that with psychoanalysis. Marxism was once a scientific theory: it predicted that capitalism would lead to increasing misery and, through a more or less mild revolution, to socialism; it predicted that this would happen first in the technically highest developed countries; and it predicted that the technical evolution of the 'means of production' would lead to social, political, and ideological developments, rather than the other way round.
But the (so-called) socialist revolution came first in one of the technically backward countries. And instead of the means of production producing a new ideology, it was Lenin's and Stalin's ideology that Russia must push forward with its industrialization ('Socialism is dictatorship of the proletariat plus electrification') which promoted the new development of the means of production.
Thus one might say that Marxism was once a science, but one which was refuted by some of the facts which happened to clash with its predictions (I have here mentioned just a few of these facts).
However, Marxism is no longer a science; for it broke the methodological rule that we must accept falsification, and it immunized itself against the most blatant refutations of its predictions. Ever since then, it can be described only as nonscience—as a metaphysical dream, if you like, married to a cruel reality.
Psychoanalysis is a very different case. It is an interesting psychological metaphysics (and no doubt there is some truth in it, as there is so often in metaphysical ideas), but it never was a science. There may be lots of people who are Freudian or Adlerian cases: Freud himself was clearly a Freudian case, and Adler an Adlerian case. But what prevents their theories from being scientific in the sense here described is, very simply, that they do not exclude any physically possible human behaviour. Whatever anybody may do is, in principle, explicable in Freudian or Adlerian terms. (Adler's break with Freud was more Adlerian than Freudian, but Freud never looked on it as a refutation of his theory.)
The point is very clear. Neither Freud nor Adler excludes any particular person's acting in any particular way, whatever the outward circumstances. Whether a man sacrificed his life to rescue a drowning, child (a case of sublimation) or whether he murdered the child by drowning him (a case of repression) could not possibly be predicted or excluded by Freud's theory; the theory was compatible with everything that could happen—even without any special immunization treatment.
Thus while Marxism became non-scientific by its adoption of an immunizing strategy, psychoanalysis was immune to start with, and remained so. In contrast, most physical theories are pretty free of immunizing tactics and highly falsifiable to start with. As a rule, they exclude an infinity of conceivable possibilities.

The frequency of disastrous consequences in compound fracture, contrasted with the complete immunity from danger to life or limb in simple fracture, is one of the most striking as well as melancholy facts in surgical practice.

The fundamental laws necessary for the mathematical treatment of a large part of physics and the whole of chemistry are thus completely known, and the difficulty lies only in the fact that application of these laws leads to equations that are too complex to be solved.

The greatest possibility of evil in self-medication [with penicillin] is the use of too-small doses, so that, instead of clearing up the infection, the microbes are educated to resist penicillin and a host of penicillin-fast organisms is bred out which can be passed on to other individuals and perhaps from there to others until they reach someone who gets a septicemia or a pneumonia which penicillin cannot save. In such a case the thoughtless person playing with penicillin treatment is morally responsible for the death of the man who finally succumbs to infection with the penicillin-resistant organism. I hope this evil can be averted.

The history of acceptance of new theories frequently shows the following steps: At first the new idea is treated as pure nonsense, not worth looking at. Then comes a time when a multitude of contradictory objections are raised, such as: the new theory is too fancy, or merely a new terminology; it is not fruitful, or simply wrong. Finally a state is reached when everyone seems to claim that he had always followed this theory. This usually marks the last state before general acceptance.

The inclusion of lemon or lime juice in grog, made compulsory in 1795, therefore reduced the incidence of scurvy dramatically. And since beer contains no vitamin C, switching from beer to grog made British crews far healthier overall.

The more I study the things of the mind the more mathematical I find them. In them as in mathematics it is a question of quantities; they must be treated with precision. I have never had more satisfaction than in proving this in the realms of art, politics and history.

The natural scientist is concerned with a particular kind of phenomena … he has to confine himself to that which is reproducible … I do not claim that the reproducible by itself is more important than the unique. But I do claim that the unique exceeds the treatment by scientific method. Indeed it is the aim of this method to find and test natural laws…

The only English patients I have ever known refuse tea, have been typhus cases; and the first sign of their getting better was their craving again for tea.

The patient has two sleeves, one containing a diagnostic and the other a therapeutic armamentarium; these sleeves should rarely be emptied in one move; keep some techniques in reserve; time your manoeuvres to best serve the status and special needs of your patient.

The prime goal is to alleviate suffering, and not to prolong life. And if your treatment does not alleviate suffering, but only prolongs life, that treatment should be stopped.

The principles of medical management are essentially the same for individuals of all ages, albeit the same problem is handled differently in different patients. ... [just as] the principles of driving an automobile are uniform, but one drives in one manner on the New Jersey Turnpike and in another manner on a narrow, winding road in the Rocky Mountains.

The realization of the role played by DNA has had absolutely no consequence for either therapy or prevention…. Treatments for cancer remain today what they were before molecular biology was ever thought of: cut it out, burn it out, or poison it.

The rich can pay when they have to pay [for medical care]. The poor receive free treatment from skilled specialists and can go, when necessary, to hospitals free of charge. But between seventy-five and ninety per cent. of our population, that which constitutes our very backbone, find it difficult to be relieved from the intolerable burden of illness.

The rudest numerical scales, such as that by which the mineralogists distinguish different degrees of hardness, are found useful. The mere counting of pistils and stamens sufficed to bring botany out of total chaos into some kind of form. It is not, however, so much from counting as from measuring, not so much from the conception of number as from that of continuous quantity, that the advantage of mathematical treatment comes. Number, after all, only serves to pin us down to a precision in our thoughts which, however beneficial, can seldom lead to lofty conceptions, and frequently descend to pettiness.

The science of medicine is founded on conjecture, and improved by murder.
[Lamenting the deadly consequences of blind ignorance in medical treatments.]

The surgeon is a man of action. By temperament and by training he prefers to serve the sick by operating on them, and he inwardly commiserates with a patient so unfortunate as to have a disease not suited to surgical treatment. Young surgeons, busy mastering the technicalities of the art, are particularly alert to seize every legitimate opportunity to practice technical maneuvers, the more complicated the better.

The theory of medicine, therefore, presents what is useful in thought, but does not indicate how it is to be applied in practice—the mode of operation of these principles. The theory, when mastered, gives us a certain kind of knowledge. Thus we say, for example, there are three forms of fevers and nine constitutions. The practice of medicine is not the work which the physician carries out, but is that branch of medical knowledge which, when acquired, enables one to form an opinion upon which to base the proper plan of treatment.

There are many good general practitioners, there is only one good universal practitioner—“a warm bed.”

There are some modern practitioners, who declaim against medical theory in general, not considering that to think is to theorize; and that no one can direct a method of cure to a person labouring under disease, without thinking, that is, without theorizing; and happy therefore is the patient, whose physician possesses the best theory.

There is a science which investigates being as being and the attributes which belong to this in virtue of its own nature. Now this is not the same as any of the so-called special sciences; for none of these treats universally of being as being. They cut off a part of being and investigate the attribute of this part; this is what the mathematical sciences for instance do. Now since we are seeking the first principles and the highest causes, clearly there must be some thing to which these belong in virtue of its own nature. If then those who sought the elements of existing things were seeking these same principles, it is necessary that the elements must be elements of being not by accident but just because it is being. Therefore it is of being as being that we also must grasp the first causes.

There is at bottom only one genuinely scientific treatment for all diseases, and that is to stimulate the phagocytes.

To array a man's will against his sickness is the supreme art of medicine.

To fully understand the mathematical genius of Sophus Lie, one must not turn to books recently published by him in collaboration with Dr. Engel, but to his earlier memoirs, written during the first years of his scientific career. There Lie shows himself the true geometer that he is, while in his later publications, finding that he was but imperfectly understood by the mathematicians accustomed to the analytic point of view, he adopted a very general analytic form of treatment that is not always easy to follow.

To those … engaged in the practice of medicine, the study of Physiology is indispensable; for it is evident that the nature of the disordered actions of parts or organs can never be understood, nor judiciously counteracted, unless the nature of their healthy actions be previously known.

We are a caring nation, and our values should also guide us on how we harness the gifts of science. New medical breakthroughs bring the hope of cures for terrible diseases and treatments that can improve the lives of millions. Our challenge is to make sure that science serves the cause of humanity instead of the other way around.

When a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. … Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.

When you see the natural and almost universal craving in English sick for their 'tea,' you cannot but feel that nature knows what she is about. … [A] little tea or coffee restores them. … [T]here is nothing yet discovered which is a substitute to the English patient for his cup of tea.