Present Quotes (630 quotes)
… the embryological record, as it is usually presented to us, is both imperfect and misleading. It may be compared to an ancient manuscript, with many of the sheets lost, others displaced, and with spurious passages interpolated by a later hand. … Like the scholar with his manuscript, the embryologist has by a process of careful and critical examination to determine where the gaps are present, to detect the later insertions, and to place in order what has been misplaced.
...Outer space, once a region of spirited international competition, is also a region of international cooperation. I realized this as early as 1959, when I attended an international conference on cosmic radiation in Moscow. At this conference, there were many differing views and differing methods of attack, but the problems were common ones to all of us and a unity of basic purpose was everywhere evident. Many of the papers presented there depended in an essential way upon others which had appeared originally in as many as three or four different languages. Surely science is one of the universal human activities.
…resort to science has rendered modern war so destructive of life and property that it presents a new problem to mankind, such, that unless our civilization shall find some means of making an end to war, war will make an end to our civilization.
…The present revolution of scientific thought follows in natural sequence on the great revolutions at earlier epochs in the history of science. Einstein’s special theory of relativity, which explains the indeterminateness of the frame of space and time, crowns the work of Copernicus who first led us to give up our insistence on a geocentric outlook on nature; Einstein's general theory of relativity, which reveals the curvature or non-Euclidean geometry of space and time, carries forward the rudimentary thought of those earlier astronomers who first contemplated the possibility that their existence lay on something which was not flat. These earlier revolutions are still a source of perplexity in childhood, which we soon outgrow; and a time will come when Einstein’s amazing revelations have likewise sunk into the commonplaces of educated thought.
...the scientific cast of mind examines the world critically, as if many alternative worlds might exist, as if other things might be here which are not. Then we are forced to ask why what we see is present and not something else. Why are the Sun and moon and the planets spheres? Why not pyramids, or cubes, or dodecahedra? Why not irregular, jumbly shapes? Why so symmetrical, worlds? If you spend any time spinning hypotheses, checking to see whether they make sense, whether they conform to what else we know. Thinking of tests you can pose to substantiate or deflate hypotheses, you will find yourself doing science.
...those experiments be not only esteemed which have an immediate and present use, but those principally which are of most universal consequence for invention of other experiments, and those which give more light to the invention of causes; for the invention of the mariner's needle, which giveth the direction, is of no less benefit for navigation than the invention of the sails, which give the motion.
“Unless,” said I [Socrates], “either philosophers become kings in our states or those whom we now call our kings and rulers take to the pursuit of' philosophy seriously and adequately, and there is a conjunction of these two things, political power and philosophic intelligence, while the motley horde of the natures who at present pursue either apart from the other are compulsorily excluded, there can be no cessation of troubles, dear Glaucon, for our states, nor, I fancy for the human race either. Nor, until this happens, will this constitution which we have been expounding in theory ever be put into practice within the limits of possibility and see the light of the sun.”
— Plato
[E.H.] Moore was presenting a paper on a highly technical topic to a large gathering of faculty and graduate students from all parts of the country. When half way through he discovered what seemed to be an error (though probably no one else in the room observed it). He stopped and re-examined the doubtful step for several minutes and then, convinced of the error, he abruptly dismissed the meeting—to the astonishment of most of the audience. It was an evidence of intellectual courage as well as honesty and doubtless won for him the supreme admiration of every person in the group—an admiration which was in no wise diminished, but rather increased, when at a later meeting he announced that after all he had been able to prove the step to be correct.
[Edison] definitely ended the distinction between the theoretical man of science and the practical man of science, so that today we think of scientific discoveries in connection with their possible present or future application to the needs of man. He took the old rule-of-thumb methods out of industry and substituted exact scientific knowledge, while, on the other hand, he directed scientific research into useful channels.
[F. Werner, while a student in Princeton,] came to me and expressed his bewilderment with the fact that we make a rather narrow selection when choosing the data on which we test our theories. “How do we know that, if we made a theory which focuses its attention on phenomena we disregard and disregards some of the phenomena now commanding our attention, that we could not build another theory which has little in common with the present one but which, nevertheless, explains just as many phenomena as the present theory?” It has to be admitted that we have no definite evidence that there is no such theory.
[From uranium] there are present at least two distinct types of radiation one that is very readily absorbed, which will be termed for convenience the α radiation, and the other of a more penetrative character, which will be termed the β radiation.
[I]t is truth alone—scientific, established, proved, and rational truth—which is capable of satisfying nowadays the awakened minds of all classes. We may still say perhaps, 'faith governs the world,'—but the faith of the present is no longer in revelation or in the priest—it is in reason and in science.
[Microscopic] evidence cannot be presented ad populum. What is seen with the microscope depends not only upon the instrument and the rock-section, but also upon the brain behind the eye of the observer. Each of us looks at a section with the accumulated experience of his past study. Hence the veteran cannot make the novice see with his eyes; so that what carries conviction to the one may make no appeal to the other. This fact does not always seem to be sufficiently recognized by geologists at large.
[My Book] will endeavour to establish the principle[s] of reasoning in ... [geology]; and all my geology will come in as illustration of my views of those principles, and as evidence strengthening the system necessarily arising out of the admission of such principles, which... are neither more nor less than that no causes whatever have from the earliest time to which we can look back, to the present, ever acted, but those now acting; and that they never acted with different degrees of energy from that which they now exert.
[O]ur own existence once presented the greatest of all mysteries, but … it is a mystery no longer because it is solved. Darwin and Wallace solved it … I was surprised that so many people seemed not only unaware of the elegant and beautiful solution to this deepest of problems but, incredibly, in many cases actually unaware that there was a problem in the first place!
[On gold, silver, mercury, platinum, palladium, rhodium, iridium, osmium:] As in their physical properties so in their chemical properties. Their affinities being weaker, (the noble metals) do not present that variety of combinations, belonging to the more common metals, which renders them so extensively useful in the arts; nor are they, in consequence, so necessary and important in the operations of nature. They do not assist in her hands in breaking down rocks and strata into soil, nor do they help man to make that soil productive or to collect for him its products.
[The Whig interpretation of history] ... is the tendency in many historians to write on the side of Protestants and Whigs, to praise revolutions provided they have been successful, to emphasise certain principles of progress in the past and to produce a story which is the ratification if not the glorification of the present.
[Recalling Professor Ira Remsen's remarks (1895) to a group of his graduate students about to go out with their degrees into the world beyond the university:]
He talked to us for an hour on what was ahead of us; cautioned us against giving up the desire to push ahead by continued study and work. He warned us against allowing our present accomplishments to be the high spot in our lives. He urged us not to wait for a brilliant idea before beginning independent research, and emphasized the fact the Lavoisier's first contribution to chemistry was the analysis of a sample of gypsum. He told us that the fields in which the great masters had worked were still fruitful; the ground had only been scratched and the gleaner could be sure of ample reward.
He talked to us for an hour on what was ahead of us; cautioned us against giving up the desire to push ahead by continued study and work. He warned us against allowing our present accomplishments to be the high spot in our lives. He urged us not to wait for a brilliant idea before beginning independent research, and emphasized the fact the Lavoisier's first contribution to chemistry was the analysis of a sample of gypsum. He told us that the fields in which the great masters had worked were still fruitful; the ground had only been scratched and the gleaner could be sure of ample reward.
If the Indians hadn’t spent the $24. In 1626 Peter Minuit, first governor of New Netherland, purchased Manhattan Island from the Indians for about $24. … Assume for simplicity a uniform rate of 7% from 1626 to the present, and suppose that the Indians had put their $24 at [compound] interest at that rate …. What would be the amount now, after 280 years? 24 x (1.07)280 = more than 4,042,000,000.
The latest tax assessment available at the time of writing gives the realty for the borough of Manhattan as $3,820,754,181. This is estimated to be 78% of the actual value, making the actual value a little more than $4,898,400,000.
The amount of the Indians’ money would therefore be more than the present assessed valuation but less than the actual valuation.
The latest tax assessment available at the time of writing gives the realty for the borough of Manhattan as $3,820,754,181. This is estimated to be 78% of the actual value, making the actual value a little more than $4,898,400,000.
The amount of the Indians’ money would therefore be more than the present assessed valuation but less than the actual valuation.
Les Leucocytes Et L'esprit De Sacrifice. — Il semble, d'après les recherches de De Bruyne (Phagocytose, 1895) et de ceux qui le citent, que les leucocytes des Lamellibranches — probablement lorsqu'ils ont phagocyté, qu'ils se sont chargés de résidus et de déchets, qu'ils ont, en un mot, accompli leur rôle et bien fait leur devoir — sortent du corps de l'animal et vont mourir dans le milieu ambiant. Ils se sacrifient. Après avoir si bien servi l'organisme par leur activité, ils le servent encore par leur mort en faisant place aux cellules nouvelles, plus jeunes.
N'est-ce pas la parfaite image du désintéressement le plus noble, et n'y a-t-il point là un exemple et un modèle? Il faut s'en inspirer: comme eux, nous sommes les unités d'un grand corps social; comme eux, nous pouvons le servir et envisager la mort avec sérénité, en subordonnant notre conscience individuelle à la conscience collective. (30 Jan 1896)
Leukocytes and The Spirit Of Sacrifice. - It seems, according to research by De Bruyne (Phagocytosis, 1885) and those who quote it, that leukocytes of Lamellibranches [bivalves] - likely when they have phagocytized [ingested bacteria], as they become residues and waste, they have, in short, performed their role well and done their duty - leave the body of the animal and will die in the environment. They sacrifice themselves. Having so well served the body by their activities, they still serve in their death by making room for new younger cells.
Isn't this the perfect image of the noblest selflessness, and thereby presents an example and a model? It should be inspiring: like them, we are the units of a great social body, like them, we can serve and contemplate death with equanimity, subordinating our individual consciousness to collective consciousness.
N'est-ce pas la parfaite image du désintéressement le plus noble, et n'y a-t-il point là un exemple et un modèle? Il faut s'en inspirer: comme eux, nous sommes les unités d'un grand corps social; comme eux, nous pouvons le servir et envisager la mort avec sérénité, en subordonnant notre conscience individuelle à la conscience collective. (30 Jan 1896)
Leukocytes and The Spirit Of Sacrifice. - It seems, according to research by De Bruyne (Phagocytosis, 1885) and those who quote it, that leukocytes of Lamellibranches [bivalves] - likely when they have phagocytized [ingested bacteria], as they become residues and waste, they have, in short, performed their role well and done their duty - leave the body of the animal and will die in the environment. They sacrifice themselves. Having so well served the body by their activities, they still serve in their death by making room for new younger cells.
Isn't this the perfect image of the noblest selflessness, and thereby presents an example and a model? It should be inspiring: like them, we are the units of a great social body, like them, we can serve and contemplate death with equanimity, subordinating our individual consciousness to collective consciousness.
Question: Account for the delicate shades of colour sometimes seen on the inside of an oyster shell. State and explain the appearance presented when a beam of light falls upon a sheet of glass on which very fine equi-distant parallel lines have been scratched very close to one another.
Answer: The delicate shades are due to putrefaction; the colours always show best when the oyster has been a bad one. Hence they are considered a defect and are called chromatic aberration.
The scratches on the glass will arrange themselves in rings round the light, as any one may see at night in a tram car.
Answer: The delicate shades are due to putrefaction; the colours always show best when the oyster has been a bad one. Hence they are considered a defect and are called chromatic aberration.
The scratches on the glass will arrange themselves in rings round the light, as any one may see at night in a tram car.
Qui est de nous & qui seul peut nous égarer; à le mettre continuellement à épreuve de l'expérience; à ne conserver que les faits qui ne font que des données de la nature , & qui ne peuvent nous tromper; à ne chercher la vérité que dans l'enchaînement naturel des expériences & des observations
We must trust to nothing but facts: These are presented to us by Nature, and cannot deceive. We ought, in every instance, to submit our reasoning to the test of experiment, and never to search for truth but by the natural road of experiment and observation.
We must trust to nothing but facts: These are presented to us by Nature, and cannot deceive. We ought, in every instance, to submit our reasoning to the test of experiment, and never to search for truth but by the natural road of experiment and observation.
Surtout l’astronomie et l’anatomie sont les deux sciences qui nous offrent le plus sensiblement deux grands caractères du Créateur; l’une, son immensité, par les distances, la grandeur, et le nombre des corps célestes; l’autre, son intelligence infinie, par la méchanique des animaux.
Above all, astronomy and anatomy are the two sciences which present to our minds most significantly the two grand characteristics of the Creator; the one, His immensity, by the distances, size, and number of the heavenly bodies; the other, His infinite intelligence, by the mechanism of animate beings.
Above all, astronomy and anatomy are the two sciences which present to our minds most significantly the two grand characteristics of the Creator; the one, His immensity, by the distances, size, and number of the heavenly bodies; the other, His infinite intelligence, by the mechanism of animate beings.
Wenn sich für ein neues Fossil kein, auf eigenthümliche Eigenschaften desselben hinweisender, Name auffinden lassen Will; als in welchem Falle ich mich bei dem gegenwärtigen zu befinden gestehe; so halte ich es für besser, eine solche Benennung auszuwählen, die an sich gar nichts sagt, und folglich auch zu keinen unrichtigen Begriffen Anlass geben kann. Diesem zufolge will ich den Namen für die gegenwärtige metallische Substanz, gleichergestalt wie bei dem Uranium geschehen, aus der Mythologie, und zwar von den Ursöhnen der Erde, den Titanen, entlehnen, und benenne also dieses neue Metallgeschlecht: Titanium.
Wherefore no name can be found for a new fossil [element] which indicates its peculiar and characteristic properties (in which position I find myself at present), I think it is best to choose such a denomination as means nothing of itself and thus can give no rise to any erroneous ideas. In consequence of this, as I did in the case of Uranium, I shall borrow the name for this metallic substance from mythology, and in particular from the Titans, the first sons of the earth. I therefore call this metallic genus TITANIUM.
Wherefore no name can be found for a new fossil [element] which indicates its peculiar and characteristic properties (in which position I find myself at present), I think it is best to choose such a denomination as means nothing of itself and thus can give no rise to any erroneous ideas. In consequence of this, as I did in the case of Uranium, I shall borrow the name for this metallic substance from mythology, and in particular from the Titans, the first sons of the earth. I therefore call this metallic genus TITANIUM.
1839—The fermentation satire
THE MYSTERY OF ALCOHOLIC FERMENTATION RESOLVED
(Preliminary Report by Letter) Schwindler
I am about to develop a new theory of wine fermentation … Depending on the weight, these seeds carry fermentation to completion somewhat less than as in the beginning, which is understandable … I shall develop a new theory of wine fermentation [showing] what simple means Nature employs in creating the most amazing phenomena. I owe it to the use of an excellent microscope designed by Pistorius.
When brewer’s yeast is mixed with water the microscope reveals that the yeast dissolves into endless small balls, which are scarcely 1/800th of a line in diameter … If these small balls are placed in sugar water, it can be seen that they consist of the eggs of animals. As they expand, they burst, and from them develop small creatures that multiply with unbelievable rapidity in a most unheard of way. The form of these animals differs from all of the 600 types described up until now. They possess the shape of a Beinsdorff still (without the cooling apparatus). The head of the tube is a sort of proboscis, the inside of which is filled with fine bristles 1/2000th of a line long. Teeth and eyes are not discernible; however, a stomach, intestinal canal, anus (a rose red dot), and organs for secretion of urine are plainly discernible. From the moment they are released from the egg one can see these animals swallow the sugar from the solution and pass it to the stomach. It is digested immediately, a process recognized easily by the resultant evacuation of excrements. In a word, these infusors eat sugar, evacuate ethyl alcohol from the intestinal canal, and carbon dioxide from the urinary organs. The bladder, in the filled state, has the form of a champagne bottle; when empty, it is a small button … As soon as the animals find no more sugar present, they eat each other up, which occurs through a peculiar manipulation; everything is digested down to the eggs which pass unchanged through the intestinal canal. Finally, one again fermentable yeast, namely the seed of the animals, which remain over.
THE MYSTERY OF ALCOHOLIC FERMENTATION RESOLVED
(Preliminary Report by Letter) Schwindler
I am about to develop a new theory of wine fermentation … Depending on the weight, these seeds carry fermentation to completion somewhat less than as in the beginning, which is understandable … I shall develop a new theory of wine fermentation [showing] what simple means Nature employs in creating the most amazing phenomena. I owe it to the use of an excellent microscope designed by Pistorius.
When brewer’s yeast is mixed with water the microscope reveals that the yeast dissolves into endless small balls, which are scarcely 1/800th of a line in diameter … If these small balls are placed in sugar water, it can be seen that they consist of the eggs of animals. As they expand, they burst, and from them develop small creatures that multiply with unbelievable rapidity in a most unheard of way. The form of these animals differs from all of the 600 types described up until now. They possess the shape of a Beinsdorff still (without the cooling apparatus). The head of the tube is a sort of proboscis, the inside of which is filled with fine bristles 1/2000th of a line long. Teeth and eyes are not discernible; however, a stomach, intestinal canal, anus (a rose red dot), and organs for secretion of urine are plainly discernible. From the moment they are released from the egg one can see these animals swallow the sugar from the solution and pass it to the stomach. It is digested immediately, a process recognized easily by the resultant evacuation of excrements. In a word, these infusors eat sugar, evacuate ethyl alcohol from the intestinal canal, and carbon dioxide from the urinary organs. The bladder, in the filled state, has the form of a champagne bottle; when empty, it is a small button … As soon as the animals find no more sugar present, they eat each other up, which occurs through a peculiar manipulation; everything is digested down to the eggs which pass unchanged through the intestinal canal. Finally, one again fermentable yeast, namely the seed of the animals, which remain over.
230(231-1) ... is the greatest perfect number known at present, and probably the greatest that ever will be discovered; for; as they are merely curious without being useful, it is not likely that any person will attempt to find a number beyond it.
A ... hypothesis may be suggested, which supposes the word 'beginning' as applied by Moses in the first of the Book of Genesis, to express an undefined period of time which was antecedent to the last great change that affected the surface of the earth, and to the creation of its present animal and vegetable inhabitants; during which period a long series of operations and revolutions may have been going on, which, as they are wholly unconnected with the history of the human race, are passed over in silence by the sacred historian, whose only concern with them was largely to state, that the matter of the universe is not eternal and self-existent but was originally created by the power of the Almighty.
A drop from the nose of Fleming, who had a cold, fell onto an agar plate where large yellow colonies of a contaminant had grown, and lysosyme was discovered. He made this important discovery because when he saw that the colonies of the contaminant were fading, his mind went straight to the right cause of the phenomenon he was observing—that the drop from his nose contained a lytic substance. And also immediately, he thought that this substance might be present in many secretions and tissues of the body. And he found this was so—the substance was in tears, saliva, leucocytes, skin, fingernails, mother's milk—thus very widely distributed in amounts and also in plants.
A few days ago, a Master of Arts, who is still a young man, and therefore the recipient of a modern education, stated to me that until he had reached the age of twenty he had never been taught anything whatever regarding natural phenomena, or natural law. Twelve years of his life previously had been spent exclusively amongst the ancients. The case, I regret to say, is typical. Now we cannot, without prejudice to humanity, separate the present from the past.
A good many times I have been present at gatherings of people who, by the standards of the traditional culture, are thought highly educated and who have with considerable gusto been expressing their incredulity at the illiteracy of scientists. Once or twice I have been provoked and have asked the company how many of them could describe the Second Law of Thermodynamics. The response was cold: it was also negative. Yet I was asking something which is about the scientific equivalent of: Have you read a work of Shakespeare’s?
A good physiological experiment like a good physical one requires that it should present anywhere, at any time, under identical conditions, the same certain and unequivocal phenomena that can always be confirmed.
A great book is a mine as well as a mint: it suggests and excites as much thought as it presents in finished form.
A great department of thought must have its own inner life, however transcendent may be the importance of its relations to the outside. No department of science, least of all one requiring so high a degree of mental concentration as Mathematics, can be developed entirely, or even mainly, with a view to applications outside its own range. The increased complexity and specialisation of all branches of knowledge makes it true in the present, however it may have been in former times, that important advances in such a department as Mathematics can be expected only from men who are interested in the subject for its own sake, and who, whilst keeping an open mind for suggestions from outside, allow their thought to range freely in those lines of advance which are indicated by the present state of their subject, untrammelled by any preoccupation as to applications to other departments of science. Even with a view to applications, if Mathematics is to be adequately equipped for the purpose of coping with the intricate problems which will be presented to it in the future by Physics, Chemistry and other branches of physical science, many of these problems probably of a character which we cannot at present forecast, it is essential that Mathematics should be allowed to develop freely on its own lines.
A great reform in geological speculation seems now to have become necessary. … It is quite certain that a great mistake has been made—that British popular geology at the present time is in direct opposition to the principles of Natural Philosophy.
A happy man is too satisfied with the present to dwell too much on the future.
A hundred years ago the study of life was often pursued, and also presented to the public, in a highly unified way. Darwin, as everyone knows, in addressing the world at large began his story with the history of pigeons and ended it with the breeding of primroses, having made excursions on the way into the origins of coral reefs and of the races of Man.
A manure containing several ingredients acts in this wise: The effect of all of them in the soil accommodates itself to that one among them which, in comparison to the wants of the plant, is present in the smallest quantity.
A mathematical point is the most indivisble and unique thing which art can present.
A moment’s consideration of this case shows what a really great advance in the theory and practise of breeding has been obtained through the discovery of Mendel’s law. What a puzzle this case would have presented to the biologist ten years ago! Agouti crossed with chocolate gives in the second filial generation (not in the first) four varieties, viz., agouti, chocolate, black and cinnamon. We could only have shaken our heads and looked wise (or skeptical).
Then we had no explanation to offer for such occurrences other than the “instability of color characters under domestication,” the “effects of inbreeding,” “maternal impressions.” Serious consideration would have been given to the proximity of cages containing both black and cinnamon-agouti mice.
Now we have a simple, rational explanation, which anyone can put to the test. We are able to predict the production of new varieties, and to produce them.
We must not, of course, in our exuberance, conclude that the powers of the hybridizer know no limits. The result under consideration consists, after all, only in the making of new combinations of unit characters, but it is much to know that these units exist and that all conceivable combinations of them are ordinarily capable of production. This valuable knowledge we owe to the discoverer and to the rediscoverers of Mendel’s law.
Then we had no explanation to offer for such occurrences other than the “instability of color characters under domestication,” the “effects of inbreeding,” “maternal impressions.” Serious consideration would have been given to the proximity of cages containing both black and cinnamon-agouti mice.
Now we have a simple, rational explanation, which anyone can put to the test. We are able to predict the production of new varieties, and to produce them.
We must not, of course, in our exuberance, conclude that the powers of the hybridizer know no limits. The result under consideration consists, after all, only in the making of new combinations of unit characters, but it is much to know that these units exist and that all conceivable combinations of them are ordinarily capable of production. This valuable knowledge we owe to the discoverer and to the rediscoverers of Mendel’s law.
A time will come, when fields will be manured with a solution of glass (silicate of potash), with the ashes of burnt straw, and with the salts of phosphoric acid, prepared in chemical manufactories, exactly as at present medicines are given for fever and goitre.
About eight days ago I discovered that sulfur in burning, far from losing weight, on the contrary, gains it; it is the same with phosphorus; this increase of weight arises from a prodigious quantity of air that is fixed during combustion and combines with the vapors. This discovery, which I have established by experiments, that I regard as decisive, has led me to think that what is observed in the combustion of sulfur and phosphorus may well take place in the case of all substances that gain in weight by combustion and calcination; and I am persuaded that the increase in weight of metallic calxes is due to the same cause... This discovery seems to me one of the most interesting that has been made since Stahl and since it is difficult not to disclose something inadvertently in conversation with friends that could lead to the truth I have thought it necessary to make the present deposit to the Secretary of the Academy to await the time I make my experiments public.
Access to more information isn’t enough—the information needs to be correct, timely, and presented in a manner that enables the reader to learn from it. The current network is full of inaccurate, misleading, and biased information that often crowds out the valid information. People have not learned that “popular” or “available” information is not necessarily valid.
Active experimentation must force the apparent facts of nature into forms different to those in which they familiarly present themselves; and thus make them tell the truth about themselves, as torture may compel an unwilling witness to reveal what he has been concealing.
After five years' work I allowed myself to speculate on the subject, and drew up some short notes; these I enlarged in 1844 into a sketch of the conclusions, which then seemed to me probable: from that period to the present day I have steadily pursued the same object. I hope that I may be excused for entering on these personal details, as I give them to show that I have not been hasty in coming to a decision.
All fossil anthropoids found hitherto have been known only from mandibular or maxillary fragments, so far as crania are concerned, and so the general appearance of the types they represented had been unknown; consequently, a condition of affairs where virtually the whole face and lower jaw, replete with teeth, together with the major portion of the brain pattern, have been preserved, constitutes a specimen of unusual value in fossil anthropoid discovery. Here, as in Homo rhodesiensis, Southern Africa has provided documents of higher primate evolution that are amongst the most complete extant. Apart from this evidential completeness, the specimen is of importance because it exhibits an extinct race of apes intermediate between living anthropoids and man ... Whether our present fossil is to be correlated with the discoveries made in India is not yet apparent; that question can only be solved by a careful comparison of the permanent molar teeth from both localities. It is obvious, meanwhile, that it represents a fossil group distinctly advanced beyond living anthropoids in those two dominantly human characters of facial and dental recession on one hand, and improved quality of the brain on the other. Unlike Pithecanthropus, it does not represent an ape-like man, a caricature of precocious hominid failure, but a creature well advanced beyond modern anthropoids in just those characters, facial and cerebral, which are to be anticipated in an extinct link between man and his simian ancestor. At the same time, it is equally evident that a creature with anthropoid brain capacity and lacking the distinctive, localised temporal expansions which appear to be concomitant with and necessary to articulate man, is no true man. It is therefore logically regarded as a man-like ape. I propose tentatively, then, that a new family of Homo-simidæ be created for the reception of the group of individuals which it represents, and that the first known species of the group be designated Australopithecus africanus, in commemoration, first, of the extreme southern and unexpected horizon of its discovery, and secondly, of the continent in which so many new and important discoveries connected with the early history of man have recently been made, thus vindicating the Darwinian claim that Africa would prove to be the cradle of mankind.
All good intellects have repeated, since Bacon’s time, that there can be no real knowledge but that which is based on observed facts. This is incontestable, in our present advanced stage; but, if we look back to the primitive stage of human knowledge, we shall see that it must have been otherwise then. If it is true that every theory must be based upon observed facts, it is equally true that facts cannot be observed without the guidance of some theory. Without such guidance, our facts would be desultory and fruitless; we could not retain them: for the most part we could not even perceive them.
All palaetiological sciences, all speculations which attempt to ascend from the present to the remote past, by the chain of causation, do also, by an inevitable consequence, urge us to look for the beginning of the state of things which we thus contemplate; but in none of these cases have men been able, by the aid of science, to arrive at a beginning which is homogeneous with the known course of events. The first origin of language, of civilization, of law and government, cannot be clearly made out by reasoning and research; and just as little, we may expect, will a knowledge of the origin of the existing and extinct species of plants and animals, be the result of physiological and geological investigation.
All that concerns the Mediterranean is of the deepest interest to civilized man, for the history of its progress is the history of the development of the world; the memory of the great men who have lived and died around its banks; the recollection of the undying works that have come thence to delight us for ever; the story of patient research and brilliant discoveries connected with every physical phenomenon presented by its waves and currents, and with every order of creatures dwelling in and around its waters.
All the modern higher mathematics is based on a calculus of operations, on laws of thought. All mathematics, from the first, was so in reality; but the evolvers of the modern higher calculus have known that it is so. Therefore elementary teachers who, at the present day, persist in thinking about algebra and arithmetic as dealing with laws of number, and about geometry as dealing with laws of surface and solid content, are doing the best that in them lies to put their pupils on the wrong track for reaching in the future any true understanding of the higher algebras. Algebras deal not with laws of number, but with such laws of the human thinking machinery as have been discovered in the course of investigations on numbers. Plane geometry deals with such laws of thought as were discovered by men intent on finding out how to measure surface; and solid geometry with such additional laws of thought as were discovered when men began to extend geometry into three dimensions.
Almost every major systematic error which has deluded men for thousands of years relied on practical experience. Horoscopes, incantations, oracles, magic, witchcraft, the cures of witch doctors and of medical practitioners before the advent of modern medicine, were all firmly established through the centuries in the eyes of the public by their supposed practical successes. The scientific method was devised precisely for the purpose of elucidating the nature of things under more carefully controlled conditions and by more rigorous criteria than are present in the situations created by practical problems.
Although the cooking of food presents some unsolved problems, the quick warming of cooked food and the thawing of frozen food both open up some attractive uses. ... There is no important reason why the the housewife of the future should not purchase completely frozen meals at the grocery store just as she buys quick frozen vegetables. With a quick heating, high-frequency unit in her kitchen, food preparation from a pre-cooked, frozen meal becomes a simple matter.
[Predicting home kitchen appliances could be developed from the radionic tube employed to jam enemy radar in World War II.]
[Predicting home kitchen appliances could be developed from the radionic tube employed to jam enemy radar in World War II.]
Although with the majority of those who study and practice in these capacities [engineers, builders, surveyors, geographers, navigators, hydrographers, astronomers], secondhand acquirements, trite formulas, and appropriate tables are sufficient for ordinary purposes, yet these trite formulas and familiar rules were originally or gradually deduced from the profound investigations of the most gifted minds, from the dawn of science to the present day. … The further developments of the science, with its possible applications to larger purposes of human utility and grander theoretical generalizations, is an achievement reserved for a few of the choicest spirits, touched from time to time by Heaven to these highest issues. The intellectual world is filled with latent and undiscovered truth as the material world is filled with latent electricity.
Among all the occurrences possible in the universe the a priori probability of any particular one of them verges upon zero. Yet the universe exists; particular events must take place in it, the probability of which (before the event) was infinitesimal. At the present time we have no legitimate grounds for either asserting or denying that life got off to but a single start on earth, and that, as a consequence, before it appeared its chances of occurring were next to nil. ... Destiny is written concurrently with the event, not prior to it.
An archaeologist is a scientist who seeks to discover past civilizations while the present one is still around.
An extraterrestrial being, newly arrived on Earth - scrutinizing what we mainly present to our children in television, radio, movies, newspapers, magazines, the comics, and many books - might easily conclude that we are intent on teaching them murder, rape, cruelty, superstition, credulity and consumerism.
An ignorant or half-informed teacher may present science as an accumulation of unconnected facts. … To teach in that fashion is like going to the tree of science with its glorious fruit in order to pick up a handful of the dry fallen leaves from the ground.
An immune system of enormous complexity is present in all vertebrate animals. When we place a population of lymphocytes from such an animal in appropriate tissue culture fluid, and when we add an antigen, the lymphocytes will produce specific antibody molecules, in the absence of any nerve cells. I find it astonishing that the immune system embodies a degree of complexity which suggests some more or less superficial though striking analogies with human language, and that this cognitive system has evolved and functions without assistance of the brain.
An unelectrified atom is so elusive that unless more than a million million are present we have no means sufficiently sensitive to detect them, or, to put it another way, unless we had a better test for a man than for an unelectrified molecule, we should be unable to find out that the earth was inhabited. … A billion unelectrified atoms may escape our observation, whereas a dozen or so electrified ones are detected without difficulty.
And from true lordship it follows that the true God is living, intelligent, and powerful; from the other perfections, that he is supreme, or supremely perfect. He is eternal and infinite, omnipotent and omniscient; that is, he endures from eternity to eternity; and he is present from infinity to infinity; he rules all things, and he knows all things that happen or can happen.
And if you want the exact moment in time, it was conceived mentally on 8th March in this year one thousand six hundred and eighteen, but submitted to calculation in an unlucky way, and therefore rejected as false, and finally returning on the 15th of May and adopting a new line of attack, stormed the darkness of my mind. So strong was the support from the combination of my labour of seventeen years on the observations of Brahe and the present study, which conspired together, that at first I believed I was dreaming, and assuming my conclusion among my basic premises. But it is absolutely certain and exact that the proportion between the periodic times of any two planets is precisely the sesquialterate proportion of their mean distances.
Anyone who has had actual contact with the making of the inventions that built the radio art knows that these inventions have been the product of experiment and work based on physical reasoning, rather than on the mathematicians' calculations and formulae. Precisely the opposite impression is obtained from many of our present day text books and publications.
As a progressive discipline [biochemistry] belongs to the present century. From the experimental physiologists of the last century it obtained a charter, and, from a few pioneers of its own, a promise of success; but for the furtherance of its essential aim that century left it but a small inheritance of facts and methods. By its essential or ultimate aim I myself mean an adequate and acceptable description of molecular dynamics in living cells and tissues.
As every circumstance relating to so capital a discovery as this (the greatest, perhaps, that has been made in the whole compass of philosophy, since the time of Sir Isaac Newton) cannot but give pleasure to all my readers, I shall endeavour to gratify them with the communication of a few particulars which I have from the best authority. The Doctor [Benjamin Franklin], after having published his method of verifying his hypothesis concerning the sameness of electricity with the matter lightning, was waiting for the erection of a spire in Philadelphia to carry his views into execution; not imagining that a pointed rod, of a moderate height, could answer the purpose; when it occurred to him, that, by means of a common kite, he could have a readier and better access to the regions of thunder than by any spire whatever. Preparing, therefore, a large silk handkerchief, and two cross sticks, of a proper length, on which to extend it, he took the opportunity of the first approaching thunder storm to take a walk into a field, in which there was a shed convenient for his purpose. But dreading the ridicule which too commonly attends unsuccessful attempts in science, he communicated his intended experiment to no body but his son, who assisted him in raising the kite.
The kite being raised, a considerable time elapsed before there was any appearance of its being electrified. One very promising cloud passed over it without any effect; when, at length, just as he was beginning to despair of his contrivance, he observed some loose threads of the hempen string to stand erect, and to avoid one another, just as if they had been suspended on a common conductor. Struck with this promising appearance, he inmmediately presented his knuckle to the key, and (let the reader judge of the exquisite pleasure he must have felt at that moment) the discovery was complete. He perceived a very evident electric spark. Others succeeded, even before the string was wet, so as to put the matter past all dispute, and when the rain had wetted the string, he collected electric fire very copiously. This happened in June 1752, a month after the electricians in France had verified the same theory, but before he had heard of any thing that they had done.
The kite being raised, a considerable time elapsed before there was any appearance of its being electrified. One very promising cloud passed over it without any effect; when, at length, just as he was beginning to despair of his contrivance, he observed some loose threads of the hempen string to stand erect, and to avoid one another, just as if they had been suspended on a common conductor. Struck with this promising appearance, he inmmediately presented his knuckle to the key, and (let the reader judge of the exquisite pleasure he must have felt at that moment) the discovery was complete. He perceived a very evident electric spark. Others succeeded, even before the string was wet, so as to put the matter past all dispute, and when the rain had wetted the string, he collected electric fire very copiously. This happened in June 1752, a month after the electricians in France had verified the same theory, but before he had heard of any thing that they had done.
As geologists, we learn that it is not only the present condition of the globe that has been suited to the accommodation of myriads of living creatures, but that many former states also have been equally adapted to the organization and habits of prior races of beings. The disposition of the seas, continents, and islands, and the climates have varied; so it appears that the species have been changed, and yet they have all been so modelled, on types analogous to those of existing plants and animals, as to indicate throughout a perfect harmony of design and unity of purpose. To assume that the evidence of the beginning or end of so vast a scheme lies within the reach of our philosophical inquiries, or even of our speculations, appears to us inconsistent with a just estimate of the relations which subsist between the finite powers of man and the attributes of an Infinite and Eternal Being.
As historians, we refuse to allow ourselves these vain speculations which turn on possibilities that, in order to be reduced to actuality, suppose an overturning of the Universe, in which our globe, like a speck of abandoned matter, escapes our vision and is no longer an object worthy of our regard. In order to fix our vision, it is necessary to take it such as it is, to observe well all parts of it, and by indications infer from the present to the past.
As I strayed into the study of an eminent physicist, I observed hanging against the wall, framed like a choice engraving, several dingy, ribbon-like strips of, I knew not what... My curiosity was at once aroused. What were they? ... They might be shreds of mummy-wraps or bits of friable bark-cloth from the Pacific, ... [or] remnants from a grandmother’s wedding dress... They were none of these... He explained that they were carefully-prepared photographs of portions of the Solar Spectrum. I stood and mused, absorbed in the varying yet significant intensities of light and shade, bordered by mystic letters and symbolic numbers. As I mused, the pale legend began to glow with life. Every line became luminous with meaning. Every shadow was suffused with light shining from behind, suggesting some mighty achievement of knowledge; of knowledge growing more daring in proportion to the remoteness of the object known; of knowledge becoming more positive in its answers, as the questions which were asked seemed unanswerable. No Runic legend, no Babylonish arrowhead, no Egyptian hieroglyph, no Moabite stone, could present a history like this, or suggest thoughts of such weighty import or so stimulate and exalt the imagination.
As there is not in human observation proper means for measuring the waste of land upon the globe, it is hence inferred, that we cannot estimate the duration of what we see at present, nor calculate the period at which it had begun; so that, with respect to human observation, this world has neither a beginning nor an end.
As to Science, she has never sought to ally herself to civil power. She has never attempted to throw odium or inflict social ruin on any human being. She has never subjected anyone to mental torment, physical torture, least of all to death, for the purpose of upholding or promoting her ideas. She presents herself unstained by cruelties and crimes. But in the Vatican—we have only to recall the Inquisition—the hands that are now raised in appeals to the Most Merciful are crimsoned. They have been steeped in blood!
Astronomy, as the science of cyclical motions, has nothing in common with Geology. But look at Astronomy where she has an analogy with Geology; consider our knowledge of the heavens as a palaetiological science;—as the study of a past condition, from which the present is derived by causes acting in time. Is there no evidence of a beginning, or of a progress?
At any given instant
All solids dissolve, no wheels revolve,
And facts have no endurance—
And who knows if it is by design or pure inadvertence
That the Present destroys its inherited self-importance?
All solids dissolve, no wheels revolve,
And facts have no endurance—
And who knows if it is by design or pure inadvertence
That the Present destroys its inherited self-importance?
At every major step physics has required, and frequently stimulated, the introduction of new mathematical tools and concepts. Our present understanding of the laws of physics, with their extreme precision and universality, is only possible in mathematical terms.
At present good work in science pays less well very often than mediocrity in other subjects. This, as was pointed out by Sir Lyon Playfair in his Presidential Address to the British Association in 1885 helps to arrest progress in science teaching.
At present we begin to feel impatient, and to wish for a new state of chemical elements. For a time the desire was to add to the metals, now we wish to diminish their number. They increase upon us continually, and threaten to enclose within their ranks the bounds of our fair fields of chemical science. The rocks of the mountain and the soil of the plain, the sands of the sea and the salts that are in it, have given way to the powers we have been able to apply to them, but only to be replaced by metals.
At present we must confine ourselves to saying that soul is the source of these phenomena and is characterized by them, viz. by the powers of self-nutrition, sensation, thinking, and movement.
At that point, my sense of dissatisfaction was so strong that I firmly resolved to start thinking until I should find a purely arithmetic and absolutely rigorous foundation of the principles of infinitesimal analysis. … I achieved this goal on November 24th, 1858, … but I could not really decide upon a proper publication, because, firstly, the subject is not easy to present, and, secondly, the material is not very fruitful.
At the present rate of progress, it is almost impossible to imagine any technical feat that cannot be achieved, if it can be achieved at all, within the next five hundred years.
At the present time all property is personal; the man owns his own ponies and other belongings he has personally acquired; the woman owns her horses, dogs, and all the lodge equipments; children own their own articles; and parents do not control the possessions of their children. There is no family property as we use the term. A wife is as independent as the most independent man in our midst. If she chooses to give away or sell all of her property, there is no one to gainsay her.
At the present time it is of course quite customary for physicists to trespass on chemical ground, for mathematicians to do excellent work in physics, and for physicists to develop new mathematical procedures. … Trespassing is one of the most successful techniques in science.
At the present time the fishing industry is, in some ways, at the stage at which primitive man was many centuries ago—we hunt the fish that Nature provides, just as our ancestors hunted animals for food. We have not yet begun to herd fish or to improve their quality—but one day we shall be forced to farm the seas as we do the land.
At the present time there exist problems beyond our ability to solve, not because of theoretical difficulties, but because of insufficient means of mechanical computation.
Because science flourishes, must poesy decline? The complaint serves but to betray the weakness of the class who urge it. True, in an age like the present,—considerably more scientific than poetical,—science substitutes for the smaller poetry of fiction, the great poetry of truth.
But here it may be objected, that the present Earth looks like a heap of Rubbish and Ruines; And that there are no greater examples of confusion in Nature than Mountains singly or jointly considered; and that there appear not the least footsteps of any Art or Counsel either in the Figure and Shape, or Order and Disposition of Mountains and Rocks. Wherefore it is not likely they came so out of God's hands ... To which I answer, That the present face of the Earth with all its Mountains and Hills, its Promontaries and Rocks, as rude and deformed as they appear, seems to me a very beautiful and pleasant object, and with all the variety of Hills, and Valleys, and Inequalities far more grateful to behold, than a perfectly level Countrey without any rising or protuberancy, to terminate the sight: As anyone that hath but seen the Isle of Ely, or any the like Countrey must need acknowledge.
— John Ray
But I think that in the repeated and almost entire changes of organic types in the successive formations of the earth—in the absence of mammalia in the older, and their very rare appearance (and then in forms entirely. unknown to us) in the newer secondary groups—in the diffusion of warm-blooded quadrupeds (frequently of unknown genera) through the older tertiary systems—in their great abundance (and frequently of known genera) in the upper portions of the same series—and, lastly, in the recent appearance of man on the surface of the earth (now universally admitted—in one word, from all these facts combined, we have a series of proofs the most emphatic and convincing,—that the existing order of nature is not the last of an uninterrupted succession of mere physical events derived from laws now in daily operation: but on the contrary, that the approach to the present system of things has been gradual, and that there has been a progressive development of organic structure subservient to the purposes of life.
But if we are to control evolution we shall have to find out how to influence gene reproduction in a definite direction, just as organic chemists nowadays work for definite ends. Such a possibility is at present entirely beyond our grasp, but a century hence it may not be so.
But in its [the corpuscular theory of radiation] relation to the wave theory there is one extraordinary and, at present, insoluble problem. It is not known how the energy of the electron in the X-ray bulb is transferred by a wave motion to an electron in the photographic plate or in any other substance on which the X-rays fall. It is as if one dropped a plank into the sea from the height of 100 ft. and found that the spreading ripple was able, after travelling 1000 miles and becoming infinitesimal in comparison with its original amount, to act upon a wooden ship in such a way that a plank of that ship flew out of its place to a height of 100 ft. How does the energy get from one place to the other?
But in the present century, thanks in good part to the influence of Hilbert, we have come to see that the unproved postulates with which we start are purely arbitrary. They must be consistent, they had better lead to something interesting.
But of all environments, that produced by man’s complex technology is perhaps the most unstable and rickety. In its present form, our society is not two centuries old, and a few nuclear bombs will do it in.
To be sure, evolution works over long periods of time and two centuries is far from sufficient to breed Homo technikos… .
The destruction of our technological society in a fit of nuclear peevishness would become disastrous even if there were many millions of immediate survivors.
The environment toward which they were fitted would be gone, and Darwin’s demon would wipe them out remorselessly and without a backward glance.
To be sure, evolution works over long periods of time and two centuries is far from sufficient to breed Homo technikos… .
The destruction of our technological society in a fit of nuclear peevishness would become disastrous even if there were many millions of immediate survivors.
The environment toward which they were fitted would be gone, and Darwin’s demon would wipe them out remorselessly and without a backward glance.
But the fact is that when wine is taken in moderation, it gives rise to a large amount of breath, whose character is balanced, and whose luminosity is strong and brilliant. Hence wine disposes greatly to gladness, and the person is subject to quite trivial exciting agents. The breath now takes up the impression of agents belonging to the present time more easily than it does those which relate to the future; it responds to agents conducive to delight rather than those conducive to a sense of beauty.
— Avicenna
But the idea of science and systematic knowledge is wanting to our whole instruction alike, and not only to that of our business class ... In nothing do England and the Continent at the present moment more strikingly differ than in the prominence which is now given to the idea of science there, and the neglect in which this idea still lies here; a neglect so great that we hardly even know the use of the word science in its strict sense, and only employ it in a secondary and incorrect sense.
But the Presidence of that mighty Power … its particular Agency and Concern therein: and its Purpose and Design … will more evidently appear, when I shall have proved … That the said Earth, though not indifferently and alike fertil in all parts of it, was yet generally much more fertil than ours is … That its Soil was more luxuriant, and teemed forth its Productions in far greater plenty and abundance than the present Earth does … That when Man was fallen, and had abandoned his primitive Innocence, the Case was much altered: and a far different Scene of Things presented; that generous Vertue, masculine Bravery, and prudent Circumspection which he was before Master of, now deserting him … and a strange imbecility immediately seized and laid hold of him: he became pusillanimous, and was easily ruffled with every little Passion within: supine, and as openly exposed to any Temptation or Assault from without. And now these exuberant Productions of the Earth became a continued Decoy and Snare unto him.
By considering the embryological structure of man - the homologies which he presents with the lower animals - the rudiments which he retains - and the reversions to which he is liable, we can partly recall in imagination the former condition of our early progenitors; and we can approximately place them in their proper position in the zoological series. We thus learnt that man is descended from a hairy quadruped, furnished with a tail and pointed ears, probably arboreal in its habit, and an inhabitant of the Old World. This creature, if its whole structure had been examined by a naturalist, would have been classed among the Quadrumana, as surely as would be the common and still more ancient progenitor of the Old and New World monkeys.
By destroying the biological character of phenomena, the use of averages in physiology and medicine usually gives only apparent accuracy to the results. From our point of view, we may distinguish between several kinds of averages: physical averages, chemical averages and physiological and pathological averages. If, for instance, we observe the number of pulsations and the degree of blood pressure by means of the oscillations of a manometer throughout one day, and if we take the average of all our figures to get the true or average blood pressure and to learn the true or average number of pulsations, we shall simply have wrong numbers. In fact, the pulse decreases in number and intensity when we are fasting and increases during digestion or under different influences of movement and rest; all the biological characteristics of the phenomenon disappear in the average. Chemical averages are also often used. If we collect a man's urine during twenty-four hours and mix all this urine to analyze the average, we get an analysis of a urine which simply does not exist; for urine, when fasting, is different from urine during digestion. A startling instance of this kind was invented by a physiologist who took urine from a railroad station urinal where people of all nations passed, and who believed he could thus present an analysis of average European urine! Aside from physical and chemical, there are physiological averages, or what we might call average descriptions of phenomena, which are even more false. Let me assume that a physician collects a great many individual observations of a disease and that he makes an average description of symptoms observed in the individual cases; he will thus have a description that will never be matched in nature. So in physiology, we must never make average descriptions of experiments, because the true relations of phenomena disappear in the average; when dealing with complex and variable experiments, we must study their various circumstances, and then present our most perfect experiment as a type, which, however, still stands for true facts. In the cases just considered, averages must therefore be rejected, because they confuse, while aiming to unify, and distort while aiming to simplify. Averages are applicable only to reducing very slightly varying numerical data about clearly defined and absolutely simple cases.
Cauchy is mad, and there is no way of being on good terms with him, although at present he is the only man who knows how mathematics should be treated. What he does is excellent, but very confused…
Change is the law of life. And those who look only to the past or the present are certain to miss the future.
Clarity about the aims and problems of socialism is of greatest significance in our age of transition. Since, under present circumstances, free and unhindered discussion of these problems has come under a powerful taboo, I consider the foundation of this magazine to be an important public service.
Combining in our survey then, the whole range of deposits from the most recent to the most ancient group, how striking a succession do they present:– so various yet so uniform–so vast yet so connected. In thus tracing back to the most remote periods in the physical history of our continents, one system of operations, as the means by which many complex formations have been successively produced, the mind becomes impressed with the singleness of nature's laws; and in this respect, at least, geology is hardly inferior in simplicity to astronomy.
Commitment to the Space Shuttle program is the right step for America to take, in moving out from our present beach-head in the sky to achieve a real working presence in space—because the Space Shuttle will give us routine access to space by sharply reducing costs in dollars and preparation time.
Consciousness… does not appear to itself chopped up in bits. Such words as “chain” or “train” do not describe it fitly as it presents itself in the first instance. It is nothing jointed; it flows. A “river” or a “stream” are the metaphors by which it is most naturally described. In talking of it hereafter, let us call it the stream of thought, of consciousness, or of subjective life.
Source of the expression “stream of consciousness”.
Source of the expression “stream of consciousness”.
Conservation and rural-life policies are really two sides of the same policy; and down at the bottom this policy rests upon the fundamental law that neither man nor nation can prosper unless, in dealing with the present, thought is steadily given for the future.
Considerable obstacles generally present themselves to the beginner, in studying the elements of Solid Geometry, from the practice which has hitherto uniformly prevailed in this country, of never submitting to the eye of the student, the figures on whose properties he is reasoning, but of drawing perspective representations of them upon a plane. ...I hope that I shall never be obliged to have recourse to a perspective drawing of any figure whose parts are not in the same plane.
Cosmology is a science which has only a few observable facts to work with. The discovery of the cosmic microwave background radiation added one—the present radiation temperature of the universe. This, however, was a significant increase in our knowledge since it requires a cosmology with a source for the radiation at an early epoch and is a new probe of that epoch. More sensitive measurements of the background radiation in the future will allow us to discover additional facts about the universe.
Could the waters of the Atlantic be drawn off so as to expose to view this great seagash which separates continents, and extends from the Arctic to the Antarctic, it would present a scene the most rugged, grand and imposing. The very ribs of the solid earth, with the foundations of the sea, would be brought to light.
Curves that have no tangents are the rule. … Those who hear of curves without tangents, or of functions without derivatives, often think at first that Nature presents no such complications. … The contrary however is true. … Consider, for instance, one of the white flakes that are obtained by salting a solution of soap. At a distance its contour may appear sharply defined, but as we draw nearer its sharpness disappears. The eye can no longer draw a tangent at any point. … The use of a magnifying glass or microscope leaves us just as uncertain, for fresh irregularities appear every time we increase the magnification. … An essential characteristic of our flake … is that we suspect … that any scale involves details that absolutely prohibit the fixing of a tangent.
Daniel Bernoulli used to tell two little adventures, which he said had given him more pleasure than all the other honours he had received. Travelling with a learned stranger, who, being pleased with his conversation, asked his name; “I am Daniel Bernoulli,” answered he with great modesty; “and I,” said the stranger (who thought he meant to laugh at him) “am Isaac Newton.” Another time, having to dine with the celebrated Koenig, the mathematician, who boasted, with some degree of self-complacency, of a difficult problem he had solved with much trouble, Bernoulli went on doing the honours of his table, and when they went to drink coffee he presented Koenig with a solution of the problem more elegant than his own.
Defenders of the short-sighted men who in their greed and selfishness will, if permitted, rob our country of half its charm by their reckless extermination of all useful and beautiful wild things sometimes seek to champion them by saying the “the game belongs to the people.” So it does; and not merely to the people now alive, but to the unborn people. The “greatest good for the greatest number” applies to the number within the womb of time, compared to which those now alive form but an insignificant fraction. Our duty to the whole, including the unborn generations, bids us restrain an unprincipled present-day minority from wasting the heritage of these unborn generations. The movement for the conservation of wild life and the larger movement for the conservation of all our natural resources are essentially democratic in spirit, purpose, and method.
Descartes is the completest type which history presents of the purely mathematical type of mind—that in which the tendencies produced by mathematical cultivation reign unbalanced and supreme.
Dr. Walter Baade of Mount Wilson Observatory facetiously accused the present generation of Milky Way astronomers of not having looked sufficiently far beyond our “local swimming hole”.
During a conversation with the writer in the last weeks of his life, Sylvester remarked as curious that notwithstanding he had always considered the bent of his mind to be rather analytical than geometrical, he found in nearly every case that the solution of an analytical problem turned upon some quite simple geometrical notion, and that he was never satisfied until he could present the argument in geometrical language.
During the first half of the present century we had an Alexander von Humboldt, who was able to scan the scientific knowledge of his time in its details, and to bring it within one vast generalization. At the present juncture, it is obviously very doubtful whether this task could be accomplished in a similar way, even by a mind with gifts so peculiarly suited for the purpose as Humboldt's was, and if all his time and work were devoted to the purpose.
Electric and magnetic forces. May they live for ever, and never be forgot, if only to remind us that the science of electromagnetics, in spite of the abstract nature of its theory, involving quantities whose nature is entirely unknown at the present, is really and truly founded on the observations of real Newtonian forces, electric and magnetic respectively.
Endowed with two qualities, which seemed incompatible with each other, a volcanic imagination and a pertinacity of intellect which the most tedious numerical calculations could not daunt, Kepler conjectured that the movements of the celestial bodies must be connected together by simple laws, or, to use his own expression, by harmonic laws. These laws he undertook to discover. A thousand fruitless attempts, errors of calculation inseparable from a colossal undertaking, did not prevent him a single instant from advancing resolutely toward the goal of which he imagined he had obtained a glimpse. Twenty-two years were employed by him in this investigation, and still he was not weary of it! What, in reality, are twenty-two years of labor to him who is about to become the legislator of worlds; who shall inscribe his name in ineffaceable characters upon the frontispiece of an immortal code; who shall be able to exclaim in dithyrambic language, and without incurring the reproach of anyone, “The die is cast; I have written my book; it will be read either in the present age or by posterity, it matters not which; it may well await a reader, since God has waited six thousand years for an interpreter of his words.”
Entrepreneurs must devote a portion of their minds to constantly processing uncertainty. So you sacrifice a degree of being present.
Equations are more important to me, because politics is for the present, but an equation is something for eternity.
Equations seem like treasures, spotted in the rough by some discerning individual, plucked and examined, placed in the grand storehouse of knowledge, passed on from generation to generation. This is so convenient a way to present scientific discovery, and so useful for textbooks, that it can be called the treasure-hunt picture of knowledge.
Ere long intelligence—transmitted without wires—will throb through the earth like a pulse through a living organism. The wonder is that, with the present state of knowledge and the experiences gained, no attempt is being made to disturb the electrostatic or magnetic condition of the earth, and transmit, if nothing else, intelligence.
Etna presents us not merely with an image of the power of subterranean heat, but a record also of the vast period of time during which that power has been exerted. A majestic mountain has been produced by volcanic action, yet the time of which the volcanic forms the register, however vast, is found by the geologist to be of inconsiderable amount, even in the modern annals of the earth’s history. In like manner, the Falls of Niagara teach us not merely to appreciate the power of moving water, but furnish us at the same time with data for estimating the enormous lapse of ages during which that force has operated. A deep and long ravine has been excavated, and the river has required ages to accomplish the task, yet the same region affords evidence that the sum of these ages is as nothing, and as the work of yesterday, when compared to the antecedent periods, of which there are monuments in the same district.
Even more difficult to explain, than the breaking-up of a single mass into fragments, and the drifting apart of these blocks to form the foundations of the present-day continents, is the explanation of the original production of the single mass, or PANGAEA, by the concentration of the former holosphere of granitic sial into a hemisphere of compressed and crushed gneisses and schists. Creep and the effects of compression, due to shrinking or other causes, have been appealed to but this is hardly a satisfactory explanation. The earth could no more shrug itself out of its outer rock-shell unaided, than an animal could shrug itself out of its hide, or a man wriggle out of his skin, or even out of his closely buttoned coat, without assistance either of his own hands or those of others.
Every time you tear a leaf off a calendar, you present a new place for new ideas and progress.
Every variety of philosophical and theological opinion was represented there [The Metaphysical Society], and expressed itself with entire openness; most of my colleagues were -ists of one sort or another; and, however kind and friendly they might be, I, the man without a rag of a label to cover himself with, could not fail to have some of the uneasy feelings which must have beset the historical fox when, after leaving the trap in which his tail remained, he presented himself to his normally elongated companions. So I took thought, and invented what I conceived to be the appropriate title of “agnostic” .
Every writer must reconcile, as best he may, the conflicting claims of consistency and variety, of rigour in detail and elegance in the whole. The present author humbly confesses that, to him, geometry is nothing at all, if not a branch of art.
Everything that the human race has done and thought is concerned with the satisfaction of deeply felt needs and the assuagement of pain. One has to keep this constantly in mind if one wishes to understand spiritual movements and their development. Feeling and longing are the motive force behind all human endeavor and human creation, in however exalted a guise the latter may present themselves to us.
Faraday thinks from day to day, against a background of older thinking, and anticipating new facts of tomorrow. In other words, he thinks in three dimensions of time; past, present, and future.
Few will deny that even in the first scientific instruction in mathematics the most rigorous method is to be given preference over all others. Especially will every teacher prefer a consistent proof to one which is based on fallacies or proceeds in a vicious circle, indeed it will be morally impossible for the teacher to present a proof of the latter kind consciously and thus in a sense deceive his pupils. Notwithstanding these objectionable so-called proofs, so far as the foundation and the development of the system is concerned, predominate in our textbooks to the present time. Perhaps it will be answered, that rigorous proof is found too difficult for the pupil’s power of comprehension. Should this be anywhere the case,—which would only indicate some defect in the plan or treatment of the whole,—the only remedy would be to merely state the theorem in a historic way, and forego a proof with the frank confession that no proof has been found which could be comprehended by the pupil; a remedy which is ever doubtful and should only be applied in the case of extreme necessity. But this remedy is to be preferred to a proof which is no proof, and is therefore either wholly unintelligible to the pupil, or deceives him with an appearance of knowledge which opens the door to all superficiality and lack of scientific method.
Finally, since I thought that we could have all the same thoughts, while asleep, as we have while we are awake, although none of them is true at that time, I decided to pretend that nothing that ever entered my mind was any more true than the illusions of my dreams. But I noticed, immediately afterwards, that while I thus wished to think that everything was false, it was necessarily the case that I, who was thinking this, was something. When I noticed that this truth “I think, therefore I am” was so firm and certain that all the most extravagant assumptions of the sceptics were unable to shake it, I judged that I could accept it without scruple as the first principle of the philosophy for which I was searching. Then, when I was examining what I was, I realized that I could pretend that I had no body, and that there was no world nor any place in which I was present, but I could not pretend in the same way that I did not exist. On the contrary, from the very fact that I was thinking of doubting the truth of other things, it followed very evidently and very certainly that I existed; whereas if I merely ceased to think, even if all the rest of what I had ever imagined were true, I would have no reason to believe that I existed. I knew from this that I was a substance, the whole essence or nature of which was to think and which, in order to exist, has no need of any place and does not depend on anything material. Thus this self—that is, the soul by which I am what I am—is completely distinct from the body and is even easier to know than it, and even if the body did not exist the soul would still be everything that it is.
Firm support has been found for the assertion that electricity occurs at thousands of points where we at most conjectured that it was present. Innumerable electrical particles oscillate in every flame and light source. We can in fact assume that every heat source is filled with electrons which will continue to oscillate ceaselessly and indefinitely. All these electrons leave their impression on the emitted rays. We can hope that experimental study of the radiation phenomena, which are exposed to various influences, but in particular to the effect of magnetism, will provide us with useful data concerning a new field, that of atomistic astronomy, as Lodge called it, populated with atoms and electrons instead of planets and worlds.
Food is at present obtained almost entirely from the energy of the sunlight. The radiation from the sun produces from the carbonic acid in the air more or less complicated carbon compounds which serve us in plants and vegetables. We use the latent chemical energy of these to keep our bodies warm, we convert it into muscular effort. We employ it in the complicated process of digestion to repair and replace the wasted cells of our bodies. … If the gigantic sources of power become available, food would be produced without recourse to sunlight. Vast cellars, in which artificial radiation is generated, may replace the cornfields and potato patches of the world.
For a billion years the patient earth amassed documents and inscribed them with signs and pictures which lay unnoticed and unused. Today, at last, they are waking up, because man has come to rouse them. Stones have begun to speak, because an ear is there to hear them. Layers become history and, released from the enchanted sleep of eternity, life’s motley, never-ending dance rises out of the black depths of the past into the light of the present.
For it is owing to their wonder that men now both begin and at first began to philosophize; they wondered originally at the obvious difficulties, then advanced little by little and stated difficulties about the greater matters, e.g. about the phenomena of the moon and those of the sun and the stars, and about the genesis of the universe. And a man who is puzzled and wonders thinks himself ignorant (whence even the lover of myth is in a sense a lover of wisdom, for myth is composed of wonders); therefore since they philosophized in order to escape from ignorance, evidently they were pursuing science in order to know, and not for any utilitarian end. And this is confirmed by the facts; for it was when almost all the necessities of life and the things that make for comfort and recreation were present, that such knowledge began to be sought. Evidently then we do not seek it for the sake of any advantage; but as the man is free, we say, who exists for himself and not for another, so we pursue this as the only free science, for it alone exists for itself.
For the time of making Observations none can ever be amiss; there being no season, nor indeed hardly any place where in some Natural Thing or other does not present it self worthy of Remark: yea there are some things that require Observation all the Year round, as Springs, Rivers, &c. Nor is there any Season amiss for the gathering Natural Things. Bodies of one kind or other presenting themselves at all times, and in Winter as well as Summer.
For the philosopher, order is the entirety of repetitions manifested, in the form of types or of laws, by perceived objects. Order is an intelligible relation. For the biologist, order is a sequence in space and time. However, according to Plato, all things arise out of their opposites. Order was born of the original disorder, and the long evolution responsible for the present biological order necessarily had to engender disorder.
An organism is a molecular society, and biological order is a kind of social order. Social order is opposed to revolution, which is an abrupt change of order, and to anarchy, which is the absence of order.
I am presenting here today both revolution and anarchy, for which I am fortunately not the only one responsible. However, anarchy cannot survive and prosper except in an ordered society, and revolution becomes sooner or later the new order. Viruses have not failed to follow the general law. They are strict parasites which, born of disorder, have created a very remarkable new order to ensure their own perpetuation.
An organism is a molecular society, and biological order is a kind of social order. Social order is opposed to revolution, which is an abrupt change of order, and to anarchy, which is the absence of order.
I am presenting here today both revolution and anarchy, for which I am fortunately not the only one responsible. However, anarchy cannot survive and prosper except in an ordered society, and revolution becomes sooner or later the new order. Viruses have not failed to follow the general law. They are strict parasites which, born of disorder, have created a very remarkable new order to ensure their own perpetuation.
For the sake of persons of ... different types, scientific truth should be presented in different forms, and should be regarded as equally scientific, whether it appears in the robust form and the vivid coloring of a physical illustration, or in the tenuity and paleness of a symbolic expression.
For what is that which we call evil but the absence of good? In the bodies of animals, disease and wounds mean nothing but the absence of health; for when a cure is effected, that does not mean that the evils which were present—namely, the diseases and wounds—go away from the body and dwell elsewhere: they altogether cease to exist; for the wound or disease is not a substance, but a defect in the fleshly substance,—the flesh itself being a substance, and therefore something good, of which those evils—that is, privations of the good which we call health—are accidents. Just in the same way, what are called vices in the soul are nothing but privations of natural good. And when they are cured, they are not transferred elsewhere: when they cease to exist in the healthy soul, they cannot exist anywhere else.
Forty years ago the philosopher Alfred North Whitehead thought it self-evident that you would get a good government if you took power out of the hands of the acquisitive and gave it to the learned and the cultivated. At present, a child in kindergarten knows better than that.
From very ancient times, the question of the constitution of matter with respect to divisibility has been debated, some adopting the opinion that this divisibility is infinite …. We have absolutely no means at our disposal for deciding such a question, which remains at the present day in the same state as when it first engaged the attention of the Greek philosophers, or perhaps that of the sages of Egypt and Hindostan long before them.
Furnished as all Europe now is with Academies of Science, with nice instruments and the spirit of experiment, the progress of human knowledge will be rapid and discoveries made of which we have at present no conception. I begin to be almost sorry I was born so soon, since I cannot have the happiness of knowing what will be known a hundred years hence.
Generally speaking, geologists seem to have been much more intent on making little worlds of their own, than in examining the crust of that which they inhabit. It would be much more desirable that facts should be placed in the foreground and theories in the distance, than that theories should be brought forward at the expense of facts. So that, in after times, when the speculations of the present day shall have passed away, from a greater accumulation of information, the facts may be readily seized and converted to account.
Geologists on the whole are inconsistent drivers. When a roadcut presents itself, they tend to lurch and weave. To them, the roadcut is a portal, a fragment of a regional story, a proscenium arch that leads their imaginations into the earth and through the surrounding terrane.
Geology, perhaps more than any other department of natural philosophy, is a science of contemplation. It requires no experience or complicated apparatus, no minute processes upon the unknown processes of matter. It demands only an enquiring mind and senses alive to the facts almost everywhere presented in nature. And as it may be acquired without much difficulty, so it may be improved without much painful exertion.
Germs of a theory, though in their present condition they are vague and formless … may be said to resemble stones in the quarry, rough and unhewn, but which may some time become corner-stones, columns, and entablatures in the future edifice.
Given for one instant an intelligence which could comprehend all the forces by which nature is animated and the respective situation of the beings which compose it—an intelligence sufficiently vast to submit these data to analysis, it would embrace in the same formula the movements of the greatest bodies in the universe and those of the lightest atom; to it nothing would be uncertain, and the future as the past would be present to its eyes.
God help the teacher, if a man of sensibility and genius, when a booby father presents him with his booby son, and insists on lighting up the rays of science in a fellow's head whose skull is impervious and inaccessible by any other way than a positive fracture with a cudgel.
Gold and iron at the present day, as in ancient times, are the rulers of the world; and the great events in the world of mineral art are not the discovery of new substances, but of new and rich localities of old ones.
Governments are trying to achieve unanimity by stifling any scientist who disagrees. Einstein could not have got funding under the present system.
Had I been present at the Creation, I would have given some useful hints for the better ordering of the universe.
Remarking on the complexity of Ptolemaic model of the universe after it was explained to him.
Footnote: Carlyle says, in his History of Frederick the Great, book ii. chap. vii. that this saying of Alphonso about Ptolemy's astronomy, 'that it seemed a crank machine; that it was pity the Creator had not taken advice,' is still remembered by mankind, — this and no other of his many sayings.
Remarking on the complexity of Ptolemaic model of the universe after it was explained to him.
Footnote: Carlyle says, in his History of Frederick the Great, book ii. chap. vii. that this saying of Alphonso about Ptolemy's astronomy, 'that it seemed a crank machine; that it was pity the Creator had not taken advice,' is still remembered by mankind, — this and no other of his many sayings.
He (Anaxagoras) is said to have been twenty years old at the time of Xerxes' crossing, and to have lived to seventy-two. Apollodorus says in his Chronicles that he was born in the seventieth Olympiad (500-497 B.C.) and died in the first year of the eighty-eighth (428/7). He began to be a philosopher at Athens in the archonship of Callias (456/5), at the age of twenty, as Demetrius Phalereus tells us in his Register of Archons, and they say he spent thirty years there. … There are different accounts given of his trial. Sotion, in his Succession of Philosophers, says that he was prosecuted by Cleon for impiety, because he maintained that the sun was a red hot mass of metal, and after that Pericles, his pupil, had made a speech in his defence, he was fined five talents and exiled. Satyrus in his Uves, on the other hand, says that the charge was brought by Thucydides in his political campaign against Pericles; and he adds that the charge was not only for the impiety but for Medism as well; and he was condemned to death in his absence. ... Finally he withdrew to Lampsacus, and there died. It is said that when the rulers of the city asked him what privilege he wished to be granted, he replied that the children should be given a holiday every year in the month in which he died. The custom is preserved to the present day. When he died the Lampsacenes buried him with full honours.
He will manage the cure best who has foreseen what is to happen from the present state of matters.
Hence when a person is in great pain, the cause of which he cannot remove, he sets his teeth firmly together, or bites some substance between them with great vehemence, as another mode of violent exertion to produce a temporary relief. Thus we have the proverb where no help can be has in pain, 'to grin and abide;' and the tortures of hell are said to be attended with 'gnashing of teeth.'Describing a suggestion of the origin of the grin in the present form of a proverb, 'to grin and bear it.'
Hence, wherever we meet with vital phenomena that present the two aspects, physical and psychical there naturally arises a question as to the relations in which these aspects stand to each other.
Here I shall present, without using Analysis [mathematics], the principles and general results of the Théorie, applying them to the most important questions of life, which are indeed, for the most part, only problems in probability. One may even say, strictly speaking, that almost all our knowledge is only probable; and in the small number of things that we are able to know with certainty, in the mathematical sciences themselves, the principal means of arriving at the truth—induction and analogy—are based on probabilities, so that the whole system of human knowledge is tied up with the theory set out in this essay.
Here the most sublime scene ever witnessed in the operating room was presented when the patient placed himself voluntarily upon the table, which was to become the altar of future fame. … The heroic bravery of the man who voluntarily placed himself upon the table, a subject for the surgeon’s knife, should be recorded and his name enrolled upon parchment, which should be hung upon the walls of the surgical amphitheatre in which the operation was performed. His name was Gilbert Abbott.
Description of the first public demonstration of ether at the Massachussetts General Hospital (16 Oct 1846).
Description of the first public demonstration of ether at the Massachussetts General Hospital (16 Oct 1846).
Hereafter we shall be compelled to acknowledge that the only distinction between species and well-marked varieties is, that the latter are known, or believed to be connected at the present day by intermediate gradations whereas species were formerly thus connected.
His mind illumined the Past and the Future and wrought greatly for the present. By his genius distant lands converse and men sail unafraid upon the deep.
— Epitaph
History is more or less bunk. It’s tradition. We want to live in the present and the only history that is worth a tinker’s damn is the history we make today.
History warns us … that it is the customary fate of new truths to begin as heresies and to end as superstitions; and, as matters now stand, it is hardly rash to anticipate that, in another twenty years, the new generation, educated under the influences of the present day, will be in danger of accepting the main doctrines of the “Origin of Species,” with as little reflection, and it may be with as little justification, as so many of our contemporaries, twenty years ago, rejected them.
History, human or geological, represents our hypothesis, couched in terms of past events, devised to explain our present-day observations.
How can a modern anthropologist embark upon a generalization with any hope of arriving at a satisfactory conclusion? By thinking of the organizational ideas that are present in any society as a mathematical pattern.
How paramount the future is to the present when one is surrounded by children.
However much we may enlarge our ideas of the time which has elapsed since the Niagara first began to drain the waters of the upper lakes, we have seen that this period was one only of a series, all belonging to the present zoological epoch; or that in which the living testaceous fauna, whether freshwater or marine, had already come into being. If such events can take place while the zoology of the earth remains almost stationary and unaltered, what ages may not be comprehended in those successive tertiary periods during which the Flora and Fauna of the globe have been almost entirely changed. Yet how subordinate a place in the long calendar of geological chronology do the successive tertiary periods themselves occupy! How much more enormous a duration must we assign to many antecedent revolutions of the earth and its inhabitants! No analogy can be found in the natural world to the immense scale of these divisions of past time, unless we contemplate the celestial spaces which have been measured by the astronomer.
Hubble's observations suggested that there was a time, called the big bang, when the universe was infinitesimally small and infinitely dense. Under such conditions all the laws of science, and therefore all ability to predict the future, would break down. If there were events earlier than this time, then they could not affect what happens at the present time. Their existence can be ignored because it would have no observational consequences. One may say that time had a beginning at the big bang, in the sense that earlier times simply would not be defined. It should be emphasized that this beginning in time is very different from those that had been considered previously. In an unchanging universe a beginning in time is something that has to be imposed by some being outside the universe; there is no physical necessity for a beginning. One can imagine that God created the universe at literally any time in the past. On the other hand, if the universe is expanding, there may be physical reasons why there had to be a beginning. One could still imagine that God created the universe at the instant of the big bang, or even afterwards in just such a way as to make it look as though there had been a big bang, but it would be meaningless to suppose that it was created before the big bang. An expanding universe does not preclude a creator, but it does place limits on when he might have carried out his job!
I ... express a wish that you may, in your generation, be fit to compare to a candle; that you may, like it, shine as lights to those about you; that, in all your actions, you may justify the beauty of the taper by making your deeds honourable and effectual in the discharge of your duty to your fellow-men.
[Concluding remarks for the final lecture (Christmas 1860-61) for children at the Royal Institution. These six lectures were the first series in the tradition of Christmas lectures continued to the present day.]
[Concluding remarks for the final lecture (Christmas 1860-61) for children at the Royal Institution. These six lectures were the first series in the tradition of Christmas lectures continued to the present day.]
I am born into an environment–I know not whence I came nor whither I go nor who I am. This is my situation as yours, every single one of you. The fact that everyone always was in this same situation, and always will be, tells me nothing. Our burning question as to the whence and whither–all we can ourselves observe about it is the present environment. That is why we are eager to find out about it as much as we can. That is science, learning, knowledge; it is the true source of every spiritual endeavour of man. We try to find out as much as we can about the spatial and temporal surroundings of the place in which we find ourselves put by birth.
I am much occupied with the investigation of the physical causes [of motions in the Solar System]. My aim in this is to show that the celestial machine is to be likened not to a divine organism but rather to a clockwork … insofar as nearly all the manifold movements are carried out by means of a single, quite simple magnetic force. This physical conception is to be presented through calculation and geometry.
I am not merely satisfied in making money for myself, for I am endeavoring to provide employment for hundreds of women of my race. ... I want to say to every Negro woman present, don't sit down and wait for the opportunities to come. Get up and make them!
I am now convinced that we have recently become possessed of experimental evidence of the discrete or grained nature of matter, which the atomic hypothesis sought in vain for hundreds and thousands of years. The isolation and counting of gaseous ions, on the one hand, which have crowned with success the long and brilliant researches of J.J. Thomson, and, on the other, agreement of the Brownian movement with the requirements of the kinetic hypothesis, established by many investigators and most conclusively by J. Perrin, justify the most cautious scientist in now speaking of the experimental proof of the atomic nature of matter, The atomic hypothesis is thus raised to the position of a scientifically well-founded theory, and can claim a place in a text-book intended for use as an introduction to the present state of our knowledge of General Chemistry.
I am of opinion, then, ... that, if there is any circumstance thoroughly established in geology, it is, that the crust of our globe has been subjected to a great and sudden revolution, the epoch of which cannot be dated much farther back than five or six thousand years ago; that this revolution had buried all the countries which were before inhabited by men and by the other animals that are now best known; that the same revolution had laid dry the bed of the last ocean, which now forms all the countries at present inhabited; that the small number of individuals of men and other animals that escaped from the effects of that great revolution, have since propagated and spread over the lands then newly laid dry; and consequently, that the human race has only resumed a progressive state of improvement since that epoch, by forming established societies, raising monuments, collecting natural facts, and constructing systems of science and of learning.
I am particularly concerned to determine the probability of causes and results, as exhibited in events that occur in large numbers, and to investigate the laws according to which that probability approaches a limit in proportion to the repetition of events. That investigation deserves the attention of mathematicians because of the analysis required. It is primarily there that the approximation of formulas that are functions of large numbers has its most important applications. The investigation will benefit observers in identifying the mean to be chosen among the results of their observations and the probability of the errors still to be apprehended. Lastly, the investigation is one that deserves the attention of philosophers in showing how in the final analysis there is a regularity underlying the very things that seem to us to pertain entirely to chance, and in unveiling the hidden but constant causes on which that regularity depends. It is on the regularity of the main outcomes of events taken in large numbers that various institutions depend, such as annuities, tontines, and insurance policies. Questions about those subjects, as well as about inoculation with vaccine and decisions of electoral assemblies, present no further difficulty in the light of my theory. I limit myself here to resolving the most general of them, but the importance of these concerns in civil life, the moral considerations that complicate them, and the voluminous data that they presuppose require a separate work.
I am stealing the golden vessels of the Egyptians to build a tabernacle to my God from them, far far away from the boundaries of Egypt. If you forgive me, I shall rejoice; if you are enraged with me, I shall bear it. See, I cast the die, and I write the book. Whether it is to be read by the people of the present or of the future makes no difference: let it await its reader for a hundred years, if God himself has stood ready for six thousand years for one to study him.
I ask myself whether the huge national commitment of technical talent to human spaceflight and the ever-present potential for the loss of precious human life are really justifiable.
I assume that each organism which the Creator educed was stamped with an indelible specific character, which made it what it was, and distinguished it from everything else, however near or like. I assume that such character has been, and is, indelible and immutable; that the characters which distinguish species now, were as definite at the first instant of their creation as now and are as distinct now as they were then. If any choose to maintain... that species were gradually bought to their present maturity from humbler forms... he is welcome to his hypothesis, but I have nothing to do with it.
I beg to present Columbus as a man of science and a man of faith. As a scientist, considering the time in which he lived, he eminently deserves our respect. Both in theory and in practice he was one of the best geographers and cosmographers of the age.
I believe … that we can still have a genre of scientific books suitable for and accessible alike to professionals and interested laypeople. The concepts of science, in all their richness and ambiguity, can be presented without any compromise, without any simplification counting as distortion, in language accessible to all intelligent people … I hope that this book can be read with profit both in seminars for graduate students and–if the movie stinks and you forgot your sleeping pills–on the businessman’s special to Tokyo.
I believe that the present laws of physics are at least incomplete without a translation into terms of mental phenomena.
I believe that, as men occupied with the study and treatment of disease, we cannot have too strong a conviction that the problems presented to us are physical problems, which perhaps we may never solve, but still admitting of solution only in one way, namely, by regarding them as part of an unbroken series, running up from the lowest elementary conditions of matter to the highest composition of organic structure.
I believe—and human psychologists, particularly psychoanalysts should test this—that present-day civilized man suffers from insufficient discharge of his aggressive drive. It is more than probable that the evil effects of the human aggressive drives, explained by Sigmund Freud as the results of a special death wish, simply derive from the fact that in prehistoric times intra-specific selection bred into man a measure of aggression drive for which in the social order today he finds no adequate outlet.
I can certainly wish for new, large, and properly constructed instruments, and enough of them, but to state where and by what means they are to be procured, this I cannot do. Tycho Brahe has given Mastlin an instrument of metal as a present, which would be very useful if Mastlin could afford the cost of transporting it from the Baltic, and if he could hope that it would travel such a long way undamaged… . One can really ask for nothing better for the observation of the sun than an opening in a tower and a protected place underneath.
I cannot but be astonished that Sarsi should persist in trying to prove by means of witnesses something that I may see for myself at any time by means of experiment. Witnesses are examined in doutbful matters which are past and transient, not in those which are actual and present. A judge must seek by means of witnesses to determine whether Peter injured John last night, but not whether John was injured, since the judge can see that for himself.
I consider [H. G. Wells], as a purely imaginative writer, to be deserving of very high praise, but our methods are entirely different. I have always made a point in my romances of basing my so-called inventions upon a groundwork of actual fact, and of using in their construction methods and materials which are not entirely without the pale of contemporary engineering skill and knowledge. ... The creations of Mr. Wells, on the other hand, belong unreservedly to an age and degree of scientific knowledge far removed from the present, though I will not say entirely beyond the limits of the possible.
I count Maxwell and Einstein, Eddington and Dirac, among “real” mathematicians. The great modern achievements of applied mathematics have been in relativity and quantum mechanics, and these subjects are at present at any rate, almost as “useless” as the theory of numbers.
I do not believe that the present flowering of science is due in the least to a real appreciation of the beauty and intellectual discipline of the subject. It is due simply to the fact that power, wealth and prestige can only be obtained by the correct application of science.
I do not think words alone will solve humanity’s present problems. The sound of bombs drowns out
men’s voices. In times of peace I have great faith in the communication of ideas among thinking men, but today, with brute force dominating so many millions of lives, I fear that the appeal to
man’s intellect is fast becoming virtually meaningless.
I do present you with a man of mine
Cunning in music and the mathematics
To instruct her fully in those sciences.
Cunning in music and the mathematics
To instruct her fully in those sciences.
I have destroyed almost the whole race of frogs, which does not happen in that savage Batrachomyomachia of Homer. For in the anatomy of frogs, which, by favour of my very excellent colleague D. Carolo Fracassato, I had set on foot in order to become more certain about the membranous substance of the lungs, it happened to me to see such things that not undeservedly I can better make use of that [saying] of Homer for the present matter—
“I see with my eyes a work trusty and great.”
For in this (frog anatomy) owing to the simplicity of the structure, and the almost complete transparency of the vessels which admits the eye into the interior, things are more clearly shown so that they will bring the light to other more obscure matters.
“I see with my eyes a work trusty and great.”
For in this (frog anatomy) owing to the simplicity of the structure, and the almost complete transparency of the vessels which admits the eye into the interior, things are more clearly shown so that they will bring the light to other more obscure matters.
I have long since come to see that no one deserves either praise or blame for the ideas that come to him, but only for the actions resulting therefrom. Ideas and beliefs are certainly not voluntary acts. They come to us—we hardly know how or whence, and once they have got possession of us we can not reject or change them at will. It is for the common good that the promulgation of ideas should be free—uninfluenced by either praise or blame, reward or punishment. But the actions which result from our ideas may properly be so treated, because it is only by patient thought and work, that new ideas, if good and true, become adopted and utilized; while, if untrue or if not adequately presented to the world, they are rejected or forgotten.
I have presented principles of philosophy that are not, however, philosophical but strictly mathematical—that is, those on which the study of philosophy can be based. These principles are the laws and conditions of motions and of forces, which especially relate to philosophy.
I have presented the periodic table as a kind of travel guide to an imaginary country, of which the elements are the various regions. This kingdom has a geography: the elements lie in particular juxtaposition to one another, and they are used to produce goods, much as a prairie produces wheat and a lake produces fish. It also has a history. Indeed, it has three kinds of history: the elements were discovered much as the lands of the world were discovered; the kingdom was mapped, just as the world was mapped, and the relative positions of the elements came to take on a great significance; and the elements have their own cosmic history, which can be traced back to the stars.
I have said that the investigation for which the teeth of the shark had furnished an opportunity, was very near an end... But thereafter, while I was examining more carefully these details of both places and bodies [sedimentary deposits and shells], these day by day presented points of doubt to me as they followed one another in indissoluble connection, so that I saw myself again and again brought back to the starting-place, as it were, when I thought I was nearest the goal. I might compare those doubts to the heads of the Lernean Hydra, since when one of them had been got rid of, numberless others were born; at any rate, I saw that I was wandering about in a sort of labyrinth, where the nearer one approaches the exit, the wider circuits does one tread.
I have stated, that in the thirteen species of ground-finches [in the Galapagos Islands], a nearly perfect gradation may be traced, from a beak extraordinarily thick, to one so fine, that it may be compared to that of a warbler. I very much suspect, that certain members of the series are confined to different islands; therefore, if the collection had been made on any one island, it would not have presented so perfect a gradation. It is clear, that if several islands have each their peculiar species of the same genera, when these are placed together, they will have a wide range of character. But there is not space in this work, to enter on this curious subject.
I have to keep going, as there are always people on my track. I have to publish my present work as rapidly as possible in order to keep in the race. The best sprinters in this road of investigation are Becquerel and the Curies...
I have tried to show why I believe that the biologist is the most romantic figure on earth at the present day. At first sight he seems to be just a poor little scrubby underpaid man, groping blindly amid the mazes of the ultra-microscopic, engaging in bitter and lifelong quarrels over the nephridia of flatworms, waking perhaps one morning to find that someone whose name he has never heard has demolished by a few crucial experiments the work which he had hoped would render him immortal.
I have witnessed a most remarkable drama here, one which to me as a German was very unexpected, and quite shocking. I saw the famous M. Lavoisier hold a ceremonial auto-da-fe of phlogiston in the Arsenal. His wife... served as the sacrificial priestess, and Stahl appeared as the advocatus diaboli to defend phlogiston. In the end, poor phlogiston was burned on the accusation of oxygen. Do you not think I have made a droll discovery? Everything is literally true. I will not say whether the cause of phlogiston is now irretrievably lost, or what I think about the issue. But I am glad that this spectacle was not presented in my fatherland.
I here present the reader with a new sign which I have discovered for detecting diseases of the chest. This consists in percussion of the human thorax, whereby, according to the character of the particular sounds then elicited, an opinion is formed of the internal state of that cavity.
I intentionally left the question of the origin of life uncanvassed as being altogether ultra vires in the present state of our knowledge.
I often use the analogy of a chess game: one can learn all the rules of chess, but one doesn’t know how to play well…. The present situation in physics is as if we know chess, but we don’t know one or two rules. But in this part of the board where things are in operation, those one or two rules are not operating much and we can get along pretty well without understanding those rules. That’s the way it is, I would say, regarding the phenomena of life, consciousness and so forth.
I ought to say that one of our first joint researches, so far as publication was concerned, had the peculiar effect of freeing me forever from the wiles of college football, and if that is a defect, make the most of it! Dr. Noyes and I conceived an idea on sodium aluminate solutions on the morning of the day of a Princeton-Harvard game (as I recall it) that we had planned to attend. It looked as though a few days' work on freezing-point determinations and electrical conductivities would answer the question. We could not wait, so we gave up the game and stayed in the laboratory. Our experiments were successful. I think that this was the last game I have ever cared about seeing. I mention this as a warning, because this immunity might attack anyone. I find that I still complainingly wonder at the present position of football in American education.
I publish this Essay in its present imperfect state, in order to prevent the furacious attempts of the prowling plagiary, and the insidious pretender to chymistry, from arrogating to themselves, and assuming my invention, in plundering silence: for there are those, who, if they can not be chymical, never fail by stratagem, and mechanical means, to deprive industry of the fruits, and fame of her labours.
I shall explain a System of the World differing in many particulars from any yet known, answering in all things to the common Rules of Mechanical Motions: This depends upon three Suppositions. First, That all Cœlestial Bodies whatsoever, have an attraction or gravitating power towards their own Centers, whereby they attract not only their own parts, and keep them from flying from them, as we may observe the Earth to do, but that they do also attract all the other Cœlestial bodies that are within the sphere of their activity; and consequently that not only the Sun and Moon have an influence upon the body and motion the Earth, and the Earth upon them, but that Mercury also Venus, Mars, Saturn and Jupiter by their attractive powers, have a considerable influence upon its motion in the same manner the corresponding attractive power of the Earth hath a considerable influence upon every one of their motions also. The second supposition is this, That all bodies whatsoever that are put into a direct and simple motion, will continue to move forward in a streight line, till they are by some other effectual powers deflected and bent into a Motion, describing a Circle, Ellipse, or some other more compounded Curve Line. The third supposition is, That these attractive powers are so much the more powerful in operating, by how much the nearer the body wrought upon is to their own Centers. Now what these several degrees are I have not yet experimentally verified; but it is a notion, which if fully prosecuted as it ought to be, will mightily assist the Astronomer to reduce all the Cœlestial Motions to a certain rule, which I doubt will never be done true without it. He that understands the nature of the Circular Pendulum and Circular Motion, will easily understand the whole ground of this Principle, and will know where to find direction in Nature for the true stating thereof. This I only hint at present to such as have ability and opportunity of prosecuting this Inquiry, and are not wanting of Industry for observing and calculating, wishing heartily such may be found, having myself many other things in hand which I would first compleat and therefore cannot so well attend it. But this I durst promise the Undertaker, that he will find all the Great Motions of the World to be influenced by this Principle, and that the true understanding thereof will be the true perfection of Astronomy.
I think I may fairly make two postulata. First, That food is necessary to the existence of man. Secondly, That the passion between the sexes is necessary and will remain nearly in its present state. These two laws ever since we have had any knowledge of mankind, appear to have been fixed laws of our nature; and, as we have not hitherto seen any alteration in them, we have no right to conclude that they will ever cease to be what they are now, without an immediate act of power in that Being who first arranged the system of the universe; and for the advantage of his creatures, still executes, according to fixed laws, all its various operations.
I think it would be just to say the most essential characteristic of mind is memory, using this word in its broadest sense to include every influence of past experience on present reactions.
I will insist particularly upon the following fact, which seems to me quite important and beyond the phenomena which one could expect to observe: The same [double sulfate of uranium and potassium] crystalline crusts, arranged the same way [as reported to the French academy on 24 Feb 1896] with respect to the photographic plates, in the same conditions and through the same screens, but sheltered from the excitation of incident rays and kept in darkness, still produce the same photographic images … [when kept from 26 Feb 1896] in the darkness of a bureau drawer. … I developed the photographic plates on the 1st of March, expecting to find the images very weak. Instead the silhouettes appeared with great intensity.
It is important to observe that it appears this phenomenon must not be attributed to the luminous radiation emitted by phosphorescence … One hypothesis which presents itself to the mind naturally enough would be to suppose that these rays, whose effects have a great similarity to the effects produced by the rays studied by M. Lenard and M. Röntgen, are invisible rays …
[Having eliminated phosphorescence as a cause, he has further revealed the effect of the as yet unknown radioactivity.]
It is important to observe that it appears this phenomenon must not be attributed to the luminous radiation emitted by phosphorescence … One hypothesis which presents itself to the mind naturally enough would be to suppose that these rays, whose effects have a great similarity to the effects produced by the rays studied by M. Lenard and M. Röntgen, are invisible rays …
[Having eliminated phosphorescence as a cause, he has further revealed the effect of the as yet unknown radioactivity.]
I, Galileo Galilei, son of the late Vincenzo Galilei, of Florence, aged seventy years, being brought personally to judgment, and kneeling before your Most Eminent and Most Reverend Lords Cardinals, General Inquisitors of the universal Christian republic against heretical depravity, having before my eyes the Holy Gospels, which I touch with my own hands, swear that I have always believed, and now believe, and with the help of God will in future believe, every article which the Holy Catholic and Apostolic Church of Rome holds, teaches, and preaches. But because I have been enjoined by this Holy Office altogether to abandon the false opinion which maintains that the sun is the centre and immovable, and forbidden to hold, defend, or teach the said false doctrine in any manner, and after it hath been signified to me that the said doctrine is repugnant with the Holy Scripture, I have written and printed a book, in which I treat of the same doctrine now condemned, and adduce reasons with great force in support of the same, without giving any solution, and therefore have been judged grievously suspected of heresy; that is to say, that I held and believed that the sun is the centre of the universe and is immovable, and that the earth is not the centre and is movable; willing, therefore, to remove from the minds of your Eminences, and of every Catholic Christian, this vehement suspicion rightfully entertained toward me, with a sincere heart and unfeigned faith, I abjure, curse, and detest the said errors and heresies, and generally every other error and sect contrary to Holy Church; and I swear that I will never more in future say or assert anything verbally, or in writing, which may give rise to a similar suspicion of me; but if I shall know any heretic, or anyone suspected of heresy, that I will denounce him to this Holy Office, or to the Inquisitor or Ordinary of the place where I may be; I swear, moreover, and promise, that I will fulfil and observe fully, all the penances which have been or shall be laid on me by this Holy Office. But if it shall happen that I violate any of my said promises, oaths, and protestations (which God avert!), I subject myself to all the pains and punishments which have been decreed and promulgated by the sacred canons, and other general and particular constitutions, against delinquents of this description. So may God help me, and his Holy Gospels which I touch with my own hands. I, the above-named Galileo Galilei, have abjured, sworn, promised, and bound myself as above, and in witness thereof with my own hand have subscribed this present writing of my abjuration, which I have recited word for word. At Rome, in the Convent of Minerva, June 22, 1633. I, Galileo Galilei, have abjured as above with my own hand.
If a little less time was devoted to the translation of letters by Julius Caesar describing Britain 2000 years ago and a little more time was spent on teaching children how to describe (in simple modern English) the method whereby ethylene was converted into polythene in 1933 in the ICI laboratories at Northwich, and to discussing the enormous social changes which have resulted from this discovery, then I believe that we should be training future leaders in this country to face the world of tomorrow far more effectively than we are at the present time.
If a mathematician of the past, an Archimedes or even a Descartes, could view the field of geometry in its present condition, the first feature to impress him would be its lack of concreteness. There are whole classes of geometric theories which proceed not only without models and diagrams, but without the slightest (apparent) use of spatial intuition. In the main this is due, to the power of the analytic instruments of investigations as compared with the purely geometric.
If an idea presents itself to us, we must not reject it simply because it does not agree with the logical deductions of a reigning theory.
If an organised body is not in the situation and circumstances best adapted to its sustenance and propagation, then, in conceiving an indefinite variety among the individuals of that species, we must be assured, that, on the one hand, those which depart most from the best adapted constitution, will be most liable to perish, while, on the other hand, those organised bodies, which most approach to the best constitution for the present circumstances, will be best adapted to continue, in preserving themselves and multiplying the individuals of their race.
If any spiritualistic medium can do stunts, there is no more need for special conditions than there is for a chemist to turn down lights, start operations with a hymn, and ask whether there's any chemical present that has affinity with something named Hydrogen.
If diphtheria is a disease caused by a microorganism, it is essential that three postulates be fulfilled. The fulfilment of these postulates is necessary in order to demonstrate strictly the parasitic nature of a disease:
1) The organism must be shown to be constantly present in characteristic form and arrangement in the diseased tissue.
2) The organism which, from its behaviour appears to be responsible for the disease, must be isolated and grown in pure culture.
3) The pure culture must be shown to induce the disease experimentally.
An early statement of Koch's postulates.
1) The organism must be shown to be constantly present in characteristic form and arrangement in the diseased tissue.
2) The organism which, from its behaviour appears to be responsible for the disease, must be isolated and grown in pure culture.
3) The pure culture must be shown to induce the disease experimentally.
An early statement of Koch's postulates.
If I were a comet, I should consider the men of our present age a degenerate breed. In former times, the respect for comets was universal and profound.
If I were asked to name the most needed of all reforms in the spirit of education, I should say: “Cease conceiving of education as mere preparation for later life, and make it the full meaning of the present life.”
[This is widely seen quoted in a paraphrased form: Education is not preparation for life; education is life itself.]
[This is widely seen quoted in a paraphrased form: Education is not preparation for life; education is life itself.]
If I would be a young man again and had to decide how to make my living, I would not try to become a scientist or scholar or teacher. I would rather choose to be a plumber or a peddler in the hope to find that modest degree of independence still available under present circumstances.
If in a given community unchecked popular rule means unlimited waste and destruction of the natural resources—soil, fertility, waterpower, forests, game, wild-life generally—which by right belong as much to subsequent generations as to the present generation, then it is sure proof that the present generation is not yet really fit for self-control, that it is not yet really fit to exercise the high and responsible privilege of a rule which shall be both by the people and for the people. The term “for the people” must always include the people unborn as well as the people now alive, or the democratic ideal is not realized.
If the average man in the street were asked to name the benefits derived from sunshine, he would probably say “light and warmth” and there he would stop. But, if we analyse the matter a little more deeply, we will soon realize that sunshine is the one great source of all forms of life and activity on this old planet of ours. … [M]athematics underlies present-day civilization in much the same far-reaching manner as sunshine underlies all forms of life, and that we unconsciously share the benefits conferred by the mathematical achievements of the race just as we unconsciously enjoy the blessings of the sunshine.
If the militarily most powerful—and least threatened—states need nuclear weapons for their security, how can one deny such security to countries that are truly insecure? The present nuclear policy is a recipe for proliferation. It is a policy for disaster.
If the mysterious influence to which the dissymmetry of nature is due should come to change in sense or direction, the constituting elements of all living beings would take an inverse dissymmetry. Perhaps a new world would be presented to us. Who could foresee the organization of living beings, if the cellulose, which is right, should become left, if the left albumen of the blood should become right? There are here mysteries which prepare immense labours for the future, and from this hour invite the most serious meditations in science.
If the present arrangements of society will not admit of woman’s free development, then society must be remodelled, and adapted to the great wants of humanity.
If the results of the present study on the chemical nature of the transforming principle are confirmed, then nucleic acids must be regarded as possessing biological specificity the chemical basis of which is as yet undetermined.
If the world has begun with a single quantum, the notions of space and would altogether fail to have any meaning at the beginning; they would only begin to have a sensible meaning when the original quantum had been divided into a sufficient number of quanta. If this suggestion is correct, the beginning of the world happened a little before the beginning of space and time. I think that such a beginning of the world is far enough from the present order of Nature to be not at all repugnant. It may be difficult to follow up the idea in detail as we are not yet able to count the quantum packets in every case. For example, it may be that an atomic nucleus must be counted as a unique quantum, the atomic number acting as a kind of quantum number. If the future development of quantum theory happens to turn in that direction, we could conceive the beginning of the universe in the form of a unique atom, the atomic weight of which is the total mass of the universe. This highly unstable atom would divide in smaller and smaller atoms by a kind of super-radioactive process.
If there ever was a misnomer, it is “exact science.” Science has always been full of mistakes. The present day is no exception. And our mistakes are good mistakes; they require a genius to correct. Of course, we do not see our own mistakes.
If there is any kind of animal which is female and has no male separate from it, it is possible that this may generate a young one from itself. No instance of this worthy of any credit has been observed up to the present at any rate, but one case in the class of fishes makes us hesitate. No male of the so-called erythrinus has ever yet been seen, but females, and specimens full of roe, have been seen. Of this, however, we have as yet no proof worthy of credit.
If these d'Hérelle bodies were really genes, fundamentally like our chromosome genes, they would give us an utterly new angle from which to attack the gene problem. They are filterable, to some extent isolable, can be handled in test-tubes, and their properties, as shown by their effects on the bacteria, can then be studied after treatment. It would be very rash to call these bodies genes, and yet at present we must confess that there is no distinction known between the genes and them. Hence we can not categorically deny that perhaps we may be able to grind genes in a mortar and cook them in a beaker after all. Must we geneticists become bacteriologists, physiological chemists and physicists, simultaneously with being zoologists and botanists? Let us hope so.
If this plane were to crash, we could get a new start on this quasar problem.
Said to colleagues, dramatically cupping his hand over his brow, shortly after the take-off of a propeller plane leaving Austin, Texas, after the Second Texas Symposium for Relativistic Astrophysics in Dec 1964. Various different theories had been presented at the conference. The flight passengers included many of the major scientists in quasar research, including Margaret and Geoffrey Burbridge, Subrahmanyan Chandrasekhar, John Wheeler and Maarten Schmidt.
Said to colleagues, dramatically cupping his hand over his brow, shortly after the take-off of a propeller plane leaving Austin, Texas, after the Second Texas Symposium for Relativistic Astrophysics in Dec 1964. Various different theories had been presented at the conference. The flight passengers included many of the major scientists in quasar research, including Margaret and Geoffrey Burbridge, Subrahmanyan Chandrasekhar, John Wheeler and Maarten Schmidt.
If we assume that there is only one enzyme present to act as an oxidizing agent, we must assume for it as many different degrees of activity as are required to explain the occurrence of the various colors known to mendelize (three in mice, yellow, brown, and black). If we assume that a different enzyme or group of enzymes is responsible for the production of each pigment we must suppose that in mice at least three such enzymes or groups of enzymes exist. To determine which of these conditions occurs in mice is not a problem f