[Shawn Lawrence Otto describes the damaging] strategy used to undermine science in the interest of those industries where science has pointed out the dangers of their products to individuals and human life in general … [It was] used a generation ago by the tobacco industry… First they manufacture uncertainty by raising doubts about even the most indisputable scientific evidence. Then they launder information by using seemingly independent front organizations to promote their desired message and thereby confuse the public. And finally they recruit unscrupulous scientific spokespeople to misrepresent peer-reviewed scientific findings and cherry-pick facts in an attempt to persuade the media and the public that there is still serious debate among scientists on the issue at hand.

Thomasina: Every week I plot your equations dot for dot, x’s against y’s in all manner of algebraical relation, and every week they draw themselves as commonplace geometry, as if the world of forms were nothing but arcs and angles. God’s truth, Septimus, if there is an equation for a curve like a bell, there must be an equation for one like a bluebell, and if a bluebell, why not a rose? Do we believe nature is written in numbers?
Septimus: We do.
Thomasina: Then why do your shapes describe only the shapes of manufacture?
Septimus: I do not know.
Thomasina: Armed thus, God could only make a cabinet.

A designer must always think about the unfortunate production engineer who will have to manufacture what you have designed; try to understand his problems.

A space station will permit quantum leaps in our research in science, communications, in metals, and in lifesaving medicines which could be manufactured only in space.

Agriculture is the foundation of manufactures, since the productions of nature are the materials of art.

Chemistry is not a primitive science like geometry and astronomy; it is constructed from the debris of a previous scientific formation; a formation half chimerical and half positive, itself found on the treasure slowly amassed by the practical discoveries of metallurgy, medicine, industry and domestic economy. It has to do with alchemy, which pretended to enrich its adepts by teaching them to manufacture gold and silver, to shield them from diseases by the preparation of the panacea, and, finally, to obtain for them perfect felicity by identifying them with the soul of the world and the universal spirit.

Electricity is but yet a new agent for the arts and manufactures, and, doubtless, generations unborn will regard with interest this century, in which it has been first applied to the wants of mankind.

Emotions are among the toughest things in the world to manufacture out of whole cloth; it is easier to manufacture seven facts than one emotion.

Engineering is the application of scientific and mathematical principles to practical ends such as the design, manufacture, and operation of efficient and economical structures, machines, processes, and systems.

Engineering is the art or science of utilizing, directing or instructing others in the utilization of the principles, forces, properties and substance of nature in the production, manufacture, construction, operation and use of things ... or of means, methods, machines, devices and structures ...

I favour both heavy industries and village industries. … I am in favour of heavy industries because heavy industries will save the money that is going out of the country in large sums every year; heavy industries are required to provide the local manufactures of machinery and equipment required by our railways and for defence forces and heavy industries are required also for supplying machinery and tools for the village industries themselves.

If we sink to the biochemical level, then the human being has lost a great many synthetic abilities possessed by other species and, in particular, by plants and microorganisms. Our loss of ability to manufacture a variety of vitamins makes us dependent on our diet and, therefore, on the greater synthetic versatility of other creatures. This is as much a “degenerative” change as the tapeworm’s abandonment of a stomach it no longer needs, but since we are prejudiced in our own favor, we don’t mention it.

It is a very strange thing to reflect that but for the invention of Professor Haber the Germans could not have continued the War after their original stack of nitrates was exhausted. The invention of this single man has enabled them, utilising the interval in which their accumulations were used up, not only to maintain an almost unlimited supply of explosives for all purposes, but to provide amply for the needs of agriculture in chemical manures. It is a remarkable fact, and shows on what obscure and accidental incidents the fortunes of possible the whole world may turn in these days of scientific discovery.
[During World War I, Fritz Haber and Karl Bosch invented a large scale process to cause the direct combination of hydrogen and nitrogen gases to chemically synthesize ammonia, thus providing a replacement for sodium nitrate in the manufacture of explosives and fertilizers.]

Men will not be content to manufacture life: they will want to improve on it.

Nature offers us a thousand simple pleasures—plays of light and color, fragrance in the air, the sun’s warmth on skin and muscle, the audible rhythm of life’s stir and push—for the price of merely paying attention. What joy! But how unwilling or unable many of us are to pay this price in an age when manufactured sources of stimulation and pleasure are everywhere at hand. For me, enjoying nature’s pleasures takes conscious choice, a choice to slow down to seed time or rock time, to still the clamoring ego, to set aside plans and busyness, and to simply to be present in my body, to offer myself up.

Now, we propose in the first place to show, that this law of organic progress is the law of all progress. Whether it be in the development of the Earth, in the development in Life upon its surface, in the development of Society, of Government, of Manufactures, of Commerce, of Language, Literature, Science, Art, this same evolution of the simple into the complex, through a process of continuous differentiation, holds throughout. From the earliest traceable cosmical changes down to the latest results of civilization, we shall find that the transformation of the homogeneous into the heterogeneous is that in which Progress essentially consists.

Science has been arranging, classifying, methodizing, simplifying, everything except itself. It has made possible the tremendous modern development of power of organization which has so multiplied the effective power of human effort as to make the differences from the past seem to be of kind rather than of degree. It has organized itself very imperfectly. Scientific men are only recently realizing that the principles which apply to success on a large scale in transportation and manufacture and general staff work to apply them; that the difference between a mob and an army does not depend upon occupation or purpose but upon human nature; that the effective power of a great number of scientific men may be increased by organization just as the effective power of a great number of laborers may be increased by military discipline.

Science has so accustomed us to devising and accepting theories to account for the facts we observe, however fantastic, that our minds must begin their manufacture before we are aware of it.

Since the discovery of oxygen the civilised world has undergone a revolution in manners and customs. The knowledge of the composition of the atmosphere, of the solid crust of the earth, of water, and of their influence upon the life of plants and animals, was linked to that discovery. The successful pursuit of innumerable trades and manufactures, the profitable separation of metals from their ores, also stand in the closest connection therewith.

The advancement of agriculture, commerce and manufactures, by all proper means, will not, I trust, need recommendation. But I cannot forbear intimating to you the expediency of giving effectual encouragement as well to the introduction of new and useful inventions from abroad, as to the exertions of skill and genius in producing them at home.

The Church saves sinners, but science seeks to stop their manufacture.

The mutton in the study gathered over it a thick blanket of Penicillium. On the 13th [December 1875] it had assumed a light brown colour as if by a faint admixture of clay; but the infusion became transparent. The ‘clay’ here was the slime of dead or dormant Bacteria, the cause of their quiescence being the blanket of Penicillium. I found no active life in this tube, while all the others swarmed with Bacteria. In every case where the mould was thick and coherent the Bacteria died, or became dormant, and fell to the bottom of the sediment … The Bacteria which manufacture a green pigment appear to be uniformly victorious in their fight with the Penicillium.

The pace of science forces the pace of technique. Theoretical physics forces atomic energy on us; the successful production of the fission bomb forces upon us the manufacture of the hydrogen bomb. We do not choose our problems, we do not choose our products; we are pushed, we are forced—by what? By a system which has no purpose and goal transcending it, and which makes man its appendix.

The private motives of scientists are not the trend of science. The trend of science is made by the needs of society: navigation before the eighteenth century, manufacture thereafter; and in our age I believe the liberation of personality. Whatever the part which scientists like to act, or for that matter which painters like to dress, science shares the aims of our society just as art does.

The responsibility for maintaining the composition of the blood in respect to other constituents devolves largely upon the kidneys. It is no exaggeration to say that the composition of the blood is determined not by what the mouth ingests but by what the kidneys keep; they are the master chemists of our internal environment, which, so to speak, they synthesize in reverse. When, among other duties, they excrete the ashes of our body fires, or remove from the blood the infinite variety of foreign substances which are constantly being absorbed from our indiscriminate gastrointestinal tracts, these excretory operations are incidental to the major task of keeping our internal environment in an ideal, balanced state. Our glands, our muscles, our bones, our tendons, even our brains, are called upon to do only one kind of physiological work, while our kidneys are called upon to perform an innumerable variety of operations. Bones can break, muscles can atrophy, glands can loaf, even the brain can go to sleep, without immediately endangering our survival, but when the kidneys fail to manufacture the proper kind of blood neither bone, muscle, gland nor brain can carry on.

The school of Plato has advanced the interests of the race as much through geometry as through philosophy. The modern engineer, the navigator, the astronomer, built on the truths which those early Greeks discovered in their purely speculative investigations. And if the poetry, statesmanship, oratory, and philosophy of our day owe much to Plato’s divine Dialogues, our commerce, our manufactures, and our science are equally indebted to his Conic Sections. Later instances may be abundantly quoted, to show that the labors of the mathematician have outlasted those of the statesman, and wrought mightier changes in the condition of the world. Not that we would rank the geometer above the patriot, but we claim that he is worthy of equal honor.

There are those who say that the human kidney was created to keep the blood pure, or more precisely, to keep our internal environment in an ideal balanced state. This I must deny. I grant that the human kidney is a marvelous organ, but I cannot grant that it was purposefully designed to excrete urine or to regulate the composition of the blood or to subserve the physiological welfare of Homo sapiens in any sense. Rather I contend that the human kidney manufactures the kind of urine that it does, and it maintains the blood in the composition which that fluid has, because this kidney has a certain functional architecture; and it owes that architecture not to design or foresight or to any plan, but to the fact that the earth is an unstable sphere with a fragile crust, to the geologic revolutions that for six hundred million years have raised and lowered continents and seas, to the predacious enemies, and heat and cold, and storms and droughts; to the unending succession of vicissitudes that have driven the mutant vertebrates from sea into fresh water, into desiccated swamps, out upon the dry land, from one habitation to another, perpetually in search of the free and independent life, perpetually failing, for one reason or another, to find it.

There is romance, the genuine glinting stuff, in typewriters, and not merely in their development from clumsy giants into agile dwarfs, but in the history of their manufacture, which is filled with raids, battles, lonely pioneers, great gambles, hope, fear, despair, triumph. If some of our novels could be written by the typewriters instead of on them, how much better they would be.

This extraordinary metal [iron], the soul of every manufacture, and the mainspring perhaps of civilised society.

What we call man is a mechanism made up of … uncrystallized matter … all the colloid matter of his mechanism is concentrated in a countless number of small cells. … [T]hese cells [are] dwelling places, communes, a walled town within which are many citizens. ... [T]hese are the units of life and when they pass out into space man as we think we know him is dead, a mere machine from which the crew have left,so to speak. ... [T]hese units are endowed with great intelligence. They have memories, they must be divided into countless thousands of groups, most are workers, there are directing groups. Some are chemists, they manufacture the most complicated chemicals that are secreted by the glands.