Penicillium Quotes (3 quotes)
By teaching us how to cultivate each ferment in its purity—in other words, by teaching us how to rear the individual organism apart from all others,—Pasteur has enabled us to avoid all these errors. And where this isolation of a particular organism has been duly effected it grows and multiplies indefinitely, but no change of it into another organism is ever observed. In Pasteur’s researches the Bacterium remained a Bacterium, the Vibrio a Vibrio, the Penicillium a Penicillium, and the Torula a Torula. Sow any of these in a state of purity in an appropriate liquid; you get it, and it alone, in the subsequent crop. In like manner, sow smallpox in the human body, your crop is smallpox. Sow there scarlatina, and your crop is scarlatina. Sow typhoid virus, your crop is typhoid—cholera, your crop is cholera. The disease bears as constant a relation to its contagium as the microscopic organisms just enumerated do to their germs, or indeed as a thistle does to its seed.
It has been demonstrated that a species of penicillium produces in culture a very powerful antibacterial substance which affects different bacteria in different degrees. Generally speaking it may be said that the least sensitive bacteria are the Gram-negative bacilli, and the most susceptible are the pyogenic cocci ... In addition to its possible use in the treatment of bacterial infections penicillin is certainly useful... for its power of inhibiting unwanted microbes in bacterial cultures so that penicillin insensitive bacteria can readily be isolated.
The mutton in the study gathered over it a thick blanket of Penicillium. On the 13th [December 1875] it had assumed a light brown colour as if by a faint admixture of clay; but the infusion became transparent. The ‘clay’ here was the slime of dead or dormant Bacteria, the cause of their quiescence being the blanket of Penicillium. I found no active life in this tube, while all the others swarmed with Bacteria. In every case where the mould was thick and coherent the Bacteria died, or became dormant, and fell to the bottom of the sediment … The Bacteria which manufacture a green pigment appear to be uniformly victorious in their fight with the Penicillium.