Ex ovo omnia.
Everything out of the egg.

Although it be a known thing subscribed by all, that the foetus assumes its origin and birth from the male and female, and consequently that the egge is produced by the cock and henne, and the chicken out of the egge, yet neither the schools of physicians nor Aristotle’s discerning brain have disclosed the manner how the cock and its seed doth mint and coin the chicken out of the egge.

And so I conclude that blood lives and is nourished of itself and in no way depends on any other part of the body as being prior to it or more excellent... So that from this we may perceive the causes not only of life in general... but also of longer or shorter life, of sleeping and waking, of skill, of strength and so forth.

Everyone admits that the male is the primary efficient cause in generation, as being that in whom the species or form resides, and they further assert that his genitures emitted in coitus causes the egg both to exist and to be fertile. But how the semen of the cock produces the chick from the egg, neither the philosophers nor the physicians of yesterday or today have satisfactorily explained, or solved the problem formulated by Aristotle.

I finally saw that the blood, forced by the action of the left ventricle into the arteries, was distributed to the body at large, and its several parts, in the same manner as it is sent through the lungs, impelled by the right ventricle into the pulmonary artery, and that it then passed through the veins and along the vena cava, and so round to the left ventricle in the manner already indicated. Which motion we may be allowed to call circular, in the same way as Aristotle says that the air and the rain emulate the circular motion of the superior bodies; for the moist earth, warmed by the sun, evaporates; the vapours drawn upwards are condensed, and descending in the form of rain, moisten the earth again; and by this arrangement are generations of living things produced.

I profess to learn and to teach anatomy not from books but from dissections, not from the tenets of Philosophers but from the fabric of Nature.

In attempting to discover how much blood passes from the veins into the arteries I made dissections of living animals, opened up arteries in them, and carried out various other investigations. I also considered the symmetry and size of the ventricles of the heart and of the vessels which enter and leave them (since Nature, who does nothing purposelessly, would not purposelessly have given these vessels such relatively large size). I also recalled the elegant and carefully contrived valves and fibres and other structural artistry of the heart; and many other points. I considered rather often and with care all this evidence, and took correspondingly long trying to assess how much blood was transmitted and in how short a time. I also noted that the juice of the ingested food could not supply this amount without our having the veins, on the one hand, completely emptied and the arteries, on the other hand, brought to bursting through excessive inthrust of blood, unless the blood somehow flowed back again from the arteries into the veins and returned to the right ventricle of the heart. In consequence, I began privately to consider that it had a movement, as it were, in a circle.

In man, then, let us take the amount that is extruded by the individual beats, and that cannot return into the heart because of the barrier set in its way by the valves, as half an ounce, or three drachms, or at least one drachm. In half an hour the heart makes over a thousand beats; indeed, in some individuals, and on occasion, two, three, or four thousand. If you multiply the drachms per beat by the number of beats you will see that in half an hour either a thousand times three drachms or times two drachms, or five hundred ounces, or other such proportionate quantity of blood has been passed through the heart into the arteries, that is, in all cases blood in greater amount than can be found in the whole of the body. Similarly in the sheep or the dog. Let us take it that one scruple passes in a single contraction of the heart; then in half an hour a thousand scruples, or three and a half pounds of blood, do so. In a body of this size, as I have found in the sheep, there is often not more than four pounds of blood.
In the above sort of way, by calculating the amount of blood transmitted [at each heart beat] and by making a count of the beats, let us convince ourselves that the whole amount of the blood mass goes through the heart from the veins to the arteries and similarly makes the pulmonary transit.
Even if this may take more than half an hour or an hour or a day for its accomplishment, it does nevertheless show that the beat of the heart is continuously driving through that organ more blood than the ingested food can supply, or all the veins together at any time contain.

It is, however, an argument of no weight to say that natural bodies are first generated or compounded out of those things into which they are at the last broken down or dissolved.

Nature is nowhere accustomed more openly to display her secret mysteries than in cases where she shows tracings of her workings apart from the beaten paths; nor is there any better way to advance the proper practice of medicine than to give our minds to the discovery of the usual law of nature, by careful investigation of cases of rarer forms of disease.

The animal's heart is the basis of its life, its chief member, the sun of its microcosm; on the heart all its activity depends, from the heart all its liveliness and strength arise. Equally is the king the basis of his kingdoms, the sun of his microcosm, the heart of the state; from him all power arises and all grace stems.

The blood in the animal body is impelled in a circle and is in a state of ceaseless motion … and that it is the sole and only end of the motion and contraction of the heart.

There is no science which does not spring from pre-existing knowledge, and no certain and definite idea which has not derived its origin from the senses.

This organ deserves to be styled the starting point of life and the sun of our microcosm just as much as the sun deserves to be styled the heart of the world. For it is by the heart's vigorous beat that the blood is moved, perfected, activated, and protected from injury and coagulation. The heart is the tutelary deity of the body, the basis of life, the source of all things, carrying out its function of nourishing, warming, and activating body as a whole. But we shall more fittingly speak of these matters when we consider the final cause of this kind of movement.

We, however, maintain … that all animals whatsoever, even the viviparous, and man himself not excepted, are produced from ova; that the first conception, from which the foetus proceeds in all, is an ovum of one description or another, as well as the seeds of all kinds of plants.

What remains to be said is of so novel and unheard of a character that I not only fear injury to myself from the envy of a few, but I tremble lest I have mankind at large for my enemies, so much to wont and custom that become as another nature, and doctrine once sown that hath struck deep root, and respect for antiquity, influence all men.

When in many dissections, carried out as opportunity offered upon living animals, I first addressed my mind to seeing how I could discover the function and offices of the heart’s movement in animals through the use of my own eyes instead of through the books and writings of others, I kept finding the matter so truly hard and beset with difficulties that I all but thought, with Fracastoro, that the heart's movement had been understood by God alone.

And when with excellent Microscopes I discern in otherwise invisible Objects the Inimitable Subtlety of Nature’s Curious Workmanship; And when, in a word, by the help of Anatomicall Knives, and the light of Chymicall Furnaces, I study the Book of Nature, and consult the Glosses of Aristotle, Epicurus, Paracelsus, Harvey, Helmont, and other learn'd Expositors of that instructive Volumne; I find my self oftentimes reduc’d to exclaim with the Psalmist, How manifold are thy works, O Lord? In wisdom hast thou made them all.

In science, address the few; in literature, the many. In science, the few must dictate opinion to the many; in literature, the many, sooner or later, force their judgement on the few. But the few and the many are not necessarily the few and the many of the passing time: for discoverers in science have not un-often, in their own day, had the few against them; and writers the most permanently popular not unfrequently found, in their own day, a frigid reception from the many. By the few, I mean those who must ever remain the few, from whose dieta we, the multitude, take fame upon trust; by the many, I mean those who constitute the multitude in the long-run. We take the fame of a Harvey or a Newton upon trust, from the verdict of the few in successive generations; but the few could never persuade us to take poets and novelists on trust. We, the many, judge for ourselves of Shakespeare and Cervantes.

Coy Nature, (which remain'd, though aged grown,
A beauteous virgin still, enjoy'd by none,
Nor seen unveil'd by anyone),
When Harvey's violent passion she did see,
Began to tremble and to flee;
Took sanctuary, like Daphne, in a tree:
There Daphne’s Lover stopped, and thought it much
The very leaves of her to touch:
But Harvey, our Apollo, stopp’d not so;
Into the Bark and Root he after her did go!

He [William Harvey] bid me to goe to the Fountain-head, and read Aristotle, Cicero, Avicenna, and did call the Neoteriques shitt-breeches.

I have heard him [William Harvey] say, that after his Booke of the Circulation of the Blood came-out, that he fell mightily in his Practize, and that 'twas beleeved by the vulgar that he was crack-brained.

He [William Harvey] did not care for chymistrey, and was wont to speake against them with an undervalue.

Only by following out the injunction of our great predecessor [William Harvey] to search out and study the secrets of Nature by way of experiment, can we hope to attain to a comprehension of 'the wisdom of the body and the understanding of the heart,' and thereby to the mastery of disease and pain, which will enable us to relieve the burden of mankind.

Power politics existed before Machiavelli was ever heard of; it will exist long after his name is only a faint memory. What he did, like Harvey, was to recognize its existence and subject it to scientific study.

… our “Physick” and “Anatomy” have embraced such infinite varieties of being, have laid open such new worlds in time and space, have grappled, not unsuccessfully, with such complex problems, that the eyes of Vesalius and of Harvey might be dazzled by the sight of the tree that has grown out of their grain of mustard seed.

Seeing and thinking have done much for human progress; in the sphere of mind and morals everything, and could the world have been saved by armchair philosophy, the Greeks would have done it; but only a novum organon could do this, the powerful possibilities of which were only revealed when man began to search our the secrets of nature by way of experiment, to use the words of Harvey.

The Chinese, who aspire to be thought an enlightened nation, to this day are ignorant of the circulation of the blood; and even in England the man who made that noble discovery lost all his practice in the consequence of his ingenuity; and Hume informs us that no physician in the United Kingdom who had attained the age of forty ever submitted to become a convert to Harvey’s theory, but went on preferring numpsimus to sumpsimus to the day of his death.

One of the greatest experimental scientists of the time who was really doing something, William Harvey, said that what Bacon said science was, was the science that a lord-chancellor would do. He [Bacon] spoke of making observations, but omitted the vital factor of judgment about what to observe and what to pay attention to.