… however useful the words may have been in the past, they have now become handicaps to the further development of knowledge. Words like botany and zoology imply that plants and animals are quite different things. … But the differences rapidly become blurred when we start looking at the world through a microscope. … The similarities between plants and animals became more important than their differences with the discoveries that both were built up of cells, had sexual reproduction,… nutrition and respiration … and with the development of evolutionary theory.

...the genes almost always accurately reproduce. If they don't, you get one of the following results: One, monsters—that is, grossly malformed babies resulting from genetic mistakes. Years ago most monsters died, but now many can be saved. This has made possible the National Football League.

Ode to The Amoeba
Recall from Time's abysmal chasm
That piece of primal protoplasm
The First Amoeba, strangely splendid,
From whom we're all of us descended.
That First Amoeba, weirdly clever,
Exists today and shall forever,
Because he reproduced by fission;
He split himself, and each division
And subdivision deemed it fitting
To keep on splitting, splitting, splitting;
So, whatsoe'er their billions be,
All, all amoebas still are he.
Zoologists discern his features
In every sort of breathing creatures,
Since all of every living species,
No matter how their breed increases
Or how their ranks have been recruited,
From him alone were evoluted.
King Solomon, the Queen of Sheba
And Hoover sprang from that amoeba;
Columbus, Shakespeare, Darwin, Shelley
Derived from that same bit of jelly.
So famed is he and well-connected,
His statue ought to be erected,
For you and I and William Beebe
Are undeniably amoebae!

A hen is only an egg's way of making another egg.

A large proportion of mankind, like pigeons and partridges, on reaching maturity, having passed through a period of playfulness or promiscuity, establish what they hope and expect will be a permanent and fertile mating relationship. This we call marriage.

A new species develops if a population which has become geographically isolated from its parental species acquires during this period of isolation characters which promote or guarantee reproductive isolation when the external barriers break down.

A species is a reproductive community of populations (reproductively isolated from others) that occupies a specific niche in nature.

A weird happening has occurred in the case of a lansquenet named Daniel Burghammer, of the squadron of Captain Burkhard Laymann Zu Liebenau, of the honorable Madrucci Regiment in Piadena, in Italy. When the same was on the point of going to bed one night he complained to his wife, to whom he had been married by the Church seven years ago, that he had great pains in his belly and felt something stirring therein. An hour thereafter he gave birth to a child, a girl. When his wife was made aware of this, she notified the occurrence at once. Thereupon he was examined and questioned. … He confessed on the spot that he was half man and half woman and that for more than seven years he had served as a soldier in Hungary and the Netherlands… . When he was born he was christened as a boy and given in baptism the name of Daniel… . He also stated that while in the Netherlands he only slept once with a Spaniard, and he became pregnant therefrom. This, however, he kept a secret unto himself and also from his wife, with whom he had for seven years lived in wedlock, but he had never been able to get her with child… . The aforesaid soldier is able to suckle the child with his right breast only and not at all on the left side, where he is a man. He has also the natural organs of a man for passing water. Both are well, the child is beautiful, and many towns have already wished to adopt it, which, however, has not as yet been arranged. All this has been set down and described by notaries. It is considered in Italy to be a great miracle, and is to be recorded in the chronicles. The couple, however, are to be divorced by the clergy.

All animals whatsoever, whether they fly or swim or walk upon dry land, whether they bring forth their young alive or in the egg, develop in the same way.

All the different classes of beings which taken together make up the universe are, in the ideas of God who knows distinctly their essential gradations, only so many ordinates of a single curve so closely united that it would be impossible to place others between any two of them, since that would imply disorder and imperfection. Thus men are linked with the animals, these with the plants and these with the fossils which in turn merge with those bodies which our senses and our imagination represent to us as absolutely inanimate. And, since the law of continuity requires that when the essential attributes of one being approximate those of another all the properties of the one must likewise gradually approximate those of the other, it is necessary that all the orders of natural beings form but a single chain, in which the various classes, like so many rings, are so closely linked one to another that it is impossible for the senses or the imagination to determine precisely the point at which one ends and the next begins?all the species which, so to say, lie near the borderlands being equivocal, at endowed with characters which might equally well be assigned to either of the neighboring species. Thus there is nothing monstrous in the existence zoophytes, or plant-animals, as Budaeus calls them; on the contrary, it is wholly in keeping with the order of nature that they should exist. And so great is the force of the principle of continuity, to my thinking, that not only should I not be surprised to hear that such beings had been discovered?creatures which in some of their properties, such as nutrition or reproduction, might pass equally well for animals or for plants, and which thus overturn the current laws based upon the supposition of a perfect and absolute separation of the different orders of coexistent beings which fill the universe;?not only, I say, should I not be surprised to hear that they had been discovered, but, in fact, I am convinced that there must be such creatures, and that natural history will perhaps some day become acquainted with them, when it has further studied that infinity of living things whose small size conceals them for ordinary observation and which are hidden in the bowels of the earth and the depth of the sea.

Altering a gene in the gene line to produce improved offspring is likely to be very difficult because of the danger of unwanted side effects. It would also raise obvious ethical problems.

And therefore though Adam was framed without this part (a navel), as having no other womb than that of his proper principles, yet was not his posterity without the same: for the seminality of his fabric contained the power thereof; and was endued with the science of those parts whose predestinations upon succession it did accomplish.

Animals generally seem naturally disposed to … intercourse at about the same period of the year, and that is when winter is changing into summer…. In the human species, the male experiences more under sexual excitement in winter, and the female in summer.

Anybody who looks at living organisms knows perfectly well that they can produce other organisms like themselves. This is their normal function, they wouldn’t exist if they didn’t do this, and it’s not plausible that this is the reason why they abound in the world. In other words, living organisms are very complicated aggregations of elementary parts, and by any reasonable theory of probability or thermodynamics highly improbable. That they should occur in the world at all is a miracle of the first magnitude; the only thing which removes, or mitigates, this miracle is that they reproduce themselves. Therefore, if by any peculiar accident there should ever be one of them, from there on the rules of probability do not apply, and there will be many of them, at least if the milieu is reasonable. But a reasonable milieu is already a thermodynamically much less improbable thing. So, the operations of probability somehow leave a loophole at this point, and it is by the process of self-reproduction that they are pierced.

Be fruitful and multiply, and then fill the earth and subdue it.

Birth, and copulation, and death.
That’s all the facts when you come to brass tacks:
Birth, and copulation, and death
I’ve been born, and once is enough.

But if we are to control evolution we shall have to find out how to influence gene reproduction in a definite direction, just as organic chemists nowadays work for definite ends. Such a possibility is at present entirely beyond our grasp, but a century hence it may not be so.

By the act of generation nothing more is done than to ferment the sperm of ye female by the sperm of ye male that it may thereby become fit nourishment for ye Embryo: ffor ye nourishment of all animals is prepared by ferment & the ferment is taken from animals of the same kind, & makes the nourishment subtile & spiritual. In adult animals the nourishm^t is fermented by the choler and pancreatic juice both w^ch come from the blood. The Embryo not being able to ferment its own nourishment w^ch comes from the mothers blood has it fermented by the sperm w^ch comes from ye fathers blood, & by this nourishment it swells, drops off from ye Ovarium & begins to grow with a life distinct from that of ye mother.

Cell genetics led us to investigate cell mechanics. Cell mechanics now compels us to infer the structures underlying it. In seeking the mechanism of heredity and variation we are thus discovering the molecular basis of growth and reproduction. The theory of the cell revealed the unity of living processes; the study of the cell is beginning to reveal their physical foundations.

Domesticated salmon, after several generations, are fat, listless things that are good at putting on weight, not swimming up fast-moving rivers. When they get into a river and breed with wild fish, they can damage the wild fish's prospects of surviving to reproduce.

Each year, it seems, larger and more daunting mountains of text rise from the lush lowlands of visual reproduction.

Everyone admits that the male is the primary efficient cause in generation, as being that in whom the species or form resides, and they further assert that his genitures emitted in coitus causes the egg both to exist and to be fertile. But how the semen of the cock produces the chick from the egg, neither the philosophers nor the physicians of yesterday or today have satisfactorily explained, or solved the problem formulated by Aristotle.

Five per cent vision is better than no vision at all. Five per cent hearing is better than no hearing at all. Five per cent flight efficiency is better than no flight at all. It is thoroughly believable that every organ or apparatus that we actually see is the product of a smooth trajectory through animal space, a trajectory in which every intermediate stage assisted survival and reproduction.
[Rebutting the Creationist assertion that fully developed organs could not have arisen 'by chance.']

From the sexual, or amatorial, generation of plants new varieties, or improvements, are frequently obtained; as many of the young plants from seeds are dissimilar to the parent, and some of them superior to the parent in the qualities we wish to possess... Sexual reproduction is the chef d'oeuvre, the master-piece of nature.

Furthermore, it’s equally evident that what goes on is actually one degree better than self-reproduction, for organisms appear to have gotten more elaborate in the course of time. Today's organisms are phylogenetically descended from others which were vastly simpler than they are, so much simpler, in fact, that it’s inconceivable, how any kind of description of the latter, complex organism could have existed in the earlier one. It’s not easy to imagine in what sense a gene, which is probably a low order affair, can contain a description of the human being which will come from it. But in this case you can say that since the gene has its effect only within another human organism, it probably need not contain a complete description of what is to happen, but only a few cues for a few alternatives. However, this is not so in phylogenetic evolution. That starts from simple entities, surrounded by an unliving amorphous milieu, and produce, something more complicated. Evidently, these organisms have the ability to produce something more complicated than themselves.

Generation by male and female is a law common to animals and plants.

Human consciousness is just about the last surviving mystery. A mystery is a phenomenon that people don’t know how to think about—yet. There have been other great mysteries: the mystery of the origin of the universe, the mystery of life and reproduction, the mystery of the design to be found in nature, the mysteries of time, space, and gravity. These were not just areas of scientific ignorance, but of utter bafflement and wonder. We do not yet have the final answers to any of the questions of cosmology and particle physics, molecular genetics and evolutionary theory, but we do know how to think about them. The mysteries haven't vanished, but they have been tamed. They no longer overwhelm our efforts to think about the phenomena, because now we know how to tell the misbegotten questions from the right questions, and even if we turn out to be dead wrong about some of the currently accepted answers, we know how to go about looking for better answers. With consciousness, however, we are still in a terrible muddle. Consciousness stands alone today as a topic that often leaves even the most sophisticated thinkers tongue-tied and confused. And, as with all the earlier mysteries, there are many who insist—and hope—that there will never be a demystification of consciousness.

I will give no deadly medicine to any one if asked, nor suggest any such counsel; and in like manner I will not give any woman the instrument to procure abortion. … I will not cut a person who is suffering with stone, but will leave this to be done by men who are practitioners of such work.

I would be content that we might procreate like trees, without conjunction, or that there were any way to perpetuate the World without this trivial and vulgar way of coition.

If the earth’s population continues to double every 50 years (as it is now doing) then by 2550 A.D. it will have increased 3,000-fold. … by 2800 A.D., it would reach 630,000 billion! Our planet would have standing room only, for there would be only two-and-a-half square feet per person on the entire land surface, including Greenland and Antarctica. In fact, if the human species could be imagined as continuing to multiply further at the same rate, by 4200 A.D. the total mass of human tissue would be equal to the mass of the earth.

If there is any kind of animal which is female and has no male separate from it, it is possible that this may generate a young one from itself. No instance of this worthy of any credit has been observed up to the present at any rate, but one case in the class of fishes makes us hesitate. No male of the so-called erythrinus has ever yet been seen, but females, and specimens full of roe, have been seen. Of this, however, we have as yet no proof worthy of credit.

If we reflect that a small creature such as this is provided, not only with external members, but also with intestines and other organs, we have no reason to doubt that a like creature, even if a thousand million times smaller, may already be provided with all its external and internal organs... though they may be hidden from our eyes. For, if we consider the external and internal organs of animalcules which are so small that a thousand million of them together would amount to the size of a coarse grain of sand, it may well be, however incomprehensible and unsearchable it may seem to us, that an animalcule from the male seed of whatever members of the animal kingdom, contains within itself... all the limbs and organs which an animal has when it is born.

In order to drive the individuals towards reproduction, sexuality had therefore to be associated with some other devices. Among these was pleasure. … Thus pleasure appears as a mere expedient to push individuals to indulge in sex and therefore to reproduce. A rather successful expedient indeed as judged by the state of the world population.

In trying to evaluate Hopkins' unique contribution to biochemistry it may perhaps be said that he alone amongst his contemporaries succeeded in formulating the subject. Among others whose several achievements in their own fields may have surpassed his, no one has ever attempted to unify and correlate biochemical knowledge so as to form a comprehensible picture of the cell and its relation to life, reproduction and function.

It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
[Concluding remark in the paper by Watson and Crick announcing discovery of the structure of DNA.]

It is interesting to contemplate an entangled bank, clothed with many plants of many kinds, with birds singing on the bushes, with various insects flitting about, and with worms crawling through the damp earth, and to reflect that these elaborately constructed forms, so different from each other, and dependent on each other in so complex a manner, have all been produced by laws acting around us. These laws, taken in the largest sense, being Growth with Reproduction; Inheritance which is almost implied by reproduction; Variability from the indirect and direct action of the external conditions of life, and from use and disuse; a Ratio of Increase so high as to lead to a Struggle for Life, and as a consequence to Natural Selection, entailing Divergence of Character and the Extinction of less-improved forms.

It is not always the magnitude of the differences observed between species that must determine specific distinctions, but the constant preservation of those differences in reproduction.

It is raining DNA outside. On the bank of the Oxford canal at the bottom of my garden is a large willow tree, and it is pumping downy seeds into the air. ... [spreading] DNA whose coded characters spell out specific instructions for building willow trees that will shed a new generation of downy seeds. … It is raining instructions out there; it’s raining programs; it’s raining tree-growing, fluff-spreading, algorithms. That is not a metaphor, it is the plain truth. It couldn’t be any plainer if it were raining floppy discs.

It is the object of science to replace, or save, experiences, by the reproduction and anticipation of facts in thought. Memory is handier than experience, and often answers the same purpose. This economical office of science, which fills its whole life, is apparent at first glance; and with its full recognition all mysticism in science disappears.

It may very properly be asked whether the attempt to define distinct species, of a more or less permanent nature, such as we are accustomed to deal with amongst the higher plants and animals, is not altogether illusory amongst such lowly organised forms of life as the bacteria. No biologist nowadays believes in the absolute fixity of species … but there are two circumstances which here render the problem of specificity even more difficult of solution. The bacteriologist is deprived of the test of mutual fertility or sterility, so valuable in determining specific limits amongst organisms in which sexual reproduction prevails. Further, the extreme rapidity with which generation succeeds generation amongst bacteria offers to the forces of variation and natural selection a field for their operation wholly unparalleled amongst higher forms of life.

It was to Hofmeister, working as a young man, an amateur and enthusiast, in the early morning hours of summer months, before business, at Leipzig in the years before 1851, that the vision first appeared of a common type of Life-Cycle, running through Mosses and Ferns to Gymnosperms and Flowering Plants, linking the whole series in one scheme of reproduction and life-history.

Leaving aside genetic surgery applied humans, I foresee that the coming century will place in our hands two other forms of biological technology which are less dangerous but still revolutionary enough to transform the conditions of our existence. I count these new technologies as powerful allies in the attack on Bernal's three enemies. I give them the names “biological engineering” and “self-reproducing machinery.” Biological engineering means the artificial synthesis of living organisms designed to fulfil human purposes. Self-reproducing machinery means the imitation of the function and reproduction of a living organism with non-living materials, a computer-program imitating the function of DNA and a miniature factory imitating the functions of protein molecules. After we have attained a complete understanding of the principles of organization and development of a simple multicellular organism, both of these avenues of technological exploitation should be open to us.

Let us investigate more closely this property common to animal and plant, this power of producing its likeness, this chain of successive existences of individuals, which constitutes the real existence of the species.

Life has found ways to flourish in boiling hot springs and on icy mountain tops, to fly, glow in the dark, put forth leaves in a rainless desert, or plumb the ocean, reproducing and adapting, reincarnating itself in new forms in defiance of time and death.

Macduff was from his mother’s womb Untimely rip’d.

Man continues to be the only 150 pound nonlinear servomechanism that can be wholly mass-produced by unskilled labor.

Men in most cases continue to be sexually competent until they are sixty years old, and if that limit be overpassed then until seventy years; and men have been actually known to procreate children at seventy years of age.

Might one not say that in the chance combination of nature's production, since only those endowed with certain relations of suitability could survive, it is no cause for wonder that this suitability is found in all species that exist today? Chance, one might say, produced an innumerable multitude of individuals; a small number turned out to be constructed in such fashion that the parts of the animal could satisfy its needs; in another, infinitely greater number, there was neither suitability nor order: all of the later have perished; animals without a mouth could not live, others lacking organs for reproduction could not perpetuate themselves: the only ones to have remained are those in which were found order and suitability; and these species, which we see today, are only the smallest part of what blind fate produced.

Modern times breed modern phobias. Until the present age, for example, it has been impossible for any woman to suffer crippling fear of artificial insemination.

Natural selection based on the differential multiplication of variant types cannot exist before there is material capable of replicating itself and its own variations, that is, before the origination of specifically genetic material or gene-material.

No species … possesses a purpose beyond the imperatives created by genetic history … The human mind is a device for survival and reproduction, and reason is just one of its various techniques.

Not only do the various components of the cells form a living system, in which the capacity to live, react, and reproduce is dependent on the interactions of all the members of the system; but this living system is identical with the genetic system. The form of life is determined not only by the specific nature of the hereditary units but also by the structure and arrangement of the system. The whole system is more than the sum of its parts, and the effect of each of the components depends on and is influenced by all previous reactions, whose sequence is in turn determined by the whole idiotype.

Our immediate interests are after all of but small moment. It is what we do for the future, what we add to the sum of man's knowledge, that counts most. As someone has said, 'The individual withers and the world is more and more.' Man dies at 70, 80, or 90, or at some earlier age, but through his power of physical reproduction, and with the means that he has to transmit the results of effort to those who come after him, he may be said to be immortal.

Reproduction anywhere in the world of photographic pictures and all kinds of drawings or records.

Reproduction is so primitive and fundamental a function of vital organisms that the mechanism by which it is assured is highly complex and not yet clearly understood. It is not necessarily connected with sex, nor is sex necessarily connected with reproduction.

Second Law
All the acquisitions or losses wrought by nature on individuals, through the influence of the environment in which their race has long been placed, and hence through the influence of the predominant use or permanent disuse of any organ; all these are preserved by reproduction to the new individuals which arise, provided that the acquired modifications are common to both sexes, or at least to the individuals which produce the young.

Since natural selection demands only adequacy, elegance of design is not relevant; any combination of behavioural adjustment, physiological regulation, or anatomical accommodation that allows survival and reproduction may be favoured by selection. Since all animals are caught in a phylogenetic trap by the nature of past evolutionary adjustments, it is to be expected that a given environmental challenge will be met in a variety of ways by different animals. The delineation of the patterns of the accommodations of diverse types of organisms to the environment contributes much of the fascination of ecologically relevant physiology.

So the Lord God caused a deep sleep to fall upon the man, and while he slept took one of his ribs and closed up its place with flesh; and the rib which the Lord God had taken from the man he made into a woman and brought her to the man.

That a woman should at present be almost driven from society, for an offence [illegitimate childbearing], which men commit nearly with impunity, seems to be undoubtedly a breach of natural justice… . What at first might be dictated by state necessity, is now supported by female delicacy; and operates with the greatest force on that part of society, where, if the original intention of the custom were preserved, there is the least real occasion for it.

The essential molecule of reproduction, DNA, … is composed of only four nitrogen bases (adenine, thymine, guanine, and cytosine), the sugar deoxyribose, and a phosphate. DNA’s intermediary, RNA, differs only by the substitution of the sugar ribose for deoxyribose and the nitrogen base uracil for thymine. The proteins of living organisms are made with a mere 20 amino acids, all arranged in a “left-handed” configuration. Taking into account all 28 building blocks, or “letters” (20 amino acids, five bases, two sugars, and one phosphate), the message is clear: With such a limited alphabet, all life must have had a common chemical origin.

The History of Evolution of Organisms consists of two kindred and closely connected parts: Ontogeny, which is the history of the evolution of individual organisms, and Phylogeny, which is the history of the evolution of organic tribes. Ontogency is a brief and rapid recapitulation of Phylogeny, dependent on the physiological functions of Heredity (reproduction) and Adaptation (nutrition). The individual organism reproduces in the rapid and short course of its own evolution the most important of the changes in form through which its ancestors, according to laws of Heredity and Adaptation, have passed in the slow and long course of their palaeontological evolution.

The reproduction of mankind is a great marvel and mystery. Had God consulted me in the matter, I should have advised him to continue the generation of the species by fashioning them of clay.

The Reproductions of the living Ens
From sires to sons, unknown to sex, commence...
Unknown to sex the pregnant oyster swells,
And coral-insects build their radiate shells...
Birth after birth the line unchanging runs,
And fathers live transmitted in their sons;
Each passing year beholds the unvarying kinds,
The same their manners, and the same their minds.

The solar system was formed 4.6 billion years ago, and the oldest fossils on Earth have been dated at about 3.8 billion years. Sometime between these two points, the chemicals of the young planet were organized into the responsive, reproducing systems we call “life.”

The succession of individuals, connected by reproduction and belonging to a species, makes it possible for the specific form itself to last for ages. In the end, however, the species is temporary; it has no “eternal life.” After existing for a certain period, it either dies or is converted by modification into other forms.

There is a finite number of species of plants and animals—even of insects—upon the earth. … Moreover, the universality of the genetic code, the common character of proteins in different species, the generality of cellular structure and cellular reproduction, the basic similarity of energy metabolism in all species and of photosynthesis in green plants and bacteria, and the universal evolution of living forms through mutation and natural selection all lead inescapably to a conclusion that, although diversity may be great, the laws of life, based on similarities, are finite in number and comprehensible to us in the main even now.

There is in Nature a general prototype in each species on which each individual is modeled, but which seems, in realizing itself, to alter itself or perfect itself according to circumstances. So that, relative to certain qualities, this is an extraordinary appearing variation in the succession of these individuals, and at the same time a constancy which appears wonderful in the entire species. The first animal, the first horse, for example, has been the external model and the interieur mold on which all horses which have been born, all those which now exist, and all those which will be born have been formed.

Thus ordered thinking arises out of the ordered course of nature in which man finds himself, and this thinking is from the beginning nothing more than the subjective reproduction of the regularity according to the law of natural phenomena. On the other hand, this reproduction is only possible by means of the will that controls the concatenation of ideas.

To ask what qualities distinguish good from routine scientific research is to address a question that should be of central concern to every scientist. We can make the question more tractable by rephrasing it, “What attributes are shared by the scientific works which have contributed importantly to our understanding of the physical world—in this case the world of living things?” Two of the most widely accepted characteristics of good scientific work are generality of application and originality of conception. . These qualities are easy to point out in the works of others and, of course extremely difficult to achieve in one’s own research. At first hearing novelty and generality appear to be mutually exclusive, but they really are not. They just have different frames of reference. Novelty has a human frame of reference; generality has a biological frame of reference. Consider, for example, Darwinian Natural Selection. It offers a mechanism so widely applicable as to be almost coexistent with reproduction, so universal as to be almost axiomatic, and so innovative that it shook, and continues to shake, man’s perception of causality.

To say that there is a soul in stones simply in order to account for their production is unsatisfactory: for their production is not like the reproduction of living plants, and of animals which have senses. For all these we see reproducing their own species from their own seeds; and a stone does not do this at all. We never see stones reproduced from stones; ... because a stone seems to have no reproductive power at all.

We are consuming our forests three times faster than they are being reproduced. Some of the richest timber lands of this continent have already been destroyed, and not replaced, and other vast areas are on the verge of destruction. Yet forests, unlike mines, can be so handled as to yield the best results of use, without exhaustion, just like grain fields.

We are machines built by DNA whose purpose is to make more copies of the same DNA. ... This is exactly what we are for. We are machines for propagating DNA, and the propagation of DNA is a self-sustaining process. It is every living object's sole reason for living.

When ultra-violet light acts on a mixture of water, carbon dioxide, and ammonia, a vast variety of organic substances are made, including sugars and apparently some of the materials from which proteins are built up…. But before the origin of life they must have accumulated till the primitive oceans reached the consistency of hot dilute soup…. The first living or half-living things were probably large molecules synthesized under the influence of the sun’s radiation, and only capable of reproduction in the particularly favorable medium in which they originated….

You say Beasts are Machines like Watches? But put the Machine called a Dog, and the Machine called a Bitch to one another for some time, and there may result another little Machine; whereas two Watches might be together all their Life-time, without ever producing a third Watch. Now Madam de B— and I think, according to our Philosophy, that all things which being but two, are endued with the Virtue of making themselves three, are of a much higher Nature than a Machine.